Academic literature on the topic 'Standard uptake value (SUV)'
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Journal articles on the topic "Standard uptake value (SUV)"
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De Jong, W. K., H. F. Van der Heijden, J. Pruim, W. J. Oyen, and H. J. Groen. "Prognostic value of different standard uptake values (SUV) of primary tumor measured with FDG-PET in resectable non-small cell lung cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7214. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7214.
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7214 Background: The SUV is a measure for the preferential uptake of a radiopharmaceutical in a tumor compared with a homogenous distribution in a body. SUV can be based on the maximum value (SUVmax) or on the mean value in a region outlined by isodensity contours, e.g., 70% and 50%. The prognostic value of the different SUVs in non-small cell lung cancer (NSCLC) is not clear. We evaluated the prognostic value of SUVmax, SUV 70% and SUV 50% in patients (pts) with resectable NSCLC. Methods: All consecutive pts who underwent an attenuation corrected whole body FDG-PET scan were selected. All data were reconstructed iteratively. Only pts with stage I through IIIA NSCLC were included. By adjusting the isocontour in the region of interest, the SUVmax, SUV 70% and SUV 50% of the primary tumor were calculated. Cox regression analysis was used to calculate the relation between the different SUVs and survival. Results: Eighty-four pts (67 males, median age 64 years, range 38–86) were included. Histology was squamous cell carcinoma (n = 43), adenocarcinoma (n = 27), large cell carcinoma (n = 13), and 1 patient with bronchoalveolar carcinoma. Nineteen pts had stage IA, 28 stage IB, 4 stage IIA, 19 stage IIB, and 14 stage IIIA. Median (range) SUVmax, SUV 70%, and SUV 50% were 6.9 (1.6–32.5), 5.5 (1.0–23.2), and 4.5 (0.9–21.9), respectively. Analysis of residuals of SUVmax as a continuous variable suggests no cut-off point and no indication of time-dependency. By univariate analysis, all pts with a SUV higher than the median value had a worse survival than pts with a SUV lower than median (Hazard ratio’s for SUVmax, SUV70% and SUV 50% were 2.3 (p = 0.024), 2.5 (p = 0.015), and 2.7 (p = 0.010), respectively). Conclusions: SUVmax, SUV 70% and SUV 50% measured with FDG-PET have a similar prognostic impact. No cut-off point for SUVmax has been observed. No significant financial relationships to disclose.
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Walker, Matthew D., Katherine Dinelle, Rick Kornelsen, et al. "[11C]PBR28 PET Imaging is Sensitive to Neuroinflammation in the Aged Rat." Journal of Cerebral Blood Flow & Metabolism 35, no. 8 (2015): 1331–38. http://dx.doi.org/10.1038/jcbfm.2015.54.
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Neuroinflammation in the aging rat brain was investigated using [11C]PBR28 microPET (positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p.G2019S transgenic rats; this mutation increases the risk of Parkinson's disease in humans. Seventy [11C]PBR28 PET scans were acquired. Arterial blood sampling enabled tracer kinetic modeling and estimation of VT. In vitro autoradiography was also performed. PBR28 uptake increased with age, without differences between nontransgenic and transgenic rats. In 12 months of aging (4 to 16 months), standard uptake value (SUV) increased by 56% from 0.44 to 0.69 g/mL, whereas VT increased by 91% from 30 to 57 mL/cm3. Standard uptake value and VT were strongly correlated (r = 0.52, 95% confidence interval (CI) = 0.31 to 0.69, n = 37). The plasma free fraction, fp, was 0.21 ± 0.03 (mean ± standard deviation, n = 53). In vitro binding increased by 19% in 16 months of aging (4 to 20 months). The SUV was less variable across rats than VT; coefficients of variation were 13% ( n = 27) and 29% ( n = 12). The intraclass correlation coefficient for SUV was 0.53, but was effectively zero for VT. These data show that [11C]PBR28 brain uptake increases with age, implying increased microglial activation in the aged brain.
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Rohani, Mohd Fazrin Mohd, Siti Nurshahirah Mohd Yonan, Nashrulhaq Tagiling, Wan Mohd Nazlee Wan Zainon, Yusri Udin, and Norazlina Mat Nawi. "Standardized Uptake Value from Semiquantitative Bone Single-Photon Emission Computed Tomography/Computed Tomography in Normal Thoracic and Lumbar Vertebrae of Breast Cancer Patients." Asian Spine Journal 14, no. 5 (2020): 629–38. http://dx.doi.org/10.31616/asj.2019.0308.
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Study DesignRetrospective study.PurposeThis study aims to semiquantitatively evaluate the standardized uptake value (SUV) of 99mTc-methylene diphosphonate (MDP) radionuclide tracer in the normal vertebrae of breast cancer patients using an integrated single-photon emission computed tomography (SPECT)/computed tomography (CT) scanner.Overview of LiteratureMolecular imaging techniques using gamma cameras and stand-alone SPECT have traditionally been utilized to evaluate metastatic bone diseases. However, these methods lack quantitative analysis capabilities, impeding accurate uptake characterization.MethodsA total of 30 randomly selected female breast cancer patients were enrolled in this study. The SUV mean (SUVmean) and SUV maximum (SUVmax) values for 286 normal vertebrae at the thoracic and lumbar levels were calculated based on the patients’ body weight (BW), body surface area (BSA), and lean body mass (LBM). Additionally, 106 degenerative joint disease (DJD) lesions of the spine were also characterized, and both their BW SUVmean and SUVmax values were obtained. A receiver operating characteristic (ROC) curve analysis was then performed to determine the cutoff value of SUV for differentiating DJD from normal vertebrae.ResultsThe mean±standard deviations for the SUVmean and SUVmax in the normal vertebrae displayed a relatively wide variability: 3.92±0.27 and 6.51±0.72 for BW, 1.05±0.07 and 1.75±0.17 for BSA, and 2.70±0.19 and 4.50±0.44 for LBM, respectively. Generally, the SUVmean had a lower coefficient of variation than the SUVmax. For DJD, the mean±standard deviation for the BW SUVmean and SUVmax was 5.26±3.24 and 7.50±4.34, respectively. Based on the ROC curve, no optimal cutoff value was found to differentiate DJD from normal vertebrae.ConclusionsIn this study, the SUV of 99mTc-MDP was successfully determined using SPECT/CT. This research provides an approach that could potentially aid in the clinical quantification of radionuclide uptake in normal vertebrae for the management of breast cancer patients.
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Luo, J. "SU-FF-I-78: Estimate Standard Uptake Value (SUV) in F18 FDG PET Tumor Imaging." Medical Physics 33, no. 6Part4 (2006): 2014–15. http://dx.doi.org/10.1118/1.2240758.
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Castellucci, P., P. S. Duarte, and A. Alavi. "DETECTION OF BONE METASTASIS WITH FDG-PET USING STANDARD UPTAKE VALUE (SUV) AND VISUAL ANALYSIS." Clinical Nuclear Medicine 24, no. 6 (1999): 469. http://dx.doi.org/10.1097/00003072-199906000-00032.
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Poyraz, Necdet, Cihan Şimşek, Celalettin Korkmaz, and Buğra Kaya. "Functional imaging in non-small cell lung carcinoma: Correlation between standardized uptake values and apparent diffusion coefficient values." International Journal Of Medical Science And Clinical Invention 5, no. 4 (2018): 3721–26. http://dx.doi.org/10.18535/ijmsci/v5i4.01.
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Objective: To investigate the relationship between apparent diffusion coefficient (ADC) values and standard uptake value (SUV) in patients with non-small cell lung cancer (NSCLC).
 Methods: PET/CT and diffusion-weighted magnetic resonance imaging (DW MRI) were performed in 73 consecutive patients with histologically verified NSCLC. Analysing the PET/CT data calculation of the maximum and mean SUV was performed. The mean and minimum ADC values were measured directly on the parametric ADC maps.
 Results: Significant inverse correlations were found between ADCmean and SUVmean (r = - 0.53; p < 0.001) as well as ADCmin and SUVmax (r = - 0.71; p < 0.001).
 Conclusions: The significant negative correlations between ADC and SUV suggest an association between tumor cellularity and metabolic activity in NSCLC.
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Groot Jebbink, Erik, Leo H. van Den Ham, Beau B. J. van Woudenberg, et al. "Physiological Appearance of Hybrid FDG–Positron Emission Tomography/Computed Tomography Imaging Following Uncomplicated Endovascular Aneurysm Sealing Using the Nellix Endoprosthesis." Journal of Endovascular Therapy 27, no. 3 (2020): 509–15. http://dx.doi.org/10.1177/1526602820913888.
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Purpose: To investigate the physiological uptake of hybrid fluorine-18-fluorodeoxyglucose (FDG)–positron emission tomography/computed tomography (PET/CT) before and after an uncomplicated endovascular aneurysm sealing (EVAS) procedure as a possible tool to diagnose EVAS graft infection and differentiate from postimplantation syndrome. Materials and Methods: Eight consecutive male patients (median age 78 years) scheduled for elective EVAS were included in the prospective study ( ClinicalTrials.gov identifier NCT02349100). FDG-PET/CT scans were performed in all patients before the procedure and 6 weeks after EVAS. The abdominal aorta was analyzed in 4 regions: suprarenal, infrarenal neck, aneurysm sac, and iliac. The following parameters were obtained for each region: standard uptake value (SUV), tissue to background ratio (TBR), and visual examination of FDG uptake to ascertain its distribution. Demographic data were obtained from medical files and scored based on reporting standards. Results: Visual examination showed no difference between pre- and postprocedure FDG uptake, which was homogenous. In the suprarenal region no significant pre- and postprocedure differences were observed for the SUV and TBR parameters. The infrarenal neck region showed a significant decrease in the SUV and no significant decrease in the TBR. The aneurysm sac and iliac regions both showed a significant decrease in SUV and TBR between the pre- and postprocedure scans. Conclusion: Physiological FDG uptake after EVAS was stable or decreased with regard to the preprocedure measurements. Future research is needed to assess the applicability and cutoff values of FDG-PET/CT scanning to detect endograft infection after EVAS.
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Deng, Shengming, Zhifang Wu, Yiwei Wu, et al. "Meta-Analysis of the Correlation between Apparent Diffusion Coefficient and Standardized Uptake Value in Malignant Disease." Contrast Media & Molecular Imaging 2017 (2017): 1–16. http://dx.doi.org/10.1155/2017/4729547.
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The objective of this meta-analysis is to explore the correlation between the apparent diffusion coefficient (ADC) on diffusion-weighted MR and the standard uptake value (SUV) of 18F-FDG on PET/CT in patients with cancer. Databases such as PubMed (MEDLINE included), EMBASE, and Cochrane Database of Systematic Review were searched for relevant original articles that explored the correlation between SUV and ADC in English. After applying Fisher’s r-to-z transformation, correlation coefficient (r) values were extracted from each study and 95% confidence intervals (CIs) were calculated. Sensitivity and subgroup analyses based on tumor type were performed to investigate the potential heterogeneity. Forty-nine studies were eligible for the meta-analysis, comprising 1927 patients. Pooled r for all studies was −0.35 (95% CI: −0.42–0.28) and exhibited a notable heterogeneity (I2 = 78.4%; P < 0.01). In terms of the cancer type subgroup analysis, combined correlation coefficients of ADC/SUV range from −0.12 (lymphoma, n = 5) to −0.59 (pancreatic cancer, n = 2). We concluded that there is an average negative correlation between ADC and SUV in patients with cancer. Higher correlations were found in the brain tumor, cervix carcinoma, and pancreas cancer. However, a larger, prospective study is warranted to validate these findings in different cancer types.
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Favier, L., A. Berriolo-Riedinger, B. Coudert, et al. "Predicative value of [18F]-FDG PET scan for pathological complete response to neoadjuvant chemotherapy in breast cancer." Journal of Clinical Oncology 25, no. 18_suppl (2007): 505. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.505.
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505 Background: To evaluate, in breast cancer patients treated by neoadjuvant chemotherapy, the early predictive value of the FDG uptake decrease for the assessment of the pathological complete response (pCR). Methods: Forty seven women with non metastatic with conventional imaging, non inflammatory, large or locally advanced breast cancer were included. Pathological tumour regression determined on surgical resection specimens served as the gold standard for the assessment of the neoadjuvant chemotherapy response. According to the Sataloff classification, patients were classified in two groups: patients with a pathological complete response (pCR) and patients with a pathological non complete response (non pCR). FDG uptake of breast lesions was evaluated before and after the first course of neoadjuvant chemotherapy, using Standard Uptake Value maximum (SUV) corrected by body surface area and glycaemia. Relations between baseline [18F]-FDG uptake and clinical, histopathological and biological parameters were assessed by Mann-Whitney test. Predictive value of the FDG decrease for the assessment of the pCR was studied with logistic regression analysis. Results: An elevated baseline SUV was found independently associated with a high mitotic activity (p<0.002), tumour grading (p<0.004), high score of nuclear pleomorphism (p= 0.03) and positive hormonal receptor status (p<0.005). After completion of chemotherapy, 11 (23%) of the 47 breast tumours examined at surgery showed a pCR while 36 (77%) showed a non pCR. The relative decrease (ΔSUV) after the first course of neoadjuvant chemotherapy was significantly greater in the pCR group than in the non pCR group (p< 10-4). A SUV decrease of 85.4% ± 21.9% in pCR patients versus 22.6% ± 36.6% in non pCR patients was found. ΔSUV<-60% predicted pCR with an accuracy of 87%. With multivariate logistic regression analyses, ΔSUV<-60% was the only predictive factor of the pCR Conclusions: In breast cancer patients treated by neoadjuvant chemotherapy, the FDG uptake decrease, after only one course of treatment, is an early and powerful predictor of the pCR. No significant financial relationships to disclose.
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Lerman, Hedva, Shikma Bar-On, Limor Helpman, Einat Even-Sapir, and Dan Grisaru. "ATL." International Journal of Gynecologic Cancer 22, no. 7 (2012): 1187–91. http://dx.doi.org/10.1097/igc.0b013e31825bedc7.
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ObjectivePositron emission tomography/computed tomography (PET/CT) is an important tool in oncology for assessment of disease extent and recurrence. Recognition of benign fluorodeoxyglucose (FDG) uptake promotes correct interpretation of imaging data. This study assesses the appearance of benign uterine leiomyomas (ULs) on PET/CT and evaluates possible hormonal influences.Patients and MethodsThis was a retrospective study performed in a tertiary referral cancer center in Israel. One hundred fifty-two women with nongynecologic malignancies were referred for PET/CT scans, with incidental UL on imaging. Information on menopausal status and menstrual phase and on the use of oral contraceptives, hormone replacement therapy, and selective estrogen receptor modulators (SERM) was collected. Fluorodeoxyglucose uptake measured as standard uptake value (SUV) was obtained for UL, normal myometrium, and gluteus muscle. Changes associated with menopausal status, menstrual cycle phase, and the use of oral contraceptives, hormone replacement therapy, and SERM were assessed.ResultsThe mean ± SD SUV in UL for the entire cohort was 1.39 ± 0.65 and was higher than in myometrium (1.24 ± 0.33) and gluteus muscle (0.48 ± 0.36). Fluorodeoxyglucose uptake was similar in UL and in myometrium during the preovulatory (1.42 ± 0.31 vs 1.23 ± 0.34) and postovulatory (1.23 ± 0.34 vs1.38 ± 0. 4) periods. During ovulation, SUV was significantly higher in UL (1.62 ± 0.39) than in normal myometrium (1.12 ± 0.15; P = 0.01). Uterine leiomyoma FDG uptake in premenopausal women (1.47 ± 0.32) was higher than in postmenopausal women (1.29 ± 0.41; P < 0.02). The UL/gluteus SUV ratio in patients on hormone replacement therapy (2.53 ± 0.23) was significantly higher than in untreated patients (1.27 ± 0.92; P = 0.05). Lower uptake was recorded in patients on SERM (SUV, 1.1 ± 0.24) than in untreated patients (SUV, 1.41 ± 0.36; P < 0.01).ConclusionFluorine 18 FDG uptake in UL may be estrogen dependent. Endogenous estrogen and hormone replacement therapy increase FDG uptake, whereas withdrawal of estrogen by menopause or SERM decreases uptake.
Dissertations / Theses on the topic "Standard uptake value (SUV)"
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Watanabe, Masao. "Performance Evaluation of a Newly Developed MR-Compatible Mobile PET Scanner with Two Detector Layouts." Kyoto University, 2020. http://hdl.handle.net/2433/253141.
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Berdichevski, Eduardo Herz. "Impacto do contraste no c?lculo do standardized uptake value (SUV) em fun??o do tamanho da les?o e dist?ncia de ?reas de maior concentra??o de contraste." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2017. http://tede2.pucrs.br/tede2/handle/tede/7363.
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Previous issue date: 2017-01-20<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES<br>It has been shown that the use of contrast media in PET/CT (positron emission tomography/ computed tomography) studies is beneficial when compared to an unenhanced CT scan. This is due to the fact that contrast media generates better contrast regarding adjacent structures, allows better characterization of abnormalities, and also allows visualizing alterations that do not present abnormal metabolic behavior. However, contrast agents generate more absorption of CT photons in relation to those of PET potentially giving rise to errors in attenuation correction of PET images. Errors converting the attenuation map from the CT to the PET scan may lead to inaccurate quantification of PET images. The occurrence of SUV (Standardized uptake value) modifications in lesions when PET images are corrected with either contrast-enhanced or unenhanced CT scans has already been studied. Our goal, however, was to study the occurrence of such alterations in relation with lesion size, and distance from the lesion to areas of high contrast concentration, such as high caliber vases and focal areas of the gastrointestinal tract (GIT). Methods: We obtained the SUVmax of 149 lesions, from 26 patients who underwent a PET/CT scan in which images were corrected using both an unenhanced computed tomography (PETCTUE) and a contrast-enhanced computed tomography (PETCTCE). In addition, we measured lesion sizes (smallest and largest diameter, and area) and their distance to large vessels and the GIT. Size measures were not taken when the lesion could not be visualized in the CT image. For lesions in which the distance to high contrast concentration areas was too large or too small, and could not be accurately estimated, the median distance of similar lesions was used to replace the measures. Following the repeated measures principle, we obtained Lin's concordance correlation coefficient and its confidence interval. A Bland-Altman analysis was performed using the absolute difference values and ratio, between PETCTCE and PETCTUE with concordance limits. Results: A total of 149 lesions could be visualized in PET. Eleven of them could not be identified in the CT, and so their measurements were not taken. For 16 lesions, the distance to high contrast concentration areas could not be obtained. The concordance level between the methods, by Lin's concordance correlation coefficient, was 0.99 (CCC: 0.99), and the confidence interval was 95% of 0.98 ? 0.99 (IC95%: 0.98 ? 0.99). The mean absolute difference between the methods was approximately zero and the relative difference was +3.37% (concordance limits of 95% between -2.72 and +2.72, and between -15.73 and +22.48%, respectively). Eighty-two lesions had their larger diameter below 17mm and the other 56 had a larger diameter above or equal to 17mm, with mean percent variation of SUVmax from PETCTCE to PECCTUE of 3.85% and 2.83%, respectively (p=0.54). Sixty-six lesions had a smaller diameter below 17mm and the remaining 72 had a smaller diameter equal to or above 17mm. The mean percent SUVmax variation from PETCTCE to PECCTUE was 2.71%?1,74 and 3.80% ?1,60, respectively (p=0.41). Eighty-two lesions had an area larger than 2.27 cm2 and the other 57 had an area equal to or larger than 2.27 cm2. The mean percent variation of the SUVmax obtained for PETCTCE and PETCTUE was 2.81%?1.64 e 3,83%?1.70, respectively (p=0.48). Sixty-seven lesions were more than 1.82 cm distant from large vessels/ GIT, and 82 were at a less than 1cm distance. The mean SUVmax variation between the methods (PETCTCE versus PETCTUE) was 0.57?1.65% e 4.98?1.61% respectively (p < 0.005). Conclusions: For the totality of studied lesions (149), as well as for the analysis regarding the factors size (non significant p) and distance (significant p), the medium SUVmax variation we identified it not clinically relevant. Thus, both contrast-enhanced and unenhanced PET/CT can be used for attenuation correction.<br>Nos estudos de PET/CT (tomografia por emiss?o de p?sitrons/ tomografia computadorizada), o uso de material contrastado endovenoso na CT mostra benef?cios diagn?sticos em rela??o a CT n?o contrastada. Isto ocorre pois o material contrastado al?m de gerar maior contraste entre as les?es em rela??o ?s estruturas adjacentes, e melhor caracterizar as anormalidades, tamb?m permite a visualiza??o de altera??es que n?o demonstram comportamento metab?lico anormal. Entretanto, os meios de contraste geram maior absor??o dos f?tons da CT em rela??o aos do PET, e isto tende a gerar erros na corre??o de atenua??o das imagens do PET. Esses erros na convers?o do mapa de atenua??o da CT para o do PET podem levar a inacur?cias na quantifica??o das imagens do PET. A ocorr?ncia de altera??es do SUV das les?es entre as imagens de PET corrigidas para atenua??o com o CT sem contraste e com o CT contrastado j? foi amplamente estudada. Nosso objetivo foi estudar essa ocorr?ncia em fun??o do tamanho das les?es e das dist?ncias entre elas e zonas de maior concentra??o de contraste, como ? o caso de vasos calibrosos e ?reas focais em trato gastrintestinal (TGI). M?todos: Mensuramos o SUVmax de 149 les?es em 26 pacientes cujos exames de PET/CT foram corrigidos tanto utilizando tomografia n?o-contrastada (PETCTSC) quanto tomografia contrastada (PETCTCC). Al?m disso, medimos as dimens?es das les?es (maior e menor di?metro e ?rea) e suas dist?ncias para vasos calibrosos e TGI. Medidas de tamanho n?o foram feitas quando n?o foram visualizadas na CT. Em les?es cujas dist?ncias de ?reas de maior contraste n?o puderam ser feitas com seguran?a por serem muito pr?ximas ou muito grandes, suas medidas foram repostas pela mediana de les?es similares quanto a este aspecto. Seguindo o princ?pio de medidas repetidas, obteve-se o n?vel de concord?ncia dos m?todos atrav?s do coeficiente de correla??o de concord?ncia de Lin e seu respectivo intervalo de confian?a. Realizou-se uma an?lise de Bland-Altman cruzando os valores de diferen?a absoluta e de raz?o entre o PETCTCC versus o PETCTSC com os limites de concord?ncia. Resultados: Das 149 les?es visualiz?veis no PET, 11 n?o demonstraram correspond?ncia na CT, n?o sendo mensuradas suas dimens?es. Dezesseis les?es n?o tiveram calculadas as suas dist?ncias para alguma ?rea de maior concentra??o de contraste e seus valores foram repostos. O n?vel de concord?ncia dos m?todos, pelo coeficiente de correla??o de concord?ncia de Lin, foi de 0.99 (CCC: 0.99) com intervalo de confian?a de 95% de 0.98 ? 0.99 (IC95%: 0.98 ? 0.99). A diferen?a m?dia absoluta entre os m?todos foi de aproximadamente zero e relativa de +3.37% (limites de concord?ncia de 95% entre -2.72 e +2.72 e entre -15.73 e +22.48% respectivamente). Oitenta e duas les?es apresentaram maior di?metro abaixo de 17mm e as outras 56, igual ou acima de 17mm, com diferen?a m?dia percentual dos SUVmax medida nos PETCTCC e PETCTSC igual a 3,85%?1,65 e 2,83%?1,80 respectivamente (p = 0,54). Sessenta e seis les?es apresentaram menor di?metro abaixo do que 17mm e as demais 72, di?metro igual ou acima de 17mm. A diferen?a m?dia percentual dos SUVmax medida nos PETCTCC e PETCTSC foi igual a 2,71%?1,74 e 3,80% ?1,60 respectivamente (p = 0,41). Oitenta e uma les?es apresentaram ?rea menor que 2,27 cm2 e as outras 57, ?rea igual ou maior que 2,27 cm2. A diferen?a m?dia percentual dos SUVmax medida nos PETCTCC e PETCTSC foi igual a 2,81%?1,64 e 3,83%?1,70 respectivamente (p = 0,48). Sessenta e sete les?es tinham dist?ncia de vasos calibrosos/ TGI acima de 1cm, e 82, igual ou menor que 1cm. A diferen?a m?dia percentual entre os m?todos (PETCTCC versus PETCTSC) foi igual a 0,57?1,65% e 4,98?1,61% respectivamente (p < 0,005). Conclus?es: Mesmo para o grupo total de les?es (149) bem como para os grupos de les?es separados em fun??o dos fatores ?tamanho? (p n?o significativo) e ?dist?ncia? (p significativo), a varia??o m?dia do SUVmax visualizada n?o tem relev?ncia cl?nica, tornando intercambi?vel a corre??o do PET pelo CT sem e com contraste.
Books on the topic "Standard uptake value (SUV)"
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Sun, Huatong. Global Social Media Design. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190845582.001.0001.
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Social media users fracture into tribes, but social media ecosystems are globally interconnected technically, socially, culturally, and economically. At the crossroads, Huatong Sun, author of Cross-Cultural Technology Design, presents theory, method, and case studies to uncover the global interconnectedness of social media design and reorient universal design standards. Centering on the dynamics between structure and agency, Sun draws on practices theories and transnational fieldwork and articulates a critical design approach. The culturally localized user engagement and empowerment (CLUE<sup>2</sup>, or CLUE-squared) framework extends from situated activity to social practice and connects macro institutions with micro interactions to redress asymmetrical relations in everyday life. Why were Japanese users not crazed about Facebook? Would Twitter have been more successful than its copycat Weibo in China if not banned? How did mobilities and value propositions play out in the competition of WhatsApp, WeChat, LINE, and KakaoTalk for global growth? Illustrating the cultural entanglement with a relational view of design, Sun provides three provocative accounts of cross-cultural social media design and use. Concepts such as affordance, genre, and uptake are demonstrated as design tools to bind the material with the discursive and leap from the critical to the generative for culturally sustaining design. Sun calls to reshape the crossroads into a design square where differences are nourished as design resources, where diverse discourses interact for innovation, and where alternative design epistemes thrive from the local. This timely book will appeal to researchers, students, and practitioners who design across disciplines, paradigms, and boundaries to bridge differences in this increasingly globalized world.
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Trepulė, Elena, Airina Volungevičienė, Margarita Teresevičienė, et al. Guidelines for open and online learning assessment and recognition with reference to the National and European qualification framework: micro-credentials as a proposal for tuning and transparency. Vytauto Didžiojo universitetas, 2021. http://dx.doi.org/10.7220/9786094674792.
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These Guidelines are one of the results of the four-year research project “Open Online Learning for Digital and Networked Society” (2017-2021). The project objective was to enable university teachers to design open and online learning through open and online learning curriculum and environment applying learning analytics as a metacognitive tool and creating open and online learning assessment and recognition practices, responding to the needs of digital and networked society. The research of the project resulted in 10 scientific publications and 2 studies prepared by Vytautas Magnus university Institute of Innovative Studies research team in collaboration with their international research partners from Germany, Spain and Portugal. The final stage of the research attempted creating open and online learning assessment and recognition practices, responding to the learner needs in contemporary digital and networked society. The need for open learning recognition has been increasing during the recent decade while the developments of open learning related to the Covid 19 pandemics have dramatically increased the need for systematic and high-quality assessment and recognition of learning acquired online. The given time also relates to the increased need to offer micro-credentials to learners, as well as a rising need for universities to prepare for micro-credentialization and issue new digital credentials to learners who are regular students, as well as adult learners joining for single courses. The increased need of all labour - market participants for frequent and fast renewal of competences requires a well working and easy to use system of open learning assessment and recognition. For learners, it is critical that the micro-credentials are well linked to national and European qualification frameworks, as well as European digital credential infrastructures (e.g., Europass and similar). For employers, it is important to receive requested quality information that is encrypted in the metadata of the credential. While for universities, there is the need to properly prepare institutional digital infrastructure, organizational procedures, descriptions of open learning opportunities and virtual learning environments to share, import and export the meta-data easily and seamlessly through European Digital Hub service infrastructures, as well as ensure that academic and administrative staff has digital competencies to design, issue and recognise open learning through digital and micro-credentials. The first chapter of the Guidelines provides a background view of the European Qualification Framework and National Qualification frameworks for the further system of gaining, stacking and modelling further qualifications through open online learning. The second chapter suggests the review of current European policy papers and consultations on the establishment of micro-credentials in European higher education. The findings of the report of micro-credentials higher education consultation group “European Approach to Micro-credentials” is shortly introduced, as well as important policy discussions taking place. Responding to the Rome Bologna Comunique 2020, where the ministers responsible for higher education agreed to support lifelong learning through issuing micro-credentials, a joint endeavour of DG Employment, Social Affairs and Inclusion and DG Research and Innovation resulted in one of the most important political documents highlighting the potential of micro-credentials towards economic, social and education innovations. The consultation group of experts from the Member States defined the approach to micro-credentials to facilitate their validation, recognition and portability, as well as to foster a larger uptake to support individual learning in any subject area and at any stage of life or career. The Consultation Group also suggested further urgent topics to be discussed, including the storage, data exchange, portability, and data standards of micro-credentials and proposed EU Standard of constitutive elements of micro-credentials. The third chapter is devoted to the institutional readiness to issue and to recognize digital and micro-credentials. Universities need strategic decisions and procedures ready to be enacted for assessment of open learning and issuing micro-credentials. The administrative and academic staff needs to be aware and confident to follow these procedures while keeping the quality assurance procedures in place, as well. The process needs to include increasing teacher awareness in the processes of open learning assessment and the role of micro-credentials for the competitiveness of lifelong learners in general. When the strategic documents and procedures to assess open learning are in place and the staff is ready and well aware of the processes, the description of the courses and the virtual learning environment needs to be prepared to provide the necessary metadata for the assessment of open learning and issuing of micro-credentials. Different innovation-driven projects offer solutions: OEPass developed a pilot Learning Passport, based on European Diploma Supplement, MicroHE developed a portal Credentify for displaying, verifying and sharing micro-credential data. Credentify platform is using Blockchain technology and is developed to comply with European Qualifications Framework. Institutions, willing to join Credentify platform, should make strategic discussions to apply micro-credential metadata standards. The ECCOE project building on outcomes of OEPass and MicroHE offers an all-encompassing set of quality descriptors for credentials and the descriptions of learning opportunities in higher education. The third chapter also describes the requirements for university structures to interact with the Europass digital credentials infrastructure. In 2020, European Commission launched a new Europass platform with Digital Credential Infrastructure in place. Higher education institutions issuing micro-credentials linked to Europass digital credentials infrastructure may offer added value for the learners and can increase reliability and fraud-resistant information for the employers. However, before using Europass Digital Credentials, universities should fulfil the necessary preconditions that include obtaining a qualified electronic seal, installing additional software and preparing the necessary data templates. Moreover, the virtual learning environment needs to be prepared to export learning outcomes to a digital credential, maintaining and securing learner authentication. Open learning opportunity descriptions also need to be adjusted to transfer and match information for the credential meta-data. The Fourth chapter illustrates how digital badges as a type of micro-credentials in open online learning assessment may be used in higher education to create added value for the learners and employers. An adequately provided metadata allows using digital badges as a valuable tool for recognition in all learning settings, including formal, non-formal and informal.
Book chapters on the topic "Standard uptake value (SUV)"
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Herzog, H., and R. D. Hichwa. "Image reconstruction, quantification and standard uptake value." In PET in Clinical Oncology. Steinkopff, 2000. http://dx.doi.org/10.1007/978-3-642-57703-1_3.
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Szopa, I., K. Gorczewski, A. d’Amico, and B. Jarząb. "Is there a necessity of Standard Uptake Value correction in liver reference level?" In IFMBE Proceedings. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03879-2_176.
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Maxwell, Rachel, and Roshni Khatri. "Exploring Active Blended Learning Through the Lens of Team-Based Learning." In Cases on Active Blended Learning in Higher Education. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-7856-8.ch009.
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This chapter showcases how the collaborative learning and teaching strategy known as Team-Based Learning™ (TBL) can deliver against the conceptual components within active blended learning (ABL), through exploration of different case studies from the authors' university. It begins by detailing the core concepts and theories underpinning each pedagogic approach before considering how adoption of TBL is consistent with the wider implementation of ABL. Case histories are used to highlight how these approaches enhance the student learning experience and how learning technologies can enable staff to do more of what they value within the classroom. The value of different learning spaces to facilitate TBL and augment the learning experience for both staff and students is considered. Finally, the chapter explores some of the more difficult questions around the lack of broader uptake of TBL within an institution committed to ABL as its standard approach to learning and teaching.
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Olatunji, Oluwole Alfred, and William David Sher. "A Comparative Analysis of 2D Computer-Aided Estimating (CAE) and BIM Estimating Procedures." In Handbook of Research on Building Information Modeling and Construction Informatics. IGI Global, 2010. http://dx.doi.org/10.4018/978-1-60566-928-1.ch008.
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Most estimators are trained with, and are used to, manual and Computer-Aided Design and Drafting (CADD) two dimensional (2D) drawings. The spatio-temporal limitations of these designs complicate information management, estimators’ judgments, speed and accuracy. In addition, conventional estimating practices also need to cater to the nuances of diverse standard methods of measurements (SMM) and unstable market conditions. Building Information Modeling (BIM) promises major improvements that overcome the limitations of conventional 2D methods in both design and construction processes. It provides platforms for value integration, robust information sources, simultaneous access to design database, automated quantification, project visualization and simulation, among others capabilities. These capabilities facilitate accuracy, objective risk assessment, comprehensive information management and early integration of cost management principles during design. Arguably, the uptake of Information Technology (IT) in construction is increasing and this discipline-specific study on BIM highlights its considerable potential for improving professional service delivery. Consequently, the integration of BIM and process driven Computer-Aided Estimating (CAE) tools and applications provide robust opportunities for process improvement in Architectural, Engineering, Construction and Facilities Management (AECFM) industries. As part of a research initiative, this chapter reviews the impacts of BIM on cost estimating procedures. In a bid to develop a conceptual framework for underpinning BIM-propelled changes in estimating practice, CAE applications are categorized and compared. Moreover, some features for producing automated quantities from BIMs are compared with provisions of SMM used by estimators. The research concludes with recommendations about the capacity of BIM to revolutionize construction procurement and systems.
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Mitchell, Alex J. "Overview of Depression Scales and Tools." In Screening for Depression in Clinical Practice. Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780195380194.003.0005.
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There have been a large number of depression tools published for the purposes of detecting depression or rating its severity. Choosing between them is difficult without adequate information on their validity, reliability, and acceptability. Recently, ever-shorter-version mood measures have been released. Is a shorter scale a better scale? It is important to study each method against our best standard and ideally compare scales head to head to judge the optimal scale for each situation. Clinicians and researchers have developed a bewildering number of tools for the assessment of depression. These are most often questionnaires designed to help elicit symptoms of depression for the purpose of screening, diagnosis, and monitoring progress (Textbox 2.1). Although we often use the terms screening, diagnosis, and case-finding interchangeably, in an epidemiologic sense screening refers to the attempted detection of disorder in those who had not sought testing or did not suspect they had a particular condition. Often a screening test is not usually intended to be diagnostic, in that those with suspicious findings may be referred for more definitive examination. The latter is perhaps better known as case-finding. This means a screening tool can favor negative predictive value (NPV) over positive predictive value (PPV) (see Chapter 5). In both screening and case-finding the test may be applied ‘‘routinely’’ to all cases, or selectively to those thought to be at high risk. A screening test applied to many individuals should be as simple as possible to retain high uptake, and positive results must be paired with an acceptable next step. A case-finding measure may be more involved but should still consider acceptability. Adoption of a test in clinical practice probably depends more on acceptability than accuracy. During the past five decades there has been a considerable effort to improve the methods used to detect and quantify depression (Textbox 2.2). Some scales, such as theCronholm-Ottosson Depression Scale, have fallen into obscurity,while others, such as the Hamilton Depression Rating Scale and the Beck Depression Inventory, have each been cited over 10,000 times. Given that there are so many similar depression scales, it is not surprising that clinicians have trouble choosing between them.
Conference papers on the topic "Standard uptake value (SUV)"
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Steinacker, J., S. Schmidt, V. Prasad, AJ Beer, A. Wienke та A. Surov. "Metaanalysis of associations between FDG uptake measured as standardized uptake value (SUV) and HIF-1α expression in solid tumors". У NuklearMedizin 2020. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1708330.
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Hara, Takeshi, Tatsunori Kobayashi, Kazunao Kawai, et al. "Automated scoring system of standard uptake value for torso FDG-PET images." In Medical Imaging, edited by Maryellen L. Giger and Nico Karssemeijer. SPIE, 2008. http://dx.doi.org/10.1117/12.770456.
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Shostak, Eugene, Alla V. Tibbetts, Jennifer B. Midle, and David R. Riker. "The Use Of Positron Emission Tomography (PET) Standardized Uptake Value (SUV) To Determine Prognosis In Non-Small Cell Lung Cancer (NSCLC)." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5140.
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Gong, Qiuming, Yaoyu Li, and Zhong-Ren Peng. "Optimal Power Management of Plug-In Hybrid Electric Vehicles With Trip Modeling." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-41638.
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Hybrid electric vehicles (HEV) have demonstrated their capability of improving the fuel economy and emission. The Plug-in HEV (PHEV), utilizing more battery power, has become a more attractive upgrade of HEV. The charge-depletion mode is more appropriate for the power management of PHEV, i.e. the state of charge (SOC) is expected to drop to a low threshold when the vehicle reaches the destination of the trip. In the past, the trip information has been considered as future information for vehicle operation and thus unavailable a priori. This situation can be changed by the current advancement of Intelligent Transportation Systems (ITS) based on the use of on-board GPS, GIS and advanced traffic flow modeling techniques. In this paper, a new approach of optimal power management of PHEV in the charge-depletion mode is proposed with driving cycle modeling based on the historic traffic information for the highway portion and the traffic lights signals information for the local road portion. A dynamic programming (DP) algorithm is applied to reinforce the charge-depletion control such that the SOC drops to a specific terminal value at the final time of the cycle. The vehicle model was based on a hybrid SUV. Only fuel consumption is considered for the current stage of study. For the local road part, a trip modeling scheme was developed based on the synchronization with the traffic signals. Simulation study was conducted for several standard driving cycles, and then for an example trip. The results showed significant improvement in fuel economy compared with a rule-based control and a depletionsustenance control for most cases. The benefit of using traffic signal in trip modeling was also revealed from the improved fuel economy.
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Almeida, Giana, and Patrick Perre. "Non-Fickian diffusion in biomaterials." In 21st International Drying Symposium. Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7943.
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The knowledge of water vapour diffusion in materials is very important in several fields of application (drying, building materials, biofilms…). Regarding the drying process, the value of mass diffusivity, as well as its variations with moisture content, governs the second drying period, which is the most important in terms of drying time, energy consumption and product quality. In the case of biomaterials used for building insulation, this parameter is essential for transformation processes, including drying, but also for the proper design and use of buildings. Concerning biofilms, barrier properties are one of the most important physical properties of these materials to properly ensure a good end use. Nevertheless, experimental data of mass uptake of some biomaterials showed that did not follow the standard Fickian model. The precise determination of this non-Fickian behaviour showed to be a difficult task since the physical phenomena responsible for such behaviours depend on the biomaterial structure and physical properties. In particular, the abnormal macroscopic behaviour could result from the pore morphology (dual-scale effects), from the nano-structure, from the molecular reorganisation, or a combination of these spatial scales. This conference proposes a new methodology to quantify the non-Fickian diffusion. Based on a macroscopic formulation of coupled heat and mass transfer with kernel functions, the model parameters, intrinsic characteristic of the product of interest are determined by inverse analysis. Several complementary transient experiments can be analysed simultaneously, which insures the method robustness. Application examples are proposed for different products, including lignocellulosic materials and nanostructured biofilms.
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Suhas, K. R. "Audit on the role and efficacy of PET/CT in recurrent ovarian cancer settings in a tertiary care centre in India." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685301.
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Ovarian cancers tend to recur in 15-70% cases. CA-125 - is a tumor marker used for monitoring therapeutic response, and in surveillance, for recurrent disease. However, it has a limited role as a persistent high level can signify either recurrence or persistence of residual tumor. Metastases from ovarian cancer primarily involve the peritoneum rather than parenchymal sites; thus, the presence of small-volume recurrence or metastatic deposits on the visceral surfaces poses a challenge for interpretation of CT and MR images. PET/CT utilizes its property of higher accumulation in malignant cells to provide both anatomic and functional information for diagnosing malignant tumors. Objectives: The objectives of the study were to find the correlation between PET/CT findings and final histopathological diagnosis after a secondary cytoreductive surgery in suspected ovarian cancer recurrences. Materials and Methods: PET/CT was done in cases with rising or above normal CA-125 and no radiological findings. These patients with abnormal PET/CT findings were taken up for a secondary cytoreductive surgery and histopathological proven were taken as the standard against which PET/CT positive findings was compared. Results: The mean age in our group of patients with suspected recurrence was 53 years (Range 39-74 years). Of the 52 patients with suspected recurrence, 40 patietnts with a PET-CT scan with findings suggestive of an avid uptake underwent surgery. 22 patients had serous histology, 12 mucinous and 8 had clear cell carcinoma. Stage-wise distribution at the time of primary surgery is as follows stage I-3, stage II-7, stage III-26, stage IV-4. Of the 40 patients who underwent a second look surgery 32 had histopathologically confirmed recurrence. PET-CT detected a total of 86 lesions in the 40 patients who underwent surgery. Of these, 38 were in the lymph nodes 28 in para-aortic and 10 in pelvic, 32 were peritoneal lesions and 14 were pelvic, 2 were metastatic in the parenchyma of liver. Detection of the lesion on PET-CT was size dependant, of the 9 lesions were missed on PET-CT, 7 were less than 0.5 cm. The mean diameter of the lesions detected was 2.2 cm (range 0.3-6.2 cm). PET-CT accurately identified 62 of 70 histopathologically proven lesions. The overall lesion-based sensitivity of PET-CT is 88.6%, specificity 56.2%, Positive predictive value being 72.1%, negative predictive value of 69.2%. Accuracy of detecting lesions greater than 1 cm is 78.6% (44 of 56 lesions). Conclusions: Corelation between PET/CT and histopathologicaldisease: k (cohen value) = 0.81 which suggests excellent correlation. For selected patients with ovarian cancer recurrence may benefit from a comprehensive radiographic imaging survey (PET-CT) at the time of even no or minimal CA-125 elevation in early detection and successful cytoreductive surgical resection and an increase in overall survival.