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Dissertations / Theses on the topic 'STM1'

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Published: 4 June 2021
Last updated: 3 February 2022

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1

Ilina, Yulia. "Functions of the yeast protein Stm1 and its involvement in apoptotic cell death." [S.l. : s.n.], 2005.

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2

Balagopal, Vidya. "STM1 IS A NOVEL REGULATOR OF MESSENGER RNA TRANSLATION AND DEGRADATION IN SACCHAROMYCES CEREVISIAE." Diss., The University of Arizona, 2010. http://hdl.handle.net/10150/145717.

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In eukaryotes, regulation of translation and decay of messenger RNA are critical for fine-tuned control of gene expression. An important point of control is the key transition where mRNAs exit translation and assemble into a non-translating mRNP state that can accumulate in cytoplasmic granules such as P bodies and/or Stress granules. In the budding yeast Saccharomyces cerevisiae , the activators of decapping Dhh1 and Pat1 appear to promote the exit of mRNAs from translation. In my work, summarized below, I describe a new regulator of translation repression and mRNA degradation, Stm1, and its
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Gatsos, Xenia, and xgatsos@optusnet com au. "The development of live vectored vaccines targeting the alpha-toxin of Clostridium perfringens for the prevention of necrotic enteritis in poultry." RMIT University. Applied Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080212.142403.

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The Ą-toxin of Clostridium perfringens is a toxin involved in numerous diseases of humans and agriculturally important animals. One of these diseases is necrotic enteritis (NE), a sporadic enteric disease which affects avian species world-wide. This study involved the inactivation of alpha-toxin (Ą-toxin) for use as a potential vaccine candidate to combat NE in chickens, and other diseases caused by C. perfringens type A. During the course of this research a number of Ą-toxin recombinant proteins were developed through molecular inactivation of the Ą-toxin gene, plc. Proteins plc3
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ABREU, FERNANDA DE MELLO. "TIME-DOMAIN OPTICAL MULTIPLEXING IN STM-16, STM-64 AND STM-256 SYSTEMS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2001. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=2361@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>ALCATEL TELECOMUNICAÇÕES<br>Este trabalho tem como foco o up-grade da taxa de bits em enlaces ópticos através da tecnologia OTDM. Os sistemas analisados contemplam os up-grades das taxas de 2,48 Gbps para 10 Gbps e também da taxa de 10 Gbps para 40 Gbps. Para tal, foram introduzidos módulos de transmissão e recepção, capazes de utilizar arquiteturas quase totalmente ópticas. É avaliado então, através de simulações, o comportamento da arquitetura proposta em infra-estruturas de enlaces já instalados no Brasil, destacando os pontos mai
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Al, Badine Samir. "STMM soumission de travaux en mode messagerie /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37611499t.

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Lampe, Birgit [Verfasser]. "Transkranielle Einzelimpulsstimulation (sTMS) bei akustischer Verbgenerierung / Birgit Lampe." Köln : Deutsche Zentralbibliothek für Medizin, 2012. http://d-nb.info/1024715361/34.

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Cardoso, Aline Monticelli 1988. "Estudos sobre a internalização celular da STC1 humana." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314360.

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Orientador: Jörg Kobarg<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-27T05:39:09Z (GMT). No. of bitstreams: 1 Cardoso_AlineMonticelli_M.pdf: 19291466 bytes, checksum: 5920430c506c4670ca04da10ad934398 (MD5) Previous issue date: 2015<br>Resumo: A Stanniocalcina-1 (STC1) humana é uma glicoproteína homóloga a Stanniocalcina (STC) originalmente identificada como um hormônio regulador da homeostase de cálcio em peixes. A STC1 humana secretada atua em diferentes processos fisiológicos incluindo a angiogênese, a hipóxia e
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Holl, Christian [Verfasser], Markus [Akademischer Betreuer] Morgenstern, and Samir [Akademischer Betreuer] Lounis. "High frequency STM and spin polarized STM on magnetic vortices / Christian Holl ; Markus Morgenstern, Samir Lounis." Aachen : Universitätsbibliothek der RWTH Aachen, 2018. http://d-nb.info/1192217926/34.

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Azevedo, Cristina Maria Lourenço da Cunha Correia de. "Functional analysis of RAR1 and STG1 in disease resistance." Thesis, University of East Anglia, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399785.

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Troupes, Constantine. "The Role of STIM1 in Hypertrophy-Related Contractile Dysfunction." Diss., Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/403786.

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Biomedical Sciences<br>Ph.D.<br>Increases in cardiac afterload caused by disease conditions results in remodeling of heart structure by hypertrophy and alterations in the molecular regulation of contractile performance. These adaptations can be regulated by various Ca2+-dependent signaling processes. STIM1 is an important regulator of Ca2+ signaling in different cell types by sensing endoplasmic reticular Ca2+ levels and coupling to plasma membrane Orai channels. The role of STIM1 in heart is not well understood, given the robust Ca2+ regulatory machinery present within cardiac myocytes. Previ
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Walsh, Ciara. "The regulation of STIM1 translocation to the plasma membrane." Thesis, University of Liverpool, 2010. http://livrepository.liverpool.ac.uk/1482/.

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A rise in intracellular Ca2+ concentration is key to controlling both short term and long term Ca2+ dependent processes which include secretion, metabolism and gene expression, cell growth and proliferation. Store operated Ca2+ channels (SOCs), which are activated by the depletion of Ca2+ from internal Ca2+ stores, the main store being the endoplasmic reticulum (ER), are the major route for Ca2+ influx in non-excitable cell types. Stromal interacting molecule 1 (STIM1) is a Ca2+ sensing protein located in the endoplasmic reticulum (ER). Depletion of ER calcium stores triggers oligomerisation a
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Wiehlmann, Lutz. "Sequenzspezifizierte Transposonmutagenese (STM) in Pseudomonas aeruginosa." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=96511211X.

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Ruess, Frank Joachim Physics Faculty of Science UNSW. "Atomically controlled device fabrication using STM." Awarded by:University of New South Wales. Physics, 2006. http://handle.unsw.edu.au/1959.4/24855.

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We present the development of a novel, UHV-compatible device fabrication strategy for the realisation of nano- and atomic-scale devices in silicon by harnessing the atomic-resolution capability of a scanning tunnelling microscope (STM). We develop etched registration markers in the silicon substrate in combination with a custom-designed STM/ molecular beam epitaxy system (MBE) to solve one of the key problems in STM device fabrication ??? connecting devices, fabricated in UHV, to the outside world. Using hydrogen-based STM lithography in combination with phosphine, as a dopant source, and sil
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Deshpande, Aparna. "Atomistic interactions in STM atom manipulation." Ohio : Ohio University, 2007. http://www.ohiolink.edu/etd/view.cgi?ohiou169849272.

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Dixon, Richard. "STM studies of semiconducting metal oxides." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365728.

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Revenikiotis, Sackis (Athanasios). "Optimization of STM-tip preparation methods." Thesis, KTH, Materialfysik, MF (Stängd 20120101), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-30873.

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The Scanning Tunneling Microscope (STM) was invented by Gerd Binnig and Heinrich Rohrer and gave them the Nobel Prize in Physics 1986. STM can give us atomic resolution of a surface by applying a voltage between a very sharp tip (STM-tip) and the surface of a material that we want to examine. The STM-tip is moving over the surface and a computer is collecting the tunnel current in every single point to create a digital image. This diploma work is focused on the preparation of the STM-tip. The preparation method that is used is electrochemical etching of a tungsten wire. The sharper the STM-tip
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Wilson, Jon H. "Silicon surfaces : STM, theory and experiment." Thesis, University of Oxford, 1991. http://ora.ox.ac.uk/objects/uuid:64998ae3-9316-42b5-967f-da93ff2bfd6c.

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The fundamental atomic and electronic behaviour of clean silicon surfaces has been studied within a simple tight-binding picture of bonding in solids. Of the various contributions to the surface binding energy, the lowering in the promotion energy (i.e. rehybridization) which accompanies localized Jahn-Teller distortions has been identified as a major electronic driving force underlying the stability of silicon surfaces. The structure of Si(113) has been experimentally determined by the technique of scanning tunnelling microscopy (STM). Despite its high index, the Si(113) surface is found to b
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Clarke, A. R. H. "Quantitative STM imaging of metal surfaces." Thesis, University of Oxford, 1996. http://ora.ox.ac.uk/objects/uuid:68cbeba7-d283-498a-9435-b9587e7ef30a.

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Many deductions made about STM images are based upon the model of Tersoff and Hamann, in which images are given in principal by a combination of surface atomic positions and local charge density. There is a now a need for a fuller understanding of this technique in order to explain experimental evidence which indicates that the tip and sample can interact strongly during normal imaging. In order to investigate the fundamental STM imaging process, a method for deducing the tunnel barrier height has been developed which is based on corrugation height measurements of constant current topographs.
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Silva, Neto Francisco Miranda Soares da. "Rewriting Concurrent Haskell programs to STM." Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/11435.

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Dong, Yi. "Single site surface reactions : STM Studies." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/30204.

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La demande des composants chimiques énantiopurs dans le secteur pharmaceutique est une des forces qui motive la recherche dans la création des catalyseurs homochiraux à la surface. La catalyse hétérogène est une méthode prometteuse pour la fabrication des produits énantiopurs puisqu'elle porte des avantages tels que la facilité de la séparation des produits désirés, la réutilisation du catalyseur et l'adaptabilité dans différentes conditions de la production en continu. La réaction d'Orito est un des exemples de la réaction hétérogène énantiosélective la plus réussie. Elle concerne l'hydrogéna
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Vianna, Camila Pereira. "Papel da proteína STI1 na via de sinalização Rnd1 - p190RhoGAP." reponame:Repositório Institucional da UFPR, 2017. http://hdl.handle.net/1884/53519.

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Orientador : Prof. Dr. Silvio Marques Zanata<br>Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Biológicas, Programa de Pós-Graduação em Ciencias Biológicas (Microbiologia, Parasitologia e Patologia Básica). Defesa: Curitiba, 2017<br>Inclui referências : f. 55-60<br>Resumo: A proteína STI1 foi descrita como uma molécula relacionada ao estresse térmico de leveduras, e por isso é denominada Stress-Inducible Protein 1. Sua homóloga humana é a Hop (Heat-shock organizing protein). Ela tem expressão praticamente ubíqua e é encontrada em vesículas intracelulares, complexo d
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Shao, Jianfei. "STM/STS and BEES Study of Nanocrystals." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/10526.

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This work investigates the electronic properties of very small gold and semiconductor particles using Scanning Tunneling Microscopy/Spectroscopy (STM/STS) and Ballistic Electron Emission Spectroscopy (BEES). Complementary theoretical works were also performed. The first theoretical work was to calculate the quantized states in the CdS/HgS/CdS quantum-well-quantum-dot nanocrystals. An eight-band envelope function method was applied to this system. This method treats exactly the coupling between the conduction bands, the light-hole bands, the heavy-hole bands, and the spin-orbit split bands. The
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Liu, Jun. "Neo--- A new perspective on STM capacity." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5034.

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Exploring the word length effect from the perspective of information density, the current research extended previous findings on cross-linguistic differences in STM capacity with the development of a new strategy that has the potential to double ones digit span with minimal learning and a much shorter training period. Experiments have shown promising results and responses to training differed across language groups. The underlying mechanisms are explored and discussed in relation to strategy usage, capacity estimates and optimization of language systems.
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Martins, Bruno Vieira da Cunha. "Desenho e construção de um UHV-STM." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/277568.

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Orientador: Daniel Mario Ugarte<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Fisica Gleb Wataghin<br>Made available in DSpace on 2018-08-17T22:12:05Z (GMT). No. of bitstreams: 1 Martins_BrunoVieiradaCunha_D.pdf: 17693367 bytes, checksum: cd2b98fba2b0d91ed107d569050c937f (MD5) Previous issue date: 2011<br>Resumo: O estudo da estrutura de nanosistemas individuais requer o uso de equipamentos capazes de gerar imagens de sistemas com poucos átomos. No caso de nanopartículas metálicas produzidas por síntese química, uma questão relevante e ainda pouco estudada é a organiz
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Leandro, Silvana Castro [UNESP]. "Batimentos quânticos dependentes do SPIN via STM." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/91985.

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Made available in DSpace on 2014-06-11T19:25:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-06-28Bitstream added on 2014-06-13T19:07:22Z : No. of bitstreams: 1 leandro_sc_me_ilha.pdf: 1782827 bytes, checksum: 80c4f27095adfdf0cbd88b99966a75fa (MD5)<br>Neste trabalho investigou-se teoricamente a densidade local de estados (LDOS) sondada por uma ponta de STM de metais hospedando um átomo adsorvido e uma impureza subsuperficial. Modelamos o sistema por meio do Hamiltoniano de Anderson de duas impurezas. Utilizando-se do procedimento da equação de movimento nas funções de Green, deriva
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Leandro, Silvana Castro. "Batimentos quânticos dependentes do SPIN via STM /." Ilha Solteira, 2013. http://hdl.handle.net/11449/91985.

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Orientador: Antonio Carlos Ferreira Seridonio<br>Banca: Devaney Ribeiro do Carmo<br>Banca: Guillermo Gerardo Cabrera Oyarzun<br>Resumo: Neste trabalho investigou-se teoricamente a densidade local de estados (LDOS) sondada por uma ponta de STM de metais hospedando um átomo adsorvido e uma impureza subsuperficial. Modelamos o sistema por meio do Hamiltoniano de Anderson de duas impurezas. Utilizando-se do procedimento da equação de movimento nas funções de Green, derivamos expressões analíticas para a LDOS de dois tipos de hospedeiro: uma superfície metálica e um fio quântico. A LDOS revela osci
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Robertson, Derek. "Variable processing of flavours in rat STM." Thesis, University of St Andrews, 1985. http://hdl.handle.net/10023/14682.

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The research reported in this thesis examines factors that affect the willingness of rats to ingest novel flavour solutions. Emphasis is placed on the memorial processes assumed to underlie the decision as to whether or not a solution is "safe" to drink. Rats exhibit caution (neophobia) in consuming an unfamiliar (target) solution. This unconditional response to novelty habituates as the rat acquires experience with the target solution (provided that ingestion of the target solution has no noxious consequences!). Neophobia to the target solution may be restored, however, if another (distractor
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Pavelec, Jiří. "Vývoj lineárního posuvu pro UHV STM/AFM." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229812.

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The aim of this diploma thesis is to develop a linear positioning stage for Ultra High Vacuum (UHV) environment. Simple prototypes of the linear positioning stage were designed and incorporated as part of a multiaxis sample manipulator for a UHV Scanning Tunneling Microscopy / Atomic Force Microscopy (STM/AFM). Different types of position encoders and linear guideways are discussed. Implementation of the homodyne interferometer as an optimization tool for a slip-stick based linear stage is described. Scalar diffraction theory is used to model the diffraction grating optical position encoder be
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Lur, Gyorgy. "STIM1, Orai1 and store operated calcium entry in pancreatic acinar cells." Thesis, University of Liverpool, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539501.

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Saliba, Youakim. "Identification des partenaires de STIM1 dans le cœur normal et hypertrophié." Paris 6, 2012. http://www.theses.fr/2012PA066541.

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Nous avons déjà démontré un rôle important de STIM1 dans l’induction de l’hypertrophie cardiaque, mais l’identité des canaux STIM1 dépendants responsables de ce flux calcique pro-hypertrophique dans les cellules ventriculaires du rat reste à déterminer. Dans cette étude, nous avons développé une nouvelle méthode de transfert myocardique de gène non viral, en utilisant l’énergie des ultrasons, des liposomes et des injections pressurisées dans le myocarde du rat. Grâce à sa simplicité, son efficacité et sa faible immunogénicité, cette technique a produit un nombre suffisant de cellules transfect
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Gueder, Nahla. "sp²-Iminosugar-glucosidases inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine - induced antiproliferative, apoptotic and necrotic effects in breast cancer cells via targeting GRP78, Stim1 and Orai1." Thesis, Amiens, 2018. http://www.theses.fr/2018AMIE0033/document.

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L'altération de glycosylation est l'une des caractéristiques du cancer du sein. Ainsi le défaut de glycosylation affecte différentes protéines glycosylées responsables des différents processus cancéreux. Les canaux SOC (Store operated channels) constituent la voie majeure de l'entrée du calcium dans les cellules et sont impliqués dans la prolifération, la migration et la survie des cellules cancéreuses du sein. CO-OCS est un nouvel inhibiteur de la glycosylation avec plus de sélectivité vis-à-vis des α-glucosidases, et montre des activités anticancéreuses des cellules cancéreuses du sein, sans
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Le, Sueur Hélène. "Un AFM-STM cryogénique pour la physique mésoscopique." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2007. http://tel.archives-ouvertes.fr/tel-00261434.

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La spectroscopie électronique basée sur l'effet tunnel donne accès à la densité d'états des électrons (DoS) dans les matériaux conducteurs, et renseigne ainsi en détail sur leurs propriétés électroniques. <br />Au cours de cette thèse, nous avons développé un microscope permettant d'effectuer la spectroscopie tunnel résolue spatialement (10 nm) de nanocircuits individuels, avec une résolution en énergie inégalée (10 µeV). Cet appareil combine les fonctions de Microscopie par Force Atomique (mode AFM) et de spectroscopie Tunnel locale (mode STM), et fonctionne à 30 mK. Dans le mode AFM, la topo
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Pham, Van Dong. "STM characterization of functionalized carbon nanotubes and graphene." Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCC245.

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Dans cette thèse, nous avons étudié l'interaction entre des molécules organiques et des nanomatériaux de carbone. En utilisant un microscope à effet tunnel (STM) à basse température et sous ultra-vide, nous avons mesuré les propriétés de molécules de porphyrine physisorbées sur du graphène ou des nanotubes de carbone. Nous avons d'abord étudié l'injection d'électrons dans le graphène sur des défauts (joints de grains et atomes d'azote insérés). Une étude d'états image résonants nous a également permis de mettre en évidence une variation locale du travail de sorite dans le graphène dopé. Nous a
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Vinet, Maud. "Etude par stm de nanostructures supraconductrices par proximite." Université Joseph Fourier (Grenoble), 2001. http://www.theses.fr/2001GRE10047.

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Cette these a ete motivee par le desir d'etudier l'effet de proximite entre un metal normal (n) et un supraconducteur (s). Pour cela, nous avons construit un microscope a effet tunnel (stm) pour mesurer la densite d'etats electroniques locale d'un metal. Celui-ci fonctionne a 100 mk dans un cryostat a dilution renverse. Pour respecter la philosophie de ce cryostat original, le stm est thermalise par contacts mecaniques sur la boite de melange sans gaz d'echange. Avant de coupler le stm a la dilution, nous avons procede a une mise au point prealable dans un cryostat a 4he a des temperatures com
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Voňka, Jakub. "Návrh a ověření nízkoteplotní části UHV - STM mikroskopu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230611.

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The diploma thesis addresses the design and experimental verification of cooling system and low temperature part of UHV - STM working in temperature range of 20K - 300K. Due to the demand of variable temperature, the flow cooling system with cryogenic (~5 K) helium (He) is used. Two variants of the low temperature part of the microscope are studied. First the version with cooling only the sample holder, and second with cooling of the whole STM. Designed cooling system consists of He flow cryostat allowing to connect it to the Dewar vessel with liquid helium (LHe) using a low-loss transfer line
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Dao, Tomáš. "Návrh nosné platformy pro nízkoteplotní UHV STM mikroskop." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231317.

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Diploma thesis deals with the design of a vibration isolated platform for low temperature scanning tunneling microscope working under ultra high vacuum (UHV STM). Cooling of the microscope is done by liquid helium using a flow cryostat designed in Institute of Scientific Instruments of the AS CR. In the thesis, general requirements of designing of an ultra high vacuum compatible devices are discussed, as well as the ways of vibrational isolation and damping. Also some ways how to restrict the transfer of vibration between vacuum devices and surroundings are mentioned. This knowledge is then ap
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Clark, Kendal W. "STM Study of Molecular and Biomolecular Electronic Systems." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1282363151.

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McElroy, Cameron Shea. "The Role of SULT2 ST1 in Zebrafish Development." University of Toledo / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1273786802.

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Willis, Mary L. "STM Studies of Oxygen Etching of Silicon Surfaces." VCU Scholars Compass, 2005. http://scholarscompass.vcu.edu/etd/1008.

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This study uses atomic force microscopy (AFM) to investigate the oxygen etching behavior of the following silicon surface orientations: (001), (111), (113), (5 5 12) and (112). Most etching was performed at sample temperatures between 650 °C and 800 °C, at pressures of 3.3×10-7 and 1.5×10-7 Torr, and at an exposure of 200 L. Surface orientation strongly influences the morphology resulting from extended etching. The surface orientations that are stable against etching and remain flat include Si(001), Si(111), and Si(113). Such surfaces also include island structures, which result from etching a
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Premsler, Thomas [Verfasser], Albert [Akademischer Betreuer] Sickmann, and Jan Georg [Gutachter] Hengstler. "Mass spectrometry based interaction study of the STIM1 and VASP proteins : (Massenspektrometrie-basierte Interaktionsstudie der Proteine STIM1 und VASP) / Thomas Premsler. Betreuer: Albert Sickmann. Gutachter: Jan Georg Hengstler." Dortmund : Universitätsbibliothek Dortmund, 2012. http://d-nb.info/1110892373/34.

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41

Schmid, Andreas B. "The adaptor protein Sti1/Hop connects the Hsp70 and Hsp90 chaperone cycle /." München : Verl. Dr. Hut, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018860584&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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42

Mateo, Montalcini Solange A. "AGC kinase Sta1 is a virulence determinant in the rice blast fungus." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531838.

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43

Ahmed, Jubed Omee. "Characterisation of the roles of Poz1 and Stn1 at Schizosaccharomyces pombe telomeres." Thesis, University of Sussex, 2014. http://sro.sussex.ac.uk/id/eprint/48855/.

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Telomeres protect the ends of chromosomes from the activity of DNA repair machinery and provide a solution to the end-replication problem. In humans, the core protein complex located at telomeres is known as shelterin and consists of six protein subunits. Although variation is seen in the telomeric complex between species, in fission yeast the complex has notable similarities to that of humans. Separately to shelterin, the CST complex (Cdc13/Stn1/Ten1) is conserved in budding yeast, plants and mammals and is thought to negatively regulate telomerase, in addition to being required for telomere
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44

Sreedharan, Pillai Sreerekha. "Insight into Stc1-interactions bridging RNAi and chromatin modification in Schizosaccharomyces pombe." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28733.

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Compact heterochromatin is essential for genome stability and hence cell survival. Studies in many organisms including humans underline the importance of pericentromeric heterochromatin in centromere function. Fission yeast centromeres share a common structural organisation with those of their metazoan counterparts. The fission yeast model has been pivotal in understanding many key events in the pathway leading to the assembly of pericentromeric heterochromatin. In particular, studies in this system have revealed that the RNA interference (RNAi) pathway connects with the chromatin modification
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45

Monteros, Juan Carlos. "Conservação evolutiva da proteína STI1 nas espécies Mus musculus e Danio rerio." reponame:Repositório Institucional da UFPR, 2009. http://hdl.handle.net/1884/20677.

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Cao, Hang [Verfasser]. "Effect of STIM1/2 and of Ceritinib on Platelet Function / Hang Cao." Tübingen : Universitätsbibliothek Tübingen, 2021. http://d-nb.info/1234450763/34.

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47

Frappier, Maude. "MURC est un partenaire d’interaction de STIM1 impliqué dans la signalisation calcique." Mémoire, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/8332.

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Dans les cardiomyocytes, la concentration intracellulaire de Ca2+ doit être finement régulée pour maintenir l’homéostasie calcique. La protéine Stromal interaction molecule 1 (STIM1), qui joue un rôle important dans le maintien des niveaux intracellulaires de Ca2+ des cellules non excitables en opérant l’entrée capacitative de Ca2+ (SOCE), est aussi présente dans les cardiomyocytes. Plusieurs études démontrent que STIM1 et le SOCE jouent un rôle important dans le développement de l’hypertrophie des cardiomyocytes. De plus, récemment, un nouveau rôle de STIM1 a commencé à émerger. STIM1 pourrai
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Olthoff, Silke. "High temperature scanning tunnelling microscopy of adsorbate induced phase transitions." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264547.

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吳誼暉 and Yee-fai Ng. "Optimization of etching parameters for STM tips and an STM study of SiC (0001) [square root]3 x [square root]3 reconstruction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B29797834.

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Ng, Yee-fai. "Optimization of etching parameters for STM tips and an STM study of SiC (0001) [square root]3 x [square root]3 reconstruction /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20567583.

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