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1

Ateş, İhsan, Ozan Yazıcı, Hale Ateş, et al. "Squamous Cell Cancer of The Lung with Synchronous Renal Cell Carcinoma." Turkish Thoracic Journal 17, no. 3 (2016): 125–27. http://dx.doi.org/10.5578/ttj.30510.

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2

Garrepalli, Saritha. "Global Patterns of Lung Cancer Incidence." Cancer Research and Cellular Therapeutics 2, no. 2 (2018): 01–03. http://dx.doi.org/10.31579/2640-1053/027.

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Introduction It is well known that smoking is injurious to health which causes lung cancer. Although not all smokers develop lung cancer, fraction of lifelong non-smokers will die from lung cancer. Lung cancer is a major cause of cancer related death in developed countries with extremely poor overall survival rate. In present study we set out epidemiological pattern with clinical profile of lung cancer patients in northern india population. Aim:We evaluate the effect of smoking with age distribution on histopathology in lung cancer patients. Material & Methods: We enrolled 218 patients aft
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3

Hashimoto, Atsushi, Yuichiro Kawasaki, Akito Tominaga, et al. "Squamous Cell Lung Cancer." JCR: Journal of Clinical Rheumatology 26, no. 5 (2019): e137-e137. http://dx.doi.org/10.1097/rhu.0000000000001010.

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4

Mitri, Maria, and Samer F. Nehme. "Rapid killer: Lung squamous cell cancer." Discussion of Clinical Cases 8, no. 2 (2021): 11. http://dx.doi.org/10.5430/dcc.v8n2p11.

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Background: Lung cancer is one of the leading causes of death despite improvement in treatment modalities such as immunotherapy with chemotherapy and precise radiotherapy. NSCLC is a heterogeneous group of diseases that differs in cytology and includes adenocarcinoma, squamous cell carcinoma, bronchioloalveolar carcinoma, and poorly differentiated carcinoma. Usually, NSCLC, in contrast to SCLC, spreads locally, and the doubling time of squamous cell carcinoma is 133 days which classifies it as a relatively slow-growing tumor.Case presentation: We present the case of a 72-year-old male, recentl
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5

Ayman, Rasmy, Ameen Amal, and AbdMonem Amira. "Lung Cancer Treatment: Incidence and Survival: SEER Database." Cancer Medicine Journal 2, no. 2 (2019): 36–40. http://dx.doi.org/10.46619/cmj.2019.2-1011.

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Lung cancer is the most common cause of cancer death worldwide, with an estimated 1.6 million deaths each year. Nearly 85% of cases have a different histological groups jointly recognized as “Non-Small Cell Lung Cancer of which lung adenocarcinoma and lung squamous cell carcinoma are the most common subtypes”.
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6

Brinkmeyer, Jessica K., and Donald C. Moore. "Necitumumab for the treatment of squamous cell non-small cell lung cancer." Journal of Oncology Pharmacy Practice 24, no. 1 (2016): 37–41. http://dx.doi.org/10.1177/1078155216682365.

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Non-small cell lung cancer is the most common form of lung cancer, accounting for about 85% of all cases and is further subdivided into adenocarcinoma, squamous cell, and large cell carcinoma. Necitumumab (Portrazza™, Eli Lilly and Company) is an anti-epidermal growth factor receptor monoclonal antibody approved for the first-line treatment of squamous cell non-small cell lung cancer in combination with cisplatin and gemcitabine. The safety and efficacy of necitumumab has been evaluated in two-phase III clinical trials, one demonstrating a lack of efficacy in non-squamous non-small cell lung c
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7

Villanueva, M. Teresa. "Squamous cell lung cancer changes driver." Nature Reviews Drug Discovery 20, no. 3 (2021): 177. http://dx.doi.org/10.1038/d41573-021-00028-4.

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8

Rooney, Melissa, Siddhartha Devarakonda, and Ramaswamy Govindan. "Genomics of Squamous Cell Lung Cancer." Oncologist 18, no. 6 (2013): 707–16. http://dx.doi.org/10.1634/theoncologist.2013-0063.

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9

Lai, C. C., C. K. Tan, and J. Y. Shih. "Acrometastasis from squamous cell lung cancer." Canadian Medical Association Journal 177, no. 3 (2007): 249. http://dx.doi.org/10.1503/cmaj.061525.

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10

Khan, Raza Anwar. "Incidence of squamous cell lung cancer." Journal of Clinical Oncology 32, no. 15_suppl (2014): e19128-e19128. http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e19128.

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11

Shyu, Ching-Lih, Yu-Chin Lee, and Reury-Perng Perng. "Fast-growing squamous cell lung cancer." Lung Cancer 36, no. 2 (2002): 199–202. http://dx.doi.org/10.1016/s0169-5002(02)00007-7.

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12

Pasic, A., E. F. Comans, M. A. Paul, P. E. Postmus, and T. G. Sutedja. "Borderline early squamous cell lung cancer." Breathe 1, no. 2 (2004): 157–59. http://dx.doi.org/10.1183/18106838.0102.157.

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13

Wulandari, Laksmi, and Nikson Eduard Faot. "Problem Penegakkan Diagnostik Pasien dengan Massa di Paru." Jurnal Respirasi 3, no. 2 (2019): 41. http://dx.doi.org/10.20473/jr.v3-i.2.2017.41-46.

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Background: Lung cancer are divided into 2 groups; i.e. Small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). About 30% of NSCLC is squamus cell carcinoma and the other is adeno carcinoma. Late diagnosis makes such a high mortality rate. Early diagnosis plays a very important role in the management of therapy. Case: Patients complain of chronic cough more than 6 months, decreased appetite and weight loss. Chest X-ray and CT scan show a density of round shape mass, with firm border and smooth regular edge, also lympnodes enlargement (T2N2Mx) stage IIb. Appearance of lung mass is
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14

Tacha, David, Ryan Bremer, Thomas Haas, and Weiman Qi. "An Immunohistochemical Analysis of a Newly Developed, Mouse Monoclonal p40 (BC28) Antibody in Lung, Bladder, Skin, Breast, Prostate, and Head and Neck Cancers." Archives of Pathology & Laboratory Medicine 138, no. 10 (2014): 1358–64. http://dx.doi.org/10.5858/arpa.2013-0342-oa.

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Context.—Immunohistochemistry is important to the pathologist for accurate diagnosis of lung cancer. In recent studies, a rabbit polyclonal p40 (RPp40) antibody demonstrated equivalent staining versus anti-p63 in lung squamous cell carcinoma, and superior specificity because it stains a lesser percentage of lung adenocarcinoma. Objectives.—To develop an anti-p40 mouse monoclonal antibody (MMp40) for immunohistochemistry, and to evaluate its sensitivity and specificity in normal and neoplastic tissues, with emphasis on lung cancer. Design.—The MMp40 (BC28) antibody was developed and tested for
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15

Prat, Aleix, Barbara Adamo, Cheng Fan, et al. "Molecular identification of basal-like breast cancer through genomic analyses across five cancer types." Journal of Clinical Oncology 31, no. 15_suppl (2013): 1011. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.1011.

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1011 Background: Common molecular alterations in different types of cancer are being identified and these might be successfully targeted regardless of the tumor´s tissue of origin. To better understand the genomic relationships among different types of cancer, we explored global gene expression patterns across breast, lung, ovarian, brain and colorectal cancers. Methods: A unified set of 1,707 samples of 5 human cancer types (breast [n=547], lung [squamous and adenocarcinomas, n=249], ovarian [serous carcinoma, n=489], brain [glioblastoma multiforme, n=202] and colorectal [n=220]) from The Can
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16

Tadokoro, Akira, Nobuhiro Kanaji, Tomoya Ishii, et al. "Transbronchial Dissemination of Squamous Cell Lung Cancer." Clinical Medicine Insights: Oncology 9 (January 2015): CMO.S32707. http://dx.doi.org/10.4137/cmo.s32707.

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We report a case of squamous cell lung cancer with transbronchial dissemination in a 73-year-old man. Bronchoscopic examination revealed multiple bronchial mucosal nodules that existed independently of one another. We reviewed 16 previous cases of endobronchial metastasis in lung cancer. All patients were men. Among the reports that described the smoking history, most patients were smokers (6/7), and the most frequent histological type of cancer was squamous cell carcinoma (11/17). Although hematogenous and lymphogenous routes have been reported as metastatic mechanisms, no previous cases invo
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17

Shi, Ivy, Nooshin Hashemi Sadraei, Zhong-Hui Duan, and Ting Shi. "Aberrant Signaling Pathways in Squamous Cell Lung Carcinoma." Cancer Informatics 10 (January 2011): CIN.S8283. http://dx.doi.org/10.4137/cin.s8283.

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Lung cancer is the second most commonly occurring non-cutaneous cancer in the United States with the highest mortality rate among both men and women. In this study, we utilized three lung cancer microarray datasets generated by previous researchers to identify differentially expressed genes, altered signaling pathways, and assess the involvement of Hedgehog (Hh) pathway. The three datasets contain the expression levels of tens of thousands genes in normal lung tissues and squamous cell lung carcinoma. The datasets were combined and analyzed. The dysregulated genes and altered signaling pathway
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18

Chen, Mai-Lin, Xiao-Ting Li, Yi-Yuan Wei, Li-Ping Qi, and Ying-Shi Sun. "Diagnostic Value of Spectral CT Parameters in Differentiating Different Types of Lung Cancer." Journal of Medical Imaging and Health Informatics 10, no. 8 (2020): 1804–8. http://dx.doi.org/10.1166/jmihi.2020.3189.

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Background: This study proposed to quantitatively assess the value of spectral CT imaging parameters in differentiating different pathological types of lung cancer. Methods: Eighty five patients with lung cancer (66 non-mucinous adenocarcinomas, 7 Squamous cell carcinomas, 8 small cell carcinomas, 1 mucinous adenocarcinoma, 1 sarcomatoid carcinoma, 1 carcinoid, 1 large cell carcinoma) underwent CT plain scan, contrast enhanced CT scans in arterial phase (a) and venous phase (v) with spectral imaging mode on a GE Revolution Xtream CT scanner. The Spectral CT Imaging parameters: Iodine concentra
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19

Kawaguchi, Tomoya, Masaaki Kawahara, Yuji Kawaguchi, and Kiyoyuki Furuse. "Roentgenographically Occult Small-Cell Lung Cancer after Resection of Squamous Cell Lung Cancer." Journal of Bronchology 5, no. 1 (1998): 50–52. http://dx.doi.org/10.1097/00128594-199801000-00013.

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20

Medenica, Milic, Miras Medenica, Olivera Bojovic, Ivan Soldatovic, and Ivana Durutovic. "Changing trends in incidence of lung cancer by histological type in Montenegro." Srpski arhiv za celokupno lekarstvo 142, no. 1-2 (2014): 23–28. http://dx.doi.org/10.2298/sarh1402023m.

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Introduction. Lung cancer is one of the most common malignant neoplasms, as well as the most common cause of death cancer. Most lung cancers are squamous cell carcinomas, small cell carcinomas or adenocarcinomas. Objective. Examining changes in trends of lung cancer incidence in Montenegro by histological type during a 15-year period, from 1997 to 2011. Methods. During the study period, histopathological confirmation was obtained for all primary lung cancer cases in the only hospital for lung diseases in the country. Based on the data from medical records, patients were classified by time peri
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21

Liao, Rachel G., Hideo Watanabe, Matthew Meyerson, and Peter S. Hammerman. "Targeted therapy for squamous cell lung cancer." Lung Cancer Management 1, no. 4 (2012): 293–300. http://dx.doi.org/10.2217/lmt.12.40.

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22

Kim, Cheol Hyeon. "Druggable Targets of Squamous Cell Lung Cancer." Tuberculosis and Respiratory Diseases 75, no. 6 (2013): 231. http://dx.doi.org/10.4046/trd.2013.75.6.231.

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23

Koleczko, Sophia, Axel Hillmer, Abdel Hakim Bayarassou, et al. "KEAP1 mutations in squamous cell lung cancer." Journal of Clinical Oncology 39, no. 15_suppl (2021): e21098-e21098. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e21098.

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e21098 Background: KEAP1 mutations have been shown to decrease the efficacy of both chemotherapy (CTX) and immune-checkpoint inhibition (ICI) in lung adenocarcinoma. However, few is known about their impact on systemic treatment of squamous cell lung cancer (SqCC). The aim of this study was to assess the impact of KEAP1 mutations on systemic treatment outcome in SqCC. Methods: Tumor biopsies of SqCC patients were analyzed within the German Network Genomic Medicine (NGM) using a next-generation DNA sequencing (NGS) panel comprising 17 genes. In subsets, PD-L1 expression was tested with immunohi
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24

Choi, Sun Mi, Heounjeong Go, Doo Hyun Chung, and Jae-Joon Yim. "Spontaneous Regression of Squamous Cell Lung Cancer." American Journal of Respiratory and Critical Care Medicine 188, no. 4 (2013): e5-e6. http://dx.doi.org/10.1164/rccm.201208-1417im.

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25

Hammerman, Peter S. "Abstract IA39: Squamous cell lung cancer 2014." Clinical Cancer Research 20, no. 2 Supplement (2014): IA39. http://dx.doi.org/10.1158/1078-0432.14aacriaslc-ia39.

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26

Stewart, P. A., R. J. C. Slebos, E. A. Welsh, et al. "Proteogenomic Landscape of Squamous Cell Lung Cancer." Journal of Thoracic Oncology 12, no. 8 (2017): S1540. http://dx.doi.org/10.1016/j.jtho.2017.06.037.

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27

Cheng, Haiying, Marina Shcherba, Karthikeya Kandavelou, Yuanxin Liang, Huijie Liu, and Roman Perez-Soler. "Emerging drugs for squamous cell lung cancer." Expert Opinion on Emerging Drugs 20, no. 1 (2015): 149–60. http://dx.doi.org/10.1517/14728214.2015.1001365.

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28

Sutedja, T., and P. Postmus. "Photodynamic therapy in squamous cell lung cancer." European Journal of Cancer 29 (January 1993): S212. http://dx.doi.org/10.1016/0959-8049(93)91808-x.

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29

Goldstein, Daniel A., Qiushi Chen, Turgay Ayer, et al. "Necitumumab in Metastatic Squamous Cell Lung Cancer." JAMA Oncology 1, no. 9 (2015): 1293. http://dx.doi.org/10.1001/jamaoncol.2015.3316.

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30

Ma, Jinqi, and Fengxia Liu. "Study of tRNA-Derived Fragment tRF-20-S998LO9D in Pan-Cancer." Disease Markers 2022 (May 5, 2022): 1–9. http://dx.doi.org/10.1155/2022/8799319.

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Objective. The purpose is to study the effect of tRNA-derived fragments (tRFs) on pan-cancer through bioinformatics. Methods. The expression information of tRF-20-S998LO9D, a type of tRF-5, was retrieved through MINTbase in pan-cancer and verified by qPCR. We preliminarily explored the effect of tRF-20-S998LO9D on cell proliferation in breast cancer and lung cancer cell lines. Then an online KM-plotter provided by OncotRF was used to discover the prognostic significance. GO/KEGG analyses were executed to predict the potential mechanism of tRF-20-S998LO9D in cancer. Results. We found that tRF-2
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31

Cagle, Philip T., Qihui “Jim” Zhai, Linda Murphy, and Philip S. Low. "Folate Receptor in Adenocarcinoma and Squamous Cell Carcinoma of the Lung: Potential Target for Folate-Linked Therapeutic Agents." Archives of Pathology & Laboratory Medicine 137, no. 2 (2013): 241–44. http://dx.doi.org/10.5858/arpa.2012-0176-oa.

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Context.— Lung cancer is the number one cause of cancer deaths in the United States and globally. The advent of targeted therapies has offered a new treatment paradigm for lung cancer, but currently validated and emerging drugs are effective in only a small minority of lung cancers, predominantly adenocarcinomas. Folate receptors can serve as targets for drugs attached to folate and are overexpressed in many cancers. Objective.— To determine the frequency of folate receptor overexpression in lung cancers of different cell types as potential targets for folate-linked therapy. Design.— High-dens
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32

Wang, Jiahui, Qiuru Zhou, Cihui Yan, et al. "Dysregulated Th1 cells in lung squamous cell carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e20566-e20566. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e20566.

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e20566 Background: Lung squamous cell carcinoma (LUSC) is one of the most common subtypes of lung cancer which lacks of effective treatments compared to lung adenocarcinoma. The Th1 subset in CD4+ T cells plays an indispensable role in antitumor immune responses. However, there are few studies on Th1 cells in LUSC. Methods: Firstly, we used single-cell RNA-seq to analyze the gene expression in 8 LUSC patients’ tissues, including tumor tissues, paracancerous tissues, normal tissues, lymphoid tissues, pre-treatment blood samples and pre-operative blood samples. A total of qualified 44969 CD4+ T
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33

Wang, Jiahui, Qiuru Zhou, Cihui Yan, et al. "Dysregulated Th1 cells in lung squamous cell carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e20566-e20566. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e20566.

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e20566 Background: Lung squamous cell carcinoma (LUSC) is one of the most common subtypes of lung cancer which lacks of effective treatments compared to lung adenocarcinoma. The Th1 subset in CD4+ T cells plays an indispensable role in antitumor immune responses. However, there are few studies on Th1 cells in LUSC. Methods: Firstly, we used single-cell RNA-seq to analyze the gene expression in 8 LUSC patients’ tissues, including tumor tissues, paracancerous tissues, normal tissues, lymphoid tissues, pre-treatment blood samples and pre-operative blood samples. A total of qualified 44969 CD4+ T
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34

Shopov, Spasimir. "Endobronchial localization - arena of two tumors: a case report." Folia Medica 64, no. 6 (2022): 1003–6. http://dx.doi.org/10.3897/folmed.64.e71252.

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The lung is a common arena for metastases of tumors with different localization, but endobronchial localization of metastases is very rare. The most common tumors with endobronchial localization of metastasis are renal, breast, and colorectal cancer. We report a man presenting with cough and hemoptysis. Endobronchial biopsy showed renal cell carcinoma and micro-invasive bronchogenic squamous cell carcinoma. Endobronchial metastases from renal cell carcinoma are rare. The squamous cell lung cancer is one of the most common cancers in men, but the combination of renal cell carcinoma and micro-in
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35

Szturmowicz, M., A. Sakowicz, P. Rudzinski, et al. "The Clinical Value of Cyfra 21-1 Estimation for Lung Cancer Patients." International Journal of Biological Markers 11, no. 3 (1996): 172–77. http://dx.doi.org/10.1177/172460089601100306.

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Cytokeratin-19, one of the cytoskeletal proteins, is expressed both in bronchial epithelium and in lung cancer cells. The aim of our study was to establish the value of serum cytokeratin-19 soluble fragment (Cyfra 21-1) measurement in lung cancer patients. Cyfra 21-1 levels were estimated in 35 patients (pts) with benign lung diseases and in 116 lung cancer patients: 55 pts with squamous cell lung cancer, 38 pts with small cell lung cancer and 23 pts with adenocarcinoma. The cutoff level was set at 4 ng/ml with a specificity of 94% and a sensitivity of 40%. Elevated Cyfra 21-1 values were foun
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36

Sato, Seijiro, Terumoto Koike, Takehisa Hashimoto, and Masanori Tsuchida. "Surgical Resection for a Second Primary Lung Cancer Originating Close to the Initial Surgical Margin for Lung Squamous Cell Carcinoma." Case Reports in Surgery 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/462193.

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Few reports have described surgical resection for second primary lung cancers originating close to the initial surgical margin for lung cancer. A 64-year-old man had undergone left segmentectomy with lymph node dissection for small peripheral squamous cell lung cancer using video-assisted thoracic surgery, with pathology confirming a small tumor 12 mm in diameter identified about 3 cm from the surgical margin. Eighteen months after initial surgery, computed tomography revealed a 30 mm pulmonary nodule close to the initial surgical margin in the residual left upper lobe and the serum level of c
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37

Jiwani, Rahim, Heather Brody, Yuxuan Mao, et al. "193 Differences in thyroid immune-related adverse events between lung cancer types, a retrospective analysis." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A208. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0193.

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BackgroundImmune modulation of the PD-1/PD-L1 pathway is a promising treatment of various malignancies however, alteration of the pathway is known to cause many immune related adverse events (irAEs) including thyroid dysfunction. Whether the frequency of thyroid irAEs differ between lung cancer types has not yet been studied.MethodsA total of three hundred twenty-nine lung cancer patients treated with immunotherapy at East Carolina University between April 2014 and July 2019 were included in a retrospective cohort analysis. Baseline TSH and TSH at each treatment cycle were recorded along with
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38

Lu, Tao, Xinglan Li, and Yao Zhou. "Pancreatic metastasis from squamous cell lung cancer: computed tomography and magnetic resonance imaging findings." Journal of International Medical Research 49, no. 2 (2021): 030006052199618. http://dx.doi.org/10.1177/0300060521996188.

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Metastatic lesions of the pancreas are uncommon. The incidence of pancreatic involvement with squamous cell carcinoma is the lowest among the different histological subtypes of lung cancer. We present the clinical data, pathological findings, and imaging features of two cases of pancreatic metastasis from squamous cell lung cancer with a literature review. A 75-year-old man and a 67-year-old man were both diagnosed with metastatic pancreatic tumors from squamous cell lung cancer during a multidisciplinary team discussion. Both patients were misdiagnosed as having a neuroendocrine tumor of the
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39

Win, Aung Zaw, and Carina Mari Aparici. "A Case of Metastatic Rectal Squamous Cell Carcinoma Initially Diagnosed as Lung Cancer." Journal of Clinical Imaging Science 5 (April 30, 2015): 22. http://dx.doi.org/10.4103/2156-7514.156125.

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Squamous cell carcinoma (SCC) of the rectum is extremely rare with a reported incidence of only 0.025–0.1% of all colorectal tumors. The patient was a 68-year-old man who presented with fatigue, dry cough, shortness of breath, and unintentional weight loss. A chest CT revealed a left suprahilar mass suspected to be lung cancer and an initial diagnosis of primary lung cancer was made. However, fluorodeoxyglucose positron emission tomography and computed tomography (FDG-PET/CT) exam revealed an intensely hypermetabolic rectal mass which turned out to be rectal squamous cell carcinoma. This is th
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40

Yaqub, Farhat. "Nivolumab for squamous-cell non-small-cell lung cancer." Lancet Oncology 16, no. 7 (2015): e319. http://dx.doi.org/10.1016/s1470-2045(15)00033-9.

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41

Chaturvedi, Anil K., Ruth A. Kleinerman, Allan Hildesheim, et al. "Second Cancers After Squamous Cell Carcinoma and Adenocarcinoma of the Cervix." Journal of Clinical Oncology 27, no. 6 (2009): 967–73. http://dx.doi.org/10.1200/jco.2008.18.4549.

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Purpose Although cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) are both caused by human papillomavirus (HPV) infection, they differ in cofactors such as cigarette smoking. We assessed whether these cofactor differences translate into differences in second cancer risk. Patients and Methods We assessed second cancer risk among 85,109 cervical SCC and 10,280 AC survivors reported to population-based cancer registries in Denmark, Finland, Norway, Sweden, and the United States. Risks compared to the general population were assessed using standardized incidence ratios (SIR). Results
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42

Jain, M. "AN OVERVIEW ON “CELLULAR CANNIBALISM” WITH SPECIAL REFERENCE TO ORAL SQUAMOUS CELL CARCINOMA." Experimental Oncology 37, no. 4 (2015): 242–45. http://dx.doi.org/10.31768/2312-8852.2015.37(4):242-245.

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Cellular cannibalism has been defined as a large cell engulfing a slightly smaller one within its cytoplasm. It has been described in various cancers like bladder cancer, breast cancer, lung cancer, gastric cancer, oral squamous cell carcinoma. Cellular cannibalism has been well correlated with anaplasia, tumor aggressiveness, grading and metastatic potential. Present review focuses on significance of cannibalism in relation to cancer with special emphasis on oral squamous cell carcinoma.
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43

Barclay, Matthew E., Georgios Lyratzopoulos, Fiona M. Walter, Sarah Jefferies, Michael D. Peake, and Robert C. Rintoul. "Incidence of second and higher order smoking-related primary cancers following lung cancer: a population-based cohort study." Thorax 74, no. 5 (2019): 466–72. http://dx.doi.org/10.1136/thoraxjnl-2018-212456.

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BackgroundLung cancer 5-year survival has doubled over 15 years. Although the risk of second primary cancer is recognised, quantification over time is lacking. We describe the incidence of second and higher order smoking-related primary cancers in lung cancer survivors, identifying high-incidence groups and how incidence changes over time from first diagnosis.MethodsData on smoking-related primary cancers (lung, laryngeal, head and neck, oesophageal squamous cell carcinoma and bladder) diagnosed in England between 2000 and 2014 were obtained from Public Health England National Cancer Registrat
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44

Shrestha, H. G. "Lung Cancer in Nepal - Histological Typing And Its Relations With Smoking." Journal of Nepal Medical Association 26, no. 3 (2003): 1–8. http://dx.doi.org/10.31729/jnma.1616.

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Out of 51 bronchoscopy biopsy, thirty (60%) were of lung cancer which made 5.3% of the whole malignant tumours, i.e. 562 cancers in different sites in 26 months study in the Department of Pathology, TUTH. Squamous cell carcinoma (22 cases or 73.3%) was the commonest followed by Oat cell carcinoma (5 cases or 16.7%). Lung cancer was found more in the old age group, that is 23 cases (7.7%) in over 50 yrs old, 6 cases (20%) in 40-50 yrs group and only one case (3%) in 25 yrs male. The average age for the lung cancer in this study is 58.2 yrs. Lung cancer is more common in male than in female (5:1
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45

Fu, Shen-Shen, Yu-Zhen Zheng, Xian-Yu Qin, et al. "Establishing a prognostic model for metachronous second squamous cell lung cancer in patients with resected squamous cell lung cancer." Journal of Thoracic Disease 14, no. 1 (2022): 90–101. http://dx.doi.org/10.21037/jtd-21-1164.

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46

Gawełko, Jan, Marek Cierpiał-Wolan, Second Bwanakare, and Michalina Czarnota. "Association between Air Pollution and Squamous Cell Lung Cancer in South-Eastern Poland." International Journal of Environmental Research and Public Health 19, no. 18 (2022): 11598. http://dx.doi.org/10.3390/ijerph191811598.

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Air pollution is closely associated with the development of respiratory illness. The aim of the present study was to assess the relationship between long-term exposure to PM2.5, PM10, NO2, and SO2 pollution and the incidence of lung cancer in the squamous subtype in south-eastern Poland from the years 2004 to 2014. We collected data of 4237 patients with squamous cell lung cancer and the level of selected pollutants. To investigate the relationship between the level of concentrations of pollutants and the place of residence of patients with lung cancer in the squamous subtype, proprietary poll
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Schumacher, Udo, Dhia Mukthar, and Thomas Schenker. "Reactivity of Monoclonal Antibodies Directed against Lung Cancer Antigens with Human Lung, Breast and Colon Cancer Cell Lines." Disease Markers 11, no. 5-6 (1993): 225–37. http://dx.doi.org/10.1155/1993/619781.

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A panel of monoclonal antibodies (n=72 including controls) directed against lung cancer antigens was screened immunohistochemically against a panel of seven human lung cancer cell lines (including small cell carcinoma, squamous cell carcinoma, adenocarcinoma and mesothelioma), six human breast cancer cell lines and one human colon cancer cell line, The majority of the antibodies (n=42) reacted also with antigens present on breast and colon cancer cell lines, This cross reactivity especially between lung and breast cancer cell lines is not altogether unexpected since antigens common to breast a
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48

_, _. "Non–Small Cell Lung Cancer." Journal of the National Comprehensive Cancer Network 6, no. 3 (2008): 228. http://dx.doi.org/10.6004/jnccn.2008.0021.

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Lung cancer is the leading cause of cancer-related death in both men and women in the United States. An estimated 213,380 new cases (114,760 men and 98,620 women) of lung and bronchus cancer will be diagnosed in 2007, and 160,390 deaths (89,510 in men, 70,880 in women) are estimated to occur because of the disease. Non-small cell lung cancer (NSCLC) accounts for 80% to 85% of all lung cancer cases and includes 3 major types: (1) adenocarcinoma; (2) squamous cell (epidermoid) carcinoma; and (3) large-cell carcinoma. Adenocarcinoma is the most common type of lung cancer seen in the United States
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49

Gerber, David E., Paul K. Paik, and Afshin Dowlati. "Beyond Adenocarcinoma: Current Treatments and Future Directions for Squamous, Small Cell, and Rare Lung Cancer Histologies." American Society of Clinical Oncology Educational Book, no. 35 (May 2015): 147–62. http://dx.doi.org/10.14694/edbook_am.2015.35.147.

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Lung cancer encompasses a diverse spectrum of histologic subtypes. Until recently, the majority of therapeutic advances were limited to the minority of patients with adenocarcinoma. With the advent of comprehensive genomic profiling of squamous and small cell lung cancers, new therapeutic targets have emerged. For squamous tumors, the most promising of these include fibroblast growth factor receptor (FGFR), the phosphatidylinositol 3-kinase (PI3K) pathway, discoidin domain receptor 2 (DDR2), and G1/S checkpoint regulators. In 2014, the antiangiogenic agent ramucirumab was approved for all non–
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Chen, Hao, Liru Tian, Jiahong Chen, et al. "Evaluation of 2 Commercially Systems for Detection of Serum Squamous Cell Carcinoma Antigen in Pan Squamous Cell Carcinoma." Cancer Control 27, no. 1 (2020): 107327482098302. http://dx.doi.org/10.1177/1073274820983025.

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Background: This study compared the analytical performance of the Elecsys 602 (Roche Diagnostics) system with the I2000 (Abbott laboratories) system for the quantitative measurement of squamous cell carcinoma antigen (SCCA) to assess its role as an indicator in pan squamous cell carcinoma. Methods: 435 serum samples included pan squamous cell cancer group (n = 318) and healthy subjects (n = 52) and non-squamous cell group (n = 41) and benign diseases group (n = 24) were measured by 2 systems and compared. Results: The within-run precision coefficient of variation (CV) for Abbott and Roche syst
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