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Journal articles on the topic 'Steroid Side effects'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Grennan, Dara, and Sheila Wang. "Steroid Side Effects." JAMA 322, no. 3 (2019): 282. http://dx.doi.org/10.1001/jama.2019.8506.

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Aljubori, Nemah. "Misuses and side effects of steroids derivatives." INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 2, no. 1 (2019): 1–4. http://dx.doi.org/10.32441/ijms.2.1.1.

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The term Steroid, denotes any of a class of natural or synthetic organic compounds characterized by a molecular structure of 17 carbon atoms arranged in four rings. Steroids are important in biology, chemistry, and medicine. They are classified into two major categories; the catabolic and the anabolic steroids. The catabolic steroids include corticosterone cortisone and aldosterone. The maincorticosteroids produced by the adrenal cortex are cortisol and aldosterone

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Lin, Kenny, Claire Stewart, Philip Steig, Cameron Brennan, Philip Gutin, and Samuel Selesnick. "Incidence of Prolonged Systemic Steroid Treatment after Surgery for Acoustic Neuroma and Its Implications." Journal of Neurological Surgery Part B: Skull Base 79, no. 06 (2018): 559–68. http://dx.doi.org/10.1055/s-0038-1641752.

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Objectives To determine the incidence of prolonged postoperative systemic corticosteroid therapy after surgery for acoustic neuroma as well as the indications and associated risk factors that could lead to prolonged steroid administration, and the incidence of steroid-related adverse effects. Study Designs Retrospective chart review. Methods Retrospective chart review of patients undergoing resection of acoustic neuroma between 2010 and 2017 at two tertiary care medical centers. Patient and tumor characteristics, operative approach, hospital length of stay, initial postoperative taper length,

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Pandav, SS, Savleen Kaur, Sushmita Kaushik, and Sonia Phulke. "Steroid-induced Glaucoma: An Avoidable Irreversible Blindness." Journal of Current Glaucoma Practice 11, no. 2 (2017): 67–72. http://dx.doi.org/10.5005/jp-journals-10028-1226.

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ABSTRACT Steroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects. Among the ocular side effects, cataract and glaucoma are common. Steroid-induced ocular hypertension was reported in 1950, when long-term use of systemic steroid was shown to increase the intraocular pressure (IOP). Chronic administration of steroids in any form with raised IOP can cause optic neuropathy resultin

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Dr., Rao Muhammad Adnan Dr. Muhammad Naveed Akbar Khan Dr. Muhammad Zahid Khan. "AWARENESS AND ATTITUDE TOWARD USE AND SIDE EFFECTS OF STEROIDS: A CROSS SECTIONAL STUDY OF HEALTH PROFESSIONALS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 14345–53. https://doi.org/10.5281/zenodo.1974660.

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<em>The term steroid means molecule having varying physiological properties. Initially steroids were isolated from adrenal gland and were thought to use in Addison disease. Now due to its potent anti-inflammatory and immune modulating properties steroids are used in many clinical problems. Testosterone exerts its effect on both reproductive and non-reproductive tissues. It is mostly used to increase muscle strength, increase muscle mass, decreased recovery time and promote healing. People may experience some side effects like euphoria, aggressive behavior and diminished fatigue during steroid

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Kershner, Pamela, and Rebekah Wang-Cheng. "Psychiatric Side Effects of Steroid Therapy." Psychosomatics 30, no. 2 (1989): 135–39. http://dx.doi.org/10.1016/s0033-3182(89)72293-3.

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Hamad, Sara G., Mutasim Abu-Hasan, and Atqah AbdulWahab. "Use of Intravenous Pulse Steroids to Treat Allergic Bronchopulmonary Aspergillosis in a Non-Compliant Asthmatic Adolescent." Children 9, no. 2 (2022): 252. http://dx.doi.org/10.3390/children9020252.

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Allergic bronchopulmonary aspergillosis (ABPA) is an immune-mediated inflammatory airway disease that predominantly affects patients with cystic fibrosis (CF) and, less commonly, patients with asthma. ABPA can lead to irreversible lung injury and bronchiectasis if not treated early and aggressively. Long-term oral steroids are the standard therapy of ABPA. However, it is associated with an increased risk of steroids side effects and possible medication noncompliance. Monthly intravenous pulse methylprednisolone (IV-PS) has been used as an alternative to oral steroids to treat CF-related ABPA w

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Ahmed, Mohammed, Success Tobore Oyibo, Shailesh Dalvi, and Richard Cowell. "Hydrocortisone-induced symptomatic sinus bradycardia." BMJ Case Reports 15, no. 11 (2022): e252878. http://dx.doi.org/10.1136/bcr-2022-252878.

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Steroids are commonly prescribed medications that have a wide range of adverse effects. Bradycardia is one of the rare but significant side effects of steroid use, and only a few cases have been reported with bradycardia as a side effect. In this report, we present a case of a woman in her early 50s who developed severe symptomatic sinus bradycardia following high-dose administration of intravenous hydrocortisone, initiated for acute exacerbation of Crohn’s disease. Her symptoms entirely resolved after discontinuation of the steroid. This case highlights the importance of obtaining baseline EC

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Kouhi, Ali, Sasan Dabiri, Amin Amali, et al. "Study of Steroid Effects on Graft and Inner ear Outcomes in Tympanoplasty: Randomized Controlled Trial." Ear, Nose & Throat Journal 97, no. 6 (2018): 163–66. http://dx.doi.org/10.1177/014556131809700613.

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More studies are needed to investigate the side effects of steroids in tympanoplasty, owing to the paucity of such studies in the literature. This randomized, controlled clinical trial included 59 patients with chronic otitis media who underwent tympanoplasty and were randomized after surgery to a systemic steroid or no steroid treatment. Patients were randomized into two groups. Perforation size, graft outcome, and complications such as tinnitus and hearing loss were compared between the two groups. Postsurgical steroid injection had no effect on graft outcome ( p = 0.927) or tinnitus ( p = 0

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Hricik, D. E., W. L. Kupin, and M. R. First. "Steroid-free immunosuppression after renal transplantation." Journal of the American Society of Nephrology 4, no. 8 (1994): S10. http://dx.doi.org/10.1681/asn.v48s10.

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Concerns about the side effects of chronic steroid therapy have prompted increasing interest in steroid-free immunosuppression for renal transplant recipients who are maintained on cyclosporine-based regimens. Studies to date suggest that at least 50% of cyclosporine-treated patients can be managed without steroid therapy. Reported benefits of avoiding or withdrawing steroid therapy have included improvements in hyperlipidemia, hypertension, and glucose intolerance and accelerated growth in children. Whether these effects will increase patient or allograft survival remains to be proved. Furthe

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Dr., Rajkumar Kothiwala, Deepak S. Bohra Dr., Rakesh Kumar Dr., et al. "Alarming tropical steroid misuse on face: A descriptive study." Alarming tropical steroid misuse on face: A descriptive study 3, no. 7 (2017): 210–14. https://doi.org/10.5281/zenodo.837290.

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<strong>Abstract—</strong> Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. The clinical lesions are non-inflammatory open and closed comedones and or papules, pustules and nodules of varying degree of inflammation and depth. A lot of steroid, cosmetic and Ayurvedic products containing unlabeled depigmenting agent and steroids are available readily over the counter sale. The side effects of these products are not documented and can lead to adverse effects of continuous usage. This study was aimed to find out various offending depigmenting agents (topical unlabeled ste

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Donovan, Laura, Adela Joanta-Gomez, Julia Furnari, Brandi Mouton, and Andrew Lassman. "QOL-01. RISK FACTORS FOR AND CONSEQUENCES OF PROLONGED DEXAMETHASONE USE IN PATIENTS WITH GLIOBLASTOMA (GBM)." Neuro-Oncology 24, Supplement_7 (2022): vii240. http://dx.doi.org/10.1093/neuonc/noac209.929.

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Abstract BACKGROUND Dexamethasone is the primary treatment for tumor-associated edema. Prolonged use can have significant side effects and may negatively impact survival in GBM. Factors associated with steroid dependence and steroid associated side effects (SASEs) are not well established. METHODS We performed a retrospective study of patients with newly diagnosed, IDH-wildtype GBM at our center. Demographics, clinical and tumor characteristics, dexamethasone usage, and SASEs (infections, myopathy, hypertension, fractures, mood symptoms, weight gain, and hyperglycemia) were extracted through c

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Thebault, Simon, Hailey Bergman, Harold L. Atkins, Mark S. Freedman, and John Brooks. "CLIPPERS Responsive to Cladribine as a Durable Steroid-Sparing Agent." Neurology - Neuroimmunology Neuroinflammation 10, no. 1 (2022): e200060. http://dx.doi.org/10.1212/nxi.0000000000200060.

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ObjectiveWe report a case of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) who achieved durable and steroid-free remission after IV cladribine.MethodsA 25 year-old man presented with progressively worsening headaches, polydipsia, dysarthria, diplopia and vertigo, and obtundation requiring respiratory support. CSF revealed lymphocytosis, and MRI revealed a perivascular pattern of punctate enhancement involving the pons. An extensive workup for inflammatory, autoimmune, infective, and malignant explanations was unrevealing. He responded

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Choi, Young Sik, and Yo-Han Park. "Use of Steroid, Side Effects and Countermeasures." Journal of Clinical Otolaryngology Head and Neck Surgery 8, no. 1 (1997): 11–20. http://dx.doi.org/10.35420/jcohns.1997.8.1.11.

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Shephard, R. J. "Side Effects of Anabolic Androgenic Steroid Abuse." Yearbook of Sports Medicine 2009 (January 2009): 172–74. http://dx.doi.org/10.1016/s0162-0908(08)79335-8.

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KWASMAN, ALAN. "Steroid Abuse by Adolescents." Pediatrics 78, no. 1 (1986): 186. http://dx.doi.org/10.1542/peds.78.1.186.

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To the Editor.— I would like to call attention to my suspicion that there is significant steroid abuse among adolescents and offer a short case report. I have been surprised at the number of adolescent boys who come in for physical examinations and ask about steroids. None of these patients have asked for steroids, but they openly state that they can get them from "friends." All of them appear concerned about the side effects. I would like to present the salient features of one case of steroid abuse.

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Ahmed, Halawa. "Steroid withdrawal protocols in Renal Transplantation." Archives of Clinical Nephrology 4, no. 1 (2018): 001–8. https://doi.org/10.17352/acn.000029.

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Corticosteroid use as a component of immunosuppression protocol is widespread, even though their mechanisms of action are imprecise. The burden of metabolic side effects of steroids and the impact on quality of life in kidney allograft recipients has led to attempts in minimizing steroid exposure.

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GORAN, Loredana, Monica STATE, Ana NEGREANU, and Lucian NEGREANU. "Quality of Care in Inflammatory Bowel Disease: the Role of Steroid Assessment Tool (SAT) - a Review." Medicina Moderna - Modern Medicine 27, no. 3 (2020): 171–76. http://dx.doi.org/10.31689/rmm.2020.27.3.171.

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Corticosteroids have an important role in induction of remission in inflammatory bowel disease, but they are not an indicated for maintenance treatment as they are associated with many side effects. Despite new effi cient therapeutic options for maintaining remission, there is an excess in prescribing steroids in inflammatory bowel disease. Corticosteroid use was evaluated in international cohorts given that steroid free remission and avoiding serious side-effects of corticosteroids is a desirable goal. We discuss the role and the evidences on a secure web-based steroid assessment tool (SAT) w

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Aguayo, Juan Manuel Del Toro. "Side effects of steroid use in patients with traumatic spinal cord injury." Coluna/Columna 14, no. 1 (2015): 45–49. http://dx.doi.org/10.1590/s1808-1851201514010r127.

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OBJECTIVE: Indicate and identify potential complications in our unit associated with the use of steroids in patients over 16 years of age with traumatic acute spinal cord injury managed with NASCIS II, III scheme compared with patients with the same characteristics who did not receive this management. METHODS: To conduct a research study with reports of cases and controls in patients over 16 years of age and with an established diagnosis of acute spinal cord injury, treated definitively in our unit, performing the comparison of evolutionary process between those treated with steroids and those

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LEVINE, RICK. "Little Help from Article on Anaboiic Steroids." Pediatrics 87, no. 1 (1991): 123. http://dx.doi.org/10.1542/peds.87.1.123.

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To the Editor.— As a high school teacher I have been looking for guidance on preventing the abuse of anabolic steroids by our students. The article "Anabolic Steroid Use by Male Adolescents" by Johnson et al1 not only failed to provide this guidance, but the results failed to support the authors' conclusions. The study shows that, of the teenage users of steroids surveyed, 38% correctly identified liver disease, 35% cancer of the liver, and 30% stunted growth as side effects of steroid use.

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Dam, Jasmien, Florit Marcuse, Marc De Baets, and Catherine Cassiman. "Globe Subluxation following Long-Term High-Dose Steroid Treatment for Myasthenia Gravis." Case Reports in Ophthalmology 11, no. 3 (2020): 534–39. http://dx.doi.org/10.1159/000509527.

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This case report describes the unusual presentation of a globe subluxation following long-term high-dose oral steroid treatment for myasthenia gravis (MG). The patient presented initially with fluctuating vertical diplopia. Auto-antibodies against the acetylcholine receptor were weakly positive, confirming the diagnosis of MG. After initial treatment with pyridostigmine, the disease evolved to generalized MG. Plasmapheresis and high-dose steroids were started subsequently. As a side effect of this treatment the patient gained about 30 kg in weight and developed steroid myopathy and a prominent

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Ganesh, V., A. Banigo, A. E. L. McMurran, M. Shakeel, and B. Ram. "Does intranasal steroid spray technique affect side effects and compliance? Results of a patient survey." Journal of Laryngology & Otology 131, no. 11 (2017): 991–96. http://dx.doi.org/10.1017/s0022215117002080.

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AbstractBackground:Intranasal steroid sprays are fundamental in the medical management of inflammatory rhinological conditions. Side effects are common, but these may be related to the method of application rather than the medication itself.Methods:A survey was distributed to patients using intranasal steroid sprays at the ENT out-patient clinic at Aberdeen Royal Infirmary over three months. This evaluated the spray technique used, side effects and compliance.Results:Of 103 patients, 22 patients (21.4 per cent) reported side effects, including nasal irritation and epistaxis. Of the 20 patients

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Dalal, Preeti, Manisha Gulia, Monica Gupta, and Anita Tahlan. "Is dapsone still relevant in immune thrombocytopenia in resource limited settings?" BMJ Case Reports 12, no. 12 (2019): e232217. http://dx.doi.org/10.1136/bcr-2019-232217.

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Immune thrombocytopenia is an autoimmune disorder characterised by autoantibody production against platelets, increased platelet destruction and impaired thrombopoiesis. Steroids are the first-line agents whenever treatment is indicated; however, some patients may not respond and the responders may as well relapse while the dose is being tapered. Side effects of steroids prohibits their long-term use and patients often have to be switched to other agents. Standard drug management with intravenous immunoglobulins and thrombopoietin receptor analogues is difficult to administer in patients from

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Wardani, Indah Sapta. "Steroid Induced Diabetes Mellitus: An Overview." JURNAL SAINS TEKNOLOGI & LINGKUNGAN 9, no. 1 (2023): 206–13. http://dx.doi.org/10.29303/jstl.v9i1.441.

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Glucocorticoids are often used as immunosuppressant and anti-inflammatory therapy in various medical conditions. In addition to providing clinical benefits, glucocorticoids have various side effects, one of which is related to steroid-induced diabetes mellitus (SIDM). Steroid-induced diabetes mellitus can be a new onset or an exacerbation of hyperglycemia in patients who have previously been diagnosed with DM. Acute and chronic hyperglycemia due to steroids can have an impact on lengthening hospitalization, infectious complications, decreased response to therapy and increased mortality. The ch

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Okihara, Masaaki, Hironori Takeuchi, Yukiko Kikuchi, et al. "Individual Lymphocyte Sensitivity to Steroids as a Reliable Biomarker for Clinical Outcome after Steroid Withdrawal in Japanese Renal Transplantation." Journal of Clinical Medicine 10, no. 8 (2021): 1670. http://dx.doi.org/10.3390/jcm10081670.

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Recently, steroid reduction/withdrawal regimens have been attempted to minimize the side effects of steroids in renal transplantation. However, some recipients have experienced an increase/resumption of steroid administrations and acute graft rejection (AR). Therefore, we investigated the relationship between the individual lymphocyte sensitivity to steroids and the clinical outcome after steroid reduction/withdrawal. We cultured peripheral blood mononuclear cells (PBMCs) isolated from 24 recipients with concanavalin A (Con A) in the presence of methylprednisolone (MPSL) or cortisol (COR) for

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Carr, L., L. Mechtler, L. Recht, et al. "The effect of corticorelin acetate on peritumoral brain edema: An interim report of an open-label study as part of a phase III program." Journal of Clinical Oncology 25, no. 18_suppl (2007): 9095. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9095.

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9095 Background: Steroid treatment of peritumoral brain edema (PBE) in patients with malignant brain tumors (BTs) is frequently associated with debilitating steroid side effects. The investigational agent corticorelin acetate injection, a synthetic peptide identical to h-corticotropin-releasing factor (hCRF), compared favorably to dexamethasone in reducing PBE in animal models of primary or metastatic BT. Toxicology and clinical studies including a pilot study in patients with malignant BTs published in ASCO's Annual Meeting Proceedings, showed hCRF to be safe and virtually devoid of steroid s

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Horwitz, H., J. T. Andersen, and K. P. Dalhoff. "Health consequences of androgenic anabolic steroid use." Journal of Internal Medicine 285, no. 3 (2018): 333–40. https://doi.org/10.1111/joim.12850.

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Background The lifetime prevalence of androgenic anabolic steroid abuse is estimated to be around 6% for men, but there is limited knowledge about the side effects of these drugs. Objective To investigate mortality and morbidity amongst users of androgenic anabolic steroids (AAS). Methods In this retrospective matched cohort study, 545 male subjects tested positive for AAS in Danish fitness centres during the period 3 January 2006 to 1 March 2018. Subjects were matched with 5450 male controls. In addition, 644 men who were sanctioned because they refused to submit to a doping test and 6440 con

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Williamson, IJ, SP Matusiewicz, PH Brown, AP Greening, and GK Crompton. "Frequency of voice problems and cough in patients using pressurized aerosol inhaled steroid preparations." European Respiratory Journal 8, no. 4 (1995): 590–92. http://dx.doi.org/10.1183/09031936.95.08040590.

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The aim of the study was to assess the prevalence of throat and voice symptoms in asthma patients using pressurized aerosol, metered-dose, inhaled corticosteroid preparations. A questionnaire was administered to hospital out-patients in an asthma clinic and to a control group attending a diabetic clinic. Two hundred and fifty five consecutive out-patients using pressurized aerosol inhaled corticosteroids and 100 controls were surveyed. One hundred and forty seven (58%) patients taking inhaled steroids reported voice dysphonia or throat symptoms compared with 13% of control patients. Women admi

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David Smith and Venu Sen. "The Toxicity of Corticosteroids." International Healthcare Research Journal 5, no. 10 (2022): RV5—RV9. http://dx.doi.org/10.26440/ihrj/0510.01498.

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Minimization of steroid therapy has always been one of the main objectives of immunosuppressive protocols after kidney transplantation, due to numerous side effects. The use of a further reduced daily dose of steroids is considered by many to be a fair compromise between toxicity and efficacy. Unfortunately, the great inter-individual variability of the pharmacokinetics of steroids does not prevent the appearance of major side effects in a variable percentage of patients, even with the low dose used. A drug interaction between steroids and drugs used after transplantation can also contribute t

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Tebulo, Kintuza Lumwako. "Therapeutic Potential of Citrus Flavonoids in Metabolic Inflammation and Insulin Resistance." Research Output Journal of Engineering and Scientific Research 4, no. 3 (2025): 60–64. https://doi.org/10.59298/rojesr/2025/4.3.6064.

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The prescription and use of steroids, both corticosteroids and anabolic steroids, present significant ethical challenges in medical practice. While corticosteroids are integral in managing inflammatory conditions, their long-term use is associated with considerable side effects, necessitating careful medical supervision. Anabolic steroids, originally developed for medical purposes, are often misused for performance enhancement, raising concerns about health risks, fairness in sports, and informed consent. This review explores the ethical implications of steroid prescriptions, focusing on the b

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Miranda Ruiz, E., E. Marimon Muñoz, J. Ramirez Gonzalez, et al. "Acute psychosis following corticosteroid administration for COVID-19 and Respiratory Syncytial Virus infection: A case study." European Psychiatry 66, S1 (2023): S790. http://dx.doi.org/10.1192/j.eurpsy.2023.1668.

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IntroductionSteroids are a necessary treatment for hypoxic respiratory failure; however there are many side effects that should be taken into account. A 44- year-old-woman with asthma and no past psychiatric history was admitted due to COVID-19 pneumonia and Respiratory syncytial virus (RSV) infection, presenting hypoxic respiratory failure. After two days of intravenous methylprednisolone administration, the patient presented acute psychosis and agitation.It has been previously described that steroid use can cause effects such as mania, anxiety, agitation, delirium and psychosis amongst other

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Woolcock, AJ. "Steroid resistant asthma: what is the clinical definition?" European Respiratory Journal 6, no. 5 (1993): 743–47. http://dx.doi.org/10.1183/09031936.93.06050743.

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Asthma is usually a steroid responsive disease. A few patients respond poorly to these drugs, and others need such high doses to control the disease that side-effects become a serious problem. The term steroid resistant asthma is used for both groups. In some patients, factors may be operating to make the asthma worse and, thus, to increase the requirement for steroids. In order to make a clinical diagnosis of steroid resistant asthma, it is therefore necessary to investigate the factors that could be operating to prevent a "normal" response to steroids. These factors include wrong diagnosis,

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Barkan, R., L. Shpoker, R. Abboud, et al. "P553 Factors related to steroid consumption in IBD patients: Evidence from a multicenter Study." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S519—S520. http://dx.doi.org/10.1093/ecco-jcc/jjab076.674.

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Abstract Background Steroids are frequently used to induce remission in inflammatory bowel disease (IBD) but should not be used as maintenance treatment. Understanding the factors related to steroid consumption is essential in order to avoid over prescription of these drugs. Methods A cross-sectional study was conducted between 2019 and 2020 in six medical centers in Israel. Data was collected using a structured self-administered tool containing the following: socio demographic and clinical characteristics, knowledge of side effects and complications of steroid treatment, self-care and complia

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Dinn, Gemma. "Steroid-induced diabetes in cancer patients." Journal of Prescribing Practice 1, no. 12 (2019): 610–15. http://dx.doi.org/10.12968/jprp.2019.1.12.610.

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Cancer and its treatments commonly require steroids to manage their side effects. Steroids increase blood glucose levels, causing new hyperglycaemia in patients with no known history of diabetes, termed steroid-induced diabetes mellitus (SIDM). This paper explores SIDM in cancer patients, identifying areas that could influence positive changes in current and future practice in its management and discuss their impact on practice in an outpatient setting. This paper concludes that active encouragement from staff can lead to an improved patient experience, as well as developing patient-led decisi

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Adams, Rebecca W., Robin L. Chapman, and Gregory A. Smallwood. "Steroid Withdrawal in Liver Transplant Recipients." Progress in Transplantation 11, no. 3 (2001): 217–23. http://dx.doi.org/10.1177/152692480101100312.

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Because of troublesome side effects associated with steroid use, many transplant centers have tried to withdraw steroids from stable, solid organ transplant recipients. The objective of this study was to evaluate the ability to wean liver transplant recipients off steroids, depending on both their primary immunosuppressive regimen and their primary disease state. This was a retrospective, single-center review of steroid weaning in adult orthotopic liver transplant recipients. Based on primary immunosuppression, patients could be weaned off steroids similarly if they were taking cyclosporine or

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Ajith, Gayathri, Saravana Bhava, Rajesh Kannan, and Bala Subramaniam. "Corticosteroid-induced Glaucoma: An avoidable blindness." Indian Journal of Clinical and Experimental Ophthalmology 10, no. 3 (2024): 408–14. http://dx.doi.org/10.18231/j.ijceo.2024.072.

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Healthcare professionals frequently advise the use of topical steroid eye drops to manage and control postoperative inflammation following phacoemulsification. Although there are many benefits associated with steroid usage, it is imperative to recognize the potential negative repercussions that may arise. In individuals who respond to steroids, the use of topical steroid drops can lead to an increase in intraocular pressure (IOP). Increase in IOP resulting from the side effects of steroids typically manifests several weeks following the initiation of eye drop therapy. The first documentation o

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Shermon, Suzanna. "Neuropsychiatric Side Effects After Lumbosacral Epidural Steroid Injections: A Prospective Cohort Study." Pain Physician Journal 27, no. 3 (2024): 149–59. https://doi.org/10.36076/ppj.2024.7.149.

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BACKGROUND: The central nervous system contains steroid receptors, particularly in the hypothalamic and limbic systems. These systems are responsible for driving certain emotions in humans, especially stress, anxiety, motivation, energy levels, and mood. Thus, corticosteroids may precipitate patients to experience these emotions. Most existing studies report neuropsychiatric side effects after oral or intravenous corticosteroids rather than epidural. OBJECTIVES: This study examines the neuropsychiatric side effects after epidural steroid injections (ESIs), with a focus on whether certain facto

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Akbari, Mitra. "Efficacy of Topical Tacrolimus 0.05% Suspension in Steroid-Resistant and Steroid-Dependent Vernal Keratoconjunctivitis." Pakistan Journal of Medical and Health Sciences 15, no. 7 (2021): 2150–55. http://dx.doi.org/10.53350/pjmhs211572150.

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Objective: The purpose of this study was to investigate the safety and effectiveness of topical tacrolimus 0.05% suspension in the management of prolonged steroid-dependent and -resistant vernal keratoconjunctivitis (VKC). Materials and methods: The present interventional prospective case series were conducted on the research units suffering from refractory VKC between 2017, April and 2020, December. Despite routine drug treatment, consisting of topical steroids (steroid-resistant group), all subjects exhibited active symptomatic illness or were dependent on topical steroids (steroid-dependent

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Travis, Simon. "How do you avoid and treat steroid side effects?" Inflammatory Bowel Diseases 14, Supplement (2008): S214—S215. http://dx.doi.org/10.1097/00054725-200810001-00101.

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Cicala, Roger S., Laura Westbrook, and John J. Angel. "Side effects and complications of cervical epidural steroid injections." Journal of Pain and Symptom Management 4, no. 2 (1989): 64–66. http://dx.doi.org/10.1016/0885-3924(89)90024-9.

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Travis, Simon. "How do you avoid and treat steroid side effects?" Inflammatory Bowel Diseases 14 (October 2008): S214—S215. http://dx.doi.org/10.1002/ibd.20649.

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Oberholzer, José, Mohammed Al-Saghier, and Norman M. Kneteman. "Steroid Avoidance in Liver Transplantation." Canadian Journal of Gastroenterology 18, suppl c (2004): 5C—11C. http://dx.doi.org/10.1155/2004/412135.

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Corticosteroids have always played a valuable role in transplantation. Unfortunately, they are subject to a wide range of side effects, such as hyperlipidemia, hypertension, diabetes mellitus, osteoporosis, growth retardation and Cushingoid appearance. Steroids may also exacerbate problems that existed before surgery, including malignancy, hepatitis B and hepatitis C. New, powerful immunosuppressants have allowed steroid use to be reduced or avoided altogether, but use of these regimens is not simple and may be associated with late acute rejection and recurrence of autoimmune disease. The pres

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Manchikanti, Laxmaiah. "Steroid Distancing in Interventional Pain Management During COVID-19 and Beyond: Safe, Effective and Practical Approach." Pain Physician 4S;23, no. 8;4S (2020): S319—S350. http://dx.doi.org/10.36076/ppj.2020/23/s319.

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Background: Since the late 1940s, corticosteroids have been a mainstay class of agents in multiple interventional techniques and intra-articular injections. Exogenous glucocorticoids are structurally and pharmacologically similar to the endogenous hormones. As such, multiple actions of corticosteroids are exhibited, including those of anti-inflammatory and immunosuppressive effects. Epidural injections, with or without steroids, have been extensively used throughout the world. There are reports of epidural injections starting in 1901, with steroids being added to the local anesthetic since 195

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Ashraf, Soliman, De Sanctis Vincenzo, Yassin Mohamed, et al. "The potential benefits and risks of sex-steroids therapy in thalassemic patients with hypogonadism." World Journal of Advanced Research and Reviews 18, no. 2 (2023): 1063–73. https://doi.org/10.5281/zenodo.8413978.

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<strong>Introduction</strong>: A recent review from 14 Mediterranean and Middle East countries (n =4477, mean age = 16.5 years) showed that the pooled prevalence of delayed puberty / hypogonadism in patients with BTM was   45.6%. Studying the consequences of hypogonadism and the potential benefits versus unwanted side effects of sex-steroid hormone replacement therapy (HRT) in children and adolescents with Beta Thalassemia Major (BTM) represent an important issue for these patients. <strong>Objectives</strong>: We reviewed the literature (Pubmed, Google scholar, Scopus, Research gate

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Rosalia Adriani Malika and Lydia Nuradianti. "Bilateral Steroid Induced Glaucoma In A 10-year-old Boy." Asian Journal of Health Research 2, no. 2 (2023): 55–59. http://dx.doi.org/10.55561/ajhr.v2i2.97.

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Introduction: Topical steroids are used in the treatment of various ocular disorders. However, it can cause numerous side effects. Steroid-induced glaucoma is the most severe complication of the unmonitored use of steroids. It is diagnosed by visual field defects, increased intraocular pressure (IOP), and glaucomatous optic neuropathy (GON) due to prolonged usage of steroids. Case Presentation: a 10-year-old boy presented to the outpatient clinic in Undaan Eye Hospital complaining of headache, re dness and itchiness in both eyes. He started using dexamethasone 0.1% eye drops without a physicia

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Arsalan, Zahra, Omer Zafar, Syed Abid Hassan Naqvi, and Qurat Ul Ain. "EFFECTIVENESS OF STEROIDS VERSUS IMMUNOMODULATORS INTREATMENT OF VERNAL KERATO-CONJUNCTIVITIS. A STUDY AT ARMED FORCES INSTITUTE OF OPHTHALMOLOGY." PAFMJ 71, no. 6 (2021): 2045–48. http://dx.doi.org/10.51253/pafmj.v6i6.5144.

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Objective: To evaluate whether steroids or immunomodulator is a better mode of treatment in long term management of vernal keratoconjunctivitis.Study Design: A quasi experimental study. Place and Duration of Study: Armed Forces institute of Ophthalmology, Rawalpindi, from Feb 2019 to Oct 2019. Methodology: Ninety-two patients in between ages of 5-20 years were divided into two equal groups of 46 patients each. After instillation of 0.1% Fluoromethalone (steroid) into both eyes of patients of vernal keratoconjunctivitis, in group A and outcomes were compared with those of 0.05% Cycl

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Braughler, J. Mark, and Edward D. Hall. "Current application of “high-dose” steroid therapy for CNS injury." Journal of Neurosurgery 62, no. 6 (1985): 806–10. http://dx.doi.org/10.3171/jns.1985.62.6.0806.

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✓ Although administration of glucocorticoid steroids is one of the most widely used therapeutic modalities for the clinical management of acute trauma of the central nervous system (CNS), controversy continues regarding their effectiveness. In essence, two viewpoints concerning their use exist. Some believe that despite their poor clinical record, the steroids nevertheless have a place in the treatment of human CNS trauma. In general, this group of clinical investigators uses the steroids primarily out of tradition, feeling that steroid therapy may be of some benefit. Unfortunately, confusion

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La, Jessica, Victoria Hurwitz, Charlotte Robinson, et al. "SHOULD CALCIUM SUPPLEMENTS BE PRESCRIBED PROPHYLACTICALLY FOR PATIENTS DIAGNOSED WITH A HIGH-GRADE GLIOMA (HGG) ON PROLONGED STEROID USE?" Neuro-Oncology 25, Supplement_3 (2023): iii20. http://dx.doi.org/10.1093/neuonc/noad147.085.

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Abstract AIMS The case study review will evaluate whether patients on long term steroid would benefit from calcium supplements and if a protocol for a bone density scan should be in place in relation to how long patients have been on steroids for. Duration of steroid use increases patients’ risk to steroid related toxicity when taken more than 3 weeks. These can include endocrine, skeletal and psychiatric side effects amongst many others. It is therefore important to assess how we can improve patients’ quality of life (QOL) with limited prognosis. METHOD In a single centre, patients diagnosed

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Biswas, Rabindranath, Dibyajyoti Sarkar, and Loknath Ghoshal. "Normal saline infiltration as a treatment of steroid injection induced tissue atrophy: A clinical study." Biomedicine 43, no. 5 (2023): 1472–75. http://dx.doi.org/10.51248/.v43i5.2719.

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Introduction and Aim: Intramuscular steroid injection is a technique often used by unqualified village practitioners to control symptoms of a variety of disease processes. Such injudicious use of high dosages of steroids results in local side effects. Such side effects include occurrence of tissue atrophy at the site of injection. The treatment of such tissue atrophy includes filling up the gap with injection of autologous fat and other materials. However, these are expensive and require specialised set up. Normal saline infiltration into the atrophic area at varying intervals has been success

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Jung, Seon Min, Jin Hye Kwak, Moo Keon Kim, Kyung Tae, Seok Hyun Cho, and Jin Hyeok Jeong. "The Long-Term Effects of Budesonide Nasal Irrigation in Chronic Rhinosinusitis with Asthma." Journal of Clinical Medicine 11, no. 10 (2022): 2690. http://dx.doi.org/10.3390/jcm11102690.

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Chronic rhinosinusitis with nasal polyps (CRSwNP) in asthmatic patients has a high recurrence rate even after surgery. For this reason, oral steroids are frequently used, but their long-term use may cause side effects. The purpose of this study is to investigate the long-term effects of budesonide nasal irrigation (BNI) in CRSwNP and asthma. An analysis of 33 patients with CRSwNP and well-controlled asthma, who performed BNI for more than 12 months, was performed. We compared oral steroid and antibiotic dosages as well as nasal endoscopy scores before, and every six months after, BNI. The six-

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