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Dissertations / Theses on the topic 'Stearoyl CoA desaturase'

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Published: 4 June 2021

Last updated: 25 April 2022

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1

Al-Jeryan, Lulwa A. "Characterization of a human stearoyl CoA desaturase gene." Thesis, Glasgow Caledonian University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251231.

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2

Dempsey, Kate E. "Characterisation of a human stearoyl CoA desaturase gene (SCD2)." Thesis, Glasgow Caledonian University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369995.

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3

MacDonald, Marcia Leigh. "Stearoyl-CoA desaturase : role in metabolic syndrome, atherosclerosis and inflammation." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/24653.

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Combination of the risk factors obesity, insulin resistance, dyslipidemia, and hypertension, often described as the "metabolic syndrome," increases the risk of developing diabetes and cardiovascular disease. Stearoyl-coenzyme A desaturase (SCD) activity has been implicated in the metabolic syndrome; however, earlier studies on the beneficial metabolic effects of SCD1 deficiency have been confined to normolipidemic mice, and the role of SCD in the context of atherosclerosis has not been examined. The primary purpose of this thesis was to investigate the effect of decreased SCD activity on susc

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4

lefrevre, pascal. "Regulation genetique de la stearoyl coa desaturase hepatique de poulet." Rennes, Agrocampus Ouest, 1998. http://www.theses.fr/1998NSARIA07.

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L'importance de la stearoyl coa desaturase hepatique (scd1) a ete mise en evidence dans les mecanismes conduisant a la formation du tissu adipeux abdominal du poulet et plusieurs resultats suggerent l'implication du gene lui-meme dans la variabilite du caractere. Dans le but de verifier si l'hypothese d'une regulation essentiellement transcriptionnelle du gene scd1 hepatique etait verifiee ou non chez le poulet, l'etude de la regulation de l'expression de scd1 par des effecteurs hormonaux a ete entreprise. Ensuite, nous avons cherche a identifier des zones genomiques qui pourraient rendre comp

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5

Williams, Catherine Ann. "The role of stearoyl-CoA desaturase in lipid and lipoprotein metabolism." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.537664.

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6

Pinnameneni, Srijan Kumar, and s3083722@student rmit edu au. "Role of stearoyl-CoA desaturase1 in fatty acid-induced insulin resistance." RMIT University. Medical Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20070119.162450.

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Recent investigations suggest that reducing stearoyl CoA desaturase (SCD) 1 expression confers protection against obesity and insulin resistance, whereas others show that increasing SCD1 expression protects cells from lipotoxicity. The overall aim of this thesis was to establish the role of SCD1 expression in fatty acid metabolism and insulin stimulated glucose disposal in skeletal muscle. In vitro and in vivo studies were conducted to investigate the relationship between fatty acid subtype, SCD1 expression and fuel metabolism. The role of fatty acid subtype on fatty acid metabol

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7

Ferdous, Zannatul. "Functional and phenotypic characterization of the stearoyl CoA desaturase gene of Anopheles coluzzii." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/50707.

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Malaria is an infectious disease caused by Plasmodium parasites that are transmitted by the bite of female Anopheles mosquitoes. Successful acquisition and transmission of malaria parasites requires a female mosquito obtaining a blood meal from human hosts. The blood meal, which is rich in protein, is required for egg development. Most of the ingested protein is converted to lipid and stored in the fat body where vitellogenesis takes place. In this process, saturated fatty acids are converted to unsaturated fatty acids by the stearoyl-CoA desaturase (SCD1). Unsaturated fatty acids are also ess

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8

Oatman, Nicole. "Mechanisms regulating cancer cell sensitivity and acquired resistance to Stearoyl-CoA Desaturase inhibition." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1573572568302598.

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9

Dance, Lyndsey Jane Elizabeth. "The genetic and molecular mechanism of CLA formation in cattle : the role of stearoyl-CoA desaturase." Thesis, University of Bristol, 2009. http://hdl.handle.net/1983/21aa24ed-b002-4155-a972-3daaabad56ac.

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10

Feng, Shulan. "Using milk somatic cells to study stearoyl-CoA desaturase enzyme activity in dairy cows." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479368.

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11

Marecak, Dale M. (Dale Michael) Carleton University Dissertation Chemistry. "Investigating the stearoyl COA desaturase system of Saccharomyces cerevisiae by oxidation of sulfide probes." Ottawa, 1994.

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12

Nair, Ajith Sreekantan. "An investigation of the kinetics of stearoyl-CoA desaturase in microsomal membranes from mouse." Thesis, Glasgow Caledonian University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492395.

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Stearoyl-CoA desaturase (SCD) catalyses the rate-limiting step in the biosynthesis of monounsaturated fatty acids by the insertion of a a ^9-cis double bond into acyl-CoA substrates in the presence of NADH and molecular oxygen. Recent work with animals in which expression of the enzyme has been eliminated, suggests a critical role for this enzyme in regulating lipid metabolism and obesity.

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13

Campbell, Davina Elaine. "Identification of Tissue Distribution and Regulation of Bovine Stearoyl-Coa Desaturase by Hormones and Nutrients." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/33967.

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Studies were conducted to investigate the tissue distribution of stearoyl-CoA desaturase-1 (SCD) and the regulation of SCD1 protein expression by dietary fat, insulin, polyunsaturated fatty acids (PUFA), and linoleic acid (cis-9, cis-12 18:2). The first study examined tissue distribution of SCD1 protein in Holstein calves (n=6/diet) fed one of four milk replacer diets for a nine wk period after which they were sacrificed. Milk replacer diets varied in fat content and were formulated and administered as follows: 0.4 kg/d 20% protein, 20% fat (20:20; CON), 0.97 kg/d (28:20; HPLF), 0.97 kg/d (28:

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14

Warensjö, Eva. "Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease : Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat." Doctoral thesis, Uppsala University, Clinical Nutrition and Metabolism, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8312.

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<p>The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. FAs can, however, also be endogenously synthesized by lipogenic enzymes such as elongases and desaturases. Three desaturases are important in humans: Stearoyl-CoA-desaturase (SCD), ∆6-desaturase (D6D) and ∆5-desaturase (D5D) and surrogate measures of desaturase activities can be estimated as product-to-precursor FA ratios.</p><p>In this thesis,

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15

Ren, Jun. "Isolation and molecular characterization of the stearoyl-CoA desaturase (SCD) gene affecting fat deposition in pigs." Doctoral thesis, [S.l.] : [s.n.], 2004. http://webdoc.sub.gwdg.de/diss/2004/ren/ren.pdf.

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16

Henriquez, Rodriguez Eliana. "Assessing the role of the stearoyl-CoA desaturase gene on the fatty acid profile of pork." Doctoral thesis, Universitat de Lleida, 2017. http://hdl.handle.net/10803/403065.

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This PhD dissertation is framed on a line of research aimed at improving pork quality and, particularly, intramuscular fat (IMF) and monounsaturated fatty acid (MUFA) content as two of the main traits affecting nutritional and sensorial pork attributes. Several strategies have been investigated to enhance IMF and MUFA without increasing the rest of fat depots, but one of the most promising approaches is to find out genetic markers specifically associated to them. There is a variant in the promoter of the stearoyl-CoA desaturase (SCD) gene (AY487830:g.2228T>C used as tag single nucleotide polym

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17

Skala, Paul Carleton University Dissertation Chemistry. "Regio- and stereoselective oxidation of sulphur derivatives of fatty acids by the stearoyl coa desaturase system of saccharomyces cerevisiae." Ottawa, 1989.

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18

Lin, Xiaobo. "Stearoyl-COA Desaturase Gene Transcription, mRNA, And Activity In Response To Trans-Vaccenic Acid And Conjugated Linoleic Acid Isomers." Diss., Virginia Tech, 2000. http://hdl.handle.net/10919/39192.

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Studies were conducted to investigate: 1) desaturation of dietary trans-vaccenic acid (TVA, trans11-18:1) to the cis9,trans11-18:2 isomer of conjugated linoleic acid (9/11CLA), 2) effects of two conjugated linoleic acid isomers [9/11CLA or trans10,cis12-18:2 (10/12CLA)] and TVA on enzyme activities and mRNA abundance for lipogenic enzymes, and 3) regulation of stearoyl-CoA desaturase (SCD) gene transcription. In the first study, lactating mice were fed 3% linoleic acid (LA), or 2% LA plus 1% stearic acid (SA), 1% TVA, or 1% CLA mixture. Dietary TVA enriched the 9/11CLA content of carcass, live

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19

Brooks, Matthew Alan. "Carcass characteristics, fatty acids, stearoyl-coa desaturase gene expression and sensory evaluation of calf-fed and yearling-fed angus steers." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-2562.

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20

Jayan, Geetha C. Jr. "Activity and mRNA abundance of enzymes for fatty acid synthesis and desaturation in mammary cell cultures." Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/40519.

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The effect of exogenous unsaturated fatty acids on cellular fatty acid biosynthesis in mammary cells was examined. Under normal situations, even though the diet of a dairy cow contains considerable amounts of unsaturated fatty acids, viz. oleic acid (18:1) and linoleic acid (18:2), the major 18-carbon fatty acid that enters the circulation post-ruminally for delivery to the mammary gland is saturated fatty acid, viz. stearic acid (18:0). This is due to extensive ruminal biohydrogenation of unsaturated fatty acids. Studies have indicated that saturated fatty acids such as 18:0 are enhancers

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21

Alexopoulos, Konstantinos A. Carleton University Dissertation Chemistry. ""The use of fluorinated fatty acids as a mechanistic probe for the fatty acid desaturation by the stearoyl-CoA delta9-desaturase of Saccharomyces cerevisiae." Ottawa, 1994.

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22

Wiman, Josefin. "Investigation of the intra-day variation in stearoyl-CoA-desaturase activity by measuring the product-to-precursor ratios of fatty acids (16:1/16:0 and 18:1/18:0)." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-87728.

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<p>Obesity is today a problem that has reached epidemic proportions. One of the causes of obesity is the over-consumption of energy. Fat is the most energy-dense nutrient, where the quality seems to be more important for the development of the metabolic diseases than the quantity. The fatty acid composition in serum lipid fractions can be used to mirror the dietary fat quality.</p><p>Stearoyl-CoA-desaturase (SCD) is an enzyme that converts saturated to monounsaturated fatty acids. A surrogate measure of SCD activity can be estimated as a fatty acid ratio; 16:1/16:0 (palmitoleic acid/palmitic a

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23

Laura, Martin Maria. "Role of the regulation of cell lipid composition and membrane structure in the antitumor effect of 2-hydroxyoleic acid." Doctoral thesis, Universitat de les Illes Balears, 2011. http://hdl.handle.net/10803/52161.

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El ácido 2-hidroxioleico (2OHOA) es un fármaco antitumoral diseñado para regular la estructura y composición de los lípidos de membrana y la función de importantes proteínas de membrana. El objetivo principal de este trabajo fue estudiar cómo el 2OHOA modula la composición lipídica y la estructura de membrana en las células tumorales. Se observó que el 2OHOA indujo profundas alteraciones en el contenido de fosfolípidos, aumentando el contenido de esfingomielina y disminuyendo el contenido de fosfatidiletanolamina y fosfatidilcolina. Este efecto fue específico contra las células cancerosas, ya

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24

Kgwatalala, Patrick M. 1973. "Genetic polymorphisms in the stearoyl-CoA desaturase1 (SCD1) gene and their influence on the conjugated linoleic acid (CLA) and monounsaturated fatty acids (MUFA) content of milk fat of Canadian Holstein and Jersey cows." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115690.

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Stearoyl-CoA desaturase1 (SCD1) catalyzes the synthesis of conjugated linoleic acid (CLA) and mono-unsaturated fatty acids (MUFA) in the mammary gland of ruminant animals. We hypothesized that single nucleotide polymorphisms (SNPs) in the coding region, 5' and 3' untranslted regions (UTRs) of the SCD1 gene would influence the activity of SCD1 enzyme and consequently account for some within-breed variations in milk CLA and MUFA. Sequence analysis of the coding region of the SCD1 gene of Jerseys and Holsteins revealed c.702A→G, c.762T→C and c.878C→T SNPs in exon 5 in both breeds a

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25

Schmitt, Florent. "Rôle de la stéaroyl-coenzyme A désaturase 1, une enzyme de synthèse des acides gras mono-insaturés, dans un modèle transgénique d’étude de la Sclérose Latérale Amyotrophique." Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAJ085/document.

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La sclérose latérale amyotrophique est une maladie neurodégénérative associée à un dysfonctionnement métabolique. Des altérations du métabolisme des lipides, décrites chez les patients SLA et les animaux modèles, pourraient participer à la mise en place des premières étapes de la maladie. L’objectif de cette thèse était d’étudier le rôle de la stéaroyl-coenzyme A désaturase 1 (SCD1), une enzyme clé du métabolisme des lipides, dans la SLA. En étudiant le profil d’acides gras périphériques dans un modèle de souris SLA, les souris SOD1m, nous avons vu une diminution de l’activité de la SCD1 dès l

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26

Gratraud, Paul. "Caractérisation et inhibition d'étapes clés de la biosynthèse des acides gras chez Plasmodium falciparum et Mycobacterium tuberculosis." Montpellier 2, 2009. http://www.theses.fr/2009MON20013.

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Plasmodium falciparum et Mycobacterium tuberculosis sont deux pathogènes humains, causant respectivement le paludisme et la tuberculose. Les efforts pour combattre ces maladies et leurs ravages se heurtent à une adaptation des pathogènes vis-à-vis de leurs inhibiteurs respectifs. La recherche constante de nouveaux moyens de lutte et de nouvelles cibles d'intérêt pharmacologique sont une priorité dans l'éradication de ces deux organismes. Bien que phylogénétiquement éloignés, l'un étant un eucaryote hématozoaire et l'autre un procaryote, ils partagent des voies métaboliques communes, comme par

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27

Cedernaes, Jonathan. "Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet." Doctoral thesis, Uppsala universitet, Funktionell farmakologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196207.

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The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). The Adhesion GPCR subfamily is known to mediate neural development and immune system functioning, whereas SLCs transport e.g. amino acids, fatty acids (FAs) and drugs over membranes. We aimed to comprehensively characterize Adhesion GPCR and SLC gene expression along the rat GIT. Using qPCR we measured expression of 78 SLCs as well as all 30 Adhesion GPCR

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28

Hussain, Ghulam. "Rôle de la stéaroyl-CoA désaturase-1 dans le maintien de l'activité musculaire : étude d'un modèle lésionel pour la compréhension des altérations métaboliques caractéristiques de la sclérose latérale amyotrophique." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-00921430.

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Les patients SLA et les souris modèles présentent un dysfonctionnement métabolique qui coïncide avec le changement de concentration de différentes espèces lipidiques. Notre hypothèse est qu'un tel dysfonctionnement métabolique au niveau musculaire conduirait aux premiers changements observés dans la SLA. Nous avons montré que l'expression de la stéaroyl-coenzyme A désaturase 1 (SCD1), une enzyme clé de la synthèse des acides gras mono-insaturés à partir des acides gras saturés, est diminuée dans le muscle avant les premiers symptômes moteurs observés chez les souris modèles de SLA. Dans ce mod

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29

Zhang, Haojian. "The Molecular Mechanisms for Maintenance of Cancer Stem Cells in Chronic Myeloid Leukemia: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/614.

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Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder associated with the Philadelphia chromosome (Ph) that arises from a reciprocal translocation between chromosomes 9 and 22, thereby resulting in the formation of the chimeric BCR-ABL oncogene encoding a constitutively activated tyrosine kinase. BCR-ABL tyrosine kinase inhibitors (TKIs) induce a complete hematologic and cytogenetic response in the majority of chronic phrase CML patients. However, TKIs cannot efficiently eradicate leukemia stem cells (LSCs) because of the insensitivity of LSCs to TKIs. Therefore, develop

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30

Sampath, Harini. "The role of stearoyl-CoA desaturase-1 in mediating whole body energy metabolism." 2008. http://www.library.wisc.edu/databases/connect/dissertations.html.

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31

Vallance, Bruce A., Nagat Bissada, Marcia L. E. MacDonald, and Michael R. Hayden. "Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis." 2009. http://hdl.handle.net/2429/12927.

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Absence of stearoyl-CoA desaturase-1 (SCD1) in mice leads to chronic inflammation of the skin and increased susceptibility to atherosclerosis, while also increasing plasma inflammatory markers. A recent report suggested that SCD1 deficiency also increases disease severity in a mouse model of inflammatory bowel disease, induced by dextran sulfate sodium (DSS). However, SCD1-deficient mice are known to consume increased amounts of water, which would also be expected to increase the intake of DSS-treated water. The aim of this study was to determine the effect of SCD1 deficiency on DSS-induced a

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32

Man, Weng Chi. "Topology of stearoyl-CoA desaturase 1 and it's co-localization with acyl-CoA diacylglycerol acyltransferase 2 in endoplasmic reticulum." 2006. http://catalog.hathitrust.org/api/volumes/oclc/84542172.html.

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33

Stryjecki, Carolina. "Saturated and monounsaturated fatty acids differentially regulate adipokine gene expression and are associated with systemic C-Reactive Protein levels." Thesis, 2011. http://hdl.handle.net/10214/2990.

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This thesis investigates the contributions of fatty acids (FA) to adipokine dysregulation and inflammation. Differentiated 3T3-L1 adipocytes were treated with palmitic, stearic, palmitoleic, and oleic acids and changes in adipokine gene expression were measured. Here it was determined that saturated FA (SFA) increased the expression of RANTES and monounsaturated FA (MUFA) decreased the expression of RANTES and IL-6; demonstrating that FA differentially regulate adipokine expression. Relationships between plasma levels of SFA, MUFA and C-reactive protein (CRP) were also identified in a human ob

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34

Mauvoisin, Daniel. "Hormonal regulation of Stearoyl-CoA Desaturase 1 (SCD1) at hepatic level and its role in adipose tissue." Thèse, 2011. http://www.archipel.uqam.ca/4199/1/D2213.pdf.

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La Stearoyl-CoA Désaturase-l (SCD1) est l'enzyme catalysant la synthèse des acides gras monoinsaturés, synthétisant le palmitoléyl-CoA (C16:1) et l'oléoyl-CoA (C18:1) à partir respectivement du palmitoyl-CoA (C16:0) et du stéaroyl-CoA (C18:0). Ces acides gras entrent ensuite dans la composition des triglycérides et des phospholipides membranaires. L'altération de la composition des phospholipides a été impliquée dans de nombreuses maladies incluant l'obésité et le syndrome métabolique associé. SCD1 est fortement exprimée au niveau du foie et du tissu adipeux. Elle est étroitement régulée par d

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35

Ammenwerth, Imke. "Analyse der Expression von Stearoyl-CoA-Desaturase-1 (SCD1) im zentralen und peripheren Nervensystem der Ratte nach Axotomnie /." 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013094562&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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36

Chang, Yeong-Chang, and 張永昌. "Ubiquitous transcriptional factor, YY-1 ,can recognize PRE( preadipocyte repressor element) of SCD2(Stearoyl CoA desaturase 2) gene." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/45102922272711961077.

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碩士<br>國立臺灣大學<br>生化科學研究所<br>81<br>SCD2(Stearoyl CoA desaturase 2)的負調節序列PRE(Preadipocyte repressor element)的序列和一普遍存在之核內因子YY-1的結合序列甚為相似,YY-1對轉錄的調控有時扮演促進子的角色,有時則扮演抑制子的角色 ,端視所涉及的基因以及結合序列而定。目前已經四個不同實驗室分別在研究不同基因的啟動區而找到相同的蛋白質,也就是YY-1,首先是Shenk 等人發現YY-1可以結合到adeno-associa ted P5這個病毒的啟動區以及起動區上面,而且當在一般狀況之下,對於轉錄扮演是抑制的角色,但是這時若是有adenoviruse E1A這個蛋白質出現時 ,則是扮演促進轉錄的角色,接著下來Hariharan等人也發現YY-1具有促進一些核糖體蛋白質基因(rpL30, rpL32)進行轉錄的功能,同時Park以及Atch ison等人發現YY-1具有調節免疫球蛋

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37

Chu, Kiki. "Stearoyl-CoA desaturase 1 : transcriptional regulation by liver X receptor and its role in very low-density lipoprotein metabolism /." 2008. http://www.library.wisc.edu/databases/connect/dissertations.html.

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38

Ren, Jun [Verfasser]. "Isolation and molecular characterization of the stearoyl-CoA desaturase (SCD) gene affecting fat deposition in pigs / by Jun Ren." 2004. http://d-nb.info/97081352X/34.

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39

Shen, Chu-Fu, and 沈舉茀. "Effects of high-fat-high-fructose diets with different types of oil on the cognitive performance and brain stearoyl-coA desaturase in rats." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/61301335461146386404.

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碩士<br>臺北醫學大學<br>保健營養學研究所<br>101<br>Stearoyl-CoA desaturase (SCD), one of the lipid synthesizing enzymes, plays an important role in hyperglycemia. Previous studies found that SCD expression increased in the brains of Alzheimer’s disease patients, and the expression of SCD was negatively correlated with cognitive score. The purpose of the present study was to investigate the effect of high fat high fructose diet (HFHF) on blood insulin resistance, brain cognitive impairment, SCD expression in rats. Wistar rats were 32 male, 6 weeks old and divided into 3 groups: control group (n=8), soybean oil

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40

Clark, Laura Ashley. "The Effect of Mutations in Stearoyl CoA Desaturase Gene and Fatty Acid Synthase on Milk Composition and Fatty Acid Profile in Milk Fat of Dairy Cows." Master's thesis, 2009. http://hdl.handle.net/10048/724.

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The effects of diet on milk fatty acid profile, including conjugated linoleic acid (CLA) have been well documented, however, there is limited information on the interaction of diet with genetics. The objective of this research was to determine the effect of single nucleotide polymorphisms (SNP) in the stearoyl CoA desaturase (SCD) gene on the ability to produce CLA in dairy cows fed low and high fat diets. The secondary objective was to determine the effect of a SNP in fatty acid synthase (FASN) on milk yield and composition. There was no effect of SCD genotype on CLA concentration, however

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41

Gomez, Francisco Enrique. "Differential regulation of stearoyl-CoA desaturase expression and activity by thiazolidinediones, steroid hormones and fatty acid analogs using the mouse 3T3-L1 preadipocyte cell line as model system." 2003. http://www.library.wisc.edu/databases/connect/dissertations.html.

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