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Journal articles on the topic 'Staphylococcus aureus. Drug resistance in microorganisms. Molecular epidemiology'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Souza, Geziella Áurea Aparecida Damasceno, Anna Christina de Almeida, Mauro Aparecido de Sousa Xavier, et al. "Characterization and molecular epidemiology of Staphylococcus aureus strains resistant to beta-lactams isolated from the milk of cows diagnosed with subclinical mastitis." December-2019 12, no. 12 (2019): 1931–39. http://dx.doi.org/10.14202/vetworld.2019.1931-1939.

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Background and Aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp., which is extremely virulent and multidrug-resistant. Although the term is used to designate nosocomial pathogens, in a milking environment, strains of Methicillin-resistant S. aureus have been isolated from cattle diagnosed with clinical and subclinical mastitis. Resistant strains may be involved in the transfer of genes conferring resistance to beta-la

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Da Costa, Thaina Miranda, Valéria Vieira, and Fábio Aguiar Alves. "Update on major clones of methicillin-resistant Staphylococcus aureus colonizing and/or infecting humans and its distribution in Brazil." Cadernos UniFOA 7, no. 19 (2017): 93. http://dx.doi.org/10.47385/cadunifoa.v7i19.1106.

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Staphylococcus aureus is a bacterium well known for its ability to acquire genes for resistance to antimicrobial drugs. A few years after the discovery of penicillin, which initiated the era of antibiotics, resistance to this drug had already been reported in hospitals and in a few decades also became a problem within the communities. Likewise, shortly after the introduction of methicillin as a therapeutic option, the resistance was observed. The indiscriminate use of antibiotics is an important factor contributing to the emergence of new resistant strains. This pathogen has the ability to spr

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Helal, Ismail M., Ashraf El-Bessoumy, Erwa Al-Bataineh, et al. "Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia, over Drug Resistant Isolates." BioMed Research International 2019 (January 17, 2019): 1–9. http://dx.doi.org/10.1155/2019/8928306.

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Antimicrobial resistance (AMR) is a recurring global problem, which constantly demands new antimicrobial compounds to challenge the resistance. It is well known that essential oils (EOs) have been known for biological activities including antimicrobial properties. In this study, EOs from seven aromatic plants of Asir region of southwestern Saudi Arabia were tested for their antimicrobial efficacy against four drug resistant pathogenic bacterial isolates (Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, and Streptococcus typhimurium) and one fungal isolate (Candida albicans). Ch

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4

Chmielarczyk, Agnieszka, Monika Pomorska-Wesołowska, Dorota Romaniszyn, and Jadwiga Wójkowska-Mach. "Healthcare-Associated Laboratory-Confirmed Bloodstream Infections—Species Diversity and Resistance Mechanisms, a Four-Year Retrospective Laboratory-Based Study in the South of Poland." International Journal of Environmental Research and Public Health 18, no. 5 (2021): 2785. http://dx.doi.org/10.3390/ijerph18052785.

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Introduction: Regardless of the country, advancements in medical care and infection prevention and control of bloodstream infections (BSIs) are an enormous burden of modern medicine. Objectives: The aim of our study was to describe the epidemiology and drug-resistance of laboratory-confirmed BSI (LC-BSIs) among adult patients of 16 hospitals in the south of Poland. Patients and methods: Data on 4218 LC-BSIs were collected between 2016–2019. The identification of the strains was performed using MALDI-TOF. Resistance mechanisms were investigated according to European Committee on Antimicrobial S

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5

Gunasekharan, Mohanapriya, Tae-Ik Choi, Yaya Rukayadi, et al. "Preliminary Insight of Pyrrolylated-Chalcones as New Anti-Methicillin-Resistant Staphylococcus aureus (Anti-MRSA) Agents." Molecules 26, no. 17 (2021): 5314. http://dx.doi.org/10.3390/molecules26175314.

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Bacterial infections are regarded as one of the leading causes of fatal morbidity and death in patients infected with diseases. The ability of microorganisms, particularly methicillin-resistant Staphylococcus aureus (MRSA), to develop resistance to current drugs has evoked the need for a continuous search for new drugs with better efficacies. Hence, a series of non-PAINS associated pyrrolylated-chalcones (1–15) were synthesized and evaluated for their potency against MRSA. The hydroxyl-containing compounds (8, 9, and 10) showed the most significant anti-MRSA efficiency, with the MIC and MBC va

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6

Tanomsridachchai, Wimonrat, Kanjana Changkaew, Ruchirada Changkwanyeun, et al. "Antimicrobial Resistance and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Slaughtered Pigs and Pork in the Central Region of Thailand." Antibiotics 10, no. 2 (2021): 206. http://dx.doi.org/10.3390/antibiotics10020206.

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Methicillin-resistant Staphylococcus aureus (MRSA) have been a major public health concern in humans. Among MRSA, livestock-associated (LA)-MRSA strains have always been associated with exposure to livestock or their products and have emerged in different countries globally. Although studies have identified LA-MRSA from healthy pigs and pork in Thailand, prevalence in slaughtered pigs is still unknown. In addition, there are few reports on the epidemiology and molecular characteristics of LA-MRSA in Thailand. Hence, this is the first report investigating the epidemiology and molecular characte

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7

Alhusadi, Nesrin Atiah, Bengisu Turgutalp, Inci Deniz, et al. "Synthesis, Antimicrobial, Antioxidant and Molecular Docking Studies on Novel 6-Methoxybenzothiazole-piperazine Derivatives with Propanamide Chain." Current Topics in Medicinal Chemistry 20, no. 19 (2020): 1733–41. http://dx.doi.org/10.2174/1568026620666200618122500.

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Background: Infectious diseases are a major threat in the developing world and the discovery of novel antimicrobial agents remains to be crucial due to acquired resistance by the microorganisms. Additionally, various diseases can be prevented with antioxidant agents as they can eliminate the harmful effects of reactive oxygen species. Objective: In this study, it was aimed to synthesize novel compounds bearing N-(6- methoxybenzothiazol-2-yl)-3-(4-substitued piperazinyl)propanamide backbone that had antimicrobial and antioxidant activities. Mechanisms of activity were aimed to be revealed by do

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8

Quemener, Maxence, Marie Dayras, Nicolas Frotté, et al. "Highlighting the Biotechnological Potential of Deep Oceanic Crust Fungi through the Prism of Their Antimicrobial Activity." Marine Drugs 19, no. 8 (2021): 411. http://dx.doi.org/10.3390/md19080411.

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Among the different tools to address the antibiotic resistance crisis, bioprospecting in complex uncharted habitats to detect novel microorganisms putatively producing original antimicrobial compounds can definitely increase the current therapeutic arsenal of antibiotics. Fungi from numerous habitats have been widely screened for their ability to express specific biosynthetic gene clusters (BGCs) involved in the synthesis of antimicrobial compounds. Here, a collection of unique 75 deep oceanic crust fungi was screened to evaluate their biotechnological potential through the prism of their anti

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9

Kosikowska-Adamus, Paulina, Emilia Sikorska, Dariusz Wyrzykowski, et al. "Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach." International Journal of Molecular Sciences 22, no. 13 (2021): 6679. http://dx.doi.org/10.3390/ijms22136679.

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The alarming raise of multi-drug resistance among human microbial pathogens makes the development of novel therapeutics a priority task. In contrast to conventional antibiotics, antimicrobial peptides (AMPs), besides evoking a broad spectrum of activity against microorganisms, could offer additional benefits, such as the ability to neutralize toxins, modulate inflammatory response, eradicate bacterial and fungal biofilms or prevent their development. The latter properties are of special interest, as most antibiotics available on the market have limited ability to diffuse through rigid structur

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10

Karunanidhi, Arunkumar, Ehsanollah Ghaznavi-Rad, Rukman Awang Hamat, et al. "Antibacterial and Antibiofilm Activities of Nonpolar Extracts of Allium stipitatum Regel. against Multidrug Resistant Bacteria." BioMed Research International 2018 (July 11, 2018): 1–13. http://dx.doi.org/10.1155/2018/9845075.

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The present study assessed the in vitro antibacterial and antibiofilm potential of hexane (ASHE) and dichloromethane (ASDE) extracts of Allium stipitatum (Persian shallot) against planktonic cells and biofilm structures of clinically significant antibiotic resistant pathogens, with a special emphasis on methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), and emerging pathogens, Acinetobacter baumannii and Stenotrophomonas maltophilia. Antibacterial activities were determined through disk diffusion, minimum inhibitory concentration (MIC), minimum bacteric

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11

Rante, Herlina, Subehan ., Retno Wulandari, and Yayu Mulsiani Evary. "ANTIBACTERIAL ACTIVITY OF ROBUSTA COFFEE (Coffea robusta L.) PEEL EXTRACT AGAINST HUMAN PATHOGENIC BACTERIA." Journal of Experimental Biology and Agricultural Sciences 9, Spl-2-ICOPMES_2020 (2021): S264—S268. http://dx.doi.org/10.18006/2021.9(spl-2-icopmes_2020).s264.s268.

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Now in these days infectious diseases seriously affect human health and sometimes these infections might become the cause of human mortality. Most of these infectious diseases are caused by bacteria, viruses, and fungi. Although large numbers of antibiotics are available increasing drug resistance in these microorganisms became a serious matter of concern in the scientific community. There is an urgent need for research on alternate natural products that can manage these pathogenic microorganisms without inducing any resistance. The purpose of this study was to determine the antibacterial acti

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12

Mitache, Mihaela Magdalena, Otilia Banu, Elvira Borcan, et al. "Resistance and Virulence Patterns in Gram Negative and Gram Positives Rods Isolated from the Hospital Environment in Bucharest, Romania." Revista de Chimie 69, no. 11 (2018): 3126–32. http://dx.doi.org/10.37358/rc.18.11.6697.

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We aimed to investigate the antibiotic resistance�and virulence�markers in�Gram negative bacilli (GNB) and Gram positives coccus (GPC), strains recently isolated from the�hospital environment and from patients with surgical wound infections in order to obtain epidemiologically relevant data.The strains identification was performed with�the automated miniApi system. The resistance�phenotypes were established�using disk diffusion (CLSI, 2017). 61 strains were screened for the production of enzymatic soluble virulence factors: hemolysins, amylase, caseinase, aesculin hydrolysis, DNA-ase, lipase,

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13

Ribeiro, Sofia Oliveira, Stéphanie Fraselle, Dominique Baudoux, Abdesselam Zhiri, Caroline Stévigny, and Florence Souard. "Proposals for Antimicrobial Testing Guidelines Applied on Ajowan and Spanish Lavender Essential Oils." Planta Medica 87, no. 10/11 (2021): 754–63. http://dx.doi.org/10.1055/a-1475-0020.

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AbstractTo fight the rising resistance of microorganisms to antibiotics, a strategy followed by several researchers is to focus on natural compounds, such as essential oils, as a source of potent antibacterial compounds. These last decades, hundreds of original papers have been written about microbiological assays that prove the antibacterial activity of essential oils and their use in the medical field. But can we really compare all the data available in the literature when the raw material, the microbiological assays, and/or the strains are different from one article to another? This review

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14

Vlad, Ilinca Margareta, Diana Camelia Nuță, Robert Viorel Ancuceanu, et al. "New O-Aryl-Carbamoyl-Oxymino-Fluorene Derivatives with MI-Crobicidal and Antibiofilm Activity Enhanced by Combination with Iron Oxide Nanoparticles." Molecules 26, no. 10 (2021): 3002. http://dx.doi.org/10.3390/molecules26103002.

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Antimicrobial resistance is one of the major public health threats at the global level, urging the search for new antimicrobial molecules. The fluorene nucleus is a component of different bioactive compounds, exhibiting diverse pharmacological actions. The present work describes the synthesis, chemical structure elucidation, and bioactivity of new O-aryl-carbamoyl-oxymino-fluorene derivatives and the contribution of iron oxide nanoparticles to enhance the desired biological activity. The antimicrobial activity assessed against three bacterial and fungal strains, in suspension and biofilm growt

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15

Akusheva, D. N., О. Е. Khokhlova, V. V. Kamshilova, et al. "COMMUNITY-ACQUIRED PNEUMONIA IN HIV-INFECTED SUBJECTS: MICROFLORA, ANTIBIOTIC RESISTANCE: DEPENDENCE ON THE LEVELS OF CD4 LYMPHOCYTES." Medical Immunology (Russia) 21, no. 3 (2019): 457–66. http://dx.doi.org/10.15789/1563-0625-2019-3-457-466.

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Purulent inflammatory diseases of various types and etiology comprise major causes of death among the HIV-infected individuals. The purpose of this work was to determine a variety of communityacquired pathogens causing pneumonia, their antibiotic resistance profiles, and dependence on the CD4 lymphocyte levels, as well as identification of methicillin-resistant Staphylococcus aureus species and their molecular genetic characteristics in HIV-infected patients from the Krasnoyarsk City. Over the period of 2012 to 2016, we have examined 152 HIV-infected patients at the Clinical Pulmonology Depart

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16

Bibi Sadeer, Nabeelah, Juliano G. Haddad, Mohammed Oday Ezzat, et al. "Bruguiera gymnorhiza (L.) Lam. at the Forefront of Pharma to Confront Zika Virus and Microbial Infections—An In Vitro and In Silico Perspective." Molecules 26, no. 19 (2021): 5768. http://dx.doi.org/10.3390/molecules26195768.

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The recent emergence of Zika virus (ZIKV) in Brazil and the increasing resistance developed by pathogenic bacteria to nearly all existing antibiotics should be taken as a wakeup call for the international authority as this represents a risk for global public health. The lack of antiviral drugs and effective antibiotics on the market triggers the need to search for safe therapeutics from medicinal plants to fight viral and microbial infections. In the present study, we investigated whether a mangrove plant, Bruguiera gymnorhiza (L.) Lam. (B. gymnorhiza) collected in Mauritius, possesses antimic

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17

Caiana, Rodrigo Ribeiro Alves, Joyse Maria Braga dos Santos, Josivan Pereira da Silva Júnior, Jadson de Farias Silva, Wylly Araújo de Oliveira та Juliano Carlo Rufino Freitas. "Síntese e avaliação antifúngica do benzil 2,3-didesoxi-α-D-eritro-hex-2-enopiranosídeo contra espécies de Candida spp. e estudo da associação com anfotericina B". ARCHIVES OF HEALTH INVESTIGATION 9, № 5 (2020): 395–402. http://dx.doi.org/10.21270/archi.v9i5.4867.

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Introdução: O número crescente de infecções causadas por fungos e o surgimento de microrganismos resistentes tem sinalizado a necessidade da busca por novos agentes antifúngicos, fomentando a pesquisa em moléculas promissoras, como os O-glicosídeos. Objetivo: Partindo dessa premissa, objetivamos a síntese e investigação da atividade antifúngica do benzil 2,3-didesoxi-α-D-eritro-hex-2-enopiranosídeo isolado e quando associado com a anfotericina B. Material e métodos: Inicialmente foi sintetizado o benzil 4,6-di-O-acetil-2,3-didesoxi-α-D-eritro-hex-2-enopiranosídeo a partir da reação entre o 3,4

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18

Martínez-Vázquez, Ana Verónica, Iliana Berenice Guardiola-Avila, Rebeca Flores-Magallón, Gildardo Rivera, and Virgilio Bocanegra-García. "Detection of multi-drug resistance and methicillin-resistant Staphylococcus aureus (MRSA) isolates from retail meat in Tamaulipas, Mexico." Annals of Microbiology 71, no. 1 (2021). http://dx.doi.org/10.1186/s13213-021-01627-7.

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Abstract Purpose Among the principal microorganisms transmitted to humans by foods of animal origin, Staphylococcus aureus stands out, causing a variety of diseases and with a wide potential for acquiring antimicrobial resistance. This work aimed to determine the prevalence of S. aureus, its multi-drug resistance (MDRSA), and the identification of methicillin-resistant Staphylococcus aureus (MRSA) in retail beef and pork in the state of Tamaulipas, Mexico. Methods S. aureus strains isolated from retail meat were characterized by microbiological and molecular methods to determine phenotypic dru

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19

Zhang, Tiantian, Zhiqiang Niu, Feng Wu, et al. "Qualitative and quantitative detection of surgical pathogenic microorganisms Escherichia coli and Staphylococcus aureus based on ddPCR system." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-87824-5.

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AbstractBacterial culture and drug susceptibility testing are used to identify pathogen infections. Nevertheless, the process requires several days from collection to the identification of bacterial species and drug-resistance patterns. The digital PCR system is a rapidly developing quantitative detection technology widely applied to molecular diagnosis, including copy number variations, single nucleotide variant analysis, cancer biomarker discovery, and pathogen identification. This study aimed to use a droplet digital PCR system to identify bacteria in blood samples and explore its ability t

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20

Gan, Ting, Gang Shu, Hualin Fu, et al. "Antimicrobial resistance and genotyping of Staphylococcus aureus obtained from food animals in Sichuan Province, China." BMC Veterinary Research 17, no. 1 (2021). http://dx.doi.org/10.1186/s12917-021-02884-z.

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Abstract Background Staphylococcus aureus (S. aureus), especially methicillin-resistant Staphylococcus aureus (MRSA), is considered a common zoonotic pathogen, causing severe infections. The objective of this study was to investigate the antimicrobial susceptibility, resistance genes and molecular epidemiology among MRSA and methicillin-susceptible Staphylococcus aureus (MSSA) isolated from food animals in Sichuan Province, China. Methods This study was conducted on 236 S. aureus isolates. All isolates were subjected to antimicrobial susceptibility testing by using a standard microbroth diluti

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21

Jassim, Sundus A., and Nuha J. Kandala. "Molecular Detection of Enterotoxin Genes of Multiresistant Staphylococcus aureus Isolates from Different Sources of Food." Iraqi Journal of Science, January 30, 2021, 61–74. http://dx.doi.org/10.24996/ijs.2021.62.1.6.

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Foodborne diseases are a major risk for human health. Millions of people become sick as a result of eating contaminated food with microorganisms that cause diseases. S. aureus is considered as one of the most important pathogenic bacteria, having the ability to activate certain genes that encode for heat stable enterotoxins and cause Staphylococcal food poisoning. Thus, this study aimed to determine the prevalence of multi resistant Staphylococcus aureus that produce enterotoxins in different sources of food . Forty nine isolates were identified as S.aureus, according to morphological and bioc

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22

Azuonwu, Testimonies Chikanka, and David N. Ogbonna. "Resistant Genes of Microbes Associated with Abattoir Wastes." Journal of Advances in Medical and Pharmaceutical Sciences, August 30, 2019, 1–11. http://dx.doi.org/10.9734/jamps/2019/v21i230130.

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Antimicrobial drug resistance has become prominent as a universal health threat. This has been studied not only in humans but food animals as well. Many genes located on the chromosomal DNA of bacteria have been linked with drug resistance. It is therefore crucial that its occurrence in abattoirs where these animals are slaughtered be studied. This study was thus aimed at identifying some resistance genes in microbes isolated from abattoir ecologies. One hundred and eighty (180) samples consisting of service water, waste blood, wastewater, soil and faecal matter collected from Iwofe, Rumuoduma

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