Academic literature on the topic 'Steroid-induced cognitive impairment'

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Journal articles on the topic "Steroid-induced cognitive impairment"

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Laurie, Jo Moore, Goldner Vukov Mila, Huso Rachel, Ishino Risa, and Althauser Samuel. "Preliminary Study of the Possible Benefit of the Reversible Acetylcholinesterase Inhibitor Donepezil for Cognitive Impairment Associated with Corticorticosteroid Treatment for Presumptive Neurosarcoidsosis with a Lesion in the Right Basal Ganglia and Thalamus." British Journal of Medicine & Medical Research 21, no. 12 (2017): 1–6. https://doi.org/10.9734/BJMMR/2017/33821.

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<strong>Aims:</strong> To present the case of a patient diagnosed by neurology with neurosarcoidsosis with cognitive impairment after long-term treatment with corticosteroids who showed marked improvement in his cognition upon initiation of donepezil. To provide a brief overview of the treatment of neurosarcoidosis and corticosteroid-induced cognitive disorders with acetylcho-linesterase inhibitors and clarify any literature regarding the use of acetylcholinesterase inhibitors in neurosarcoidosis. <strong>Presentation of Case:</strong> G.A. was a 46-year-old African American veteran who spent
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Bender, Bruce G., Louise Belleau, Jolene T. Fukuhara, David A. Mrazek, and Robert C. Strunk. "Psychomotor Adaptation in Children With Severe Chronic Asthma." Pediatrics 79, no. 5 (1987): 723–27. http://dx.doi.org/10.1542/peds.79.5.723.

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Acute effects of steroid medications or hypoxic-induced brain damage have been hypothesized to cause neuropsychologic impairment in children with severe asthma. The present investigation included neuromotor, cognitive, psychosocial, and medical evaluations of 67 hospitalized asthmatic children from 9 to 14 years of age, at risk for motor dysfunction. Mean scores from the Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) were similar to test norm means and were not indicative of neuromotor impairment. Scores of the BOTMP correlated significantly (P &amp;lt; .01) with measures of child and f
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Song, Xiaoxuan, Zeyu Zhu, Xiaohang Qian, Xiaoli Liu, Shengdi Chen, and Huidong Tang. "Multi-Omics Characterization of Type 2 Diabetes Mellitus-Induced Cognitive Impairment in the db/db Mouse Model." Molecules 27, no. 6 (2022): 1904. http://dx.doi.org/10.3390/molecules27061904.

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Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder frequently accompanied by cognitive impairment. Contributing factors such as modern lifestyle, genetic predisposition, and gene environmental interactions have been postulated, but the pathogenesis remains unclear. In this study, we attempt to investigate the potential mechanisms and interventions underlying T2DM-induced cognitive deficits from the brain–gut axis perspective. A combined analysis of the brain transcriptome, plasma metabolome, and gut microbiota in db/db mice with cognitive decline was conducted. Transcriptome analy
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Manzo, Ciro, Jordi Serra-Mestres, Alberto Castagna, and Marco Isetta. "Behavioral, Psychiatric, and Cognitive Adverse Events in Older Persons Treated with Glucocorticoids." Medicines 5, no. 3 (2018): 82. http://dx.doi.org/10.3390/medicines5030082.

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Background: Since the introduction of glucocorticoids (GCs) in the physician’s pharmacological arsenal, it has been known that they are a cause of behavioral or psychiatric adverse events (BPAE), as well as of cognitive problems. To the best of our knowledge, the relationship between these adverse events and GCs in older persons has never been evaluated, except through case-reports or series with few cases. In this paper, a review of the literature regarding BPAEs and cognitive disorders in older people treated with CSs is undertaken. Methods: A comprehensive literature search for BPAEs was ca
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Ramanan, Sriram, Weiling Zhao, David R. Riddle, and Mike E. Robbins. "Role of PPARs in Radiation-Induced Brain Injury." PPAR Research 2010 (2010): 1–12. http://dx.doi.org/10.1155/2010/234975.

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Whole-brain irradiation (WBI) represents the primary mode of treatment for brain metastases; about 200 000 patients receive WBI each year in the USA. Up to 50% of adult and 100% of pediatric brain cancer patients who survive &gt;6 months post-WBI will suffer from a progressive, cognitive impairment. At present, there are no proven long-term treatments or preventive strategies for this significant radiation-induced late effect. Recent studies suggest that the pathogenesis of radiation-induced brain injury involves WBI-mediated increases in oxidative stress and/or inflammatory responses in the b
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Li, Xiayahu, Weiguo Zhou, Kai Zhao, and Yaolin Li. "A case of disseminated nocardia infection with initial symptoms manifesting as cognitive impairment: Case report and literature review." Medicine 103, no. 49 (2024): e39535. https://doi.org/10.1097/md.0000000000039535.

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Rationale: Nocardia infections, although rare, pose significant challenges in diagnosis and treatment, especially when involving the central nervous system (CNS). Mortality rates in such cases can be high, highlighting the need for early recognition and tailored antimicrobial therapy. Patient concerns: A 58-year-old male with a history of chronic obstructive pulmonary disease, antineutrophil cytoplasmic antibody–associated glomerulonephritis, and steroid-induced diabetes mellitus presented with disorganized speech, fever, cough, dyspnea, and psychiatric symptoms. Diagnoses: The patient was dia
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Tarsin, Walid Y., Samia M. Farrara, Hana M. Abusaida, et al. "Vitamin D Improves Dementia Induced by Scopolamine in Mice: Histological Study." South Asian Research Journal of Pharmaceutical Sciences 5, no. 04 (2023): 114–31. http://dx.doi.org/10.36346/sarjps.2023.v05i04.004.

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In Dementia, there is a deterioration in cognitive ability, which affect memory, thinking, and the ability to perform daily activities. Vitamin D is a steroid hormone; its deficiency may play an aggressive role in neurodegeneration disorders. Scopolamine is a muscarinic receptor antagonist that induces memory impairment and oxidative stress. The aim of the work is to determine the histological effect of vitamin D on dementia induced by scopolamine in albino mice. Male albino mice were divided into eight groups of six each. Group 1: Administered T80(1%) for one week, Group 2: Administered scopo
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Maksimovic, Stefan, Nemanja Useinovic, Nidia Quillinan, Douglas F. Covey, Slobodan M. Todorovic, and Vesna Jevtovic-Todorovic. "General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action." International Journal of Molecular Sciences 23, no. 3 (2022): 1889. http://dx.doi.org/10.3390/ijms23031889.

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Over the past three decades, we have been grappling with rapidly accumulating evidence that general anesthetics (GAs) may not be as innocuous for the young brain as we previously believed. The growing realization comes from hundreds of animal studies in numerous species, from nematodes to higher mammals. These studies argue that early exposure to commonly used GAs causes widespread apoptotic neurodegeneration in brain regions critical to cognition and socio-emotional development, kills a substantial number of neurons in the young brain, and, importantly, results in lasting disturbances in neur
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Seymour, Niall, Muhammad Fahmi Ismail, Kieran Doherty, et al. "Steroid‐Induced Mental Disorders in Oncology Patients: A 10‐Year Retrospective Case Series Review." Psycho-Oncology 34, no. 4 (2025). https://doi.org/10.1002/pon.70137.

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ABSTRACTObjectivePatients with cancer are commonly prescribed corticosteroids for a variety of indications. Corticosteroids have long been known to affect mental state. Neuropsychiatric effects range from insomnia, cognitive impairment, and mood symptoms to psychosis and mania. In this study, we aimed to investigate the demographics, steroid exposure, referring indications, symptom profiles, and subsequent treatments of steroid‐induced mental disorders in oncology patients.MethodsWe conducted a retrospective chart review of patients diagnosed with a steroid‐induced mental disorder, as assessed
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Yin, Wei, Jie Zhang, Yao Guo, Zhibing Wu, Can Diao, and Jinhao Sun. "Melatonin for premenstrual syndrome: A potential remedy but not ready." Frontiers in Endocrinology 13 (January 9, 2023). http://dx.doi.org/10.3389/fendo.2022.1084249.

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Premenstrual syndrome (PMS), a recurrent and moderate disorder that occurs during the luteal phase of the menstrual cycle and quickly resolves after menstruation, is characterized by somatic and emotional discomfort that can be severe enough to impair daily activities. Current therapeutic drugs for PMS such as selective serotonin reuptake inhibitors are not very satisfying. As a critical pineal hormone, melatonin has increasingly been suggested to modulate PMS symptoms. In this review, we update the latest progress on PMS-induced sleep disturbance, mood changes, and cognitive impairment and pr
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