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Relevant bibliographies by topics / SSA antibodies

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Academic literature on the topic 'SSA antibodies'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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Journal articles on the topic "SSA antibodies"

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Bossuyt, Xavier, Johan Frans, Ann Hendrickx, Godelieve Godefridis, René Westhovens, and Godelieve Mariën. "Detection of Anti-SSA Antibodies by Indirect Immunofluorescence." Clinical Chemistry 50, no. 12 (2004): 2361–69. http://dx.doi.org/10.1373/clinchem.2004.035964.

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Abstract Background: HEp-2 cells that overexpress the human 60-kDa SSA antigen have been used to improve sensitivity and specificity for the detection of anti-SSA antibodies by indirect immunofluorescence. We describe a survey on the detection of anti-SSA antibodies using a commercial substrate that overexpresses SSA. Methods: The evaluation was done on 18 371 consecutive samples submitted to the laboratory for detection of anti-nuclear antibodies, from which 188 anti-SSA antibody-containing and clinically documented samples were obtained. The presence of anti-SSA antibodies produced a distinc

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Wermuth, Douglas J. "Anti-Ro/SSA Antibodies." Archives of Dermatology 121, no. 3 (1985): 335. http://dx.doi.org/10.1001/archderm.1985.01660030057018.

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Urbanski, Geoffrey, Aline Gury, Pascale Jeannin, et al. "Discordant Predictions of Extraglandular Involvement in Primary Sjögren’s Syndrome According to the Anti-SSA/Ro60 Antibodies Detection Assay in a Cohort Study." Journal of Clinical Medicine 11, no. 1 (2022): 242. http://dx.doi.org/10.3390/jcm11010242.

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Electrophoresis-derived techniques for anti-SSA/Ro60 KDa (anti-SSA) antibodies detection have been progressively replaced by methods using non-native antigens. We aimed to compare the patients’ phenotypes and the occurrence of extraglandular manifestations in primary Sjögren’s syndrome according to the method used to detect anti-SSA antibodies. Sera from patients with a diagnosis of pSS according to ACR/EULAR 2016 criteria between 2008 and 2017 were tested for anti-SSA antibodies using methods with non-native antigens (magnetic bead multiplex assay; line immunoassays) and one with native antig

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Smeele, H. T., L. F. Perez-Garcia, J. M. J. Cornette, M. W. Schreurs, and R. Dolhain. "POS0541 LOW PREVALENCE OF SSA (anti-Ro) AND SSB (anti-La) AUTOANTIBODIES IN FEMALE RHEUMATOID ARTHRITIS PATIENTS WITH A WISH TO CONCEIVE." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 504.2–505. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2435.

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Background:The presence of SSA (anti-Ro) and SSB (anti-La) autoantibodies has important clinical implications for female patients with a wish to conceive. The association between maternal levels of these autoantibodies and complete congenital heart block and neonatal Lupus syndrome is well established. Currently guidelines advise to test for these antibodies in all Rheumatoid Arthritis (RA) patients with a wish to conceive (1).Objectives:The objective was to determine the prevalence and titers of SSA and SSB autoantibodies in female patients with rheumatoid arthritis and a wish to conceive or

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Yoshida, Akira, Shunya Nagata, Yuka Okazaki, Hironari Hanaoka, Takahisa Gono, and Masataka Kuwana. "Dissociating Autoantibody Responses against Ro52 Antigen in Patients with Anti-Synthetase or Anti-MDA5 Antibodies." Diagnostics 13, no. 24 (2023): 3621. http://dx.doi.org/10.3390/diagnostics13243621.

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We aimed to dissociate the autoantibody response against the Ro52 protein in patients with anti-synthetase or anti-melanoma differentiation-associated gene 5 (MDA5) antibodies to explore the potential roles of different anti-Ro52 autoantibody responses in disease subclassification. This study used a single-center, prospective myositis cohort involving 122 consecutive patients with anti-synthetase antibodies identified by RNA immunoprecipitation (RNA-IP) and 34 patients with anti-MDA5 antibodies detected using enzyme immunoassay (EIA). Anti-Ro52 antibodies were measured using commercial EIA kit

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Gaither, K. K., and J. B. Harley. "A shared idiotype among human anti-Ro/SSA autoantibodies." Journal of Experimental Medicine 169, no. 5 (1989): 1583–88. http://dx.doi.org/10.1084/jem.169.5.1583.

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Idiotypes and antiidiotypes are thought to be important immune regulators and have provided clues for the origin and pathogenicity of autoantibodies. Many lupus and Sjögren's syndrome patients, as well as most neonatal lupus infants with congenital heart block or dermatitis, have antibodies to the ribonucleoprotein Ro/SSA, which is one of a group of RNA-protein autoantigens commonly found in human lupus sera. To characterize the fine specificity of anti-Ro/SSA antibodies, a rabbit antidiotypic serum was prepared against polyclonal affinity purified anti-Ro/SSA F(ab')2. The resulting antiidioty

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Yoshimi, Ryusuke, Atsuhisa Ueda, Keiko Ozato, and Yoshiaki Ishigatsubo. "Clinical and Pathological Roles of Ro/SSA Autoantibody System." Clinical and Developmental Immunology 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/606195.

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Anti-Ro/SSA antibodies are among the most frequently detected autoantibodies against extractable nuclear antigens and have been associated with systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). Although the presence of these autoantibodies is one of the criteria for the diagnosis and classification of SS, they are also sometimes seen in other systemic autoimmune diseases. In the last few decades, the knowledge of the prevalence of anti-Ro/SSA antibodies in various autoimmune diseases and symptoms has been expanded, and the clinical importance of these antibodies is increasing. No

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Bason, C., I. Pagnini, A. Brucato, et al. "Congenital heart block and immune mediated sensorineural hearing loss: possible cross reactivity of immune response." Lupus 26, no. 8 (2016): 835–40. http://dx.doi.org/10.1177/0961203316682099.

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Immune-mediated sensorineural hearing loss may complicate systemic autoimmune diseases. We have previously reported the presence of antibodies directed against inner ear antigens in patients with Cogan syndrome, a disease characterized by sudden hearing loss and interstitial keratitis. Such autoantibodies cross-react with an epitope of SSA/Ro60 protein. Anti-Ro/SSA antibodies in pregnant women cross the placenta and reach the fetal tissues inducing an immune-mediated damage of the cardiac conduction system. We wanted to evaluate whether mothers with anti-Ro/SSA antibodies who gave birth to chi

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Carretero Bellon, Juan M., Laia Brunet-Garcia, Joan Sanchez de Toledo, and Stefano Congiu. "Neonatal Rupture of the Tricuspid Valve and Maternal Lupus: Is There a Correlation?" World Journal for Pediatric and Congenital Heart Surgery 13, no. 2 (2021): 260–63. http://dx.doi.org/10.1177/21501351211044128.

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Valve dysfunction is not widely recognized as a feature in newborns born to mothers with positive anti-Ro/SSA antibodies, and only scarce reports have suggested an association between rupture of the atrioventricular valve tensor apparatus and these maternal antibodies. We report the follow-up from fetal life to the time of postnatal surgery of a patient with severe tricuspid regurgitation due to a flail of the anterior tricuspid valve leaflet who was born to an anti-Ro/SSA antibodies positive mother.

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Franceschini, F., and I. Cavazzana. "Anti-Ro/SSA and La/SSB antibodies." Autoimmunity 38, no. 1 (2005): 55–63. http://dx.doi.org/10.1080/08916930400022954.

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Dissertations / Theses on the topic "SSA antibodies"

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Pourmand, Nader. "RNA-protein complexes as autoantigens : cell and molecular biology of Ro/SSA and disease associations of anti-Ro/SSA antibodies /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3655-2/.

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Evers, Patrick D. M. D. "Prenatal Heart Block Screening in Mothers With SSA/SSB Auto-antibodies: Targeted Screening Protocol is a Cost-Effective Strategy." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1552379621451565.

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Hoxha, Ariela. "New insight into the pathogenesis and treatment of autoimmune congenital heart block." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3422991.

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Background. Congenital atrioventricular block (CHB) is the most frequent manifestation of neonatal lupus which is attributed to anti-Ro/SSA and/or anti-La/SSB-mediated inflammation and subsequent fibrosis of the atrioventricular node. Despite the observation of a direct role for maternal antibodies in inducing CHB both in vitro and in vivo studies, the mechanisms involved remain unclear. Currently no therapy is found to be effective in the treatment of 2nd and 3rd degree CHB induced by maternal antibodies; also because the rarity of the disease does not allow for controlled clinical trials.

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Scaramuzzi, Karina. "Investigação dos mecanismos de ação da sílica mesoporosa nanoestruturada SBA-15 como adjuvante." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-07062014-111900/.

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Sílicas mesoporosas, como a SBA-15, constituem-se de partículas de óxido de silício que, devido às suas propriedades físico-químicas apresentam potencial adjuvante. Para entender os mecanismos de ação da SBA-15, camundongos foram imunizados, pelas vias oral e/ou subcutânea (s.c.), com a proteína recombinante HBsAg ou ovalbumina (OVA) e apresentaram aumento significativo nos títulos de anticorpos específicos após imunização s.c. com ambos os antígenos em sílica; entretanto, somente a administração de HBsAg: SBA-15 induziu a produção de anticorpos pela via oral. O efeito da sílica na ativação de

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Scaramuzzi, Karina. "Efeito adjuvante da sílica mesoporosa nanoestruturada SBA-15 na imunização pela via oral." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-07102009-091507/.

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A sílica nanoestruturada SBA-15 é um polímero que devido à suas propriedades físico-químicas apresenta grande potencial como adjuvante de mucosas. A imunização pela via oral de camundongos com a vacina contra Hepatite A ou gama globulina humana adsorvida a SBA-15 revelou aumento nos títulos de anticorpos específicos IgG e IgA, comprovando que a sílica não interfere na polarização da resposta imunológica dos tipos TH1 ou TH2. Ensaios por citometria de fluxo indicaram que a SBA-15 atuou no recrutamento de fagócitos e no aumento dos números de linfócitos B e T nas placas de Peyer e linfonodos mes

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NDONI, ENEA. "Characterization of the immune response and cross protection activity elicited by the Neisserial Heparin Binding Antigen (NHBA), a component of the 4CMenB vaccine." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1011542.

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Invasive disease caused by capsular group B Neisseria meningitidis (MenB) is life threating disease causing hundred thousands of deaths every year, still remaining an unmet medical need in many countries. Although disease can be observed at all age groups, infants and adolescents are the most at risk populations showing the highest incidence in case numbers. Since the MenB capsule was not-immunogenic the development of a MenB vaccine which makes the use of other antigens becomes necessary. 4CMenB is a multicomponent vaccine against serogroup B N. meningitidis composed by three major protein an

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Lin, Po-i., and 林博毅. "Production of polyclonal antibodies against sea bass leucocytes and cytokines induced by E.coli DNA." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/79758179472361948226.

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碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>98<br>Bacterial genimic DNA contains unmethylated CpG motifs can activate the vertebrate immune system, and it has been reported CpG oligodeoxyribonucleotides may activate the osteichthyes immune system effectively. Previous study in our laboratory showed E.coli DNA was able to induce sea bass(Lates calcarifer) head kidney cells to proliferate and produce proliferation inducing factors (PIFs). In this study, polyclonal antibodies were produced to neutralize the PIFs produced by E.coli DNA treated sea bass head kidney cells. When PIFs were depleted, the proliferat

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Books on the topic "SSA antibodies"

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Denton, Christopher P., and Pia Moinzadeh. Systemic sclerosis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0121.

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The term 'scleroderma' describes a group of conditions in which the development of thickened, fibrotic skin is a cardinal feature. This includes localized forms of scleroderma (e.g. morphoea) and also systemic forms of the disease that are more correctly termed systemic sclerosis. Systemic sclerosis (SSc) is a multiorgan, autoimmune disease that has a high clinical burden and mortality, due to affecting the skin as well as internal organs. As with other related diseases there is a female predominance and marked clinical diversity. The pathogenesis of SSc is not fully elucidated; it includes en

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Book chapters on the topic "SSA antibodies"

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Franceschini, Franco, P. Calzavara-Pinton, L. Valsecchi, et al. "Chilblain Lupus Erythematosus is Associated with Antibodies to SSA/Ro." In Rheumaderm. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4857-7_24.

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Trier, Nicole Hartwig. "Detection of SSA and SSB Antibodies Associated with Primary Sjögren’s Syndrome Using Enzyme-Linked Immunosorbent Assay." In Autoantibodies. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8949-2_19.

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Wright, S. F. "Serology and Conjugation of Antibodies." In SSSA Book Series. Soil Science Society of America, 2018. http://dx.doi.org/10.2136/sssabookser5.2.c28.

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Ju, S. T., T. Shirahama, K. Miura, and A. S. Cohen. "Generation and Use of Site-Specific Antibodies Against SAA." In Amyloid and Amyloidosis 1990. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3284-8_20.

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Hazenberg, Bouke P. C., Pieter C. Limburg, Johan Bijzet, and Martin H. van Rijswijk. "SAA Versus CRP Serum Levels in Different Inflammatory Conditions, Studied by Elisa Using Polyclonal Anti-AA and Monoclonal Anti-SAA Antibodies." In Amyloid and Amyloidosis. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4757-0298-9_38.

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Vitela, Roger A. Levy Veronica S., and MD Mirhelen M. Abreu. "Useful Studies:Blood Tests, Imaging, Biopsies, and Beyond." In The New SJogren’s Syndrome Handbook. Oxford University PressNew York, NY, 2005. http://dx.doi.org/10.1093/oso/9780195172287.003.0012.

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Abstract The Revised European Diagnostic criteria of primary Sjogren’s syndrome includes anti-Ro/SSA and/or anti-La/SSB antibodies as one of the six items. The antinuclear antibody (ANA) test is a commonly performed serologic assay for aiding in the diagnosis of a few systemic autoimmune diseases, such as systemic lupus erythematosus (SLE), scleroderma, mixed connective tissue disease, and Sjogren’s. The test is based on an immune fluorescent technique and is in most instances dependent on a subjective analysis. When ANA is positive, it does not mean that an autoimmune disease is present; it c

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Riemekasten, Gabriela, Jens Y. Humrich, and Falk Hiepe. "Antibodies Against ENA (Sm, RNP, SSA, SSB)." In Dubois' Lupus Erythematosus and Related Syndromes. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-323-47927-1.00028-1.

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Radin, Massimo, Karen Schreiber, and Savino Sciascia. "Antibodies as risk factors for adverse maternal and foetal outcomes." In Practical management of the pregnant patient with rheumatic disease, edited by Karen Schreiber, Eliza Chakravarty, and Monika Østensen. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198845096.003.0006.

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A variety of autoantibodies associated with Rheumatic diseases have been associated with adverse maternal and foetal pregnancy outcomes. For instance, pregnancy morbidity in women with antiphospholipid antibodies (aPL) include unexplained consecutive recurrent 1st trimester pregnancy loss (<10 weeks’ gestation), any 2nd or 3rd trimester pregnancy loss, premature birth <34 weeks due to conditions associated with placental insufficiency including severe pre-eclampsia, eclampsia, placental abruption, foetal growth restriction, and intrauterine death. Moreover, antibodies against extractable

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Miller, Aaron E., Tracy M. DeAngelis, Michelle Fabian, and Ilana Katz Sand. "Ataxia and Orthostasis." In Neuroimmunology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190693190.003.0008.

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Neurological complications occur in approximately 20% of patients with Sjögren’s syndrome. Most commonly, patients have peripheral manifestations, including sensory ataxic ganglionopathy, painful sensory neuropathy, cranial neuropathies, and radiculoneuropathies. Central nervous system manifestations, including multiple sclerosis–like conditions, may also occur. Sensory ataxic ganglionopathy in Sjögren’s typically begins with distal paresthesias, which then may spread proximally. This is followed by gait ataxia and, in severe cases, significant proprioceptive abnormalities in the hands as well

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"Anti-Ro/SSA and Anti-La/SSB Antibodies." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_308.

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Conference papers on the topic "SSA antibodies"

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Mavragani, C., and HM Moutsopoulos. "SP0069 Pregnancy outcome and anti-ro/ssa antibodies." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.23.

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Vagts, C., C. Ascoli, and N. Sweiss. "Clinical Significance of Anti-SSA Antibodies in Patients with Sarcoidosis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4491.

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Kammerer, Susanne. "Severe lung involvement in SSc linked to anti-Ro/SSA antibodies." In EULAR 2024 Congress, edited by Dennis McGonagle. Medicom Medical Publishers, 2024. http://dx.doi.org/10.55788/bbffe179.

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WILLERS, THIAGO, LILIAN SCUSSEL LONZETTI, TATIANA FREITAS TOURINHO, et al. "CORRELATION BETWEEN DIGITAL ULCERS AND SSA ANTIBODIES IN SYSTEMIC SCLEROSIS PATIENTS: A PRELIMINARY STUDY." In 36º Congresso Brasileiro de Reumatologia. Editora Blucher, 2019. http://dx.doi.org/10.5151/sbr2019-382.

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Plaçais, L., F. Carrat, L. Carbillon, et al. "AB0551 Obstetrical morbidity related to anti-ssa antibodies: data from a french monocentric retrospective study." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5580.

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Zecca, Erika, Mattia Bellan, Domizia Vecchio, et al. "FRI0258 ANTI-RO/SSA POSITIVITY, ANTI-AQUAPORIN4 ANTIBODIES AND CENTRAL NERVOUS SYSTEM INVOLVEMENT: A RETROSPECTIVE STUDY ON A CONTROVERSIAL CORRELATION." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5588.

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Bertocchi, S., E. Pedretti, R. Rovelli, et al. "PO.3.56 Anti- Ro/SSA antibodies and electrocardiographic abnormalities in SLE patients: preliminary data of a multidisciplinary study in a monocentric cohort." In 13th European Lupus Meeting, Stockholm (October 5–8, 2022). Lupus Foundation of America, 2022. http://dx.doi.org/10.1136/lupus-2022-elm2022.86.

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Santos Faria, M., A. R. Lopes, A. Teodósio Chícharo, et al. "AB1499 BEYOND NEONATAL LUPUS: MATERNAL AND PERINATAL OUTCOMES IN WOMEN WITH ANTI-SSA AND ANTI-SSB ANTIBODIES. EXPERIENCE FROM A MULTIDISCIPLINARY CLINIC." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.5571.

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Burja, B., M. Boubaya, C. Bruni, et al. "OP0013 ANTI-Ro/SSA ANTIBODIES ARE PREDICTIVE OF A MORE SEVERE LUNG INVOLVEMENT IN PATIENTS WITH SYSTEMIC SCLEROSIS: A STUDY FROM THE EUSTAR HDATABASE." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.1670.

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Martel, M. E., A. Leurs, D. Launay, et al. "OP0289 PREVALENCE OF ANTI-RO52-KDA/SSA (TRIM21) ANTIBODIES AND ASSOCIATED CLINICAL PHENOTYPE IN SYSTEMIC SCLEROSIS: DATA FROM A FRENCH COHORT, A SYSTEMATIC REVIEW AND META-ANALYSIS." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.3913.

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Reports on the topic "SSA antibodies"

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Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580665.bard.

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Many factors affect growth rate in fish: environmental, nutritional, genetics and endogenous (physiological) factors. Endogenous control of growth is very complex and many hormone systems are involved. Nevertheless, it is well accepted that growth hormone (GH) plays a major role in stimulating somatic growth. Although it is now clear that most, if not all, components of the GH-IGF axis exist in fish, we are still far from understanding how fish grow. In our project we used as the experimental system a marine fish, the gilthead sea bream (Sparus aurata), which inhabits lagoons along the Mediter

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