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Journal articles on the topic 'Status Epilepticus'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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1

Janszky, József, Beáta Bóné, Réka Horváth, Zsófia Sütő, László Szapáry, Vera Juhos, Sámuel Komoly, and Norbert Kovács. "Status epilepticus 2020." Orvosi Hetilap 161, no. 42 (October 18, 2020): 1779–86. http://dx.doi.org/10.1556/650.2020.31908.

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Absztrakt: A status epilepticus a második leggyakoribb, sürgősségi kezelést igénylő neurológiai állapot. Halálozása 15–25%. A „time is brain” elve a status epilepticus kezelésére is igaz: minél korábban kezdjük a megfelelő kezelést, annál nagyobb valószínűséggel tudjuk megállítani a progressziót. Magas szintű evidenciákon alapuló kezelési protokollal a status epilepticus progressziója az esetek 75–90%-ában megelőzhető, az indukált kóma és a halálos kimenetel elkerülhető. A status epilepticus kezelése akkor a legsikeresebb, ha már a korai szakban megkezdjük a parenteralis benzodiazepinterápiát: im. midazolám (0,2 mg/tskg, max. 10 mg). Szabad véna esetén lehet vénásan is adni a benzodiazepint (10 mg diazepám iv). Ha az első benzodiazepinbolusra nem reagál a status epilepticus, állandósult (benzodiazepinrefrakter) status epilepticusról beszélünk. Ilyenkor a benzodiazepin ismétlésével párhuzamosan nem benzodiazepin típusú, gyorsan ható vénás antiepileptikumot is adni kell: iv. valproát (40 mg/kg, max. 3000 mg, 10 perc alatt) vagy levetiracetám (60 mg/kg, max. 4500 mg, 10 perc alatt) javasolt. Az 1 órán túl is tartó, sem benzodiazepinre, sem antiepileptikumra nem reagáló, refrakter status epilepticust neurointenzív osztályon, teljes narcosissal (indukált kómával) kell kezelni. Az indukált kómát gyors hatású anesztetikummal lehet elérni, elsősorban propofol–midazolám kombinációval. Orv Hetil. 2020; 161(42): 1779–1786.

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2

Mandei, Jose M., and Praevilia M. Salendu. "Tatalaksana Status Epileptikus Terkini pada Anak." e-CliniC 11, no. 1 (December 20, 2022): 146–56. http://dx.doi.org/10.35790/ecl.v11i1.44460.

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Absract: Status epilepticus is one of the most common pediatric neurologic emergencies in children with progressive benzodiazepine pharmaco-resistance due to neurotransmitter receptor disturbance. This has led to revisions of definitions and guidelines to emphasize early treatment and faster escalation. The initial management of the stabilization phase is followed by the administration of benzodiazepines as the first line. Second-line medications such as valproate, fosphenytoin, or levetiracetam, or phenobarbital are recommended, and at this point there is no clear evidence that one of these options is better than the other. If seizures persist after second-line drugs, refractory status epilepticus may be established. Treatment of refractory status epilepticus consists of bolus doses and continuous infusion titration with third-line drugs. In conclusion, potential therapeutic approaches for future study may require consideration of interventions that may speed the diagnosis and treatment of status epilepticus. Major advances in the clinical field with new definitions and classifications give the clinicians a better guidance on when to treat, how aggressively to treat, and how to avoid over- or under-treating the condition of status epilepticus. Keywords: status epilepticus; management; children Abstrak: Status epileptikus merupakan salah satu kedaruratan neurologis yang paling umum pada anak dengan farmakoresistensi benzodiazepine progresif karena gangguan reseptor neurotransmiter. Hal ini menyebabkan dilakukannya revisi definisi dan pedoman untuk menekankan pengobatan dini dan eskalasi yang lebih cepat. Tatalaksana awal fase stabilisasi dilanjutkan pemberian benzodiazepine sebagai lini pertama. Pengobatan lini kedua seperti valproate, fosphenytoin, atau levetiracetam, atau fenobarbital direkomendasikan, dan pada titik ini tidak ada bukti yang jelas bahwa salah satu dari opsi ini lebih baik daripada yang lain. Jika kejang berlanjut setelah obat lini kedua, status epileptikus refrakter dapat ditegakkan. Pengobatan status epileptikus refrakter terdiri dari dosis bolus dan titrasi infus kontinu dengan obat lini ketiga. Simpulan studi ini ialah pendekatan terapeutik potensial untuk studi masa depan mungkin memerlukan pertimbangan intervensi yang dapat mempercepat diagnosis dan pengobatan status epileptikus. Kemajuan besar dalam bidang klinis dengan definisi dan klasifikasi baru memberikan panduan yang lebih baik kepada dokter tentang kapan harus mengobati, seberapa agresif untuk mengobati, dan bagaimana menghindari pengobatan yang berlebihan atau kurang dari kondisi stastus epileptikus. Kata kunci: status epileptikus; tatalaksana; anak

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3

Nelson, Sarah E., and Panayiotis N. Varelas. "Status Epilepticus, Refractory Status Epilepticus, and Super-refractory Status Epilepticus." CONTINUUM: Lifelong Learning in Neurology 24, no. 6 (December 2018): 1683–707. http://dx.doi.org/10.1212/con.0000000000000668.

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4

Di Bonaventura, C., F. Mari, N. Vanacore, J. Fattouch, A. Zarabla, A. Berardelli, M. Manfredi, M. Prencipe, and A. T. Giallonardo. "Status epilepticus in epileptic patients." Seizure 17, no. 6 (September 2008): 535–48. http://dx.doi.org/10.1016/j.seizure.2008.02.002.

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5

Gainetdinova, Guzel R., and Tatiana V. Danilova. "Epidemiology, clinic and diagnosis of status epilepticus in adults: A review." Consilium Medicum 24, no. 11 (January 5, 2023): 805–10. http://dx.doi.org/10.26442/20751753.2022.11.201958.

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Status epilepticus is one of the causes of impaired consciousness. Status epilepticus can develop both in patients with epilepsy and in patients without an epileptic history. The most difficult diagnostic task is to identify non-convulsive status epilepticus. The most frequently discussed in the literature issues of the clinical picture, diagnosis of different variants of status epilepticus were analyzed. Particular attention was paid to the peculiarities of status epilepticus in patients of older age groups.

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6

Trinka, Eugen, and Markus Leitinger. "Management of Status Epilepticus, Refractory Status Epilepticus, and Super-refractory Status Epilepticus." CONTINUUM: Lifelong Learning in Neurology 28, no. 2 (April 2022): 559–602. http://dx.doi.org/10.1212/con.0000000000001103.

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7

Abend, Nicholas S., David Bearden, Ingo Helbig, Jennifer McGuire, Sona Narula, Jessica A. Panzer, Alexis Topjian, and Dennis J. Dlugos. "Status Epilepticus and Refractory Status Epilepticus Management." Seminars in Pediatric Neurology 21, no. 4 (December 2014): 263–74. http://dx.doi.org/10.1016/j.spen.2014.12.006.

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8

Karantali, Eleni, Symela Chatzikonstantinou, Ioannis Mavroudis, Constantin Trus, and Dimitrios Kazis. "Cognitive Status Epilepticus: Two Case Reports." Medicina 57, no. 8 (August 3, 2021): 799. http://dx.doi.org/10.3390/medicina57080799.

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Cognitive status epilepticus is an uncommon form of focal status epilepticus presenting with a dysfunction of language, thinking or associated higher cortical functions. The absence of ictal manifestations can be misleading and delay a prompt diagnosis. Here we present two patients; one with amnesic and one with aphasic status epilepticus. Through these cases, we aim to highlight the value of EEG performance early in the diagnostic work-up and early antiepileptic drug initiation in cases where an epileptic disorder cannot be excluded.

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9

Hasan, H., Caner F. Demir, and Hasan S. Cura. "Absence status seen in an adult patient." Journal of Neurosciences in Rural Practice 04, no. 03 (July 2013): 342–44. http://dx.doi.org/10.4103/0976-3147.118809.

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ABSTRACTAbsence status epilepticus (ASE) is a type of nonconvulsive status epilepticus in which continuous or recurrent generalized epileptiform discharges are associated with a varying grade of consciousness impairment. Absence status epilepticus may be obtained during progress of many epileptic syndromes, in several metabolic disturbances and related to use of several drugs. Absence status epilepticus is generally seen in childhood; rarely it can be seen in adulthood. In this paper, the case which has never diagnosed until now in spite of many absence seizures for years, applied for absence seizures to our clinic and diagnosed for juvenile absence epilepsy, has been discussed.

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10

Kumar, Dileep, Awais Bashir Larik, and Amir Shahzad. "CONVULSIVE STATUS EPILEPTICUS." Professional Medical Journal 23, no. 06 (June 10, 2016): 660–64. http://dx.doi.org/10.29309/tpmj/2016.23.06.1603.

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Objectives: To determine the in hospital mortality of convulsive status epilepticusin a tertiary care facility. Study Design: Cross sectional study. Place and Duration of Study:Neurology ward, Jinnah Postgraduate Medical Centre, Karachi, Medicine Department ofPeoples University Of Medical And Health Sciences Nawabshah from July 2015- Dec 2015.Material and Methods: All patients of either gender with age >15 years with status epilepticus,were included in the study. A detailed clinical history and relevant neurological examinationwas performed. All the patients who fulfill the inclusion criteria were enrolled in the study afterinformed written consent and explanation of the study protocol. All the information including inhospital mortality was entered on annexed proforma. All the patients were observed three to fivedays. Results: A total of 108 patients were included in this study fulfilling the inclusion criteria.The overall mean age of these patients was 31.3 ± 13.5 years. The age range of these patientswas 16 to 76 years. History of epilepsy was found in 106 (93.5%) of the patients, 88 (81.5%) ofthe patients had status epilepticus in past, 56 (51.9%) of the patients had drug withdrawal, 20(18.5%) of the patients had febrile illness and 2 (1.9%) of the patients had in hospital mortality.There was no statistical significance proportion difference was observed when comparedgender, history of epilepsy and status of epilepticus in past by in hospital mortality (p-values>0.05). Statistical significance proportion difference (p-value <0.05) was found in age and inhospital mortality. Conclusion: We recommend further studies to reach the firm conclusion.

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11

Momcilovic-Kostadinovic, Dragana, Perisa Simonovic, Dusan Kolar, and Nebojsa Jovic. "Chlorpromazine-induced status epilepticus: A case report." Srpski arhiv za celokupno lekarstvo 141, no. 9-10 (2013): 667–70. http://dx.doi.org/10.2298/sarh1310667m.

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Introduction. It is largely known that some antipsychotic agents could have proconvulsive and proepileptogenic effects in some patients and could induce EEG abnormalities as well. However, the association of status epilepticus with certain antipsychotic drugs has been very rarely reported. Case Report. A case of an 18-year-old adolescent girl, with chlorpromazine therapy started for anxiety-phobic disorder was reported. Her personal history disclosed delayed psychomotor development. Shortly after the introduction of the neuroleptic chlorpromazine therapy in minimal daily dose (37.5 mg), she developed myoclonic status epilepticus, confirmed by the EEG records. Frequent, symmetrical bilateral myoclonic jerks and altered behavior were associated with bilateral epileptiform discharges of polyspikes and spike-wave complexes. This epileptic event lasted 3.5 hours and it was stopped by the parenteral administration of valproate and lorazepam; she was EEG monitored until stable remission. Status epilepticus as initial epileptic event induced by neuroleptic agent was not previously reported in our national literature. Conclusion. Introduction of chlorpromazine to a patient without history of seizures is associated with the evolution of an epileptic activity, including the occurrence of status epilepticus. Clinical evaluation of the risk factors possibly related to chlorpromazine-induced seizure is recommended in individual patients before administering this drug.

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12

Wilner, Andrew N., and Peter R. Bream. "Status epilepticus and pseudostatus epilepticus." Seizure 2, no. 3 (September 1993): 257–60. http://dx.doi.org/10.1016/s1059-1311(05)80136-0.

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13

Thomas, SanjeevV, and Ajith Cherian. "Status epilepticus." Annals of Indian Academy of Neurology 12, no. 3 (2009): 140. http://dx.doi.org/10.4103/0972-2327.56312.

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14

Tejeiro Martínez, José, and Blanca Gómez Sereno. "Status epilepticus." Revista de Neurología 36, no. 07 (2003): 661. http://dx.doi.org/10.33588/rn.3607.2002536.

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15

Millichap, J. Gordon. "Status Epilepticus." Pediatric Neurology Briefs 3, no. 3 (March 1, 1989): 17. http://dx.doi.org/10.15844/pedneurbriefs-3-3-1.

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16

AICARDI, JEAN, and JEAN-JACQUES CHEVRIE. "Status Epilepticus." Pediatrics 84, no. 5 (November 1, 1989): 939–40. http://dx.doi.org/10.1542/peds.84.5.939a.

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Concerning the article by Maytal and colleagues and the accompanying editorial by Freeman, we have also found that the mortality and morbidity of cryptogenic status epilepticus has decreased considerably since our 1970 paper. Likewise, the incidence of acquired hemiplegia in France has become low during the same period. Contrary to Maytal et al, however, we believe that better and earlier control of convulsive status has played a role in this decrease. There is considerable evidence that convulsive seizures can produce brain damage, irrespective of the cause of attacks.

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17

&NA;. "Status epilepticus." Drugs & Therapy Perspectives 3, no. 8 (May 1994): 8–12. http://dx.doi.org/10.2165/00042310-199403080-00004.

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18

Bauer, J. "Status epilepticus." Aktuelle Neurologie 23, no. 01 (February 1996): 32–35. http://dx.doi.org/10.1055/s-2007-1017830.

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19

Takahashi, Akihiko, Hiroshi Ohno, Hirobumi Wakatabe, Jun Ishigooka, Masaaki Inami, and Mitsukumi Murasaki. "Status Epilepticus." Psychiatry and Clinical Neurosciences 43, no. 3 (September 1989): 522–23. http://dx.doi.org/10.1111/j.1440-1819.1989.tb02966.x.

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20

Kelso, A. R. C., and H. R. Cock. "Status epilepticus." Practical Neurology 5, no. 6 (December 2005): 322–33. http://dx.doi.org/10.1111/j.1474-7766.2005.00347.x.

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21

Katz, Steven. "Status Epilepticus." Pediatric Emergency Care 21, no. 12 (December 2005): 883–84. http://dx.doi.org/10.1097/01.pec.0000200298.31605.99.

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22

Feen, Eliahu S., Eric M. Bershad, and Jose I. Suarez. "Status Epilepticus." Southern Medical Journal 101, no. 4 (April 2008): 400–406. http://dx.doi.org/10.1097/smj.0b013e31816852b0.

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23

King, Brent R. "Status Epilepticus." Emergency Medicine News 27, no. 5 (May 2005): 22–23. http://dx.doi.org/10.1097/00132981-200505000-00025.

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24

Marchi, Nicola A., Jan Novy, Mohamed Faouzi, Christine Stähli, Bernard Burnand, and Andrea O. Rossetti. "Status Epilepticus." Critical Care Medicine 43, no. 5 (May 2015): 1003–9. http://dx.doi.org/10.1097/ccm.0000000000000881.

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25

kelly, Maryann. "Status Epilepticus." AJN, American Journal of Nursing 95, no. 8 (August 1995): 50. http://dx.doi.org/10.1097/00000446-199508000-00026.

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26

Manno, Edward M. "Status Epilepticus." Neurohospitalist 1, no. 1 (January 2011): 23–31. http://dx.doi.org/10.1177/1941875210383176.

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27

Merkenschlager, Andreas, and Werner Siekmeyer. "Status epilepticus." Kinder- und Jugendmedizin 03, no. 02 (2003): 83–86. http://dx.doi.org/10.1055/s-0037-1617772.

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ZsuammenfassungWir sprechen von einem Status epilepticus (SE), wenn ein kontinuierlicher Anfall oder wiederholte Anfälle ohne zwischenzeitig wiedererlangtes Bewusstsein vorliegen. Der SE stellt einen Notfall dar. Es stehen eine Reihe von medikamentösen Therapien zur Verfügung. Ein klares, schematisch geordnetes Vorgehen erleichtert die adäquate Behandlung. Als Mittel der Wahl haben sich Benzodiazepine bewährt. Alternative Substanzen werden besprochen. Wir stellen einen geeigneten Therapiealgorithmus vor und beschreiben notwendige, allgemeine Basismaßnahmen.

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28

Burghaus, Lothar, Christian Dohmen, and Michael Malter. "Status epilepticus." Fortschritte der Neurologie · Psychiatrie 86, no. 05 (May 2018): 279–86. http://dx.doi.org/10.1055/a-0576-6950.

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ZusammenfassungDer Status epilepticus ist ein neurologischer Notfall, der durch prolongierte Anfallsaktivität oder eine Serie von Anfällen ohne zwischenzeitliche Wiedererlangung des vorbestehenden neurologischen Befundes gekennzeichnet ist. Vorrangiges Ziel der Therapie ist die rasche Beendigung der Anfälle, da mit zunehmender Dauer des Status epilepticus Morbidität und Mortalität ansteigen. Auf der Grundlage von klinischen Studien und Leitlinienempfehlungen werden Strategien zur Behandlung des Status epilepticus vorgestellt.

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29

Seinfeld, Syndi, Howard P. Goodkin, and Shlomo Shinnar. "Status Epilepticus." Cold Spring Harbor Perspectives in Medicine 6, no. 3 (March 2016): a022830. http://dx.doi.org/10.1101/cshperspect.a022830.

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30

Unterberger, Iris. "Status Epilepticus." Journal of Clinical Neurophysiology 33, no. 1 (February 2016): 10–13. http://dx.doi.org/10.1097/wnp.0000000000000222.

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31

Hocker, Sara E. "Status Epilepticus." CONTINUUM: Lifelong Learning in Neurology 21 (October 2015): 1362–83. http://dx.doi.org/10.1212/con.0000000000000225.

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32

Vining, Eileen P. G., and John M. Freeman. "Status Epilepticus." Pediatric Annals 14, no. 11 (November 1, 1985): 764–70. http://dx.doi.org/10.3928/0090-4481-19851101-14.

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33

Altemeier, William A. "Status Epilepticus." Pediatric Annals 28, no. 4 (April 1, 1999): 206–8. http://dx.doi.org/10.3928/0090-4481-19990401-03.

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34

Lowenstein, Daniel H., and Brian K. Alldredge. "Status Epilepticus." New England Journal of Medicine 338, no. 14 (April 2, 1998): 970–76. http://dx.doi.org/10.1056/nejm199804023381407.

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35

Press, Craig A., and Kevin E. Chapman. "Status epilepticus." Neurology 92, no. 20 (May 8, 2019): 931–32. http://dx.doi.org/10.1212/wnl.0000000000007494.

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36

Jorch, G. "Status epilepticus." Intensivmedizin up2date 10, no. 04 (November 4, 2014): 277. http://dx.doi.org/10.1055/s-0034-1389761.

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37

Schroeder, Donna J., and Brian K. Alldredge. "Status Epilepticus." Journal of Pharmacy Practice 6, no. 6 (December 1993): 271–77. http://dx.doi.org/10.1177/089719009300600603.

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Status epilepticus is a medical emergency that requires prompt intervention with effective anticonvulsant drug therapy to minimize the risk of morbidity and mortality. Although status epilepticus can occur as the first presentation of seizures, it is more common in patients who have a history of epilepsy. Metabolic disturbances, stroke, infection, and head trauma can also precipitate repetitive or continuous seizures and, if possible, the underlying etiology should be corrected as the first step in effective management. Permanent neurological sequelae are more likely as the duration of status epilepticus exceeds 90 minutes. In this regard, it is essential that anticonvulsant drug therapy is initiated as soon as possible. Benzodiazepines (diazepam, Iorazepam) are commonly used as the agents of choice for early termination of status epilepticus. Phenytoin and phenobarbital are also useful because of their long-lasting anticonvulsant effects. Other agents that may be useful under special circumstances include midazolam, fosphenytoin (phenytoin prodrug), sodium valproate, paraldehyde, and high-dose barbiturates.

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38

Treiman, David M. "Status epilepticus." Current Opinion in Critical Care 1, no. 2 (April 1995): 104–10. http://dx.doi.org/10.1097/00075198-199504000-00004.

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39

Shields, W. Donald. "Status Epilepticus." Pediatric Clinics of North America 36, no. 2 (April 1989): 383–93. http://dx.doi.org/10.1016/s0031-3955(16)36655-x.

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40

Wroe, S. "Status Epilepticus." Journal of Neurology, Neurosurgery & Psychiatry 62, no. 2 (February 1, 1997): 216. http://dx.doi.org/10.1136/jnnp.62.2.216.

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41

Chang, Cherylee W. J., and Thomas P. Bleck. "Status Epilepticus." Neurologic Clinics 13, no. 3 (August 1995): 529–48. http://dx.doi.org/10.1016/s0733-8619(18)30033-1.

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42

Walsh, Gregory O., and Antonio V. Delgado-Escueta. "Status Epilepticus." Neurologic Clinics 11, no. 4 (November 1993): 835–56. http://dx.doi.org/10.1016/s0733-8619(18)30127-0.

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43

Chapman, M. G., M. Smith, and N. P. Hirsch. "Status epilepticus." Anaesthesia 56, no. 7 (July 2001): 648–59. http://dx.doi.org/10.1046/j.1365-2044.2001.02115.x.

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44

Leppik, Ilo E. "Status Epilepticus." Neurologic Clinics 4, no. 3 (August 1986): 633–43. http://dx.doi.org/10.1016/s0733-8619(18)30967-8.

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45

Jordan, Kenneth G. "Status Epilepticus." Neurosurgery Clinics of North America 5, no. 4 (October 1994): 671–86. http://dx.doi.org/10.1016/s1042-3680(18)30494-7.

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46

Hanhan, Usama A., Mariano R. Fiallos, and James P. Orlowski. "STATUS EPILEPTICUS." Pediatric Clinics of North America 48, no. 3 (June 2001): 683–94. http://dx.doi.org/10.1016/s0031-3955(05)70334-5.

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47

Hirsch, Lawrence J., and Hiba Arif. "STATUS EPILEPTICUS." CONTINUUM: Lifelong Learning in Neurology 13 (August 2007): 121–51. http://dx.doi.org/10.1212/01.con.0000284538.29811.da.

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48

Mirski, Marek A., and Panayiotis N. Varelas. "STATUS EPILEPTICUS." CONTINUUM: Lifelong Learning in Neurology 12 (February 2006): 70–92. http://dx.doi.org/10.1212/01.con.0000290438.87946.a4.

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49

Waterhouse, Elizabeth. "STATUS EPILEPTICUS." CONTINUUM: Lifelong Learning in Neurology 16 (June 2010): 199–227. http://dx.doi.org/10.1212/01.con.0000368239.87728.59.

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50

Hirsch, Lawrence J., and Nicolas Gaspard. "Status Epilepticus." CONTINUUM: Lifelong Learning in Neurology 19 (June 2013): 767–94. http://dx.doi.org/10.1212/01.con.0000431395.16229.5a.

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