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1

Alffenaar, J. W. C., S. L. Stocker, L. Davies Forsman, et al. "Clinical standards for the dosing and management of TB drugs." International Journal of Tuberculosis and Lung Disease 26, no. 6 (2022): 483–99. http://dx.doi.org/10.5588/ijtld.22.0188.

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BACKGROUND: Optimal drug dosing is important to ensure adequate response to treatment, prevent development of drug resistance and reduce drug toxicity. The aim of these clinical standards is to provide guidance on ‘best practice´ for dosing and management of TB drugs.METHODS: A panel of 57 global experts in the fields of microbiology, pharmacology and TB care were identified; 51 participated in a Delphi process. A 5-point Likert scale was used to score draft standards. The final document represents the broad consensus and was approved by all participants.RESULTS: Six clinical standards were de
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Tasrim, Indriani, Silviana Hasanuddin, La Ode Muh Fitrawan, and La Ode Muhammad Adlu. "Evaluasi Manajemen Logistik Obat di Instalasi Farmasi Dinas Kesehatan Kota Kendari Tahun 2021." Jurnal Pharmacia Mandala Waluya 3, no. 2 (2024): 115–31. http://dx.doi.org/10.54883/jpmw.v3i2.101.

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Drug logistics management is a series of activities involving aspects of planning, procurement, storage, distribution and elimination of drugs as well as recording and reporting of drugs that are managed optimally to achieve the accuracy of the total of drugs, types of drugs and health supplies. This study aimed to evaluate the drug logistics management at the Pharmacy Installation in Health Office of Kendary City in 2021. The type of study was a descriptive-evaluative research . The population amounted to 4 informants , and the data was collected through observation and interviews. The qualit
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3

Grady, Lee T. "Challenges in Drug Standard Setting." American Journal of Pharmaceutical Education 52, no. 4 (1988): 379. http://dx.doi.org/10.1016/s0002-9459(24)02941-3.

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4

Syahyeri, Afrizal. "The Evaluation Of Drug Storage at The Pharmacy Warehouse Gamping 1 Health Center, Sleman Regency." Journal of health research and technology 3, no. 2 (2025): 130–44. https://doi.org/10.58439/jhrt.v3i2.276.

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Introduction: Pharmaceutical services at community health center include 2 (two) activities include the management of pharmaceutical preparations and consumable medical materials and clinical pharmacy service activities. One of the pharmaceutical preparation management activities is drug storage. Drug storage is one way to guarantee the quality of drugs so that they are safe. Objective: To evaluate the drug storage at the Gamping 1 Health Center, Sleman Regency. Methods: This research design is a descriptive non-experimental study using a cross sectional approach. Using a checklist sheet guide
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Akkerman, O. W., R. Duarte, S. Tiberi, et al. "Clinical standards for drug-susceptible pulmonary TB." International Journal of Tuberculosis and Lung Disease 26, no. 7 (2022): 592–604. http://dx.doi.org/10.5588/ijtld.22.0228.

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BACKGROUND: The aim of these clinical standards is to provide guidance on ‘best practice´ for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB).METHODS: A panel of 54 global experts in the field of TB care, public health, microbiology, and pharmacology were identified; 46 participated in a Delphi process. A 5-point Likert scale was used to score draft standards. The final document represents the broad consensus and was approved by all 46 participants.RESULTS: Seven clinical standards were defined: Standard 1, all patients (adult or child) who have symptoms and signs co
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Buchtova, Tereza, David Lukac, Zdenek Skrott, Katarina Chroma, Jiri Bartek, and Martin Mistrik. "Drug–Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics." International Journal of Molecular Sciences 24, no. 3 (2023): 2885. http://dx.doi.org/10.3390/ijms24032885.

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Cannabidiol (CBD) is an easily accessible and affordable Marijuana (Cannabis sativa L.) plant derivative with an extensive history of medical use spanning thousands of years. Interest in the therapeutic potential of CBD has increased in recent years, including its anti-tumour properties in various cancer models. In addition to the direct anticancer effects of CBD, preclinical research on numerous cannabinoids, including CBD, has highlighted their potential use in: (i) attenuating chemotherapy-induced adverse effects and (ii) enhancing the efficacy of some anticancer drugs. Therefore, CBD is ga
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R, Thirumalaisamy. "Comparative Anti–Alzheimer’s Potential Evaluation of Curcumin and Curcumin Analogues obtained from ZINC Database: An in-Silico Validation." TEXILA INTERNATIONAL JOURNAL OF PUBLIC HEALTH 9, no. 4 (2021): 269–83. http://dx.doi.org/10.21522/tijph.2013.09.04.art023.

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Curcumin and its eleven analogues obtained from the ZINC database were screened for its anti-Alzheimer’s potential validated through in silico approach. Curcumin, eleven curcumin analogues from the ZINC database, and six standard anti-Alzheimer’s drugs were obtained from SWISS ADME and Pub chem database. All obtained molecules were subjected to drug-likeness, molecular docking, and ADMET analysis. Curcumin and eleven curcumin analogues show no violations against five drug-likeness rules, whereas 2 standard drugs (CID¬_11269353, CID_46883536) out of 5 screened standard drug molecules shows viol
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Arias, Jalayne J. "Becoming the Standard: How Innovative Procedures Benefitting Public Health are Incorporated into the Standard of Care." Journal of Law, Medicine & Ethics 39, S1 (2011): 102–5. http://dx.doi.org/10.1111/j.1748-720x.2011.00578.x.

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Physicians’ resistance to implementing innovative medical procedures due to a perceived risk of liability can adversely affect the public’s health. This resistance prevents public access to procedures that could better treat communicable or chronic diseases. Innovative procedures, for the purpose of this article, are medical practices that require physicians to modify current clinical approaches to treating or diagnosing a patient’s condition and incorporate: (1) newly developed tests, treatments, drugs or devices (e.g., genetic screening to identify drug sensitivities to reduce adverse drug r
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9

Bandarapalle, Kishore, Rajasekhar K. K, K. Ramesh Reddy, et al. "A review on CDSCO: central drug standard control organization and regulation on medical devices." Future Journal of Pharmaceuticals and Health Sciences 5, no. 2 (2025): 174–80. https://doi.org/10.26452/fjphs.v5i2.754.

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India has served as a central location for overseeing numerous multi-center trials. This evolution may have its roots in the Central Drug Standard Control Organization (CDSCO), which is led by the Drug Controller General of India (DCGI). It oversees the standards for managing clinical trials in India, including trial conduct, Indian regulations, and the quality of data generated. It is imperative that all clinical trials currently carried out in India adhere to the recently updated Schedule Y of the Drugs and Cosmetics Act and the International Conference on Harmonization's Good Clinical Pract
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10

Aghniya Choirunnisa, Risma Pertiwi, Zahra Septina, and Acim Heri Iswanto. "Penerapan Lean Six Sigma Dalam Waktu Tunggu Pelayanan Resep Di Rumah Sakit : Studi Literatur." Jurnal Ilmu Kedokteran dan Kesehatan Indonesia 3, no. 2 (2023): 203–11. http://dx.doi.org/10.55606/jikki.v3i2.1730.

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Long waiting time is one component that has the potential to cause patient dissatisfaction. If the waiting time is long, it will reduce patient comfort and affect patient utility in the future. The method used in this research is Literature Review, namely by collecting and processing research data that has existed before with the 2018-2022 range. The results of this study found that there was a waiting time for drugs, both concoctions and standard drugs, that were not in accordance with the minimum service standards, so that waste was found. There are various types of waste that are found resu
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11

Chiang, S. S., S. M. Graham, H. S. Schaaf, et al. "Clinical standards for drug-susceptible TB in children and adolescents." International Journal of Tuberculosis and Lung Disease 27, no. 8 (2023): 584–98. http://dx.doi.org/10.5588/ijtld.23.0085.

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BACKGROUND: These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.METHODS: Fifty-two global experts in paediatric TB participated in a Delphi consensus process. After eight rounds of revisions, 51/52 (98%) participants endorsed the final document.RESULTS: Eight standards were identified: Standard 1, Age and developmental stage are critical considerations in the assessment and management of TB; Standard 2, Children and adolescents with symptoms and signs of TB disease should undergo prompt evaluation, and dia
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Zaafira, Reyhan Diva, and Yardi Yardi. "Analysis of the Effectiveness of Drug Management Systems in Tangerang Selatan General Hospital in 2021." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 10, no. 1 (2024): 62–72. http://dx.doi.org/10.22487/j24428744.2024.v10.i1.16479.

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Background: Pharmaceutical services are closely related to an optimal drug management system, where with optimal drug management, drug availability can be guaranteed, and patient demand can be fulfilled. Objectives: This study aimed to analized the effectiveness of the drug management system at the distribution stage at the Tangerang Selatan General Hospital in 2021. Material and Methods: The method used wasbased on a book by Satibi in the form of percentage of compatibility of drugs with drug stock cards, Turn Over Ratio (TOR), drug availability levels, percentage of expired and damaged drugs
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13

Aisyah, Noor, Rizkiyah Rizkiyah, Fitrah Shafran Ilahi, and Ayu Soraya. "PROFIL PENGELOLAAN OBAT DI RUMAH SAKIT DAERAH IDAMAN BANJARBARU." Jurnal Insan Farmasi Indonesia 5, no. 2 (2022): 249–57. http://dx.doi.org/10.36387/jifi.v5i2.1253.

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Effective drug management is carried out to prevent drug shortages, drug excess which causes the drug to reach the expiration date. The purpose of this study was to determine the percentage of drug planning accuracy, the frequency of drug procurement, the percentage of damaged and expired drugs, and the percentage of dead stock of drugs at Idaman Hospital Banjarbaru. This research was conducted with a descriptive, non-experimental observational design. The data taken is retrospective data, then analyzed quantitatively and the data is presented descriptively. The results of this study show that
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14

Antara, I. Kadek Bayu, I. Nyoman Gede Sugiartha, and Desak Gde Dwi Arini. "Tanggung Jawab Pelaku Usaha terhadap Harga Eceran Obat yang Dijual Kepada Konsumen Melebihi Harga Standar." Jurnal Preferensi Hukum 3, no. 1 (2022): 54–59. http://dx.doi.org/10.22225/jph.3.1.4624.54-59.

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Setting a standard retail price on drug packaging is something that must be done for every drug maker, if the product packaging does not state the standard retail price or when buying and selling takes place does not heed the contents of the relevant law, the government will carry out guidance and supervision of drug maker or seller. The purposes of this study are to reveal the protection of drug consumers who consume drugs whose prices exceed the standard retail price and the responsibility of business actors to the retail prices of drugs sold to consumers that exceed the standard price. This
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15

Cai, Meng, Fabin Han, Nanxiang Xiong, et al. "Standards of induced pluripotent stem cells derived clinical-grade neural stem cells preparation and quality control (2021 China version)." Journal of Neurorestoratology 9, no. 1 (2021): 13–30. http://dx.doi.org/10.26599/jnr.2021.9040005.

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Induced pluripotent stem cells (iPSCs) have become the leading research object in the clinical application of restorative medicine. They are easily generated from diverse cell sources and functionally indistinguishable from embryonic stem cells without the accompanying ethical issues. To date, the use of iPSC-derived neural stem cells and their progeny in the treatment of neurodegenerative and injurious diseases has achieved good results, with great potential in cell drug development. However, because of some unique biological properties and differences from traditional drug production process
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Al Yaqut, Muhammad Arto, Satibi Satibi, and Iswandi Iswandi. "Analysis of Drug Management at Tegal City Pharmaceutical Installation." JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) 14, no. 2 (2024): 101. http://dx.doi.org/10.22146/jmpf.88053.

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Background: Medicine is one of the most essential elements in health service efforts. Good drug management will affect the availability of drugs and improve the degree of health in the community.Objectives: This study aims to determine the effectiveness and efficiency of drug management at the Tegal City Pharmaceutical Installation in 2021 related to compliance with the Indonesian Ministry of Health and WHO indicators.Methods: This research is descriptive research with a quantitative approach. Data was taken retrospectively through document tracing and supplemented with qualitative data throug
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17

Kouimtsidis, Christos, Jo Edwards, Christine Wallis, and Karen Drabble. "Drug Interventions Programme: clinical profile of service users v. attendees of standard services." Psychiatric Bulletin 32, no. 7 (2008): 245–47. http://dx.doi.org/10.1192/pb.bp.107.017301.

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Aims and MethodWe conducted a retrospective survey of all cases referred to the Drug Interventions Programme in Hertfordshire for the first 9 months in order to compare them with those referred to one of the community drug and alcohol teams.ResultsThe Drugs Interventions Programme had significantly more White British clients and clients who had dropped out from previous treatment. Compared with community team clients, the Programme had a higher percentage of clients with an opioid problem (92%), of whom a high percentage also misused other substances (78%) and injected drugs (30%, half of whom
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18

M, Mauliana, Wiryanto W, and Urip Harahap. "Evaluation of Drug Management Achievement in Pharmacy Installation of Langsa General Hospital." Asian Journal of Pharmaceutical Research and Development 8, no. 1 (2020): 5–10. http://dx.doi.org/10.22270/ajprd.v8i1.648.

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Objective: to evaluate the achievements of drug management in Pharmacy Installation of Langsa General Hospital
 Design: The study used descriptive designs for 2018 data which were retrospective and prospective. Data was collected in the form of quantitative and qualitative data from document observations and interviews with relevant Pharmacy Installation officers.
 Interventions: the intervened variable were drug selection, planning and procurement, and distribution.
 Main outcome measures: the main measurement in this study were suitability of drug items available with the Nati
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19

Philippidis, Alex. "Alpine's Gold Standard Approach to Drug Development." GEN Edge 2, no. 1 (2020): 180–88. http://dx.doi.org/10.1089/genedge.2.1.33.

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20

Luber, Andrew D., and Concepta Merry. "Standard methods to measure HIV drug concentrations." Lancet 358, no. 9285 (2001): 930. http://dx.doi.org/10.1016/s0140-6736(01)06066-4.

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21

Sabarudin, Sabarudin, Sunandar Ihsan, Fifi Nirmala, and Rifa’atul Mahmudah. "Drug Management Quality During the Covid-19 Pandemic at Inpatient Health Centers in Kendari City." MEDULA 9, no. 2 (2022): 114. http://dx.doi.org/10.46496/medula.v9i2.25466.

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Background: WHO has declared Covid-19 a global pandemic after the infection case reached more than 121,000 cases. Puskesmas is the primary service closest to the community, so it has a significant role in dealing with COVID-19. The quality of health services at Puskesmas was influenced by drug management. On the other hand, the COVID-19 pandemic has resulted in changes in health services at Puskesmas. Hence, it is necessary to evaluate the quality of drug management at Puskesmas during the Covid-19 pandemic. Aims: This study aimed to evaluate the quality of drug management during the COVID-19
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Singh, Priya. "Agranulocytosis - A Rare Side Effect of Standard Dose Ceftriaxone Therapy." Journal of Advanced Research in Medicine 09, no. 1 (2022): 24–26. http://dx.doi.org/10.24321/2349.7181.202205.

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In the current era of medical science, agranulocytosis is rarely found. Chemotherapeutic agents and various non-chemotherapeutic drugs commonly cause agranulocytosis. Agranulocytosis can occur any time during the therapy in hospital, and patients may remain symptomless. So, we should do regular cell count to reach the diagnosis in such cases. An appropriate antibiotic or drug-change, investigations to rule out sepsis and granulocyte colony-stimulating factor (G-CSF) injection can be given as the management part. The patient should be monitored daily and observed till the normalization of neutr
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Sadgunottama goud kamparaj, Kudagi B L, Karikal H P, Muthiah N S, and Pravin Kumar R. "Evaluation of the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 3391–95. http://dx.doi.org/10.26452/ijrps.v11i3.2476.

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The present study is objected to evaluate the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy. Conventional anti-epileptic rodent models like Maximal Electric Shock (MES)- induced convulsions and Pentylenetetrazol (PTZ) induced convulsions were used. The animals were randomly divided into six groups, with six rats in every group. Here anti-epileptic activity of cilostazol with two different doses (10 mg/kg i.p and 20 mg/kg i.p) was compared with standard drug and standard drug + Cilostazol two different doses (10 mg/kg i.p and 20 mg/kg
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International, Journal of Medical Science and Advanced Clinical Research (IJMACR). "Drug utilization study in department of obstetrics and gynecology at a tertiary care teaching hospital." International Journal of Medical Science and Advanced Clinical Research (IJMACR) 8, no. 2 (2025): 08–13. https://doi.org/10.5281/zenodo.15239753.

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<strong>Abstract</strong> <strong>Objective: </strong>To evaluate the trend of medication prescriptions in the department of obstetrics and gynaecology at a tertiary care teaching hospital. <strong>Methods</strong>: A prospective observational study on drug utilization patterns was done in the department of obstetrics and gynaecology at a tertiary care teaching hospital for 18 months. All inpatients and outpatients were included. After gaining informed consent, patients who met the inclusion criteria were enrolled. Medication orders were observed for prescription patterns. WHO Prescription ind
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Soedarsono, Soedarsono, and Agustinus Rizki Wirawan Riadi. "Tuberculosis Drug-Induced Liver Injury." Jurnal Respirasi 6, no. 2 (2020): 49. http://dx.doi.org/10.20473/jr.v6-i.2.2020.49-54.

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Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO). The standard therapy consists of 5 first-line anti-TB drugs (isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin). TB drugs have mild to severe side effects. Side effects that arise not only cause mortality and morbidity but also cause the cessation of treatment with the effect of not achieving cure, even arising drug resistance. Drug-induced liver injury (DILI) is a f
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Alfulaila, Alfulaila, Ika Purwidyaningrum, and Samuel Budi Harsono. "Evaluation of drug inventory management in Anwar Medika Hospital Sidoarjo." International journal of health sciences 7, S1 (2023): 2954–65. http://dx.doi.org/10.53730/ijhs.v7ns1.14617.

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Drug management is carried out effectively and efficiently to prevent drug shortages, drug prescription outside the formulary. Drug management at Anwar Medika Hospital Pharmacy Installation has not been carried out according to standards. This study aims to evaluate the management of drug management at the Pharmacy Installation of Anwar Medika Hospital and to make recommendations regarding the problems that occur. This research is a descriptive verification study with qualitative and quantitative data. The samples used were primary and secondary data from selection, planning, procurement, rece
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Rumagit, Hanna M., Friska M. Montolalu, and Mitra W. Timburas. "Analysis of Medicine Management in the Pharmacy Installation at Hospital X of Tomohon City." Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) 7, no. 2 (2024): 41–51. https://doi.org/10.55724/jbiofartrop.v7i2.479.

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This study aims to analyze the efficiency of medicine management at Hospital X in Tomohon City by evaluating such indicators as selection, procurement, distribution, and use of drugs. It employed a descriptive method to examine retrospective data gleaned from interviews to assess the compliance of medicine management with the standards set by the Indonesian Ministry of Health, WHO, and Regulations of the Ministry of Health. The results indicated that the selection phase only reached 55.65% compliance with the National Formula, while procurement showed a budget allocation of 25.08%, which was b
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Sinkova, M. N., L. K. Isakov, E. Yu Plotnikova, and O. L. Barbarash. "Role of physical training in cardiac rehabilitation in patients with congestive heart failure and type 2 diabetes mellitus." Meditsinskiy sovet = Medical Council, no. 16 (October 30, 2024): 101–7. http://dx.doi.org/10.21518/ms2024-391.

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Introduction. Currently, the effectiveness of cardiac rehabilitation of patients with comorbid CHF using physical training when prescribing optimal drug therapy, including SGLT2 drugs, has not been studied.Aims. To study the effect of controlled physical training on the quality of life and prognosis of patients with CHF comorbid with type 2 diabetes mellitus against the background of rational pharmacotherapy.Materials and methods. The study included 74 patients with CHF against the background of type 2 diabetes mellitus, receiving optimal drug therapy, with mandatory intake of SGLT2 drugs. Two
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Rokayah, Hanni Prihhastuti Puspitasari, and Yunita Nita. "Evaluation of rational drug use in primary healthcare centres of Probolinggo District, Indonesia." Pharmacy Education 24, no. 3 (2024): 401–5. http://dx.doi.org/10.46542/pe.2024.243.401405.

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Background: The Indonesian government has been working on optimising drug use in primary healthcare centres (puskesmas) of the Probolinggo District Health Office (dinkes). Objective: This study aimed to evaluate the rationality of drug use (RDU) using indicators set by the Indonesian Ministry of Health. Method: A retrospective descriptive study was conducted using data from 33 Puskesmas in Probolinggo Dinkes during the year 2022. Data on patients diagnosed with Acute Respiratory Infection (ARI) non-pneumonia (n = 36,378), non-specific diarrhoea (n = 4,291), and myalgia injection cases (n = 9,6
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Shreedevi, Huddar, Anup Kumar Elleri, and Devaraj C. "EVALUATION OF VEDANASTHAPANA (ANALGESIC) EFFECT OF MOCARASA: SHALMALI NIRYASA (SALMALIA MALABARICA – GUM DC)." International Journal of Research in Ayurveda and Pharmacy 15, no. 1 (2024): 40–45. http://dx.doi.org/10.7897/2277-4343.15110.

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Pain, said to be one of nature’s earliest signs of morbidity and is also one of the most typical presentations seen in medical practice, brings disturbance in the equilibrium state of a person. In order to manage such conditions, several drugs are available in the present era. Among them, some are expensive, and some have side effects such as dyspepsia and gastrointestinal bleeding, burning sensations, etc. For relieving pain, Acharya Charaka mentioned Vedanasthapana Daseimani Gana (Group of 10 Drugs), of which Mocarasa (Salmalia malabarica Dc.) is one among them. This study is taken up to eva
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Sabarudin, Ihsan Sunandar, Nirmala G. Fifi, and Mahmudah Rifa'atul. "Quality of Drug Management during the Covid-19 Pandemic at Outpatient Health Center, Kendari City." International Journal of Current Science Research and Review 05, no. 10 (2022): 3805–11. https://doi.org/10.5281/zenodo.7132489.

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<strong>ABSTRACT: </strong>Covid-19, declared a global pandemic by WHO, has infected 10,242,298 cases in Indonesia. Especially in Southeast Sulawesi, there were 521 cases, with the most in Kendari city. Public health centers are generally the first goal of treatment by the community, so they must be able to manage and utilize their resources effectively and efficiently in breaking the chain of Covid-19 transmission. COVID-19 impacts changes in health services carried out at the Puskesmas, so it is crucial to evaluate the quality of drug management at the puskesmas during the Covid-19 pandemic.
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George, Deepthi Mary, Krishnadas M. S., Thennavan A., Anjaly M. V., and Princy Louis Palatty. "Comparing the antiepileptic effects of atorvastatin, celecoxib, ashwagandha, clove oil, and Sodium valproate on chemo-shock induced seizures in male Wistar albino rats." International Journal of Basic & Clinical Pharmacology 12, no. 2 (2023): 186–91. http://dx.doi.org/10.18203/2319-2003.ijbcp20230384.

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Background: Antiepileptic potential of statins, COX inhibitors and other herbal medications are to be evaluated in experimental animals so that the most efficacious can be translated for human use as an adjunct to the commonly used anti-epileptic drugs. Methods: This experimental animal study grouped 30 male Wistar albino rats into 6 groups with each containing 5 rats of which one group was control, one was the standard drug and the other 4 were treatment groups which received Atorvastatin, Celecoxib, Ashwagandha and Clove oil. These drugs were administered 30 minutes prior to administering Pe
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Yuliana, Depi, Faizul Bayani, Dedent Eka Bimmaharyanto, et al. "Evaluasi Waktu Tunggu Pelayanan Resep Obat Racikan dan Non Racikan pada Pasien Rawat Jalan di Apotek." Bioscientist : Jurnal Ilmiah Biologi 9, no. 2 (2021): 659. http://dx.doi.org/10.33394/bioscientist.v9i2.4950.

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The quality of health services is still not optimal, especially in terms of patient dissatisfaction with drug services at pharmacies. A more efficient system can be built only if the waiting time evaluation has been carried out at pharmacies that provide drug prescriptions for patients. This study aims to evaluate the waiting time for prescription services at pharmacies to achieve patient satisfaction with drug services at pharmacies. In this study, Angkasa Farma's pharmacy became the subject of evaluation. The study was conducted with an observational design using descriptive analysis. The wa
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Chotimah, Dian Indah Nurul, Anindi Lupita Nasyanka, and Janatun Na’imah. "Compliance Level of High Alert Drug Labelling with Standard Operating Procedures of Pharmacy Installation of Emergency Department at Hospital X Gresik." PHARMADEMICA : Jurnal Kefarmasian dan Gizi 2, no. 1 (2022): 42–47. http://dx.doi.org/10.54445/pharmademica.v2i1.28.

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High Alert drugs are drugs that must be watched out for causing unwanted effects if an error occurs in drug administration. In addition, it can also cause complications and side effects from the drug itself which can endanger patient safety. This study aims to determine the compliance level of high alert drug labelling. It used observational research with descriptive data analysis. The population was high alert drug storage of Pharmacy Installation of Emergency Department at Hospital X Gresik and the sample was labelling of all high alert drugs of Pharmacy Installation of Emergency Department
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Hastings, K. L. "Assessment of immunosuppressant drug carcinogenicity: standard and alternative animal models." Human & Experimental Toxicology 19, no. 4 (2000): 261–65. http://dx.doi.org/10.1191/096032700678815837.

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Drugs intended for use in preventing allograft rejection in transplant patients are likely to be administered chroni-cally; thus, it is normally expected that sponsors would conduct nonclinical studies to determine the carcinogenic potential of candidate compounds. For pharmaceuticals other than biologic agents, this would mean that rodent carcinogenicity bioassays would be performed under most circumstances. Immunosuppressant drugs have presented unique challenges with respect to the issue of carcino-genicity bioassays. The pharmacological activity of ther-apeutic immunosuppressants is though
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Kumar, Devender, Shivali Rahi, and Arpana Rana. "Comparative study of updated Clinical Trial Regulations in India with respect to Australia, Europe, Japan and US." International Journal of Drug Regulatory Affairs 9, no. 1 (2021): 48–61. http://dx.doi.org/10.22270/ijdra.v9i1.455.

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The national regulatory authorities, such as the US Food and Drug Administration (FDA), the European Medicines Agency (EMA), Central Drugs Standard Control Organization and the Australian Therapeutic Goods Administration (TGA), approve every drug that is prescribed for patients around the world. The process of approval undertaken by pharmaceutical companies for drug candidates consists of a series of phases to ensure the product is safe and effective at treating the disease.&#x0D; In this paper, we will compare the clinical trial regulations of India with respect to Australia, Europe, Japan &a
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37

Farrell, Ann T., and Richard Pazdur. "Oncology Drug Review Process." Journal of the National Comprehensive Cancer Network 1, no. 1 (2003): 109–13. http://dx.doi.org/10.6004/jnccn.2003.0011.

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The U.S. Food and Drug Administration facilitates the development of drugs intended to treat cancer and other serious or life-threatening diseases. This article describes the new drug application (NDA) process, endpoints used in oncologic trials, and recent initiatives to expedite the review of drugs used to treat serious and life-threatening diseases. The Food and Drug Administration can grant either regular or accelerated marketing approval for oncology drugs. Regular approval is based on endpoints demonstrating that the drug provides a clinical benefit, such as longer life, enhanced quality
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38

Bhattacharya, Niharika Sahoo. "Recent developments in herbal drug standard in India." International Journal of Complementary and Alternative Medicine 12, no. 5 (2019): 186–88. http://dx.doi.org/10.15406/ijcam.2019.12.00471.

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39

McLeod, Donald C., and William J. Taylor. "Therapeutic Drug Monitoring as a Standard of Care." Drug Intelligence & Clinical Pharmacy 19, no. 6 (1985): 473–74. http://dx.doi.org/10.1177/106002808501900611.

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40

ZOLER, MITCHEL L. "Drug-Eluting Stents Meet Standard of Cost Effectiveness." Internal Medicine News 38, no. 6 (2005): 58. http://dx.doi.org/10.1016/s1097-8690(05)70199-2.

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41

Carrera, Pricivel M. "A Standard For Affordable And Sustainable Drug Prices." Health Affairs 38, no. 7 (2019): 1229. http://dx.doi.org/10.1377/hlthaff.2019.00520.

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42

Huynh, Karina. "Drug-coated balloon superior to standard balloon angioplasty." Nature Reviews Cardiology 14, no. 7 (2017): 383. http://dx.doi.org/10.1038/nrcardio.2017.77.

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Espinal, Marcos A., Sang Jae Kim, Pedro G. Suarez, et al. "Standard Short-Course Chemotherapy for Drug-Resistant Tuberculosis." JAMA 283, no. 19 (2000): 2537. http://dx.doi.org/10.1001/jama.283.19.2537.

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44

Bai, Yoon Kyeong, and Mi-Young You. "New Drug Listing Process and Reimbursement Standard Management." Journal of Digestive Cancer Research 11, no. 2 (2023): 104–7. http://dx.doi.org/10.52927/jdcr.2023.11.2.104.

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45

Faisal, Mohammed, Bairy Sridhar, and KN Sunil Kumar. "Analytical standards for root and leaf of Ishwari- Aristolochia indica Linn." Journal of Scientific and Innovative Research 4, no. 2 (2015): 94–99. http://dx.doi.org/10.31254/jsir.2015.4209.

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Analytical standard is a numerical value or specific property that quantifies the purity and quality of drug and formulated medicine. By standardizing raw drugs, methods, and formulations we can provide standard parameters to assess the quality, safety and efficacy of medicines. Such evaluation of a crude drug is necessary for assessing phytochemical variations, deterioration, substitution, and adulteration. Ayurvedic drug Ishwari’s botanical source is Aristolochia indica Linn. The synonym Nakuli has been used instead of Ishwari in Samhithas. The drug has been mentioned in different form for t
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46

Huddar, Shreedevi, Elleri Anup Kumar, and Murunni Rekha. "In Vivo Evaluation of Sothaghna Karma (Anti-Inflammatory Activity) of Bilwa (Aegle marmelos Corr.) Moola Twak and Patra - A Comparative Study." Journal of Ayurveda and Integrated Medical Sciences 8, no. 10 (2023): 61–68. http://dx.doi.org/10.21760/jaims.8.10.9.

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One of the characteristics of living tissues is its ability to react to injury, there occurs Inflammation. Inflammation is identified as a symptom according to modern science, whereas in Ayurveda, it is correlated to Sotha, considered as a separate clinical condition, mentioning its Lakshana’s (Signs &amp; Symptoms) and Upadrava (Complications) in relation with several ailments. Since ancient times, human societies have searched several Sotha Hara Dravyas. In the literature of Ayurveda, Bilwa (Aegle marmelos Corr.) is mentioned as one of the Shwayathuhara / Sotha Hara Dravyas among Charaka Das
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Fatin, Mia N. A., ED Y. M. Pasha, Khairunnisa Fadhilah, and Vera L. Fitriani. "EVALUASI POLA PERESEPAN PADA PASIEN LANJUT USIA MENGGUNAKAN WHO PRESCRIBING INDICATORS." Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 7, no. 1 (2022): 84–91. http://dx.doi.org/10.36387/jiis.v7i1.827.

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Older patients are very susceptible to drug use problems. Drug use problems are related to physiological conditions that affect the pharmacokinetics and pharmacodynamics of the drug. This study aimed to evaluate drug prescribing pattern in older patients at Pasundan Health Center Bandung. Data were retrospectively collected from prescriptions from March to June 2021. The pattern of prescribing drugs was evaluate using the WHO prescribing indicator with five indicators: the number of drugs per prescription, antibiotic use, generic drugs, the percentage of injection preparations, essential drug
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De Groote, Mary A., Janet C. Gilliland, Colby L. Wells, et al. "Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs againstMycobacterium tuberculosis." Antimicrobial Agents and Chemotherapy 55, no. 3 (2010): 1237–47. http://dx.doi.org/10.1128/aac.00595-10.

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ABSTRACTMethodologies for preclinical animal model testing of drugs againstMycobacterium tuberculosisvary from laboratory to laboratory; however, it is unknown if these variations result in different outcomes. Thus, a series of head-to-head comparisons of drug regimens in three commonly used mouse models (intravenous, a low-dose aerosol, and a high-dose aerosol infection model) and in two strains of mice are reported here. Treatment with standard tuberculosis (TB) drugs resulted in similar efficacies in two mouse species after a low-dose aerosol infection. When comparing the three different in
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K., RAVISHANKAR, GNANESWARI K., and THIRUMALA DEVI S. "Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula." GSC Advanced Research and Reviews 18, no. 2 (2024): 160–66. https://doi.org/10.5281/zenodo.11216232.

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Analgesic and Anti-inflammatory activities of ethanolic fruit extract of&nbsp;<em>Terminalia chebula&nbsp;</em>was evaluated using tail-flick method, eddy&rsquo;s hot plate method, acetic acid induced writhing responses and&nbsp;<em>in-vivo</em>&nbsp;anti-inflammatory property was determined using carrageenan rat paw edema. The ethanolic fruit extract of&nbsp;<em>Terminalia chebula&nbsp;</em>at different concentrations significantly inhibited the nociception in comparision with different standard drugs that showed anti-nociception. The test extract also reduced the edema induced in rats using
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50

Rabie, Dalia, and Salah I. Kheder. "Assessment of Prescribing and Dispensing Practices Based on WHO Core Prescribing Indicators in Hospital and Community Pharmacies in Khartoum State - Sudan." Journal of Medical Informatics and Decision Making 1, no. 3 (2020): 1–11. http://dx.doi.org/10.14302/issn.2641-5526.jmid-20-3493.

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Background Rational drug management has become an increasingly important topic in order to make optimal use of the drug budget to offer health services of the highest possible standard. It is important that continuous assessment for rational prescribing and use of drug have to be carried. Objective of this study was to gather data on existing drug prescription and dispensing practices and to evaluate the prescribing and dispensing indicators as described by the WHO. Method Observational, cross-sectional, prospective study was designed and conducted to evaluate the performance of hospital and c
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