Log in

Relevant bibliographies by topics / Stearoyl CoA desaturase / Journal articles

To see the other types of publications on this topic, follow the link: Stearoyl CoA desaturase.

Journal articles on the topic 'Stearoyl CoA desaturase'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 April 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Stearoyl CoA desaturase.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Oatman, Nicole, Julie Reisz, Angelo D’Alessandro, and Biplab Dasgupta. "TAMI-55. THE EVOLUTIONARY ENIGMA OF FATTY ACID DESATURATION IN GLIOBLASTOMA." Neuro-Oncology 22, Supplement_2 (November 2020): ii225. http://dx.doi.org/10.1093/neuonc/noaa215.942.

Full text

Abstract:

Abstract Fatty acid desaturation is an enzymatic reaction in which a double bond is introduced into an acyl chain. Of the four functionally distinct desaturase subfamilies, the First Desaturase Family of enzymes introduce the first double bond into a saturated fatty acid, resulting in the synthesis of monounsaturated fatty acids (MUFA). MUFA are essential components of membrane and storage lipids and exert a profound influence on the fluidity of biological membranes. A disequilibrium in saturated to unsaturated fatty acid ratio alters cell growth, differentiation and response to external stimu

APA, Harvard, Vancouver, ISO, and other styles

2

Oatman, Nicole, and Biplab Dasgupta. "DDRE-15. THE EVOLUTIONARY ENIGMA OF FATTY ACID DESATURATION IN GLIOBLASTOMA." Neuro-Oncology Advances 3, Supplement_1 (March 1, 2021): i9. http://dx.doi.org/10.1093/noajnl/vdab024.037.

Full text

Abstract:

Abstract Fatty acid desaturation is an enzymatic reaction in which a double bond is introduced into an acyl chain. Of the four functionally distinct desaturase subfamilies, the First Desaturase Family of enzymes introduce the first double bond into a saturated fatty acid, resulting in the synthesis of monounsaturated fatty acids (MUFA). MUFA are essential components of membrane and storage lipids and exert a profound influence on the fluidity of biological membranes. A disequilibrium in saturated to unsaturated fatty acid ratio alters cell growth, differentiation and response to external stimu

APA, Harvard, Vancouver, ISO, and other styles

3

Kawashima, Y., N. Uy-Yu, and H. Kozuka. "Sex-related differences in the enhancing effects of perfluoro-octanoic acid on stearoyl-CoA desaturase and its influence on the acyl composition of phospholipid in rat liver. Comparison with clofibric acid and tiadenol." Biochemical Journal 263, no. 3 (November 1, 1989): 897–904. http://dx.doi.org/10.1042/bj2630897.

Full text

Abstract:

The effects of the peroxisome proliferators clofibric acid (p-chlorophenoxyisobutyric acid), tiadenol [2,2′-(decamethylenedithio)diethanol] and perfluoro-octanoic acid (PFOA) on hepatic stearoyl-CoA desaturation in male and female rats were compared. Treatment of male rats with the three peroxisome proliferators increased markedly the activity of stearoyl-CoA desaturase. Administration of clofibric acid or tiadenol to female rats increased greatly the hepatic activity of stearoyl-CoA desaturase, the extent of the increases being slightly less pronounced than those of male rats. In contrast wit

APA, Harvard, Vancouver, ISO, and other styles

4

Kikuchi, Kohtaro, and Hidekazu Tsukamoto. "Stearoyl-CoA desaturase and tumorigenesis." Chemico-Biological Interactions 316 (January 2020): 108917. http://dx.doi.org/10.1016/j.cbi.2019.108917.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Lu, He, Xin Qin, Jing Zhang, Shuang Zhang, Yu Zhu, and Wei Hua Wu. "Molecular target analysis of stearoyl-CoA desaturase genes of protozoan parasites." Acta Parasitologica 63, no. 1 (March 26, 2018): 48–54. http://dx.doi.org/10.1515/ap-2018-0006.

Full text

Abstract:

AbstractProtozoan parasites can synthesize polyunsaturated fatty acids. They possess stearoyl-CoA desaturase to convert stearate into oleate and linoleate. Stearoyl-CoA desaturase are the key enzymes required for the synthesis of unsaturated fatty acids. It seems attractive to evaluate the possibility of using unsaturated fatty acid biosynthesis pathways as drug targets. In this study, the authors investigate codon usage bias, base composition variations and protein sequence in ten available complete stearoyl-CoA desaturase gene sequences fromToxoplasma gondii,Neospora caninumetc. The results

APA, Harvard, Vancouver, ISO, and other styles

6

Hao, Pan, Xia Cui, Jing Liu, Muzi Li, Yong Fu, and Qun Liu. "Identification and characterization of stearoyl-CoA desaturase in Toxoplasma gondii." Acta Biochimica et Biophysica Sinica 51, no. 6 (May 29, 2019): 615–26. http://dx.doi.org/10.1093/abbs/gmz040.

Full text

Abstract:

Abstract Few information of the function of stearoyl-coenzyme A (CoA) desaturase (SCD) in apicomplaxan parasite has been obtained. In this study, we retrieved a putative fatty acyl-CoA desaturase (TGGT1_238950) by a protein alignment with Plasmodium falciparum SCD in ToxoDB. A typical Δ9-desaturase domain was revealed in this protein. The putative desaturase was tagged with HA endogenously in Toxoplasma gondii, and the endoplasmic reticulum localization of the putative desaturase was revealed, which was consistent with the fatty acid desaturases in other organisms. Therefore, the TGGT1_238950

APA, Harvard, Vancouver, ISO, and other styles

7

Ntambi, James M., Makoto Miyazaki, and Agnieszka Dobrzyn. "Regulation of stearoyl-CoA desaturase expression." Lipids 39, no. 11 (November 2004): 1061–65. http://dx.doi.org/10.1007/s11745-004-1331-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Ntambi, James M., Youngjin Choi, Yeonhwa Park, Jeffrey M. Peters, and Michael W. Pariza. "Effects of Conjugated Linoleic Acid (CLA) on Immune Responses, Body Composition and Stearoyl-CoA Desaturase." Canadian Journal of Applied Physiology 27, no. 6 (December 1, 2002): 617–27. http://dx.doi.org/10.1139/h02-036.

Full text

Abstract:

Conjugated linoleic acid (CLA) has shown a wide range of biologically beneficial effects; reduction of incidence and severity of animal carcinogenesis, reduction of the adverse effects of immune stimulation, reduction of severity of atherosclerosis, growth promotion in young rats, and modulation of stearoyl-CoA desaturase (SCD). One of the most interesting aspects of CLA is its ability to reduce body fat while enhancing lean body mass which is associated with the trans-10,cis-12 isomer of CLA. The effects of CLA are unique characteristics that have not been observed with other polyunsaturated

APA, Harvard, Vancouver, ISO, and other styles

9

Sæther, Thomas, Thien N. Tran, Helge Rootwelt, Bjørn O. Christophersen та Trine B. Haugen. "Expression and Regulation of Δ5-Desaturase, Δ6-Desaturase, Stearoyl-Coenzyme A (CoA) Desaturase 1, and Stearoyl-CoA Desaturase 2 in Rat Testis". Biology of Reproduction 69, № 1 (1 липня 2003): 117–24. http://dx.doi.org/10.1095/biolreprod.102.014035.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Murphy, D. J., I. E. Woodrow, and K. D. Mukherjee. "Substrate specificities of the enzymes of the oleate desaturase system from photosynthetic tissue." Biochemical Journal 225, no. 1 (January 1, 1985): 267–70. http://dx.doi.org/10.1042/bj2250267.

Full text

Abstract:

In the microsomal fraction from young pea (Pisum sativum L.) leaves, the oleoyl moieties from oleoyl-CoA are principally transferred to the sn-2 position of phosphatidylcholine by oleoyl-CoA:1-acyl-lysophosphatidylcholine acyltransferase. The major product of this acyl transfer is 1-palmitoyl(stearoyl)-2-oleoyl phosphatidylcholine. The 1-palmitoyl(stearoyl)-2-oleoyl phosphatidylcholine is subsequently converted into 1-palmitoyl(stearoyl)-2-linoleoyl phosphatidylcholine by the oleate desaturase complex without equilibrating with the bulk membrane phosphatidylcholine pool. Hence, both the acyl t

APA, Harvard, Vancouver, ISO, and other styles

11

Kucharski, Mirosław, and Urszula Kaczor. "Stearoyl-CoA desaturase – the lipid metabolism regulator." Postępy Higieny i Medycyny Doświadczalnej 68 (March 27, 2014): 334–42. http://dx.doi.org/10.5604/17322693.1095856.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Hodson, Leanne, and Barbara A. Fielding. "Stearoyl-CoA desaturase: rogue or innocent bystander?" Progress in Lipid Research 52, no. 1 (January 2013): 15–42. http://dx.doi.org/10.1016/j.plipres.2012.08.002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Tebbey, Paul W., and Thomas M. Buttke. "Stearoyl-CoA desaturase gene expression in lymphocytes." Biochemical and Biophysical Research Communications 186, no. 1 (July 1992): 531–36. http://dx.doi.org/10.1016/s0006-291x(05)80840-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Ntambi, James M., and Makoto Miyazaki. "Recent insights into stearoyl-CoA desaturase-1." Current Opinion in Lipidology 14, no. 3 (June 2003): 255–61. http://dx.doi.org/10.1097/00041433-200306000-00005.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Ntambi, James M. "The regulation of stearoyl-CoA desaturase (SCD)." Progress in Lipid Research 34, no. 2 (January 1995): 139–50. http://dx.doi.org/10.1016/0163-7827(94)00010-j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Cai, Yuanheng, Xiao-Hong Yu, Jin Chai, Chang-Jun Liu та John Shanklin. "A conserved evolutionary mechanism permits Δ9 desaturation of very-long-chain fatty acyl lipids". Journal of Biological Chemistry 295, № 32 (11 червня 2020): 11337–45. http://dx.doi.org/10.1074/jbc.ra120.014258.

Full text

Abstract:

Δ9 fatty acyl desaturases introduce a cis–double bond between C9 and C10 of saturated fatty acyl chains. From the crystal structure of the mouse stearoyl-CoA desaturase (mSCD1) it was proposed that Tyr-104, a surface residue located at the distal end of the fatty acyl binding pocket plays a key role in specifying 18C selectivity. We created mSCD1-Y104G to test the hypothesis that eliminating this bulky side chain would create an opening and permit the substrate's methyl end to protrude through the enzyme into the lipid bilayer, facilitating the desaturation of very-long-chain (VLC) substrates.

APA, Harvard, Vancouver, ISO, and other styles

17

O’Neill, Lucas M., Chang-An Guo, Fang Ding, Yar Xin Phang, Zhaojin Liu, Sohel Shamsuzzaman, and James M. Ntambi. "Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease." International Journal of Molecular Sciences 21, no. 22 (November 16, 2020): 8619. http://dx.doi.org/10.3390/ijms21228619.

Full text

Abstract:

Stearoyl-CoA Desaturase-2 (SCD2) is a member of the Stearoyl-CoA Desaturase (SCD) family of enzymes that catalyze the rate-limiting step in monounsaturated fatty acid (MUFA) synthesis. The MUFAs palmitoleoyl-CoA (16:1n7) and oleoyl-CoA (18:1n9) are the major products of SCD2. Palmitoleoyl-CoA and oleoyl-CoA have various roles, from being a source of energy to signaling molecules. Under normal feeding conditions, SCD2 is ubiquitously expressed and is the predominant SCD isoform in the brain. However, obesogenic diets highly induce SCD2 in adipose tissue, lung, and kidney. Here we provide a comp

APA, Harvard, Vancouver, ISO, and other styles

18

Paton, Chad M., and James M. Ntambi. "Biochemical and physiological function of stearoyl-CoA desaturase." American Journal of Physiology-Endocrinology and Metabolism 297, no. 1 (July 2009): E28—E37. http://dx.doi.org/10.1152/ajpendo.90897.2008.

Full text

Abstract:

A key and highly regulated enzyme that is required for the biosynthesis of monounsaturated fatty acids is stearoyl-CoA desaturase (SCD), which catalyzes the D9- cis desaturation of a range of fatty acyl-CoA substrates. The preferred substrates are palmitoyl- and stearoyl-CoA, which are converted into palmitoleoyl- and oleoyl-CoA respectively. Oleate is the most abundant monounsaturated fatty acid in dietary fat and is therefore readily available. Studies of mice that have a naturally occurring mutation in the SCD-1 gene isoform as well as a mouse model with a targeted disruption of the SCD gen

APA, Harvard, Vancouver, ISO, and other styles

19

Cohen, Paul, James M. Ntambi, and Jeffrey M. Friedman. "Stearoyl-CoA Desaturase-1 and the Metabolic Syndrome." Current Drug Targets - Immune, Endocrine & Metabolic Disorders 3, no. 4 (December 1, 2003): 271–80. http://dx.doi.org/10.2174/1568008033340117.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Williams, Noelle S., Stephen Gonzales, Jacinth Naidoo, Giomar Rivera-Cancel, Sukesh Voruganti, Prema Mallipeddi, Panayotis C. Theodoropoulos, et al. "Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase." Journal of Medicinal Chemistry 63, no. 17 (August 5, 2020): 9773–86. http://dx.doi.org/10.1021/acs.jmedchem.0c00899.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Attie, Alan D., Matthew T. Flowers, Jessica B. Flowers, Albert K. Groen, Folkert Kuipers, and James M. Ntambi. "Stearoyl-CoA Desaturase Deficiency, Hypercholesterolemia, Cholestasis, and Diabetes." Nutrition Reviews 65 (June 28, 2008): S35—S38. http://dx.doi.org/10.1111/j.1753-4887.2007.tb00326.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Attie, Alan D., Matthew T. Flowers, Jessica B. Flowers, Albert K. Groen, Folkert Kuipers, and James M. Ntambi. "Stearoyl-CoA Desaturase Deficiency, Hypercholesterolemia, Cholestasis, and Diabetes." Nutrition Reviews 65, no. 6 (June 1, 2007): 35–38. http://dx.doi.org/10.1301/nr.2007.jun.s35-s38.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Man, Weng Chi, Makoto Miyazaki, Kiki Chu, and James M. Ntambi. "Membrane Topology of Mouse Stearoyl-CoA Desaturase 1." Journal of Biological Chemistry 281, no. 2 (November 7, 2005): 1251–60. http://dx.doi.org/10.1074/jbc.m508733200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Liu, Gang. "Stearoyl-CoA desaturase inhibitors: update on patented compounds." Expert Opinion on Therapeutic Patents 19, no. 9 (August 19, 2009): 1169–91. http://dx.doi.org/10.1517/13543770903061311.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Vincent, Benjamin M., Daniel F. Tardiff, Jeff S. Piotrowski, Rebecca Aron, Matthew C. Lucas, Chee Yeun Chung, Helene Bacherman та ін. "Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity". Cell Reports 25, № 10 (грудень 2018): 2742–54. http://dx.doi.org/10.1016/j.celrep.2018.11.028.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Kamal, Shagufta, Ayesha Saleem, Saima Rehman, Ismat Bibi, and Hafiz M. N. Iqbal. "Protein engineering: Regulatory perspectives of stearoyl CoA desaturase." International Journal of Biological Macromolecules 114 (July 2018): 692–99. http://dx.doi.org/10.1016/j.ijbiomac.2018.03.171.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Li, Chun Sing, Liette Belair, Jocelyne Guay, Renata Murgasva, Wayne Sturkenboom, Yeeman K. Ramtohul, Lei Zhang, and Zheng Huang. "Thiazole analog as stearoyl-CoA desaturase 1 inhibitor." Bioorganic & Medicinal Chemistry Letters 19, no. 17 (September 2009): 5214–17. http://dx.doi.org/10.1016/j.bmcl.2009.07.015.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Koeberle, Andreas, Konstantin Löser, and Maria Thürmer. "Stearoyl-CoA desaturase-1 and adaptive stress signaling." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1861, no. 11 (November 2016): 1719–26. http://dx.doi.org/10.1016/j.bbalip.2016.08.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Shen, Jiemin, Gang Wu, Ah-Lim Tsai, and Ming Zhou. "Structure and Function of Mammalian Stearoyl-COA Desaturase." Biophysical Journal 114, no. 3 (February 2018): 426a. http://dx.doi.org/10.1016/j.bpj.2017.11.2361.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Petroff, Anna B., Rebecca L. Weir, Charles R. Yates, Joseph D. Ng, and Jerome Baudry. "Sequential Dynamics of Stearoyl-CoA Desaturase-1(SCD1)/Ligand Binding and Unbinding Mechanism: A Computational Study." Biomolecules 11, no. 10 (September 30, 2021): 1435. http://dx.doi.org/10.3390/biom11101435.

Full text

Abstract:

Stearoyl-CoA desaturase-1 (SCD1 or delta-9 desaturase, D9D) is a key metabolic protein that modulates cellular inflammation and stress, but overactivity of SCD1 is associated with diseases, including cancer and metabolic syndrome. This transmembrane endoplasmic reticulum protein converts saturated fatty acids into monounsaturated fatty acids, primarily stearoyl-CoA into oleoyl-CoA, which are critical products for energy metabolism and membrane composition. The present computational molecular dynamics study characterizes the molecular dynamics of SCD1 with substrate, product, and as an apoprote

APA, Harvard, Vancouver, ISO, and other styles

31

Miyazaki, Makoto, Francisco Enrique Gomez та James M. Ntambi. "Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Δ6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse". Journal of Lipid Research 43, № 12 (16 вересня 2002): 2146–54. http://dx.doi.org/10.1194/jlr.m200271-jlr200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

NAKASHIMA, Shigeru, Yutong ZHAO та Yoshinori NOZAWA. "Molecular cloning of Δ9 fatty acid desaturase from the protozoan Tetrahymena thermophila and its mRNA expression during thermal membrane adaptation". Biochemical Journal 317, № 1 (1 липня 1996): 29–34. http://dx.doi.org/10.1042/bj3170029.

Full text

Abstract:

In response to a decrease in its growth temperature, the protozoan Tetrahymena is known to increase the level of unsaturated fatty acids in its membrane phospholipids so as to maintain the correct physical state (fluidity) of the membranes. In this organism, synthesis of unsaturated fatty acids is initiated by Δ9 acyl-CoA desaturase. Our previous studies have shown that, during cold adaptation, the activity of microsomal palmitoyl- and stearoyl-CoA desaturase increases, reaching a maximal level at 2 h after a temperature down-shift to 15 °C. Two hypotheses have been proposed to explain this in

APA, Harvard, Vancouver, ISO, and other styles

33

Milanesi, E., L. Nicoloso, and P. Crepaldi. "Stearoyl CoA desaturase gene polymorphism in Italian cattle breeds." Italian Journal of Animal Science 6, sup1 (January 2007): 167. http://dx.doi.org/10.4081/ijas.2007.1s.167.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Moioli, B., L. Orrù, G. Catillo, G. B. Congiu, and F. Napolitano. "Partial sequencing of Stearoyl-CoA desaturase gene in buffalo." Italian Journal of Animal Science 4, sup2 (January 2005): 25–27. http://dx.doi.org/10.4081/ijas.2005.2s.25.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Dobrzyn, Pawel, Tomasz Bednarski, and Agnieszka Dobrzyn. "Metabolic reprogramming of the heart through stearoyl-CoA desaturase." Progress in Lipid Research 57 (January 2015): 1–12. http://dx.doi.org/10.1016/j.plipres.2014.11.003.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Savino, Angela Maria, Orianne Olivares, Shani Barel, Lev Yakimov, Ifat Geron, Hila Fishman, Inbal Mor, et al. "Stearoyl-CoA Desaturase (SCD) Enhances Central Nervous System Leukemia." Blood 132, Supplement 1 (November 29, 2018): 389. http://dx.doi.org/10.1182/blood-2018-99-114749.

Full text

Abstract:

Abstract Background: Central nervous system (CNS) involvement by acute lymphoblastic leukemia (ALL) is a major clinical concern. Leukemic cells can be found in the CNS at diagnosis (1-2%) or, more frequently, at relapse (30%). Very little is known about the pathogenesis and therefore there are no targeted therapies. Prophylactic CNS-directed conventional intrathecal chemotherapy or irradiation are required for relapse-free survival. However, they are associated with substantial rates of short and long term toxicity. Therefore, elucidation of molecular mechanisms and pathways mediating leukemia

APA, Harvard, Vancouver, ISO, and other styles

37

Dobrzyn, Agnieszka, and Pawel Dobrzyn. "Inhibition of stearoyl-CoA desaturase by cyclic amine derivatives." Expert Opinion on Therapeutic Patents 18, no. 4 (April 2008): 457–60. http://dx.doi.org/10.1517/13543776.18.4.457.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Bai, Yonghong, Jason G. McCoy, Elena J. Levin, Pablo Sobrado, Kanagalaghatta R. Rajashankar, Brian G. Fox, and Ming Zhou. "X-ray structure of a mammalian stearoyl-CoA desaturase." Nature 524, no. 7564 (June 22, 2015): 252–56. http://dx.doi.org/10.1038/nature14549.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

NERGİS, Hazniye, Seyrani KONCAGÜL, and Selahaddin KİRAZ. "Hereford ırkı sığırlarda stearoyl-CoA desaturase (SCD) gen polimorfizmi." Harran Tarım ve Gıda Bilimleri Dergisi 23, no. 2 (June 18, 2019): 247–53. http://dx.doi.org/10.29050/harranziraat.487490.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Sampath, Harini, and James M. Ntambi. "Role of stearoyl-CoA desaturase in human metabolic disease." Future Lipidology 3, no. 2 (April 2008): 163–73. http://dx.doi.org/10.2217/17460875.3.2.163.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

UMEKI, Shigenobu, and Yoshiniri NOZAWA. "Effect of Local Anesthetics on Stearoyl-CoA Desaturase ofTetrahymenaMicrosomes." Biological Chemistry Hoppe-Seyler 367, no. 1 (January 1986): 61–66. http://dx.doi.org/10.1515/bchm3.1986.367.1.61.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Fenner, Annette. "Stearoyl-CoA desaturase: a novel therapeutic target for RCC." Nature Reviews Urology 10, no. 7 (May 21, 2013): 370. http://dx.doi.org/10.1038/nrurol.2013.116.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Zhang, Chun-Lei, Xue-Yuan Gao, Ru-Ying Shao, Yan-Hong Wang, Xing-Tang Fang, and Hong Chen. "Stearoyl-CoA Desaturase (SCD) Gene Polymorphism in Goat Breeds." Biochemical Genetics 48, no. 9-10 (July 14, 2010): 822–28. http://dx.doi.org/10.1007/s10528-010-9363-y.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Koltun, Dmitry O., Natalya I. Vasilevich, Eric Q. Parkhill, Andrei I. Glushkov, Timur M. Zilbershtein, Elena I. Mayboroda, Melanie A. Boze, et al. "Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors." Bioorganic & Medicinal Chemistry Letters 19, no. 11 (June 2009): 3050–53. http://dx.doi.org/10.1016/j.bmcl.2009.04.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Wang, Jian, Lan Yu, He Wang, Yunling Gao, James P. Schrementi, Regina K. Porter, David A. Yurek, et al. "Identification and Characterization of Hamster Stearoyl-CoA Desaturase Isoforms." Lipids 43, no. 3 (December 15, 2007): 197–205. http://dx.doi.org/10.1007/s11745-007-3139-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Liu, Xueqing, Makoto Miyazaki, Matthew T. Flowers, Harini Sampath, Minghui Zhao, Kiki Chu, Chad M. Paton, Diane Seohee Joo, and James M. Ntambi. "Loss of Stearoyl-CoA Desaturase-1 Attenuates Adipocyte Inflammation." Arteriosclerosis, Thrombosis, and Vascular Biology 30, no. 1 (January 2010): 31–38. http://dx.doi.org/10.1161/atvbaha.109.195636.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Liu, Lulu, Yu Wang, Xiaojuan Liang, Xiao Wu, Jiali Liu, Shulin Yang, Cong Tao, et al. "Stearoyl-CoA Desaturase Is Essential for Porcine Adipocyte Differentiation." International Journal of Molecular Sciences 21, no. 7 (April 1, 2020): 2446. http://dx.doi.org/10.3390/ijms21072446.

Full text

Abstract:

Fat deposition, which influences pork production, meat quality and growth efficiency, is an economically important trait in pigs. Numerous studies have demonstrated that stearoyl-CoA desaturase (SCD), a key enzyme that catalyzes the conversion of saturated fatty acids into monounsaturated fatty acids, is associated with fatty acid composition in pigs. As SCD was observed to be significantly induced in 3T3-L1 preadipocytes differentiation, we hypothesized that it plays a role in porcine adipocyte differentiation and fat deposition. In this study, we revealed that SCD is highly expressed in adip

APA, Harvard, Vancouver, ISO, and other styles

48

ZHANG, Lin, Lan GE, Tai TRAN, Kurt STENN, and Stephen M. PROUTY. "Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element." Biochemical Journal 357, no. 1 (June 25, 2001): 183–93. http://dx.doi.org/10.1042/bj3570183.

Full text

Abstract:

Stearoyl-CoA desaturase is the rate-limiting enzyme in the production of mono-unsaturated fatty acids. We have recently cloned and characterized the human Scd cDNA and SCD (the stearoyl-CoA desaturase structural gene) on chromosome 10, as well as the non-transcribed pseudogene on chromosome 17. In order to further define SCD regulation and function, we have isolated and characterized the promoter of the structural gene. Screening of chromosome-10-specific libraries resulted in the isolation of 4.1kb of SCD sequence upstream of the translation start site. Binding sites for transcription factors

APA, Harvard, Vancouver, ISO, and other styles

49

Li, Weihua, Huimin Bai, Shiping Liu, Dongyan Cao, Hongying Wu, Keng Shen, Yanhong Tai, and Jiaxin Yang. "Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression." Oncotarget 9, no. 15 (January 24, 2018): 12064–78. http://dx.doi.org/10.18632/oncotarget.24304.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Dobrzyn, A. "The Role of Stearoyl-CoA Desaturase in Body Weight Regulation." Trends in Cardiovascular Medicine 14, no. 2 (February 2004): 77–81. http://dx.doi.org/10.1016/j.tcm.2003.12.005.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!