Journal articles: 'Standard IPMA'

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Gabardo, Michelle P., José Paulo H. Sato, Talita P. Resende, Luisa V. A. Otoni, Lucas A. Rezende, Amanda G. S. Daniel, Carlos E. R. Pereira, and Roberto M. C. Guedes. "Use of oral fluids to detect anti Lawsonia intracellularis antibodies in experimentally infected pigs." Pesquisa Veterinária Brasileira 40, no. 12 (December 2020): 970–76. http://dx.doi.org/10.1590/1678-5150-pvb-6679.

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ABSTRACT: Several pathogens and antibodies derived from serum or produced in tissues associated with the oral cavity are present in the oral fluid (OF). Considering the applicability of this alternative sample, recent studies in veterinary medicine have tested OF as a replacement for serum in diagnostic assays. The aim of this study was to standardize the immunoperoxidase monolayer assay (IPMA) to detect anti-Lawsonia intracellularis immunoglobulin A (IgA) and immunoglobulin G (IgG) in OF samples from experimentally infected pigs. Sixty-two pigs were divided into two groups: control (T1, n=30) and inoculated with L. intracellularis (T2, n=32). Blood, OF and fecal samples were collected at 0, 7, 14, 21, 28 and 42 days post-inoculation (dpi). Some adaptations of the standard technique for serum were made to IPMA for the detection of IgA and IgG in OF. The IPMA showed high specificity and sensitivity for serum samples and high specificity and moderate sensitivity for the detection of IgA and IgG in OF. There was high agreement between the results of serum IgG and OF IgA and IgG. Based on our results, oral fluid samples may be used for the evaluation and determination of anti-L. intracellularis antibodies in pigs, but not for individual diagnosis of swine proliferative enteropathy.

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Vukomanović, Mladen, Michael Young, and Sven Huynink. "IPMA ICB 4.0 — A global standard for project, programme and portfolio management competences." International Journal of Project Management 34, no. 8 (November 2016): 1703–5. http://dx.doi.org/10.1016/j.ijproman.2016.09.011.

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Gim, Gabriel C. W., and Wen-Sing Cheah. "PAY SATISFACTION AND ORGANISATIONAL TRUST: AN IMPORTANCE-PERFORMANCE MAP ANALYSIS." Journal of Applied Structural Equation Modeling 4, no. 1 (January 1, 2020): 1–16. http://dx.doi.org/10.47263/jasem.4(1)01.

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Using social exchange theory and equity theory, this paper examined the relationship between the four dimensions of pay satisfaction and organisational trust among Malaysian employees. The four dimensions of pay satisfaction are pay benefit satisfaction, pay level satisfaction, pay raise satisfaction,and pay structure and administration satisfaction. Questionnaires were distributed to Malaysians working in several industries. Partial least squares structural equation modeling (PLS-SEM) was used to assess both the measurement and structural model. Results from the structural model revealed that pay benefit satisfaction, pay raise satisfaction, and pay structure and administration satisfaction were positively related to organisational trust. To complement the standard structural model assessment, robustness checks were performed on the structural model in terms of non-linear effects, endogeneity, and unobserved heterogeneity. The checks concluded that there were no issues with regards to nonlinear effects and unobserved heterogeneity. However, the endogeneity test indicated that pay structure and administration satisfaction could be endogenous. Importance-performance map analysis (IPMA) was also performed to gauge the importance and performance of each dimension of pay satisfaction against organisational trust. The IPMA results revealed that pay structure and administration satisfaction was the most important factor yet it attained the lowest score on performance indicating that organisations in Malaysia should make an improvement to their pay structure and administration satisfaction.

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Zevallos, Germán Gallardo, Tatiana Machicao, and María Josée Martínez-Echevarría Romero. "Assessment of highway infrastructure projects in Latin America and Perú from the competences point of view." Organization, Technology and Management in Construction: an International Journal 9, no. 1 (January 27, 2017): 1537–46. http://dx.doi.org/10.1515/otmcj-2016-0016.

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AbstractIt is stressed that Latin America and Perú should become more competitive. Under the actual development scenarios, attention to competences of programme managers and project managers related to public transportation infrastructure projects has risen substantially.An inefficient bureaucratic system is related with deficiencies of people skills and competences. On the other hand, an excellent system demands quality of the system and quality of people working in it.Thus, it is important to have excellence in administration and excellent administrators in the public sector. Three main lacking elements have been identified: i) lack of good education; ii) absence of fair salaries in the public sector; and iii) lack of incentives. Many misconceptions and disputed consequences have been observed and analyzed. It is clear that there is lack of competence among infrastructure transport project managers and teams, which causes trouble with the main goal of Peru getting benefits from these investments and achieving sustainable development. Furthermore, the right way to achieve these benefits is through a new model of education for project managers and programme managers in Perú. This education should be based more on competences than on qualifications. Thus, the International Project Management Association (IPMA) competence baseline, which is the standard that best fits to these needs, needs to be implemented to achieve the real contribution and benefits of these projects to society.

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Ludwig, E., S. H. Olson, R. C. Kurtz, J. Simon, M. F. Brennan, W. R. Jarnagin, and P. J. Allen. "A matched analysis comparing the epidemiology of intraductal papillary mucinous neoplasms to standard pancreatic adenocarcinoma and healthy controls." Journal of Clinical Oncology 29, no. 4_suppl (February 1, 2011): 173. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.173.

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173 Background: The epidemiology of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas is poorly defined. Methods: An epidemiologic questionnaire was administered to patients (pts) with IPMN (n=79), pancreatic adenocarcinoma (PC) (n=689) and healthy controls (n=307). Results were adjusted for age, gender and BMI. IPMN was defined either by surgical pathology (n=62) or characteristic endoscopic ultrasound appearance and cyst fluid CEA>200 ng/ml (n=17). Results: In unadjusted analysis IPMN pts were more likely to be ≥ 70 years of age (OR 5.40 [2.88, 10.46]) when compared with PC pts (OR 2.82) and controls. After adjustment for age, gender and BMI, current tobacco smoking was associated with PC (OR 3.06 [1.78, 5.23]) but not IPMN. Pts with IPMN more often had diabetes mellitus for >3 years compared with controls (OR 3.25 [1.45, 7.00], while pts with PC (OR 1.52 (0.86, 2.67]) did not. IPMN pts were more likely to have a history of hypercholesterolemia compared with controls (OR 1.77 [1.05-2.98]); this was not seen for PC pts (OR 1.16 [0.87-1.55]). A first degree relative with PC was not associated with increased risk for IPMN (OR 0.84 [0.27, 2.62]) or PC (OR 1.48 [0.82, 2.67]). Compared to PC, pts with IPMN were more likely to have a history of an unrelated cancer (OR 1.84 [1.08, 3.14]). Conclusions: Risk factors for IPMN and PC may differ. Compared to PC and control pts, IPMN patients were older; more often had diabetes mellitus and hypercholesterolemia; and did not currently smoke. IPMN was more often associated with a prior history of cancer than PC. No significant financial relationships to disclose.

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Brown, Lance, Jessica Sims, and Alessandra Conforto. "Posterior myocardial infarction with isolated ST elevations in V8 and V9: Is this an “ST elevation MI”?" CJEM 5, no. 02 (March 2003): 115–18. http://dx.doi.org/10.1017/s1481803500008265.

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ABSTRACT We report a case of a 53-year-old man whose first manifestation of coronary artery disease was an acute isolated posterior myocardial infarction (IPMI). Acute IPMI is relatively uncommon and predominantly due to occlusion of the left circumflex coronary artery. IPMI is challenging to diagnose due to the absence of ST segment elevation on a standard 12-lead electrocardiogram (ECG) even in the setting of total coronary artery occlusion and transmural (Q-wave) infarct. We discuss the diagnostic implications of the absence of tall R waves in leads V1 and V2 on this patient’s ECG. The utility of posterior leads (V7 through V9) is demonstrated. The controversy surrounding the use of thrombolytic therapy or primary angioplasty in the setting of acute IPMI without ST segment elevation on a standard 12-lead ECG is reviewed.

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Poveda-Bautista, Rocio, Jose-Antonio Diego-Mas, and Diego Leon-Medina. "Measuring the Project Management Complexity: The Case of Information Technology Projects." Complexity 2018 (2018): 1–19. http://dx.doi.org/10.1155/2018/6058480.

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Complex projects require specific project management (PM) competences development. However, while no complex projects have standards that are recognized to guide their management, complex projects do not have guides to deal with their complexity. To lead complex projects to success, this complexity must be measured quantitatively and, in our opinion, project management complexity assessment should be based on existing PM standards. In this work, the main project complexity assessment approaches based on PM standards are analyzed, observing that International Project Management Association (IPMA) approach is the closest to a tool that can be used as a complexity quantitative measurement system. On the other hand, several authors have shown that the inherent complexity of specific kind of projects must be measured in a particular way. The main objective of this research is to propose a project management complexity assessment tool for IT projects, providing a Complexity Index that measures the impact that complexity factors inherent to IT projects have under a specific complexity scenario. The tool combines the use of complexity factors defined by IPMA approach and the use of complexity factors found in the literature to manage inherent complexity of IT projects. All these factors were validated by expert survey and the tool was applied to a study case.

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Susanti, Siti, Anang Mohamad Legowo, Nurwantoro Nurwantoro, Silviana Silviana, and Fahmi Arifan. "Comparing the Chemical Characteristics of Pectin Isolated from Various Indonesian Fruit Peels." Indonesian Journal of Chemistry 21, no. 4 (April 30, 2021): 1057. http://dx.doi.org/10.22146/ijc.59799.

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The Indonesian pectin manufacturing industry is underdeveloped, and pectin is imported to meet its increasing demand; we attempted to isolate pectins from various fruit peels, such as orange peel (OP), papaya peel (PP), mango peel (MP), watermelon peel (WP), and chayote peel (CP) and investigated their chemical characteristics (equivalent weight of the extracted pectins and their moisture, ash, methoxyl, and galacturonic acid (GA) contents). Acid extraction, purification, precipitation, and drying processes were used to process the isolated pectins. We examined their chemical properties for conformance to quality standards advised by the International Pectin Producers Association (IPPA). The moisture (except OP pectin) and ash contents (except PP pectin) of the extracted pectins were within the limit set by IPPA. However, the equivalent weight (W eq) of any of the isolated pectins did not satisfy IPPA standards. The methoxyl contents of the pectins isolated from OP, WP, and CP satisfied IPPA standards. High methoxyl pectins were isolated from PP and MP. The galacturonic acid contents of the isolated pectins were higher than the acceptable limit of the GA level. Thus, OP, PP, MP, WP, and CP are potential sources of pectin.

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Box, Hayden N., Timothy S. Brown, Michael H. Huo, and Richard E. Jones. "The two-stage standard: Res ipsa loquitur." Seminars in Arthroplasty 26, no. 2 (June 2015): 84–90. http://dx.doi.org/10.1053/j.sart.2015.08.011.

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Ohno, Riki, Ryuichi Kawamoto, Mami Kanamoto, Jota Watanabe, Masahiko Fujii, Hiromi Ohtani, Masamitsu Harada, Teru Kumagi, and Hideki Kawasaki. "Neutrophil to Lymphocyte Ratio is a Predictive Factor of Malignant Potential for Intraductal Papillary Mucinous Neoplasms of the pancreas." Biomarker Insights 14 (January 2019): 117727191985150. http://dx.doi.org/10.1177/1177271919851505.

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Intraductal papillary mucinous neoplasms (IPMNs) are cystic neoplasms with the potential for progression to pancreatic cancer. Accurate prediction of the malignant potential is challenging and a proper treatment strategy has not been well established. Preoperative neutrophil-to-lymphocyte ratio (NLR) is a biomarker of the malignant potential in patients with several types of malignancy. We explored malignant potential in patients with IPMN. The present study included 56 patients aged of 73 ± 9 years (mean ± standard deviation) who underwent curative resection for IPMN from 1996 to 2017. We analyzed the relationship between the characteristics including NLR and malignant component for predicting pathological results. The nonmalignant IPMN group (N = 21) included patients with low-grade dysplasia (LGD) and intermediate-grade dysplasia (IGD), and the malignant IPMN group (N = 35) included patients with high-grade dysplasia (HGD) and invasive carcinoma. In a univariate analysis, NLR ⩾ 2.2 ( P = .001), prognostic nutritional index (PNI) < 45 ( P = .016), CA 19-9 > 37 U/mL ( P = .039), and cystic diameter ⩾ 30 mm ( P = .010), and mural nodule ( P = .010) were significantly different between the malignant IPMN and the nonmalignant IPMN groups. Multivariate analysis showed that high NLR (⩾2.2) (odds ratio 9.79; 95% confidence interval: 2.06-45.6), cystic diameter ⩾ 30 mm (4.65; 1.14-18.9), and mural nodule (4.91; 1.20-20.1) were independently predictive of malignant IPMN. These results suggest that preoperative NLR is a useful predictive biomarker for evaluating malignant potential in patients with IPMN.1

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Titarenko, Boris, Sergey Titov, and Roman Titarenko. "Risk Management in Innovation Projects." Applied Mechanics and Materials 638-640 (September 2014): 2338–41. http://dx.doi.org/10.4028/www.scientific.net/amm.638-640.2338.

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The report deals with projects risk management approaches and methods. The methods are based upon the main provisions of the following standards: International Competence Baseline, published by International Project Management Association – IPMA and National Competence Baseline published by Russian Project Management Association – SOVNET. It is known two types of risk management methods: qualitative and quantitative. Qualitative methods deal with procedures that reduce the risk of risk situations and the quantitative methods allow to produce quantitative estimates of the proposed activities using SOVNET system methodology.

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주한나 and 이희진. "Standards Cooperation and Aid for Trade: Cases of EU and Unites States and their implications to Korean standards policies." Public Policy Review 28, no. 3 (September 2014): 27–52. http://dx.doi.org/10.17327/ippa.2014.28.3.002.

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Shen, Yue, Muhammad Abubakar, Hui Liu, and Fida Hussain. "Power Quality Disturbance Monitoring and Classification Based on Improved PCA and Convolution Neural Network for Wind-Grid Distribution Systems." Energies 12, no. 7 (April 3, 2019): 1280. http://dx.doi.org/10.3390/en12071280.

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The excessive use of power semiconductor devices in a grid utility increases the malfunction of the control system, produces power quality disturbances (PQDs) and reduces the electrical component life. The present work proposes a novel algorithm based on Improved Principal Component Analysis (IPCA) and 1-Dimensional Convolution Neural Network (1-D-CNN) for detection and classification of PQDs. Firstly, IPCA is used to extract the statistical features of PQDs such as Root Mean Square, Skewness, Range, Kurtosis, Crest Factor, Form Factor. IPCA is decomposed into four levels. The principal component (PC) is obtained by IPCA, and it contains a maximum amount of original data as compare to PCA. 1-D-CNN is also used to extract features such as mean, energy, standard deviation, Shannon entropy, and log-energy entropy. The statistical analysis is employed for optimal feature selection. Secondly, these improved features of the PQDs are fed to the 1-D-CNN-based classifier to gain maximum classification accuracy. The proposed IPCA-1-D-CNN is utilized for classification of 12 types of synthetic and simulated single and multiple PQDs. The simulated PQDs are generated from a modified IEEE bus system with wind energy penetration in the balanced distribution system. Finally, the proposed IPCA-1-D-CNN algorithm has been tested with noise (50 dB to 20 dB) and noiseless environment. The obtained results are compared with SVM and other existing techniques. The comparative results show that the proposed method gives significantly higher classification accuracy.

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junseopshim, 윤태섭, and 김지수. "Analysis of Social Demands on Civil Life Standards." Public Policy Review 28, no. 3 (September 2014): 265–98. http://dx.doi.org/10.17327/ippa.2014.28.3.011.

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Ishii, Hiroaki, Kazushige Kawai, Keisuke Hata, Yasutaka Shuno, Takeshi Nishikawa, Toshiaki Tanaka, Junichiro Tanaka, et al. "Comparison of Functional Outcomes of Patients Who Underwent Hand-Sewn or Stapled Ileal Pouch-Anal Anastomosis for Ulcerative Colitis." International Surgery 100, no. 7-8 (November 1, 2015): 1169–76. http://dx.doi.org/10.9738/intsurg-d-15-00012.1.

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Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the standard surgical treatment for patients with ulcerative colitis (UC). The purpose of this study was to investigate the long-term functional outcomes and quality of life (QOL) associated with hand-sewn and stapled IPAA. Ninety-one patients with UC had undergone IPAA using hand-sewn anastomosis with mucosectomy (32 patients) or stapled anastomosis (59 patients) from January 1988 to May 2010. Patients were evaluated according to patient characteristics, postoperative complications, functional outcomes and QOL. The QOL of patients were evaluated using the Medical Outcomes Study Short Form 36 (SF-36) and the Inflammatory Bowel Disease Questionnaire (IBDQ). Numbers of patients with colorectal cancer or dysplasia were significantly greater in the hand-sewn IPAA group (P < 0.01). These patients had longer disease durations and were older (both P < 0.01). There was no difference in the incidence of complications between the groups, except for a greater incidence of postoperative anal fistula in the stapled group (P = 0.03). In the early postsurgery period, both the frequency of bowel movements and the rate of soiling were significantly higher in the hand-sewn group, but in a later period, there was no difference in these events >3 years after surgery. The SF-36 and IBDQ results were similar in the two groups, indicating that hand-sewn and stapled IPAA result in similar QOL in the late postoperative period. Postoperative complications, functional outcomes, and long-term QOL were similar in patients who had received hand-sewn or stapled IPAA.

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Sangbae Kim. "U.S.-China Standard Competition in Cyber Security: A Network Perspective of World Politics." Public Policy Review 28, no. 3 (September 2014): 237–63. http://dx.doi.org/10.17327/ippa.2014.28.3.010.

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Seo, Jeoung-Seoup, 윤태섭, and 주운현. "A Study on the Legalization of Standard-aid Rate of Grants-in-aid Programs: Focusing on Definition and Legalization Way of Standard-aid Rate to Obligatory Grants-in-aid Programs." Public Policy Review 30, no. 3 (September 2016): 61–90. http://dx.doi.org/10.17327/ippa.2016.30.3.003.

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Ragupathi, Madhu, Chirag B. Patel, Diego I. Ramos-Valadez, and Eric M. Haas. "Robotic-Assisted Laparoscopic “Salvage” Rectopexy for Recurrent Ileoanal J-Pouch Prolapse." Gastroenterology Research and Practice 2010 (2010): 1–4. http://dx.doi.org/10.1155/2010/790462.

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Total restorative proctocolectomy with ileal pouch-anal anastomosis (RP/IPAA) has become the standard of care for the surgical treatment of ulcerative colitis. Despite its correlation with an excellent quality of life and favorable long-term outcomes, RP/IPAA has been associated with several complications. Prolapse of the ileoanal pouch is a rare and debilitating complication that should be considered in the differential diagnosis of pouch failure. Limited data exist regarding the prevalence and treatment of pouch prolapse. We present the case of a recurrent J-pouch prolapse treated with a novel minimally invasive “salvage” approach involving a robotic-assisted laparoscopic rectopexy with mesh.

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Nyabanga, Custon, Jordan Axelrad, Xian Zhang, Edward Barnes, Robert Sandler, and Shannon Chang. "P035 ADJUNCT PHARMACOTHERAPY USE FOR POUCH-RELATED SYMPTOMS IN PATIENTS WITH ILEAL POUCH-ANAL ANASTOMOSIS." Inflammatory Bowel Diseases 26, Supplement_1 (January 2020): S59—S60. http://dx.doi.org/10.1093/ibd/zaa010.152.

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Abstract Background For patients with recalcitrant ulcerative colitis or indeterminate colitis, surgical intervention with restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) has become the standard of therapy. The most common complication after IPAA is pouchitis, which may manifest with pouch related symptoms (PRS) such as increased bowel frequency, abdominal pain, pelvic pain, urgency, or incontinence, necessitating use of adjunctive pharmacotherapies for symptom control. We evaluated the prevalence of opioid-, NSAID-, and probiotic-use among IPAA patients with and without PRS. Methods Utilizing patient questionnaires from the IBD Partners database cohort of patients with IPAA, we examined baseline characteristics, antibiotic and biologic use, adjunct pharmacotherapy use, and patient reported outcomes (PROs) including bowel frequency, urgency of defecation, and general well-being. We used specific Patient-Reported Outcome Measurement Information System (PROMIS) measures (measured in T-scores) to assess abdominal pain and depression. Bivariate analysis of baseline demographics and medication use patterns was performed to compare IPAA patients with PRS and without PRS. Among patients with PRS, PROs were compared among opioid, NSAID, and probiotic users. Results We identified 363 patients with IPAA patients in the IBD Partners database, and 266 (73%) reported PRS within 6 months of completing their last survey. In comparison to those without PRS, patients with significant PRS had a shorter time since diagnosis of IBD (P = 0.015), higher prevalence of antibiotic use (P < 0.05), higher rectal steroid use (P = 0.003), and more prevalent adalimumab use (P = 0.041). Among patients with PRS, there were no significant differences in PROs based on NSAID or probiotic usage. However, opiate users with PRS noted increased bowel frequency, urgency of defecation, poor general well-being, abdominal pain, and depression (P < 0.05 for all variables). Conclusion Among IBD patients with IPAA with PRS, the use of NSAIDS and probiotics was not associated with differences in PROs. Opioid use was associated with higher burden of PRS, but further studies will be required to elucidate association or causality.

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Simonetti, Francesco R., Jennifer A. White, Camille Tumiotto, Kristen D. Ritter, Mian Cai, Rajesh T. Gandhi, Steven G. Deeks, et al. "Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA." Proceedings of the National Academy of Sciences 117, no. 31 (July 20, 2020): 18692–700. http://dx.doi.org/10.1073/pnas.2006816117.

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A scalable approach for quantifying intact HIV-1 proviruses is critical for basic research and clinical trials directed at HIV-1 cure. The intact proviral DNA assay (IPDA) is a novel approach to characterizing the HIV-1 reservoir, focusing on the genetic integrity of individual proviruses independent of transcriptional status. It uses multiplex digital droplet PCR to distinguish and separately quantify intact proviruses, defined by a lack of overt fatal defects such as large deletions and APOBEC3G-mediated hypermutation, from the majority of proviruses that have such defects. This distinction is important because only intact proviruses cause viral rebound on ART interruption. To evaluate IPDA performance and provide benchmark data to support its implementation, we analyzed peripheral blood samples from 400 HIV-1+adults on ART from several diverse cohorts, representing a robust sample of treated HIV-1 infection in the United States. We provide direct quantitative evidence that defective proviruses greatly outnumber intact proviruses (by >12.5 fold). However, intact proviruses are present at substantially higher frequencies (median, 54/106CD4+T cells) than proviruses detected by the quantitative viral outgrowth assay, which requires induction and in vitro growth (∼1/106CD4+T cells). IPDA amplicon signal issues resulting from sequence polymorphisms were observed in only 6.3% of individuals and were readily apparent and easily distinguished from low proviral frequency, an advantage of the IPDA over standard PCR assays which generate false-negative results in such situations. The large IPDA dataset provided here gives the clearest quantitative picture to date of HIV-1 proviral persistence on ART.

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Логинова, Екатерина, and Ekaterina Loginova. "Project Manager’s Competencies in Renewable Energy Projects." Scientific Research and Development. Russian Journal of Project Management 6, no. 3 (October 26, 2017): 19–25. http://dx.doi.org/10.12737/article_59e8ab4c61d0e0.92107203.

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This research examines renewable energy (RE) project manager competencies required by USA labor market using the analyses of project manager Internet job advertisements. It was realized by collecting and coding the requirements from the job advertisements in April 2017. 1500 vacancies were found by the website, but only 150 of them were relevant for this work (they were filtered according to some formal criteria). From the data obtained from advertisement analyses, the pool of job candidate’s competencies required by the market was compiled. The most common requirements were compared with IPMA and SOVNET competency standards for project managers. The research shows that companies are seeking a candidate with bachelor degree in engineering, project management and specific sectorial certificates, 6 years of professional experience related to project management. Some competencies coincide with the standards and the other are referred to specific RE skills.

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Wu, Xian-rui, Hao-xian Ke, Ravi P. Kiran, Bo Shen, and Ping Lan. "Continent Ileostomy as an Alternative to End Ileostomy." Gastroenterology Research and Practice 2020 (January 10, 2020): 1–9. http://dx.doi.org/10.1155/2020/9740980.

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Continent ileostomy (CI) was once a prevalent surgical technique for patients who required total proctocolectomy but then gave way to ileal pouch-anal anastomosis (IPAA) after 1980. Although IPAA has been the gold standard procedure preferred by most patients when total proctocolectomy is required, due to its imitation of physiological function of rectum and preserved function of anus, various complications have been observed with a relatively high rate of morbidity that could affect pouch longevity. Once serious complications such as pelvic abscesses and/or fistula occur, the pouch often needs to be removed. In addition, for some patients with a shortened small intestine or foreshortened mesentery, it is impossible for the ileal pouch to reach the pelvic floor, thus making the creation of an IPAA difficult. Previously, most of these patients would be referred for an end ileostomy, with an associated poor quality of life. In this circumstance, we propose that CI may deserve a reappraisal and serve as an alternative. In this article, we review the indications, contraindications, technique evolution, and outcomes of CI.

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Castiglia, Riccardo, Ernesto Capanna, Alexandra M. R. Bezerra, Domenico Bizzoco, Emanuela Zambigli, and Emanuela Solano. "New Metacentric Populations and Phylogenetic Hypotheses Involving Whole-Arm Reciprocal Translocation in Mus musculus domesticus from Sicily, Southern Italy." Cytogenetic and Genome Research 146, no. 3 (2015): 230–37. http://dx.doi.org/10.1159/000439208.

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The house mouse Mus musculus domesticus is characterized by more than 100 metacentric populations, due to the occurrence of Robertsonian (Rb) fusions, together with the standard all-telocentric karyotype (2n = 40). We examined G-banded karyotypes of 18 mice from 10 localities in Sicily and describe 3 new metacentric populations: ‘Ragusa Ibla' (IRAG), 2n = 33-36, Rb(2.4), Rb(5.6), Rb(9.16), Rb(13.17); ‘Piana degli Albanesi' (IPIA), 2n = 23, Rb(1.18), Rb(2.15), Rb(3.5), Rb(4.12), Rb(6.11), Rb(7.8), Rb(9.16), Rb(10.14), Rb(13.17); ‘Trapani' (ITRA), 2n = 22, Rb(1.18), Rb(2.15), Rb(3.7), Rb(4.12), Rb(5.9), Rb(6.11), Rb(8.16), Rb(10.14), Rb(13.17). Three mice belonged to the previously reported ‘Castelbuono' race (ICAS), 2n = 24, which is very similar to the nearby ‘Palermo' (IPAL) race, 2n = 26. Three Rb fusions not yet observed in wild mouse populations were identified: Rb(3.5), Rb(3.7) and Rb(5.9). Rb fusions shared among 4 races (IPIA, IRAG, ICAS, and IPAL) allowed us to describe their potential phylogenetic relationships. We obtained 2 alternative phylogenetic trees. The differences between them are mainly due to various modes of formation of IPIA and ITRA. In the first hypothesis, the specific Rb fusions occurred independently. In the second, those of IRAG originated from those of IPIA via whole-arm reciprocal translocations.

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최동근. "Comparing National Governance of Korea and USAfor Using Standards in Technical Regulations." Public Policy Review 28, no. 3 (September 2014): 97–121. http://dx.doi.org/10.17327/ippa.2014.28.3.005.

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Roch, Alexandra M., Michael Garrett House, Neil R. Sharma, Jessica L. Cioffi, John M. DeWitt, Jeffrey J. Easler, Eugene P. Ceppa, Nicholas J. Zyromski, Attila Nakeeb, and C. Max Schmidt. "Cytology from endoscopic retrograde cholangiopancreatography in the evaluation of invasive pancreatic head intraductal papillary mucinous neoplasm: A necessity?" Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): 266. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.266.

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266 Background: Endoscopic retrograde cholangiopancreatography (ERCP) with brushing/fluid sampling has historically been the standard to establish invasive transformation of pancreatic head intraductal papillary mucinous neoplasm (IPMN). More recently, endoscopic ultrasound (EUS) with fine needle aspiration (FNA) has been employed for this purpose. We hypothesized that for patients with invasive IPMN, in the era of EUS FNA, there is no additional benefit of ERCP brushing/fluid sampling. Methods: A retrospective review of a prospectively maintained database of patients who underwent surgical resection for IPMN at a single academic center (1992-2014) was performed. Patients with invasive pancreatic head IPMN on surgical pathology were included. Cytopathology was considered positive if it showed adenocarcinoma or markedly atypical cells. Results: Of the 74 patients with invasive IPMN, 55 had a pancreatic head neoplasm. Preoperatively, 4 patients had neither EUS nor ERCP, 27 had only 1 endoscopic study (ERCP n=16, EUS n=11), and 24 had both EUS and ERCP. In 11 patients with EUS, 8 had positive FNA (73% sensitivity for cancer detection). In 16 patients with ERCP (brushing n=7, fluid n=9), 5 had positive cytology resulting in 31% sensitivity. Further analysis revealed 29% and 33% sensitivity for brushing and fluid sampling, respectively. When both procedures were performed (n=24; EUS+ERCP fluid n=10, EUS+ERCP brushing n=14), the sensitivity was 75%, but ERCP cytology changed the diagnosis in only 2 patients. EUS FNA was performed regardless of ERCP cytology results in 18 patients (after brushing n=6, after fluid sampling n=4, same day n=8; median interval=4 days). 6 patients had negative cytology from both EUS and ERCP. Conclusions: In patients with invasive pancreatic head IPMN, sensitivity of ERCP cytology for cancer detection was poor (31%), making an impact on diagnosis in only 2/55 patients. EUS FNA was performed in 75% patients regardless of ERCP cytology results. Aside from the therapeutic impact of ERCP (biliary endoprosthesis in jaundiced patients), its cytological role is limited, resulting in unnecessary and potentially avoidable cost.

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Tonyali, Senol, Cavit Ceylan, Erdogan Aglamis, Serkan Dogan, Sedat Tastemur, and Mustafa Karaaslan. "Is there a PSA cut-off value indicating incidental prostate cancer in patients undergoing surgery for benign prostatic hyperplasia?" Archivio Italiano di Urologia e Andrologia 93, no. 1 (March 18, 2021): 31–34. http://dx.doi.org/10.4081/aiua.2021.1.31.

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Aim: To investigate incidental prostate cancer (IPCa) rate and to determine prostate specific antigen (PSA) cut-off value indicating PCa in patients who underwent surgery by being diagnosed with benign prostatic hyperplasia (BPH) clinically or by standard prostate biopsy. Methods: Data of 317 patients, who underwent transurethral resection of the prostate (TURP) or open prostatectomy (OP) with pre-diagnosis of BPH, were evaluated retrospectively. The examined parameters included patients’ demographics, preoperative serum PSA values, digital rectal examination (DRE) findings, surgical method, histopathological findings and Gleason Scores.Results: A total of 317 patients were included the study. The median age of patients was 69 years (min: 51-max: 79) and the median PSA value was 3.24 ng/dl (min: 0.17-max: 34.9). In 21 patients (6.6%); DRE findings were in favor of malignancy, but prostate biopsy resulted as BPH. While 281 (88.6%) of the patients underwent TURP, 36 (11.4%) underwent open prostatectomy. PCa was detected in 21 (6.6%) patients. PSA was statistically higher in patients who underwent OP compared to patient who underwent TUR-P, 5.9 (min: 1.2 - max: 27.6, IR: 8.7) vs. 2.8 (min: 0.1-max: 34.9, IR: 4.2) ng/dl, p < .001. The rate of IPCa among four PSA group was similar (p = 0.46). There was no difference between the rate of IPCa in patients younger and older than 70 years, (p = 0.11). Please change whole sentence as 'The median PSA level was slightly higher in patients diagnosed with BPH compared to patients diagnosed with IPCa, 3.2 (min: 0.1-max: 34.9) vs. 2.7 (min: 0.3-max: 26.5) ng/dL, p = 0.9. Conclusions: IPCa still remains an important clinical problem. We were not able to find any correlation of PSA and age with incidental PCa.

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Henninger, Benjamin, Michael Steurer, Michaela Plaikner, Elisabeth Weiland, Werner Jaschke, and Christian Kremser. "Magnetic resonance cholangiopancreatography with compressed sensing at 1.5 T: clinical application for the evaluation of branch duct IPMN of the pancreas." European Radiology 30, no. 11 (June 18, 2020): 6014–21. http://dx.doi.org/10.1007/s00330-020-06996-2.

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Abstract Objectives To evaluate magnetic resonance cholangiopancreatography (MRCP) with compressed sensing (CS) for the assessment of branch duct intraductal papillary mucinous neoplasm (BD-IPMN) of the pancreas. For this purpose, conventional navigator-triggered (NT) sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE) MRCP was compared with various CS-SPACE-MRCP sequences in a clinical setting. Methods A total of 41 patients (14 male, 27 female, mean age 68 years) underwent 1.5-T MRCP for the evaluation of BD-IPMN. The MRCP protocol consisted of the following sequences: conventional NT-SPACE-MRCP, CS-SPACE-MRCP with long (BHL, 17 s) and short single breath-hold (BHS, 8 s), and NT-CS-SPACE-MRCP. Two board-certified radiologists evaluated image quality, duct sharpness, duct visualization, lesion conspicuity, confidence, and communication with the main pancreatic duct in consensus using a 5-point scale (1–5), with higher scores indicating better quality/delineation/confidence. Maximum intensity projection reconstructions and originally acquired data were used for evaluation. Wilcoxon signed-rank test was used to compare the intra-individual difference between sequences. Results BHS-CS-SPACE-MRCP had the highest scores for image quality (3.85 ± 0.79), duct sharpness (3.81 ± 1.05), and duct visualization (3.81 ± 1.01). There was a significant difference compared with NT-CS-SPACE-MRCP (p < 0.05) but no significant difference to the standard NT-SPACE-MRCP (p > 0.05). Concerning diagnostic quality, BHS-CS-SPACE-MRCP had the highest scores in lesion conspicuity (3.95 ± 0.92), confidence (4.12 ± 1.08), and communication (3.8 ± 1.06), significantly higher compared with NT-SPACE-MRCP, BHL-SPACE-MRCP, and NT-CS-SPACE-MRCP (p = <0.05). Conclusions MRCP with CS 3D SPACE for the evaluation of BD-IPMN at 1.5 T provides the best results using a short breath-hold sequence. This approach is feasible and an excellent alternative to standard NT 3D MRCP sequences. Key Points • 1.5-T MRCP with compressed sensing for the evaluation of branch duct IPMN is a feasible method. • Short breath-hold sequences provide the best results for this purpose.

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Wasmann, Karin A., Maud A. Reijntjes, Merel E. Stellingwerf, Cyriel Y. Ponsioen, Christianne J. Buskens, Roel Hompes, Pieter J. Tanis, and Willem A. Bemelman. "Endo-sponge Assisted Early Surgical Closure of Ileal Pouch-anal Anastomotic Leakage Preserves Long-term Function: A Cohort Study." Journal of Crohn's and Colitis 13, no. 12 (May 4, 2019): 1537–45. http://dx.doi.org/10.1093/ecco-jcc/jjz093.

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Abstract Background and Aims Endo-sponge [Braun Medical] assisted early surgical closure [ESC] is an effective treatment to control pelvic sepsis after ileal pouch-anal anastomosis [IPAA] leakage, and became standard treatment in our centre from 2010 onwards. The aim of this cohort study was to assess the long-term pouch function of ulcerative colitis [UC] patients treated with ESC or conventional management [CM] for anastomotic leakage after IPAA. Methods Consecutive patients who underwent an IPAA for UC between 2002 and 2017 were included. Patients treated with ESC [2010–2017] or CM [2002–2009] for anastomotic leakage were compared with control patients without anastomotic leakage of the corresponding time period. Main endpoints were long-term pouch function on a 3-point scale and pouch failure, as measured with the validated pouch dysfunction score questionnaire. Results Some 280 of 334 patients [84%] returned the pouch dysfunction questionnaire, of whom 18 were treated with ESC and 22 with CM for anastomotic leakage. Control cohorts included 133 [2010–2017] and 107 patients [2002–2009]. Between ESC-treated patients and control patients, pouch function [p = 0.647] and pouch failure rates [0/18 versus 5/133, p >0.99] were similar. CM resulted in worse pouch function [p = 0.016] and a higher pouch failure rate [5/22 versus 5/107, p = 0.013] compared with control patients. Conclusions ESC, in contrast to CM, for IPAA leakage in UC patients is associated with preservation of pouch function and preclusion of pouch failure, probably due to early and effective treatment of pelvic sepsis.

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Königsrainer, Alfred. "Standard Changing News Onkologie in der Tumorchirurgie." Der Klinikarzt 49, no. 11 (November 2020): 452–55. http://dx.doi.org/10.1055/a-1292-4956.

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ZUSAMMENFASSUNGIm Jahr 2020 haben sich bislang durch die Pandemie viele Veränderungen ergeben und die Gesamtheit der Veränderungen sind noch nicht absehbar, dies nicht nur wegen der öffentlichen Beschränkungen sondern vielmehr wegen der vielschichtigen Einflüsse auf den klinischen Alltag aller Patienten und der onkologischen Versorgung im Besonderen. Die Ergebnisse einer internationalen Datenanalyse zeigen auf, dass im Zeitraum der ersten COVID-19-Welle innerhalb von 9 Wochen weltweit ca. 28 Millionen Eingriffe abgesagt oder verschoben werden mussten 1. Für Deutschland lag die Schätzung bei 900 000 abgesagten oder verschobenen Operationen im gleichen Zeitraum. Dies betraf auch onkologische Operationen, wie ganz rezent in einer Analyse aus Abrechnungsdaten im Deutschen Ärzteblatt vom 6. Juli 2020 aufgezeigt wird 2. Das internationale Konsortium, an dem der Autor dieses Beitrages auch beteiligt ist, untersucht des Weiteren die postoperative Komplikationsrate und die perioperative Mortalität bei SARS-CoV-2-infizierten Patienten 3, aber auch die Einflüsse der Pandemie auf die chirurgische Versorgung von Tumorpatienten (Manuskript im Begutachtungsverfahren). Das erschreckend hohe perioperative Risiko, gerade nach größeren Eingriffen mit einer Pneumonierate von nahezu 50 % und einem Risiko von über 20 % innerhalb von 30 Tagen postoperativ zu versterben, erfordern umfassende Maßnahmen sowie eine Triagierung nahezu aller Tumorpatienten 4. Was dies für unsere Patienten im Einzelnen bedeutet, wird sich erst in den kommenden Monaten/Jahren zeigen.Der Jahresbeitrag beschäftigt sich in diesem Jahr ausschließlich mit dem Pankreaskarzinom und neuen Strategien in der Chirurgie sowie der perioperativen multimodalen Therapie. Zuletzt wird es noch Hinweise zum Management von Vorläuferläsionen wie intraduktaler papillär-muzinöser Neoplasien des Seitengangs (Seitengang-IPMN) geben.

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Król, Konrad. "THE ORETICAL AND METHODOLOGICAL FUNDAMENTALS OF RESEARCH OF ANTI-RISK STAKEHOLDERS OF PROJECT MANAGEMENT." Bulletin of NTU "KhPI". Series: Strategic management, portfolio, program and project management, no. 1(3) (April 17, 2021): 32–38. http://dx.doi.org/10.20998/2413-3000.2021.3.5.

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Projects of the agro-industrial complex are implemented in conditions of high uncertainty and risk. Agricultural products provide variety and quality of food to the population. To reduce production losses and the quality of crop and livestock products, and as a consequence of reducing the economic efficiency of production, it is necessary to take measures to prevent and reduce the risks of agro-industrial projects. Given that the risks associated with stakeholders can have devastating consequences for the project, anti-risk stakeholders of projects management is critical. In connection with the widespread use of international teams for project implementation, the author proposes to take into account when managing stakeholders of projects their mentality, which can be a cause of misunderstandings and conflicts. The author also emphasizes the importance of identifying and managing the expectations of project stakeholders. The article presents the principles of stakeholders of projects management and analyzes the stakeholders of projects management processes in international project management standards, in particular P2M, ICB IPMA, PMBoK PMI and ISO 21500. The author also provides principles of project risk management in accordance with international project management standards, in particular P2M, ICB IPMA, PMBoK PMI and ISO 21500. It was found that the identification and analysis of stakeholders is the basis for understanding what risks associated with each stakeholder may arise during the project. The author emphasizes that it is impossible to analyze the risks associated with them without conducting a detailed analysis of stakeholders. And developing a stakeholder risk response plan depends largely on the characteristics of each particular stakeholder and understanding which leverage can be effective in a given stakeholder. For more effective anti-risk stakeholders of agro-industrial projects management, which would take into account the specific risks of such projects, the author recommends to develop and use tools that would take into account the characteristics of stakeholders involved in agro-industrial projects.

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Sweeney, E. B., J. E. Foley, S. Fitzsimons, and A. Denihan. "To MSNAP or not to MSNAP? Testing a small regional memory clinic against the UK Memory Service National Accreditation Program (MSNAP)." Irish Journal of Psychological Medicine 36, no. 2 (May 3, 2018): 145–51. http://dx.doi.org/10.1017/ipm.2018.14.

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AimTo investigate whether a small regional memory clinic would benefit from engaging with a structured external audit process such as the Royal College of Psychiatrists’ Memory Service National Accreditation Program (MSNAP).BackgroundThe Psychiatry of Old Age service in Navan operates a public cognitive clinic. Despite the publication of the 2014 National Dementia Strategy, there are currently no national standards for memory clinics in Ireland. It may be beneficial to link in with an external quality control system as part of routine clinical governance.MethodsPublished data from the MSNAP group was reviewed and a set of audit materials extrapolated to replicate the MSNAP self-review process. The audit cycle involved (1) retrospective case review, (2) institution of a range of interventions and (3) a prospective audit, which included service user feedback.ResultsOverall the results demonstrated a high standard of service, especially in the areas of accessibility, assessment and communication of diagnosis. The clinic performed well against MSNAP key performance indicators. Patient and carer satisfaction with the service was very high. Clinic policies needed further development, particularly in the areas of referral, consent and data protection.ConclusionsThe process was useful, providing clear pointers for action. It highlighted the need to formalise organisational and practice policies, patient support and education, audit and outreach. Although accreditation is a laborious process requiring financial investment, it provides a strong scaffold to maintain and improve standards and is likely to be a valuable learning experience, where national guidelines are lacking.

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Porreca, Angelo, Daniele D'Agostino, Mario Vigo, Paolo Corsi, Daniele Romagnoli, Alessandro Del Rosso, Riccardo Schiavina, Eugenio Brunocilla, Walter Artibani, and Marco Giampaoli. "“In-bore” MRI prostate biopsy is a safe preoperative clinical tool to exclude significant prostate cancer in symptomatic patients with benign prostatic obstruction before transurethral laser enucleation." Archivio Italiano di Urologia e Andrologia 91, no. 4 (January 14, 2020): 224–29. http://dx.doi.org/10.4081/aiua.2019.4.224.

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Introduction: Purpose of our study was to investigate the role of a negative in-bore MRI-guided biopsy (MRI-GB) in comparison to a negative multiparametric prostate MRI (mpMRI) and a contextual negative transrectal ultrasound guided biopsy of the prostate with regard to incidental prostate cancer findings in the surgical specimen of men who underwent to Holmium Laser enucleation of prostate (HoLEP) with a preoperative suspicion of prostate cancer. Materials and methods: Data of 117 of symptomatic patients for bladder outflow obstruction who subsequently underwent to HoLEP was retrospectively analyzed form a multicentric database. All patients had a raised serum PSA and/or an abnormal digital rectal examination (DRE) with a pre-interventional mpMRI. Prostate cancer was excluded either with an en-bore MRI-GB (group "IN-BORE MRI-GB" n = 57) in case of a suspect area at the mpMRI or with a standard biopsy (group "mpMRI + TRUS-GB" n = 60) in case of a negative mpMRI. Preoperative characteristic surgical and histological outcomes were analyzed. Univariate and multivariate logistic regression model was performed to investigate independent predictors of incidental Prostate Cancer (iPCa). Results: Both groups presented moderate to severe lower tract urinary symptoms: median IPSS was 19 (IQR: 17.0-22.0) in the IN-BORE MRI-GB group and 20 (IQR: 17.5-22.0) in the mpMRI + TRUS-GB (p = 0.71). No statistically significant difference was found between the two groups besides total prostate volume with 68 cc (IQR: 58.0-97.0) in the IN-BORE MRI-GB group and 84 cc (IQR: 70.0-115.0) in the mpMRI + TRU-GB group (p = 0.01) No differences were registered in surgical time, removed tissue, catheterization time, hospital stay and complications rate. No different rates (p = 0.50) of iPCa were found in the IN-BORE MRI-GB group (14%) in comparison with mpMRI + TRUS-GB group (10 %); pT stage and ISUP Grade Group in iPCa stratification were comparable between the two groups. In multivariate analysis a statistically significant correlation with age as an independent predictive factor of iPCa was found (OR 1.14; 95% CI: 1.02-1.27; p = 0.02) while no correlations were revealed with PSA (OR 1.12; 95% CI: 0.99-1.28; p = 0.08) and a negative in-bore MRI-GB (OR 1.72; 95% CI: 0.51-5.77; p = 0.37). Conclusions: Including a mpMRI and an eventual in-bore MRIGB represents a novel clinical approach before surgery in patients with symptomatic obstruction with a concomitant suspicion of PCa, leading to low rate of iPCa and avoiding unnecessary standard TRUS-GB biopsies

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Li, Lin, Naiquan Mao, Yingcheng Lyu, Huayue Lin, Kefeng Wang, Xiaotian He, Wenjian Wang, et al. "The novel approach to distinguish primary multiple lung adenocarcinomas from intrapulmonary metastases by next generation sequencing in Chinese patients." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e20506-e20506. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e20506.

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e20506 Background: Differentiation of multiple primary lung cancer (MPLC) from intrapulmonary metastasis (IPM) is critical to determine clinical stage. Although clinicopathological features could provide certain evidences, it’s still challenging to identify the tumor malignancy accurately. In General, standard histopathologic approach is adequate in most cases, but has notable limitations in the recognition of IPMs. Herein, we propose an integrated molecular algorithm to facilitate MPLCs and IPMs diagnosis in the clinical practice. Methods: 40 Chinese patients with lung adenocarcinomas were enrolled in the study, 84 tumor samples were collected for next-generation sequencing. Somatic alterations with variant allele fraction (VAF) ≥1% were taken into account for molecular algorithm. A genomic database of 2,471 Chinese lung adenocarcinomas (LUAD) was used to calculate odds of coincidental occurrence, prevalence of individual mutation prevalence. Tumor relatedness diagnosed by histopathologic assessment was contrasted with comparative genomic profiling by subsequent NGS. Moreover, the performance of molecular algorithm prediction was evaluated as well. Results: Firstly, we compared the performance of comprehensive next-generation sequencing (NGS) with standard histopathologic approaches for distinguishing NSCLC subtypes in clinical practice. The genomic profiling was described as following: EGFR alterations occurred more frequently in MPLCs compared to IPMs (77.1% vs 50.0%, P<0.05). Further analysis showed that TP53 alterations occurred less frequently in MPLCs compared to large Chinese cohort (22.9% vs 51.0%, P<0.05). TP53 alterations occurred less frequently in MPLCs compared to large Chinese cohort (P<0.05). The classifications based on the three different methodologies mentioned above were compared. Molecular algorithm prediction was concordant with NGS in 21 cases (52.5%), particularly in the prediction of MPLC. Retrospective review highlighted several histologic challenges, including morphologic progression in some IPMs. For the five undetermined cases, two showed differences in architectural patterns, and remained cases have nodules presented as adenocarcinoma in situ, or minimally invasive adenocarcinoma. Of 28 MPLC cases defined by NGS, 25 cases had unique somatic mutations per pair Based on calculation from the prevalence of EGFR L858R mutation (27%) in large Chinese cohort, the odds of coincidental occurrence of the mutation in two unrelated tumors was 7.3%. Taking together, EGFR alterations occurred more frequently in MPLCs compared to IPMs (77.1% vs 50.0%, P<0.05). Molecular algorithm prediction was concordant with NGS in 21 cases (52.5%). Conclusions: Our results support broad panel NGS to assist differential diagnosis to assist approach in clinical practice. It is necessary to conduct large clinical study to establish comprehensive algorithm models to assist diagnosis and predict clinical outcome.

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Papilo, Petir. "Integrasi Metode IPMS dan SMART System Dalam Pengukuran Kinerja Perguruan Tingi." Jurnal Teknik Industri 13, no. 2 (December 28, 2012): 186. http://dx.doi.org/10.22219/jtiumm.vol13.no2.186-193.

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Petir PapiloProgram Studi Teknik Industri – Fakultas Sains dan Teknologi, UIN Sultan Syarif Kasim RiauLaman: pilo_ukm@yahoo.comABSTRAKKajian ini bertujuan untuk mengetahui tingkat pencapaian kinerja pada organisasi pendidikan khususnya dalamlingkup suatu fakultas.Dengan menggunakan metode IPMS telah ditetapkan sebanyak 32 strategi objektif yang ingindicapai yang terangkum kedalam 9 (Sembilan) aspek yang merupakan perspektif-perspektif yang ada pada Model SMARTSystem. Dari analisis prioritas yang telah dilakukan, terdapat lima faktor utama yang menjadi fokus perhatian dan menjadiindikator penentu keberhasilan pencapaian visi dan misi yang telah ditetapkan oleh Fakultas “X”. Dari pengukuran yangtelah dilakukan diperoleh nilai indeks kinerja Fakultas “X” berada pada tingkat 3,72 pada tahun 2011. Mengacu kepadastandar taraf pencapaian yang ada, dapat disimpulkan bahwa pencapaian kinerja Fakultas “X” masih jauh dari targetyang diharapkan, yakni pada taraf antara 8 hingga 9.Kata kunci: Kinerja, Metode IPMS, Model SMART SystemABSTRACTThis study aimed to determine the level of achievement of the organization, performance in education, especiallywithin the scope of a faculty. By using this IPMS method, it has been established over 32 objective strategy to be achievedthat were summarized into 9 (nine) aspects are perspectives that exist on the SMART System Model. From the analysis ofthe priorities that had been made, there are five main factors that became the focus of attention and a critical indicatorof success in achieving the vision and mission set by the “X” Faculty.From the measurements that had been performedFaculty performance index values were 3.72 level. Referod to a standard level of achievement, it could be concluded thatthe achievement of the Faculty “X”, was still far from the expected target, at the 8 to 9 level.Key words: IPMS Method, Performance, SMART System Model

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하대청. "WTO Disputes Settlement and ‘International Standards’ : Focusing on EC-Sardines Case and EC-Biotech Product Case." Public Policy Review 28, no. 3 (September 2014): 53–75. http://dx.doi.org/10.17327/ippa.2014.28.3.003.

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Jung-Hoon Ki. "South and North Korea's Standards Unification to Prepare the Unification Era: Based on Collaborative Governance Models." Public Policy Review 28, no. 3 (September 2014): 149–79. http://dx.doi.org/10.17327/ippa.2014.28.3.007.

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Ariany, Yudistia, Ardi Ardi, and Yosi Laila Rahmi. "Analisis Pemahaman Guru IPA se-Kecamatan Lima Kaum terhadap Pelaksanaan Standar Proses dan Standar Penilaian Kurikulum 2013." JURNAL EKSAKTA PENDIDIKAN (JEP) 2, no. 1 (May 24, 2018): 56. http://dx.doi.org/10.24036/jep/vol2-iss1/134.

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In the 2013 curriculum the learning process uses 21st century skills, while for the assessment process uses authentic assessment. Based on the observation of class VII SMP Negeri in Lima Kaum Tanah Datar district, the teachers in the school have not fully implemented the Curriculum 2013. This resulted in a gap in the compliance of National Education Standards, especially on process standards and assessment standards.The aim of this research is a describe the understanding of science teachers in implementing the 2013 Curriculum in the class VII especially on standard process and assessment standard. This research was conducted in junior high school in Kecamatan Lima Kaum Tanah Datar. The population in this research is science teacher in class VII consisting of 8 science teachers.The sampling technique used is total sampling. Data collection techniques used questionnaires and document analysis. The data obtained were analyzed using percentage technique and made according to the descriptive sub indicator.The results revealed the understanding of science teachers on the implementation of Curriculum 2013 class VII in SMP Negeri Se-Kecamatan Lima Kaum Tanah Datar. 1. Understanding of science teachers on the implementation of Curriculum 2013 based on process standard that is 80,5% with good criteria. 2. Understanding of science teachers on the implementation of Curriculum 2013 based on the standard assessment is 83.4% with good criteria.

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Keating, Patricia A. "IPA Council votes against new IPA symbol." Journal of the International Phonetic Association 42, no. 2 (August 2012): 245. http://dx.doi.org/10.1017/s0025100312000114.

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In June 2011, the IPA Council received a formal request from William Barry and Jürgen Trouvain to vote on the adoption of a standard IPA symbol for the central open (unrounded) vowel. This request followed publication in 2008, in JIPA 38(3), of their paper ‘Do we need a symbol for a central open vowel?’, along with response papers in JIPA 39(2) by Daniel Recasens and Martin Ball, and a further response from Barry and Trouvain, in JIPA 39(3).

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Mattila, Nora, Hanna Seppänen, Harri Mustonen, Beata Przybyla, Caj Haglund, and Riitta Lassila. "Preoperative Biomarker Panel, Including Fibrinogen and FVIII, Improves Diagnostic Accuracy for Pancreatic Ductal Adenocarcinoma." Clinical and Applied Thrombosis/Hemostasis 24, no. 8 (June 4, 2018): 1267–75. http://dx.doi.org/10.1177/1076029618779133.

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Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer often diagnosed late. Earlier detection is urgently needed. Pancreatic ductal adenocarcinoma is known to associate with increased coagulation activity. We studied whether preoperative coagulation biomarkers are useful in distinguishing PDAC from a benign tumor, intraductal papillary mucinous neoplasm (IPMN) in this observational study. We analyzed standard clinical and coagulation variables in patients operated during 2010 and 2015 at Helsinki University Hospital. Pancreatic ductal adenocarcinoma with preoperative coagulation variables available and no neoadjuvant treatment or other active cancer was observed in 80 patients (stage I-III in 67 and IV in 13) and IPMN in 18 patients. Fibrinogen, factor VIII (FVIII), carbohydrate antigen (CA) 19-9, albumin, alkaline phosphatase, and conjugated bilirubin were higher in both stages I to III and IV PDAC compared to IPMN ( P < .05). Factor VIII was highest in stage IV ( P < .05). Combining these variables in a panel increased sensitivity and specificity for PDAC. In receiver operating characteristic analysis, the area under the curve (95% confidence interval) was 0.95 (0.90-1.00) for the panel, compared to 0.80 (0.71-0.88) for CA 19-9 alone ( P < .01). In conclusion, PDAC was associated with increased fibrinogen and FVIII. Combining these coagulation biomarkers with CA 19-9, albumin, and alkaline phosphatase improves diagnostic accuracy.

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Zhu, Yadan, Juxin Yang, Xiao Chen, Xiaopeng Zhu, Junxuan Zhang, Shiguang Li, Yanguang Sun, et al. "Airborne Validation Experiment of 1.57-μm Double-Pulse IPDA LIDAR for Atmospheric Carbon Dioxide Measurement." Remote Sensing 12, no. 12 (June 22, 2020): 1999. http://dx.doi.org/10.3390/rs12121999.

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The demand for greenhouse gas measurement has increased dramatically due to global warming. A 1.57-μm airborne double-pulse integrated-path differential absorption (IPDA) light detection and ranging (LIDAR) system for CO2 concentration measurement was developed. The airborne field experiments of this IPDA LIDAR system were conducted at a flight altitude of approximately 7 km, and the weak echo signal of the ocean area was successfully received. The matched filter algorithm was applied to the retrieval of the weak signals, and the pulse integration method was used to improve the signal-to-noise ratio. The inversion results of the CO2 column-averaged dry-air mixing ratio (XCO2) by the scheme of averaging after log (AVD) and the scheme of averaging signals before log were compared. The AVD method was found more effective for the experiment. The long-term correlation between the changing trends of XCO2 retrieved by the IPDA LIDAR system and CO2 dry-air volume mixing ratio measured by the in-situ instrument reached 92%. In the steady stage of the open area (30 km away from the coast), which is almost unaffected by the residential areas, the mean value of XCO2 retrieved by the IPDA LIDAR system was 414.69 ppm, with the standard deviation being 1.02 ppm. Compared with the CO2 concentration measured by the in-situ instrument in the same period, bias was 1.30 ppm. The flight path passed across the ocean, residential, and mountainous areas, with the mean value of XCO2 of the three areas being 419.35, 429.29, and 422.52 ppm, respectively. The gradient of the residential and ocean areas was 9.94 ppm, with that of the residential and mountainous areas being 6.77 ppm. Obvious gradients were found in different regions.

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Shibles, Warren. "A Comparative Phonetics of Italian toward a Standard IPA Transcription." Italica 71, no. 4 (1994): 548. http://dx.doi.org/10.2307/479670.

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Ho, Li-Hsing, Tien-Fu Peng, Shu-Yun Feng, and Tieh-Min Yen. "Benchmarking of standard hotel service quality by KD-IPA model." Journal of Statistics and Management Systems 14, no. 6 (November 2011): 1117–41. http://dx.doi.org/10.1080/09720510.2011.10701604.

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Du, Juan, Jiqiao Liu, Decang Bi, Xiuhua Ma, Xia Hou, Xiaolei Zhu, and Weibiao Chen. "Validation of double-pulse 1572 nm integrated path differential absorption lidar measurement of carbon dioxide." EPJ Web of Conferences 176 (2018): 01031. http://dx.doi.org/10.1051/epjconf/201817601031.

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A ground-based double-pulse 1572 nm integrated path differential absorption (IPDA) lidar was developed for carbon dioxide (CO2) column concentrations measurement. The lidar measured the CO2 concentrations continuously by receiving the scattered echo signal from a building about 1300 m away. The other two instruments of TDLAS and in-situ CO2 analyzer measured the CO2 concentrations on the same time. A CO2 concentration measurement of 430 ppm with 1.637 ppm standard error was achieved.

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Manabe, Seiji, Kiyotaka Tanikawa, and Koichi Yokoyama. "Simultaneous determination of the Earth rotation parameters and coordinates of the optical astrometric stations." Symposium - International Astronomical Union 128 (1988): 153–58. http://dx.doi.org/10.1017/s0074180900119424.

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The earth rotation parameters and coordinates of optical astrometric stations from 1962. O to 1986. O are estimated simultaneously on the assumption that the system of selected standard stations does not rotate. Longitudes and latitudes of the stations are determined every 2 months. Disagreement of the ERPs with those obtained by the space techniques decreased much compared with the published ERPs of the IPMS. It is expected that the ERPs in the whole period are also improved significantly.

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Thakur, Binay, Mukti Devkota, Di Yonghui, Yogesh Regmi, Durga Khanal, and Kopila Khadaka. "SMA first approach Pancreaticoduodenectomy for cancer – should it be standard approach?" Journal of Society of Surgeons of Nepal 18, no. 3 (July 25, 2016): 26. http://dx.doi.org/10.3126/jssn.v18i3.15289.

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Background: pancreaticoduodenectomy (PD) has become the standard treatment for cancer of head of pancrease and periampullary malignancies. Recently superior mesenteric artery (SMA) first approach has shown to have several advantages over the conventional superior mesenteric vein (SMV) first approach. We present our initial experience with SMA first approach for PD.Methods: Thirteen patients undergoing SMA first PD during year 2014-2015 (1 year) were prospectively studied. A posterior approach with “hanging maneuver” was used to identify SMA first and the resectibility was confirmed. Inferior pancreaticoduodenal artery (IPDA) was ligated before the division of pancreatic neck. Duct to mucosa pancreaticojejunostomy followed by hepaticojejunostomy and gastrojejunostomy was performed.Results: patients with mean age of 53 years presented with abdominal pain and jaundice (100%). Tumors were of periampullary region in 10 cases and of head of pancrease in three cases. Two patients required partial SMV wall resection with tangential repair. Mean operating time, blood loss and postoperative stay was 304 minutes, 380 ml and 14 days, respectively. Replaced/ aberrant right hepatic artery from SMA was observed in 38% cases. Mean number of dissected nodes was 16. R0 resection was achieved in 100% cases. There was one postoperative mortality (7.7%) and minor complications were noted in 46% cases.Conclusion: SMA first PD helps to properly identify and control anomalous or accessory right hepatic artery arising from SMA, minimizes intraoperative bleeding due to proper control.

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Samaranayake, B. G. L. T., D. M. G. Preethichandra, A. M. U. S. K. Alahakoon, and K. Kaneto. "Dynamic Modeling of Ionic Polymer Metal Composite Using Equivalent Passive Electric Network Components." Advanced Materials Research 452-453 (January 2012): 1159–63. http://dx.doi.org/10.4028/www.scientific.net/amr.452-453.1159.

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This paper presents dynamic modeling of Ionic Polymer Metal Composites (IPMC) using passive electric network components. The dynamic model using standard electric network components is a novel approach to model the transient and steady state voltage and current characteristics of IPMCs. This leads to a global model for IPMCs with fine tunable parameters, which depend on the material properties, the manufacturing process and the physical dimensions of the actuator. The dynamic model has been verified by simulation, system identification and experimental studies.

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Benedetti, Andrea, Yin Wu, Brooke Levis, Machelle Wilchesky, Jill Boruff, John P. A. Ioannidis, Scott B. Patten, et al. "Diagnostic accuracy of the Geriatric Depression Scale-30, Geriatric Depression Scale-15, Geriatric Depression Scale-5 and Geriatric Depression Scale-4 for detecting major depression: protocol for a systematic review and individual participant data meta-analysis." BMJ Open 8, no. 12 (December 2018): e026598. http://dx.doi.org/10.1136/bmjopen-2018-026598.

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IntroductionThe 30-item Geriatric Depression Scale (GDS-30) and the shorter GDS-15, GDS-5 and GDS-4 are recommended as depression screening tools for elderly individuals. Existing meta-analyses on the diagnostic accuracy of the GDS have not been able to conduct subgroup analyses, have included patients already identified as depressed who would not be screened in practice and have not accounted for possible bias due to selective reporting of results from only better-performing cut-offs in primary studies. Individual participant data meta-analysis (IPDMA), which involves a standard systematic review, then a synthesis of individual participant data, rather than summary results, could address these limitations. The objective of our IPDMA is to generate accuracy estimates to detect major depression for all possible cut-offs of each version of the GDS among studies using different reference standards, separately and among participant subgroups based on age, sex, dementia diagnosis and care settings. In addition, we will use a modelling approach to generate individual participant probabilities for major depression based on GDS scores (rather than a dichotomous cut-off) and participant characteristics (eg, sex, age, dementia status, care setting).Methods and analysisIndividual participant data comparing GDS scores to a major depression diagnosis based on a validated structured or semistructured diagnostic interview will be sought via a systematic review. Data sources will include Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO and Web of Science. Bivariate random-effects models will be used to estimate diagnostic accuracy parameters for each cut-off of the different versions of the GDS. Prespecified subgroup analyses will be conducted. Risk of bias will be assessed with the Quality Assessment of Diagnostic Accuracy Studies-2 tool.Ethics and disseminationThe findings of this study will be of interest to stakeholders involved in research, clinical practice and policy.PROSPERO registration numberCRD42018104329.

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Bassi, Antonio. "General Management Principles in the Project Management Context." International Journal of Management Science and Business Administration 2, no. 11 (2014): 14–19. http://dx.doi.org/10.18775/ijmsba.1849-5664-5419.2014.211.1002.

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In order that the projects can become the tools by which organizations can realize their strategic objectives it is necessary to define a culture of project management that involves the whole organization. This type of culture could be started through the definition of the main principles of General Management that govern the management of projects in an organizational context. This work is aimed to analyze the ISO norm 10006 “Quality Management Systems – Guidelines for quality management in projects” not by the quality point of view in a project management context but by the contribute to the growth of organizations through the definition implicit or explicit of principles on which it must base an organization that works for projects. The results of this study revealed that implicit and explicit principles of general management help to involve all parts of an organization and improve the management of organizational projects successfully. It will be also taken in comparison the most important project management standards such as ISO21500, PMBOK, IPMA, PRINCE2.

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Kayal, Maia, Michael Plietz, Anam Rizvi, Marlana Radcliffe, Alexa Riggs, Clara Yzet, Emily Tixier, et al. "Inflammatory Pouch Conditions Are Common After Ileal Pouch Anal Anastomosis in Ulcerative Colitis Patients." Inflammatory Bowel Diseases 26, no. 7 (October 6, 2019): 1079–86. http://dx.doi.org/10.1093/ibd/izz227.

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Abstract Background Total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) is the gold standard surgery for ulcerative colitis (UC) patients with medically refractory disease. The aim of this study was to report the rates and risk factors of inflammatory pouch conditions. Methods This was a retrospective review of UC or IBD unspecified (IBDU) patients who underwent TPC with IPAA for refractory disease or dysplasia between 2008 and 2017. Pouchoscopy data were used to calculate rates of inflammatory pouch conditions. Factors associated with outcomes in univariable analysis were investigated in multivariable analysis. Results Of the 621 patients more than 18 years of age who underwent TPC with IPAA between January 2008 and December 2017, pouchoscopy data were available for 386 patients during a median follow-up period of 4 years. Acute pouchitis occurred in 205 patients (53%), 60 of whom (30%) progressed to chronic pouchitis. Cuffitis and Crohn's disease–like condition (CDLC) of the pouch occurred in 119 (30%) patients and 46 (12%) patients, respectively. In multivariable analysis, female sex was associated with a decreased risk of acute pouchitis, and pre-operative steroid use and medically refractory disease were associated with an increased risk; IBDU was associated with chronic pouchitis; rectal cuff length ≥2 cm and medically refractory disease were associated with cuffitis; age 45–54 at colectomy was associated with CDLC. Rates of pouch failure were similar in chronic pouchitis and CDLC patients treated with biologics and those who were not. Conclusions Inflammatory pouch conditions are common. Biologic use for chronic pouchitis and CDLC does not impact the rate of pouch failure.

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GOLDWORTH, AMNON. "Compassionate Utilitarianism: The Unknown Bentham Revealed." Cambridge Quarterly of Healthcare Ethics 11, no. 2 (April 2002): 191–96. http://dx.doi.org/10.1017/s0963180102002128.

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Unlike the compassionate conservatism of George Bush, Compassionate Utilitarianism is not a confusing concept. Nor is it a newly minted version of Utilitarianism given that it is embedded in the writings of Jeremy Bentham, writings that have come to light only with the Oxford University Press publication of his Deontology in 1983 as edited by me. Bentham's An Introduction to the Principles of Morals and Legislation (IPML) expresses the standard interpretation of Hedonistic Utilitarianism. What he said in Deontology serves as the basis of Compassionate Utilitarianism.

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Journal articles on the topic 'Standard IPMA'

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