Journal articles: 'Staging area'

1

El-Wessimy, Mahmoud, Hoda M.O. Mokhtar, and Osman Hegazy. "Enhancement Techniques for Data Warehouse Staging Area." International Journal of Data Mining & Knowledge Management Process 3, no. 6 (November 30, 2013): 1–19. http://dx.doi.org/10.5121/ijdkp.2013.3601.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Mitchell, A. P. "A VAST staging area for regulatory proteins." Proceedings of the National Academy of Sciences 105, no. 20 (May 12, 2008): 7111–12. http://dx.doi.org/10.1073/pnas.0803384105.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Temple, Claire F. L., Shirley A. Huchcroft, David J. Hurlbut, and John S. D. Davidson. "Histologic staging in malignant melanoma: Cross-sectional area revisited." Journal of Surgical Oncology 69, no. 2 (October 1998): 83–87. http://dx.doi.org/10.1002/(sici)1096-9098(199810)69:2<83::aid-jso7>3.0.co;2-e.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

LEITO, A., J. TRUU, and M. ÕUNSAAR. "The impact of agriculture on autumn staging Eurasian Cranes (Grus grus) in Estonia." Agricultural and Food Science 17, no. 1 (December 4, 2008): 53. http://dx.doi.org/10.2137/145960608784182281.

Full text

Abstract:

This paper explores the relation between the local numbers and distribution of autumn staging Eurasian Cranes (Grus grus Linn.) and agricultural land use during recent decades in Estonia. The analysis is based on the long-term monitoring data of staging cranes and the statistical data of land use in Estonia. We found that great changes in cropping area, as well as in crane numbers have taken place in Estonia since the 1960s. We also found a significant positive correlation between crane numbers and the cropping area of summer wheat, winter wheat, winter rye and all cereals together, and a negative correlation with the area of potatoes. Generally, arable land, particularly that used for growing cereals, has a great influence on the local numbers and distribution of staging cranes. Based on our findings, we predict that changes in the local numbers and distribution of Eurasian Cranes staging during their migration in Estonia and elsewhere will depend on changes in agricultural land use in staging areas, rather than on the size of the breeding population. As about 10 percent of the European Eurasian Crane population stop over in Estonia during the autumn migration, the country has an important role to play in the protection of the species.;

APA, Harvard, Vancouver, ISO, and other styles

5

Chaudhari, Mr Rohit Kiran. "Non-Linear Time History Analysis of an Elevated Water Tank." International Journal for Research in Applied Science and Engineering Technology 9, no. VI (June 30, 2021): 4327–34. http://dx.doi.org/10.22214/ijraset.2021.35939.

Full text

Abstract:

It was discovered that reinforced concrete elevated water tanks with frame staging outperformed reinforced concrete elevated water tanks with shaft staging in terms of seismic resistance. These can be due to the frame staging's seismic energy absorption capability. As a result, the primary goal of this research is to better understand the seismic behavior and performance characteristics of elevated water tanks with frame staging. Furthermore, when compared to other shapes, circular tanks have the smallest surface area for a given tank size. As a result, the amount of material needed for a circular water tank is less than for other shapes. As a result, a circular water tank was chosen, and seismic analysis of elevated RC circular water tanks was carried out according to IITK-GSDMA guidelines, with the behavior of the water tank analysed for various parameters such as zone factor, soil condition, and different staging heights. SAP 2000 was used to determine the structure's modal characteristics (mode shapes and modal participation mass ratio).

APA, Harvard, Vancouver, ISO, and other styles

6

Hipp, Jason, Jerome Cheng, Stephanie Daignault, Jefferey Sica, Michael C. Dugan, David Lucas, Yukako Yagi, Stephen Hewitt, and Ulysses J. Balis. "Automated Area Calculation of Histopathologic Features Using SIVQ." Analytical Cellular Pathology 34, no. 5 (2011): 265–75. http://dx.doi.org/10.1155/2011/606273.

Full text

Abstract:

Recently, with the advent of the 7th edition of the AJCC Cancer Staging manual, at least one set of criteria (e.g. breast) were modified to now require the measurement of maximal depth of stromal invasion. With the current manual interpretive morphological approaches typically employed by surgical pathologists to assess tumor extent, the specialty now potentially has stumbled upon a crossroads of practice, where the diagnostic criteria have exceeded the capabilities of our commonly available tools. While whole slide imaging (WSI) technology holds the potential to offer many improvements in clinical workflow over conventional slide microscopy including unambiguous utility for facilitating quantitative diagnostic tasks with one important example being the determination of both linear dimension and surface area. However, the availability of histology data in digital form is of little utility if time-consuming and cumbersome manual workflow steps are necessarily imposed upon the pathologist in order to generate such measurements, especially as encountered with the complex and ill-defined shapes inherent to infiltrative tumors. In this communication, we demonstrate the utility of the recently described SIVQ algorithm to serve as the basis of a highly accurate, precise and semi-automated tool for direct surface area measurement of tumor infiltration from WSI data sets. By anticipating the current trend in cancer staging that emphasizes increasingly precise feature characterization, as witnessed by the recent publication of AJCC's 7th edition of the Cancer Staging Manual, this tool holds promise to will be of value to pathologists for clinical utility.

APA, Harvard, Vancouver, ISO, and other styles

7

Petrie, S. A., and K. L. Wilcox. "Migration chronology of Eastern-Population Tundra Swans." Canadian Journal of Zoology 81, no. 5 (May 1, 2003): 861–70. http://dx.doi.org/10.1139/z03-063.

Full text

Abstract:

We used satellite platform transmitting transmitters (PTTs) in 19982000 to track spring and fall migratory movements of Tundra Swans (Cygnus columbianus columbianus) captured at Long Point, Ontario. Migration corridors reported here corroborated those identified in previous studies using alphanumerically coded neck collars. However, PTTs provided additional information on duration of spring and fall migrations, duration of stay in different staging regions, time spent on breeding and wintering areas, and migration speed. Birds migrated between the Atlantic coast and northern prairies along a narrow geographic corridor through portions of the southern Great Lakes. From the northern prairies, swans followed 3 corridors to breeding areas on the west coast of Hudson Bay, central High Arctic, and Mackenzie River delta. While swans spent considerable time on Great Lakes (27% of spring migration) and northern prairie (40%) staging areas in spring, the northern boreal forest was an important fall staging area (48% of fall migration). Tundra Swans spent 20% of the annual cycle on wintering areas, 28% on spring staging areas, 29% on breeding areas, and 23% on fall staging areas. The long duration of migration and the fact that birds spend half their lives on staging areas underscore the importance of conserving Tundra Swan migratory habitats. Thirty-gram neck-collar-attached PTTs were more suitable than 95-g Teflon-harness-attached backpack PTTs for tracking Tundra Swans.

APA, Harvard, Vancouver, ISO, and other styles

8

Watts, Bryan D., Fletcher M. Smith, and Barry R. Truitt. "Departure patterns of Whimbrels using a terminal spring staging area." Wader Study 124, no. 2 (August 1, 2017): 141–46. http://dx.doi.org/10.18194/ws.00075.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Smallwood, Ashley M. "Clovis Technology and Settlement in the American Southeast: Using Biface Analysis to Evaluate Dispersal Models." American Antiquity 77, no. 4 (October 2012): 689–713. http://dx.doi.org/10.7183/0002-7316.77.4.689.

Full text

Abstract:

AbstractKelly and Todd’s (1988) “high-technology forager” model predicts Clovis groups were highly mobile populations that left behind behaviorally consistent records of Clovis fluted points as evidence of their short-term occupations. Anderson’s (1990, 1996) staging-area model predicts that Clovis settlement was more gradual; groups entered the continent and slowed migration to concentrate territorial ranges around resource-rich river valleys, and these staging areas became the demographic foundations for early cultural regionalization. This study analyzes southeastern Clovis point data and biface assemblages from Carson-Conn-Short; Topper, and Williamson to test the technological implications of these two models. Significant subregional variation exists in Clovis point morphology and biface production techniques. This variation suggests the subregions represent distinct populations who distinctly altered aspects of their technology but maintained fundamental elements of the Clovis tradition. These findings are at odds with the high-technology forager model and more closely fit the staging-area model.

APA, Harvard, Vancouver, ISO, and other styles

10

Watts, Bryan D., and Barry R. Truitt. "Decline of Whimbrels within a Mid-Atlantic Staging Area (1994–2009)." Waterbirds 34, no. 3 (September 2011): 347–51. http://dx.doi.org/10.1675/063.034.0308.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Aakko, Eric, Nathan Weed, Richard Konrad, and John Wiesman. "Rethinking Volunteer Management Using a Centralized Volunteer Staging and Training Area." Disaster Medicine and Public Health Preparedness 2, no. 2 (June 2008): 127–29. http://dx.doi.org/10.1097/dmp.0b013e31816476a2.

Full text

Abstract:

ABSTRACTPublic health agencies simply do not have enough trained staff or volunteers to effectively respond to a large-scale disaster. Training volunteers “off the street” will be crucial—but time consuming—in a public health emergency. A centralized volunteer staging and training area can help to efficiently register, credential, and conduct just-in-time training of volunteers, while reducing stress, confusion, traffic congestion, and security issues at various mass dispensing clinics. (Disaster Med Public Health Preparedness. 2008;2:127–129)

APA, Harvard, Vancouver, ISO, and other styles

12

Wilson, C., P. Strimple, S. Wilson, and J. Albano. "Nontarget Deposition of Methiocarb Applied to a Foliage Plant Staging Area." Bulletin of Environmental Contamination and Toxicology 74, no. 3 (March 2005): 509–17. http://dx.doi.org/10.1007/s00128-005-0614-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Ding, Ke-Feng, Jun Li, Xiang-Xing Kong, Ke-Jun Tang, Di-Kai Bei, Ying Yuan, Su-Zhan Zhang, and Shu Zheng. "Verification of T-plus staging system for colorectal cancer based on nomogram analysis of single center’s 25-year follow-up." Journal of Clinical Oncology 34, no. 4_suppl (February 1, 2016): 516. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.516.

Full text

Abstract:

516 Background: We proposed T-plus staging system which abandon the criterion to discriminate stage II/III by lymph node status and strengthens weighting of the T stage according to cluster analysis of the summary survival data of SEER. In this study, this principle of the T-plus staging system was verified with single center data by nomogram analysis. Methods: The 1,099 patients with colorectal cancer diagnosed before 2005 were analyzed to build a novel staging system based on nomogram (nomo-staging system). The remaining 981 patients diagnosed after 2005 were used to test the performance of nomo-staging system, T-plus staging system and the 7th edition TNM staging system by Akaike information criteria (AIC), Harrell’s c-index and the area under the curve (AUC) of Receiver Operating Characteristic to predict 5-year overall survival. A smaller AIC, higher c-index and higher AUC indicated a better staging system. Results: The nomo-staging system and T-plus staging system were listed in Table 1. The validation found that the 7th edition TNM staging system showed the weakest performance. For AIC, both nomo-staging system and T-plus staging system showed smaller value than the 7th edition TNM staging system (3214.912 vs. 3224.643 vs. 3229.810). For Harrell’s c-index, both the T-plus staging system and nomo-staging system showed higher value than the 7th edition TNM staging system (0.6814 vs. 0.6787 vs. 0.6778). For AUC to predict 5-year OS, the T-plus staging system and nomo-staging system showed slightly higher value than the 7th edition TNM staging system (0.6944 vs. 0.6924 vs. 0.6913). Conclusions: We propose replacement of lymph node status as the criterion to discriminate colorectal cancer stage II/III with greater weighting of the T stage. [Table: see text]

APA, Harvard, Vancouver, ISO, and other styles

14

Carneiro, Arie, Douglas Racy, Carlos Eduardo Bacchi, Katia Ramos Moreira Leite, Renee Zon Filippi, Igor Austin Fernandes Martins, Joao Victor Salvajoli, et al. "Consensus on Screening, Diagnosis, and Staging Tools for Prostate Cancer in Developing Countries: A Report From the First Prostate Cancer Consensus Conference for Developing Countries (PCCCDC)." JCO Global Oncology, no. 7 (April 2021): 516–22. http://dx.doi.org/10.1200/go.20.00527.

Full text

Abstract:

PURPOSE To generate and present the survey results on critical issues relevant to screening, diagnosis, and staging tools for prostate cancer (PCa) focused on developing countries. METHODS A total of 36 of 300 questions concern the main areas of interest of this paper: (1) screening, (2) diagnosis, and (3) staging for various risk levels of PCa in developing countries. A panel of 99 international multidisciplinary cancer experts voted on these questions to create recommendations for screening, diagnosing, and staging tools for PCa in areas of limited resources discussed in this manuscript. RESULTS The panel voted publicly but anonymously on the predefined questions. Each question was deemed consensus if 75% or more of the full panel had selected a particular answer. These answers are based on panelist opinion not a literature review or meta-analysis. For questions that refer to an area of limited resources, the recommendations consider cost-effectiveness and the possible therapies with easier and greater access. Each question had five to seven relevant answers including two nonanswers. The results were tabulated in real time. CONCLUSION The voting results and recommendations presented in this document can be used by physicians to support the screening, diagnosis, and staging of PCa in areas of limited resources. Individual clinical decision making should be supported by available data; however, as guidelines for screening, diagnosis, and staging of PCa in developing countries have not been developed, this document will serve as a point of reference when confronted with this disease.

APA, Harvard, Vancouver, ISO, and other styles

15

Markkola, Juha, Marika Niemelä, and Seppo Rytkönen. "Diet selection of lesser white-fronted geeseAnser erythropusat a spring staging area." Ecography 26, no. 6 (December 2003): 705–14. http://dx.doi.org/10.1111/j.0906-7590.2003.03576.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Embong, R., M. H. Sanuddin, and M. S. Md Ali. "Staging of breast cancer based on the area of the primary tumour." Journal of Physics: Conference Series 1366 (November 2019): 012087. http://dx.doi.org/10.1088/1742-6596/1366/1/012087.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Smith, Ryan, Eric Ferrebee, Yanfeng Ouyang, and Jeffery Roesler. "Optimal Staging Area Locations and Material Recycling Strategies for Sustainable Highway Reconstruction." Computer-Aided Civil and Infrastructure Engineering 29, no. 8 (August 1, 2014): 559–71. http://dx.doi.org/10.1111/mice.12089.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Pfister, Charles, Brian A. Harrington, and Michael Lavine. "The impact of human disturbance on shorebirds at a migration staging area." Biological Conservation 60, no. 2 (1992): 115–26. http://dx.doi.org/10.1016/0006-3207(92)91162-l.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Chen, Lu, Wen Chen, Huan-Huan Chen, Qian Wu, Xiao-Quan Xu, Hao Hu, and Fei-Yun Wu. "Radiological Staging of Thyroid-Associated Ophthalmopathy: Comparison of T1 Mapping with Conventional MRI." International Journal of Endocrinology 2020 (October 22, 2020): 1–6. http://dx.doi.org/10.1155/2020/2575710.

Full text

Abstract:

Background. Accurate staging of patients with thyroid-associated ophthalmopathy (TAO) is crucial for clinical decision. Full cognition of pathologic changes and staging TAO using conventional T2-weighted imaging is still limited. Purpose. To investigate the feasibility of using T1 mapping to evaluate changes of extraocular muscles (EOMs) in TAO patients, as well as to compare T1 mapping and conventional T2-weighted imaging in staging TAO. Materials and Methods. Forty TAO patients were retrospectively enrolled. “Hot spot” and “cold spot” T1 relaxation times (T1RTHS and T1RTCS) of EOMs, as well as conventionally applied highest signal intensity ratio (SIR) of EOMs, were measured and compared between active and inactive groups. Results. T1RTCS and SIR were significantly higher in active TAOs than in the inactive ones ( P < 0. 001 ), while T1RTHS was not ( P = 0. 093 ). Meanwhile, T1RTCS and SIR were positively correlated with clinical activity score (r = 0.489, 0.540; P < 0. 001 ). TIRTCS and SIR showed no significant area under curve for staging TAO (0.830 vs. 0.852; P = 0. 748 ). T1RTCS ≥ 1000 alone showed optimal staging specificity (90.0%), while integration of T1RTCS ≥ 1000 and SIR ≥ 2.9 demonstrated optimal staging efficiency and sensitivity (area under curve, 0.900; sensitivity, 86.0%). Conclusions. Our findings suggest that the T1-mapping technique holds the potency to be utilized in TAO. The derived T1RTCS of EOMs, which may be associated with fat infiltration, could be a useful biomarker to stage the disease, serving added efficiency, sensitivity, and specificity to single usage of conventional SIR.

APA, Harvard, Vancouver, ISO, and other styles

20

Lightdale, Charles J., and Ketan G. Kulkarni. "Role of Endoscopic Ultrasonography in the Staging and Follow-Up of Esophageal Cancer." Journal of Clinical Oncology 23, no. 20 (July 10, 2005): 4483–89. http://dx.doi.org/10.1200/jco.2005.20.644.

Full text

Abstract:

Purpose To evaluate the role of endoscopic ultrasonography (EUS) in the initial staging and follow-up of esophageal cancer on the basis of a review of the published literature. Methods Articles published from 1985 to 2005 were searched and reviewed using the following keywords: “esophageal cancer staging,” “endoscopic ultrasound,” and “endoscopic ultrasonography.” Results For initial anatomic staging, EUS results have consistently shown more than 80% accuracy compared with surgical pathology for depth of tumor invasion (T). Accuracy increased with higher stage, and was >90% for T3 cancer. EUS results have shown accuracy in the range of 75% for initial staging of regional lymph nodes (N). EUS has been invariably more accurate than computed tomography for T and N staging. EUS is limited for staging distant metastases (M), and therefore EUS is usually performed after a body imaging modality such as computed tomography or positron emission tomography. Pathologic staging can be achieved at EUS using fine-needle aspiration (FNA) to obtain cytology from suspect Ns. FNA has had greatest efficacy in confirming celiac axis lymph node metastases with more than 90% accuracy. EUS is inaccurate for staging after radiation and chemotherapy because of inability to distinguish inflammation and fibrosis from residual cancer, but a more than 50% decrease in tumor cross-sectional area or diameter has been found to correlate with treatment response. Conclusion EUS has a central role in the initial anatomic staging of esophageal cancer because of its high accuracy in determining the extent of locoregional disease. EUS is inaccurate for staging after radiation therapy and chemotherapy, but can be useful in assessing treatment response.

APA, Harvard, Vancouver, ISO, and other styles

21

Wehrle-Haller, B., and J. A. Weston. "Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway." Development 121, no. 3 (March 1, 1995): 731–42. http://dx.doi.org/10.1242/dev.121.3.731.

Full text

Abstract:

Trunk neural crest cells segregate from the neuroepithelium and enter a ‘migration staging area’ lateral to the embryonic neural tube. After some crest cells in the migration staging area have begun to migrate on a medial pathway, a subpopulation of crest-derived cells remaining in the migration staging area expresses mRNAs for the receptor tyrosine kinase, c-kit, and tyrosinase-related protein-2, both of which are characteristic of melanocyte precursors. These putative melanocyte precursors are subsequently observed on the lateral crest migration pathway between the dermatome and overlying epithelium, and then dispersed in nascent dermal mesenchyme. Melanocyte precursors transiently require the c-kit ligand, Steel factor for survival. Although Steel factor mRNA is transiently expressed in the dorsal dermatome before the onset of trunk neural crest cell dispersal on the lateral pathway, it is no longer produced by dermatomal cells when melanocyte precursors have dispersed in the dermal mesenchyme. To assess the role of Steel factor in migration of melanocyte precursors on the lateral pathway, we analyzed melanocyte precursor dispersal and fate on the lateral pathway of two different Sl mutants, Sl, a null allele, and Sld, which lacks cell surface-associated Steel factor but produces a soluble form. No melanocyte precursors were detected in the dermatome of embryos homozygous for the Sl allele or in W mutants that lack functional c-kit. In contrast, in embryos homozygous for the Sld allele, melanocyte precursors appeared on the lateral pathway, but subsequently disappear from the dermis. These results suggest that soluble Steel factor is required for melanocyte precursor dispersal on the lateral pathway, or for their initial survival in the migration staging area. In contrast, membrane-bound Steel factor appears to promote melanocyte precursor survival in the dermis.

APA, Harvard, Vancouver, ISO, and other styles

22

Liu, Xiufeng, Nadeem Iftikhar, Huan Huo, and Per Sieverts Nielsen. "Optimizing ETL by a Two-Level Data Staging Method." International Journal of Data Warehousing and Mining 12, no. 3 (July 2016): 32–50. http://dx.doi.org/10.4018/ijdwm.2016070103.

Full text

Abstract:

In data warehousing, the data from source systems are populated into a central data warehouse (DW) through extraction, transformation and loading (ETL). The standard ETL approach usually uses sequential jobs to process the data with dependencies, such as dimension and fact data. It is a non-trivial task to process the so-called early-/late-arriving data, which arrive out of order. This paper proposes a two-level data staging area method to optimize ETL. The proposed method is an all-in-one solution that supports processing different types of data from operational systems, including early-/late-arriving data, and fast-/slowly-changing data. The introduced additional staging area decouples loading process from data extraction and transformation, which improves ETL flexibility and minimizes intervention to the data warehouse. This paper evaluates the proposed method empirically, which shows that it is more efficient and less intrusive than the standard ETL method.

APA, Harvard, Vancouver, ISO, and other styles

23

Gupta, Tina, and Vijay A. Mittal. "Advances in clinical staging, early intervention, and the prevention of psychosis." F1000Research 8 (November 29, 2019): 2027. http://dx.doi.org/10.12688/f1000research.20346.1.

Full text

Abstract:

The development of effective intervention and prevention strategies among individuals with psychosis risk syndromes may help to reduce symptomatology and conversion to a psychotic disorder. Although strides have been made in this area, more work is needed, particularly given the setbacks that remain (such as heterogeneity among this group). There has been a shift with the introduction of clinical staging models toward expanding current intervention and prevention efforts to a more developmental and transdiagnostic approach. With this, this article seeks to review treatments both recently and currently discussed in the staging literature, introduce advances in psychosis risk syndrome treatments that may be beneficial to consider in clinical staging heuristics, and pinpoint other promising options.

APA, Harvard, Vancouver, ISO, and other styles

24

Liu, Yi, Dong Zheng, Jia-jin Liu, Jian-xin Cui, Hong-qing Xi, Ke-cheng Zhang, Xiao-hui Huang, et al. "Comparing PET/MRI with PET/CT for Pretreatment Staging of Gastric Cancer." Gastroenterology Research and Practice 2019 (February 3, 2019): 1–11. http://dx.doi.org/10.1155/2019/9564627.

Full text

Abstract:

18F-FDG PET/MRI has been applied to the diagnosis and preoperative staging in various tumor types; however, reports using PET/MRI in gastric cancer are rare because of motion artifacts. We investigated the value of PET/MRI for preoperative staging compared with PET/CT in gastric cancer (GC). Thirty patients with confirmed GC underwent PET/CT and PET/MRI. TNM staging for each patient was determined from the PET/MRI and PET/CT images. The diagnostic performance of PET/MRI and PET/CT was calculated compared with the pathologic TNM stage. The two methods were compared using statistical analyses. The accuracy for T staging between PET/MRI and PET/CT was 76.9% vs. 57.7%, respectively. In T1 and T4a staging, the sensitivity and specificity for PET/MRI vs. PET/CT was 1.0 vs. 0.6 and 1.0 vs. 0.8, respectively. The area under the curve (AUC) for PET/MRI vs. PET/CT was 1.00 vs. 0.78 in the T1 stage, 0.73 vs. 0.66 in the T2 stage, 0.72 vs. 0.57 in the T3 stage, and 0.86 vs. 0.83 in the T4 stage. The accuracy for N staging of PET/MRI vs. PET/CT was 53.9% vs. 34.0%, and that for N0 vs. N+ was 85.0% vs. 77.0%. The sensitivity for PET/MRI in N3 staging was 0.67 and 0 for PET/CT. There was a statistically significant difference in the AUC for N1 staging (PET/MRI vs. PET/CT, 0.63 vs. 0.53, p=0.03). SUVmax/ADC positively correlated with tumor volume and Ki-67. PET/MRI performs more accurately in TNM staging compared with PET/CT and is optimal for accurate N staging. SUVmax/ADC has positive correlations with tumor volume and Ki-67.

APA, Harvard, Vancouver, ISO, and other styles

25

Hricak, Hedvig, Constantine Gatsonis, Dennis S. Chi, Marco A. Amendola, Kathy Brandt, Lawrence H. Schwartz, Susan Koelliker, et al. "Role of Imaging in Pretreatment Evaluation of Early Invasive Cervical Cancer: Results of the Intergroup Study American College of Radiology Imaging Network 6651–Gynecologic Oncology Group 183." Journal of Clinical Oncology 23, no. 36 (December 20, 2005): 9329–37. http://dx.doi.org/10.1200/jco.2005.02.0354.

Full text

Abstract:

Purpose To compare magnetic resonance imaging (MRI) and computed tomography (CT) with each other and to International Federation of Gynecology and Obstetrics (FIGO) clinical staging in the pretreatment evaluation of early invasive cervical cancer, using surgicopathologic findings as the reference standard. Patients and Methods This prospective multicenter clinical study was conducted by the American College of Radiology Imaging Network and the Gynecologic Oncology Group from March 2000 to November 2002; 25 United States health centers enrolled 208 consecutive patients with biopsy-confirmed cervical cancer of FIGO stage ≥ IB who were scheduled for surgery based on clinical assessment. Patients underwent FIGO clinical staging, helical CT, and MRI. Surgicopathologic findings constituted the reference standard for statistical analysis. Results Complete data were available for 172 patients; surgicopathologic findings were consistent with FIGO stages IA to IIA in 76% and stage ≥ IIB in 21%. For the detection of advanced stage (≥ IIB), sensitivity was poor for FIGO clinical staging (29%), CT (42%), and MRI (53%); specificity was 99% for FIGO clinical staging, 82% for CT, and 74% for MRI; and negative predictive value was 84% for FIGO clinical staging, 84% for CT, and 85% for MRI. MRI (area under the receiver operating characteristic curve [AUC], 0.88) was significantly better than CT (AUC, 0.73) for detecting cervical tumors (P = .014). For 85% of patients, FIGO clinical staging forms were submitted after MRI and/or CT was performed. Conclusion CT and MRI performed similarly; both had lower staging accuracy than in prior single-institution studies. Accuracy of FIGO clinical staging was higher than previously reported. The temporal data suggest that FIGO clinical staging was influenced by CT and MRI findings.

APA, Harvard, Vancouver, ISO, and other styles

26

Hochhegger, Bruno, Maria Teresa Ruiz Tsukazan, Vanessa Rezende Bortolotto, Arthur Vieira, Carlos Cezar Fritscher, Mara Lise Zanini, Eduardo Herz Berdichevski, et al. "Dual time PET-CT for mediastinal nodal staging in patients diagnosed with non-small cell lung cancer in an area with high prevalence of infectious granulomatous disease (LACOG-0114)." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e20083-e20083. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e20083.

Full text

Abstract:

e20083 Background: The role of dual-time-point PET/CT acquisition for mediastinal node staging in non-small cell lung cancer (NSCLC) is still controversial. Interpretation of PET/CT results is challenging in areas with high prevalence of infectious granulomatous diseases, whereas the use of dual-time PET/CT could reduce the false-positive results. This study aims to evaluate the performance of dual-time PET-CT for mediastinal node staging in patients with NSCLC in an area with high prevalence of infectious granulomatous diseases (i.e. 99 cases of tuberculosis per 100.000 habitants). Methods: Patients diagnosed with clinical stages I-III NSCLC performed dual-time-point PET/CT (images acquired in hour 1 and 2) followed by mediastinal lymph node biopsy. Different cut-offs for SUV were evaluated to test accuracy in each time-point. Results: One hundred patients were enrolled, of which 85 had mediastinal node biopsy after PET-CT. Median age was 65 years (range 47-80), 49 (58%) were male, 80 (94%) were current or former smokers, and 1 (1.2%) had history of tuberculosis. Dual-time-point acquisition results were similar to those in single-time-point (Table 1). The highest sensitivity (87%) and NPV (90%) was achieved when a cut-off SUV > 0 was used. Conclusions: Dual-time point PET/CT did not improve accuracy of PET/CT-based LN staging in NSCLC in an area with high prevalence of infectious granulomatous diseases. [Table: see text]

APA, Harvard, Vancouver, ISO, and other styles

27

Braak, Heiko, and Eva Braak. "Staging of Alzheimer-Related Cortical Destruction." International Psychogeriatrics 9, S1 (December 1997): 257–61. http://dx.doi.org/10.1017/s1041610297004973.

Full text

Abstract:

Currently used criteria for neuropathological diagnosis of Alzheimer's disease (AD) allow only the distinction of fully developed AD or ill-defined cases with less severe pathologic alterations. There is a need for a staging procedure that is able to supplement the currently used criteria, to allow for sufficient differentiation between the initial and intermediate stages of the illness, and to provide a characterization of the degree of involvement in the brain tissue of “nondemented, age-related controls.” The destructive process underlying AD is characterized by a typical distribution pattern of brain changes that is specific with respect to area, lamina, and even cell type. The most conspicuous change is the progressive deposition of abnormal proteins, both between and within the nerve cells. Conventional staining methods to identify these deposits lack sensitivity and specificity. Silver methods (specifically the Gallyas silver-iodide technique for neurofibrillary changes and the Campbell-Switzer silver-pyridin technique for brain amyloid) are by far the best suited to diagnostic work. They are inexpensive, simple to use, and far more reliable. This article describes the patterns of staining typically found with each of these techniques in the brains of patients with progressively severe AD and describes how the specific changes observed can be used as a staging system for diagnostic purposes.

APA, Harvard, Vancouver, ISO, and other styles

28

Echeverría, Sandra E., Luisa N. Borrell, Diane Brown, and George Rhoads. "A Local Area Analysis of Racial, Ethnic, and Neighborhood Disparities in Breast Cancer Staging." Cancer Epidemiology Biomarkers & Prevention 18, no. 11 (October 20, 2009): 3024–29. http://dx.doi.org/10.1158/1055-9965.epi-09-0390.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Connolly, James L. "Changes and Problematic Areas in Interpretation of the AJCC Cancer Staging Manual, 6th Edition, for Breast Cancer." Archives of Pathology & Laboratory Medicine 130, no. 3 (March 1, 2006): 287–91. http://dx.doi.org/10.5858/2006-130-287-capaii.

Full text

Abstract:

Abstract Context.—Tumor stage is an important prognostic factor and guides therapy for patients with breast cancer. The American Joint Committee on Cancer (AJCC) periodically updates the staging standards. This article describes changes and problematic areas in interpretation of the AJCC Cancer Staging Manual, 6th edition, for breast cancer and provides practical advice. Objectives.—This article reviews the variety of practical problems that can arise during assessment of the pathologic stage and other prognostic/predictive factors included in the College of American Pathologists Checklist for Evaluation of Resected Breast Cancers. Potential practical difficulties that can arise include the classification of lymph nodes, for example, isolated tumor cells, micrometastases, metastases, and the combination of locations. Another difficult area is assignment of a correct size. The use of clinical and imaging studies for optimal pathologic staging is discussed. Finally, the proper use of the TNM descriptors is described. Conclusions.—The various practical problems that can arise during the assessment of important prognostic and predictive features included in the College of American Pathologists Checklist for Evaluation of Resected Breast Cancers are discussed, and specific recommendations are given.

APA, Harvard, Vancouver, ISO, and other styles

30

Li, Yanxia, Earle Holmes, Karan Shah, Kevin Albuquerque, Anna Szpaderska, and Çağatay Erşahin. "The Prognostic Value of Lymph Node Cross-Sectional Cancer Area in Node-Positive Breast Cancer: A Comparison with N Stage and Lymph Node Ratio." Pathology Research International 2012 (October 4, 2012): 1–8. http://dx.doi.org/10.1155/2012/161964.

Full text

Abstract:

The number of positive axillary lymph nodes (LNs) is the only node-related factor for prognostic evaluation of breast cancer recognized by AJCC (TNM staging). However, N staging may not completely reflect LN tumor involvement due to the erroneous count of LNs in the presence of matted LNs and different tumor volume in LNs. Additionally, the positive/total LN ratio (LNR) has been shown to outperform N staging in survival prediction. In our study, to better quantify the tumor involvement of axillary LNs, we measured the cross-sectional cancer area (CSCA) of the positive LNs in 292 breast cancer patients diagnosed between 1998 and 2000 in our institution and compared its prognostic value to that of number of positive LNs (metLN)/N stage and LNR. Statistical analyses of these three LN-related factors were performed by Kaplan-Meier method and multivariate Cox's regression model. Patients were divided into three groups based on the different LN CSCA (<50, 50–500, and >500 mm2), or LNR (<0.1, 0.1–0.65, and >0.65), or N stage (N1–N3). Multivariate analysis demonstrated LNR was the most significant LN-related survival predictor with hazard ratio (HR) 25.0 (), compared to the metLN (HR 0.09, ) and CSCA (HR 2.24, ).

APA, Harvard, Vancouver, ISO, and other styles

31

Nilsson, Leif. "Field choice of autumn staging and wintering geese in southwestern Sweden 1977/1978–2011/2012." Ornis Svecica 23, no. 1 (January 1, 2013): 3–45. http://dx.doi.org/10.34080/os.v23.22581.

Full text

Abstract:

Goose counts have been made in September, October, November and January since September 1977. Staging Greylag Geese Anser anser increased from 19,000 in 1984 to 250,000 in 2008–2010, mainly due to a corresponding population growth, and a wintering tradition was established with a maximum of 50,000 in 2008. Staging and wintering White-fronted Geese Anser albifrons increased from less than 3,000 to up to 40,000 and 25,000, respectively, due to a northward shift of the sites. Wintering Canada Geese Branta canadensis increased from less than 10,000 to a peak of 70,000 in 2009–2010, mainly an effect of the growing Swedish population. Staging of the Barnacle Goose Branta leucopsis is a new tradition established in autumn 2,000, with no less than 150,000 in 2011. Sweden is the autumn staging area for almost the entire Taiga Bean Goose Anser fabalis fabalis population that has decreased in recent years. During the same period Tundra Bean Geese A. f. rossicus have started to stage in larger numbers, the overall counts of Bean Geese giving an impression of stability in recent years.

APA, Harvard, Vancouver, ISO, and other styles

32

Green, Martin, and Leif Nilsson. "The importance of offshore areas in southern Öresund, Sweden, for staging and wintering sea ducks." Ornis Svecica 25, no. 1–2 (April 1, 2015): 24–39. http://dx.doi.org/10.34080/os.v25.21853.

Full text

Abstract:

The occurrence of wintering and spring-staging sea ducks in the southern part of Swedish Öresund was surveyed from air and ship during the period 2001–2011. Altogether 22 air and 20 boat surveys were made during the months November–May and here we present the results regarding five commonly recorded sea ducks. We present the numbers recorded and the general time pattern of occurrence during winter and spring in the area. Recorded numbers are then used for evaluating the importance of the area, both in relation to national wintering totals as well as to international (Baltic) totals. Southern Swedish Öresund is of no larger importance for Long-tailed Duck Clangula hyemalis in winter and spring. The area is however of national importance for both Velvet Scoter Melanitta fusca and Common Scoter Melanitta nigra in winter. Peak numbers of Common Scoters do also reach international importance. Southern Swedish Öresund is of large national and international importance for both wintering and spring-staging Eider Somateria mollissima and Red-breasted Merganser Mergus merganser.

APA, Harvard, Vancouver, ISO, and other styles

33

Cunningham, James R., Cheryl Dodd, Jon Rittenbach, and Mitch Clemens. "Final report from a registry study of patients with active cancer undergoing ecological staging." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e22501-e22501. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e22501.

Full text

Abstract:

e22501 Background: The host-cancer relationship can be viewed as a set of tumor supportive and inhibitory interactions, that is as an ecosystem. An advantage of such a perspective might include a more dynamic understanding of the selection pressures affecting tumor evolution. If so then a means of detecting and measuring those forces would be of help in understanding that drive and point to potential therapeutic clinical interventions. Towards this goal a registry study of patients with invasive cancer was conducted to examine readily available clinical measures to inform an ecological staging system. Methods: Eligibility for registry participation included age of 18 years or older, active cancer requiring treatment, life expectancy estimated to be at least six months and willingness to provide informed consent for this IRB-approved study. Ecological staging was then conducted at entry assessing 22 separate clinical parameters from history, physical exam and laboratory known to effect tumor biology, grouped into eight profiles and scored using a trichotomization of data, increasing score corresponding to an increase in positive tumor selection. To aggregate data from the profiles, a geometric figure, an octamer, or ecogram, was constructed, vertices representing the net score of each of the eight profiles. We hypothesize that the area bounded by the polygon, ecogram area (EA) would reflect an index of adverse, tumor-supporting ecological influence. Overall survival was determined from time of diagnosis of cancer until time of registry closure. Results: 15 subjects, eight female, seven male, ages 53-84 (median 64) participated in the registry. Complete ecological staging was obtained from all participating subjects, an indication of feasibility for collection of such data in the clinic. Resulting EA ranged 12-fold (0-12.1) across subjects suggesting sensitivity of EA to differences in selection pressures among the participants; ecogram morphology from individual subjects demonstrated unique shapes, an indication of specificity for character of individual tumor ecological landscape. Mean overall survival for participants from time of cancer diagnosis was 265 weeks. For 12 subjects with advanced stage disease, overall survival was inversely related to ecogram area (r = -.45). Conclusions: Ecological staging of cancer from clinical parameters proved feasible in this registry study of patients with active cancer. Ecological information from those parameters when aggregated using a geometric figure, an ecogram, demonstrated both sensitivity and specificity for differences among participants. For those subjects with advanced stage disease, ecogram area was inversely related to overall cancer survival. Ecological staging may be a useful tool in gauging selection pressures affecting cancer evolutionary tendency and of potential benefit to oncologists in forecasting such development.

APA, Harvard, Vancouver, ISO, and other styles

34

Su, Ting-Shi, Shi-Xiong Liang, Li-Qing Li, Qiu-Hua Liu, Xiao-Fei Zhu, and Ping Liang. "A new staging system for radiotherapy-based treatment of hepatocellular carcinoma: A multicenter cohort study." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e16155-e16155. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16155.

Full text

Abstract:

e16155 Background: External beam radiation therapy has been used as a palliative to radical treatment of hepatocellular carcinoma (HCC) depending on different tumor status, liver function and patient's general state of health. The existing models of HCC staging cannot perfectly predict the prognosis of radiotherapy. In this study, we aimed to set up a new staging system for radiotherapy-based treatment by incorporating bilirubin-albumin (ALBI) grade and tumor status for the prognostic classifications of HCC. Methods: This multicenter cohort study included 878 HCC patients who received radiotherapy-based treatment. A new staging system was established: stage I, solitary nodule without macrovascular invasion or 2-3 nodules with no more than 3.0 cm each other and PS 0-2 (Ia: ALBI-1 grade; Ib: ALBI-2 or 3 grade); stage II: 2-3 nodules with anyone more than 3.0 cm or ≥4 nodules and PS 0-2 (IIa: ALBI-1 grade; IIb: ALBI-2 grade); stage III: macrovascular invasion or regional lymph node metastasis or distant metastasis and PS 0-2 (IIIa: ALBI-1 grade; IIIb:ALBI-2 grade); stage IV: ALBI-3 grade without stage I patient or/and PS score 3-4. The new modified staging system and the existing staging systems, such as the BCLC, TNM, CNLC staging systems were used for prognostic analysis. All patients were separated into different stages and substages. The long-term overall survival outcomes and time-dependent receiver operating characteristic (ROC) were analyzed. Results: A training cohort of 595 patients underwent stereotactic body radiotherapy (SBRT) from 2011 to 2017 and an external validation cohort of 283 patients underwent intensity-modulated radiotherapy (IMRT) from 2000 to 2013 were included into establishing and validating the new staging system. In the training cohort, the median follow-up time was 55 months (range, 6–100 months), and the new staging system had a good discriminatory ability to separate patients into different stages with 4 notably different curves and substages with 7 notably different curves. BCLC staging could not differentiate stage 0 to A, and stage C to D in these selected patients. TNM staging could not completely distinguish stage IIIb to IV, but also stage Ia to Ib. CNLC staging could not differentiate among stage IIIa, IIIb, and IV. In the external validation, the median follow-up time was 95 months (range, 9–120 months), and the new staging system also had a good discriminatory ability to separate patients into different stages with 4 notably different curves and substages with 7 notably different curves. The new staging system had a better area under curve of time-dependent ROC than BCLC, TNM and CNLC staging in both SBRT and IMRT cohorts. Conclusions: The new modified (Su’s) staging system could provide a good discriminatory ability to separate patients into different stages and substages after radiotherapy treatment. It may be used to supplement the other HCC staging systems.

APA, Harvard, Vancouver, ISO, and other styles

35

Oganesyan, R. S., and N. S. Grachev. "SURGICAL TREATMENT OF LYMPHATIC MALFORMATIONS OF THE HEAD AND NECK AREA IN CHILDREN." Pediatria. Journal named after G.N. Speransky 100, no. 3 (May 28, 2021): 141–46. http://dx.doi.org/10.24110/0031-403x-2021-100-3-141-146.

Full text

Abstract:

The variety of forms and localizations of lymphatic malformations (LMs) in the head and neck region determine the lack of unified approach to the treatment of this pathology. The surgical approach is divided into minimally invasive sclerotherapy technique, used mainly for macrocystic forms of LM, and classical surgery, which includes a wide range of surgical interventions on organs and structures of the head and neck. A combination of these two methods and planning of surgical staging are the key to success in the treatment of mixed forms of LMs and malformations of complex localizations with extensive distribution.

APA, Harvard, Vancouver, ISO, and other styles

36

Özkan, Meryem Ö., Mine Şencan Eren, Sibel Göksel, Yakup Yürekli, and Sabri Barutça. "One patient with two different 18-fluorodeoxyglucose positron emission tomography/computed tomography views." International Journal of Diagnostic Imaging 1, no. 2 (June 26, 2014): 114. http://dx.doi.org/10.5430/ijdi.v1n2p114.

Full text

Abstract:

A normoglycemic patient with a diagnosis of laryngeal cancer underwent F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (F-18 FDG PET/CT) for staging purposes and two different results were obtained. In the first assessment, F-18 FDG uptake of the primary lesion was very low, but a significant F-18 FDG uptake was noted in the second evaluation. F-18 FDG PET/CT is used for the diagnosis, staging and re-staging, as well as for the assessment of response to treatment in oncological patients. F-18 FDG uptake is associated with fasting blood glucose levels and satiety. The lower and upper limit of fasting blood glucose is variable between centers. In this present case report, we want to discuss the factors responsible for not detecting F-18 FDG uptake in the area of primary lesion in a normoglycemic patient with laryngeal cancer.

APA, Harvard, Vancouver, ISO, and other styles

37

Cunningham, James R., Jon Rittenbach, Mitch Clemens, Cheryl Dodd, Ashley Wilson, and Kaikuihala Roberson. "Measuring parameters of the cancer ecosystem for cancer ecological staging." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e14684-e14684. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14684.

Full text

Abstract:

e14684 Background: Cancer progression through clonal evolution and emergent phenotypic heterogeneity is thought to reflect stochastic events such as genetic drift. This divergence over time in the character of a neoplasm might also reflect genetic selection, analogous to other populations in nature, to maximize niche resource utilization. We hypothesized that selection pressures operate in patients with cancer to drive cancer evolution, are clinically identifiable, their influence measurable. Methods: To develop a system for cancer ecology staging, a feasibility study recruited 15 patients with active cancer from any site, with expected survival of more than 6 months and providing informed consent. A set of clinical parameters obtained from a patient questionnaire, physical exam and laboratory testing was used to generate eight separate ecological profiles of tumor microenvironment, chronic inflammation, energy balance, psychosocial stress, GI microbiome, endocrine environment, skeletal remodeling and environmental mutagenesis. A scoring system, based on evidence of positive selection was designed to quantitate the individual profiles. Profile scores were then aggregated using a 2-D radar plot to generate a polygon, an ‘ecogram’, whose area, it is hypothesized, corresponds to the net level of selection pressure influencing tumor evolution. Results: Ecological profiles were obtained from each of 15 patients allowing determination of the ecogram area (EA) bounded by the polygon. EA determinations ranged widely among the 15 patient, from 0-12.7 arbitrary units (au, mean 5.01± 0.80). Ecograms from individual patients demonstrated unique shapes suggesting specificity for individual patient ecology. EA measurements were then used to inform an ecological staging system based on a simplified dichotomization, low/high, of ecosystem resources and threats. Of 15 patients, 6 were considered to have high resources (EA > 5au) available to support tumor evolution. High anti-tumor threat, measured by CD3 lymphocyte immunohistochemical scoring, was detected in 11 patients. Conclusions: An ecological assessment of patients with active cancer appears feasible. Inter-patient variation in ecogram area and morphology suggests there are potential important differences in genetic selection found between patients and should be correlated with survival outcomes in future studies, validation offering a target for ecosystem ‘restoration’.

APA, Harvard, Vancouver, ISO, and other styles

38

STENHOUSE, IAIN J., CARSTEN EGEVANG, and RICHARD A. PHILLIPS. "Trans-equatorial migration, staging sites and wintering area of Sabine’s GullsLarus sabiniin the Atlantic Ocean." Ibis 154, no. 1 (October 31, 2011): 42–51. http://dx.doi.org/10.1111/j.1474-919x.2011.01180.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Choi, Sunkyung, and Shinya Hanaoka. "Diagramming development for a base camp and staging area in a humanitarian logistics base airport." Journal of Humanitarian Logistics and Supply Chain Management 7, no. 2 (August 7, 2017): 152–71. http://dx.doi.org/10.1108/jhlscm-12-2016-0044.

Full text

Abstract:

Purpose The purpose of this paper is to develop a method for diagramming a base camp or space for emergency workers and a staging area to be used during sorting, storing, loading, and unloading of relief goods in a humanitarian logistics base airport. Design/methodology/approach A method is developed based on a synthesis of the relevant literature and current practices of airports. This provides a means for estimating the area required for each facility and visualizes the layout of the base through an adjacency diagram and a bubble diagram. The method is applied to the Shizuoka Airport in Japan as a case study. Findings The proposed method can be used to determine the approximate size and layout of a humanitarian logistics base in an airport based on the affected population and the number of emergency workers. Research limitations/implications Airport operation regulations and mathematical models from architectural planning need to be reflected further. Practical implications The method provides potential operational improvements for policies and standards for airport operations and enables government officials and humanitarian logistics organizations to identify concerns in facilitating and managing constraints in existing airports. Originality/value This study addresses the detailed phases in a diagramming for a humanitarian logistics base airport by integrating an architectural approach and airport disaster management. The results highlight the importance of managing the flexible use of space to improve effective humanitarian logistics.

APA, Harvard, Vancouver, ISO, and other styles

40

Oppel, Steffen, D. Lynne Dickson, and Abby N. Powell. "International importance of the eastern Chukchi Sea as a staging area for migrating king eiders." Polar Biology 32, no. 5 (February 4, 2009): 775–83. http://dx.doi.org/10.1007/s00300-008-0580-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Kang, Ha Yan, Hyun Deok Shin, Suk Bae Kim, and Il Han Song. "Prognosis predictability of hepatocellular carcinoma according to staging systems in hepatitis B virus-endemic area." Clinics and Research in Hepatology and Gastroenterology 36, no. 4 (August 2012): 357–64. http://dx.doi.org/10.1016/j.clinre.2011.12.018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Ou, X., X. Zhou, X. He, H. Ying, and C. Hu. "Validation of the 8th Edition of AJCC/UICC Staging System for Nasopharyngeal Carcinoma in the Non-Endemic Area and Proposing a New N-Staging System." International Journal of Radiation Oncology*Biology*Physics 105, no. 1 (September 2019): E394—E395. http://dx.doi.org/10.1016/j.ijrobp.2019.06.1570.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

YANG, HONG-YAN, BING CHEN, MARK BARTER, THEUNIS PIERSMA, CHUN-FA ZHOU, FENG-SHAN LI, and ZHENG-WANG ZHANG. "Impacts of tidal land reclamation in Bohai Bay, China: ongoing losses of critical Yellow Sea waterbird staging and wintering sites." Bird Conservation International 21, no. 3 (May 18, 2011): 241–59. http://dx.doi.org/10.1017/s0959270911000086.

Full text

Abstract:

SummaryThe coast of Bohai Bay, north-western Yellow Sea, is critical for waterbirds migrating along the East Asia-Australasian Flyway. Between 1994 and 2010, a total of 450 km2of offshore area, including 218 km2of intertidal flats (one third of the original tidal area in the bay), has been reclaimed along the bay for two industrial projects. This has caused the northward migrants to become concentrated in an ever smaller remaining area, our core study site. The spring peak numbers of two Red Knot subspecies in the East Asia-Australasian Flyway,Calidris canutus piersmaiandC. c. rogersi, in this so far little affected area increased from 13% in 2007 to 62% in 2010 of the global populations; the spring peak numbers of Curlew SandpiperC. ferrugineaincreased from 3% in 2007 to 23% in 2010 of the flyway population. The decline in the extent of intertidal mudflats also affected Relict GullsLarus relictus, listed by IUCN as ‘Vulnerable’; during normal winters 56% of the global population moved from the wintering habitats that were removed in Tianjin to the relatively intact areas around Tangshan. Densities of wintering Eurasian CurlewNumenius arquata, and spring-staging Broad-billed SandpiperLimicola falcinellusand SanderlingCalidris albahave also increased in the remaining areas. With the proposed continuation of land reclamation in Bohai Bay, we predict waterbird densities in the remaining areas to increase to a point of collapse. To evaluate the future of these fragile, shared international resources, it is vital to promote an immediate conservation action plan for the remaining coastal wetlands in this region, and continued population monitoring to determine the effects of this action.

APA, Harvard, Vancouver, ISO, and other styles

44

Okazumi, Shinichi, Hideaki Shimada, and Hisahiro Matsubara. "PS02.072: ESTIMATION OF DOWN STAGING AFTER CHEMORADIOTHERAPY FOR T4 ESOPHAGEAL CANCER BY QUALITATIVE RESPONSE EVALUATION USING RENDERED MD-CT AND THE OUTCOME OF CURATIVE RESECTION." Diseases of the Esophagus 31, Supplement_1 (September 1, 2018): 140–41. http://dx.doi.org/10.1093/dote/doy089.ps02.072.

Full text

Abstract:

Abstract Background A new qualitative diagnostic image which represented the histological responses was developed using 3D-volume rendered MD-CT, and which was applied for the estimation of down staging after chemoradiotherapy (CRT) followed curative resection for T4 advanced esophageal cancer. Methods 95 cases of T4 advanced esophageal cancer which underwent CRT were enrolled CRT protocol: 40–60Gy dose of irradiation were done and concurrently CDDP 15(mg/mm2) and 5-FU 500(mg/mm2) were administered in day 1–5 i.v.. Down staging estimation by MD-CT rendering: Contrast media (300mg iodine/ml, 3ml/kg) was administrated intravenously (3ml/sec). CT (GE: Light Speed 16) scans were performed (slice thickness: 1.3 mm) at 50 seconds delay before and after CRT. A workstation Virtual Place(AZE) was used for rendering the diagnostic image which represented histological response with specially selected colors and opacities. Down staging was diagnosed by the fibrotic change(CT value < 50HU) of the cancer tissue in the border area to the adjacent organs. The first estimation were done at 40Gy and the down staging cases were examined for resection and no down staging cases were continued to 60Gy. Results Down staging ratio were 48% in T4 aorta, 17% in trachea,35.7% in bronchus, and 44.4% in pulmonary vein. In the irradiation dose of 41.3 ± 2.5Gy, 24cases (25.3%) (Group A) and in 61.8 ± 3.15Gy,12 cases (12.6%) obtained down staging. 30 days after CRT, 13 cases of Group A and 10 of Group B underwent curative esophagectomy. In the pathological examination, response rate were 60.8% in group A and 80% in group B. The outcome after resection was 40% in the five year survival (n = 23). Conclusion The qualitative diagnostic image rendered by 3D-enhanced MD-CT was useful for the down staging evaluation after CRT to estimate curability of followed resection for T4 advanced esophageal cancer. Early estimation of the down staging at the dose of 40Gy seemed to be necessary to plan the followed resection safely and survival benefit were obtained in the curatively resected case with histological response. Disclosure All authors have declared no conflicts of interest.

APA, Harvard, Vancouver, ISO, and other styles

45

Lin, Yao Lin, Wei Yang, and Ming Sheng Liu. "Central Plant Control Optimization with a Thermal Chilled Water Energy Storage System: A Case Study in a High-Tech Building." Advanced Materials Research 1070-1072 (December 2014): 1989–93. http://dx.doi.org/10.4028/www.scientific.net/amr.1070-1072.1989.

Full text

Abstract:

The paper presents the study on the control optimization of the central cooling plant system including thermal chilled water energy storage (TES) tank in a high-tech building consists of office area, clean room and lab space. The optimized control sequences were implemented on the cooling tower staging, cooling tower fan/condenser water pump/primary chilled water pump staging and speed control, chiller staging, TES pump speed and TES modulation valves control, and secondary chilled water loop differential pressure control. The proposed control effectively resolved the problem of fluctuation in the secondary chilled water supply temperature during charging cycle and temperature increase during the discharging cycle. The number of primary chilled water pumps, condenser water pumps and cooling tower fans were also reduced to minimum after the optimization. Implementation of optimized control sequences is predicted to have an annual electricity savings of 856,125 kWh, which is about 20% of the total central plant energy consumption.

APA, Harvard, Vancouver, ISO, and other styles

46

Renzulli, Matteo, Alfredo Clemente, Daniele Spinelli, Anna Maria Ierardi, Giovanni Marasco, Davide Farina, Stefano Brocchi, et al. "Gastric Cancer Staging: Is It Time for Magnetic Resonance Imaging?" Cancers 12, no. 6 (May 29, 2020): 1402. http://dx.doi.org/10.3390/cancers12061402.

Full text

Abstract:

Gastric cancer (GC) is a common cancer worldwide. Its incidence and mortality vary depending on geographic area, with the highest rates in Asian countries, particularly in China, Japan, and South Korea. Accurate imaging staging has become crucial for the application of various treatment strategies, especially for curative treatments in early stages. Unfortunately, most GCs are still diagnosed at an advanced stage, with the peritoneum (61–80%), distant lymph nodes (44–50%), and liver (26–38%) as the most common metastatic locations. Metastatic disease is limited to the peritoneum in 58% of cases; in nonperitoneal distant metastases, the most involved GC metastasization site is the liver (82%). The eighth edition of the tumor-node-metastasis staging system is the most commonly used system for determining GC prognosis. Endoscopic ultrasonography, computed tomography, and 18-fluorideoxyglucose positron emission tomography are historically the most accurate imaging techniques for GC staging. However, studies have recently shown renewed interest in magnetic resonance imaging (MRI) as a useful tool in GC staging, especially for distant metastasis assessment. The technical improvement of diffusion-weighted imaging and the increasing use of hepatobiliary contrast agents have been shown to increase the diagnostic performance of MRI, particularly for detecting peritoneal and liver metastasis. However, no principal oncological guidelines have included the use of MRI as a first-line technique for distant metastasis evaluation during the GC staging process, such as the National Comprehensive Cancer Network Guidelines. This review analyzed the role of the principal imaging techniques in GC diagnosis and staging, focusing on the potential role of MRI, especially for assessing peritoneal and liver metastases.

APA, Harvard, Vancouver, ISO, and other styles

47

Yu, Tingting, Jin Geng, Wei Song, and Zhonghua Jiang. "Diagnostic Accuracy of Magnifying Endoscopy with Narrow Band Imaging and Its Diagnostic Value for Invasion Depth Staging in Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis." BioMed Research International 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/8591387.

Full text

Abstract:

Background and Goals.This study aimed to investigate the diagnostic accuracy of magnifying endoscopy with narrow band imaging (ME-NBI) and determine its value for invasion depth staging in esophageal squamous cell carcinoma.Methods. We searched the PubMed, Embase, and Cochrane Library databases and found relevant studies published up to December 2016. Quality Assessment of Diagnostic Accuracy Studies 2 was used to evaluate the quality of the studies. We calculated sensitivity, specificity, and positive and negative likelihood values from forest plots and determined summary receiver operating characteristic (sROC) curves for ME-NBI diagnostic accuracy analysis.Results. Ten studies met our criteria and were selected for this meta-analysis. A total of 1,033 patients underwent ME-NBI, and 207 of these patients received a diagnosis of staging mucosal or submucosal invasion. The pooled sensitivity, specificity, and positive and negative likelihood values of ME-NBI for the diagnostic rate were 0.90 (95% CI, 0.71–0.97), 0.90 (95% CI, 0.80–0.95), 6.74 (95% CI, 3.52–712.89), and 0.20 (95% CI, 0.10–0.42), respectively. The area under the curve (AUC) was 0.95 for all studies.Conclusions. ME-NBI provides a high diagnostic rate in evaluating the esophagus to diagnose squamous cell carcinoma. In the differentiation for invasion depth staging, ME-NBI was demonstrated to be superior to white light endoscopy and had a similar diagnostic rate compared with HF-EUS. However, HF-EUS had high positive likelihood values for invasion depth staging, suggesting that HF-EUS is a reliable method for confirming invasion depth staging.

APA, Harvard, Vancouver, ISO, and other styles

48

Lisovsky, Mikhail, Shannon N. Schutz, Michael G. Drage, Xiaoying Liu, Arief A. Suriawinata, and Amitabh Srivastava. "Number of Lymph Nodes in Primary Nodal Basin and a “Second Look” Protocol as Quality Indicators for Optimal Nodal Staging of Colon Cancer." Archives of Pathology & Laboratory Medicine 141, no. 1 (September 28, 2016): 125–30. http://dx.doi.org/10.5858/arpa.2015-0401-oa.

Full text

Abstract:

Context.—Evaluation of 12 or more lymph nodes (LNs) is currently used as a quality indicator for adequacy of pathologic examination of colon cancer resections. Objective.—To evaluate the utility of a focused LN search in the immediate vicinity of the tumor and a “second look” protocol in improving LN staging in colon cancer. Design.—Lymph nodes were submitted separately from the primary nodal basin (PNB) and secondary nodal basin (SNB) defined as an area less than 5 cm away and an area greater than 5 cm away from the tumor edge, respectively, in 201 consecutive resections (2010–2013). One hundred sixty-eight consecutive tumors (2006–2009) were used as a control group. A second search was performed in all cases that were N0 after the first search. Results.—In cases that were N0 after the first search, 20.9 ± 10.8 LNs were collected from the PNB, compared to 8.5 ± 9.1 from the SNB. Positive LNs were found in N+ tumors in the PNB in all cases but in only 9% (4 of 46) of SNBs (P < .001). A second search increased node count by an average of 10 additional LNs. In 5 of 114 cases (4.4%), N0 after the first search converted to N+ after a second search that yielded 1 to 4 positive LNs, all of which were in the PNB. Conclusions.—Emphasis on the number of LNs examined from the PNB and a “second look” protocol improve nodal staging.

APA, Harvard, Vancouver, ISO, and other styles

49

Lewis, Benjamin S., Michael W. Eichholz, Tina Yerkes, and John M. Coluccy. "Food Resources for Wintering and Spring Staging American Black Ducks." Journal of Fish and Wildlife Management 10, no. 2 (September 1, 2019): 492–99. http://dx.doi.org/10.3996/102018-jfwm-096.

Full text

Abstract:

Abstract Habitat restoration and enhancement objectives for wintering waterfowl are typically derived by a bioenergetics modeling approach. This approach has been developed as a planning tool to identify the amount of foraging habitat required to meet North American Waterfowl Management Plan population objectives. Our objective was to provide the energetic supply component of the bioenergetics model at an important wintering area for American black ducks Anas rubripes in the Atlantic Flyway, the Eastern Shore of Virginia. We estimated food availability among four main wetland cover types used by overwintering American black ducks: brackish water, freshwater, mudflat, and salt marsh. Mudflat (221 ± 50 kg/ha) and salt marsh (728 ± 175 kg/ha) had the highest amounts of available invertebrate food density, and freshwater (42 ± 9 kg/ha) had the highest amounts of available seed biomass. Our results suggest that seed density found in freshwater wetlands on the Eastern Shore of Virginia is considerably lower than densities found in inland freshwater cover types used by dabbling ducks. We also found that levels of invertebrate density found in Virginia mudflat and salt marsh are considerably lower than levels on Long Island, New York, and in southern New Jersey. Lower levels of food density compared with both more inland and northern wintering areas suggest that American black ducks wintering in Virginia are more likely to be limited by forage availability than American black ducks and other dabbling ducks wintering both inland and in the northern portion of the wintering range.

APA, Harvard, Vancouver, ISO, and other styles

50

Hartmann, Jessica A., Barnaby Nelson, Aswin Ratheesh, Devi Treen, and Patrick D. McGorry. "At-risk studies and clinical antecedents of psychosis, bipolar disorder and depression: a scoping review in the context of clinical staging." Psychological Medicine 49, no. 2 (June 4, 2018): 177–89. http://dx.doi.org/10.1017/s0033291718001435.

Full text

Abstract:

AbstractIdentifying young people at risk of developing serious mental illness and identifying predictors of onset of illness has been a focus of psychiatric prediction research, particularly in the field of psychosis. Work in this area has facilitated the adoption of the clinical staging model of early clinical phenotypes, ranging from at-risk mental states to chronic and severe mental illness. It has been a topic of debate if these staging models should be conceptualised as disorder-specific or transdiagnostic. In order to inform this debate and facilitate cross-diagnostic discourse, the present scoping review provides a broad overview of the body of literature of (a) longitudinal at-risk approaches and (b) identified antecedents of (homotypic) illness progression across three major mental disorders [psychosis, bipolar disorder (BD) and depression], and places these in the context of clinical staging. Stage 0 at-risk conceptualisations (i.e. familial high-risk approaches) were identified in all three disorders. However, formalised stage 1b conceptualisations (i.e. ultra-high-risk approaches) were only present in psychosis and marginally in BD. The presence of non-specific and overlapping antecedents in the three disorders may support a general staging model, at least in the early stages of severe psychotic or mood disorders.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Staging area'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles