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1

Zhang, Zhong Feng. "Analysis on Pyrolytic Behavior of Wheat Straw Multifunctional Materials by Py-GC-MS." Advanced Materials Research 496 (March 2012): 194–97. http://dx.doi.org/10.4028/www.scientific.net/amr.496.194.

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In order to learn of pyrolytic behavior of wheat straw multifunctional materials, the extractives of wheat straw biomass were adsorbed and determined by Py-GC-MS. And the main constituents were stigmasterol, vitamin e, campesterol, .gamma.-sitosterol, stigmasterol, 22,23- dihydro-, nonacosane, stigmastan-3,5,22-trien, heneicosane, lup-20(29)-en-3-one, 1,2- benzenedicarboxylic acid, buty l 2-methylpropyl ester, stigmast-4-en-3-one, stigmastan-3,5-diene, 4,22-stigmastadiene-3-one, cholest-5-en-3-ol (3.beta.)- , pyridine-3-carboxamide, oxime, etc.
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2

Wachsman, Mónica B., Elsa MF López, Javier A. Ramirez, Lydia R. Galagovsky, and Celia E. Coto. "Antiviral Effect of Brassinosteroids against Herpes Virus and Arenaviruses." Antiviral Chemistry and Chemotherapy 11, no. 1 (2000): 71–77. http://dx.doi.org/10.1177/095632020001100107.

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A natural brassinosteroid and a series of synthetic derivatives were found to be good inhibitors of herpes simplex virus type 1 (HSV-1) and arenavirus replication in cell culture. The synthetic compounds tested were analogues of the 24(S) ethylbrassinone. Compounds (22R,23R,24S)-2α, 3α,5α,22,23-pentahydroxy-stigmastan-6-one and (22R,23R,24S)-3β-bromo-5α,22,23-trihydroxy stigmastan-6-one were cytotoxic at concentrations of 20–40 µM. (22S,23S,24S)-2α,3α,22,23-tetrahydroxy-5α,stigmastan-6-one, (22R,23R,24S)-3β-acetoxy-22,23-dihydroxy-5α-cholestan-6-one, (22S,23S,24S)-3β-bromo-22,23-dihydroxy-5α-c
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3

Wang, Lan Sheng, and Wan Xi Peng. "Py-GC-MS Analysis on Biomass Energy Components from Wood Extractives of Eucalyptus urophydis under High Temperature." Applied Mechanics and Materials 164 (April 2012): 30–32. http://dx.doi.org/10.4028/www.scientific.net/amm.164.30.

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In order to widely use Eucalyptus urophydis wood, its ether/acetone extractives were identified by Py-GC/MS. The main and abundant constituents of 750°С pyrolysis products were 1,3-butadiene, 2-methyl-(5.9%), benzofuran, 2,3-dihydro-(4.11%), 1,3-butadiene(3.69%), stigmastan-3,5-diene (3.66%),.gamma.-sitosterol(2.13%), 2-butene, 2,3-dimethyl-(2.03%), toluene (1.92%), 1,4- cyclohexadiene,1-methyl-(1.76%), 1h-indene, 5-butyl-6-hexyloctahydro-(1.73%), 1,3-cyclohexadiene(1.66%), phenol(1.58%), 1-hexene(1.54%), sulfide, bis(2-cyano-3,4- dihydro- 2,3,3-trimethyl-2h-pyrrol-5-yl)- (1.46%), benzene(1.38
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4

Rufai, Y., N. Basar, and A. Sani. "Optimization and Isolation of 4,8,12,16-Tetramethylheptadecan-4-olide from Deinbollia pinnata." Asian Journal of Chemistry 31, no. 11 (2019): 2503–11. http://dx.doi.org/10.14233/ajchem.2019.22165.

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Manual agitation on ultrasonic assisted extraction process, fractionation, isolation and purification afforded 4,8,12,16-tetramethylheptadecan-4-olide (1) along with 11 compounds 2-12 i.e., squalene (2), phytyl palmitate (3), lupeol (4), taraxasterol (5), myristic acid (6), palmitic acid (7), campesterol (8), stigmasterol (9), λ-sitosterol (10), stigmastan-3, 5-diene (11) and stigmasta-5,22-diene-3-ol acetate (12). Their structures were elucidated spectroscopically (2D NMR, IR, GC-MS and 1D NMR). The optimal conditions for high yield of extracts were obtained at 45 °C, after 35 min and solvent
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5

Bernardo, Yamilé, Esther Alonso, Francisco Coll, Danahe Coll-García, Carlos Pérez та Georgina Agüero. "Synthesis of (22R,23R)-22,23-epoxy-3β,5α-dihydroxystigmastan-6-one from Stigmasterol". Journal of Chemical Research 2005, № 7 (2005): 475–77. http://dx.doi.org/10.3184/030823405774309203.

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6

Chou, Shen-Chieh, Vivek Krishna, and Chang-Hung Chou. "Hydrophobic Metabolites from Rhododendron formosanum and their Allelopathic Activities." Natural Product Communications 4, no. 9 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400906.

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Eighteen components were isolated from the methanolic extract of leaves of Rhododendron formosanum Hemsl. (Ericaceae), an endemic species in Taiwan, and evaluated for their allelopathic properties. Of the isolated compounds, 3 β-friedelinol, 5,6β-epoxy-5β-stigmastan-3β-ol, 5,6α-epoxy-5α-stigmastan-3 β-ol, lupeol and ursolic acid revealed inhibitory effects at 10−4 M or above, whereas α-tocopherol, friedelin and β-amyrin acetate exhibited stimulatory effects on the radicle growth of the test plants at the same concentration or above. However, squalene and α-amyrin showed either a stimulatory or
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7

AVIJIT, BANERJI, NANDI GOPA та BARAN KUNDU AMIT. "Investigation of Croton caudatus Geisellsolation of Stigmastan-3,6-dione, 5α". Journal of Indian Chemical Society Vol. 65, Jun 1988 (1988): 459. https://doi.org/10.5281/zenodo.6303623.

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Chemistry Department, University College of Science, Calcutta -700 009 Regional Research Institute, C.C.R.A.S., Calcutta-700 009 <em>Manuscript received 17 June 1987, </em>revised <em>6 April</em> <em>1988, accepted 12 April 1988</em> Investigation of <em>Croton caudatus</em> Geisellsolation of Stigmastan-3,6-dione, 5&alpha;.
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8

Rachmi Ridho, Bambang Pontjo Priosoeryanto, Esti Mumpuni, Andri Prasetiyo, and Syamsudin Abdillah. "In Silico Studies: Stigmastan-3,6-dione in the Ethyl Acetate Fraction of Momordica charantia L Fruit has immunostimulant and anti-inflammatory activity." Journal of Natural Product for Degenerative Diseases 2, no. 1 (2024): 1–14. http://dx.doi.org/10.58511/jnpdd.v2i1.6865.

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Momordica charantia L fruit provides an immunomodulatory effect by stimulating certain components of the body's immune system. Bioactive phytochemicals from M. charantia L function as anti-inflammatory agents by reducing levels of pro-inflammatory cytokine secretion including IL-1, IL-6, IL-8, TNF-α, NF-kB. This research looks at the insilico mechanism of action of the active ingredient of the EtOAc fraction of M. charantia L fruit as an immunostimulant and anti-inflammatory. The materials and methods used were an Intel Core i7 10 Th Gen laptop, Chem Office Professional 17.1, Chem 2D, Chem 3D
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9

Ma, Qing Zhi, Chao Feng Zeng, Wan Xi Peng, and Xu Zhang. "Analysis on Active Behavior of Bagasse by Py-GC-MS." Advanced Materials Research 230-232 (May 2011): 212–16. http://dx.doi.org/10.4028/www.scientific.net/amr.230-232.212.

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In order to find out its active behavior, the extractives of bagasse biomass were adsorbed and determined by Py-GC-MS. And the main constituents were 1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-di methyl-7- (1-methylethyl)-(52.25%), stigmastan- 3,5-diene (11.3%), 2(1h)-phenanthrenone, 3,4,4a, 9,10,10a-hexahydro-7-hydroxy-1,1,4a-tri methyl-8- (1-methylethyl) - (9.00%), 2- furancarboxaldehyde, 5-(hydroxym ethyl)- (6.25%), etc.
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10

Yang, Ai Mei, Hui Li, Jie Li Liu, Wei Jie Guo, and Rui Wu. "Chemical Constituents of Euphorbia altotibetica." Advanced Materials Research 634-638 (January 2013): 905–8. http://dx.doi.org/10.4028/www.scientific.net/amr.634-638.905.

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Nine compounds were isolated from the petroleum ether extract of Euphorbia altotibetica. The structures of these compounds were elucidated as: squalene (1), β-sitosterol acetate (2), 11, 15, 19, 23-tetramethy-5, 9, 17-tetracosatrienoic acid (3), physcion (4), (z)-10-nonadecenoic acid (5), (z)-4-undecenoic acid (6), β-sitosterol (7), (24S)-stigmastan-4-en-3-one (8), naringenin (9). These compounds were identified on the basis of comparing their NMR datas with those of corresponding compounds in the literature.
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11

Kanwal, Qudsia, Mahmood Ahmed, Atiq Ur-Rehman, et al. "Hypolipidemic Effect of Chloroform Extract of Lagenaria siceraria: Potential Inhibitory Activity of Phytochemicals Targeting the HMG-CoA Reductase Revealed by Molecular Docking and Simulation Studies." Journal of Chemistry 2023 (December 18, 2023): 1–15. http://dx.doi.org/10.1155/2023/3010463.

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Conventional systems of medicine play a crucial role in maintaining healthcare. Herbal medicines are intact and less harmful to human beings than synthetic medicines. This study aimed to investigate the phytochemicals and in vivo hypolipidemic effect of chloroform extract of Lagenaria siceraria in Triton X-100 (100 mg/kg body weight) induced hyperlipidemic Wistar rats. The phytochemical characterization and estimation were performed on the base of the GC-MS approach. The Lagenaria siceraria extract (250 and 500 mg/kg bw) was administered orally to hyperlipidemic-induced rats for 7 days to exam
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12

Qiao, Jian Zheng, Yi Qiang Wu, Chao Feng Zeng, and Wan Xi Peng. "Analysis on Pyrolytic Behavior of Bagasse Multifunctional Materials by Py-GC-MS." Advanced Materials Research 230-232 (May 2011): 298–300. http://dx.doi.org/10.4028/www.scientific.net/amr.230-232.298.

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In order to learn of pyrolytic behavior of bagasse multifunctional materials, the extractives of bagasse biomass were adsorbed and determined by Py-GC-MS. And the main constituents were 1-phenanthrenecarboxylic acid,1,2,3,4,4a,9,10,10a-octahydro-1,4a-di methyl-7-(1-methylethyl)-( 37.99%), decanoic acid, 1,2,3-propanetriyl ester(5.73%), tridecane, 2-methyl-(5.09%), dodecanoic acid, 1-(hydroxymethyl) -1,2-ethanediyl ester(4.52%), stigmastan-3,5-diene(3.81%), glycine, furan-2-yl-methyl ester(3.45%), 1-hexacosene(2.18%), 1-docosene(2.08%), kaura-9(11),16-dien-18-oic acid, (4.alpha.)- (2.07%), etc.
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13

T.P., KUKINA, and ELSHIN I.A. "TERPENE AND ALIPHATIC PRODUCTS OF SAPONIFICATION OF THE ETHER EXTRACT OF EUPHORBIA VIRGATA WALDST. ET KIT." Chemistry for Sustainable Development 32, no. 4 (2024): 485–91. http://dx.doi.org/10.15372/csd2024582.

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The composition of the lipophilic components of Euphorbia virgata Waldst. et Kit. has been studied. Acidic and neutral components have been identified using gas-liquid chromatography with mass spectrometric detection (GC-MS) following alkaline hydrolysis of the whole extract. The plant material was extracted with methyl tert-butyl ether (MTBE). Total acids isolated during sample preparation were analysed after methylation with diazomethane. The composition of the neutral components of unsaponifiable residue was studied without derivatisation, but after separation by column chromatography on si
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14

Wu, Feng Juan, Wan Xi Peng, Zhong Feng Zhang, and Qing Zhi Ma. "Py-GC-MS Analysis on Extractives of Phyllostachys pubescens for Biomedical Engineering." Key Engineering Materials 480-481 (June 2011): 235–37. http://dx.doi.org/10.4028/www.scientific.net/kem.480-481.235.

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In order to evaluate its potential health risk to biomedical engineering, the extractives of Phyllostachys pubescens were adsorbed and determined by Py-GC-MS. And the main constituents were 1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7 -(1-methylethyl)-(23.41%), benzofuran, 2,3-dihydro-(3.2%), cyclobutene(2.77%), 1-nonadecene (2.18%), isopropylcyclobutane(2.16%), stigmastan-3,5-diene(2.14%), benzene(2.03%), 1-hexadecene(1.99%), 1,3-butadiene, 2-methyl-(1.81%), glycerin(1.75%), 1-hexene(1.64%), phenol, 4-methyl-(1.55%), 2-methyl-1-butene(1.54%), toluene(1.47%), 1,
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15

Bernardo, YamilÉ, Esther Alonso, Francisco Coll, Carlos PÉrez та Georgina AgÜero. "Synthesis of (22R,23R)-2α,3α,22,23-diepoxy-5α-hydroxy-stigmastan-6-one from stigmasterol". Journal of Chemical Research 2006, № 3 (2006): 176–78. http://dx.doi.org/10.3184/030823406776330783.

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16

Zhang, Zhong Feng, Xian Yan Zhou, and Qing Zhi Ma. "Study on Biomedical Prospects of Benzene-Alcohol Extractives of Bamboo Leaves." Key Engineering Materials 467-469 (February 2011): 1706–10. http://dx.doi.org/10.4028/www.scientific.net/kem.467-469.1706.

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Bamboo leaves has been used to heal some diseases in the Chinese Folk for a long time. In order to explore the wide biomedicine utilization, the chemical components of benzene-alcohol extractives from the fresh bamboo leaves was studied by Py-GC/MS. The results indicated that the main components were decanoic acid, 1,2,3-propanetriyl ester(5.6%), 9-octadecyne(3.21%), tricosane (2.88%), .gamma.-sitosterol(2.81%), phenylpropionic acid,.alpha.-amin o-2-fluoro-4-hydroxy-5- methoxy-(2.76%), stigmastan-3,5-diene(2.69%), 4h-benzo[f]pyrrolo[1,2-a][1,4]diaz epine, 4-(2-phenyl -propyl)-5,6- dihydro-(2.6
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17

Setianingsih, Sari, Rudi Kartika, and Partomuan Simanjuntak. "Isolasi Senyawa Kimia Stigmastan-3,5-Diena Yang Mempunyai Daya Toksik Dari Daun Ekaliptus (Eucalyptus Deglupta Blume.)." JURNAL KIMIA MULAWARMAN 15, no. 1 (2017): 1. http://dx.doi.org/10.30872/jkm.v15i1.491.

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This study was started by extraction of Eucalyptus deglupta Blume. Using organic solvent (n-hexane, ethyl acetate, ethanol and water) followed by phytochemical screening and toxicity test using Brine Shrimp Lethality Test (BSLT) method. Isolation and identification of chemical compounds contained in the fraction were done by column chromatography and Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Phytochemical screening revealed the presence of alkaloids, flavonoids, steroids and phenolics in the extract. Toxicity test results showed that the ethyl acetate extract was potentially activ
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18

T.P., KUKINA, ELSHIN I.A., SHCHERBAKOV D.N., and SALNIKOVA O.I. "LIPOPHILIC SUBSTANCES OF THE ROOTS AND RHIZOMES OF LEUZEA SAFFLOWER (RHAPONTICUM CARTHAMOIDES (WILLD.) ILJIN)." Chemistry for Sustainable Development 32, no. 4 (2024): 492–99. http://dx.doi.org/10.15372/csd2024583.

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The qualitative composition of lipophilic secondary metabolites in the medicinal plant leuzea safflower (Rhaponticum carthamoides (Willd.) Iljin) has been studied by gas chromatography - mass spectrometry. The roots and rhizomes of this plant species were used as the raw material. Hexane and methyl tert-butyl ether (MTBE) were used as extractants. Two extraction schemes were used (exhaustive and sequential), which allowed us to obtain more detailed information on the composition of components of the raw material. The obtained lipophilic extracts were separated into acid and neutral components
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Odozi, Nnenna Winifred, and Valentine Osi. "Screening, molecular docking and dynamic simulations of bioactive compounds from Prunus africana’s stem bark for potential prostate cancer inhibitors." Acta Chimica Asiana 8, no. 1 (2025): 574–83. https://doi.org/10.29303/aca.v8i1.224.

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Prostate cancer is a major health problem for men, with few effective treatment choices. The growing interest in plant-based medicines needs more research into their safety and efficacy. In this study, twenty-seven (27) phytochemicals found in Prunus africana stem bark are evaluated using in silico methodologies such as toxicological and virtual screening, molecular docking, and molecular dynamics simulations. The PASS server projected that twenty (20) of these chemicals had anticancer properties. Molecular docking studies revealed that four bioactive compounds—β-Sitosterol (-8.9 kcal/mol), Ca
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20

S. Hasanuddin, Erisman, E. Meilanda, et al. "INHIBITORY ACTIVITY, METABOLITE CONTENTS DETERMINATION, AND IN SILICO PREDICTION OF PARSLEY LEAVES FRACTION (Petrocelinum crispum MILL) AS ANTIFUNGAL AGENT OF Malassezia furfur." RASAYAN Journal of Chemistry 15, no. 02 (2022): 1539–46. http://dx.doi.org/10.31788/rjc.2022.1526753.

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Petrocelinum crispum leaves have Furocoumarin as an antimicrobial agent. In this present research, we examine the inhibitory activity of Parsley leaves fractions against Malassezia furfur by disc diffusion paper methods, determine the metabolite contents by LC-MS, and predict the biological activity and toxicity by in silico PASS Prediction. The inhibitory activity of both ethyl acetate and hexane fractions gave medium inhibition at concentrations of 0.15g/ml and 0.3g/ml, respectively. The metabolite contents were revealed by LC-MS, and the PASS prediction showed that the metabolite compounds
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21

Yuliastri, W. O., A. Diantini, M. Ghozali, I. Sahidin, and M. Isrul. "PHYTOCHEMICAL CONSTITUENT AND In-vitro CYTOTOXIC ACTIVITY OF Hibiscus sabdariffa L. CALYX FRACTION ON HUMAN BREAST CANCER CELL LINE MDA-MB-231." RASAYAN Journal of Chemistry 15, no. 03 (2022): 1619–25. http://dx.doi.org/10.31788/rjc.2022.1536694.

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Hibiscus sabdariffa L. is a medicinal plant that has various pharmacological activities. One of the activities of Hibiscus sabdariffa L. is the immunomodulatory activity closely connected with the anticancer activities. This study aimed to test the cytotoxic activity of Hibiscus sabdariffa L. Calyx Fractions against breast cancer cells (MDA-MB-231), determine the active fractions, and analyze the compounds of the active fraction of Hibiscus sabdariffa L. with LCMS. The Hibiscus sabdariffa L.Calyx was fractionated using vacuum liquid chromatography. Meanwhile, the cytotoxic activity was examine
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22

Peng, Wan Xi, Hong Chen Qi, Zhong Feng Zhang, and Lan Sheng Wang. "Py-GC/MS Analysis on Biomedicine of Benzene/Ethanol Extractives from Eucalyptus camaldulensis Biomass." Key Engineering Materials 467-469 (February 2011): 1702–5. http://dx.doi.org/10.4028/www.scientific.net/kem.467-469.1702.

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The benzene/ethanol extractives of Eucalyptus camaldulensis biomass were identified by Py-GC/MS to find out biomedical application. The main 350°С pyrolysis components were 1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)- (21.22%), .beta.-sitosterol acetate (6.4%), stigmasterol, 22,23-dihydro-(5.87%), ergosta-4,6,22-trien-3.beta.-ol(3.6%), etc. The main 350°С pyrolysis components were 1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)- ( 23.58%), ergosta-4,6,22-trien- 3.alpha.-ol(6.27%), decanoic acid, 1,2,3
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Bhumika Reddy Battagiri, Sai, Sai Rushitha Bhimavarapu, Nitya Chalasani, et al. "DOCKING STUDIES FOR EXPLORING THE ANTI-CANCER POTENTIAL OF BIOACTIVE COMPOUNDS." International Journal of Advanced Research 11, no. 10 (2023): 786–90. http://dx.doi.org/10.21474/ijar01/17767.

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Cancer continues to be a leading cause of global morbidity and mortality, necessitating innovative approaches for drug discovery and development. In this study, we employed molecular docking simulations to investigate the potential anti-cancer properties of bioactive compounds against critical oncogenic targets. A diverse set of bioactive compounds, sourced from natural products and synthetic libraries, were selected for their known biological activities and structural diversity.While cancer diagnoses have been documented for a century, the root causes remained elusive to physicians. This stud
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Rechab, S. Odhiambo, G. Kareru Patrick, K. Mwangi Erastus, and W. Onyango Daniel. "Contraceptive and Phytochemical Profile of Lime-Yellow Pea (Macrotyloma axillare, E. Mey) Verdc: A Tropical Climber." European Journal of Medicinal Plants 19, no. 2 (2017): 1–13. https://doi.org/10.9734/EJMP/2017/33957.

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<strong>Background:</strong> Rising human population has detrimental effects on quality of life and lead to increased cases of pollution and poverty. Modern forms of contraceptives also have severe side effects and result in high cases of unwanted pregnancies. As a result, several cases of illegal abortion, leading to serious health complications have been reported, and more than 30 million US dollars are used to treat post-abortion complications in Kenya annually. Herbal contraceptives offer alternatives to health problems, and this study was novel with significant findings, since little info
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Kovganko, N. V., та S. N. Sokolov. "Synthesis of (24R)-3β-chloro-7α-bromo-5-hydroxy-5α-stigmastan-6-one and study of its dehydrohalogenation products". Chemistry of Natural Compounds 35, № 5 (1999): 539–42. http://dx.doi.org/10.1007/bf02323290.

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Hapsari, Yatri, Partomuan Simanjuntak, Wien Kusharyoto, and Sumi Hudiyono. "Chemical Constituent and Antimalarial Activity based on Inhibition of Heme Polymerization from Water Extract of Yellow Root (Arcangelisia flava L. Merr)." Chimica et Natura Acta 7, no. 3 (2019): 102. http://dx.doi.org/10.24198/cna.v7.n3.26264.

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In developing countries, malaria remains a disease that can spread easily and caused death. Malaria is an infectious disease caused by Plasmodium sp involving female anopheles masquitos during its transmission. Arcangelisia flava L. Merr has been investigated earlier that it can inhibited P. falciparum growth. Method of antimalarial activity based on inhibition of heme polymerization can confirm one of the mechanism of antimalarial drugs. The aim of this research to study further antimalarial activity and IC50 based on inhibition of heme polymerization and determine the chemical constituent fr
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27

Yao, Na, and Shuya Wei. "Characterization and identification of traditional Chinese handmade paper via pyrolysis-gas chromatography-mass spectrometry." BioResources 16, no. 2 (2021): 3942–51. http://dx.doi.org/10.15376/biores.16.2.3942-3951.

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The traditional method for the identification of paper from different origins relies on microscopy to observe the fiber morphology, which requires professional experience. In this paper, pyrolysis-gas chromatography-mass spectrometry was utilized to analyze five types of traditional Chinese handmade papers, e.g., ramie paper, bamboo paper, bark fiber paper (mulberry paper and kozo paper), and Langdu paper. The results demonstrated that this method can be used to differentiate the four types of handmade papers. A high phenolic compound content was detected in bamboo paper; macromolecular triter
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Radulovic, Niko, and Nevenka Djordjevic. "Steroids from Poison Hemlock (Conium maculatum L.): A GC-MS analysis." Journal of the Serbian Chemical Society 76, no. 11 (2011): 1471–83. http://dx.doi.org/10.2298/jsc110206128r.

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The steroid content of Conium maculatum L. (Poison Hemlock), Apiaceae, a well-known weed plant species, was studied herein for the first time. This was achieved by detailed GC-MS analyses of twenty two samples (dichloromethane extracts of different plant organs of C. maculatum at three or four different stages of phenological development, collected from three locations). In total, twenty four different steroids were identified. Six steroids had an ergostane nucleus while the other ones possessed a stigmastane carbon framework. The identity of these compounds was determined by spectral means (M
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Jemi, Renhart, Royda Dara Ertini Damanik, and Lies Indrayanti. "Aktivitas Larvasida Ekstrak Daun Tumih (Combretocarpus rotundatus (Miq.) Danser) terhadap Larva Aedes aegypti." Jurnal Ilmu Kehutanan 13, no. 1 (2019): 77. http://dx.doi.org/10.22146/jik.46208.

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Penelitian ini bertujuan untuk mengukur kadar ekstrak daun tumih dan menguji aktivitas larvasidanya terhadap Aedes aegypti. Daun tumih dimaserasi dan difraksinasi dengan pelarut metanol, n-heksana, etil asetat, dan etanol. Aktivitas larvasida ekstrak diuji dengan konsentrasi 0, 5, 10, 25, 50, 75, dan 100 ppm. Hasil penelitian menunjukkan rendemen dari ekstraksi daun tumih pada berbagai larutan adalah sebagai berikut ekstrak metanol sebesar 15%, n-heksana 51%, etil asetat 35% dan etanol 85%. Hasil uji fitokimia menunjukkan bahwa ekstrak metanol daun tumih positif mengandung senyawa alkaloid, fl
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Ahmad, Viqar Uddin, Mumammad Shaiq Ali, and K. Usmanghani. "Bondenolide, a New Diterpenoid from the Seeds of Caesalpinia bonduc." Zeitschrift für Naturforschung B 52, no. 3 (1997): 410–12. http://dx.doi.org/10.1515/znb-1997-0319.

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Abstract A new diterpenoid named as bondenolide (1) was isolated from the ethyl acetate soluble part of the methanolic extract of Caesalpinia bonduc (seeds). In addition to 1, four known triterpenoids: α-amyrin [12-ursen-3β-ol], β-amyrin [12-oleanen-3β-ol], lup-20(29)-en-3β-ol, lup-20(29)-en-3β-yl acetate and two known sterols: β-sitosterol [24(R)-stigmast-5-en-3β-ol] and β-sitosteryl galactoside [3-O-β-D -galactopyranosyl-stigmasta-5-enen] were also isolated from the same source.
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31

Royani, Ahmad, Muhammad Hanafi, Puspa Dewi N. Lotulung, Heddy Julistiono, Achmad Dinoto, and Azwar Manaf. "Analysis of the Antibacterial Activity and the Total Phenolic and Flavonoid Contents of the Moringa oleifera Leaf Extract as an Antimicrobial Agent against Pseudomonas aeruginosa." Scientifica 2023 (September 30, 2023): 1–13. http://dx.doi.org/10.1155/2023/5782063.

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Pseudomonas aeruginosa is a bacterium that causes metal deterioration by forming biofilms on metal surfaces. This work was carried out to analyze the antibacterial activity and the phenolic and flavonoid contents of the Moringa oleifera leaf extract against Pseudomonas aeruginosa. M. oleifera leaves were extracted in a methanol solution at different concentrations. The M. oleifera leaf extract yields were 12.84%, 18.96%, and 19.64% for the 100%, 75%, and 50% methanol ratios, respectively. Extracts of M. oleifera leaves had a minimum inhibiting concentration (MIC) of approximately 6144 μg/mL ag
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Indriani, Indriani, Nanik Siti Aminah, and Ni Nyoman Tri Puspaningsih. "Antiplasmodial Activity of Stigmastane Steroids from Dryobalanops oblongifolia Stem Bark." Open Chemistry 18, no. 1 (2020): 259–64. http://dx.doi.org/10.1515/chem-2020-0027.

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AbstractThree stigmastane steroids: 6-hydroxystigmast-4-en-3-one (1), stigmast-4-en-3-one (2), and 3-hydroxystigmast-5-en-7-one (3) were successfully isolated from the acetone extract of Dryobalanps oblongifolia stem bark. The structural determination of isolated compounds was carried out on the basis of data analysis of NMR and MS spectra. In order to identify the antiplasmodial activity, the isolated compound was put to test against Plasmodium falciparum 3D7. Antiplasmodial activity of the isolated compounds showed that the IC50 values of 6-hydroxystigmast-4-en-3-one were 37.29 μg/mL while t
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Muhit, Md Abdul, Kaoru Umehara, Nahid Sharmin, and Hiroshi Noguchi. "Cycloartane and Stigmastane Type Triterpenoids from Pothos scandens Inhibit Estradiol (E2) Induced Proliferations in Breast Cancer Cells." Dhaka University Journal of Pharmaceutical Sciences 18, no. 1 (2019): 93–102. http://dx.doi.org/10.3329/dujps.v18i1.41896.

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Four cycloartane type triterpenoids and three stigmastane type steroids were isolated from the methanolic extract of stem and root part of Pothos scandens L. (Araceae), a Bangladeshi medicinal plant by high performance liquid chromatographic technique. The compounds were characterized as 24-methylenecycloartanol (1), 24-methylenecycloartenone (2), 24-en-cycloartenone (3), 24-methylenecycloartanyl ferulate (4), stigmast-4-en-3-one (5), stigmast-4,22-diene-3-one (6) and β-sitosterol glucoside (7) through extensive 1D and 2D NMR spectroscopic studies. All the isolates were evaluated for their est
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Hadanu, Ruslin, Irwansyah, Sartika G. P., and Retno Wahyuningrum. "Compound Characterization and Evaluation of Antioxidant Potential of Ethanol Extract Spatholobus littoralis Hassk in Kolaka, Southeast Sulawesi, Indonesia." Journal of Pharmaceutical Research International 35, no. 28 (2023): 59–70. http://dx.doi.org/10.9734/jpri/2023/v35i287450.

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The bajakah tampala plant (Spahtolobus littoralis Hassk) has been traditionally believed by the public to cure cancer, tumors, heart disease, stroke, and diabetes. However, empirically the public does not yet know the chemical compound content and there have been no studies on biological activity tests, especially the antioxidants of bajakah tampala from Kolaka, Southeast Sulawesi. The aim of this research is a qualitative analysis of the chemical compounds of the ethanol extract of bajakah tampala roots and testing of antioxidant activity. Analysis of the chemical compounds of the ethanol ext
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Chen, Chien-Kuang, Shiou-Ling Tuh, Chung-Hsiung Chen, Chen-Meng Kuo, and Shoei-Sheng Lee. "Triterpenoids and Sterols from the Stem of Alnus Formosana Burk." Natural Product Communications 1, no. 4 (2006): 1934578X0600100. http://dx.doi.org/10.1177/1934578x0600100406.

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The chemical constituents of the stem of Alnus formosana Burk. were investigated and sixteen known compounds, composed of eleven triterpenoids and five sterols, were isolated and characterized from the n-hexane- and chloroform-soluble fractions of the methanol extract. Of these, seven triterpenoids, lupeol, lupenone, betulinic acid, 3-O-acetylbetulinic acid, 3-O-acetylerythrodiol, 3-O-acetyloleanolic aldehyde, and taraxerone, were isolated for the first time from an Alnus species. The isolation of the five sterols, stigmastanone, stigmast-4-en-3-one, β-sitosterol, β-sitosteryl-β-D-glucoside, a
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Asaraja, A., and K. Sahayaraj. "SCREENING OF INSECTICIDAL ACTIVITY OF BROWN MACROALGAL EXTRACTS AGAINST DYSDERCUS CINGULATUS (FAB.) (HEMIPTERA: PYRRHOCORIDAE)." Journal of Biopesticides 06, no. 02 (2013): 193–203. http://dx.doi.org/10.57182/jbiopestic.6.2.193-203.

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ABSTRACT The marine algae, popularly known as seaweeds are one of the most important marine resources of the world. The biocidal activity of hexane (HE), chloroform (CH), methanol (ME) and water (WA) extracts (100, 200, 400, 600 and 800 ppm) of brown algae (Ochrophyta), Sargassum wightii (Greville ex J. Agardh) (SW) and Padina pavonica (Linn.) Thivy (PP) was assessed against Dysdercus cingulatus (Fab.). GC-MS results revealed that S. wightii showed the presence of stigmastan-6, 22-dien, 3, 5-dedihydro- (71.34%) whereas P. pavonica showed hexadecanoic acid, methyl ester (43.26%). The chloroform
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Enadeghe, Rosephine, Samuel I. Ojeaburu, and Olusanya Olasehinde. "FUNCTIONAL AND NUTRITIONAL COMPOSITION OF ACTIVATED CHARCOAL OF Terminalia Catappa." FUDMA JOURNAL OF SCIENCES 8, no. 3 (2024): 82–88. https://doi.org/10.33003/fjs-2024-0803-2537.

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Terminalia catappa (T. catappa) is a folklore plant whose leaves, roots and stem bark treat various infectious diseases such as dermatosis and hepatitis. However, herbalists often transform some parts, like the stem, via pyrolysis to charcoal to achieve a different therapeutic outcome. Charcoal has been known as an anti-poisonous substance with no therapeutic or nutritional relevance. This study transformed the stem bark of T. catappa to charcoal, evaluated its proximate minerals and phytochemical compounds using standard methods, including inductive coupled plasma atomic emission spectroscopy
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Shaari, Khozirah, Seema Zareen, Muhammad Nadeem Akhtar, and Nordin Hj Lajis. "Chemical Constituents of Melicope ptelefolia." Natural Product Communications 6, no. 3 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600308.

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Phytochemical investigations on the methanolic extract of Melicope ptelefolia Champ ex Benth. resulted in the isolation of three new compounds, identified as 3β-stigmast-5-en-3-ol butyl tridecanedioate (melicoester) (1), (2 Z,6 Z,10 Z,14 Z,18 Z,22 Z,26 E)-3′,7′,11′,15′,19′,23′,27′,31′-octamethyldotriaconta-2,6,10,14,18,22,26,30-octadecanoate (melicopeprenoate) (2) and p- O-geranyl-7″-acetoxy coumaric acid (3). The compounds were isolated along with twenty-one other known compounds, lupeol (4), oleanolic acid (5), kokusaginine (6) genistein (7), p-O-geranyl coumaric acid (8), 4-stigmasten-3-one
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39

Krzaczek, Tadeusz, and Monika Gawrońska-Grzywacz. "Sterol composition from inflorescences of Hieracium pilosella L." Acta Societatis Botanicorum Poloniae 75, no. 1 (2011): 29–32. http://dx.doi.org/10.5586/asbp.2006.005.

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The fraction of sterol acetates from the inflorescences of &lt;em&gt;Hieracium pilosella&lt;/em&gt; has been isolated in the typical way from petroleum ether extract. By means of the weight method the total amount of sterols was determined (0.2659%). The mixtures of sterol acetates and free sterols were investigated using GC-MS techniques. The occurrence of about 18 sterols has been observed. Cholesterol, cholest-8(14)-en-3b-ol, cholesta-5.7-dien-3b-ol, cholest-7-en-3b-ol, ergosta-5.24-dien-3b-ol, campesterol, stigmasterol, b-sitosterol, fucosterol, 5a-stigmast-7-en-3a-ol were identified. The
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Khan, Iqra Haider, and Arshad Javaid. "Antifungal activity and GC-MS analysis of n-butanol extract of quinoa (Chenopodium quinoa Willd.) leaves." Bangladesh Journal of Botany 49, no. 4 (2020): 1045–51. http://dx.doi.org/10.3329/bjb.v49i4.52537.

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Dry leaves of quinoa (Chenopodium quinoa Willd.) were extracted in methanol and its n-butanol fraction was separated. Solvent was evaporated and antifungal bioassays were carried out against Macrophomina phaseolina using different concentrations (1.562, 3.125, 6.25, 12.50, 25, 50, 100, 200 mg/ml) of the extract in malt extract broth. The entire set of concentrations significantly controlled the fungal growth. The lowermost concentration of the extract (1.562 mg/ml) reduced M. phaseolina biomass by 62% over control while all other concentrations completely controlled fungal growth. GC-MS analys
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41

КУКИНА, Т. П., И. А. ЕЛШИН, Д. Н. ЩЕРБАКОВ, and О. И. САЛЬНИКОВА. "Lipophilic Substances of the Roots and Rhizomes of Leuzea Safflower (Rhaponticum carthamoides (Willd.) Iljin)." Химия в интересах устойчивого развития 32, no. 4 (2024): 509–16. http://dx.doi.org/10.15372/khur2024583.

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Методом хромато-масс-спектрометрии изучен качественный состав липофильных вторичных метаболитов лекарственного растения левзеи сафроловидной (Rhaponticum carthamoides (Willd.) Iljin). В качестве сырья использованы корни и корневища растения. В качестве экстрагентов – гексан и метил-трет-бутиловый эфир (МТБЭ). Применены две схемы экстракции (исчерпывающая и последовательная), что позволило получить более подробную информацию о составе компонентов исследуемого сырья. Для анализа полученные липофильные экстракты разделяли на кислые и нейтральные компоненты путем обработки растворами NaOH и KOH. К
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42

Takatsuto, Suguru, Kiyomi Kobayashi, Tsuyoshi Watanabe, Hiroki Kuriyama та Tokuo Furuse. "(22E,24S)-5α-stigmasta-3,22-dien-6-one: An Intermediate of the Isomerization of (22E,24S)-3α,5-Cyclo-5α-stigmast-22-en-6-one into (22E,24S)-5α-Stigmasta-2,22-dien-6-one". Agricultural and Biological Chemistry 52, № 12 (1988): 3217–18. http://dx.doi.org/10.1080/00021369.1988.10869217.

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43

Habiger, R. G. K., J. M. Cassal, H. J. M. Kempen, and J. Seelig. "Influence of stigmastanol and stigmastanyl-phosphorylcholine, two plasma cholesterol lowering substances, on synthetic phospholipid membranes. A 2H- and 31P-NMR study." Biochimica et Biophysica Acta (BBA) - Biomembranes 1103, no. 1 (1992): 69–76. http://dx.doi.org/10.1016/0005-2736(92)90058-t.

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44

Tabassum, Sobia, Saeed Ahmad, Kashif ur Rehman Khan, et al. "Phytochemical Profiling, Antioxidant, Anti-Inflammatory, Thrombolytic, Hemolytic Activity In Vitro and In Silico Potential of Portulacaria afra." Molecules 27, no. 8 (2022): 2377. http://dx.doi.org/10.3390/molecules27082377.

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The use of complementary herbal medicines has recently increased in an attempt to find effective alternative therapies that reduce the adverse effects of chemical drugs. Portulacaria afra is a rich source of phytochemicals with high antioxidant activity, and thus may possess health benefits. This study used the latest developments in GC-MS coupling with molecular docking techniques to identify and quantify the phytoconstituents in P. afra tissue extracts. The results revealed that n-butanol P. afra (BUT-PA) dry extracts contained total phenolic and flavonoids contents of 21.69 ± 0.28 mgGAE/g a
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45

Akbay, Pınar, Ihsan Çalıs, Jörg Heilmann, and Otto Sticher. "New Stigmastane Sterols fromAjuga salicifolia." Journal of Natural Products 66, no. 4 (2003): 461–65. http://dx.doi.org/10.1021/np020427e.

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46

Watanabe, Tsuyoshi, Hiroki Kuriyama, Tokuo Furuse, Kiyomi Kobayashi та Suguru Takatsuto. "An Efficient Preparation of (22E,24S)-5α-Stigmasta-2,22-dien-6-one from (22E,24S)-3α,5-Cyclo-5α-stigmast-22-en-6-one". Agricultural and Biological Chemistry 52, № 8 (1988): 2117–18. http://dx.doi.org/10.1080/00021369.1988.10868959.

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47

Tan, Dai Chuan, Nur Kartinee Kassim, Intan Safinar Ismail, Muhajir Hamid, and Muhammad Safwan Ahamad Bustamam. "Identification of Antidiabetic Metabolites from Paederia foetida L. Twigs by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Study." BioMed Research International 2019 (May 29, 2019): 1–14. http://dx.doi.org/10.1155/2019/7603125.

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Paederia foetida L. (Rubiaceae) is a climber which is widely distributed in Asian countries including Malaysia. The plant is traditionally used to treat various diseases including diabetes. This study is to evaluate the enzymatic inhibition activity of Paederia foetida twigs extracts and to identify the metabolites responsible for the bioactivity by gas chromatography-mass spectrometry (GC-MS) metabolomics profiling. Three different twig extracts, namely, hexane (PFH), chloroform (PFC), and methanol (PFM), were submerged for their α-amylase and α-glucosidase inhibition potential in 5 replicate
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48

TAKATSUTO, Suguru, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, and Tokuo FURUSE. "(22E, 24S)-5.ALPHA.-stigmasta-3,22-dien-6-one: An intermediate of the isomerizatiion of (22E, 24S)-3.ALPHA.,5-cyclo-5.ALPHA.-stigmast-22-en-6-one into (22E, 24S)-5.ALPHA.-stigmasta-2,22-dien-6-one." Agricultural and Biological Chemistry 52, no. 12 (1988): 3217–18. http://dx.doi.org/10.1271/bbb1961.52.3217.

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WATANABE, Tsuyoshi, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, and Suguru TAKATSUTO. "An efficient preparation of (22E, 24S)-5.ALPHA.-stigmasta-2,22-dien-6-one from (22E, 24S)-3.ALPHA.,5-cyclo-5.ALPHA.-stigmast-22-en-6-one." Agricultural and Biological Chemistry 52, no. 8 (1988): 2117–18. http://dx.doi.org/10.1271/bbb1961.52.2117.

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50

M, Resende, C., Barreto A. S, Pinto, P. R., et al. "TERPENOIDS AND PHYTOSTEROLS ISOLATED FROM PLUMERIA RUBRA L., FORM ACUTIFOLIA (AIT) WOODSON AND ITS FUNGUS PARASITE COLESPORIUM PLUMERIAE." Asian Journal of Pharmaceutical Research and Development 6, no. 6 (2018): 15–22. http://dx.doi.org/10.22270/ajprd.v6i6.428.

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The hexane and ethyl acetate extracts of the leaves from Plumeria rubra L., form acutifolia (Ait) Woodson and the methanolic extract from the fungus Coleosporium plumeriae Pat. were analized by high resolution gas chromatography (HRGC) and by high resolution gas chromatography coupled to mass spectrometes (GC-MS). The identification of the chemical constituintes is these extracts has been made by the automatic comparison of the mass spectra obtained standards within the NBS, Wiley and Wiley 275T librarys supplied with the mass spectrometer and by analized of the principal fragmentations. Phyto
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