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1
Matthews, Elizabeth. "Invasive Security Practices in Secondary Public Schools and the Role of School-Based Parent Involvement." Education and Society 37, no. 2 (2019): 25–43. http://dx.doi.org/10.7459/es/37.2.03.
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Typically, school administrators determine their school’s security practices, but parental involvement may also play an important role in school security decisions. Data from the 2015‐2016 School Survey on Crime and Safety (SSOCS 2016) was used to examine the relationship between parental involvement and the presence of physically invasive security practices in secondary schools. Invasive security was defined as the emplacement of metal detectors, contraband sweeps or drug sniffing canines. Analyses revealed that high levels of school-based parent engagement were associated with lower odds of employing invasive security measures in the school setting.
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Mouchtouri, Varvara, Diederik Van Reusel, Nikolaos Bitsolas, et al. "European Web-Based Platform for Recording International Health Regulations Ship Sanitation Certificates: Results and Perspectives." International Journal of Environmental Research and Public Health 15, no. 9 (2018): 1833. http://dx.doi.org/10.3390/ijerph15091833.
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The purpose of this study was to report the data analysis results from the International Health Regulations (2005) Ship Sanitation Certificates (SSCs), recorded in the European Information System (EIS). International sea trade and population movements by ships can contribute to the global spread of diseases. SSCs are issued to ensure the implementation of control measures if a public health risk exists on board. EIS designed according to the World Health Organization (WHO) “Handbook for Inspection of Ships and Issuance of SSC”. Inspection data were recorded and SSCs issued by inspectors working at European ports were analysed. From July 2011–February 2017, 107 inspectors working at 54 ports in 11 countries inspected 5579 ships. Of these, there were 29 types under 85 flags (including 19 EU Member States flags). As per IHR (2005) 10,281 Ship Sanitation Control Exception Certificates (SSCECs) and 296 Ship Sanitation Control Certificates (SSCCs) were issued, 74 extensions to existing SSCs were given, 7565 inspection findings were recorded, and 47 inspections were recorded without issuing an SSC. The most frequent inspection findings were the lack of potable water quality monitoring reports (23%). Ships aged ≥12 years (odds ratio, OR = 1.77, 95% confidence intervals, CI = 1.37–2.29) with an absence of cargo at time of inspection (OR = 3.36, 95% CI = 2.51–4.50) had a higher probability of receiving an SSCC, while ships under the EU MS flag had a lower probability of having inspection findings (OR = 0.72, 95% CI = 0.66–0.79). Risk factors to prioritise the inspections according to IHR were identified by using the EIS. A global information system, or connection of national or regional information systems and data exchange, could help to better implement SSCs using common standards and procedures.
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Styrin, Evgeny, and Natalya Dmitrieva. "Evaluating Public Organizations Using Open Data." International Journal of Electronic Government Research 13, no. 4 (2017): 1–14. http://dx.doi.org/10.4018/ijegr.2017100101.
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Information openness and stakeholder involvement through ICT become the driving factors of public organization change. In this article, an ecosystem approach is embraced to study the social sphere organizations (SSOs), such as hospitals, schools, and libraries. SSOs report on their activities by publishing information on the Web which can be used to evaluate the effectiveness and efficiency of these organizations by the public. The opening of data transforms the relationship between SSOs and other stakeholders. In this article, the institutionalization of SSO evaluation system in Russia is studied. The critical role of open data is demonstrated and the inclusion of stakeholders was found to be a key factor to make the evaluation system truly effective. Their study reveals that an ecosystem approach ensures that stakeholder demands are included in SSO evaluation and assessment process. Finally, by summarizing Russian experiences, the authors conclude with problem-oriented recommendations for open government tool application to institutionalize government practices targeted at open government principle implementation.
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Spoto, F., P. Tanga, F. Mignard, et al. "Gaia Data Release 2." Astronomy & Astrophysics 616 (August 2018): A13. http://dx.doi.org/10.1051/0004-6361/201832900.
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Context. The Gaia spacecraft of the European Space Agency (ESA) has been securing observations of solar system objects (SSOs) since the beginning of its operations. Data Release 2 (DR2) contains the observations of a selected sample of 14,099 SSOs. These asteroids have been already identified and have been numbered by the Minor Planet Center repository. Positions are provided for each Gaia observation at CCD level. As additional information, complementary to astrometry, the apparent brightness of SSOs in the unfiltered G band is also provided for selected observations. Aims. We explain the processing of SSO data, and describe the criteria we used to select the sample published in Gaia DR2. We then explore the data set to assess its quality. Methods. To exploit the main data product for the solar system in Gaia DR2, which is the epoch astrometry of asteroids, it is necessary to take into account the unusual properties of the uncertainty, as the position information is nearly one-dimensional. When this aspect is handled appropriately, an orbit fit can be obtained with post-fit residuals that are overall consistent with the a-priori error model that was used to define individual values of the astrometric uncertainty. The role of both random and systematic errors is described. The distribution of residuals allowed us to identify possible contaminants in the data set (such as stars). Photometry in the G band was compared to computed values from reference asteroid shapes and to the flux registered at the corresponding epochs by the red and blue photometers (RP and BP). Results. The overall astrometric performance is close to the expectations, with an optimal range of brightness G ~ 12 − 17. In this range, the typical transit-level accuracy is well below 1 mas. For fainter asteroids, the growing photon noise deteriorates the performance. Asteroids brighter than G ~ 12 are affected by a lower performance of the processing of their signals. The dramatic improvement brought by Gaia DR2 astrometry of SSOs is demonstrated by comparisons to the archive data and by preliminary tests on the detection of subtle non-gravitational effects.
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Hiller, S. A., B. Kabius, W. Probst, et al. "Performance Data of a New 2048 X 2048 Pixel Slow-Scan CCD Camera For TEM." Microscopy and Microanalysis 6, S2 (2000): 732–33. http://dx.doi.org/10.1017/s1431927600036151.
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Excellent linearity and high sensitivity have made SSCs the ideal image detector for almost every TEM application. Their ability to make high quality digital images available within fraction of seconds for further evaluation and processing in a PC, have made them a non-dispensable accessory for any modern TEM. However, despite their excellent characteristics, SSCs provide a restricted number of individual image points in respect to a negative, what is considered to be the main disadvantage of this detector. To compensate for this, CCDs with 2048x2048 pixel are available since some time. SSCs using these 2kx2k CCD arrays not only provide 4 times the pixel number but also offer a lot more options people have waiting for: e. g. highly resolved low-dose or ESI images with significantly improved signal to noise ratio, or higher resolved images for diffraction analysis and holographic reconstruction.
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Widyati, Fasaila Nadif, and Hani Irawati. "Studi Literatur: Peningkatan Oral Activity dan Hasil Belajar Kognitif melalui Penerapan Model Pembelajaran Search, Solve, Create and Share (SSCS) Materi Sistem Ekskresi pada Manusia." INKUIRI: Jurnal Pendidikan IPA 9, no. 2 (2021): 126. http://dx.doi.org/10.20961/inkuiri.v9i2.50084.
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Dominansi pendekatan pembelajaran teacher center menyebabkan <em>oral activity</em> siswa dan hasil belajar kognitif siswa rendah pada materi sistem ekskresi. Penerapan model pembelajaran SSCS diharapkan dapat meningkatkan <em>oral activity</em> dan hasil belajar kognitif siswa. Penelitian ini bertujuan untuk mengetahui peningkatan <em>oral activity</em> dan hasil belajar kognitif siswa melalui model pembelajaran SSCS pada materi sistem ekskresi berdasarkan studi literatur. Jenis penelitian ini merupakan penelitian studi literatur. Artikel ilmiah sebagai data penelitian berasal dari jurnal nasional, prosiding dan repository. Validasi artikel dilakukan dengan pertimbangan artikel ilmiah bersifat open access, kualitas metodologi penelitian, kualitas penyajian data dan pembahasan, kecukupan data yang relevan, referensi mutakhir. Teknik pengumpulan data dengan cara koding definisi dan format penyajian data dalam tabel. Teknik analisis data menggunakan analisis deskriptif. Berdasarkan studi literatur menunjukkan bahwa model pembelajaran SSCS dapat meningkatkan <em>oral activity</em> dan hasil belajar kognitif siswa. Hal ini diketahui melalui analisis data artikel ilmiah relevan terdapat pengaruh yang signifikan terhadap peningkatan <em>oral activity</em> dan hasil belajar kognitif. <em>Oral activity</em> siswa terlihat dalam penerapan model pembelajaran SSCS pada tahapan solve dan share. Model pembelajaran SSCS mendukung siswa mengembangkan kemampuan berpikir sehingga perolehan hasil belajar kognitif siswa meningkat. Selain itu, model pembelajaran SSCS dapat diterapkan pada materi sistem ekskresi.
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Gwyn, Stephen D. J., Norman Hill, and JJ Kavelaars. "Solar System Object Image Search: A precovery search engine." Proceedings of the International Astronomical Union 10, S318 (2015): 270–73. http://dx.doi.org/10.1017/s1743921315008704.
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AbstractWhile regular astronomical image archive searches can find images at a fixed location, they cannot find images of moving targets such as asteroids or comets. The Solar System Object Image Search (SSOIS) at the Canadian Astronomy Data Centre allows users to search for images of moving objects, allowing precoveries. SSOIS accepts as input either an object designation, a list of observations, a set of orbital elements, or a user-generated ephemeris for an object. It then searches for observations of that object over a range of dates. The user is then presented with a list of images containing that object from a variety of archives. Initially created to search the CFHT MegaCam archive, SSOIS has been extended to other telescopes including Gemini, Subaru/SuprimeCam, WISE, HST, the SDSS, AAT, the ING telescopes, the ESO telescopes, and the NOAO telescopes (KPNO/CTIO/WIYN), for a total of 24.5 million images. As the Pan-STARRS and Hyper Suprime-Cam archives become available, they will be incorporated as well. The SSOIS tool is located on the web at http://www.cadc-ccda.hia-iha.nrc-cnrc.gc.ca/en/ssois/.
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Wang, Min, Wene Zhao, Fuqiang Wang, et al. "Bioinformatics Analysis of Transcriptomic Data Reveals Refined Functional Networks for the Self-Renewal of Mouse Spermatogonial Stem Cells." Stem Cells International 2018 (July 8, 2018): 1–9. http://dx.doi.org/10.1155/2018/5842714.
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Spermatogonial stem cells (SSCs) are exquisitely regulated to reach a balance between proliferation and differentiation in the niche of seminiferous epithelium. Several extrinsic factors such as GDNF are reported to switch the transition, activating various intrinsic signaling pathways. Transcriptomics analysis could provide a comprehensive landscape of gene expression and regulation. Here, we reanalyzed a previously published transcriptome of two cell types (standing for self-renewing and differentiating SSCs correspondingly). First, we proposed a new parameter, the expression index, to sort the genes considering both absolute and relative expression levels. Using a dynamic statistical model, we identified a list of 1119 candidate genes for SSC self-renewal with the best enrichment of canonical markers. Finally, based on interaction relations, we further optimized the list and constructed a refined network containing integrated information of interactions, expression alternations, biological functions, and disease associations. Further annotation of the 521 refined genes involved in the network revealed an enrichment of well-studied signaling pathways. We believe that the refined network could help us better understand the regulation of SSCs’ fates, as well as find novel regulators or targets for SSC self-renewal or preservation of male fertility.
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Djumadi, Djumadi, and Erfan Budi Santoso. "Pengaruh Model Pembelajaran Search, Solve, Create, and Share dan Predict Observe Explain terhadap Hasil Belajar Biologi Siswa Kelas VIII SMPN 1 Gondangrejo Karanganyar Tahun Ajaran 2013/2014." Jurnal VARIDIKA 26, no. 1 (2015): 11–20. http://dx.doi.org/10.23917/varidika.v26i1.728.
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This study has objectives (1) to know the effect of SSCS learning model and POE toward the achievement of students learning biology, (2) the difference between the achievement of students learning biology using SSCS learning model and POE. This is quasi experimental research with randomized subjects posttest only control group design. The population are three classes randomly selected from SMP Negeri 1 Gondangrejo Karanganyar 2013/2014. The first class, VIIID, is thaught by POE learning model. The second class is SSCS learning model, and the third, as control class, is thaught by variative lecturing. Data are collected by test, quessionaire, observation, and documentation.Then data are analysed by validity, reliability, difficulty test index. The results are (1) there is an effect of SSCS learning model and POE toward the achievement of students learning biology at three aspects: cognitive, affective and psychomotoric. It can be seen on the average of students learning achievement at experiment class and control class with the significance value < 0,05. The proceed result of anova Post Hoc test Scheffe indicates that there is a difference the achievement of students learning biology using SSCS learning model and POE at affective and psichomototic domain, but it does not happen in cognitive domain. The conclusion is (1) there is an effect of the achievement of students learning biology using SSCS learning model and POE, (2) SSCS learning model is more effective than POE.
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Karaszewski, Robert, Paweł Modrzyński, and Joanna Modrzyńska. "The Use of Blockchain Technology in Public Sector Entities Management: An Example of Security and Energy Efficiency in Cloud Computing Data Processing." Energies 14, no. 7 (2021): 1873. http://dx.doi.org/10.3390/en14071873.
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Blockchain technology is currently one of the trends considered to have a tremendous future ahead. It ensures data security, data sharing protection and automation development—elements that are of colossal importance in the era of cloud solutions, big data and Internet of Things (IoT) reality. Additionally, blockchain technology allows one to create new programmable ecosystems on an unprecedented scale. The implementation of blockchain technology leads not only to improving the flow of documents and data storage, as is the case with the creation of shared service centers (SSCs), but—as this paper shows—allows one to reduce the carbon footprint when servicing SSCs at a considerably higher organizational level at the same time. The example of an SSC in Elbląg, Poland, proves that cloud solutions enabling electronic documents flow and data storage combined with blockchain technology are tools essential for further SSCs development. Furthermore, such tools allow us not only to obtain economic effects (i.e., cost reduction), but also to achieve positive ecological effects (i.e., carbon footprint reduction).
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Perdelwitz, V., M. Völschow, and H. M. Müller. "A new approach to distant solar system object detection in large survey data sets." Astronomy & Astrophysics 615 (July 2018): A159. http://dx.doi.org/10.1051/0004-6361/201732254.
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Context. The recently postulated existence of a giant ninth planet in our solar system has sparked search efforts for distant solar system objects (SSOs) both via new observations and archival data analysis. Due to the likely faintness of the object in the optical and infrared regime, it has so far eluded detection. Aims. We set out to re-analyze data acquired by the Wide-Field Infrared Survey Explorer (WISE), an all-sky survey well suited for the detection of SSOs. Methods. We present a new approach to SSO detection via parallactic fitting. Using the heliocentric distance as a fit parameter, our code transforms groups of three or more single-observation point sources to heliocentric coordinates under the assumption that all data stem from an object. The fact that the orbit of a distant SSO is approximately linear in heliocentric coordinates over long time-scales can be utilized to produce candidates, which can then be confirmed with follow-up observations. Results. We demonstrate the feasibility of the approach by a posteriori detecting the outer SSO Makemake within WISE data. An all-sky search for Planet Nine yielded no detection. Conclusions. While the postulated Planet Nine eluded detection by our algorithm, we tentatively predict that this new approach to moving-object analysis will enable the discovery of new distant SSOs that cannot be discovered by other algorithms. Especially in cases of sparse data observed over long time spans, our approach is unique and robust due to the use of only one fit parameter.
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Mao, Xinyan, Daosheng Wang, Jicai Zhang, Changwei Bian, and Xianqing Lv. "Dynamically Constrained Interpolation of the Sparsely Observed Suspended Sediment Concentrations in Both Space and Time: A Case Study in the Bohai Sea." Journal of Atmospheric and Oceanic Technology 35, no. 5 (2018): 1151–67. http://dx.doi.org/10.1175/jtech-d-17-0149.1.
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AbstractThe observed suspended sediment concentrations (SSCs) obtained from the water sampling are usually sparsely distributed in both space and time, which are traditionally applied just to calibrate other types of observations. In this study a dynamically constrained interpolation methodology (DCIM) is developed to interpolate these sparsely observed SSCs in the Bohai Sea. In this method the suspended sediment transport model is taken as dynamical constraints to interpolate the observations. Meanwhile, the interpolated results are optimized iteratively by adjusting the key model parameters using the adjoint method.The DCIM is first verified using the synthetic observations produced by twin model runs. The modeling results reveal that this method is effective at interpolating the sparsely observed artificial SSCs, even when the observations are heavily contaminated by data noise. Then, the sparsely observed practical SSCs obtained from a large area survey in the Bohai Sea are interpolated using the DCIM. The interpolated results are verified by randomly selected independent observations. The discrepancies between the interpolated SSCs and the observations are significantly decreased. When all the observations are interpolated, the final interpolated SSCs captured a majority (96.88%) of observations with a factor of 2 and the correlation coefficient between the observed and interpolated SSCs is 0.98. Besides, the interpolated results have presented the reasonable dynamical variations of SSCs in the space and time domains. The modeling results indicate that the DCIM is an effective tool for interpolating the sparsely observed SSCs in both space and time.
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Pichi, Selfia Okta, Erviyenni Erviyenni, and Betty Holiwarni. "Pengembangan Lembar Kegiatan Peserta Didik (LKPD) Berbasis Search, Solve, Create and Share (SSCS) pada Pokok Bahasan Kesetimbangan Ion dan pH Larutan Garam." Jurnal Pijar Mipa 15, no. 5 (2020): 503. http://dx.doi.org/10.29303/jpm.v15i5.1608.
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Penelitian ini bertujuan untuk mengembangkan bahan ajar berupa lembar kegitan peserta didik (LKPD) berbasis search, solve, create and share (SSCS) pada pokok bahasan kesetimbanganion dan pH larutan garam untuk kelas XI tingkat SMA/MA. Jenis penelitian yang digunakan yaitu penelitian pengembangan (Research and Development) dengan model pengembangan 4-D. Objek penelitian yaitu LKPD berbasis SSCS. Instrumen pengumpulan data berupa lembar validasi yang diberikan kepada tiga orang validator dan lembar respon pengguna kepada dua orang guru mata pelajaran kimia dan 20 orang peserta didik kelas XII MIPA SMA dan MA. Teknik analisis data yaitu dengan cara menghitung skor persentase penilaian validasi dan respon pengguna. Hasil penelitian menunjukkan bahwa LKPD berbasis SSCS yang dikembangkan memenuhi kriteria valid dari aspek penilaian substansi isi, kelayakan karakteristik SSCS, kebahasaan, penyajian dan kegrafisan dengan persentase skor keseluruhan sebesar 93,01 %. Respon pengguna berdasarkan lembar tanggapan guru dan tanggapan peserta didik masing-masing memperoleh skor 92,5 % dan 91,43%.
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Ningsih, Eva Fitria. "Implementasi Model Pembelajaran Search, Solve, Create and Share (SSCS) untuk Meningkatkan Kemampuan Berpikir Kreatif Matematis." GAUSS: Jurnal Pendidikan Matematika 2, no. 1 (2019): 25. http://dx.doi.org/10.30656/gauss.v2i1.1441.
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Tujuan utama penelitian ini untuk melakukan studi yang berfokus pada penggunaan model pembelajaran SSCS yang diduga dapat meningkatkan kemampuan berpikir kreatif matematis, ditinjau dari keseluruhan siswa dan kategori Kemampuan Awal Matematika (KAM) siswa (unggul dan asor). Metode penelitian yang digunakan dalam penelitian ini merupakan metode kuasi eksperimen. Penelitian ini menggunakan tes KAM dan tes kemampuan berpikir kreatif matematis. Pengolahan data dalam penelitian ini menggunakan uji-t dan ANOVA dua jalur. Berdasarkan hasil analisis data didapatkan kesimpulan bahwa ditinjau dari keseluruhan, peningkatan kemampuan berpikir kreatif matematis siswa yang memperoleh model pembelajaran SSCS lebih baik daripada kemampuan berpikir kreatif matematis siswa yang memperoleh pembelajaran ekspositori. Apabila ditinjau dari kategori KAM, peningkatan kemampuan berpikir kreatif matematis siswa unggul dan asor yang memperoleh model pembelajaran SSCS lebih baik daripada kemampuan berpikir kreatif matematis siswa unggul dan asor yang memperoleh pembelajaran ekspositori.Kata kunci: Model SSCS, Kemampuan Berpikir Kreatif Matematis
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Kuo, Wen-Chuan, Meng-Chun Kao, Kuang-Yi Chang, et al. "Fiber-needle Swept-source Optical Coherence Tomography System for the Identification of the Epidural Space in Piglets." Anesthesiology 122, no. 3 (2015): 585–94. http://dx.doi.org/10.1097/aln.0000000000000531.
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Abstract Background: Epidural needle insertion is traditionally a blind technique whose success depends on the experience of the operator. The authors describe a novel method using a fiber-needle–based swept-source optical coherence tomography (SSOCT) to identify epidural space. Methods: An optical fiber probe was placed into a hollow 18-gauge Tuohy needle. It was then inserted by an experienced anesthesiologist to continuously construct a series of two-dimensional SSOCT images by mechanically rotating the optical probe. To quantify this observation, both the average SSOCT signal intensities and their diagnostic potentials were assessed. The insertions were performed three times into both the lumbar and thoracic regions of five pigs using a paramedian approach. Results: A side-looking SSOCT is constructed to create a visual image of the underlying structures. The image criteria for the identification of the epidural space from the outside region were generated by the analysis of a training set (n = 100) of ex vivo data. The SSOCT image criteria for in vivo epidural space identification are high sensitivity (0.867 to 0.965) and high specificity (0.838 to 0.935). The mean value of the average signal intensities exhibits statistically significant differences (P &lt; 0.01) and a high discriminatory capacity (area under curve = 0.88) between the epidural space and the outside tissues. Conclusions: This is the first study to introduce a SSOCT fiber probe embedded in a standard epidural needle. The authors anticipate that this technique will reduce the occurrence of failed epidural blocks and other complications such as dural punctures.
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Chang, Shoude, Youxin Mao, and Costel Flueraru. "Dual-Source Swept-Source Optical Coherence Tomography Reconstructed on Integrated Spectrum." International Journal of Optics 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/565823.
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Dual-source swept-source optical coherence tomography (DS-SSOCT) has two individual sources with different central wavelengths, linewidth, and bandwidths. Because of the difference between the two sources, the individually reconstructed tomograms from each source have different aspect ratio, which makes the comparison and integration difficult. We report a method to merge two sets of DS-SSOCT raw data in a common spectrum, on which both data have the same spectrum density and a correct separation. The reconstructed tomographic image can seamlessly integrate the two bands of OCT data together. The final image has higher axial resolution and richer spectroscopic information than any of the individually reconstructed tomography image.
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Satriawan, Rody. "Keefektifan model search, solve, create, and share ditinjau dari prestasi, penalaran matematis, dan motivasi belajar." Jurnal Riset Pendidikan Matematika 4, no. 1 (2017): 87. http://dx.doi.org/10.21831/jrpm.v4i1.7863.
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Tujuan penelitian ini adalah untuk mendeskripsikan keefektifan pembelajaran matematika dengan model search, solve, create, and share (SSCS) dan apakah pembelajaran matematika dengan model SSCS lebih baik dibandingkan dengan model konvensional ditinjau dari prestasi, penalaran matematis, dan motivasi belajar. Penelitian ini merupakan penelitian eksperimen semu dengan desain kontrol grup non-ekuivalen. Populasi dalam penelitian adalah seluruh siswa kelas VIII SMP Muhammadiyah Banguntapan yang terdiri dari lima kelas. Sampel penelitian diambil dua kelas secara acak, yaitu kelas VIII-D dan VIII-E. Analisis data yang digunakan adalah uji T2 Hotteling’s, uji MANCOVA, dan uji lanjut dengan prosedur t-test. Setiap analisis dilakukan pada taraf signifikansi 5%. Hasil penelitian ini adalah pembelajaran matematika dengan model SSCS efektif ditinjau dari prestasi dan motivasi belajar, tetapi tidak efektif ditinjau dari penalaran matematis siswa dan pembelajaran matematika dengan model SSCS lebih baik dibandingkan dengan pembelajaran konvesional ditinjau dari prestasi dan penalaran matematis, tetapi tidak lebih baik ditinjau dari motivasi belajar siswa kelas VIII SMP Muhammadiyah Banguntapan.Kata Kunci: model SSCS, model konvensional, prestasi belajar, penalaran matematis, motivasi belajar siswa The Effectiveness of the Model of Search, Solve, Create, and Share Terms of Achievement, Mathematical Reasoning, and Motivation to Learn AbstractThe purpose of this study is to describe the effectiveness of teaching with the teaching model search, solve, create, and share (SSCS) and to describe whether teaching by teaching model SSCS better than by model conventional regarding students’ achievement, mathematical reasoning, and mathematics learning motivation. This research was quasi-experimental with the non-equivalent control group design. The population was all students of class VIII SMP Muhammadiyah Banguntapan consisting of five classes. The sample taken at random consisted of two classes: classes VIII-D dan VIII-E. Class VIII-D was taught by using the model conventional, while class VIII-E was taught by using the SSCS teaching model. The data were analyzed by using a multivariate test Hotelling's T2, MANCOVA test, and tested further by using t-test procedures. Each analysis regarding at the significance level of 5%. The results showed that: the first, the teaching of mathematics by using the SSCS model is effective regarding students’ achievement and students’ mathematics learning motivation, but it is not effective in terms of mathematical reasoning Banguntapan Muhammadiyah junior high school students of class VIII. The second, the SSCS teaching model is better than the conventional teaching model regarding students’ achievement and mathematical reasoning abilities, but not better terms of students’ mathematics learning the mathematics of class VIII SMP Muhammadiyah Banguntapan.Keywords: teaching model of SSCS, teaching model of conventional, academic achievement, mathematical reasoning ability, mathematics learning motivation
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Pandey, Vivek, Anima Tripathi, and Pawan K. Dubey. "Expression and intracellular localization of Nanos2-homologue protein in primordial germ cells and spermatogonial stem cells." Zygote 27, no. 02 (2019): 82–88. http://dx.doi.org/10.1017/s0967199419000066.
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SummaryThe decision by germ cells to differentiate and undergo either oogenesis or spermatogenesis takes place during embryonic development and Nanos plays an important role in this process. The present study was designed to investigate the expression patterns in rat of Nanos2-homologue protein in primordial germ cells (PGCs) over different embryonic developmental days as well as in spermatogonial stem cells (SSCs). Embryos from three different embryonic days (E8.5, E10.5, E11.5) and SSCs were isolated and used to detect Nanos2-homologue protein using immunocytochemistry, western blotting, reverse transcription polymerase chain reaction (RT-PCR) and flow cytometry. Interestingly, Nanos2 expression was detected in PGCs at day E11.5 onwards and up to colonization of PGCs in the genital ridge of fetal gonads. No Nanos2 expression was found in PGCs during early embryonic days (E8.5 and 10.5). Furthermore, immunohistochemical and immunofluorescence data revealed that Nanos2 expression was restricted within a subpopulation of undifferentiated spermatogonia (As, single type A SSCs and Apr, paired type A SSCs). The same results were confirmed by our western blot and RT-PCR data, as Nanos2 protein and transcripts were detected only in PGCs from day E11.5 and in undifferentiated spermatogonia (As and Apr). Furthermore, Nanos2-positive cells were also immunodetected and sorted using flow cytometry from the THY1-positive SSCs population, and this strengthened the idea that these cells are stem cells. Our findings suggested that stage-specific expression of Nanos2 occurred on different embryonic developmental days, while during the postnatal period Nanos2 expression is restricted to As and Apr SSCs.
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Erin Febri Astuti, Ni Putu, Gede Suweken, and Djoko Waluyo. "PENGARUH MODEL PEMBELAJARAN SEARCH, SOLVE,CREATE AND SHARE (SSCS) TERHADAP PEMAHAMAN KONSEP MATEMATIKA SISWA KELAS VIIII SMP NEGERI 1 BANJAR." Jurnal Pendidikan Matematika Undiksha 9, no. 2 (2019): 84. http://dx.doi.org/10.23887/jjpm.v9i2.19901.
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Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Search, Solve, Create, andShare (SSCS) terhadap pemahaman konsep matematika siswa. Jenis penelitian ini adalah eksperimensemu dengan post-test only control group design. Populasi penelitan ini adalah siswa Kelas VIII SMPNegeri 1 Banjar tahun ajaran 2017/2018 sebanyak 11 kelas. Pengambilan sampel dilakukan denganteknik cluster random sampling. Kemudian dilakukan uji kesetaraan sampel menggunakan uji Anava.Data pemahaman konsep matematika siswa diperoleh melalui tes uraian. Analisis data menggunakan ujitsatu ekor yaitu ekor kanan, dengan taraf signifikansi 5%. Berdasarkan hasil analisis data diperoleh ratarataskor pemahaman konsep matematika kelas eksperimen adalah 33.17 sedangkan pada kelas kontroladalah 27.79. Hasil pengujian dengan uji-t diperoleh nilai thitung = 3,10 dan ttabel = 1,98, sehingga thitung >ttabel, dapat dikatakan bahwa pemahaman konsep matematika siswa yang mengikuti pembelajarandengan model Search, Solve, Create, and Share (SSCS) lebih baik dari pemahaman konsep matematikasiswa yang mengikuti pembelajaran dengan pembelajaran konvensional. Jadi kesimpulannya adalahmodel pembelajaran Search, Solve, Create, and Share (SSCS) berpengaruh positif terhadappemahaman konsep matematika siswa.Kata kunci: model pembelajaran Search, Solve, Create, and Share (SSCS),pembelajaran konvensioal, pemahaman konsep matematika.
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Zhang, Jin, Yingying Liu, Jiaqi Shi, Douglas F. Larson, and Ronald Ross Watson. "Side-Stream Cigarette Smoke Induces Dose–Response in Systemic Inflammatory Cytokine Production and Oxidative Stress." Experimental Biology and Medicine 227, no. 9 (2002): 823–29. http://dx.doi.org/10.1177/153537020222700916.
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Side-stream cigarette smoke (SSCS), a major component of secondhand smoke, induces reactive oxygen species, which promote oxidative damage in tissues and organs. Inflammatory cytokines play an important role in the pathogenesis of atherosclerosis and heart failure. The present 4-month study examined the effect of various chronic SSCS exposure levels on splenic inflammatory cytokine secretion, heart contractile function, and pathology at 60- and 120-min per day, 5 days per week, for a total of 16 weeks. Tissue vitamin E level and lipid peroxide production also were tested to estimate the oxidative stress. The study found that the pro-inflammatory cytokines, interleukin (IL)-6, tumor necrosis factor (TNF)-α, and IL-1β, significantly increased in 120-min SSCS-exposed mice. Decreased stroke volume and increased peripheral arterial resistance were observed in mice exposed to 120-min SSCS per day. Heart pathology was only found in 120-min SSCS-exposed mice. Cardiac and hepatic antioxidant vitamin E levels were decreased as a result of oxidative stress. Hepatic lipid peroxides were Increased upon 60-min SSCS exposure. The data also demonstrated that the cardiac α-tocopherol level has a strong correlation with stroke volume; splenic IL-1β has a strong negative correlation with stroke volume; splenic TNF-α has a very strong negative correlation with stroke volume. In conclusion, SSCS exposure induced systemic inflammatory responses. SSCS exposure also accentuated systemic lipid peroxidation with depletion of cardiac and hepatic antioxidant vitamin E level. Finally, SSCS exposure at 120 min per day decreased stroke volume and increased vascular resistance. Systemic IL-1 β and TNF-α production are responsible for heart contractile dysfunction. Free radicals may be responsible for the progression to heart contractile dysfunction induced, in part, by SSCS. Oxidized lipoprotein could contribute to the vascular functional changes. Exploring the mechanism of vascular dysfunction in mice is warranted. A more precise quantification of the smoking exposure dose in mice needs to be determined as well.
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Eliza, Rivdya, and Fitri Aulia. "Pembelajaran Matematika dengan Model Search, Solve, Create and Share (SSCS) di MAN 1 Muara Labuh." Math Educa Journal 1, no. 2 (2017): 200–210. http://dx.doi.org/10.15548/mej.v1i2.27.
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The purpose of this research are: 1) to know the learning activity of learners mathematics which is taught by Search, Solve, Create, and Share (SSCS), and 2) model to know the ability of problem solving of mathematics learners who taught by SSCS learning model in the class XI MIA MAN 1 Muara Labuh academic year 2016/2017. This research belongs to a kind of quasi-experimental research with randomized control group only design. In this study design, a group of subjects taken from a particular population were randomly assigned into two groups, the experimental group and the control group. After analyzing the data, it is known that the learning activity of the students after applying the SSCS learning model has improved towards the better from the first meeting to the fifth meeting, ie 35%, 45%, 55%, 68%, 77%. Based on the hypothesis test obtained ttable = 1.645 and tcount = 2.598 so obtained (2.598> 1.645) at 95% confidence interval. Because tcount > ttable then hypothesis in this research accepted. Thus, students 'math-problem-solving skills taught by SSCS learning models are higher than the students' uneducated mathematical problem-solving skills with SSCS learning modelsKeywords: Problem solving abilities, search, solve, sreate and share (SSCS) learning models
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Rafianti, Isna, Khairida Iskandar, and Lilis Haniyah. "Pembelajaran Search, Solve, Create and Share (SSCS) untuk Meningkatkan Pemahaman Konsep dan Disposisi Matematis Siswa." Journal of Medives : Journal of Mathematics Education IKIP Veteran Semarang 4, no. 1 (2020): 97. http://dx.doi.org/10.31331/medivesveteran.v4i1.980.
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Penelitian ini dilatarbelakangi oleh rendahnya hasil belajar matematika siswa di Indonesia. Hal ini disebabkan oleh beberapa faktor, diantaranya adalah rendahnya kemampuan pemahaman konsep matematis dan didukung oleh rendahnya disposisi matematis siswa yaitu apresiasi terhadap pembelajaran matematika. Salah satu upaya untuk meningkatkan kemampuan pemahaman konsep matematis dan disposisi matematis siswa adalah dengan menggunakan model pembelajaran Search, Solve, Create and Share (SSCS) yang menjadikan siswa mandiri, aktif dan fokus dalam pembelajaran matematika. Penelitian ini bertujuan untuk mengetahui peningkatan kemampuan pemahaman konsep matematis dan disposisi matematis siswa dengan menggunakan model SSCS dalam pembelajaran matematika. Penelitian ini menggunakan metode quasi eksperimen dengan desain non-equivalent control group design. Subyek penelitian ini adalah kelas VIII C (eksperimen) dan VIII D (kontrol) semester 2 SMPN 2 Kota Serang. Instrumen yang digunakan dalam penelitian ini adalah soal tes kemampuan pemahaman konsep matematis dan skala disposisi matematis. Data hasil penelitian ini dianalisis menggunakan uji normalitas, uji homogenitas, uji perbedaan rata-rata. Kesimpulan dari penelitian ini adalah kemampuan pemahaman konsep matematis siswa yang menggunakan model pembelajaran SSCS lebih baik dari siswa yang menggunakan model pembelajaran konvensional. Disposisi matematis yang menggunakan model pembelajaran SSCS memiliki peningkatan yang lebih rendah atau sama dengan siswa yang menggunakan model pembelajaran konvensional. Dengan demikian model pembelajaran SSCS bisa diterapkan untuk meningkatkan kemampuan pemahaman konsep matematis namun kurang efektif dalam peningkatan disposisi matematis siswa SMP.
 Kata kunci: Kemampuan Pemahaman Konsep Matematis, Disposisi Matematis, Model Pembelajaran Search, Solve, Create and Share (SSCS)
 ABSTRACT
 This research is motivated by the low mathematics learning result of students in Indonesia. This is caused by several factors, such as the low ability of understanding mathematical concepts and supported by the low mathematical disposition of students is the appreciation of mathematics learning. One of the efforts to improve the students' understanding of mathematical concepts and mathematical dispositions is by using Search, Solve, Create and Share (SSCS) learning model which makes students self-reliant, active and focused in learning mathematics. This study aims to determine the improvement of the ability to comprehend mathematical concepts and mathematical disposition of students by using SSCS model in mathematics learning. This research uses quasi experimental method with non-equivalent control group design. The subjects of this research are class VIII C (experiment) and VIII D (control) semester 2 SMPN 2 Serang City. The instrument used in this research is the ability to comprehend mathematical concepts and mathematical disposition scale. Data of this study were analyzed using normality test, homogeneity test, two-party test, and one-party test. The conclusion of this research is the ability of understanding mathematical concepts of students using SSCS learning model better than students using conventional learning model. While mathematical dispositions using SSCS learning models have a lower or equal increase with students using conventional learning models. Thus the SSCS learning model can be applied to improve the comprehension of mathematical concepts but less effective in improving mathematical disposition of Junior High School students.
 
 Keywords: Ability to Understand Mathematical Concept, Mathematical Disposition, Search, Solve, Create and Share Learning Model (SSCS)
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Hartanti, Putri Setyo. "KEMAMPUAN PEMECAHAN MASALAH MATEMATIS MELALUI MODEL PEMBELAJARAN SEACRH, SOLVE, CREATE AND SHARE (SSCS) MENGGUNAKAN MEDIA LKPD PADA MATERI PENYAJIAN DATA UNTUK SISWA KELAS VII SMP NEGERI 3 KEPANJEN." JPM : Jurnal Pendidikan Matematika 4, no. 2 (2019): 62. http://dx.doi.org/10.33474/jpm.v4i2.2617.
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Penelitian ini dilatar belakangi oleh rendahnya kemampuan pemecahan masalah matematis siswa. Penelitian ini bertujuan untuk: (1) Mengetahui perbedaan kemampuan pemecahan masalah matematis siswa melalui model pembelajaran SSCS menggunakan media LKPD dengan model model pembelajaran konvensional pada materi Penyajian Data untuk siswa kelas VII SMP Negeri 3 Kepanjen, (2) Mendeskripsikan kemampuan pemecahan masalah matematis siswa melalui model pembelajaran SSCS menggunakan media LKPD pada materi Penyajian Data untuk siswa kelas VII SMP Negeri 3 Kepanjen. Jenis penelitian yang digunakan adalah penelitian kombinasi (mixed methods). Pada tahap pertama, penelitian dilakukan menggunakan pendekatan kuntitatif dengan desain quasy experimental, selanjutnya pada tahap kedua penelitian menggunakan pendekatan kualitatif. Data dalam penelitian tahap pertama ini diperoleh dengan melakukan tes kemampuan pemecahan masalah matematis. Data pada penelitin tahap kedua ini diperoleh dengan metode wawancara dan observasi. Hasil penelitian ini: (1) Hasil analisis data kuantitatif dengan uji hipotesis menggunakan software SPSS 20 diperoleh nilai Sig. = 0.022 < 0.05 maka H0 ditolak atau H1 diterima. Hal ini berarti dapat disimpulkan bahwa terdapat perbedaan kemampuan pemecahan maslaah matematis antara siswa yang diajar dengan model pembelajaraan SSCS menggunakan media LKPD dengan siswa yang diajar dengan model pembelajaran komvensional. (2) Berdasarkan analisis data kualitatif yang diperoleh dari wawancara dapat disimpulkan bahwa siswa yang memiliki kemampuan pemecahan masalah matematis tinggi telah memenuhi semua indikator kemampuan pemecahan masalah matematis, siswa yang memiliki kemampuan pemecahan masalah matematis sedang hanya memenuhi 2 indikator kemampuan pemecahan masalah matematis, dan untuk siswa yang memiliki kamampuan pemecahan masalah matematis rendah hanya memenuhi satu indikator kemampuan pemecahan masalah matematis. Kemampuan pemecahan masalah matematis siswa yang diajar dengan model pembelajaran SSCS menggunakan media LKPD termasuk dalam kategori sedang, yang dapat dilihat dari hasil rata-rata posttest menunjukkan nilai sebesar 79.6.
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Klein, Esther Dominique. "Autonomy and accountability in schools serving disadvantaged communities." Journal of Educational Administration 55, no. 5 (2017): 589–604. http://dx.doi.org/10.1108/jea-06-2016-0065.
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Purpose Increased school autonomy and accountability have been a common denominator of national reforms in otherwise heterogeneous governance systems in Europe and the USA. The paper argues that because schools serving disadvantaged communities (SSDCs) often have lower average performance, they are more often sanctioned or under closer scrutiny, but might also receive more additional resources. The purpose of this paper is to therefore analyze whether SSDCs have more or less autonomy than schools with a more advantageous context in four countries with heterogeneous autonomy and accountability policies. Design/methodology/approach The paper is based on the data from the Programme for International Student Assessment 2012 school and student questionnaires from Finland, Germany, the UK, and the USA. The choice of countries is based on different governance models described by Glatter et al. (2003). The data are used to identify SSDCs and analyze the reported autonomy in resource allocation and curriculum and assessment. Using regression analyses, patterns are analyzed for each country individually. They are then juxtaposed and compared. Differences are related back to the governance models of the respective countries. Findings The results indicate an association between the communities the schools are serving and the autonomy either in the allocation of resources, or the curriculum and assessment. SSDCs appeared to have a little more autonomy than schools with a more advantageous context in Finland, Germany, and the UK, but less autonomy in the USA. The comparison suggests that in the USA, autonomy is rather a reward for schools that have the least amount of need, whereas in the other three countries it could be a result of strategies to improve schools in need. The paper discusses possible explanations in the policies and support structures for SSDCs. Originality/value The effects of increased school autonomy and accountability on student achievement have been discussed at length. How different accountability policies affect the autonomy of schools with the highest needs has so far not been studied. The study can be understood as a first step to unravel this association. Following steps should include in-depth investigations of the mechanisms underlying increased or diminished autonomy for SSDCs, and the consequences for school improvement in these schools.
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Anggriani, Lisa, Sutrimah Sutrimah, and Cahyo Hasanudin. "Analisis Keterampilan Menulis Puisi dengan Menggunakan Kolaborasi Metode SSCS dan Media Audio Visual." Aksara: Jurnal Ilmu Pendidikan Nonformal 6, no. 2 (2020): 201. http://dx.doi.org/10.37905/aksara.6.2.201-212.2020.
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<p>Penelitian ini bertujuan untuk mengetahui puisi yang ditulis oleh siswa kelas X 2 Agama MA ABUDARRIN Kendal Bojonegoro, Indonesia pada pembelajaran kolaborasi metode SSCS dan media audio visual. Penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan deskriptif kualitatif dengan jumlah subjek 34 siswa. Dari 34 siswa selanjutnya peneliti mengambil 5 siswa untuk diwawancarai dengan alasan mereka memiliki kemampuan menulis puisi yang baik sesuai indikator. Teknik pengumpulan data menggunakan metode tes, wawancara, observasi, dan dokumentasi. Data divalidasi dengan menggunakan triangulasi sumber dan triangulasi metode. Teknik analisis data menggunakan metode content analysis dengan dimulai dari 1) reduksi data, 2) penyajian data, dan 3) penarikan simpulan/verifikasi. Hasil penelitian menunjukkan bahwa puisi yang ditulis oleh siswa kelas X 2 Agama MA ABUDARRIN Kendal Bojonegoro, Indonesia sudah mengacu pada struktur puisi menurut Waluyo. Simpulan pada penelitian ini adalah metode SSCS yang berbantukan media audio visual sangat tepat diterapkan pada pembelajaran. Metode SSCS dan media audio visual dapat membuat siswa untuk berfikir kreatif serta dapat menunangkan ide-idenya kedalam bentuk puisi.</p>
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Fitri, Irma, Santi Agustin, Depriwana Rahmi, and Depi Fitraini. "Pengaruh Penerapan Model Pembelajaran Search Solve Create Share (SSCS) terhadap Pemahaman Konsep Matematis ditinjau dari Pengetahuan Awal Siswa Sekolah Menengah Pertama Negeri 1 Kampar Kiri Tengah." Jurnal Cendekia : Jurnal Pendidikan Matematika 2, no. 2 (2018): 42–53. http://dx.doi.org/10.31004/cendekia.v2i2.1.
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Penelitian ini bertujuan untuk menyelidiki ada tidaknya perbedaan Pemahaman Konsep matematis antara siswa yang mengikuti model pembelajaran Search Solve Create Share (SSCS) dengan siswa yang mengikuti model pembelajaran konvensional jika ditinjau dari Pengetahuan Awal siswa kelas VIII SMP N 1 Kampar Kiri Tengah. Penelitian ini merupakan penelitian Quasy Eksperimen yang bertujuan untuk mencari pengaruh perlakuan tertentu dengan cara memberikan perlakuan pada salah satu kelas dan membandingkan hasilnya dengan salah satu kelas yang diberikan perlakuan yang berbeda. Analisis data dilakukan dengan menggunakan uji-t untuk hipotesis 1 dan 2, uji korelasi untuk hipotesis 3, serta anova dua arah untuk hipotesis 4.
 Berdasarkan hasil analisis data dapat diambil kesimpulan bahwa: 1) Terdapat perbedaan pemahaman konsep antara siswa yang mengikuti pembelajaran dengan model pembelajaran SSCS dengan siswa yang mengikuti pembelajaran konvensional; 2) Tidak Terdapat perbedaan pengetahuan awal siswa kelas eksperimen dan kelas kontrol; 3) Terdapat kontribusi yang diberikan pengetahuan awal terhadap pemahaman konsep matematis; 4) Tidak terdapat interaksi antara model pembelajaran SSCS yang ditinjau berdasarkan pengetahuan awal terhadap pemahaman konsep matematis siswa. Dengan demikian secara umum pembelajaran model SSCS berpengaruh terhadap Pemahaman Konsep Matematis yang ditinjau berdasarkan Pengetahuan Awal siswa SMP N 1 Kampar Kiri Tengah.
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Figueiredo, Alcidio Silva, and Luisa Helena Pinto. "Robotizing shared service centres: key challenges and outcomes." Journal of Service Theory and Practice 31, no. 1 (2020): 157–78. http://dx.doi.org/10.1108/jstp-06-2020-0126.
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PurposeThe introduction of robotic process automation (RPA) in shared service centres (SSCs) can hardly be overlooked. This article, therefore, draws on the institutional theory to widen the understanding of its implementation and outcomes regarding people management. Drawing on the lens of the institutional theory and the literature on SSCs and RPA, this study addresses the key challenges and outcomes of robotization.Design/methodology/approachThe study follows a qualitative approach and a purposeful sampling design that collected data from six major SSCs) introducing robotization. Data were collected from semi-structured interviews with service representatives, including RPA project managers. A thematic content analysis was used.FindingsThe introduction of robotics follows mechanisms of coercive, normative and mimetic isomorphism and is effectively replacing workers. So far, this process has been managed through a few reactive people management practices, such as earlier retirements, internal mobility and outsourcing reduction, which warns of future tensions. The findings also show the emergence of new jobs, such as robot developers and robot managers.Originality/valueThe paper contributes to the limited empirical body of research in RPA in SSCs. The study is novel as it is one of the first offering an implementation roadmap for other SSCs and illustrates the positive impact on processes redesign. It also provides empirical evidence on the debate about the potential for service workers' replacement versus tasks augmentation. In the longer term, this study opens new research avenues related to the tensions and contradictions from the progressive institutionalization of robotization in service organizations.
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Guidetti, Giulia, and Cinzia Albanesi. "Senso di comunità. Può bastare per fronteggiare l'emergenza COVID-19 a scuola? Uno studio di un caso su una scuola secondaria di primo grado." PSICOLOGIA DI COMUNITA', no. 1 (June 2021): 81–95. http://dx.doi.org/10.3280/psc2021-001006.
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L'obiettivo dello studio è comprendere la relazione fra SSoC (Senso di Comunità Scolasti-co) e benessere degli studenti in didattica a distanza (DAD), durante la pandemia, e il ruolo delle scelte metodologiche della scuola sulle stesse variabili (benessere e SSoC), in una scuola secondaria di I grado che usa la Didattica per Ambienti di Apprendimento (DADA). Hanno partecipato alla ricerca 70 studenti (mediante questionario e un'intervista di gruppo) e 13 tra docenti e genitori (mediante interviste individuali). La ricerca ha indagato il ruolo della DAD e il suo impatto sulla scuola, sul SSoC e sul benessere psicologico (PWB) e sociale (MHC-SF). Dai risultati emerge l'importanza del SSoC e di pratiche trasformative nel mantenere il be-nessere scolastico, anche in situazioni di emergenza.
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Pratiwi, Karina, Baskoro Adi Prayitno, and Maridi Maridi. "PENGEMBANGAN MODUL BERBASIS MODEL SEARCH SOLVE CREATE SHARE PADA MATERI SISTEM EKSKRESI UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR ANALITIS SISWA KELAS XI MIPA SMA NEGERI 8 SURAKARTA." INKUIRI: Jurnal Pendidikan IPA 7, no. 3 (2018): 438. http://dx.doi.org/10.20961/inkuiri.v7i3.31726.
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<p>Penelitian ini bertujuan untuk: 1) mengetahui karakteristik modul berbasis model <em>Search Solve Create Share</em> (SSCS) pada materi sistem ekskresi untuk meningkatkan kemampuan berpikir analitis siswa, 2) menguji kelayakan modul berbasis model SSCS pada materi sistem ekskresi untuk meningkatkan kemampuan berpikir analitis siswa, dan 3) mengukur keefektifan modul berbasis model SSCS pada materi sistem ekskresi untuk meningkatkan kemampuan berpikir analitis siswa. Metode penelitian mengacu pada sembilan langkah model <em>Research and Development</em> (R &amp; D) dari Borg dan Gall. Analisis data menggunakan deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan: 1) karakteristik modul berbasis model SSCS<em> </em>dikembangkan berdasarkan sintaks model pembelajaran SSCS yang bermuatan indikator-indikator kemampuan berpikir analitis siswa yang divisualisasikan pada tujuan, materi, kegiatan, dan soal evaluasi modul; 2) kelayakan modul siswa dinilai berkualifikasi sangat baik oleh penilaian ahli materi dengan pemenuhan 84,42%; ahli pengembangan modul 96,09%; dan ahli desain dan keterbacaan 100%; kelayakan modul guru dinilai berkualifikasi sangat baik oleh penilaian ahli materi dengan pemenuhan 84,42%; ahli pengembangan modul 92,97%; ahli desain dan keterbacaan 100%; dan berkualifikasi baik oleh penilaian ahli perangkat pembelajaran 75%; rata-rata penilaian praktisi 92,57%; serta rata-rata penilaian siswa 91,88%; 3) keefektifan modul berbasis model SSCS ditunjukkan dengan rerata hasil kemampuan berpikir analitis siswa kelas perlakuan (68,20), lebih tinggi dibanding dengan kelas<em> </em>kontrol (52,50) dan dapat disimpulkan bahwa modul berbasis model SSCS<em> </em>dinyatakan efektif serta dapat digunakan sebagai alternatif bahan ajar di sekolah.</p>
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Dimyati, Ahmad. "ANALISIS KEMAMPUAN KOMUNIKASI MATEMATIS SISWA MELALUI MODEL SSCS PROBLEM SOLVING DENGAN METODE HYPNOTEACHING." SUPERMAT (JURNAL PENDIDIKAN MATEMATIKA) 4, no. 1 (2020): 1–15. http://dx.doi.org/10.33627/sm.v4i1.339.
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Penelitian ini bertujuan mengkaji dan membandingkan perbedaan peningkatan kemampuan komunikasi matematis antara siswa yang memperoleh pembelajaran Model Search, Solve, Create, and Share (SSCS) dengan metode hypnoteaching dengan pembelajaran konvensional, Penelitian ini merupakan penelitian kuasi eksperimen dengan desain penelitian kelompok kontrol non-ekuivalen yang terdiri dari kelas eksperimen yang memperoleh pembelajaran Model SSCS dengan metode hypnoteaching dan kelas kontrol yang memperoleh pembelajaran konvensional. Populasi penelitian ini adalah siswa MTs Negeri di kabupaten Tangerang dengan sampel penelitian siswa kelas VIII di salah satu MTs Negeri di kabupaten Tangerang. Instrumen yang digunakan untuk mengumpulkan data pada penelitian ini terdiri dari instrumen tes kemampuan komunikasi matematis dan lembar observasi. Data yang diperoleh dianalisis menggunakan uji perbedaan rataan yaitu Uji-t dan Mann-Whitney. Hasil penelitian menunjukkan bahwa peningkatan kemampuan komunikasi matematis siswa yang memperoleh pembelajaran Model SSCS dengan metode hypnoteaching lebih baik daripada siswa yang memperoleh pembelajaran konvensional.
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Raudla, Ringa, and Kaide Tammel. "Creating shared service centres for public sector accounting." Accounting, Auditing & Accountability Journal 28, no. 2 (2015): 158–79. http://dx.doi.org/10.1108/aaaj-06-2013-1371.
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Purpose – The purpose of this paper is twofold. First, it aims to contribute to the theoretical discussion on shared service centres (SSCs) for public sector accounting by putting forth a novel typology of different SSCs and their creation modes, and outlining the challenges these specific models are likely to face. Second, it uses the Estonian case study to test the theoretical conjectures. Design/methodology/approach – Since in the Estonian central government different reform models for creating SSCs for public sector accounting have been tried out, the Estonian case offers an opportunity for exploring what the motives behind the creation of different forms of SSCs can be and what kind of challenges reform actors can face when opting for different reform models. The sources of data for the qualitative case study included official documents, media articles and interviews. Findings – The Estonian case study demonstrates that the distinct reform models for creating SSCs in public sector accounting can indeed have different motives and also face various challenges to different degrees. Some challenges, however, are present in all reform models (e.g. difficulties in achieving customer orientation and reduced input to managerial decision making). Originality/value – This paper puts forth a novel typology of public sector SSC reform models and analyses the challenges these different reform models are likely to face. The theoretical contribution and the Estonian case study are valuable for both academics and practitioners analysing or considering the creation of SSCs.
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Narimanpour, Zeinab, Maryam Nazm Bojnordi, and Hatef Ghasemi. "An Efficient In Vitro Culture System To Amplify Spermatogonia Stem Cell Markers." Research in Molecular Medicine 8, no. 3 (2020): 117–24. http://dx.doi.org/10.32598/rmm.8.3.2.
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Introduction: Proliferation of spermatogonial stem cells (SSCs) can be a treatment for infertile men. Here, we design an efficient method based on culturing in the presence of Sertoli cells to improve the expression level of some specific spermatogonia stem cell genes during two weeks post culture. Materials and Methods: Cells were derived from neonatal (2-6 days old) mice testes and were cultured in DMEM medium with FBS. The colonization of cultured SSCs in days 4, 7, and 14 of culture was counted via phase-contrast microscope and Image J software. Methyl thiazolyl tetrazolium (MTT) test was performed to evaluate the viability of cultured SSCs in days 3, 7, and 14 of culture. The expression level and the alteration pattern of specific spermatogonial markers, i.e., Stra8, DAZL, and Piwill2 was examined via real-time polymerase chain reaction (PCR) during two weeks post culture. Results: The number and the diameters of colonies showed a significant increase in cultured cells. MTT results proved the higher viability of testicular cells during the culture period. The results of ALP staining detected a positive reaction in spermatogonia colonies. Real-time PCR data showed that culturing SSCs in the presence of interstitial cells of the testis, amplified the level and alteration pattern of specific spermatogonia stem cells genes beneficial in the enrichment of SSCs propagation. Conclusion: Providing a similar culture environment to testicular niche increases viability, forms SSCs colonies, and regulates the level and alteration pattern of spermatogonia stem cell genes.
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Malekzadeh Shafaroudi, Ali, Pegah Nasiri, and Azam Nahvi. "Nickel Sensitivity in Children Due to Using Stainless Steel Crowns: A Narrative Review." Journal of Pediatrics Review 9, no. 2 (2021): 145–52. http://dx.doi.org/10.32598/jpr.9.2.870.2.
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Context: Stainless Steel Crowns (SSC) are stable and durable restorations and a valuable technique in repairing deciduous teeth with extensive caries. Nickel and chromium are the main composing elements of SSCs, i.e. released in the oral environment; they can cause allergic reactions, especially in nickel-sensitive children. The symptoms of these reactions include gingival edema and the loss of alveolar bone. Evidence Acquisition: The required data used in our review were searched from articles published until 2020 and collected from online databases, including Scopus, PubMed, Google Scholar, and Science Direct, using “Nickel, Allergy, and SSCs” keywords. Articles concerning SSCs and their application, nickel allergy released from crowns, and their symptoms were included in this study. After the abstract screening, we recalled relevant studies for full-text review. Results: We are exposed to nickel every day in various forms; some individuals present hypersensitivity reactions when exposed to the slightest amounts of this metal. Nickel is a base metal and among the elements used in SSCs. Nickel is released from SSCs during the corrosion process in the oral environment. Excessively released nickel ions cause chronic fatigue syndrome, sensitive lymph nodes, muscle aches, and headaches. Conclusions: The amount of nickel released from SSCs is less than the number of other sources; thus, the immunological reactions of a large percentage of the population to this excess amount of nickel ions in the bloodstream are normal and cause no severe problems.
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Lam, N. T., D. Gratadour, D. Rouan, and L. Grosset. "High angular resolution study of the super star cluster population in IRAS 17138−1017." Astronomy & Astrophysics 639 (July 2020): A28. http://dx.doi.org/10.1051/0004-6361/202037755.
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Aims. Currently, the global characteristics and evolution of super star clusters (SSCs) are not well understood, due to the large distances to their host galaxies. We aim to study the population of SSCs in IRAS 17138-1017, a luminous infrared galaxy (LIRG), in terms of age, extinction, mass, and luminosity distribution. Methods. We analyzed imaging data in the near-infrared from the GeMS/GSAOI instrument on the Gemini telescope and generated simulations with the radiative transfer code MontAGN. The extraction of SSCs from the images and their photometry in J, H, and Ks allowed us to derive color-color and color-magnitude diagrams. Comparison with a theoretical stellar evolutionary track gives a first hint into the extinction towards each SSC, as well as their ages, despite some degeneracy between those two quantities. Spectra given by our radiative transfer code MontAGN, which includes dust emission, also provide insightful predictions and comparisons. Results. We detect with a fair degree of confidence 54 SSCs of mKs between 16 mag and 21 mag with a median instrumental uncertainty of 0.05 mag. When plotted on a color–color diagram and a color–magnitude diagram, it appears that most of the sources are very much extinct with respect to an intrinsic theoretical evolutionary track. Once de-reddened, the colors point unambiguously to two distinct and very recent starburst episodes at 2.8 and 4.5 Myr. While the SSCs in the 4.5 Myr starburst are distributed along the spiral arms, the 2.8 Myr SSCs are concentrated in the central region. The luminosity and mass functions present a classical power-law behavior, although with shallower slopes than generally observed in LIRGs. Comparison with radiative transfer simulations shows that, the dust thermal emission and scattered light are negligible and could not explain the few very red SSCs that could not be de-reddened safely.
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Sait, Afrah S., Shalom S. Patole, Kathryn Dzintars, Sara E. Cosgrove, and Seema Mehta Steinke. "205. Rectal Stool Surveillance Cultures to Guide Empiric Antibiotic Therapy in Patients with Hematologic Malignancies with or without Hematopoietic Stem Cell Transplantation." Open Forum Infectious Diseases 7, Supplement_1 (2020): S106. http://dx.doi.org/10.1093/ofid/ofaa439.249.
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Abstract Background Patients with hematologic malignancies (HM) or hematopoietic stem cell transplant (HSCT) commonly receive broad-spectrum antimicrobials, often leading to the development of multidrug resistant organisms (MDRO). At our institution, rectal stool surveillance cultures (SSC) are done weekly on admitted adult patients with HMs or HSCT. The objective of this study is to determine the role of SSCs in predicting the development of a sterile site infection (StSI) with the same MDRO as identified in the SSC. Methods We retrospectively evaluated StSIs (blood, CSF, sputum/respiratory, pleural fluid, and urine) and SSC data from 242 adult patients admitted to the adult oncology ward at a large academic tertiary care center from 6/1/2017 to 2/28/2019. Demographics, SSC data, and StSIs in a 3-month period following the last SSC for each patient were collected from electronic medical records. SSCs were cultured on HardyCHROM ESBL™ media. MDRO similarity between SSC and StSI was determined by comparing susceptibility profiles. JMPÒ Pro 14.3.0 and RStudio were used for statistical analyses. Results Two hundred forty-two patients yielded 732 SSCs. We eliminated SSCs with incomplete (&lt; 3 months of follow up) data. Thus, 579 SSCs were included in the analyses. 64% of patients were male. Leukemias (55.4%), lymphomas (21.9%), and multiple myeloma (10.3%) were the most common HMs. HSCT recipients comprised 50.4%. SSCs were positive for a MDRO in 251 cases (vancomycin-resistant enterococci, 52.2%; extended-spectrum beta-lactamase (ESBL) producing organisms, 22.2%; and carbapenamase producing organisms, 4.4%). There were 54 StSIs documented where the MDRO was the same as the SSC MDRO. The NPV of the SSC was 95.1% (95%CI 0.93,0.97). The positive likelihood ratio of the SSC was 2.5 (95%CI 2.07,3.02). Conclusion Our results suggest that a negative SSC is associated with a lower probability of identifying a StSI with an MDRO. Clinically, this can be useful in providing the opportunity to judiciously guide antimicrobial therapy, thereby avoiding the unnecessary usage of broad-spectrum antimicrobials when no MDRO is identified in the SSC. Disclosures All Authors: No reported disclosures
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Gale, Fred, Francisco Ascui, and Heather Lovell. "Sensing Reality? New Monitoring Technologies for Global Sustainability Standards." Global Environmental Politics 17, no. 2 (2017): 65–83. http://dx.doi.org/10.1162/glep_a_00401.
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In the 1990s, civil society organizations partnered with business to “green” global supply chains by setting up formal sustainability standard-setting organizations (SSOs) in sectors including organic food, fair trade, forestry, and fisheries. Although SSOs have withstood the long-standing allegations that they are unnecessary, costly, nondemocratic, and trade-distorting, they must now respond to a new challenge, arising from recent developments in technology. Conceived in the pre-Internet era, SSOs are discovering that verification systems that utilize annual, expert-led, low-tech field audits are under pressure from new information and communication technologies that collect, aggregate, interpret, and display open-source “Big Data” in almost real time. Drawing on the concept of governmentality and on interviews with experts in sustainability certification and natural capital accounting, we argue that while these technological developments offer many positive opportunities, they also enable competing alternatives to the prevailing “truth” or governing rationality about what is happening “on the ground,” which is of critical existential importance to SSOs as guarantors of trust in claims about sustainable production. While SSOs are not helpless in the face of this challenge, we conclude that they will need to do more than take incremental action: rather, they should respond actively to the disintermediation challenge from new virtual monitoring technologies if they are to remain relevant in the coming decade.
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Saniyah, Millatus. "EFEKTIVITAS MODEL PEMBELAJARAN MMP DIPADU DENGAN STRATEGI SSCS TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA MATERI KUBUS DAN BALOK SMP NEGERI 5 BATANG." Delta: Jurnal Ilmiah Pendidikan Matematika 5, no. 2 (2018): 1. http://dx.doi.org/10.31941/delta.v5i2.468.
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<p>Penelitian ini bertujuan untuk mengetahui keefektifan model pembelajaran MMP dipadu dengan strategi SSCS terhadap kemampuan pemecahan masalah siswa materi Kubus dan Balok. Penelitian ini merupakan penelitian kuantitatif eksperimental dengan desain penelitian berupa <em>quasi eksperimental</em> bentuk <em>the nonequivalent posttest-only</em> <em>control group design</em>. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMP Negeri 5 Batang tahun pelajaran 2016/2017. Melalui teknik <em>cluster random sampling </em>terpilih 2 kelas sampel yaitu kelas VIII A sebagai kelas eksperimen dengan model pembelajaran MMP dipadu dengan strategi SSCS dan kelas VIII D sebagai kelas kontrol dengan strategi pembelajaran ekspositori. Variabel dalam penelitian ini adalah model pembelajaran MMP dipadu dengan strategi SSCS (variabel bebas) dan kemampuan pemecahan masalah (variabel terikat). Untuk memperoleh data digunakan metode dokumentasi dan tes. Data dianalisis dengan menggunakan uji ketuntasan klasikal dan uji beda rata-rata. Hasil penelitian menunjukkan: (1) , kemampuan pemecahan masalah siswa kelas eksperimen dapat mencapai ketuntasan; dan (2) kemampuan pemecahan masalah antara siswa kelas eksperimen lebih baik dari kemampuan pemecahan masalah siswa kelas kontrol. Berdasarkan kedua hasil tersebut dapat disimpulkan bahwa penerapan model pembelajaran MMP dipadu dengan strategi SSCS mencapai kriteria efektif terhadap kemampuan pemecahan masalah siswa.</p>
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Mambwe, Mwewa, Erastus M. Mwanaumo, Wellington D. Thwala, and Clinton O. Aigbavboa. "Evaluating Occupational Health and Safety Management Strategy Success Factors for Small-Scale Contractors in Zambia." Sustainability 13, no. 9 (2021): 4696. http://dx.doi.org/10.3390/su13094696.
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Small-scale contractors (SSCs) require management strategies in implementing occupational health and safety (OH&S) performance at projects to reduce accidents, injuries, fatalities and diseases. Management strategy success factors have been acknowledged to be of great benefit in improving in OH&S performance. Hence, the study sought to assess the management strategy success factors for the improvement of OH&S performance by SSCs in Zambia’s electricity industry. Using quantitative methods, data was collected using a survey questionnaire from 246 respondents representing firm owners, managers, project managers and OH&S representatives at electricity industry projects at 70.3% response rate. Descriptive and inferential statistics were adopted as methods of data analysis using exploratory factor analysis. After analysis, the success factors were clustered into three construct categories within OH&S performance namely, compliance and workplace processes, policy and human resource development, and leadership and structure significant values ranging from 0.513 to 0.972. The independent reliability was tested using the Cronbach Alpha coefficient. The study exposed management strategy success factors are well recognised by most SSCs and contributed to the body of knowledge in this mastery by introducing three success factors for OH&S performance. It is recommended that these factors be adopted and considered to improve OH&S performance management by SSCs in the electricity industry in Zambia.
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Beaumet, Julien, Michel Déqué, Gerhard Krinner, Cécile Agosta, and Antoinette Alias. "Effect of prescribed sea surface conditions on the modern and future Antarctic surface climate simulated by the ARPEGE atmosphere general circulation model." Cryosphere 13, no. 11 (2019): 3023–43. http://dx.doi.org/10.5194/tc-13-3023-2019.
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Abstract. Owing to increase in snowfall, the Antarctic Ice Sheet surface mass balance is expected to increase by the end of the current century. Assuming no associated response of ice dynamics, this will be a negative contribution to sea-level rise. However, the assessment of these changes using dynamical downscaling of coupled climate model projections still bears considerable uncertainties due to poorly represented high-southern-latitude atmospheric circulation and sea surface conditions (SSCs), that is sea surface temperature and sea ice concentration. This study evaluates the Antarctic surface climate simulated using a global high-resolution atmospheric model and assesses the effects on the simulated Antarctic surface climate of two different SSC data sets obtained from two coupled climate model projections. The two coupled models from which SSCs are taken, MIROC-ESM and NorESM1-M, simulate future Antarctic sea ice trends at the opposite ends of the CMIP5 RCP8.5 projection range. The atmospheric model ARPEGE is used with a stretched grid configuration in order to achieve an average horizontal resolution of 35 km over Antarctica. Over the 1981–2010 period, ARPEGE is driven by the SSCs from MIROC-ESM, NorESM1-M and CMIP5 historical runs and by observed SSCs. These three simulations are evaluated against the ERA-Interim reanalyses for atmospheric general circulation as well as the MAR regional climate model and in situ observations for surface climate. For the late 21st century, SSCs from the same coupled climate models forced by the RCP8.5 emission scenario are used both directly and bias-corrected with an anomaly method which consists in adding the future climate anomaly from coupled model projections to the observed SSCs with taking into account the quantile distribution of these anomalies. We evaluate the effects of driving the atmospheric model by the bias-corrected instead of the original SSCs. For the simulation using SSCs from NorESM1-M, no significantly different climate change signals over Antarctica as a whole are found when bias-corrected SSCs are used. For the simulation driven by MIROC-ESM SSCs, a significant additional increase in precipitation and in winter temperatures for the Antarctic Ice Sheet is obtained when using bias-corrected SSCs. For the range of Antarctic warming found (+3 to +4 K), we confirm that snowfall increase will largely outweigh increases in melt and rainfall. Using the end members of sea ice trends from the CMIP5 RCP8.5 projections, the difference in warming obtained (∼ 1 K) is much smaller than the spread of the CMIP5 Antarctic warming projections. This confirms that the errors in representing the Southern Hemisphere atmospheric circulation in climate models are also determinant for the diversity of their projected late 21st century Antarctic climate change.
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Ghalenoei, E., M. A. Sharifi, and M. Hasanlou. "ESTIMATING AND FUSING OPTICAL FLOW, GEOSTROPHIC CURRENTS AND SEA SURFACE WIND IN THE WATERS AROUND KISH ISLAND." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-1-W5 (December 11, 2015): 221–26. http://dx.doi.org/10.5194/isprsarchives-xl-1-w5-221-2015.
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The aim of this study is calculation of sea surface currents (SSCs) which are estimated from satellite data sets and processed with the variance component estimation (VCE) algorithm to check role of each data set, in fused surface currents (FSCs). The satellite data used in this study are sea surface temperature (SST), satellite altimetry data and sea surface wind (SSW) that plays the important role to make the SSCs and is measured by Ascat satellite. We use optical flow (OF) method (Horn-Schunck algorithm) to extract sea surface movements from sequential SST imageries; in addition, geostrophic currents (GCs) are estimated by satellite altimetry data like sea surface height (SSH). Combining these data sets, has its pros and cons, the OF results are so dense and precise due to high spatial resolution of MODIS data (SST), but sometimes cloud covering over the sea, does not allow the MODIS sensor to measure the SST. In contrast the SST data, the altimetry data have poor spatial resolution and the GCs are not able to determine small scale SSCs. The VCE algorithm shows variances of our data sets and it can be shown their correlations with themselves and with the FSCs. We also calculate angular differences between FSCs and OF, GCs and SSW, and plot distributions of these angular differences. We discover that, the OF and SSW are homolographic, but OF and GCs are accordant to each other.
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Randriamanakoto, Zara, and Petri Väisänen. "Super Star Cluster Luminosity Functions in Interacting Luminous Infrared Galaxies." Proceedings of the International Astronomical Union 6, S277 (2010): 37–40. http://dx.doi.org/10.1017/s1743921311022423.
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AbstractYoung and massive super star clusters (SSCs) are found whenever very active star formation is going on, such as that in interacting Luminous Infrared Galaxies (LIRGs). From a deep NIR adaptive optics imaging survey, we present thus far the first K-band SSC luminosity functions (LFs) in these types of galaxies, and also a relation between the brightest SSC and the global SFR of the galaxy. Based on the derived LFs, one can constrain the cluster initial mass function (CIMF) and study the formation and evolution of SSCs. Our preliminary results are in disagreement with theoretical expectations which suggest that the SSC LF should be well fitted by a single power-law with an index of −2. We find power-law indexes of ~−1.5, shallower than the expected ones. Taken at face value, our results appear to support the concept that the CIMF is mass-dependent, not universal, which will be studied in more detail by mass-modelling of the SSCs. The data-set will also allow us to estimate the fraction of total star formation originating in the SSCs over a range of galaxy types.
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Bazaz, Safa, Tõnis Lehto, Rahel Tops, et al. "Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo." Biomedicines 9, no. 8 (2021): 1046. http://dx.doi.org/10.3390/biomedicines9081046.
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Splice-switching therapy with splice-switching oligonucleotides (SSOs) has recently proven to be a clinically applicable strategy for the treatment of several mis-splice disorders. Despite this, wider application of SSOs is severely limited by the inherently poor bioavailability of SSO-based therapeutic compounds. Cell-penetrating peptides (CPPs) are a class of drug delivery systems (DDSs) that have recently gained considerable attention for improving the uptake of various oligonucleotide (ON)-based compounds, including SSOs. One strategy that has been successfully applied to develop effective CPP vectors is the introduction of various lipid modifications into the peptide. Here, we repurpose hydrocarbon-modified amino acids used in peptide stapling for the orthogonal introduction of hydrophobic modifications into the CPP structure during peptide synthesis. Our data show that α,α-disubstituted alkenyl-alanines can be successfully utilized to introduce hydrophobic modifications into CPPs to improve their ability to formulate SSOs into nanoparticles (NPs), and to mediate high delivery efficacy and tolerability both in vitro and in vivo. Conclusively, our results offer a new flexible approach for the sequence-specific introduction of hydrophobicity into the structure of CPPs and for improving their delivery properties.
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Lu, Chuncheng, Yan Zhang, Yufeng Qin, et al. "Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis." Journal of Medical Genetics 58, no. 1 (2020): 56–65. http://dx.doi.org/10.1136/jmedgenet-2019-106598.
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BackgroundInfertility affects approximately 15% of couples worldwide with male infertility being responsible for approximately 50% of cases. Although accumulating evidence demonstrates the critical role of the X chromosome in spermatogenesis during the last few decades, the expression patterns and potential impact of the X chromosome, together with X linked genes, on male infertility are less well understood.MethodsWe performed X chromosome exome sequencing followed by a two-stage independent population validation in 1333 non-obstructive azoospermia cases and 1141 healthy controls to identify variant classes with high likelihood of pathogenicity. To explore the functions of these candidate genes in spermatogenesis, we first knocked down these candidate genes individually in mouse spermatogonial stem cells (SSCs) using short interfering RNA oligonucleotides and then generated candidate genes knockout mice by CRISPR-Cas9 system.ResultsFour low-frequency variants were identified in four genes (BCORL1, MAP7D3, ARMCX4 and H2BFWT) associated with male infertility. Functional studies of the mouse SSCs revealed that knocking down Bcorl1 or Mtap7d3 could inhibit SSCs self-renewal and knocking down Armcx4 could repress SSCs differentiation in vitro. Using CRISPR-Cas9 system, Bcorl1 and Mtap7d3 knockout mice were generated. Excitingly, Bcorl1 knockout mice were infertile with impaired spermatogenesis. Moreover, Bcorl1 knockout mice exhibited impaired sperm motility and sperm cells displayed abnormal mitochondrial structure.ConclusionOur data indicate that the X-linked genes are associated with male infertility and involved in regulating SSCs, which provides a new insight into the role of X-linked genes in spermatogenesis.
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Mahlke, M., H. Bouy, B. Altieri, et al. "Mining the Kilo-Degree Survey for solar system objects." Astronomy & Astrophysics 610 (February 2018): A21. http://dx.doi.org/10.1051/0004-6361/201730924.
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Context. The search for minor bodies in the solar system promises insights into its formation history. Wide imaging surveys offer the opportunity to serendipitously discover and identify these traces of planetary formation and evolution. Aim. We aim to present a method to acquire position, photometry, and proper motion measurements of solar system objects (SSOs) in surveys using dithered image sequences. The application of this method on the Kilo-Degree Survey (KiDS) is demonstrated. Methods. Optical images of 346 deg2 fields of the sky are searched in up to four filters using the AstrOmatic software suite to reduce the pixel to catalog data. The SSOs within the acquired sources are selected based on a set of criteria depending on their number of observation, motion, and size. The Virtual Observatory SkyBoT tool is used to identify known objects. Results. We observed 20 221 SSO candidates, with an estimated false-positive content of less than 0.05%. Of these SSO candidates, 53.4% are identified by SkyBoT. KiDS can detect previously unknown SSOs because of its depth and coverage at high ecliptic latitude, including parts of the Southern Hemisphere. Thus we expect the large fraction of the 46.6% of unidentified objects to be truly new SSOs. Conclusions. Our method is applicable to a variety of dithered surveys such as DES, LSST, and Euclid. It offers a quick and easy-to-implement search for SSOs. SkyBoT can then be used to estimate the completeness of the recovered sample.
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Fatiya, Maulidya Rizqa, Partaya Partaya, and Nur Kusuma Dewi. "PENERAPAN MODEL SEARCH, SOLVE, CREATE, SHARE (SSCS) PADA MATERI PERUBAHAN LINGKUNGAN UNTUK MENINGKATKAN HASIL BELAJAR DAN AKTIVITAS SISWA DI SM." Bioma : Jurnal Ilmiah Biologi 8, no. 1 (2019): 291–303. http://dx.doi.org/10.26877/bioma.v8i1.4685.
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Kualitas pembelajaran dipengaruhi oleh model pembelajaran yang digunakan. Model pembelajaran berbasis masalah salah satunya adalah Search, Solve, Create, Share (SSCS) dengan melibatkan siswa untuk belajar dari objek nyata di lingkungan sekitar. Tujuan penelitian ini untuk mengetahui penerapan model pembelajaran SSCS pada materi perubahan lingkungan dalam meningkatkan hasil belajar dan aktivitas siswa. Desain penelitian yang digunakan adalah Nonequivalent Control Group Design. Populasi dalam penelitian ini yaitu seluruh siswa kelas X SMA Negeri 1 Kota Tegal. Sampel penelitian yaitu kelas X MIA 6 dan X MIA 7 yang ditentukan secara purposive sampling. Teknik pengumpulan data menggunakan tes, observasi, angket dan wawancara. Hasil penelitian menunjukkan bahwa kelas eksperimen memiliki hasil belajar dan aktivitas siswa yang lebih tinggi dibandingkan kelas kontrol. Ketuntasan klasikal untuk hasil belajar serta aktivitas siswa semuanya mencapai indikator keberhasilan pembelajaran yaitu sebesar ≥75% dari jumlah siswa mendapatkan nilai ≥75. Hasil uji N-Gain menunjukkan peningkatan dalam kriteria sedang yaitu kelas eksperimen sebesar 0,69 dan kelas kontrol sebesar 0,60. Tanggapan siswa dengan kriteria sangat baik sebesar 93,93% dan baik sebesar 6,06%. Guru juga memberikan tanggapan positif terhadap pembelajaran. Berdasarkan hasil analisis dapat disimpulkan bahwa pembelajaran dengan menerapkan model SSCS pada materi perubahan lingkungan berpengaruh terhadap hasil belajar dan aktivitas siswa di SMA. Kata kunci: hasil belajar, model Search, Solve, Create, Share (SSCS), aktivitas siswa
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Boyer, Alexandre, Xiangfan Zhang, Adrien Levasseur, et al. "Constitutive activation of CTNNB1 results in a loss of spermatogonial stem cell activity in mice." PLOS ONE 16, no. 5 (2021): e0251911. http://dx.doi.org/10.1371/journal.pone.0251911.
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Spermatogenesis requires that a careful balance be maintained between the self-renewal of spermatogonial stem cells (SSCs) and their commitment to the developmental pathway through which they will differentiate into spermatozoa. Recently, a series of studies employing various in vivo and in vitro models have suggested a role of the wingless-related MMTV integration site gene family/beta-catenin (WNT/CTNNB1) pathway in determining the fate of SSCs. However, conflicting data have suggested that CTNNB1 signaling may either promote SSC self-renewal or differentiation. Here, we studied the effects of sustained CTNNB1 signaling in SSCs using the Ctnnb1tm1Mmt/+; Ddx4-CreTr/+ (ΔCtnnb1) mouse model, in which a stabilized form of CTNNB1 is expressed in all germ cells. ΔCtnnb1 mice were found to have reduced testis weights and partial germ cell loss by 4 months of age. Germ cell transplantation assays showed a 49% reduction in total functional SSC numbers in 8 month-old transgenic mice. In vitro, Thy1-positive undifferentiated spermatogonia from ΔCtnnb1 mice formed 57% fewer clusters, which was associated with decreased cell proliferation. A reduction in mRNA levels of genes associated with SSC maintenance (Bcl6b, Gfra1, Plzf) and increased levels for markers associated with progenitor and differentiating spermatogonia (Kit, Rarg, Sohlh1) were detected in these cluster cells. Furthermore, RNAseq performed on these clusters revealed a network of more than 900 genes regulated by CTNNB1, indicating that CTNNB1 is an important regulator of spermatogonial fate. Together, our data support the notion that CTNNB1 signaling promotes the transition of SSCs to undifferentiated progenitor spermatogonia at the expense of their self-renewal.
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Wahyuningsih, Dewi, Abdullah Abdullah, and Herdini Herdini. "Pengembangan Lembar Kegiatan Peserta Didik (LKPD) Berbasis Search, Solve, Create and Share (SSCS) Pada Materi Asam Dan Basa Untuk Kelas XI SMA/MA." Jurnal Pijar Mipa 15, no. 5 (2020): 497. http://dx.doi.org/10.29303/jpm.v15i5.1479.
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Penelitian ini bertujuan untuk mengembangkan Lembar Kegiatan Peserta Didik (LKPD) Berbasis SSCS pada Materi Asam dan Basa. Penelitian dirancang mengacu pada desain penelitian dan pengembangan (R & D) dengan model pengembangan Plomp.Instrumen pengumpulan data yang digunakan berupa lembar validasi dan angket respon pengguna. Validasi dilakukan oleh 3 orang validator dan diperoleh hasil validasi pada aspek kelayakan isi, karakteristik SSCS, kebahasaan, sajian dan kegrafisan berturut-turut yaitu sebesar 92,71%, 91,67%, 96,67%, 97,22% dan 95,83% dengan kategori valid. Uji one to one dilakukan pada 6 orang peserta didik, LKPD mampu dikerjakan oleh peserta didik dengan baik, diperoleh waktu pengerjaan LKPD serta saran dan komentar peserta didik terhadap LKPD. Hasil penilaian LKPD dari sisi pengguna yaitu 20 orang peserta didik diperoleh persentase sebesar 90,45% dan penilaian oleh 2 orang guru kimia diperoleh persentase sebesar 93,42% dengan kriteria sangat baik, artinya LKPD yang telah dikembangkan layak digunakan dalam pembelajaran.Kata Kunci : Lembar Kegiatan Peserta Didik (LKPD), SSCS, Asam dan Basa
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Simcoe, Timothy. "Standard Setting Committees: Consensus Governance for Shared Technology Platforms." American Economic Review 102, no. 1 (2012): 305–36. http://dx.doi.org/10.1257/aer.102.1.305.
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Voluntary Standard Setting Organizations (SSOs) use a consensus process to create new compatibility standards. Practitioners have suggested that SSOs are increasingly politicized and perhaps incapable of producing timely standards. This article develops a simple model of standard setting committees and tests its predictions using data from the Internet Engineering Task Force, an SSO that produces many of the standards used to run the Internet. The results show that an observed slowdown in standards production between 1993 and 2003 can be linked to distributional conflicts created by the rapid commercialization of the Internet. (JEL C78, L15, L86)
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Susmiyarti, Susmiyarti, Muhammad Farid, and Afrizal Mayub. "Hubungan antara tekanan darah dan gula darah dengan kemampuan kognitif siswa pada pembelajaran fisika melalui model pembelajaran search, solve, create, and share (sscs) di SMA 4 Bengkulu Utara." PENDIPA Journal of Science Education 3, no. 3 (2019): 132–41. http://dx.doi.org/10.33369/pendipa.3.3.132-141.
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ABSTRACT [The Relationship Between Blood Pressure and Blood Sugar with the Cognitive Ability of Students in Physics Learning Through the Search, Solve, Create and Share (SSCS) Learning Model at SMA 4 Bengkulu Utara]. The purpose of this study is to describe the correlation of blood pressure and blood sugar with student achievement in physics learning through the SSCS learning model at SMAN 4 North Bengkulu. The research method is descriptive-analytic with a cross-sectional study approach. From the results of the blood pressure correlation test and student achievement through the SSCS learning model, it was found that p = 0.828> 0.05, which means that the null hypothesis was accepted, that blood pressure did not have a significant relationship with learning achievement. Furthermore, the value of r = 0.022 which has a relationship with the category is very weak. rom the results of the correlation test of blood sugar and student achievement through the SSCS learning model, it was found that p = 0.932> 0.05 which means that the null hypothesis is accepted, that blood sugar does not have a significant relationship with learning achievement. Furthermore, the r value = 0.134 which has a relationship with a very weak category. So from the results of the analysis above, it can be concluded that there is no relationship between blood pressure and blood sugar with physics learning achievement of students of class X MIPA and XI MIPA at SMAN 4 North Bengkulu. Keywords: Blood Pressure; Blood Sugar; Learning Achievement; Physics Learning; SSCS Model. (Received July 9, 2019; Accepted August 5, 2019; Published October 16, 2019) ABSTRAKTujuan penelitian ini yaitu mendeskripsikan hubungan antara tekanan darah dan gula darah dengan kemampuan kognitif siswa pada pembelajaran fisika melalui model pembelajaran SSCS di SMAN 4 Bengkulu Utara. Metode penelitian ini yaitu deskriptif-analitik dengan melalui metode korelasi. Dari hasil uji korelasi tekanan darah dan prestasi belajar siswa melalui model pembelajaran SSCS yang diajarkan secara tidak langsung kepada siswa selama pengambilan data tekanan darah dan gula darah siswa didapat bahwa p=0,828>0,05 yang artinya hipotesis nol diterima yaitu tekanan darah tidak memiliki hubungan yang signifikan dengan kemampuan kognitif. Selanjutnya, nilai r=0,022 yang memiliki hubungan dengan kategori sangat lemah antara tekanan darah dan kemampuan kognitif siswa. Dari hasil uji korelasi gula darah dan kemampuan kognitif siswa melalui model pembelajaran SSCS didapat bahwa p=0,932>0,05 yang artinya hipotesis nol diterima yaitu gula darah tidak memiliki hubungan yang signifikan dengan kemampuan kognitif. Selanjutnya, nilai r=0,134 yang memiliki hubungan dengan kategori sangat lemah. Sehingga dari hasil analisis di atas, dapat disimpulkan bahwa tidak ada hubungan antara tekanan darah dan gula darah dengan kemampuan kognitif fisika siswa kelas X MIPA dan XI MIPA di SMAN 4 Bengkulu Utara. Kata kunci: Tekanan Darah; Gula Darah; Kemampuan kognitif; Pembelajaran Fisika; Model SSCS
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Zahdan, Badia A., Aniko Szabo, Cesar D. Gonzalez, Elaye M. Okunseri, and Christopher E. Okunseri. "Survival Rates of Stainless Steel Crowns and Multi-Surface Composite Restorations Placed by Dental Students in a Pediatric Clinic." Journal of Clinical Pediatric Dentistry 42, no. 3 (2018): 167–72. http://dx.doi.org/10.17796/1053-4628-42.3.1.
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Purpose: This study examined survival rates of multi-surface composite restorations and stainless steel crowns (SSCs) placed by students in a pediatric dental clinic as well as the length of time it takes for restorations to be replaced with stainless steel crowns. Study design: Data from electronic dental records for all children with at least one 2-surface composite restorations or SSCs on a primary first or second molar from January 1, 2007 to September 30, 2015 were analyzed. The primary outcome was the time to a new restoration or SSC on the same tooth, with time to a crown as a secondary outcome. Descriptive statistics were obtained and the cumulative incidence of the event of interest was estimated using 95% confidence intervals and compared between groups using Fine-Gray regression. Results: A total of 6,288 teeth from 2,044 children were analyzed. Three years after the initial procedure, 1.5% of SSCs and 21% of 2 and 3 surface composite restorations failed and needed a replacement (Hazard Ratio [HR]= 14; 95% Confidence interval [CI] 9–22, p&lt;0.001). Also, 6.8% of composite restorations needed replacement with SSCs' (HR=4; 95% CI: 3–7). Conclusions: The study demonstrates that stainless steel crowns had a higher survival rate than multi-surface composite resins placed by students at a pediatric dental clinic in primary molars of children.