Relevant bibliographies by topics / SS Thalassemia minor

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Academic literature on the topic 'SS Thalassemia minor'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "SS Thalassemia minor"

1

Ashok, Kumar Kapoor* Sharmila Gupta Ashutosh Kumar Yamini Jindal Upama Singh. "CLINICO-PATHOLOGICAL CORRELATION OF SICKLE HEMOGLOBIN (HBS)." Indian Journal of Medical Research and Pharmaceutical Sciences 3, no. 11 (2016): 28–33. https://doi.org/10.5281/zenodo.167400.

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<strong>Introduction:</strong> Present study relates to the results of clinical examination of 10 patients with sickle hemoglobin. <strong>Material and Methods:</strong>All the patients belonged to TharuChaudhary community of Nepal. The patients were clinically examined. Sickling test was done using Sodium metasulphite. Hemoglobin agarose gel electrophoresis was done at alkaline pH. Total hemoglobin was estimated by cyanhemoglobin method. <strong>Results: </strong>Sickling test was positive in all the patients. In addition, electrophoresis revealed detection of HbS in all the patients. Four of
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2

Westhoff, Connie M., Marek Simm, Carl Myers, Stella T. Chou, Adonis Stassinopoulos, and Beth H. Shaz. "Donor Availability for Extended Phenotype Matching for Transfusion in Thalassemia and Sickle Cell Disease." Blood 120, no. 21 (2012): 2287. http://dx.doi.org/10.1182/blood.v120.21.2287.2287.

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Abstract Abstract 2287 High throughput genomic testing for blood groups allows large scale antigen typing and assessment of donor pool compatibility with chronic transfusion dependent populations, particularly thalassemia or sickle cell disease (SCD) patients, in order to decrease RBC alloimmunization. Thus, it is crucial to determine if the quantity and antigen diversity of the donor pool meets the demands to sustain these patients on phenotype/genotype extended matched chronic transfusion protocols. We calculated the most common extended RBC predicted phenotypes for the 12 major clinically s
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3

Sowa, Anna, Yue Hu, Mark T. Gladwin, et al. "Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Avascular Necrosis in Sickle Cell Disease." Blood 144, Supplement 1 (2024): 5297. https://doi.org/10.1182/blood-2024-207552.

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Background: Avascular necrosis (AVN) is a debilitating complication of sickle cell disease (SCD). The incidence of AVN in individuals with SCD is markedly higher than in the general population, affecting even young children and up to 30% of those over the age of 45. While candidate gene studies have explored genetic associations with AVN in SCD, no genome-wide association studies (GWAS) have been conducted. Methods: We performed a GWAS on 405 patients with diagnosis of SCD using data from the screening phase Walk-PHaSST study (NCT00492531). Patients were 12 years or older, median age of 35 yea
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4

Sowa, Anna, Yue Hu, Mark T. Gladwin, et al. "Genome-Wide Association Study of Chronic Pain in Sickle Cell Disease." Blood 144, Supplement 1 (2024): 5298. https://doi.org/10.1182/blood-2024-208093.

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Background: For many patients with sickle cell disease (SCD), episodes of acute pain occur within the context of debilitating persistent or chronic pain. Over half of adult patients report pain on more than half of the days, and almost a third experience pain on 95% of days. No previous GWAS studies have explored the association of genetic polymorphisms with chronic pain in SCD. Methods: We conducted a genome-wide association study (GWAS) involving 405 SCD patients using data from the screening phase of the Walk-PHaSST study (NCT00492531). Participants were age 12 years and older, with a media
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5

Callaway, Teagan, John J. Strouse, Miriam C. Morey, et al. "Personalized Exercise Intervention for Older Adults with Sickle Cell Disease: The Sicklefit Study." Blood 142, Supplement 1 (2023): 5336. http://dx.doi.org/10.1182/blood-2023-190890.

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Background Older adults with sickle cell disease (SCD) (defined as age ≥ 40 years) experience both SCD and age-related conditions such as recurrent pain episodes, avascular necrosis of the joints, and cardiopulmonary disease that can result in accelerated functional decline. Individuals with SCD experience vaso-occlusive events that lead to reduced oxygen delivery to organs such as bones, muscles, and lungs. Due to these unique risk factors, existing generic exercise programs may be too intense– and even detrimental– for older adults with SCD. Gerofit is a supervised exercise program designed
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6

Mack, A. Kyle, Stephanie A. Pelligra, Richard J. Labotka, Robert E. Molokie, Alexis A. Thompson, and Diana J. Wilkie. "The Utilization of a Computerized Pain Assessment Tool-PAINReportIt® in Adolescents with Sickle Cell Disease." Blood 114, no. 22 (2009): 1535. http://dx.doi.org/10.1182/blood.v114.22.1535.1535.

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Abstract Abstract 1535 Poster Board I-558 Introduction Pain in sickle cell disease (SCD) is a common acute and chronic complication across the life span, but a single multidimensional pain assessment tool is not available that can be used in children, adolescents and adults. The Adolescent Pediatric Pain Tool (APPT) is a self-administered, paper and pencil tool that has been validated in children and adolescents with SCD; the McGill Pain Questionnaire (MPQ) is valid for adolescents and adults. To begin to create a multidimensional pain assessment tool that is valid across the life span, we com
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7

Yin, Lihui, Rupa A. Udani, Mary Parlow, Daniel B. Bellissimo, and Joel A. Brochstein. "Assessment of Erythroid Chimerism in Sickle Cell Patients Undergoing HSCT By Digital Droplet PCR." Blood 124, no. 21 (2014): 563. http://dx.doi.org/10.1182/blood.v124.21.563.563.

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Abstract Sickle cell disease (SCD) is an inherited autosomal recessive blood disorder associated with significant morbidity. Nonmyeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used in severely affected patients with SCD. These transplants result in mixed hematopoietic chimerism so accurate chimerism testing is important for monitoring the status of the transplant. Reconstitution of the erythroid compartment is essential. Since red cells lack a nucleus, DNA-based chimerism assays do not directly assess the chimerism in the erythroid compartment. Several s
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8

Ambruso, Daniel R., Michele LaSalle-Williams, Tuan Le, et al. "Extended Matching of Red Cell Antigens for Patients with Sickle Cell Anemia Decreases the Rate of Alloimmunization." Blood 110, no. 11 (2007): 3389. http://dx.doi.org/10.1182/blood.v110.11.3389.3389.

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Abstract Introduction: Transfusions of packed red blood cells (PRBCs) remain an important treatment for the severe complications of sickle cell anemia. A major complication of transfusions, however, is the formation of alloantibodies to minor red cell antigens. Since 1978 we have provided extended matching for sickle cell patients requiring chronic or intermittent transfusions. We present here a review of our experience with extended matching for decreasing the rate of alloimmunization. Methods: Records of patients with sickle hemoglobinopathies enrolled in the Colorado Sickle Cell Treatment a
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9

Campanaro, Celia M., Jose Carlos Pereira, Jose Hugo Lins Pessoa, Marcia Pradella Halimann, and Monica Favoreto. "Descriptive Study: sleep disorders breathing and Polysomnographic changes in Children and Adolescents with Sickle Cell Disease." Blood 118, no. 21 (2011): 4849. http://dx.doi.org/10.1182/blood.v118.21.4849.4849.

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Abstract Abstract 4849 Introduction: -Sickle Cell Disease (SCD) is a chronic inflammatory disease and a public health problem in Brazil, due its prevalence and Brazilian people high miscegenation. The hypoxia is one of the trigger for vessel occlusive crises in SCD and the quality of sleep is important to maintain a good tissue oxygenation. The search for sleep-disordered breathing (SDB) must be made based on history, physical examination and polysomnography (PSN). These include the diagnosis of airway obstruction and sleep apnea/hypopnea, obstructive syndrome (SAHOS). The objective confirmati
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10

Hoppe, Carolyn C., Joseph A. Jakubowski, Wendra M. Foster, Lori E. Heath, Sreekumar Pillai, and Bhatnagar Pallav. "Candidate Gene Associations with Vaso-Occlusive Crisis in Children with Sickle Cell Anemia Enrolled in the Multinational DOVE Trial." Blood 130, Suppl_1 (2017): 962. http://dx.doi.org/10.1182/blood.v130.suppl_1.962.962.

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Abstract Introduction: Sickle cell disease (SCD) is complex, with marked inter-individual variability in disease severity. The clinical heterogeneity of SCD is largely influenced by genetic factors, including several well-established modifiers of fetal hemoglobin (HbF) levels within the beta globin locus, BCL11A, and HBS1L-MYB genes. However, little is known about genetic factors that may influence variability in treatment response, particularly in clinical trials assessing potential therapeutic agents for SCD. The DOVE (Determining Effects of Platelet Inhibition on Vaso-Occlusive Events) stud
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