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1

Sixtus, Selepe Tsepang, and Manoharan Karuppiah Pillai. "Evaluation of antioxidant activity of extracts from Leucosidea sericea." Herba Polonica 68, no. 1 (2022): 10–18. http://dx.doi.org/10.2478/hepo-2022-0001.

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Summary Introduction: Leucosidea sericea finds applications in the treatment of herpes and HIV. Objective: The aim of the current study was to evaluate the antioxidant activity and determine the total flavonoid contents (TFCs) and total phenolic contents (TPCs) of hexane, chloroform, ethyl acetate, acetone and methanol crude extracts obtained from leaves and stem-bark of L. sericea. Methods: Maceration and hot solvent extraction methods were used to obtain various crude extracts. DPPH and ferric reducing power assays were used to evaluate the antioxidant activity. Colorimetric aluminium chlori
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Kariuki, Ibrahim Waweru, Mathew Ngugi, and John Maingi. "Qualitative phytochemical screening and in vitro antioxidant activities of aqueous extracts of Rhaphiolepis bibas (Lour.) Galasso & Banfi." Acta Marisiensis - Seria Medica 70, no. 3 (2024): 175–85. http://dx.doi.org/10.2478/amma-2024-0022.

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Abstract Reactive oxygen species causes harm to cell membranes and biomolecules, wherefore chronic diseases develop. Antioxidants scavenge such free radicals combating oxidative stress. This research aimed to determine the antioxidant potential of the aqueous stem bark, root and leaf extracts of Rhaphiolepis bibas against standards. DPPH radical scavenging activity was high from th stem bark extract at 72.33% with root extract at 65.85% and leaf extract at 55.91%, while ascorbic acid scavenged 89.53% of DPPH radicals. The leaf extract had the highest H2O2 scavenging activity of 91.92% with ste
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Udaya, Shreya, Nishith Babu, Dechamma Pandyanda Nanjappa, Krithika Kalladka, Gunimala Chakraborty, and Anirban Chakraborty. "Evaluation of Toxicity and Antioxidant Property of Cassia fistula Stem Bark Extracts in Zebrafish." Journal of Health and Allied Sciences NU 10, no. 03 (2020): 109–15. http://dx.doi.org/10.1055/s-0040-1715995.

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Abstract Objective This study was aimed at evaluating the toxicity and the antioxidant property of Cassia fistula stem bark extracts in zebrafish. Materials and Methods Crude aqueous and ethanol extracts of C. fistula stem bark were obtained following a standard solvent-based extraction method. The toxicity of these extracts on zebrafish embryonic development was determined and the LC50 values were calculated. Finally, the antioxidant property of C. fistula stem bark extracts was determined in arsenic-induced oxidative stress models of zebrafish. Results The aqueous extract of C. fistula stem
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Rosa, D., B. Elya, M. Hanafi та A. Khatib. "In vitro and molecular docking of α-Glucosidase inhibitor potency from Artabotrys suaveolens leaf and stem bark". IOP Conference Series: Earth and Environmental Science 1116, № 1 (2022): 012007. http://dx.doi.org/10.1088/1755-1315/1116/1/012007.

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Abstract Artabotrys suaveolens is one of the species from Artabotrys genus, one of the largest genus from Annonaceae family. This plant has been used traditionally to treat several diseases and also as emmenagogue. This research was aimed to explore the potency of Artabotrys suaveolens`s leaf and stem bark extracts as α-glucosidase inhibitor using in vitro and molecular docking techniques. It was found that IC50 of α-glucosidase inhibition activity of leaf extract was 48.18±0.16 ppm while the one of stem bark extract was 44.99±0.35 ppm. Besides that, it was also found that IC50 of DPPH free ra
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Mondal, Omar Ali, KAMSH Mondal, and Nurul Islam. "Antifungal Potentials of Derris indica (LAM.) Bennet Extractives." Journal of Life and Earth Science 7 (August 22, 2014): 61–65. http://dx.doi.org/10.3329/jles.v7i0.20122.

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Antifungal activity of the D. indica (Lam.) Bennet. extractives collected in CHCl3 and methanol were tested against seven pathogenic fungi F. vasinfectum, A. fumigatus, A. niger, A. flavus, Mucor sp., C. albicans and P. notatum at concentrations of 50 and 200 ?g/disc along with a standard Nystatin (50 ?g/disc). The fruit shell extract showed activity index against C. albicans and P. notatum. The leaf and the root bark extracts were responsive on A. fumigatus, C. albicans, P. notatum and F. vasinfectum. For the root wood extract F. vasinfectum, A. fumigatus,, C. albicans were responsive. For th
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Cholifah, Nurul, Ahmad Ridhay, Pasjan Satrimafitrah, Ruslan, and Hardi Ys. "Aktivitas Antibakteri Ekstrak Metanol dari Kulit Batang Kelor (Moringa oleifera Lam.) Terhadap Bakteri Staphylococcus aureus dan Escherichia coli." KOVALEN: Jurnal Riset Kimia 6, no. 1 (2020): 34–38. http://dx.doi.org/10.22487/kovalen.2020.v6.i1.12854.

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Antibacterial activity of Moringa oleifera Lam. stem bark has been tested against Staphylococcus aureus and Escherichia coli. The extraction of Moringa oleifera Lam. stem bark was used maceration method with methanol solvent and has obtained extract yield of 6.1%. The antibacterial activity test of Moringa oleifera stem bark extracts used a well diffusion method. The concentration of Moringa oleifera stem bark extract was varied to four concentrations of 1% 2% 3% 4% (w/v). The inhibition zone of methanol extract of Moringa oleifera stem bark against Staphylococcus aureus at extract concentrati
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Hasanuzzaman, M., W. Islam, and MB Islam. "Phytochemical screening of Syzygium cumini (L.) extracts in different solvents." Journal of Bio-Science 24 (July 18, 2018): 11–18. http://dx.doi.org/10.3329/jbs.v24i0.37483.

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Phytochemical screening of the secondary metabolites was performed with acetone, chloroform, methanol and n-hexane extracts of the leaves, roots, stem bark and seeds of the plant Syzygium cumini (Linn.) and were detected using various tests for identifying the isolated components. Acetone extract of the leaves showed the presence glycosides, phenols, proteins, resins and saponins while the stem bark extract showed the presence of alkaloids, flavonoids, glycosides, phenols, proteins, resins and saponins. All the above constituents except saponins were detected in the root extract. The seed extr
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Fadhli, Haiyul, Nofri Hendri Sandi, and Ainun Nurain Nurdin. "AKTIVITAS INHIBISI ENZIM ALFA-GLUKOSIDASE DARI EKSTRAK KULIT BATANG BUNGA KUPU-KUPU (Bauhinia semibifida Roxb) SECARA IN VITRO." Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 6, no. 2 (2021): 223–31. http://dx.doi.org/10.36387/jiis.v6i2.701.

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Research on the activity of ?-glucosidase inhibition of Bunga Kupu-Kupu stem bark extract (Bauhinia semibifida Roxb) has been carried out in vitro. This study aims to determine the inhibitory activity of the extracts of B. semibifida Roxb. stem bark against the ?-glucosidase enzyme in vitro. Testing the inhibitory activity of the ?-glucosidase enzyme using extracts of n-hexane, ethyl acetate, and methanol from the stem bark of the Bunga Kupu-Kupu and the Akarbose as a positive control. In vitro testing was carried out using a microplate reader instrument with a wavelength of 410 nm. The result
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9

Pillai, M. K., R. P. Matamane, and S. B. Mekbib. "Antimicrobial activities of extracts from Urtica urens." Food Research 4, no. 5 (2020): 1487–92. http://dx.doi.org/10.26656/fr.2017.4(5).088.

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The antibacterial and antifungal activities of various extracts from Urtica urens were evaluated against selected microorganisms using agar hole-plate diffusion method. A total of ten extracts namely U. urens hexane leaf extract (HLE), chloroform leaf extract (CLE), ethyl acetate leaf extract (ELE), methanolic leaf extract (MLE), hexane stem-bark extract (HSB), chloroform stem-bark extract (CSB), ethyl acetate stem-bark extract (ESB), methanolic stem-bark extract (MSB), chloroform root extract (CRT) and methanolic root extract (MRT) were prepared. These extracts were evaluated against two Gram
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Pillai, M. K., L. I. Santi, and S. B. Mekbib. "Antimicrobial activities of extracts from stem bark of Tagetes minuta." Food Research 4, no. 6 (2020): 2089–94. http://dx.doi.org/10.26656/fr.2017.4(6).279.

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Tagetes minuta hexane stem bark extract (TMHESB), chloroform stem bark extract (TMCHSB), ethyl acetate stem bark extract (TMEASB) and methanolic stem bark extract (TMMESB) were evaluated for their antimicrobial activities using hole-plate diffusion method. Six bacterial isolates viz. Staphylococcus aureus, Listeria monocytogenes, Escherichia coli (wild), Escherichia coli (O157:H7), Pseudomonas aeruginosa and Serratia marcescens and two fungal isolates viz. Candida albicans and Penicillium digitatum were used for this study. The inhibition zones were found to be in the ranges of 10.0±1.6 to 15.
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Sieniawska, Elwira, Łukasz Świątek, Kouadio Ibrahime Sinan, et al. "Phytochemical Insights into Ficus sur Extracts and Their Biological Activity." Molecules 27, no. 6 (2022): 1863. http://dx.doi.org/10.3390/molecules27061863.

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This study focused on the biological evaluation and chemical characterisation of Ficus sur Forssk. (F. sur) (Family: Moraceae). The methanolic and aqueous extracts’ phytochemical profile, antioxidant, and enzyme inhibitory properties were investigated. The aqueous stem bark extract yielded the highest phenolic content (115.51 ± 1.60 mg gallic acid equivalent/g extract), while the methanolic leaves extract possessed the highest flavonoid content (27.47 ± 0.28 mg Rutin equivalent/g extract). In total, 118 compounds were identified in the tested extracts. The methanolic stem bark extract exhibite
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12

Zohdi, Rozaini Mohd, Shahida Muhamad Mukhtar, Nur Vicky Bihud, et al. "In vivo Antiplasmodial and Toxicological Effects of Goniothalamus lanceolatus Crude Extracts." Natural Product Communications 12, no. 8 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200826.

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This study is aimed at investigating the antiplasmodial activity and acute toxicity of the methanol (MeOH) extracts of the leaves and roots, and the dichloromethane (DCM) extracts of the stem bark, leaves, and roots of Goniothalamus lanceolatus. Phytochemical analysis was then carried out on the most active extract. In vivo antiplasmodial activity was assessed using the 4-day suppressive test against Plasmodium berghei ANKA (PbANKA) in mice. The plant extracts were administered intraperitoneally (i.p.) as a single dose (30 mg/kg) starting 4 h after infection. At a dose level of 30 mg/kg (i.p.)
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Solomon, Ermiyas, Abiyou Tilahun, Belete Tewabe, Abebe Tedla, and Minbale Gashu. "Antimicrobial activity and Antioxidant Property of Osyris abyssinica." BERHAN INTERNATIONAL RESEARCH JOURNAL OF SCIENCE AND HUMANITIES 8, no. 1 (2024): 49–61. https://doi.org/10.61593/dbu.birjsh.01.08.03.

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Osyris abyssinica (Syn Osyris quadripartite, Qeret in Amharic) belongs to Santalaceae family which is locally used to treat diarrhea, sexually transmitted diseases, anemia, cancer and wounds. The phytochemical constituents of the plant extracts were qualitatively assessed by the standard protocols. Methanol extract of root, stem bark and leaf of O. abyssinica contained terpenoid, flavonoid, tannin and phenolic compounds. Saponin was present in methanol extract of stem bark and root but not on the leaf. Alkaloid, tannin and phenol were also found in ethyl acetate extract of all plant parts. The
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14

Kazaure, Anisa Aliyu, Abdulsalami Muhammad Sani, Victoria Moltong Yilwan Dan, and Zahara. "Phytochemicals and antibacterial efficacy of <i>Annona muricata</i> (soursop) stem bark and leaf extracts against some clinical bacterial isolates." Science World Journal 20, no. 1 (2025): 214–22. https://doi.org/10.4314/swj.v20i1.28.

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The threat of drug-resistant pathogens necessitates exploring plant-derived bioactive compounds to develop potent antibacterial solutions. This study determined the phytochemicals and antibacterial activities of Annona muricata (soursop) stem bark and leaf extracts against some clinical bacterial isolates. The phytochemicals and antibacterial activity of leaf and stem bark extracts of Annona muricata were analyzed following standard methods. Invitro susceptibility of bacteria isolates to the plant extracts was evaluated using the agar well diffusion method. Minimum inhibitory concentration (MI
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15

Singh, Deeksha, Amit Nayak, Rakesh Yadav, and Uttam Singh Baghel. "ANTIULCER AND ANTI-INFLAMMATORY ACTIVITIES OF HYDROALCOHOLIC EXTRACTS OF STEM BARK AND LEAF OF ANOGEISSUS PENDULA EDGEW." INDIAN DRUGS 58, no. 01 (2021): 41–46. http://dx.doi.org/10.53879/id.58.01.11950.

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Anogeissus pendula Edgew has been reported to be used in gastric disorder even though no attempt has been made to evaluate the same. The present study was designed to evaluate the hydroalcoholic extracts of stem bark and leaves for in vivo acute antiulcer and anti-inflammatory activities. Antiulcer activity was studied by pylorus ligation induced ulcers while anti-inflammatory activities was studied by carrageenan induced paw edema. The extract of stem bark at 200 and 400 mg/kg b. w., significantly (P&lt;0.05) reduced ulcer index whereas extracts of both stem bark and leaves significantly (P&l
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16

Deethae, Aomhatai, Thongchai Sritapunya, Sunisa Khetnaoanurak, and Woraphob Jinwan. "Evaluation of Antibacterial, Antiinflammatory Activities and GC-MS Profiling of Millingtonia hortensis Linn. Leaf and Stem Bark Extracts." ASEAN Journal of Scientific and Technological Reports 26, no. 3 (2023): 72–80. http://dx.doi.org/10.55164/ajstr.v26i3.249339.

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The present study aimed to evaluate the antibacterial and antiinflammatory activity of Millingtonia hortensis Linn. leaf and stem bark extracts and identify the bioactive compounds by GC-MS analysis. This study determined the antibacterial activities using the agar disc diffusion technique. The results revealed the ethanol extract of M. hortensis Linn. stem bark was the highest potential inhibitory against gram-positive bacteria (Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, and Bacillus cereus). The minimum inhibitory concentration (MIC) and minimum bactericidal concentr
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Jaishwal, Nitesh, Mamta Jayswal, Deep Chand Gupta, et al. "Bioactive Potential of Pogostemon benghalensis (Burm.f.) Kuntze: Antibacterial, Antioxidant, and Xanthine Oxidase Inhibitory Activities." Bacteria 4, no. 1 (2025): 3. https://doi.org/10.3390/bacteria4010003.

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This research is focused on assessing the antibacterial properties of Pogostemon benghalensis stem bark and inflorescence extracts, as well as their inhibitory effects on xanthine oxidase, antioxidant potential, overall phenolic content, and flavonoid concentration. The cold maceration technique was used to obtain extracts using water, methanol, and ethyl acetate solvents. The disk diffusion method demonstrated the significant antibacterial efficacy of the methanol stem bark extract against Staphylococcus epidermidis, with a zone of inhibition (ZOI) of 13 mm, and the inflorescence methanol ext
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Jodi, S. M., N. Umar, H. Y. Ungo-kore, and Y. B. Ngwai. "ANTIMICROBIAL ACTIVITY OF ACACIA NILOTICA AGAINST SOME BACTERIAL ISOLATES ASSOCIATED WITH WOUND INFECTIONS." FUDMA JOURNAL OF SCIENCES 4, no. 2 (2022): 807–11. http://dx.doi.org/10.33003/fjs-2000-0402-1010.

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The search for biologically active compounds extracted from traditionally used plants is relevant due to the increasing resistance of bacteria to synthetic antibiotics and the occurrence of fatal opportunistic infections. Acacia nilotica, of the family leguminosae, is one of the oldest existing plant species having various therapeutic, biological and ethno-botanical claims and has diverse medicinal properties. This study was designed to determine the antimicrobial activity of leaf and stem-bark extract of Acacia nilotica against some bacterial isolates associated with wound infections. Leaf an
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Buduwara, J. H., R. S. Naphtali, T. Adiel, R. Sami, M. L. Tafem, and M. F. Tadouno. "Qualitative Phytochemical Screening and Larvicidal Efficacy of Physic Nut (Jatropha curcas) Leaves, Stem-bark and Root Extracts on Mosquito Larvae." Journal of Applied Life Sciences International 26, no. 6 (2023): 98–105. http://dx.doi.org/10.9734/jalsi/2023/v26i6631.

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The advance of battle by mosquito species to artificial chemicals has obliged the unrelenting pursuit of nontoxic ones from plants. This study screened the qualitative phytochemicals and evaluated the larvicidal efficacy of extracts of Jatropha curcas leaves, stem-bark and root extracts against third and fourth mosquito instar larvae. The J. curcas obtained were subjected to extraction by maceration. Qualitative phytochemical screening of ethanolic stem-bark, aqueous and ethanolic root extracts plants showed the presence of phenols, saponins, steroids flavonoids, alkaloids, glycosides, carbohy
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Shah, Harish, Arif Naseer, Nilesh Gupta, and Raj Singh. "A Study on HPTLC Quantification for Quality Control of Myricetin a Nutraceutical from Different Plant Parts of Myrica esculenta Linn." Biomedical and Pharmacology Journal 15, no. 1 (2022): 219–28. http://dx.doi.org/10.13005/bpj/2357.

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The present study was performed to report the quantification of myricetin present in different extracts (i.e. ethanol, methanol, petroleum ether, chloroform and aqueous extract) of root, leaf, bark, stem and seed of Myrica esculenta using TLC densitometric method. Densitometric scanning was performed at 366 nm for the determination and quantitation of standard compounds. The compact spots were achieved at Rf 0.67 corresponding to myricetin. The content of myricetin present in different solvent extracts of M. esculenta was 0.2159 ± 0.002% w/w, 0.3139 ± 0.003% w/w, 0.0184 ± 0.004% w/w, 0.0139 ±
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M., Gberikon G., Agbulu C.O, and Adeoti I.I. "Single and Combined Effects of Antibacterial Activities of Fruit and Stem Bark Extracts of Tetrapleura Tetraptera on Streptococcus Mutans and Pseudomonas Aeruginosa." International Journal of Sciences Volume 4, no. 2015-04 (2015): 46–49. https://doi.org/10.5281/zenodo.3348893.

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Single and combined effect of the antibacterial activities of fruit and stembark extracts of Tetrapleura tetraptera was carried out against Streptococcus mutans and Pseudomonas aeruginosa. Samples of T.tetraptera fruits were purchased in Wukari market, Taraba State. Stem bark samples were collected from Vandeikya, Benue State of Nigeria. Phytochemical analyses were carried out on both samples in the laboratory, Department of Biological Sciences, University of Agriculture, Makurdi. Phytochemical screening showed the presence of flavonoids, saponins, tannins, steroids, alkaloids, phlobatannins,
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Nabilah, Almurdani M., Rudi Hendra, and Hilwan Yuda Teruna. "Antioxidant activities of medang lendir (Litsea glutinosa) stem bark." Pharmacy Education 23, no. 2 (2023): 122–25. http://dx.doi.org/10.46542/pe.2023.232.122125.

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Background: Medang lendir (Litsea glutinosa), a member of the Lauraceae family, is typically found in the Kampar Regency area of Riau Province, Indonesia. This plant is frequently used in traditional medicine to treat rheumatism, diarrhea, and dysentery. Objective: To evaluate the antioxidant activities of L. glutinosa stem bark extracts. Method: L. glutinosa stem bark was macerated in methanol to obtain methanol extract, followed by partitioning with ethyl acetate to obtain ethyl acetate extract. The antioxidant activities of these extracts were determined using the NO radical scavenging and
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Babatunde, A. M. Yusuf, L. S. Kasim, and Adegbite A. Ayoade. "Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens." Malaysian Journal of Medical and Biological Research 3, no. 1 (2016): 7–10. http://dx.doi.org/10.18034/mjmbr.v3i1.399.

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The antimicrobial activity of oil and stem bark extracts of pentaclethra macrophylla benth was determined against staphylococcus aureus, streptococcus pneumonia, Eschericia coli, Haemophilus influenza, α-Haemolytic Streptococcus and Yeast, using hole diffusion method. The results revealed that the most inhibitory zone (25.0mm) was recorded in hexane oil extract against staphylococcus aureus and α-Haemolytic Streptococcus. The minimum inhibitory concentration (MIC) of the oil extract ranges between 7.8125-62.5mg/ml on all the test organisms and aqueous stem bark extract inhibited only Escherici
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YUSUF, Hajara Oyiza, Joshua OLU, and Charity Irekpita AKHIGBE. "Assessment of phytochemical constituents of Erythrophleum suaveolens (Brenan) stem bark extracts and its biological control of Aspergillus flavus isolated from Zea mays." Journal of Biotechnology 1, no. 1 (2022): 37–45. http://dx.doi.org/10.36108/jbt/2202.10.0130.

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This study set out to evaluate the phytochemical composition of Erythrophleum suaveolens stem bark extract and its fungicidal attributes towards Aspergillus flavus isolated from Zea mays. The stem bark extract was obtained using soxhlet extraction method with methanol, chloroform, and water as solvents. Qualitative and quantitative phytochemical analysis was then carried out to determine the concentration of phytochemicals present in the stem bark extracts, this were the tannin, flavonoid, saponin and phenol with a concentration of 2.47, 1.328, 2.72 and 0.838 mg/g respectively. For the antifun
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Hauwa Baba Umar, Saidu Abdulkadir, Basira Ibrahim, and Halima Ibrahim. "Phytochemical Screening, Acute Toxicity and Antibacterial Activity of Methanolic Stem Bark Extract of Hibiscus Rosa-Sinensis." International Journal of Emerging Multidisciplinaries: Biomedical and Clinical Research 2, no. 1 (2024): 9. http://dx.doi.org/10.54938/ijemdbmcr.2024.02.1.317.

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This study was conducted to determine the phytochemical constituents, acute toxicity and antibacterial activity of methanolic stem bark extract of. Hibiscus rosa-sinensis. The stem bark was collected, air dried, grounded and extracted using maceration method with methanol. The methanol extract of the stem bark was used for phytochemical screening, acute toxicity studies and anti-bacterial activity. The phytochemical screening of this extract revealed the presence of alkaloids, flavonoids, saponins, steroids, tannins, terpenoids, cardiac glycosides, carbohydrates except anthraquinones which was
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Muhammed, Bala. "Spathodea companulata (African tulip tree) stem and root barks extracts ameliorated N-nitroso diethylamine induced hepatic impairment in male rats." BIOMED natural and applied science 01, no. 01 (2021): 57–65. http://dx.doi.org/10.53858/bnas01015765.

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Spathodea campanulata Beauv. is an important plant widely used in traditional medicine for the treatment of hepatic disease. In the present study, we evaluate the phytochemical composition and hepatoprotective potential effect of the stem and root bark extracts of Spathodea companulata on dimethylnitrosamine (DEN) induced hepatic impairment in albino rats. Phytochemical compositions were analyzed using standard protocols. Forty-five male rats were grouped into 9 (A-I) of 5 rats each. Groups A-F were treated with stem bark extract, root bark extract, quercetin, DEN + stem bark extract, DEN + ro
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Kouitcheu, Mabeku Laure Brigitte, Thibau Flaurant Tchouangueu, and Emmanuel Talla. "Antimicrobial, Antioxidant and Protective Effect of Methanol Extract of Trichilia emetica (Meliaceae) Stem and Root Bark against Free Radical-induced Oxidative Haemolysis." European Journal of Medicinal Plants 19, no. 1 (2017): 1–14. https://doi.org/10.9734/EJMP/2017/33343.

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<strong>Background:</strong> The objectives of this study are to investigate the antimicrobial, antioxidant and antiradical properties of methanol extract of the stem and root bark of <em>Trichilia emetica</em> on a model of free radical-induced membrane damage. <strong>Methodology:</strong> p-Iodonitrotetrazolium chloride colorometric assay was used to determined bacterial and yeast susceptibility to plant samples. The antioxidant activity was evaluated using DPPH radical, hydroxyl radical, nitric oxide scavenging and reducing power assays. The cellular oxidative stress was evaluated through
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Umoke Chukwunalu Igbudu, Akuodor Godwin Christian, Okam Princeston Chukwuemeka, et al. "Hepatoprotective effect of the ethanol extract of Detarium senegalense stem bark in albino Wistar." International Journal of Biological and Pharmaceutical Sciences Archive 7, no. 1 (2024): 067–76. http://dx.doi.org/10.53771/ijbpsa.2024.7.1.0011.

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Aim: The hepatoprotective effect of Detarium senegalense ethanol stem bark extract was evaluated against paracetamol induced hepatic damage in albino rats. Material and methods: The ethanol stem bark extract of D. senegalense at doses of 100 mg/kg, 200 mg/kg and 400 mg/kg were orally administered once daily for 3 days.The liver function tests and biochemical investigation such as asparte transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin (TB) and direct bilirubin were carried out against paracetamol induced hepatotoxicity in rats. Phytochemical investig
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Ekpeno, Josiah Nkop, and Chuks Zudonu Onisoman. "Phytochemical Screening and Antimicrobial Activity of Leave and Stem Bark of Dillenia indica Linn." Pharmaceutical and Chemical Journal 7, no. 1 (2020): 1–4. https://doi.org/10.5281/zenodo.13951301.

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This study was aimed at determining the phytochemical profile and antimicrobial activity of leave and stem bark. The phytochemical and antimicrobial activity of ethanol extracts of leave and stem bark of <em>Dillenia indica </em>was evaluated using standard methods. The phytochemical screening of the leave and stem bark extracts revealed the presence of saponins, glycosides, phenols, alkaloids, flavonoids, tannins, carbohydrates and resins in varying quantities while anthraquinones was absent in both leave and stem bark extract.<em> Dillenia indica </em>ethanol extracts of the leave and stem b
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Noviyanti, Amalia, I. Wayan Arya Krishnawan Firdaus, and Rahmad Arifin. "THE EFFECT OF IRONWOOD STEM BARK EXTRACT (Eusideroxylon zwageri) ON THE GROWTH OF Streptococcus mutans ON ACRYLIC RESIN DENTURE PLATE." Dentino : Jurnal Kedokteran Gigi 6, no. 1 (2021): 13. http://dx.doi.org/10.20527/dentino.v6i1.10634.

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ABSTRACTBackground: Streptococcus mutans is plaque-forming initiator bacteria. Plaque on the surface base of denture can cause color changing, bad breath, inflammation, and infection called denture stomatitis. Denture hygiene must be maintained by denture soaking in 0.2% chlorhexidine gluconate. However, 0.2% chlorhexidine gluconatethat used incessantly can cause side effects such as the changing of denture color and the fading of denture base pigmentation. The ironwood stem bark extract can be an alternative for denture cleanser material. Objectives: To analyze the effect of ironwood stem bar
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Ugwu, Chinenye Nnenna, Ezinwanne Nneoma Ezeibe, Chinekwu Sherridan Nwobi, et al. "Preparation and evaluation of burns wound healing ointment base of leaves and stem bark of Anthocleista djalonensis (L) extract using animal model." INTERNATIONAL JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (IJPER) 1, no. 02 (2020): 25–32. http://dx.doi.org/10.37021/ijper.v1i2.1.

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BACKGROUND: Burn wounds are inescapable life events especially in low income areas. Contamination of the burn wound site results in localized wound infection, hence the need for potent phytochemicals readily available for wound healing. The use of stem bark of Anthocleista djalonensis efficacy for burn wound has not been evaluated to the best of our knowledge.&#x0D; AIM: The study is aimed at evaluating and comparing the wound healing potential of ointment base of leaves and Stem bark of Anthocleista djalonensis on burn wounds created on wistar albino rats.&#x0D; METHODS: The leaves and Stem b
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Asanga, Edet E., Henshaw Okoroiwu, Uwem O. Edet, et al. "Antimalarial activity of Mangifera indica aqueous extract in Plasmodium berghei’s apicoplast." Tropical Journal of Pharmaceutical Research 22, no. 5 (2023): 1007–15. http://dx.doi.org/10.4314/tjpr.v22i5.11.

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Purpose: To investigate the in vivo antiplasmodial effect of Mangifera indica aqueous extract in Plasmodium berghei-infected mice, and to characterize its phytochemical constituents and their mechanism of action.&#x0D; Methods: The plant leaves (250.71 g) and stem bark (509.34 g) were weighed, macerated in 5 L of boiled, distilled water for 72 h, and filtered. In vivo antiplasmodial evaluation of the extract was carried out using Plasmodium berghei-infected mice. The leaf and stem bark extracts were subjected to gas chromatography-mass spectroscopy (GC-MS) analysis for characterization of thei
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Bakar, Kassim, Nilofar, Andilyat Mohamed, et al. "Evaluating Phytochemical Profiles, Cytotoxicity, Antiviral Activity, Antioxidant Potential, and Enzyme Inhibition of Vepris boiviniana Extracts." Molecules 28, no. 22 (2023): 7531. http://dx.doi.org/10.3390/molecules28227531.

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In the present study, we performed comprehensive LC-MS chemical profiling and biological tests of Vepris boiviniana leaves and stem bark extracts of different polarities. In total, 60 bioactive compounds were tentatively identified in all extracts. The 80% ethanolic stem bark extract exhibited the highest activity in the ABTS assay, equal to 551.82 mg TE/g. The infusion extract of stem bark consistently demonstrated elevated antioxidant activity in all assays, with values ranging from 137.39 mg TE/g to 218.46 mg TE/g. Regarding the enzyme inhibitory assay, aqueous extracts from both bark and l
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Nesa, M., S. Islam, S. K. Sharma, S. B. Rekha, J. Ferdous, and N. Islam. "Bioactive Potentials of Cassia renigera Benth. Extracts against the Stored Product Pests Callosobruchus chinensis L., Sitophilus oryzae L. and Tribolium castaneum (Hbst.)." Journal of Scientific Research 9, no. 4 (2017): 351–57. http://dx.doi.org/10.3329/jsr.v9i4.32588.

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Petroleum (Pet.) ether, CHCl3 and CH3OH extracts of Cassia renigera Benth. were tested against Callosobruchus chinensis L. for dose-mortality and repellency; and against Sitophilus oryzae L. and Tribolium castaneum (Hbst.) for repellent activity test. The Pet. ether extract of leaf was found active against C. chinensis adults through dose mortality assay and the LD50 values established were 9.270, 4.932, 2.032, 1.721, 1.671, 1.543, 1.513, 1.503 and 1.478 mg cm-2 for 0.5, 6, 12, 18, 24, 30, 36, 42 and 48 h of exposure respectively. However, the leaf extracts of CHCl3 and CH3OH; as well as the P
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Hasballah, Kartini, Murniana ., Erya ., and Ardian . "CYTOTOXIC BIOACTIVE COMPOUNDS FROM CALOTROPIS GIGANTEA STEM BARK." International Journal of Pharmacy and Pharmaceutical Sciences 8, no. 9 (2016): 111. http://dx.doi.org/10.22159/ijpps.2016.v8i9.12430.

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&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The present study deals with the cytotoxic activity of n-hexane and ethyl acetate extracts of &lt;em&gt;Calotropis gigantea&lt;/em&gt; L. stem bark and its fractions such as A, B, C, D and E fractions on murine leukemia cell line P388.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The crude extracts of &lt;em&gt;C. gigantea&lt;/em&gt; stem bark were prepared using n-hexane and ethyl acetate solvents. The plant extracts were subjected to vacuum liquid chromatography followed by TLC. According to the similarity of stain patterns, the fra
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Safrida, Safrida, and Mustafa Sabri. "Effect of Carica papaya L. Stem Bark Extracts on Cholesterol Concentration in Rats Induced with Streptosozin." E3S Web of Conferences 151 (2020): 01011. http://dx.doi.org/10.1051/e3sconf/202015101011.

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This study was designed to determine the effect of Carica papaya L. stem bark extracts on cholesterol concentration in rats induced with glibenclamide. A completely randomized design was used for the experiment which consisted of 6 treatment groups, each group consisted of four rats, as follows:1) KN (negative control, non-diabetic rats); KP, diabetic rats given glibenclamide 10 mg/kg body weight; EP 1, diabetic rats given 0 mg/kg body weight/day extract; EP2, diabetic rats given 100 mg/kg body weight/day extract; and EP3, diabetic rats given 200 mg/kg body weight/day extract, EP4, diabetic ra
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Trindade, Roseane Cristina Prédes, Paulo Pedro da Silva, João Xavier de Araújo-Júnior, Ivanildo Soares de Lima, José Elias de Paula, and Antônio Euzébio Goulart Sant'Ana. "Mortality of Plutella xylostella larvae treated with Aspidosperma pyrifolium ethanol extracts." Pesquisa Agropecuária Brasileira 43, no. 12 (2008): 1813–16. http://dx.doi.org/10.1590/s0100-204x2008001200024.

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The objective of this work was to assess the effects of Aspidosperma pyrifolium ethanol extracts on cabbage moth (Plutella xylostella) larvae. The ethanol extracts of the stem bark, fruits and roots of A. pyrifolium were obtained by classical phytochemical methods, and the resulting subfractions were tested on P. xylostella, using 4 and 5 mg L-1. The crude ethanol extract of the stem bark was more lethal. The alkaloid-rich aqueous subfraction derived from the stem bark extract caused 100% larval mortality at 4 mg L-1. Insecticidal activity was associated with the presence of the monoterpenoid
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38

Miranda, Isabel, Joana Ferreira, Sofia Cardoso, and Helena Pereira. "Composition and antioxidant properties of extracts from Douglas fir bark." Holzforschung 75, no. 7 (2021): 677–87. http://dx.doi.org/10.1515/hf-2020-0097.

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Abstract This study aimed to investigate the antioxidant ability and the chemical composition of apolar and polar extractives from Douglas-fir bark, cork and phloem, establishing a possible correlation with the structural variation along the tree stem and geographic location. Douglas-fir bark extractives’ composition were analyzed at three stem heights in trees from two locations. Cork and phloem extracts’ composition were analyzed in samples collected at stem base. Extractives content in Douglas-fir bark varied between 14 and 31% and polar extractives (11–29%) were dominant over non-polar. Li
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Ndung’u, James, Joseph Nguta, Isaac Mapenay, and Gervason Moriasi. "Antimicrobial Activity, Cytotoxicity, and Qualitative Phytochemistry of Leaf, stem bark, and root bark extracts from Prunus africana (Hook. F.) Kalkman." Journal of Phytopharmacology 13, no. 2 (2024): 122–32. http://dx.doi.org/10.31254/phyto.2024.13206.

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The rise of resistant strains poses a significant public health risk, particularly, in sub-Saharan Africa, where over 50% of global infectious disease-associated deaths occur, highlighting the urgent need for novel, safe, affordable, and accessible antimicrobials. Accordingly, we investigated the antimicrobial activity, cytotoxicity, and qualitative phytochemistry of the aqueous, hydroethanolic, and acetonic leaf, stem bark, and root bark extracts of Prunus africana (Hook. F.) Kalkman, based on its ethnomedicinal information. The results showed the aqueous root bark and aqueous/acetonic stem b
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Ali, Audu, and Muhammad Ibrahim Usman. "Hepatocurative Properties of Eucalyptus camaldulensis Stem Bark Extract." East African Scholars Journal of Agriculture and Life Sciences 5, no. 7 (2022): 146–50. http://dx.doi.org/10.36349/easjals.2022.v05i07.003.

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The research investigates the hepatocurative potentials of Eucalyptus camaldulensis solvents extract on CCl4 induced liver damage using albino rats, partial characterization of the most active extract was done using GCMS techniques. Forty-two rats were placed into seven groups of six rats each. Group I and II were normal control and test control respectively. Groups III to VII were induced with liver damage using 120mg/kg of CCl4 and administered with standard drug, n-hexane extract (E1), chloroform extract (E2), ethyl acetate extract (E) and methanol extract (E4) respectively. 24 hours after
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41

Uadia, Jeremiah Ogboma, and Osahon Kennedy Ogbeide. "Comparative Studies of the Phytochemical Analysis, Mineral Content, Antibacterial Activity and Antioxidant Potential of Ethyl Acetate Extract of Alstonia Boonei Leaves and Stem Bark." Walisongo Journal of Chemistry 7, no. 1 (2024): 57–69. https://doi.org/10.21580/wjc.v7i1.20667.

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Folkloric medicine has reported the effectiveness of Alstonia boonei stem bark and leaf extracts in treating and managing different ailments. Hence, this research is a comparative evaluation of the phytochemicals; antioxidant potential, mineral content, and antibacterial capacity of ethyl acetate extract of Alstonia boonei leaves and stem bark. Phytochemical analysis was determined using standard methods; mineral composition was determined using a flame photometer and an atomic absorption spectrophotometer; antibacterial capacity was analysed by agar-well diffusion method; and antioxidant pote
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Peter Onyedikachi Opara, Victor H.A. Enemor, Emeka Sabastine Asiwe, Emmanuela Uchechi Enenebeaku, and Augustus Kelechi Ahamefule. "Gas chromatography-mass spectrometry and acute toxicity studies of Annona muricata Ethanol stem bark extract." GSC Advanced Research and Reviews 20, no. 1 (2024): 139–46. http://dx.doi.org/10.30574/gscarr.2024.20.1.0234.

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Plants with therapeutic potentials are considered to be the main source of phytoconstituents that can be used for the treatment of various ailments. This work focuses on determining the acute toxicity and the phytochemical constituents present in ethanol stem bark extracts of Annona muricata using Gas chromatography-mass spectroscopy. Lorke's toxicity testing method was used to determine the acute toxicity of the A. muricata stem bark extract. The result of the quantitative phytochemical GC-MS analysis of the stem bark showed that the ethanol stem bark extracts contained 13 compounds at differ
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Abd, El-Nasser B. El-Sayed, and A. El-Sherbeni Suzy. "Efficacy of Cassia nodosa extracts in the management of cercospora leaf spot of sugar beet caused by Cercospora beticola." Chemistry Research Journal 2, no. 4 (2017): 158–70. https://doi.org/10.5281/zenodo.13954507.

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<em>Cercospora beticola</em>, the causative agent of cercospora leaf spot (CLS) disease, is a serious problem that remarkably impact the yield of sugar beet worldwide. Our aim was to assess the antifungal effect of a natural and more safe extracts of Leaves, flowers and stem bark of <em>Cassia nodosa</em> and salicylic acid (SA) individually or in combination relative to the recommended treatment tetraconazole fungicide. The fungicidal effect was assessed <em>in vitro</em> by measuring the radial growth of <em>C.</em> <em>beticola</em> and <em>in vivo</em> by determining the alteration in CLS
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Owaba, Azibanasamesa D. C., Emmanuel I. Etim, and Ekarika C. Johnson. "Comparative Haematological Effect of Seed and Stem Bark Extracts of Carapa procera D.C Meliaceae in Male Rodents." Journal of Phytopharmacology 11, no. 2 (2022): 137–41. http://dx.doi.org/10.31254/phyto.2022.11216.

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Background: Blood system plays a vital role in the survival of mammals. Carapa procera is a medicinal plant which the seed is used in treatment of malaria while stem bark is used for the management of male erectile dysfunction in folkloric medicine. Objective: Evaluation of the hematological parameter is a tool to assess toxicity and to corroborate the safety or otherwise of this medicinal plant in humans. Methods: The seed and stem bark were collected from the wild and extracted using cold maceration and LD50 were determined using Lorke’s method. The extracts and fractions were administered a
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Oluwayemisi Odeyemi, Anthony Uchenna Onochie, Sunday Oluwaseun Odeyemi, and Ifeanyi Onyema Oshim. "Evaluation of qualitative and quantitative phytochemical constituents of Napoleona imperialis stem bark." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 202–8. http://dx.doi.org/10.30574/gscbps.2023.24.1.0246.

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The aim of this study was to determine the qualitative and quantitative phytochemicals of Napoleona imperialis stem bark. Methods: Extractions and Phytochemical analysis of Napoleona imperialis stem bark were done using standard procedures. Result: Aqueous Napoleona imperialis stem bark extract had yield of 76.9g (7.69%) and methanol Napoleona imperialis stem bark extract also yielded 58.5g (5.85%) when 1000g pulverized was used for each. Qualitative phytochemical analysis of this extract exhibited moderate quantities of alkaloid, steroid and terpenoid in aqueous extract while methanol extract
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Ambarwati, Neneng Siti Silfi, and Berna Elya. "Tyrosinase Inhibitory Activity of The Extracts from Garcinia lateriflora Blume var. Javanica Boerl, Garcinia fruticosa Lauterb, and Garcinia xanthochymus." Journal of Pharmaceuticals and Natural Sciences 1, no. 1 (2024): 35–40. http://dx.doi.org/10.70392/drty6950.

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Tyrosinase overexpression in humans increases melanin production in the skin, which may have hyperpigmentation-causing effects. In this study, various extracts from the Garcinia lateriflora Blume var. Javanica Boerl, Garcinia fruticosa Lauterb, and Garcinia xanthochymus plants were tested for their ability to inhibit the tyrosinase enzyme. The results showed that the G. fruticosa Lauterb stem bark hexane extract had the highest activity followed succesively by the G. lateriflora Blume var javanica Boerl leaf methanol extract, G xanthochymus mesocarp hexane extract, G. xanthochymus mesocarp met
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Imade, R. O., M. Chikunie-Ofulue, M. I. Choudharyi, and A. Alam. "Cytotoxic Activity jof Dialium Guineense Wild (Fabaceae) Fruit and Stem Bark Methanol Extracts and Fractions." Nigerian Journal of Pharmaceutical Research 17, no. 1S (2022): 15–21. http://dx.doi.org/10.4314/njpr.v17i1s.2s.

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Background: Cancer is a disease characterized by uncontrollable multiplication and spread of abnormal forms of the body’s own cells. Due to the challenges of orthodox drugs other treatment options are being investigated. Dialium guineense has found ethnomedicinal application in the management of various ailments including cancer.&#x0D; Objectives: To evaluate the cytotoxic activity of D. guineense fruit and stem bark extracts using preliminary and confirmatory methods.&#x0D; Material and method: Preliminary screening was carried out on the extracts using bench-top assay methods for cytotoxicit
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K., Arunkumar, and K. R. Chandrashekar. "PHYTOCHEMICAL EVALUATION AND IN VITRO ANTIMICROBIAL AND ANTIOXIDANT STUDIES OF LEAF AND STEM BARK EXTRACTS OF POLYALTHIA FRAGRANS (DALZ.) BEDD.–AN ENDEMIC SPECIES OF WESTERN GHATS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 8 (2017): 20. http://dx.doi.org/10.22159/ijpps.2017v9i8.13915.

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Objective: Phytochemical constituents of various solvent extracts of leaf and stem bark of Polyalthia fragrans (Dalz.) Bedd were screened. Antimicrobial and antioxidant activities of the extracts were evaluated.Methods: Crude extracts of methanol, ethyl acetate, chloroform and aqueous of leaf and stem bark were evaluated for antimicrobial activity by disc diffusion method and antioxidant activity by DPPH (diphenyl-2-picrylhydrazyl) radical scavenging and reducing power assay. Quantitative analysis of total phenolics was done by the Folin-Ciocalteau method and total flavonoids by aluminum chlor
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Okoye, Nkeoma Nkasi, Nwando Joy Nwokoye, Chidimma Malinda Muobike, Francesca Ogechukwu Ojoko, Deborah Amarachi Emmanuel, and Faithful Oluchukwu Uche. "Comparative phytochemical and antioxidant studies of the hexane and ethyl acetate fractions of the methanol extracts of the stem bark of Allophylus africanus." Journal of Current Biomedical Research 4, no. 6 (2024): 1884–92. https://doi.org/10.54117/jcbr.v4i6.2.

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This research is aimed at comparing the phytoconstituents and antioxidant activities of the methanol extract, hexane and ethyl acetate fractions of the stem bark of Allophylus africanus Beauv. for development into possible phytopharmaceuticals. About 500 g dry weight of the stem bark sample was macerated for a total of 48 h using 5 L methanol to obtain the methanol extract. The extract was fractionated into hexane and ethyl acetate and each fraction monitored using Thin Layer Chromatography (TLC). The extract and fractions were also subjected to phytochemical screening. Using the DPPH radical
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Musa, Kabiru, and Mohd Adamu. "Antimicrobial Effects of (Miswak Stick) Salvadora persica Extracts Against Oral Harmful Bacteria." International Journal of Advanced Academic Research 11, no. 3 (2025): 27–39. https://doi.org/10.5281/zenodo.15111859.

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<em>Salvadora persica, a traditional medicinal plant, has been used for centuries to prevent and treat oral diseases. This study aimed to evaluate the phytochemical constituents and antimicrobial activity of Salvadora persica stem bark extracts against oral bacterial pathogens. The methanol and aqueous extracts of Salvadora persica stem bark were analyzed for their phytochemical constituents and antimicrobial activity using the disc diffusion method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were also determined. The results showed that both extrac
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