Academic literature on the topic 'Stability constant of thiocyanic acid'

With a constant increasing in the health expenses and the aggravation of the global economic situation, managing costs and resources in healthcare is nowadays an essential point in the management of hospitals. The goal of this work is to apply clustering techniques to data collected in real-time about readmitted patients in Intensive Care Units in order to know some possible features that affect readmissions in this area. By knowing the common characteristics of readmitted patients it will be possible helping to improve patient outcome, reduce costs and prevent future readmissions. In this study, it was followed the Stability and Workload Index for Transfer (SWIFT) combined with the results of clinical tests for substances like lactic acid, leucocytes, bilirubin, platelets and creatinine. Attributes like sex, age and identification if the patient came from the chirurgical block were also considered in the characterization of potential readmissions. In general, all the models presented very good results being the Davies-Bouldin index lower than 0.82, where the best index was 0.425.

We present here the first report of the pressure dependence of pressure-jump relaxation kinetics for protein folding transitions. We have studied the relaxation kinetics for the unfolding/refolding of wild-type Staphylococcal nuclease and have found that the relaxation kinetics observed at high pressure are much slower than those observed by pH or denaturant jumps at atmospheric pressure. This indicates that these processes have large, positive values for the activation volumes, most likely stemming from exclusion of solvent from a transition state that is less well packed than the native state. We examined the pressure-jump relaxation kinetics of three single-site mutations in nuclease that lead to alterations in the interactions between the two domains of the protein and changes in the equilibrium constant for isomerization of the lysine-116 to proline 117 peptide bond away from the cis form that predominates in the wild-type enzyme. At comparable pressures, the relaxation times for these mutants were significantly shorter than those observed for the wild type, indicating lower values of the activation volumes. We propose that these mutations cause a decrease in the cooperativity of the unfolding of the two domains, leading to a decrease in the degree of solvent exclusion at the rate-limiting step. The mechanism by which a particular amino acid sequence determines the fold and stability of globular proteins remains one of the most interesting and important unresolved issues in biophysical chemistry. The approaches to increasing our understanding of this phenomenon typically have involved perturbation of the proteins by chemical means or by temperature extremes. The equilibrium or time-dependent responses to these perturbations are then monitored (using a spectroscopic signal, activity, or some other observable) to extract the energetic or kinetic aspects of the unfolding or refolding transitions. Another means of perturbing the system is to modify the protein itself, either chemically or by site-directed mutagenesis, and to assess the effects of modification on the equilibrium or kinetic folding or refolding profiles. This approach has generated a great deal of information about small globular proteins that denature reversibly.

Many forms of electronic equipment, of necessity, must be located in an outdoor environment. Such equipment in typical form may be battery packs or telecom-equipment. It is essential that these facilities be protected from a wide range of ambient temperatures and solar radiation. To this end, cabinet enclosures with proper thermal management have been developed to house such electronic equipment in a highly weather tight manner, especially for battery cabinet. Often the batteries are of a lead-acid construction which is known to be adversely affected by temperature extremes in terms of battery

A study has been undertaken to understand the effects of blending high-viscosity fresh and used corn oils with diesel and jet fuel mixed with butanol and ethanol on combustion emissions such as NOX and CO. Several corn oil-based blends were formulated, characterized, and compared to understand the effect of composition on viscosity, fuel stability and energy content. The formulated corn oil blends were combusted in a 30 kW modified combustion chamber to determine the corresponding NOx and CO emission levels. Used corn oil was made and characterized by quantifying its total polar material (TPM)

"The Lythrum salicaria L. plant, from the Lythraceae family, has multiple beneficial effects on the human body, through pharmacological properties imprinted by its secondary metabolites, namely tannins. Chitosan-based biomedical materials are of increasing interest precisely due to the uniqueness of their properties, namely biocompatibility, nontoxicity, biodegradability, antimicrobial and antioxidant nature. The combination of chitosan with the plant extract aimed at obtaining new matrices, with clearly superior characteristics, compared to each material (chitosan and plant extract). This cou