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1

Reimers, H. K. O. "De jaarrekeningprocedure na Hoge Raad inzake Spyker." Maandblad Voor Accountancy en Bedrijfseconomie 84, no. 5 (2010): 237–43. http://dx.doi.org/10.5117/mab.84.16930.

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Het oordeel van de Hoge Raad over de jaarrekening van Spyker biedt belangrijke inzichten voor het toezicht op de financiële verslaggeving en de jaarrekeningprocedure. Hoe de rechter omgaat met het IFRS-toetsingskader, de ruimte voor de Ondernemingskamer om een herziening van de jaarrekening te bevelen, de rol van de Ondernemingskamer en van de accountant in de procedure worden besproken. De beschikking van de Hoge Raad legt diverse knelpunten in het toezicht op verslaggeving en de jaarrekeningprocedure bloot, maar geeft ook duidelijkheid.
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Reimers, H. K. O. "De uitspraak van de Ondernemingskamer in AFM versus Spyker." Maandblad Voor Accountancy en Bedrijfseconomie 82, no. 7/8 (2008): 334–39. http://dx.doi.org/10.5117/mab.82.20850.

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De Autoriteit Financiële Markten (AFM) heeft haar eerste jaarrekeningprocedure bij de Ondernemingskamer (OK) verloren en is daartegen inmiddels in cassatie gegaan. De uitspraak bevestigt dat het bestuur van een onderneming bij interpretatie van open normen en feiten de nodige vrijheid heeft. Gebruik van deze vrijheid wordt slechts marginaal getoetst. Gezien de uitkomst van de procedure lijkt de AFM volgens de OK bij haar toezicht op basis van de Wet toezicht fi nanciële verslaggeving (Wtfv) een andere toetsing te hanteren dan die de OK voorstaat. Mocht de Hoge Raad in cassatie niet tot een and
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3

Dieleman, Anton. "Toezicht op financiële verslaggeving, getrouw beeld en discretionaire bevoegdheden." Maandblad Voor Accountancy en Bedrijfseconomie 85, no. 3 (2011): 156–63. http://dx.doi.org/10.5117/mab.85.15766.

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naar aanleiding van de uitspraken van de Ondernemingskamer en de Hoge raad met betrekking tot de jaarrekening 2006 van Spyker wordt in dit artikel een analyse gegeven van een aantal relevante elementen uit die uitspraak. Aandacht wordt besteed aan het concept van het ‘getrouw beeld’ en de invloed van materiële fouten daarop. Vervolgens wordt op basis daarvan de zogenaamde discretionaire bevoegdheid van de AFm en de Ondernemingskamer behandeld. Tot slot besteedt het artikel aandacht aan ontbrekende toelichtingen in de jaarrekening die wel in het jaarverslag zijn opgenomen en op de wijze waarop
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4

Hoogendoorn, Martin. "Materialiteit." Maandblad Voor Accountancy en Bedrijfseconomie 85, no. 4 (2011): 184–85. http://dx.doi.org/10.5117/mab.85.16348.

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In 1996 promoveerde mijn collega De Bos op een proefschrift over presentatiematerialiteit. Naar mijn waarneming heeft het onderwerp daarna lange tijd weinig aandacht gehad. Maar dat het onderwerp nu tot veel discussie aanleiding geeft, blijkt uit artikelen in dit blad van Reimers (2010) en Dieleman (2011) naar aanleiding van de jaarrekeningprocedure inzake Spyker, en van Litjens (2011) naar aanleiding van het in november 2010 door de Autoriteit Financiële Markten (AFM) gepubliceerde rapport ‘Aandachtspunten Financiële Verslaggeving 2010’. En die aandacht is terecht. Zo lijkt de AFM materiële g
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Dick, Michael, Peter Fromm, and Jochen Wagner. "Der Audi R8 Spyder." ATZ - Automobiltechnische Zeitschrift 112, no. 3 (2010): 179–93. http://dx.doi.org/10.1007/bf03222149.

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6

Karn, Shashank. "Spyder Parental Control Android Application." International Journal for Research in Applied Science and Engineering Technology 8, no. 5 (2020): 2140–44. http://dx.doi.org/10.22214/ijraset.2020.5351.

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7

Schlott, Stefan. "Die Manufaktur des Porsche 918 Spyder." ATZ - Automobiltechnische Zeitschrift 115, no. 10 (2013): 814–17. http://dx.doi.org/10.1007/s35148-013-0280-3.

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8

Romario, M. Hamsy, Eko Ihsanto, and Trie Maya Kadarina. "Sistem Hitung dan Klasifikasi Objek dengan Metode Convolutional Neural Network." Jurnal Teknologi Elektro 11, no. 2 (2020): 108. http://dx.doi.org/10.22441/jte.2020.v11i2.007.

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Sistem klasifikasi objek ini di rancang untuk melakukan klasifikasi dan perhitungan jumlah objek terdeteksi pada suatu gambar. menggunakan metode Convolutional Neural Network yang telah dilatih, Metode CNN merupakan salah satu metode deep learning yang mampu melakukan proses pembelajaran mandiri untuk pengenalan objek, ekstraksi objek dan klasifikasi serta dapat diterapkan pada citra resolusi tinggi yang memiliki model distribusi nonparametrik. Kemudian gambar yang telah diterima dijalankan menggunakan Bahasa pemrograman python pada laptop operasional menggunakan platform open source spyder3.
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9

Iseli, Christian, and Eduardo Sanchez. "Spyder: A SURE (SUperscalar and REconfigurable) processor." Journal of Supercomputing 9, no. 3 (1995): 231–52. http://dx.doi.org/10.1007/bf01212870.

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10

Enbody, Richard J., and David H. C. Du. "SPYDER: a serial/parallel goal-directed router." Integration 7, no. 2 (1989): 151–87. http://dx.doi.org/10.1016/0167-9260(89)90035-7.

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11

Priambodo, Ardy Seto. "STUDI KOMPARASI SIMULASI SISTEM KENDALI PID PADA MATLAB, GNU OCTAVE, SCILAB DAN SPYDER." Elinvo (Electronics, Informatics, and Vocational Education) 4, no. 2 (2019): 169–75. http://dx.doi.org/10.21831/elinvo.v4i2.28347.

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Dalam penelitian ini perbandingan antara perangkat lunak MATLAB, GNU Octave, Scilab dan Spyder akan diamati. Proses yang menjadi obyek dalam penelitian ini adalah sistem kendali PID yang digunakan untuk mengendalikan plant yang berupa model motor DC. Fungsi alih dari motor DC merupakan model dari motor DC yang diturunkan dari hukum newton ke-2 dan hukum kirchoff tegangan. Simulasi dilakukan pada perangkat lunak menggunakan 2 cara yaitu kode program dan block programming. Jumlah baris kode program yang terpendek adalah MATLAB dengan 17 baris dan yang terpanjang adalah Spyder dengan 20 baris kod
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12

Modest, C., and F. Thielecke. "SPYDER: a software package for system diagnosis engineering." CEAS Aeronautical Journal 7, no. 2 (2016): 315–31. http://dx.doi.org/10.1007/s13272-016-0189-0.

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13

Sokol’skaya, M. A., V. A. Shvartz, and O. L. Bockeria. "Experience in the use of wireless system “Spyder” for multi-day monitoring of electrocardiogram." Annaly aritmologii 15, no. 4 (2018): 213–19. http://dx.doi.org/10.15275/annaritmol.2018.4.3.

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14

Abdulhak, Ismail, and Trent Andrew Smith. "The $845,000 Porsche 918 Hybrid Spyder: Redefining the Supercar." Deakin Papers on International Business Economics 4, no. 1 (2011): 37. http://dx.doi.org/10.21153/dpibe2011vol4no1art183.

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As a result of the role of the automobile in contributing to carbon emissions and in symbolizing the overconsumption of scarce no n-renewable fuel reso urces coupled with the increased media focus on climat e change governments all over the world are intervening in the automobile market with regulation. Rising world oil prices and consumer preferences for enviro nmentally friendly goods has driven automobile manufacture rs to research, develop an d market alternative drive systems. Such advancements are now commo n in the family car market with hybrid electric as well as fully electric cars no
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15

Malone, S. "SPYDERS on the Internet." Seismological Research Letters 67, no. 5 (1996): 58–63. http://dx.doi.org/10.1785/gssrl.67.5.58.

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Sumby, Paul, Shizhen Zhang, Adeline R. Whitney, et al. "A Chemokine-Degrading Extracellular Protease Made by Group A Streptococcus Alters Pathogenesis by Enhancing Evasion of the Innate Immune Response." Infection and Immunity 76, no. 3 (2008): 978–85. http://dx.doi.org/10.1128/iai.01354-07.

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ABSTRACT Circumvention of the host innate immune response is critical for bacterial pathogens to infect and cause disease. Here we demonstrate that the group A Streptococcus (GAS; Streptococcus pyogenes) protease SpyCEP (S. pyogenes cell envelope protease) cleaves granulocyte chemotactic protein 2 (GCP-2) and growth-related oncogene alpha (GROα), two potent chemokines made abundantly in human tonsils. Cleavage of GCP-2 and GROα by SpyCEP abrogated their abilities to prime neutrophils for activation, detrimentally altering the innate immune response. SpyCEP expression is negatively regulated by
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17

Chomba, B. K., D. B. O. Konditi, D. M. Nyaanga, and J. M. Githeko. "Effects of Varying Distance on Wireless Signal Propagation in Indoor and Outdoor Built Sites." International Journal of Engineering Research in Africa 6 (November 2011): 75–89. http://dx.doi.org/10.4028/www.scientific.net/jera.6.75.

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The effects of varying distances on wireless signal propagation in indoor and outdoor built sites is presented in this paper. In indoor and outdoor built sites the major RF signal attenuation is due to multi-path interference, signal loss (fading), and non-line of sight signal blockage. A number of mobile communication systems is currently and frequently being used in indoor environments based on IEEE 802.11b standards which is on 2.4GHz frequency ISM band at the rate of 11Mbps. To determine the effects of varying distances on signal strength at 2.457 GHz, a Spykee spy Wi-Fi robot was used as
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18

Biancari, Fausto, Jarmo Lahtinen, Risto Ojala, et al. "Spyder Aortic Connector System in Off-Pump Coronary Artery Bypass Surgery." Annals of Thoracic Surgery 84, no. 1 (2007): 254–57. http://dx.doi.org/10.1016/j.athoracsur.2007.02.022.

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19

Li, Jinquan, Hui Zhu, Wenchao Feng, et al. "Regulation of Inhibition of Neutrophil Infiltration by the Two-Component Regulatory System CovRS in Subcutaneous Murine Infection with Group A Streptococcus." Infection and Immunity 81, no. 3 (2013): 974–83. http://dx.doi.org/10.1128/iai.01218-12.

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ABSTRACTHypervirulent invasive group A streptococcus (GAS) isolates inhibit neutrophil infiltration more than pharyngitis isolates do, and the molecular basis of this difference is not well understood. This study was designed to first determine whether natural null mutation of the two-component regulatory system CovRS is responsible for the enhancement of the inhibition of neutrophil recruitment seen in hypervirulent GAS. Next, we examined the role of CovRS-regulated interleukin-8/CXC chemokine peptidase (SpyCEP), C5a peptidase (ScpA), and platelet-activating factor acetylhydrolase (SsE) in th
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20

Schussler, Jeffrey M., Cory H. White, Michael A. Fontes, Stewart A. Master, and Baron L. Hamman. "Spyder™ Proximal Coronary Vein Graft Patency over Time: The SPPOT Study." Heart Surgery Forum 12, no. 1 (2009): E49—E53. http://dx.doi.org/10.1532/hsf98.20081124.

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21

Jong-Seo Kim. "United States v. Windsor, Executor of the Estate of Spyer, et al." Democratic Legal Studies ll, no. 53 (2013): 275–354. http://dx.doi.org/10.15756/dls.2013..53.275.

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22

Bradke, Brian, and Bradford Everman. "Investigation of Photoplethysmography Behind the Ear for Pulse Oximetry in Hypoxic Conditions with a Novel Device (SPYDR)." Biosensors 10, no. 4 (2020): 34. http://dx.doi.org/10.3390/bios10040034.

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Photoplethysmography (PPG) is a valuable technique for noninvasively evaluating physiological parameters. However, traditional PPG devices have significant limitations in high-motion and low-perfusion environments. To overcome these limitations, we investigated the accuracy of a clinically novel PPG site using SPYDR®, a new PPG sensor suite, against arterial blood gas (ABG) measurements as well as other commercial PPG sensors at the finger and forehead in hypoxic environments. SPYDR utilizes a reflectance PPG sensor applied behind the ear, between the pinna and the hairline, on the mastoid pro
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23

Baldessar, Maria José. "Conectado: o que a Internet fez com você e o que você pode fazer com ela." Brazilian Journalism Research 4, no. 2 (2008): 195–98. http://dx.doi.org/10.25200/bjr.v4n2.2008.172.

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Um livro interessante, embora de leitura simples e rápida. Assim é “Conectado: o que a internet fez com você e o que você pode fazer com ela”, do historiador Juliano Spyer, lançado pela Jorge Zahar Editora, em fins de 2007. Já no prefácio de Caio Túlio Costa encontramos um relato dos primórdios da rede e de como ela era usada por jornalistas e pesquisadores. E olha que esses primórdios, no caso de Caio Túlio, datam o ano de 1988.
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24

Jona Lasinio, Giovanna, Alessio Pollice, and Elisa Anna Fano. "Generalized biodiversity assessment by Bayesian nested random effects models with spyke-and-slab priors." Statistics & Probability Letters 144 (January 2019): 52–56. http://dx.doi.org/10.1016/j.spl.2018.03.006.

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25

Bradke, Brian S., Tiffany A. Miller, and Bradford Everman. "Photoplethysmography behind the Ear Outperforms Electrocardiogram for Cardiovascular Monitoring in Dynamic Environments." Sensors 21, no. 13 (2021): 4543. http://dx.doi.org/10.3390/s21134543.

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An increasing proportion of occupational mishaps in dynamic, high-risk operational environments have been attributed to human error, yet there are currently no devices to routinely provide accurate physiological data for insights into underlying contributing factors. This is most commonly due to limitations of commercial and clinical devices for collecting physiological data in environments of high motion. Herein, a novel Photoplethysmography (PPG) sensor device was tested, called SPYDR (Standalone Performance Yielding Deliberate Risk), reading from a behind-the-ear location, specifically desi
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Hamman, Baron L., Cory H. White, Michael Fontes, and Lise Labiche. "Clampless Anastomosis: Novel Device for Clampless Proximal Vein Anastomosis in OPCAB Surgery--The Initial Spyder Experience." Heart Surgery Forum 8, no. 6 (2005): E443—E446. http://dx.doi.org/10.1532/hsf98.20041161.

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Tuyttens, F. A. M., D. W. Macdonald, and A. W. Roddam. "Response to Delahay, Waldram, Mallinson, Spyvee, Handoll, de Leeuw and Cheeseman." Journal of Zoology 260, no. 2 (2003): 120–21. http://dx.doi.org/10.1017/s0952836903233562.

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Di Benedetto, Roberta, Francesca Mancini, Martina Carducci, et al. "Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus." International Journal of Molecular Sciences 21, no. 22 (2020): 8558. http://dx.doi.org/10.3390/ijms21228558.

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No commercial vaccine is yet available against Group A Streptococcus (GAS), major cause of pharyngitis and impetigo, with a high frequency of serious sequelae in low- and middle-income countries. Group A Carbohydrate (GAC), conjugated to an appropriate carrier protein, has been proposed as an attractive vaccine candidate. Here, we explored the possibility to use GAS Streptolysin O (SLO), SpyCEP and SpyAD protein antigens with dual role of antigen and carrier, to enhance the efficacy of the final vaccine and reduce its complexity. All protein antigens resulted good carrier for GAC, inducing sim
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Guajardo, Nadia, Fernando A. Crespo, and Rodrigo A. Schrebler. "Simulation of the Reactivation of Partially Inactivated Biocatalysts in Sequential Batch Reactors." Processes 8, no. 11 (2020): 1419. http://dx.doi.org/10.3390/pr8111419.

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The enzymatic reactivation process enables the recovery of catalytic activity for inactive biocatalysts. However, its effect on the specific productivity of the processes has not been studied. The main objective of this work was to evaluate the specific productivity of the processes with and without reactivation using the program Spyder Python (3.7). Using fixed values for all of the parameters, the global specific productivity was 8 mM/h·gbiocat for the process without reactivation, and 4 mM/h·gbiocat for the process with reactivation. Random numbers were generated to use as different values
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30

Thomas, Matthew C., Dallas K. Thomas, L. Brent Selinger, and G. Douglas Inglis. "spyder, a new method for in silico design and assessment of 16S rRNA gene primers for molecular microbial ecology." FEMS Microbiology Letters 320, no. 2 (2011): 152–59. http://dx.doi.org/10.1111/j.1574-6968.2011.02302.x.

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31

Johnson, Kent D., and William Vantrease. "Does a Push-Up Using the Spyder 360 ™ Elicit More Muscle Activation Compared with a Standard Push-up?" Medicine & Science in Sports & Exercise 50, no. 5S (2018): 411. http://dx.doi.org/10.1249/01.mss.0000536438.73463.e4.

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32

Krupp, Ralf E. "Response to the Reply by N. F. Spycher and M. H. Reed." Geochimica et Cosmochimica Acta 54, no. 11 (1990): 3245. http://dx.doi.org/10.1016/0016-7037(90)90139-c.

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Turner, Claire E., Prathiba Kurupati, Michael D. Jones, Robert J. Edwards, and Shiranee Sriskandan. "Emerging Role of the Interleukin‐8 Cleaving Enzyme SpyCEP in ClinicalStreptococcus pyogenesInfection." Journal of Infectious Diseases 200, no. 4 (2009): 555–63. http://dx.doi.org/10.1086/603541.

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Rifa’i, Ahmad, Galet Guntoro Setiaji, and Vensy Vydia. "PENGGUNAAN METODE K-MEANS PADA ANALISA DAN KLASIFIKASI CAPRES 2019 DI TWITTER." Jurnal Pengembangan Rekayasa dan Teknologi 15, no. 1 (2019): 43. http://dx.doi.org/10.26623/jprt.v15i1.1489.

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<p>Media sosial merupakan wadah untuk mencurahkan kata-kata melalui tulisan pada dunia maya (<em>online)</em>, sehingga pada nantinya akan dapat dilihat oleh banyak orang baik yang dikenal maupun tidak dikenal. Twitter merupakan jejaring sosial atau media sosial yang memiliki teks terbatas, yaitu memiliki Panjang teks sebanyak 280 karakter. Metode crawling merupakan metode yag digunakan untuk pengambilan data dari media sosial yang dapat digunakan sebagai <em>developer application.</em></p><p><em>Crawling </em>data pada media sosial twitter
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Et. al., Lijetha C. Jaffrin,. "Applying Ensemble Learning Algorithm in Early Prognosis of Heart Illness." Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, no. 2 (2021): 1769–74. http://dx.doi.org/10.17762/turcomat.v12i2.1513.

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Medical diagnosis and treatment of diseases are the key elements of machine learning algorithms nowadays. To find similarities between various diseases, machine learning algorithms are used. Many people are now dying due to sudden heart attacks. Predicting and diagnosing heart disease is a daunting aspect faced by physicians and hospitals around the world. There is a need to foreknow whether or not a person is at risk of heart syndrome in advance, in order to minimize the number of deaths due to heart disease. In this field, machine learning algorithms play a very significant role. Many resear
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Beaudhuin, M., K. Zaidat, T. Duffar, and M. Lemiti. "Silicon purity controlled under electromagnetic levitation (SPYCE): influences on undercooling." Journal of Materials Science 45, no. 8 (2009): 2218–22. http://dx.doi.org/10.1007/s10853-009-4011-9.

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Zingaretti, Chiara, Fabiana Falugi, Vincenzo Nardi‐Dei, et al. "Streptococcus pyogenes SpyCEP: a chemokine‐inactivating protease with unique structural and biochemical features." FASEB Journal 24, no. 8 (2010): 2839–48. http://dx.doi.org/10.1096/fj.09-145631.

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Kaur, Simran Jeet, Andreas Nerlich, Simone Bergmann, et al. "The CXC Chemokine-degrading Protease SpyCep ofStreptococcus pyogenesPromotes Its Uptake into Endothelial Cells." Journal of Biological Chemistry 285, no. 36 (2010): 27798–805. http://dx.doi.org/10.1074/jbc.m109.098053.

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39

Alarcon, Andrea. "Book review essay on Nell Haynes, Social Media in Northern Chile and Juliano Spyer, Social Media in Emergent Brazil." Tapuya: Latin American Science, Technology and Society 3, no. 1 (2020): 165–69. http://dx.doi.org/10.1080/25729861.2020.1780696.

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Prihatiningsih, Siwi, Nadhiranisa Shafiy M, Feni Andriani, and Nurma Nugraha. "ANALISA PERFORMA PENGENALAN TULISAN TANGAN ANGKA BERDASARKAN JUMLAH ITERASI MENGGUNAKAN METODE CONVOLUTIONAL NEURAL NETWORK." Jurnal Ilmiah Teknologi dan Rekayasa 24, no. 1 (2019): 58–66. http://dx.doi.org/10.35760/tr.2019.v24i1.1934.

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Pada zaman modern ini teknologi informasi khususnya bidang Artificial Intelligence berkembang pesat dari waktu ke waktu. Hal ini mendorong manusia berkreasi untuk menciptakan teknologi baru untuk mempermudah orang dalam mengakses informasi yang diinginkan dengan cepat. Salah satu metode Artificial Intelligence yang cukup dikenal adalah Convolutional Neural Network. Namun, masih terdapat permasalahan terkait cara yang tepat yang dapat membuat performa lebih baik. Pada penelitian ini dilakukan analisa performa pengenalan tulisan tangan angka berdasarkan perubahan jumlah iterasi menggunakan metod
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Abdel-Shafi, Al-Mohammadi, Hamdi, Moustafa, and Enan. "Biological Characterization and Inhibition of Streptococcus pyogenes ZUH1 Causing Chronic Cystitis by Crocus sativus Methanol Extract, Bee Honey Alone or in Combination with Antibiotics: An In Vitro Study." Molecules 24, no. 16 (2019): 2903. http://dx.doi.org/10.3390/molecules24162903.

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Streptococcus pyogenes (S. pyogenes) ZUH1 was isolated and characterized using morphological, cultural and biochemical methods. The results showed that the marker genes (namely spyCEP, ssa, sic, sdaB and speG) indicating group A streptococci (GAS) were detected in the S. pyogenes genome. The results showed that the S. pyogenes strain was inhibited by Crocus sativus methanol extract (CSME), bee honey (BH) and catfish glycoprotein (CFG). The inhibitory activity of these natural agents were compared with standard antibiotics such as Ceftazidime (30 μg/mL), Cefoperazone (75 μg/mL), Cefoxitin (30 μ
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Goldblatt, Jennifer, Richard Ashley Lawrenson, Luke Muir, et al. "A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP." Journal of Immunology 202, no. 11 (2019): 3246–55. http://dx.doi.org/10.4049/jimmunol.1801688.

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43

Zinkernagel, Annelies S., Anjuli M. Timmer, Morgan A. Pence, et al. "The IL-8 Protease SpyCEP/ScpC of Group A Streptococcus Promotes Resistance to Neutrophil Killing." Cell Host & Microbe 4, no. 2 (2008): 170–78. http://dx.doi.org/10.1016/j.chom.2008.07.002.

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Chiappini, Nico, Anja Seubert, John L. Telford, et al. "Streptococcus pyogenes SpyCEP Influences Host-Pathogen Interactions during Infection in a Murine Air Pouch Model." PLoS ONE 7, no. 7 (2012): e40411. http://dx.doi.org/10.1371/journal.pone.0040411.

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45

Ehlers, V. J., M. J. Oosthuizen, M. C. Bezuidenhout, L. V. Monareng, and K. Jooste. "Post-basic nursing students’ perceptions of the emigration of nurses from the republic of South Africa." Health SA Gesondheid 8, no. 4 (2003): 24–37. http://dx.doi.org/10.4102/hsag.v8i4.143.

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The emigration of nurses from South Africa to work in overseas countries continues to increase despite efforts to curb this phenomenon.
 
 Opsomming
 Die emigrasie van Suid-Afrikaanse verpleegkundiges om in oorsese lande te werk neem toe ten spyte van pogings om die verskynsel te bekamp.
 
 *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
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46

Shaw, Helen A., James Ozanne, Keira Burns, and Fatme Mawas. "Multicomponent Vaccines against Group A Streptococcus Can Effectively Target Broad Disease Presentations." Vaccines 9, no. 9 (2021): 1025. http://dx.doi.org/10.3390/vaccines9091025.

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Group A Streptococcus (GAS) is an important global human pathogen, with a wide range of disease presentations, from mild mucosal infections like pharyngitis to invasive diseases such as toxic shock syndrome. The effect on health and mortality from GAS infections is substantial worldwide, particularly from autoimmune sequelae-like rheumatic heart disease (RHD), and there is currently no licenced vaccine. We investigated protein antigens targeting a broad range of GAS disease presentations as vaccine components in individual and combination formulations. The potency and functional immunity gener
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47

Theron, Linda, Stephan Geyer, Herman Strydom, and CSL Delport. "The roots of reds: a rationale for the support of educators affected by the HIV and aids pandemic." Health SA Gesondheid 13, no. 4 (2008): 77–88. http://dx.doi.org/10.4102/hsag.v13i4.406.

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The nature of educators’ work has changed dramatically, in part because of the challenges of the HIV and AIDS pandemic. Despite these multiple and relentless challenges which educators contend with, and despite numerous calls for educator empowerment to cope with HIV -related challenges, little has been done up until now to support educators. By reviewing current literature, this article outlines the HIV-altered professional reality of South African educators and makes the argument that affected educators need support to cope. In conclusion, the support programme, Resilient Educators (REds), i
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48

Singh, N., H. Zghal, N. Sepehri, S. Balakrishnan, and P. D. Lawrence. "Coordinated-motion control of heavy-duty industrial machines with redundancy." Robotica 13, no. 6 (1995): 623–33. http://dx.doi.org/10.1017/s0263574700018713.

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SummaryAn implementation of a real-time scheme suitable for coordinated-motion control of a class of teleoperated industrial machines with redundancy is presented. An efficient gradient projection technique is adopted for the numerical solution. The scheme utilizes the redundancy to avoid the joint limits by minimizing a hyperbolic function of the joint distances from the mid-range. This new performance criterion is shown to be advantageous over similar criteria; both the joint-limit avoidance capability and the resulting joint velocity profiles can be adjusted by the appropriate choice of par
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49

Nwaneri, S. C., J. O. Ezeagbor, D. O. T. Orunsholu, and C. O. Anyaeche. "Optimisation of Patient Flow and Scheduling in an Outpatient Haemodialysis Clinic." Nigerian Journal of Technological Development 18, no. 2 (2021): 119–28. http://dx.doi.org/10.4314/njtd.v18i2.6.

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The demand for renal replacement therapy (RRT) from the growing number of patients suffering from chronic kidney disease (CKD) and end stage renal disease (ESRD) in Nigeria is reported to be on the rise. However, dialysis clinics are few with limited facilities to meet the increasing demand leading to congestion, long waiting time and increased length of stay (LOS) in dialysis clinics. This paper presents an optimisation model for scheduling patient flow in an outpatient haemodialysis clinic. The objective is to minimize patient LOS using Genetic Algorithm (GA), implemented in Python programmi
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50

Chuvashova, Maria, Gleb Druzhinin, and Alena Gorbacheva. "Determination of the development level of information and telecommunication networks within the regions of Siberian Federal District." E3S Web of Conferences 295 (2021): 01054. http://dx.doi.org/10.1051/e3sconf/202129501054.

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According to the scientific papers of the Russian scientists, the parameters for assessing the quality of economic space are population density, spatial connectivity and location of production. The parameter of the spatial connectivity is considered. In most of the Russian scientific papers, the term “the spatial connectivity” is determined by the level of transport networks development. In most Russian scientific papers when forming models for assessing the spatial connectivity of regions, the issue of territorial connectivity by information and telecommunication networks is not investigated.
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