Log in

Relevant bibliographies by topics / Staudinger [2+2] cycloaddition / Journal articles

To see the other types of publications on this topic, follow the link: Staudinger [2+2] cycloaddition.

Journal articles on the topic 'Staudinger [2+2] cycloaddition'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Staudinger [2+2] cycloaddition.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

He, Wei, Junpeng Zhuang, Zhanhui Yang, and Jiaxi Xu. "Sterically controlled diastereoselectivity in thio-Staudinger cycloadditions of alkyl/alkenyl/aryl-substituted thioketenes." Organic & Biomolecular Chemistry 15, no. 26 (2017): 5541–48. http://dx.doi.org/10.1039/c7ob01214d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Spruha, A. Gharad, and N. Berad Baliram. "Synthesis, characterization and antibacterial study of 1-arylamido-3-chloro-4- (2-chloroquinolin-3-yl)-azetidin-2-ones." Journal of Indian Chemical Society Vol. 93, Febr 2016 (2016): 223–28. https://doi.org/10.5281/zenodo.5603154.

Full text

Abstract:

Post Graduate Teaching Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440 033, Maharashtra, India <em>E-mail</em> : spruhagharad@gmail.com, bnberad@gmail.com <em>Manuscript received online 28 April 2015, revised 20 May 2015, accepted 22 May 2015</em> A series of quinoline based β-lactams (azetidinones) have been synthesized via cycloaddition reaction (Staudinger reaction) of imines with ketene. The methodology involves [2+2] cycloaddition of Schiff bases with chloroacetyl chloride in presence of triethylamine to yield the corresponding 1-arylamido-3-chloro

APA, Harvard, Vancouver, ISO, and other styles

3

Bakulina, Olga, Dmitry Dar'in та Mikhail Krasavin. "Mixed carboxylic–sulfonic anhydride in reaction with imines: a straightforward route to water-soluble β-lactams via a Staudinger-type reaction". Organic & Biomolecular Chemistry 16, № 21 (2018): 3989–98. http://dx.doi.org/10.1039/c8ob00768c.

Full text

Abstract:

The first example of employing a mixed carboxylic–sulfonic anhydride in reaction with imines is reported. It gave β-lactams, presumably, via a formal [2 + 2] cycloaddition (a Staudinger-type reaction).

APA, Harvard, Vancouver, ISO, and other styles

4

Lu, Nan, Chengxia Miao та Xiaozheng Lan. "Theoretical investigation on diastereoselective [2+2] cycloaddition and Pd-catalyzed enantioselective [3+2] cycloaddition for synthesis of cis-β-lactam and exo-furobenzopyranone". Thermal Science and Engineering 7, № 1 (2024): 5949. http://dx.doi.org/10.24294/tse.v7i1.5949.

Full text

Abstract:

The mechanism is investigated for Wolff rearrangement/Staudinger [2+2] cycloaddition cascade and Pd-catalyzed, decarboxylative, formal [3+2] cycloaddition. Wolff rearrangement of 3-diazotetramic acid is determined to be rate-limiting step generates cyclic acyl ketene. The interaction of ketene with imine firstly results in zwitterion followed by conrotatory cyclization giving major cis-β-lactam. For synthesis of s-VECs, the epoxidation−cyclization cascade and hydrolysis give precursor of better performing exocyclic derivative. The reaction with 3-cyanochromone includes decarboxylation, nucleop

APA, Harvard, Vancouver, ISO, and other styles

5

Ram, Naresh Yadav, Banik Indrani та Krishna Banik Bimal. "Microwave-induced new synthesis of trans and cis 3-phenylthio-4-carboethoxy β-lactams". Journal of Indian Chemical Society Vol. 96, Oct 2019 (2019): 1355–58. https://doi.org/10.5281/zenodo.5642731.

Full text

Abstract:

Department of Chemistry, Faculty of Engineering and Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh, India Department of Chemistry, University of Texas-Pan American,1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas-M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia <em>E-mail</em>: bimalbanik10@gmail.com, bbanik@pmu.edu.sa

APA, Harvard, Vancouver, ISO, and other styles

6

Jarrahpour, Aliasghar, Mohammad Mahdi Doroodmand, and Edris Ebrahimi. "The first report of [2+2] ketene–imine cycloaddition reactions (Staudinger) on carbon nanotubes." Tetrahedron Letters 53, no. 23 (2012): 2797–801. http://dx.doi.org/10.1016/j.tetlet.2012.03.089.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Ram, Naresh Yadav, Kumar Singh Amarendra, Banik Indrani та Krishna Banik Bimal. "Microwave-induced stereospecific synthesis of trans 3-phenylthio β-lactams". Journal of Indian Chemical Society Vol. 96, Oct 2019 (2019): 1359–63. https://doi.org/10.5281/zenodo.5642753.

Full text

Abstract:

Department of Chemistry, Faculty of Engineering and Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh India Department of Chemistry, University of Texas-Pan American, 1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas-M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia <em>E-mail:</em> bimalbanik10@gmail.com; bbanik@pmu.edu.sa

APA, Harvard, Vancouver, ISO, and other styles

8

Leier, Samantha, and Frank Wuest. "Innovative Peptide Bioconjugation Chemistry with Radionuclides: Beyond Classical Click Chemistry." Pharmaceuticals 17, no. 10 (2024): 1270. http://dx.doi.org/10.3390/ph17101270.

Full text

Abstract:

Background: The incorporation of radionuclides into peptides and larger biomolecules requires efficient and sometimes biorthogonal reaction conditions, to which click chemistry provides a convenient approach. Methods: Traditionally, click-based radiolabeling techniques have focused on classical click chemistry, such as copper(I)-catalyzed alkyne-azide [3+2] cycloaddition (CuAAC), strain-promoted azide-alkyne [3+2] cycloaddition (SPAAC), traceless Staudinger ligation, and inverse electron demand Diels–Alder (IEDDA). Results: However, newly emerging click-based radiolabeling techniques, includin

APA, Harvard, Vancouver, ISO, and other styles

9

Fernández, Rosario, Ana Ferrete, José M. Lassaletta, José M. Llera, and Eloísa Martín-Zamora. "N,N-Dialkylhydrazones as the Imine Component in the Staudinger-Like [2+2] Cycloaddition to Benzyloxyketene." Angewandte Chemie 114, no. 5 (2002): 859–61. http://dx.doi.org/10.1002/1521-3757(20020301)114:5<859::aid-ange859>3.0.co;2-k.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Barba, Victor, Cecilia Hernández, Susana Rojas-Lima, Norberto Farfán та Rosa Santillan. "Preparation of N-aryl-substituted spiro-β-lactams via Staudinger cycloaddition". Canadian Journal of Chemistry 77, № 12 (1999): 2025–32. http://dx.doi.org/10.1139/v99-212.

Full text

Abstract:

The interest in the study of β-lactams continues due to their therapeutic importance as antibiotics. In this work, six spiro-β-lactams (7a-7c, 8a-8c) have been prepared using the [2+2] cycloaddition of isomaleimides to acid chlorides. The heterobicyclic structures obtained have been characterized by mass spectrometry, IR, NMR spectroscopy, and for compounds 7a, 7b, and 8b the X-ray crystallographic study showed a nearly planar arrangement for the β-lactam ring.Key words: β-lactams, azetidinone, isomaleimides, ketenes, X-ray crystallography.

APA, Harvard, Vancouver, ISO, and other styles

11

Filatov, Vadim E., Dmitrii A. Iuzabchuk, Viktor A. Tafeenko та ін. "Dispirooxindole-β-Lactams: Synthesis via Staudinger Ketene-Imine Cycloaddition and Biological Evaluation". International Journal of Molecular Sciences 23, № 12 (2022): 6666. http://dx.doi.org/10.3390/ijms23126666.

Full text

Abstract:

In this work, we present the first synthesis of dispirooxindole-β-lactams employing optimized methodology of one-pot Staudinger ketene-imine cycloaddition with N-aryl-2-oxo-pyrrolidine-3-carboxylic acids as the ketene source. Spiroconjugation of indoline-2-one with β-lactams ring is considered to be able to provide stabilization and wide scope of functionalization to resulting scaffolds. The dispipooxindoles obtained demonstrated medium cytotoxicity in the MTT test on A549, MCF7, HEK293, and VA13 cell lines, and one of the compounds demonstrated antibacterial activity against E. coli strain LP

APA, Harvard, Vancouver, ISO, and other styles

12

Levashova, Ekaterina, Olga Bakulina, Dmitry Dar'in, and Mikhail Krasavin. "Catalyst‐Free Synthesis of Diastereomerically Pure 3‐Cyanoazetidin‐2‐ones via Thermally Promoted Tandem Wolff Rearrangement–Staudinger [2+2] Cycloaddition." ChemistrySelect 6, no. 47 (2021): 13582–88. http://dx.doi.org/10.1002/slct.202103446.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Fernandez, Rosario, Ana Ferrete, Jose M. Lassaletta, Jose M. Llera, and Eloisa Martin-Zamora. "ChemInform Abstract: N,N-Dialkylhydrazones as the Imine Component in the Staudinger-Like [2 + 2] Cycloaddition to Benzyloxyketene." ChemInform 33, no. 31 (2010): no. http://dx.doi.org/10.1002/chin.200231111.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Yang, Zhanhui, and Jiaxi Xu. "Annuloselectivity and stereochemistry in the sulfa-Staudinger cycloadditions of cyclic imines." RSC Advances 5, no. 96 (2015): 78396–405. http://dx.doi.org/10.1039/c5ra15717j.

Full text

Abstract:

The annuloselectivity and the stereochemistry in the [2<sup>s</sup>+ 2<sup>i</sup>+ 2<sup>i</sup>] annulations in the sulfa-Staudinger cycloadditions of cyclic imines are controlled by the steric hindrance of cyclic imines. A stepwise [4 + 2] annulation mechanism is proposed.

APA, Harvard, Vancouver, ISO, and other styles

15

Arrieta, Ana, Fernando P. Cossío, and Begoña Lecea. "New Insights on the Origins of the Stereocontrol of the Staudinger Reaction: [2 + 2] Cycloaddition between Ketenes andN-Silylimines." Journal of Organic Chemistry 65, no. 25 (2000): 8458–64. http://dx.doi.org/10.1021/jo0007736.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Del Buttero, Paola, Giorgio Molteni, Antonio Papagni, and Luciano Miozzo. "The [2+2] Staudinger cycloadditive route to enantiopure azetidino[4,1-d][1,4]benzooxazepines." Tetrahedron: Asymmetry 15, no. 16 (2004): 2555–59. http://dx.doi.org/10.1016/j.tetasy.2004.06.037.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Ciccolini, Cecilia, Giacomo Mari, Gianfranco Favi, Fabio Mantellini, Lucia De Crescentini, and Stefania Santeusanio. "Sequential MCR via Staudinger/Aza-Wittig versus Cycloaddition Reaction to Access Diversely Functionalized 1-Amino-1H-Imidazole-2(3H)-Thiones." Molecules 24, no. 20 (2019): 3785. http://dx.doi.org/10.3390/molecules24203785.

Full text

Abstract:

A multicomponent reaction (MCR) strategy, alternative to the known cycloaddition reaction, towards variously substituted 1-amino-1H-imidazole-2(3H)-thione derivatives has been successfully developed. The novel approach involves α-halohydrazones whose azidation process followed by tandem Staudinger/aza-Wittig reaction with CS2 in a sequential MCR regioselectively leads to the target compounds avoiding the formation of the regioisomer iminothiazoline heterocycle. The approach can be applied to a range of differently substituted α-halohydrazones bearing also electron-withdrawing groups confirming

APA, Harvard, Vancouver, ISO, and other styles

18

Kaboudin, Babak, та Mohammad Afsharinezhad. "Synthesis of a Novel Class of β-Lactam Derivatives of 1-Aminophosphonates by Staudinger Ketene-Imine [2+2]-Cycloaddition Reaction". Synthesis 2010, № 20 (2010): 3504–8. http://dx.doi.org/10.1055/s-0030-1257889.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Alcaide, Benito, and Alberto Rodríguez-Vicente. "A convenient trans-stereoselective synthesis of phenanthridine derived 2-azetidinones using the Staudinger ketene-imine cycloaddition." Tetrahedron Letters 40, no. 10 (1999): 2005–6. http://dx.doi.org/10.1016/s0040-4039(99)00102-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Palomo, Claudio, Jesus M. Aizpurua, Iñaki Ganboa та Mikel Oiarbide. "Asymmetric Synthesis of β-Lactams by Staudinger Ketene-Imine Cycloaddition Reaction". European Journal of Organic Chemistry 1999, № 12 (1999): 3223–35. http://dx.doi.org/10.1002/(sici)1099-0690(199912)1999:12<3223::aid-ejoc3223>3.0.co;2-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Kumar, Pradeep, Trapti Aggarwal, and Akhilesh K. Verma. "Chemoselective Azidation of o-Alkynylaldehydes over [3 + 2] Cycloaddition and Subsequent Staudinger Reaction: Access to Benzonaphthyridines/Naphthyridines." Journal of Organic Chemistry 82, no. 12 (2017): 6388–97. http://dx.doi.org/10.1021/acs.joc.7b01016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Jain, Shailja, and Kumar Vanka. "The Effect of Solvent–Substrate Noncovalent Interactions on the Diastereoselectivity in the Intramolecular Carbonyl-Ene and the Staudinger [2 + 2] Cycloaddition Reactions." Journal of Physical Chemistry A 124, no. 39 (2020): 8019–28. http://dx.doi.org/10.1021/acs.jpca.0c05738.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Kaboudin, Babak, та Mohammad Bagher Afsharinezhad. "ChemInform Abstract: Synthesis of a Novel Class of β-Lactam Derivatives of 1-Aminophosphonates by Staudinger Ketene-Imine [2 + 2]-Cycloaddition Reaction." ChemInform 42, № 5 (2011): no. http://dx.doi.org/10.1002/chin.201105092.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Hassan, Sangar A., Media N. Abdullah та Dara M. Aziz. "Synthesis of New Series Bis-3-Chloro-β-Lactam Derivatives from Symmetrical Bis-Schiff Bases as Effective Antimicrobial Agents with Molecular Docking Studies". Science Journal of University of Zakho 9, № 3 (2021): 128–37. http://dx.doi.org/10.25271/sjuoz.2021.9.3.830.

Full text

Abstract:

Endeavoring to find a new type of antimicrobial agents, a new sequence of bis-Schiff bases and bis-3-cholro-β-lactams are synthesized. An astonishing class of strained compounds is part of the symmetrical bis-Schiff bases that has widespread applications and building blocks for the combination of bis-3-cholro-β-lactams antibiotics. Bis-3-cholro-β-lactams are synthesized through (Staudinger) [2+2] ketene-imine cycloaddition reaction. Structures of the produced compounds are deduced by 1H, 13C-NMR, and FT-IR spectroscopies. All produced compounds are shown moderate to good antimicrobial activity

APA, Harvard, Vancouver, ISO, and other styles

25

Alcaide, Benito, and Alberto Rodriguez-Vicente. "ChemInform Abstract: A Convenient trans-Stereoselective Synthesis of Phenanthridine Derived 2-Azetidinones Using the Staudinger Ketene-Imine Cycloaddition." ChemInform 30, no. 23 (2010): no. http://dx.doi.org/10.1002/chin.199923175.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Ma, Xiaoming, Xiaofeng Zhang, Guoshu Xie, John Mark Awad, and Wei Zhang. "One-pot diastereoselective synthesis of tetrahydroepimino-benzo[b]azocines through sequential [3+2]-cycloaddition and Staudinger-aza-Wittig reactions." Tetrahedron Letters 60, no. 40 (2019): 151127. http://dx.doi.org/10.1016/j.tetlet.2019.151127.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Ma, Xiaoming, Xiaofeng Zhang, John Mark Awad, et al. "Sequential decarboxylative [3+2] cycloaddition and Staudinger/aza-Wittig reactions for diastereoselective synthesis of tetrahydro-pyrroloquinazolines and tetrahedro-pyrrolobenzodiazepines." Tetrahedron Letters 61, no. 2 (2020): 151392. http://dx.doi.org/10.1016/j.tetlet.2019.151392.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Habib, Osama M., Asaad S. Mohamed, Yehia A. Ibrahim та Nouria A. Al-Awadi. "Sequential Diimination, Staudinger [2 + 2] Ketene–Imine Cycloaddition, and Ring-Closing Metathesis (RCM) Reactions: In Route to Bis(4-spiro-fused-β-lactams)-Based Macrocycles". Journal of Organic Chemistry 86, № 21 (2021): 14777–85. http://dx.doi.org/10.1021/acs.joc.1c01576.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Handula, Maryana, Kuo-Ting Chen, and Yann Seimbille. "IEDDA: An Attractive Bioorthogonal Reaction for Biomedical Applications." Molecules 26, no. 15 (2021): 4640. http://dx.doi.org/10.3390/molecules26154640.

Full text

Abstract:

The pretargeting strategy has recently emerged in order to overcome the limitations of direct targeting, mainly in the field of radioimmunotherapy (RIT). This strategy is directly dependent on chemical reactions, namely bioorthogonal reactions, which have been developed for their ability to occur under physiological conditions. The Staudinger ligation, the copper catalyzed azide-alkyne cycloaddition (CuAAC) and the strain-promoted [3 + 2] azide–alkyne cycloaddition (SPAAC) were the first bioorthogonal reactions introduced in the literature. However, due to their incomplete biocompatibility and

APA, Harvard, Vancouver, ISO, and other styles

30

Kang, Xueying, Xuekang Cai, Long Yi, and Zhen Xi. "Multifluorinated Aryl Azides for the Development of Improved H 2 S Probes, and Fast Strain‐promoted Azide‐Alkyne Cycloaddition and Staudinger Reactions." Chemistry – An Asian Journal 15, no. 9 (2020): 1420–29. http://dx.doi.org/10.1002/asia.202000005.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

COSSIO, F. P., B. LECEA, C. CUEVAS, A. MIELGO та C. PALOMO. "ChemInform Abstract: A Novel Entry for the Asymmetric Staudinger Reaction: Experimental and Computational Studies on the Formation of β-Lactams Through (2 + 2) Cycloaddition Reaction of Ketenes to Imines". ChemInform 24, № 48 (2010): no. http://dx.doi.org/10.1002/chin.199348303.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Nimbalkar, Urja, Julio Seijas, Rachna Borkute, et al. "Ultrasound Assisted Synthesis of 4-(Benzyloxy)-N-(3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl) Benzamide as Challenging Anti-Tubercular Scaffold." Molecules 23, no. 8 (2018): 1945. http://dx.doi.org/10.3390/molecules23081945.

Full text

Abstract:

A series of ten novel derivatives of 4-(benzyloxy)-N-(3-chloro-2-(substituted phenyl)-4-oxoazetidin-1-yl) benzamide 6a–j were synthesized in good yield from the key compound 4-(benzyloxy)-N′-(substituted benzylidene) benzo hydrazide, called Schiff ’s bases 5a–j, by Staudinger reaction ([2 + 2] ketene-imine cycloaddition reaction) with chloro acetyl chloride in the presence of catalyst tri ethylamine and solvent dimethyl formamide (DMF), by using ultra-sonication as one of the green chemistry tools. All the synthesised compounds were evaluated for in vitro anti-tubercular activity against Mycob

APA, Harvard, Vancouver, ISO, and other styles

33

Leškovskis, Kristaps, Anatoly Mishnev, Irina Novosjolova, and Māris Turks. "SNAr Reactions of 2,4-Diazidopyrido[3,2-d]pyrimidine and Azide-Tetrazole Equilibrium Studies of the Obtained 5-Substituted Tetrazolo[1,5-a]pyrido[2,3-e]pyrimidines." Molecules 27, no. 22 (2022): 7675. http://dx.doi.org/10.3390/molecules27227675.

Full text

Abstract:

A straightforward method for the synthesis of 5-substituted tetrazolo[1,5-a]pyrido[2,3-e]pyrimidines from 2,4-diazidopyrido[3,2-d]pyrimidine in SNAr reactions with N-, O-, and S- nucleophiles has been developed. The various N- and S-substituted products were obtained with yields from 47% to 98%, but the substitution with O-nucleophiles gave lower yields (20–32%). Furthermore, the fused tetrazolo[1,5-a]pyrimidine derivatives can be regarded as 2-azidopyrimidines and functionalized in copper(I)-catalyzed azide-alkyne dipolar cycloaddition (CuAAC) and Staudinger reactions due to the presence of a

APA, Harvard, Vancouver, ISO, and other styles

34

Grabrijan, Katarina, Nika Strašek, and Stanislav Gobec. "Synthesis of 3-Amino-4-substituted Monocyclic ß-Lactams—Important Structural Motifs in Medicinal Chemistry." International Journal of Molecular Sciences 23, no. 1 (2021): 360. http://dx.doi.org/10.3390/ijms23010360.

Full text

Abstract:

Monocyclic ß-lactams (azetidin-2-ones) exhibit a wide range of biological activities, the most important of which are antibacterial, anticancer, and cholesterol absorption inhibitory activities. The synthesis of decorated monocyclic ß-lactams is challenging because their ring is highly constrained and consequently reactive, which is also an important determinant of their biological activity. We present the optimized synthesis of orthogonally protected 3-amino-4-substituted monocyclic ß-lactams. Among several possible synthetic approaches, Staudinger cycloaddition proved to be the most promisin

APA, Harvard, Vancouver, ISO, and other styles

35

Guerrero-Villalobos, Liliana Rocio, and FabiĂˇn Orozco LĂłpez. "RATIONAL DESIGN, SYNTHESIS AND CHARACTERIZATION OF HYBRID MOLECULES WITH PYRAZOLINE, PYRIMIDINE AND THIAZOLIDINE NUCLEI AS POTENTIAL ANTIBACTERIAL AGENTS." CBU International Conference Proceedings 5 (September 24, 2017): 1096–103. http://dx.doi.org/10.12955/cbup.v5.1077.

Full text

Abstract:

In this paper, a set of computational tools were used to design and evaluate molecular structures resulting from the combination of the biologically interesting pyrazoline, aminopyrimidine and thiazolidine nuclei (molecular modification) to obtain new bioactive compounds. Key physicochemical properties were calculated (absorption, distribution, metabolism, excretion and toxicity), to determine the bioavailability of the designed compounds and to perform a preselection of 12 derivatives which were then optimized and studied by molecular docking with the receptor PBP3 (4bjp) from Escherichia col

APA, Harvard, Vancouver, ISO, and other styles

36

Shaikh, A. L., R. N. Yadav, and B. K. Banik. "Microwave-Induced Enantiospecific Synthesis of trans-(3R,4R)-3-Acetoxy-4-aryl-1-(chrysen-6-yl)azetidin-2-ones via the Staudinger Cycloaddition Reaction of (+)-Car-3-ene with Polyaromatic Imines." Russian Journal of Organic Chemistry 56, no. 5 (2020): 910–15. http://dx.doi.org/10.1134/s1070428020050267.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Fernández, Rosario, Ana Ferrete, José M. Lassaletta, José M. Llera, and Eloísa Martín-Zamora. "N,N-Dialkylhydrazones as the Imine Component in the Staudinger-Like [2+2] Cycloaddition to Benzyloxyketene We thank the Dirección General de Investigación Científica y Técnica (grants BQU 2001-2376 and PPQ 2000-1341) and the Junta de Andalucía for financial support. We also thank the Ministerio de Educación y Ciencia for a doctoral fellowship to A.F." Angewandte Chemie International Edition 41, no. 5 (2002): 831. http://dx.doi.org/10.1002/1521-3773(20020301)41:5<831::aid-anie831>3.0.co;2-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Kanematsu, Ken, Noboru Sugimoto, Masayo Kawaoka, Sinkoo Yeo, and Motoo Shiro. "Competitive intramolecular [4+2] cycloaddition and [2+2] cycloaddition of sulfonylallene." Tetrahedron Letters 32, no. 10 (1991): 1351–54. http://dx.doi.org/10.1016/s0040-4039(00)79665-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Kotha, Sambasivarao, Kakali Lahiri, and Gaddamedi Sreevani. "Design and Synthesis of Aromatics through [2+2+2] Cyclotrimerization." Synlett 29, no. 18 (2018): 2342–61. http://dx.doi.org/10.1055/s-0037-1609584.

Full text

Abstract:

The [2+2+2] cycloaddition reaction is a useful tool to realize unusual chemical transformations which are not achievable by traditional methods. Here, we report our work during the past two decades that involve utilization of transition-metal complexes in a [2+2+2] cyclotrimerization reaction. Several key “building blocks” were assembled by a [2+2+2] cycloaddition approach and they have been further expanded by other synthetic transformations to design unusual amino acids and peptides, diphenylalkanes, bis- and trisaryl benzene derivatives, annulated benzocycloalkanes, spirocycles, and spiroox

APA, Harvard, Vancouver, ISO, and other styles

40

Fleming, Steven A., and Susan C. Ward. "Stereocontrolled photochemical [2 + 2] cycloaddition." Tetrahedron Letters 33, no. 8 (1992): 1013–16. http://dx.doi.org/10.1016/s0040-4039(00)91847-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Treutwein, Jonas, and Gerhard Hilt. "Cobalt-Catalyzed [2+2] Cycloaddition." Angewandte Chemie International Edition 47, no. 36 (2008): 6811–13. http://dx.doi.org/10.1002/anie.200801778.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Treutwein, Jonas, and Gerhard Hilt. "Cobalt-katalysierte [2+2]-Cycloaddition." Angewandte Chemie 120, no. 36 (2008): 6916–19. http://dx.doi.org/10.1002/ange.200801778.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Tanaka, K., K. Masutomi, N. Sakiyama, and K. Noguchi. "Rhodium-Catalyzed Asymmetric [2+2+2] Cycloaddition." Synfacts 9, no. 05 (2013): 0575. http://dx.doi.org/10.1055/s-0033-1338458.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Rovis, T., and D. Dalton. "Rhodium-Catalyzed Enantioselective [2+2+2] Cycloaddition." Synfacts 9, no. 09 (2013): 1030. http://dx.doi.org/10.1055/s-0033-1339688.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Meyer, Vera J., Christoph Ascheberg, and Meike Niggemann. "Calcium-Catalyzed Formal [2+2+2] Cycloaddition." Chemistry - A European Journal 21, no. 17 (2015): 6371–74. http://dx.doi.org/10.1002/chem.201500181.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

KANEMATSU, K., N. SUGIMOTO, M. KAWAOKA, S. YEO, and M. SHIRO. "ChemInform Abstract: Competitive Intramolecular (4 + 2)Cycloaddition and (2 + 2) Cycloaddition of Sulfonylallene." ChemInform 23, no. 2 (2010): no. http://dx.doi.org/10.1002/chin.199202197.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Hayashi, Yujiro, and Koichi Narasaka. "ChemInform Abstract: [2 + 2] Cycloaddition Reactions." ChemInform 31, no. 18 (2010): no. http://dx.doi.org/10.1002/chin.200018221.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Braunschweig, Holger, Michael Burzler, Krzysztof Radacki, and Fabian Seeler. "Borylene Metathesis through [2+2] Cycloaddition." Angewandte Chemie International Edition 46, no. 42 (2007): 8071–73. http://dx.doi.org/10.1002/anie.200702982.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Čížková, Martina, Viliam Kolivoška, Ivana Císařová, David Šaman, Lubomír Pospíšil, and Filip Teplý. "Nitrogen heteroaromatic cations by [2+2+2] cycloaddition." Org. Biomol. Chem. 9, no. 2 (2011): 450–62. http://dx.doi.org/10.1039/c0ob00507j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Taylor, Mark S., and Timothy M. Swager. "Triptycenediols by Rhodium-Catalyzed [2 + 2 + 2] Cycloaddition." Organic Letters 9, no. 18 (2007): 3695–97. http://dx.doi.org/10.1021/ol701642j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!