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Dissertations / Theses on the topic 'Stilbenoidy'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Holst, Hans Christof. "Stilbenoide Sternsysteme Synthese und Eigenschaften /." [S.l. : s.n.], 2003. http://ArchiMeD.uni-mainz.de/pub/2003/0031/diss.pdf.

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2

Soomro, Shahid A. "Design, synthesis and photochemical studies of stilbenoid dendrimers." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=975958569.

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3

Moss, Ryan Kurtis. "Development and validation of methods for the investigation of wine stilbenoids." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50808.

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Stilbenoids are secondary plant metabolites responsible for the protection of grape vine from bacterial and fungal infection. Red wine has been shown to be a major source of these compounds in the human diet, where they display an array of health benefits. The first goal of our study was to develop and validate a robust and selective method for quantification of the major stilbenoids in red and white wine using ultra-high-performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight mass spectrometry (UHPLC-ESI-Q-TOF)

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4

Ressler, Daniel. "Synthesis of Resveratrol Ester Derivatives." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/1234.

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The goal of this research project was to synthesize derivatives of transresveratrol. In order for resveratrol to be activated and used by the body it needs to bind to Human Serum Albumin (HSA), a protein in blood plasma. The derivatives were synthesized to improve the ability of resveratrol to enter cells as well as improve their ability to bind to HSA. The three derivatives that were synthesized have converted one of the hydroxyl groups on resveratrol to an ether with a methylene chain terminated by a carboxylic acid. By varying the lengths of the methylene chain we varied the water solubilit

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5

Karpouk, Elena. "Photochemie von ungesättigten Sternverbindungen Wirt-Gast-Systeme bei stilbenoiden Dendrimeren /." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971998450.

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6

Van, Cleve Shelley Marie. "Synthesis of a Resveratrol Glycinate Derivative." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1312.

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Recently, the compound resveratrol has had media attention as an anti carcinogen. However, the bioavailability of resveratrol is low in the human system due to its hydrophobic nature. Therefore, it must be administered in high dosages to be effective. A plethora of derivatives have been synthesized that have the potential of resveratrol but sadly share low bioavailability. The first effort of this research was an attempt to produce a more hydrophilic ester of resveratrol. Failing this, the final product was synthesized using a glycine derivative to produce 4-[(1E)-2-(3,5-diacetyloxyphenyl)ethe

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7

Jing, Stanley Mofor. "Synthesis of Resveratrol Esters and Aliphatic Acids." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1382.

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Resveratrol (RV) is a naturally occurring phytoalexin of the stilbenoid family produced by some plant species, and present in grape skin, peanuts, and red wine. It has been found to exhibit anti-cancer, anti-inflammatory, anti-viral, anti-aging, cardio protective, and anti-oxidant properties. Bioavailability is a huge setback that limits the potentials of RV. As a result, efforts have been made to design and synthesize RV esters and aliphatic acids in an attempt to increase its bioavailability, solubility in water, and possibly improving its biological activities. Resveratrol esters, 3,5,4'-tr

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8

Bisson, Jonathan. "Développements méthodologiques en chromatographie de partage : application aux stilbénoïdes." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR22006/document.

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Les stilbénoïdes, sont des composés phénoliques majoritairement issus du règne végétal. La Vigne par l’intermédiaire du vin et du raisin est la principale source alimentaire de stilbènes. La mise en évidence de leur rôle dans les mécanismes de défense des plantes et leurs activités biologiques, y compris sur l’Homme, en font un sujet d’étude en plein essor. L’un des objectifs de cette thèse a été de développer un ensemble de stratégies à la fois analytiques et préparatives utilisant la Chromatographie de Partage Centrifuge (CPC) pour l’étude et l’obtention de ces molécules. Dans un premier tem

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9

Lambert, Carole. "Étude du rôle des stilbènes dans les défenses de la vigne contre les maladies du bois." Thesis, Bordeaux 2, 2011. http://www.theses.fr/2011BOR21910/document.

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Les maladies du bois de la vigne, par exemple le syndrome de l’esca et l’eutypiose, sont dues à des champignons qui se développent dans le xylème et dégradent les tissus ligneux. Elles sont en recrudescence depuis une vingtaine d’année dans tous les vignobles du monde. A ce jour, aucun traitement curatif n’est disponible alors que ces maladies engendrent généralement la mort de la plante. L’étude des relations hôte-parasite et notamment celle des réponses de défense de plante, est nécessaire pour la compréhension et le développement de nouvelles stratégies de lutte. Parmi les molécules de défe

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10

Gali, Meghanath. "Synthesis of Small Molecule Inhibitors of Janus Kinase 2, Phosphodiesterase IV, GABAA and NMDA receptors: Investigation of Mcmurry, Mannich and Chemoenzymatic Strategies." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3110.

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Stilbenoids possess a wide range of biological properties such as, anticancer, antiplatelet aggregation, antiestrogenic, antibacterial, antifungal and antiatherogenic, etc. Owing to these therapeutic values, a great deal of attention attracted in the synthesis of derivatives of stilbenes. During the course of the study, G6 a novel stilbenoid was discovered, through high throughput screening, to be a potent inhibitor of mutated JAK2-V617F. The mutated JAK2 variant has been implicated in various myeloproliferative disorders (MPDs) including polycythemia vera (PV), essential thrombocythemia (ET)

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11

Bayach, Imene. "Non-covalent interactions in natural products." Thesis, Limoges, 2014. http://www.theses.fr/2014LIMO0050/document.

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Les polyphénols naturels forment des complexes non-covalents dans lesquels le π-stacking et les liaisons hydrogène jouent un rôle clé dans la stabilisation. Les calculs DFT incluant la dispersion (DFT-D), la description des processus d'agrégation non-covalente de produits naturels devient fiable. Dans ce travail, les méthodes DFT-D sont appliquées à i) la compréhension de la biosynthèse stéréo- et régio-sélective des oligostilbenoïdes, ii) la prédiction de l'agrégation des antioxydants naturels au sein de la membrane bicouche lipidique, qui pourrait rationaliser la synergie de la vitamine E, l

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12

Houillé, Benjamin. "Valorisation de coproduits de la viticulture, les sarments de vigne, comme source de polyphénols à activité fongicide." Thesis, Tours, 2015. http://www.theses.fr/2015TOUR3807.

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Ce travail porte sur la valorisation de sarments de vigne comme source de polyphénols bioactifs. Après purification d’oligomères du resvératrol et hémi synthèse d’analogues du resvératrol, l’activité antifongique de ces molécules a été testée. Le 3,5-diméthoxyresvératrol a montré des activités intéressantes sur douze espèces du genre Candida. Pendant le stockage des sarments, une forte augmentation en E-resvératrol et E-picéatannol a lieu de façon thermo dépendante et l’expression des gènes PAL, C4H et STS participent à la biosynthèse de novo du E-resvératrol. Une infection par le mildiou au v

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13

Olusegun-Osoba, Elizabeth Oluwakemi. "Strategies towards the synthesis of 4-(3-methyl-but-1-enyl)-3,5,3',4'-tetrahydroxystilbene (arachidin-1) and resveratrol analogues." Thesis, University of Hertfordshire, 2015. http://hdl.handle.net/2299/17118.

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Stilbene phytoalexins such as resveratrol, 1, and the arachidins, including arachidin-1,2, are naturally synthesised by peanut (Arachis hypogaea) plants. The peanut phytoalexins are polyphenolic compounds consisting of a stilbene backbone, with a number of derivatives also possessing a prenyl moiety. These distinctive phytoalexins have gained attention, as they exhibit various biological activities, for instance arachidin-1, 2, has been reported to be more potent than resveratrol, 1, in the inhibition of lipopolysaccharide-induced expression of cyclooxygenase-2 (COX-2) and COX-2 mRNA, in vitro

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14

Auberon, Florence. "Stilbénoïdes et dérivés glucosyloxybenzyliques d’acides organiques isolés d’orchidées tropicales : études chimiques et biologiques de Cyrtopodium paniculatum (Ruiz & Pav.) Garay et Arundina graminifolia (D.Don) Hochr." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAF045.

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Nous avons porté une attention particulière à 2 marqueurs chimiotaxonomiques de la famille botanique des orchidées, les stilbénoïdes et dérivés glucosyloxybenzyliques d’acides organiques, et les avons recherchés dans deux espèces tropicales. L’investigation phytochimique de Cyrtopodium paniculatum (Ruiz & Pav.) Garay a permis l’isolement de 35 stilbénoïdes dont 12 nouvellement décrits. L’évaluation de leur activité cytotoxique in vitro sur la lignée cellulaire cancéreuse UG-87 montre que seuls les stilbénoïdes dimères semblent aptes à induire une perturbation de l’intégrité cellulaire. Nou

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15

Čáková, Veronika. "Contribution à l'étude phytochimique d'orchidées tropicales : identification des constituants d'Aerides rosea et d'Acampe rigida : techniques analytiques et préparatives appliquées à Vanda coerulea et Vanda teres." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-00997451.

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L'analyse de la composition chimique de deux orchidées de la sous-tribu des Aeridinae, Aerides rosea Lodd. ex. Lindl. & Paxton et Acampe rigida (Buch.-Ham. ex Sm.) P. F. Hunt, a été menée en ayant recours à des techniques de couplages et grâce à une stratégie de déréplication. Dix dérivés phénanthréniques ont ainsi été identifiés dans les tiges d'A. rosea, dont deux nouvellement décrits. Quatre stilbénoïdes, trois dérivés d'acides phénoliques et quatre esters d'acide cinnamique ont été identifiés dans les tiges d'A. rigida. Nous avons également effectué des dosages de traceurs dans différents

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16

Linhartová, Lenka. "Molekulární podstata lékových interakcí -interace konstitutivního androstanového receptoru s vybranými stilbenoidy." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-397858.

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Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Lenka Linhartová Supervisor: Prof. PharmDr. Petr Pávek, Ph.D. Title of diploma thesis: Molecular mechanisms of intractions - interactions of constitutive androstane receptor with selected stilbene compounds Constitutive androstane receptor (CAR), member of nuclear receptors family, is a major regulator of gene expression of phase I and II enzymes metabolizing endobiotics and xenobiotics. Changes in its activity can lead to pharmacokinetic drug interactions, ineffective treatment or higher

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17

Bangani, Vuyisile. "Homoisoflavonids and stilbenoids from Scilla species." Thesis, 1998. http://hdl.handle.net/10413/3648.

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Bulbs of Scilla natalensis Planch, Scilla nervosa (Burch.) Jessop, Scilla dracomontana Hilliard and Burt and Scilla kraussii Bak. (Hyacinthaceae) were investigated. The plants are widely used by the local African people for a variety of ailments that inflict them and their livestock. Plant material was harvested in different localities i.e. KwaZulu-Natal (KZN) and Mpumalanga (Mpl). The bulbs have been found to contain homoisoflavonoids and stilbenoids. Ten homoisoflavonoids and two stilbenoids were isolated. Of the ten homoisoflavonoids isolated, nine were of the 3-benzyl-4-chromanone type whi

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18

Holst, Hans Christof [Verfasser]. "Stilbenoide Sternsysteme : Synthese und Eigenschaften / Hans Christof Holst." 2003. http://d-nb.info/967586402/34.

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19

MAŠKOVÁ, Hana. "Antivirotické účinky stilbenoidů proti klíšťaty přenášeným patogenům in vivo." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-376087.

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This study was focused on antiviral effects of stilbenoids against a virus transmitted by ticks. The cell viability of selected cell line cultures in the presence of various concentrations of stilbenoids was determined using the MTT assay. Similarly, the mixed effect of other known antiviral substances and stilbenoids was studied using the MTT assay. Both the prophylactic effects of stilbenoids on the infected culture cell lines and the effect on viral replication were examined. The viral titres from samples were determined using plaque assay. Some of the experiments were performed also in viv

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20

Paul, Shiby. "Inhibition of colon carcinogenesis by stilbenoids and mechanisms of action." 2010. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000052141.

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21

Chung, Ping-Chen, and 鍾秉真. "The effects of peanut stilbenoids on HL-60 cell line." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/78438899024656727438.

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碩士<br>國立臺灣大學<br>醫學檢驗暨生物技術學研究所<br>96<br>Stilbenoids are phytoalexins produced by plants under attack by pathogens such as fungi. Previous sutdies have demonstrated that stilbenoids have bioactivities such as anti-oxidation, anti-inflammation, cancer chemoprevention and anti-carcinogenic effect. In this study, resveratrol (RSV), arachidin-1 (Ara-1), arachidin-3 (Ara-3), and isopentadienylresveratrol (IPD) were isolated from peanuts. RSV, Ara-1 and Ara-3 display cytotoxic effect on HL-60, and Ara-1 is the most toxic. Further study showed that Ara-1 treatment on HL-60 cells caused loss of mitochon

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22

Soomro, Shahid A. [Verfasser]. "Design, synthesis and photochemical studies of stilbenoid dendrimers / Shahid A. Soomro." 2005. http://d-nb.info/975958569/34.

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23

CHU, MEI-YI, and 朱美嬑. "The Anti-Oxidant Mechanism Of Resveratrol And Stilbenoid On Human Keratinocyte." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/7j2h5p.

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碩士<br>長庚科技大學<br>健康產業科技研究所<br>107<br>In many literatures, resveratrol (Res) and stilbenoid have many effects (eg, as anticancer agents, platelet anticoagulants, anti-inflammatory, anti-allergic, etc.), which may be due to their molecular structure, and these structures are capable of binding to many biomolecules. Ampelopsin C 、Ampelopsin F、Polydatin they are all Res and stilbenoid. But their antioxidant effect on the skin is still unknown.In this study, we wanted to investigate whether Res and its derivatives have antioxidant capacity in skin cells, and further explore its mechanism. First,

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24

Jui-Shien, Hsu, and 徐睿仙. "Biosynthesis of the Secondary Metabolites of Stilbenoids by Cotyledon-removed Peanut Embryos." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/7fymp8.

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碩士<br>國立嘉義大學<br>食品科學系研究所<br>107<br>During germination of peanut seeds, stilbene compounds can be detected in the embryos including germs, hypocotyls and roots. In this study, with an attempt to understand mechanism for whether the detected stilbenoids are biosynthesized in the cotyledons and transported to other embryo parts, cotyledons were removed from the 4-day germinated peanut sprouts. The cotyledon-removed embryos were subjected to various physical damages including knife or scissor cutting and machine slicing for 1 cycle and incubation under ambient temperature for 3 days. During incuba

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25

Lin, Li-Lian, and 林麗蓮. "Investigation of stilbenoids in Arachis hypogaea, Polygonum cuspidatum, Ampelopsis brevipedunculaata, and Vitis thunbergii." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/13205493047722851454.

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碩士<br>國立嘉義大學<br>農學研究所<br>94<br>trans-Piceatannol and trans-resveratrol have been proved to have a close relation with antioxidative, anti-inflammatory, and anti-carcinogenesis effects in the tested animal models. In the first part of this study, the traditional Taiwanase herbs including Polygonum cuspidatum, Ampelopsis brevipedunculaata and Vitis thunbergii were used as the samples to evaluate a simple chromatography method with simultaneous extraction and quantitatively analytical approaches. The mobile phase for the reversed-phase chromatography composed of H2O+FA/ACN. Analysis of the sample

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26

鄭雅今. "Induction, analysis and identification of stilbenoids in callus of peanut(arachis hypogaea L.)." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/19887981506432094318.

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碩士<br>國立嘉義大學<br>農學研究所<br>91<br>Abstract It is known that the seeds and roots of peanut possess substantially amount of resveratrol, a phytoalexin compound in some plants. This interests us to find wether the tissue-cultured callus of peanut also contain resveratrol and other stilbenoids. In case it contains stilbenoids, we also would like to know how to produce high stilbenoids callus, which in turn is used as a new resource for resveratrol. Therefore, the main goal of this study is to generate stilbenoids contained peanut callus. To achieve the purpose, there are three i

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27

Schulz, Andrea [Verfasser]. "Synthese und Photochemie von Dendrimeren mit stilbenoiden Chromophoren / Andrea Schulz." 2006. http://d-nb.info/979908485/34.

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28

Karpouk, Elena [Verfasser]. "Photochemie von ungesättigten Sternverbindungen : Wirt-Gast-Systeme bei stilbenoiden Dendrimeren / Elena Karpouk." 2004. http://d-nb.info/971998450/34.

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29

Luo, Chiau-Wen, та 羅喬文. "Inhibition of aggregated Aβ-induced PC-12 cells apoptosis by edible plant material extracts and stilbenoids". Thesis, 2008. http://ndltd.ncl.edu.tw/handle/99483059663155123193.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>96<br>Alzheimer''s disease (AD), the major cause of dementia, is a neurodegenerative disorder associated with impairment in memory and cognitive function. AD is characterized pathologically by the presence of senile plaques (amyloid plaques), and neurofibrillary tangles (NFT). β-amyloid peptide (Aβ) has been proposed to play an important role in the pathogenesis of AD. Deposits of Aβ are found in the brains of patients with AD and are one of the pathological hallmarks of the disease. Many studies have shown that aggregated Aβ can induce caspase-dependent apoptosis an

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Juan, Yi-Chen, and 阮怡禎. "The action mechanisms of stilbenoid derivative ugonstilbene A extracted from Helminthostachys zeylanica (L) Hook in rabbit platelets." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/39737331761831244240.

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碩士<br>國立陽明大學<br>藥理學研究所<br>92<br>Helminthostachys zeylanica, a terrestrial fern of the Ophioglossaceae family, also known as Daodi-Ugonn in Taiwan and Tukod-langit in Malay language. The dry rhizomes were traditionally used to remove blood stasis and promote blood circulation. The folkloric therapies in Southeastern Asia also use them to treat cough in tuberculosis, asthma and poisonous snakebites patients. Stilbenoid can be extracted form various plants and previous studies have revealed its bioactivities in lipid peroxidation inhibition, cyclooxygenase inhibition, calcium channel blocking and

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31

Yu-HsuanShih and 史育璇. "Antibacterial effects and the mechanisms of stilbenoid compounds alone or combined with silver nanoparticles against foodborne pathogens." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/p5j4c4.

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32

Chang, Yong-Ling, and 張永霖. "Studies of Stilbenoid Stability of Peanut Sprout Products and Used as an Ingredient for Processing of Functional Foods." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/x9v796.

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碩士<br>國立嘉義大學<br>食品科學系研究所<br>106<br>Peanut is an important economical crop worldwide with diverse product patterns for consumption. Peanut seeds contain high quality proteins, along with other healthy micronutrients. After processing and rendering the unique peanutty aroma, the processed peanut contained foods are one of the world's most popular consuming products. In recent years, peanut polyphenols have received increasing attention, in particular stilbenoids comprising resveratrol (Res). Many studies have shown that these stilbenoids are potent antioxidants, bearing anti-inflammatory, activ

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Deng, Jie-Ren, and 鄧傑仁. "Antioxidative and antibacterial activities of stilbenoids extracts from peanuts and their effects on quality of sausage products during storage." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/55357594615397049605.

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碩士<br>國立嘉義大學<br>食品科學系研究所<br>98<br>Stilbenoids in peanut kernel have potent bio-activities, such as resveratrol, piceatannol, archidin-1, archidin-2, archidin-3, etc. Some studies indicated that stilbenoids have anti-inflammation, inhibition of tumor growth and prevention of thrombosis. In this study, to evaluate applicability and potential product development of stilbenoids, the stilbenoids were extracted from after sliced hurt peanut kernels by 60 % ethanol. First parts of study to assessed antioxidant properties by DPPH free radical scavenging activity, reducing power and trolox equivalent a

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34

Hsieh, Wan-Yu, and 謝琬喻. "Anti-oxidative and anti-aging effects of several extracts of flowers and fruits as well as stilbenoids in Caenorhabditis elegans model." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/84840001044238270777.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>97<br>Aging is a progressive phenomenon of losing physiological function, behavior and cognitive ability over time. Previous studies have pointed out that oxidative stress is an important factor that causes aging. Therefore, some previously shown antioxidative materials were chosen, including water extract of Longan flower (Dimocarpus longan Lour.) (L-W), water extract of mulberry (Morus alba Linn.) (M-W), water extract of roselle (Hibiscus sabdariffa Linn.) (R-W), water fraction from ethanol extract of embryo of Nelumbo nucufera Gaertn.(N-E-W), stilbene glycoside fr

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