Academic literature on the topic 'Stabilized micelles'

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Journal articles on the topic "Stabilized micelles"

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Wen, Shan-Ni, Chih-Hang Chu, Yu-Chao Wang, et al. "Polymer-Stabilized Micelles Reduce the Drug Rapid Clearance In Vivo." Journal of Nanomaterials 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/5818592.

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Micelles are self-assembled nanoscaled aggregates from amphiphilic unimers and can be used to encapsulate hydrophobic drugs. However, the dynamic exchanging of unimers between micelles and bulk solution often leads to micelle destabilization and subsequent leaking of the encapsulated substances. Thus, we incorporated a hydrophobic polymer into the micellar core for interlacing the unimers and stabilizing the micelle structure. The polymer-stabilized and non-polymer-stabilized micelles have similar physicochemical properties including small sizes (~35 nm), negative surface charges (~−35 mV), an
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Malkawi, Ahmad, Nasr Alrabadi, and Ross Allan Kennedy. "Dual-Acting Zeta-Potential-Changing Micelles for Optimal Mucus Diffusion and Enhanced Cellular Uptake after Oral Delivery." Pharmaceutics 13, no. 7 (2021): 974. http://dx.doi.org/10.3390/pharmaceutics13070974.

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Context: Overcoming the intestinal mucosal barrier can be a challenge in drug delivery. Nanoemulsions with negative zeta potentials can effectively permeate the mucus layer, but those with positive zeta potentials are better taken up by cells; a nanoemulsion with capricious zeta potential from negative to positive can achieve both good permeation and high uptake. Objective: This study aimed to develop dual-acting zeta-potential-amphoteric micelles enabling optimal muco-permeation and enhancement of cellular uptake. Methods: A micellar pre-concentrate was prepared from 15% Labrasol, 15% Kolliph
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Ordanini, Stefania, and Francesco Cellesi. "Complex Polymeric Architectures Self-Assembling in Unimolecular Micelles: Preparation, Characterization and Drug Nanoencapsulation." Pharmaceutics 10, no. 4 (2018): 209. http://dx.doi.org/10.3390/pharmaceutics10040209.

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Unimolecular polymeric micelles are a class of single-molecule amphiphilic core-shell polymeric architectures, where the hydrophobic core is well stabilized by the hydrophilic shell, avoiding intermolecular core-core interactions. Multi-arm copolymers with a dendritic core, as well as hyperbranched and comb-like polymers, can form unimolecular micelles easily. In this review, examples of polymers able to form detectable unimolecular micelles will be presented, summarizing the analytical techniques used to characterize the unimolecular micelles and discriminate them from other supramolecular ag
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Procházka, Karel, Kateřina Kupková, Jaroslav Burda, Zdeněk Tuzar, and Bohumil Bednář. "The photochemical stabilization of block copolymer micelles." Collection of Czechoslovak Chemical Communications 54, no. 6 (1989): 1648–60. http://dx.doi.org/10.1135/cccc19891648.

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Conditions of the polymolecular micellization of a linear three-block copolymer-polystyrene-block-polybutadiene-block-polystyrene in a binary solvent tetrahydrofuran-ethanol were determined. Photochemical stabilization of micelles by the crosslinking of polybutadiene chains in the cores induced by intense UV radiation was carried out in a tetrahydrofuran-ethanol mixture (34.5 vol. %), in which compact micelles with the polybutadiene core are formed and, at 25 °C, the micellization equilibrium is markedly shifted in favour of micelles containing a large number of associated copolymer chains. Th
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Blunden, Bianca M., Donald S. Thomas, and Martina H. Stenzel. "Analysis of Thiol-sensitive Core-cross-linked Polymeric Micelles Carrying Nucleoside Pendant Groups using 'On-line' Methods: Effect of Hydrophobicity on Cross-linking and Degradation." Australian Journal of Chemistry 64, no. 6 (2011): 766. http://dx.doi.org/10.1071/ch10448.

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Amphiphilic block copolymers were prepared via reversible–addition fragmentation chain transfer (RAFT) polymerization and their synthesis, cross-linking, and degradation were studied using on-line monitoring. The focus of this work is the systematic alteration of the hydrophobic block using copolymers based on 5′-O-methacryloyluridine (MAU) and styrene at different compositions to determine the effect of the copolymer composition on the properties of the micelle. A poly(poly(ethylene glycol) methyl ether methacrylate) (PEGMA) macroRAFT agent was chain extended with a mixture of styrene and MAU
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Gębicki, Jerzy. "Intermicellar material exchange in reverse micelles formed by ionic AOT and nonionic Igepal surfactants studied by means of pulse radiolysis. Influence of the temperature." Open Chemistry 2, no. 2 (2004): 371–87. http://dx.doi.org/10.2478/bf02475580.

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AbstractThe recombination of thiocyanate anion radicals, (SCN)2−, formed pulse radiolytically within the water pools of reverse micelles stabilized with anionic AOT and nonionic Igepal surfactants, was proved as an indicator reaction to study intermicellar exchange. It was found that the exchange process is slower inIgepal than in AOT reverse micelles with the same water to surfactant ratio. The apparent activation enthalpy and entropy of the exchange process were determined in different alkanes. For the AOT and Igepal reverse micelles the activation parameters increase with the droplet size,
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Lai, Xiang, Xuan Zhang, Shukai Li, Jie Zhang, Weifeng Lin, and Longgang Wang. "Polyethyleneimine-Oleic Acid Micelles-Stabilized Palladium Nanoparticles as Highly Efficient Catalyst to Treat Pollutants with Enhanced Performance." Polymers 13, no. 11 (2021): 1890. http://dx.doi.org/10.3390/polym13111890.

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Water soluble organic molecular pollution endangers human life and health. It becomes necessary to develop highly stable noble metal nanoparticles without aggregation in solution to improve their catalytic performance in treating pollution. Polyethyleneimine (PEI)-based stable micelles have the potential to stabilize noble metal nanoparticles due to the positive charge of PEI. In this study, we synthesized the amphiphilic PEI-oleic acid molecule by acylation reaction. Amphiphilic PEI-oleic acid assembled into stable PEI-oleic acid micelles with a hydrodynamic diameter of about 196 nm and a zet
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Gan, L. "Micellar Effects on the Formation of the 1,3,5-Trinitrobenzene-Cyanide Complex in Water." Australian Journal of Chemistry 38, no. 8 (1985): 1141. http://dx.doi.org/10.1071/ch9851141.

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The anionic σ-complex from cyanide ion and 1,3,5-trinitrobenzene in water was stabilized by cationic micelles. The binding of counter ions to the micellar head groups in hexadecyl-trimethylammonium cyanidefollowed a distribution model with the counter ion binding constant KCN = 1400 mol-1 dm3. The bromide-cyanide ion exchange constant, KCNBr, was equal to 1.28. These results rendered further support to the general applicability of the distribution model.
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Dong, He, Jessica Y. Shu, Nikhil Dube, et al. "3-Helix Micelles Stabilized by Polymer Springs." Journal of the American Chemical Society 134, no. 28 (2012): 11807–14. http://dx.doi.org/10.1021/ja3048128.

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Chen, Yongfen, and Zeev Rosenzweig. "Luminescent CdSe Quantum Dot Doped Stabilized Micelles." Nano Letters 2, no. 11 (2002): 1299–302. http://dx.doi.org/10.1021/nl025767z.

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Dissertations / Theses on the topic "Stabilized micelles"

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Arranja, Alexandra. "Development of copolymer based nanocarriers for imaging and therapy." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAE031/document.

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Le développement de nanomédicaments pour l'imagerie et le traitement du cancer a suscité un intérêt croissant à cause de leur grand potentiel. En particulier les vecteurs à base de polymères et de micelles polymères sont très intéressants, car ils peuvent être conçus avec des fonctionnalités adaptées aux besoins.Nous avons utilisé des copolymères amphiphiles triséquencés pour développer de nouveaux nanovecteurs moléculaires (unimères) et supramoléculaires (micelles stabilisées par photo- réticulation). Nous les avons fonctionnalisés avec un marqueur fluorescent ou radioactif pour permettre leu
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André, Xavier. "New double-responsive micelles of block copolymers based on N,N-Diethylacrylamide : synthesis, kinetics, micellization, and application as emulsion stabilizers." Paris 6, 2005. http://www.theses.fr/2005PA066372.

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LEGRAIN, RASPAUD SOPHIE. "Construction de transgenes specifiant la caseine kappa caprine. Etude de leur expression dans des souris transgeniques et effet de la caseine kappa recombinante sur la stabilite et la taille des micelles. Application a l'espece caprine." Paris 11, 1997. http://www.theses.fr/1997PA112184.

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Le lait des ruminants contient six lactoproteines majeures : quatre caseines (alpha-s1, alpha-s2, beta et kappa), presentes essentiellement sous forme d'agregats stables appeles micelles, et deux proteines du lactoserum (alpha-lactalbumine et beta-lactoglobuline). La caseine kappa, joue un role primordial dans la formation et la stabilite des micelles et l'obtention d'un lait riche en caseine kappa devrait permettre d'etudier ses proprietes nutritionnelles et technologiques a priori interessantes. Dans ce but, l'utilisation de la transgenese est un outil adapte et l'obtention de chevres transg
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Matondo, Hubert. "Synthese de n-4 pyridylcarbamates a activite herbicide potentielle : etude cinetique de l'influence des solutions micellaires sur leur hydrolyse." Toulouse 3, 1987. http://www.theses.fr/1987TOU30026.

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Lo, Chin-Hsuan, and 羅進軒. "Preparation of Mg Stabilized Amorphous Calcium Carbonate by Reverse Micelles." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/xhe98h.

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碩士<br>國立臺灣大學<br>化學研究所<br>107<br>Amorphous calcium carbonate (ACC) is one of the most important precursor phase of calcareous biominerals. ACC is nontoxic, biocompatible, and pH-sensitive. According to these properties, ACC has a high potential for being used as drug delivery systems. However, owing to its metastable character, it is hard to prepare nano-sized ACC in vitro. One possible solution is to dope some magnesium ions into calcium carbonate and form Mg-ACC because magnesium cations have higher dehydration energy barrier which could stabilize the ACC. To prepare Mg-ACC with the enhanced
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Jang, Ming-Shian, and 張明賢. "The Effect of Different Stabilizers on Stability, Sensitivity and Linearity of Leuco Micelle Dosimeter." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/42939363274409952446.

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碩士<br>中臺科技大學<br>醫學影像暨放射科學系暨研究所<br>101<br>This study aims to improve the stability of Leuco Micelle Dosimeter (LMD), a novel radiochromic leucodye micelle hydrogel dosimeter that is transparent and an ideal water equivalent. LMDs were stabilized separately by benzotriazole, dimethyl sulfoxide, tunsten trioxide(WO3), ascorbic acid, and tetrabromoethane. All samples were irradiated with UV and photon irradiation system using eight 8-W UV lamps (320 nm to 400 nm) with irradiation time of 0 s to 1200 s. LMD was irradiated from 0 Gy to 10 Gy using the 6-MV photon beam. The added stabilizers can slow
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Wang, Jann-Long, and 王建隆. "Static structure factor of a suspension charge-stabilized colloids:Study of the liquid-glass transition phase-diagram and micellar solution." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/60054929575319429990.

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碩士<br>國立中央大學<br>物理學系<br>86<br>Charge-stabilized colliodal dispersions are modeled by a mixture of spherical charged hard spheres which interact via Coulomb forces. The static partial structure factors S(q) of this so- called primitive model (PM) have been analytically solved by the mean spherical approximation. For point-like small ions and for weak electrostatic coupling, the PM is shown in the literature to be exactly the same as an effective one-component model (OCM). Accordingly, one ma
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André, Xavier [Verfasser]. "New double-responsive micelles of block copolymers based on N,N-diethylacrylamide : synthesis, kinetics, micellization, and application as emulsion stabilizers / vorgelegt von Xavier André." 2006. http://d-nb.info/981647200/34.

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Su, Chia-Yu, and 蘇家妤. "Targeting delivery of Lecithin-Stabilized Micellar Drug Delivery System (LsbMDDs) by Enhanced Permeability and Retention (EPR) effect and Bispecific Antibodies to Enhance Chemotherapeutic Efficacy: Physical and Biopharmaceutical Characterizations." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/u68jtf.

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Book chapters on the topic "Stabilized micelles"

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Ohya, Yuichi. "Polymeric Micelles Stabilized by Electrostatic Interactions for Drug Delivery." In ACS Symposium Series. American Chemical Society, 2013. http://dx.doi.org/10.1021/bk-2013-1135.ch007.

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Král, Petr, and Lela Vuković. "Computational Studies of Highly PEG-ylated Sterically Stabilized Micelles: Self-Assembly and Drug Solubilization." In Intracellular Delivery II. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-8896-0_16.

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Garti, Nissim, and Abraham Aserin. "Double Emulsions Stabilized by Macromolecular Surfactants." In Micelles, Microemulsions, and Monolayers. Routledge, 2018. http://dx.doi.org/10.1201/9780203747339-14.

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Koo, Otilia M., Israel Rubinstein, and Hayat Onyuksel. "Camptothecin in Sterically Stabilized Phospholipid Micelles: A Novel Nanomedicine." In Nanomedicine in Cancer. Pan Stanford, 2017. http://dx.doi.org/10.1201/b22358-14.

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"Chapter 14: Camptothecin in Sterically Stabilized Phospholipid Micelles: A Novel Nanomedicine." In Nanomedicine in Cancer, edited by Otilia M. Koo, Israel Rubinstein, and Hayat Onyuksel. CRC Press, 2017. http://dx.doi.org/10.1201/9781315114361-15.

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Mikhailovna Egorova, Elena, and Said Ibragimovich Kaba. "Some Methodological Aspects in Studies of Metal Nanoparticles’ Toxicity towards Cultured Cells." In Cytotoxicity - New Insights into Toxic Assessment. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95471.

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Some actual questions arising in studies of the toxic effects of metal nanoparticle water solutions on cultured cells are considered. First, basic conditions required for the correct determination of nanoparticle size effect; the arguments are adduced in favor of the use of number nanoparticle concentration instead of the conventional mass one. Second, the problem of invalidity of the Smoluchowski equation; for charged nanoparticles the error in zeta potential value calculated from the measured electrophoretic mobility by the Smoluchowski equation cannot be neglected. Third, for the nanoparticles stabilized with surfactants, elucidation of the mechanism of cytotoxicity should include the determination of separate contributions of surfactant molecules and micelles into the total effect on cell viability.
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"maize, 1.4-2.7%; of waxy barley, 2.1-8.3%; and of waxy swell only slightly in cold water. Granules differ in size rice 0-2.3%; thus the range of amylose contents of the and shape among plants. For example, corn starch has an waxy wheats is comparable to that of other waxy cereal average diameter of about 15 1.1,M, wheat starch has a bi-grains. Biochemical features of starch from waxy wheats modal size distribution of 25-40 and 5-10 [tm, potato are similar to those of waxy maize [71]. starch has an average size of 40 WTI, and rice starch has an Starch from barley contains 22-26% amylose, the rest average size of 5µm [99]. being amylopectin [28]. However, samples of 11-26% The particle sizes of starch granules have recently re-amylose are known, and starch from waxy barley contains ceived much attention because of their important roles in only 0-3% amylose, while high-amylose starches contain determining both the taste and mouthfeel of fat substitutes up to 45%. and the tensible properties of degradable plastic films. Amylose content of rice is categorized as very low Daniel and Whistler [39] reported that small-granule (0-9%), low (9-20%), intermediate (20-25%), or high starch about 2 !um in diameter, or similar in size to the lipid (25-33%) [124]. The amylose content of long grain rice micelle, had advantages as a fat substitute. Lim et al. [117] ranges from 23 to 26%, while medium grain ranges from investigated the use of starches of different particle size in 15 to 20% and short grain ranges from 18 to 20% [103]. degradable plastic film. They reported that a linear correla-Oat amylose content (16-27%) is similar to that of tion between film thickness and particle size and an in-wheat starch, but oat amylose is more linear and oat amy-verse linear correlation between film thickness and particle lopectin is more branched than that found in wheat [121]. size. Small-granule starches may also be used as face pow-Most sorghum starch is similar in composition to corn der or dusting powder, as a stabilizer in baking powder, and contains 70-80% branched amylopectin and 21-28% and as laundry-stiffening agents. amylose [127]. However, waxy or glutinous sorghum con-The size of the wheat starch granule is 1-30 lam, the tains starch with 100% amylopectin and has unique prop-size distribution being bimodal. Such a bimodal size distri-erties similar to waxy corn [158]. Badi et al. [11] reported bution is characteristic of wheat starch, as well as of rye 17% amylose in starch from one pearl milled population. and barley starches. Wheat starch consists of two basic Gracza [69] reviewed the minor constituents of starch. forms: small spherical granules (about 5-10 wri) and larg-Cereal starches contain low levels of lipids. Usually, the er lenticular granules (about 25-4011m). The small B-gran-lipids associated with starch are polar lipids. Generally, the ules are spherical and have a diameter of less than 10 wrt; level of lipids in cereal starch is between 0.5 and 1%. Be-a mean value of about 4 lam has been reported. The large sides low levels of other minerals, starches contain phos-A-granules are lenticular and have a diameter greater than phorus and nitrogen. In the cereals, phosphorus occurs 10 lam, with a mean 14.11.1m. In reality, the granules have a mostly in the form of phospholipids. The nitrogen is gener-continuous distribution of granule size within the range ally considered to be present as protein, but it may also be designated for that starch. Amylose and amylopectin are a constituent of the lipid fraction. intermixed and distributed evenly throughout the granule. The interaction between amylose and lipids is more Many believe that the composition and properties of small powerful by far than that between amylopectin and lipids and large granules are similar, but this is a subject of some [55]. It is well established that polar lipids (e.g., mono-argument and the subject of many research studies [42]. glycerides, fatty acids, and similar compounds) form a hel-Kulp [110] evaluated the fundamental and bread-mak-ical inclusion complex with the amylose molecule, be-ing properties of small wheat starch granules and com-tween the hydrocarbon chain of the lipid and the interior of pared them with those of regular starch. Small granules the amylose helix. were found to be lower in iodine affinity, indicating differ-ences in amylose levels or some fundamental structural differences. Gelatinization temperature ranges, water-binding capacities, and enzymic susceptibilities of small Starch is laid down in the shape of particles in special amy-granules were higher than those of regular ones. loplast cells in the plant. These particles are called gran-Rice has one of the smallest starch granules of cereal ules, and they are the means by which the plant stores en-grains, ranging in size from 3 to 5 pm in the mature grain, ergy for the carbohydrate in a space-saving way, but also to although the small granules of wheat starch are almost the make the energy easily accessible when the seed germi-same size [33]. The small granule size of that starch results nates [57]. One starch granule is synthesized in each amy-in physical properties that make it useful as a dusting flour loplast, and the shape and size of a starch granule is typical in bakeries. Rice starch amyloses have degree of polymer-of its botanical origin. ization (DP) values of 1000-1100 and average chain Starch granules are relatively dense, insoluble, and lengths of 250-320. These structural properties of amylose." In Handbook of Cereal Science and Technology, Revised and Expanded. CRC Press, 2000. http://dx.doi.org/10.1201/9781420027228-41.

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Conference papers on the topic "Stabilized micelles"

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Schabas, Greg, Matthew G. Moffitt, and David Sinton. "Microfluidic Assembly of Quantum Dot Micelles." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-42300.

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The controlled self-assembly of polymer-stabilized CdS quantum dot nanoparticles into quantum dot compound micelles (QDCMs) using microfluidics is demonstrated. In a flow-focusing configuration, water is introduced to a blend solution of block copolymer-stabilized quantum dots with amphiphilic block copolymer stabilizing chains. QDCM assembly via initial phase separation and subsequent agglomeration continue until a downstream quench step. Control over mean particle size and size distribution characteristics is demonstrated via both inlet concentrations and flow rate. The QDCMs assembled throu
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Barz, Dominik P. J., Michael J. Vogel, and Paul H. Steen. "Generation of Electrokinetic Flow in a Doped Non-Polar Liquid." In ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels collocated with 3rd Joint US-European Fluids Engineering Summer Meeting. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-30258.

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The presence of considerable amounts of free charge dispersed in a liquid is the basis for electrokinetic phenomena which are related to the existence of an electrical double layer (EDL). In polar liquids, the dissociation of electrolytes into ionic species is well understood and numerous electrokinetic phenomena are known; a good overview is given by e.g. Delgado et al. [1]. In nonpolar liquids it is known that electrical charges can exist as well. The presence of these electrical charges is utilized, for example, in colloid science to stabilize particle suspensions [2]. For this purpose, sur
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Yamamoto, Takehiro. "Numerical Analysis of Three-Dimensional Flows of Wormlike Micelles Solutions Through Abrupt Contraction Using a Modified Bautista-Manero Model." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-14008.

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Startup flows of wormlike micelles solutions in a three-dimensional rectangular abrupt contraction channel are numerically simulated using a modified Bautista-Manero model as a constitutive equation. The numerical scheme applied is based on the finite volume method with the PISO algorithm, and the DEVSS method is employed to stabilize the numerical computation. Temporal changes in micelle network structures are investigated based on the analysis of the fluidity, which represents the structural change in micelle networks. The numerical results indicate that the orientation behavior of micelle n
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Rodriguez, Victoria B., Scott M. Henry, Allan S. Hoffman, Patrick S. Stayton, Suzie H. Pun, and Xingde Li. "Stabilized Micellar Formulation of Indocyanine Green for Near-Infrared Imaging." In Biomedical Optics. OSA, 2008. http://dx.doi.org/10.1364/biomed.2008.bsua4.

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Sethuraman, Jyothi, Tara Lee Costich, Adam Carie, et al. "Abstract B22: IT-141, a stabilized polymer micelle formulation, prolongs the pharmacodynamic effect of SN-38." In Abstracts: AACR Precision Medicine Series: Cancer Cell Cycle - Tumor Progression and Therapeutic Response; February 28 - March 2, 2016; Orlando, FL. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.cellcycle16-b22.

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Carie, Adam, Taylor Buley, Bradford Sullivan, et al. "Abstract 1321: IT-147: A stabilized polymer micelle formulation of epothilone D for treatment of solid tumors." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1321.

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Sill, Kevin, Tara Lee Costich, Adam Carie, et al. "Abstract LB-190: IT-141 and IT-147, iron stabilized micellar nanoparticles for therapeutic and diagnostic applications." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-190.

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