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1
Sachinkumar, Sahebrao Patil, and Annasaheb Sable Arjun. "A Review on effectiveness of Guggulu in treatment of obesity." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 707–12. https://doi.org/10.5281/zenodo.7787694.
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Obesity is not because it runs in the family; it is because the lifestyle and concept responsible for the people turn obese. <em>Sthaulya</em> has been included by <em>Acharya Charak</em> among <em>Ashtauninditiya Purusha</em>. Obesity has become epidemic today and it is essential to understand the consequences of obesity. In a world where food supplies are intermittent, fat cells, residing within widely distributed adipose tissue depots, are adapted to store excess energy efficiently as triglyceride and, when needed, release stored energy as free fatty acids for use at other sites. This physiologic system, orchestrated through endocrine and neural pathways, permits humans to survive starvation for as long as several months. Recent study reveals that obesity and its related disorders occupying major share in the spectrum of health, disease and management. It is one of the disorders of non-communicable disease, which has laid down foundation stone of diabetes mellitus, metabolic syndrome, hypertension and others.The aetio-pathogenesis, management and consequences of obesity are not very clear and it is still evolving in biomedical sciences. As a disease entity it is a multi-factorial metabolic disorders, very near to <em>Medoroga</em>/<em>Sthaulya</em> of <em>Ayurveda</em>.The prevalence of obesity is higher in urban areas than in rural populations of India, due to a steady erosion of the holistic way of life in the cities as well as the sedentary and overeating habit. The spiritual, psychological, and physical levels of human health and disease is given due importance in <em>Ayurveda</em>. The current understanding of adipose tissue as an endocrine organ coupled with the core principles drawn from Ayurveda may form a scientific basis for the management of obesity. <em>Guggulu</em> is one of the oldest <em>Ayurvedic</em> herbs taken orally for a variety of diseases. The term “<em>Guggul</em>” in Sanskrit means “protects against diseases. In course of the management of obesity <em>Guggulu</em> is a popular herbal drug which has been used as single form or compound form to treat several ailments since a long time in India. The oleo-gum or the resin of <em>Guggulu</em>obtained from stem is the main part, which has been used for therapeutic uses.
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Sachinkumar Sahebrao Patil and Arjun Annasaheb Sable. "A Review on effectiveness of Guggulu in treatment of obesity." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 707–12. http://dx.doi.org/10.30574/wjarr.2022.16.2.1183.
Full textAbstract:
Obesity is not because it runs in the family; it is because the lifestyle and concept responsible for the people turn obese. Sthaulya has been included by Acharya Charak among Ashtauninditiya Purusha. Obesity has become epidemic today and it is essential to understand the consequences of obesity. In a world where food supplies are intermittent, fat cells, residing within widely distributed adipose tissue depots, are adapted to store excess energy efficiently as triglyceride and, when needed, release stored energy as free fatty acids for use at other sites. This physiologic system, orchestrated through endocrine and neural pathways, permits humans to survive starvation for as long as several months. Recent study reveals that obesity and its related disorders occupying major share in the spectrum of health, disease and management. It is one of the disorders of non-communicable disease, which has laid down foundation stone of diabetes mellitus, metabolic syndrome, hypertension and others.The aetio-pathogenesis, management and consequences of obesity are not very clear and it is still evolving in biomedical sciences. As a disease entity it is a multi-factorial metabolic disorders, very near to Medoroga/Sthaulya of Ayurveda.The prevalence of obesity is higher in urban areas than in rural populations of India, due to a steady erosion of the holistic way of life in the cities as well as the sedentary and overeating habit. The spiritual, psychological, and physical levels of human health and disease is given due importance in Ayurveda. The current understanding of adipose tissue as an endocrine organ coupled with the core principles drawn from Ayurveda may form a scientific basis for the management of obesity. Guggulu is one of the oldest Ayurvedic herbs taken orally for a variety of diseases. The term “Guggul” in Sanskrit means “protects against diseases. In course of the management of obesity Guggulu is a popular herbal drug which has been used as single form or compound form to treat several ailments since a long time in India. The oleo-gum or the resin of Gugguluobtained from stem is the main part, which has been used for therapeutic uses.
3
Aggarwal, Monica, and Sujata Yadav. "A COMPARATIVE STUDY ON THE EFFECT OF DASHANG GUGGULU AND BILVADI KWATH IN THE MANAGEMENT OF STHAULYA WITH REFERENCE TO OBESITY." International Journal of Research in Ayurveda and Pharmacy 14, no. 1 (2023): 33–38. http://dx.doi.org/10.7897/2277-4343.14019.
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Introduction: Obesity results from excess calorie consumption and reduced physical activity in a person. Obesity is the commonest lifestyle disorder in the present urbanized world and is the 5th leading cause of global death and 2nd preventable cause of death next to smoking. Objective: to evaluate the clinical efficacy of Dashang Guggulu and Bilvadi Kwath in the management of Sthaulya. Methods and Materials: After approval from the IEC committee, an interventional study was carried out on obese individuals for three months by giving in 2 drugs in different groups, namely Dashang Guggulu and Bilvadi Kwath, comparing it with a third placebo group. Patients were evaluated on subjective parameters, anthropometric measurements, and lipid profile values. Result: On inter-group comparison, Bilvadi Kwath showed results in reducing body measurements like body weight and BMI. No changes in subjective symptoms except Javoparodha symptoms (loss of enthusiasm) and lipid profile were noted. Conclusion: Bilvadi Kwath was found to be more effective than Dashang Guggulu.
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Joshi, Twinkle, Vaishali Kuchewar, and Aman Chhabra. "Efficacy of Medohar Arka in Sthaulya (Overweight) – A single blind placebo controlled clinical study." International Journal of Ayurvedic Medicine 15, no. 2 (2024): 437–43. http://dx.doi.org/10.47552/ijam.v15i2.4503.
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In Ayurveda, Sthaulya is santarpanothha vyadhi caused by excessive accumulation of Meda resulting in pendulous appearance of Sphik, Udara and Stana. It can be correlated with overweight or obesity. Obesity is characterized by abnormal growth of adipose tissue due to enlargement of fat cell size or number which is expressed in BMI, 24.9 kg/m2 to 29.9 kg/m2 indicates overweight and >30 kg/m2 indicates obesity. Studies have been conducted on medications like medohar guggulu, navaka guggulu but Medohar Arka was relatively unexplored. It is a low cost medicine described by Ras Tantra Saara and Siddha Prayoga Sangraha for sthaulya. Material and Methods-Study comprised of 66 participants between age group of 20-50 years, either sex, having B.M.I. between 25-30 kg/m2. Group M was treated with Medohar Arka 15ml twice daily before food with equal amount of water whereas Group P was treated with Placebo 250 mg twice daily before food with equal amount water for 90 days. Pathyapathya and vyayama was advised to both groups in the form of Ahar (Diet) and Vihar(30 min brisk walk). Assessment was done on day 0 and day 90 (completion of treatment). Participants were assessed for objective parameters like Body Mass Index, Waist Hip Ratio(WHR) and Mid Arm circumference(MAC). On comparing both the groups, statistically significant improvement was observed in Body Mass Index, Waist Hip Ratio, Mid Arm circumference in Medohar arka group. Conclusion- Medohar Arka was effective in managing overweight. Further study could be conducted on obese patients for generalized use of this medicine.
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Kulkarni, Dr Pushkaraj, and Dr Ajay Deshmukh. "“A CLINICAL STUDY TO EVALUATE THE EFFECT OF DASHAANG GUGGUL ON STHOULYA W.S.R TO OBESITY." Sanjeevani Darshan National - Journal of Ayurveda & Yoga 01, no. 02 (2023): 161–66. http://dx.doi.org/10.55552/sdnjay.2023.1218.
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In Modern days inappropriate food habit is the main cause of Sthaulya ( obesity) .It occurs as a result of sedentary lifestyle,unhealthy eating habits, lack of physical activity , mental stress and other Factors. Obesity is becoming more common in both children and adults every day .Obesity is associated with many medical illnesses like ( hypertension atherosclerosis and diabetes). Aims and Objective : To clinical study to evaluate the effect of Dashaang Guggul on Sthaulya.Material and Methods : Self made Dashaang Guggul tablet of weight 1 gm Results and conclusion: Conclusion will be drawn strictly on the basis of statistical analysis at the final stage of study.
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Yadav, Kapil Deo. "Sahaj Vati in the Management of Obesity (Sthaulya): A Single-arm Clinical Trial." Indian Journal of Ayurveda and Integrative Medicine KLEU 5, no. 1 (2024): 31–35. http://dx.doi.org/10.4103/ijaim.ijaim_45_22.
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ABSTRACT Background: Obesity is the leading cause of death and disabilities around the world with burdens expected to increase and predict that the global economic impact will reach $4.32 trillion annually by 2035. Aim and Objective: To assess the effectiveness of Sahaj Vati in reduction of body weight and body mass index in obese persons. Materials and Methods: Sahaj Vati, herbomineral formulation, consists of Shilajeet and Guggul (Commiphora mukul), Chitrak (Plumbago zeylanica), Haridra (Curcuma longa Linn), and Agnimatha (Clerodendrum phlomidis Linn) is explored for the possible management of obesity. The study is a single arm with pre and post-test design, among the 44 patients screened, 30 patients meeting the criteria were enrolled in the study. Sahaj Vati was administered in 2 g/day in divided doses with water after meals for 3 months. Result: The study showed significant reduction in body mass (P < 0.001) and body mass index (P < 0.001), cholesterol (P < 0.001), and triglycerides (P < 0.001) along with significant enhancement in high-density lipoprotein (P < 0.01). Conclusion: Sahaja vati is effective in the reduction of body weight. The finding of the present study is encouraging and may have a beneficial role in obesity.
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Santosh I. Swami and Payal Vilas Chavat. "To Evaluate Combined Efficacy of Amrutadya Guggulu and Udvartana followed by Bashpa Sweda in the Management of Sthaulya." International Journal of Ayurveda and Pharma Research, October 20, 2024, 47–55. http://dx.doi.org/10.47070/ijapr.v12i9.3382.
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Obesity (Sthaulya) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle disorders like Diabetes mellitus (T2DM), Coronary Heart Disease (CHD), hypertension. In Ayurveda, Sthaulya (obesity) is regarded as Medoroga, a disorder of Meda Dhatu which includes fat tissue and fat metabolism. In Ayurveda Sthaulya is regarded as Medoroga. In Sthaulya Meda causes obstruction all Strotasa which leads to of Koshthasthit Saman Vayu Vriddhi, which in turn causes Jatharagnivardhana. It leads to Medadhatvagni Mandya and augmentation of Meda which results in Chalaspika, Chalaudara, Chala stana. According to WHO World Health Statistics Report 2012, globally one in 6 adults are obese and nearly 2.8 million individuals die each year due to overweight. Amrutadya Guggulu shows Rasa-Katu, Tikta, Kashaya, Guna-Laghu, Ruksha and Virya-Ushna, Vipaka-Katu, Dosha, Karma-Kapha Vatashamaka is effective in the management of Sthaulya. The ingredients of Udvartana Triphala (Kaphahara, Deepan), Musta, Darvi, Devdaru are Tikta, Kashay, Laghu, Ruksha Gunatamak having Sthaulyahara property. Bashpa Sweda given after Udvartana will make Vilayana of Vikruta meda. Due to this property, it breaks the Samprapti of Sthaulya. Hence the present attempt is done to encompass the upto date comprehensive literature to study the mode of action of Amrutadya Guggulu and Udvartna followed by Bashpa Sweda in the management of Sthaulya w.s.r. to Ayurvedic properties. Total 40 patients were enrolled in this study, significant result was seen in all subjective criteria, also 4 to 4.5kg weight loss is seen in all patients. For statistical analysis paired student ‘t’ test, Wilcoxon test were used.
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Alodaria, Nirmal P., Gupta S. N, Dhaval Dholakiya, and Kaushik B. Vyas. "Ayurvedic Panchkarma Management of Sthaulya (Obesity): A Case Report." International Journal of Ayurvedic Medicine 8, no. 3 (2017). http://dx.doi.org/10.47552/ijam.v8i3.960.
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Obesity is burning health problem for society nowadays. In Charak Samhita, Sthaulya is described widely and with deep interpretation. Also in sutrasthana which is most important part of Charak Samhita, in different adhyaya (eg. Astauninditiya, Langhanabrumhaniya, Santarpaniya) causes, symptoms and treatment are described. As an alternative approach, Ayurvedic treatment may serve as promising modality.A 27 years old male patient came in P.D. Patel Ayurveda Hospital at 5th June 2015. Patient measured weight was 98.1 kg and BMI was 33.94 which is fairly included in obesity category according to NHI guidelines. He also had some associated complaints like exertional dyspnoea, increased appetite, excessive perspiration. He was admitted in hospital and was treated with Snehana ( Aabhyantara and Bahya ), Swedana,Vamana, Virechana, Niruha Basti, Udavrtana along with oral medicines like Varunaadi Kwatha, Arogyavardhini Vati, Triphala Guggulu, Kaishor Guggulu and Navayasa Lauha. Also patient was advised to follow prescribed dietary regimes and life style strictly. The patient responded very well. He lost about 10.2 kg of weight, which was 87.9 kgs and BMI was 30.41 only in 26 days without any complications and any signs and symptoms of malnutrition. So with the help of Ayurvedic management patient got weight loss significantly
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Alodaria, Nirmal P., S. N. Gupta, Dhaval Dholakiya, and Kaushik B. Vyas. "Ayurvedic Management of Sthaulya (Obesity): A Case Report." Journal of Ayurveda and Integrated Medical Sciences (JAIMS) 2, no. 4 (2017). http://dx.doi.org/10.21760/jaims.v2i4.9383.
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Obesity is burning health issue for society nowadays. In Sutrasthana of Charaka Samhita, in different Adhyaya (eg. Astauninditiya, Langhanabrumhaniya, Santarpaniya) causes, symptoms and treatment of Sthaulya are described. As an alternative approach, Ayurvedic treatment may serve as promising modality. A 17 years old male patient came in P.D. Patel Ayurveda Hospital on 22th May 2017. Patients weight was 114.8 kg and BMI was 37.51 which fairly included in obesity category according to NHI guidelines. He also had some associated complaints like exertional dyspnoea, increased appetite, excessive perspiration. He was treated with Snehana (Aabhyantara and Bahya), Swedana, Vamana, Virechana, Niruha Basti, Udvartana along with oral medicines like Varunaadi Kwatha, Arogyavardhini Vati, Triphala Guggulu, and Navayasa Lauha along with prescribed dietary regimes and life style modification. He lost about 9.7 kg of weight, which was 105.1 kgs and BMI was 34.34 only in 26 days without any complications.
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Zala, Divya, Dilip Prajapati, Anup Thakar, Harisha CR, and V.J.Shukla. "PHARMACOGNOSTICAL, PHYSICOCHEMICAL AND HPTLC EVALUATION OF AMRUTADHYA GUGGULU A POLYHERBAL FORMULATION FOR PHARMACEUTICAL STANDARDIZATION." Journal of Biomedical and Pharmaceutical Research 9, no. 1 (2020). http://dx.doi.org/10.32553/jbpr.v9i1.721.
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Background: Standardization of herbal formulation is needed in order to assess of quality of drug. Maintaining the quality standard of a polyherbal formulation is a difficult task. In the era of increasing demand for traditional medicines, maintaining quality standards is the need of the hour.
 Aim: The present work was carried out to standardize the finished product Amrutadhya Guggulu to confirm its identity, quality and purity.
 Material and Method: Amrutadhya Guggulu is mentioned in the treatment of Sthaulya (Obesity), and it was prepared according to the method as described in Chakradatta. Amrutadhya Guggulu powder was evaluated for its pharmacognostic and pharmaceutical analysis. It contains drug like Guduchi, Ela, Kutaja Phala, Kutaj twaka etc.
 Result: Epicarp and stone cell of Vidanga, silica deposition of Amalaki, oil globule of Ela etc were the characteristic features observed in the microscopy of Amrutadhya Guggulu powder .Results found in pharmaceutical parameters of Amrutadhya Guggulu powder like Loss on drying8.07% w/w, Ash value 3.07% w/w, Water soluble extract 22.5 % w/w, alcohol soluble extract 13.44%w/w and pH 4
 Conclusion: The Obtained values of all parameters for the finish product can be adopted to set down new standards.
 Keywords: Amrutadhya Guggulu, HPTLC, Pharmacognostical, Pharmaceutical analysis
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Kumar Singhal, Harish. "Clinical Study on Dashanga Guggulu and Surya Namaskar in the Management of Sthaulya (Obesity) In Children." Orthopedics and Rheumatology Open Access Journal 22, no. 2 (2023). http://dx.doi.org/10.19080/oroaj.2023.22.556083.
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Introduction: One of the oldest medicinal sciences in the world is Ayurveda. It describes the conceptual analysis of various diseases using its own principles and methodologies. Distinct Acharya has given different descriptions of “Sthoulya” in Ayurveda. In Ayurveda terms, Sthoulya is used as overweight and obesity. Obesity is defined as an overabundance of adipose tissue-fat depot in the body. This study has undertaken the management of Sthoulya by assessing the comparative efficacy of Dashanga Guggulu and Surya Namaskar in the management of Sthoulya (childhood obesity). The available data is based on clinical findings.
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Shikha Chaudhary and Parshant Minhas. "Appraisal of Kalp Chikitsa in the Management of Grade II Obesity: A Case Report." International Journal of Ayurveda and Pharma Research, January 16, 2022, 24–27. http://dx.doi.org/10.47070/ijapr.v9i12.2113.
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Obesity is a great concern for one and all. Its increasing rate in developing country leading to epidemic as the dietary habits of Asians have been westernized rapidly in past few years. The present case report evaluates the efficacy of Medohar guggulu kalp chikitsa in obese patient. A 49 years old man came with complaint of increase weight from last 3 years and pain in bilateral knee joints for 6 months. Though Ayurveda advocates the different modalities of treatment in Obesity viz., Sthaulya. In present case, Kalp chikitsa with Medohar guggulu was administered to patient for 10 days followed by structured diet for another 10 days. The patient responded well to prescribed treatment and effective results were achieved. Patient lost 9.5kg of weight in 20 days without any complications. This unique ancient modality of treatment could be boon for managing lifestyle disorders and also to reprieve the ill effects of condition in long term
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Triveni Raina and Dalip Sharma. "A Clinical and Laboratory Profile of Sthaulya W.S.R to Obesity and its Management by Amritadya Guggulu." International Journal of Ayurveda and Pharma Research, March 6, 2022, 6–16. http://dx.doi.org/10.47070/ijapr.v10i2.2289.
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In Ayurveda, it is regarded as Medoroga which includes fat tissue and fat metabolism, results from the excessive accumulation of Meda (fat/ adipose tissue) and Mamsa (flesh/ muscle tissue) leading to flabbiness of hips, abdomen, and breast. It is considered as Santarpanottha Vikara and counted one among the Ashtnindita Purusha by Ayurvedic Acharayas. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as Sthoulya. It is most prevailing condition being faced by majority of the population, but yet among the most neglected health problem in the world. In this regard approach of this study is to give safer, comprehensive and rational option for treating Sthaulya (Obesity) and this is a humble attempt to probe into the different pathophysiological aspects behind Sthaulya, taking into consideration the classical therapy coupled with modern interpretations. Amritadya Guggulu by the virtue of its Rasapanchaka (Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka) is effective in the management of Sthoulya including all Kapha predominant pathologies, leading to Samprapti Vigatana of Sthoulya. Hence this study is carried out to establish the efficacy of the treatment considering the clinical and laboratory profile of obesity (Sthoulya). The study was done on 30 patients taken from both IPD & OPD of RGGPG Ayurvedic College and Hospital, Paprola, H.P. The duration of the trial was 60 days with follow up of 15 days and the observations obtained are analyzed statistically after the end of the study.
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Bhonsle, Amiya, Shweta Parwe, and Milind Nisargandha. "A Comparative Study to Evaluate the Efficacy of Lekhana Basti and Modified Vachadi Gana Basti in Combination with Navaka Guggulu in Sthaulya (Obesity) -A Study Protocol." Journal of Pharmaceutical Research International, June 2, 2021, 154–61. http://dx.doi.org/10.9734/jpri/2021/v33i30a31626.
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Background: Sthoulya described as Obesity occurs due to the vitiation of Kapha & Vata. The signs and symptoms of Sthoulya can be correlated with Obesity. This has been said in Ayurveda and Sthaulya purusha (Obese person) is considered one of the nindita Purusha. Lekhaniya gana contains the drugs like Triphala, Shatpushpa, Madhu (Honey), Ushaka, Kasis, Tuttha, Shilajit, Saindhava (Salt), Yavakshar, Gomutra (Cow Urine) which are having specially lekhaniya (Scraping) properties, Kapha and Meda (fat) hara property, in sthaulya increased kapha and meda (fat) is seen, the medicine having these lekhaniya property helps to scrap the excess fat from the body so this medicine is helpful to reduce fat. While Modified Vachadi Gana (Group of herbs) contains Devdaru (Cedrus Deodara), Shunthi (Zingiber Officinale), Vacha (Acorus Calamus), Haritaki (Terminalia Chebula), Ativisha (Aconitum Heterophyllum), Nagarmotha (Cyperus Rotundus), Ushaka, Kasis (Ferrous Sulfate), Tuttha (Blue Vitriol), Shilajit (Asphaltum), Saindhava (salt), Yavakshar (Hordeum Vulgare), Modified Vachadi gana having vata and kapha hara property & Lekhaniya (Scraping) property both. So it is used in vata kaphaja vikara like sthaulya so to treat it vata kapha reducing medicine is to use. Modified Vachadi Gana having those above properties apart from that also having lekhaniya property. Hence, it also helps to scrap the excess fat from the body, so this medicine is helpful to reduce fat.
 Aim: To study the effect of Lekhana Basti & Modified Vachadi Gana Basti along with Navak Guguulu in sthoulya (Obesity).
 Objectives: To study the impact of Lekhana Basti on body mass index, body circumference measurements, skinfold thickness, lipid profile, To study the impact of Vachadi gana yoga basti (Modified) on body mass index, body circumference measurements, skinfold thickness & lipid profile, To compare the efficacy of Lekhana Basti and Modified Vachadi Gana basti on body mass Index, body circumference measurements, skinfold thickness & lipid profile.
 Materials and Methods: A total of 35 patients will be selected in each group from the outpatient department of Panchakarma MGACH & RC. Basti will be done in Yog basti pattern. In Group A, Lekhana Basti & In Group B, Modified Vachadi Basti will be used. After Basti Krama 16 Days, Parihara Kala is to be given.
 Conclusion: Based on the result conclusion will be drawn.
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Mahajon, Bidhan, C. Murali Krishna, Saroj Kumar Debnath, et al. "Efficacy and Safety of <i>Ayurveda</i> Compound Formulations in <i>Sthoulya</i> (Obesity) Management: A Multi-centric Clinical Trial." Journal of Natural Remedies, May 5, 2025, 867–85. https://doi.org/10.18311/jnr/2025/44762.
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Background: Ayurveda offers a rich repository of medicinal formulations that have been traditionally used for various health conditions, including obesity. Scientific validation is essential to establish their efficacy and safety in contemporary healthcare. Aim: In this present study, it was aimed to evaluate the clinical efficacy and safety of Navaka Guggulu (NG) with Brihat Manjishtadi Kwatha (BMK) and Tryushnadi Guggulu (TG) with BMK for the treatment of Sthoulya (Obesity). Methods: A prospective, open-label, multi-centric clinical trial was conducted on 240 participants with 20% excess weight than desirable weight, age-adjusted BMI above the 85th percentile, and WHR >0.8 (females) and >0.95 (males). Participants were randomized into two groups: Group I received NG 1 gm twice daily and BMK 50 ml twice daily, while Group II received TG 1 gm twice daily and BMK 50 ml twice daily for 12 weeks. Outcomes were assessed through physical examination, BMI, WHR, EOSS (Edmonton Obesity Scoring System), and laboratory parameters. A paired t-test was used for statistical analysis. Results: Statistical analysis revealed a significant improvement in disease-specific parameters and chief complaints, including polyphagia, polydipsia, and excessive sweating. The mean values of BMI, waist circumference (WC), and WHR were found to be improved in both groups before and after the treatment, as well as during follow-up at the end of the 16th week. Statistical analysis of the EOSS score and laboratory parameters also revealed a significant upshot in both groups. All the interventions were useful in managing the clinical features and biomarkers; also, no clinically significant adverse event was observed. Conclusion: Ayurveda compound formulations NG, TG and BMK are remarkably useful and safe in managing obesity (Sthaulya) in the prescribed dose and comportment. Further, a double-masked, Randomized Controlled Trial (RCT) with an extended follow-up period is recommended to validate these findings. Major Findings: The study showed significant reductions in BMI, waist circumference, and WHR in both intervention groups. Clinical symptoms like polyphagia, polydipsia, and excessive sweating improved notably, with better EOSS scores. No serious adverse effects were reported, indicating the safety and efficacy of the Ayurvedic formulations.
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Singhal, Harish Kumar. "A Clinical Study of the Efficacy of Varadi Kashaya Vati and Navak Guggulu in the Management of Sthaulya w.s.r. to Childhood Obesity." Orthopedics and Rheumatology Open Access Journal 19, no. 5 (2022). http://dx.doi.org/10.19080/oroaj.2022.19.556025.
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