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Journal articles on the topic 'Stochastic lifespan'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Bylino, Oleg V., Anna A. Ogienko, Mikhail A. Batin, Pavel G. Georgiev, and Evgeniya S. Omelina. "Genetic, Environmental, and Stochastic Components of Lifespan Variability: The Drosophila Paradigm." International Journal of Molecular Sciences 25, no. 8 (2024): 4482. http://dx.doi.org/10.3390/ijms25084482.

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Lifespan is a complex quantitative trait involving genetic and non-genetic factors as well as the peculiarities of ontogenesis. As with all quantitative traits, lifespan shows considerable variation within populations and between individuals. Drosophila, a favourite object of geneticists, has greatly advanced our understanding of how different forms of variability affect lifespan. This review considers the role of heritable genetic variability, phenotypic plasticity and stochastic variability in controlling lifespan in Drosophila melanogaster. We discuss the major historical milestones in the

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Stubbings, Garrett, and Andrew Rutenberg. "Network topologies for maximal organismal health span and lifespan." Chaos: An Interdisciplinary Journal of Nonlinear Science 33, no. 2 (2023): 023124. http://dx.doi.org/10.1063/5.0105843.

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The population dynamics of human health and mortality can be jointly captured by complex network models using scale-free network topology. To validate and understand the choice of scale-free networks, we investigate which network topologies maximize either lifespan or health span. Using the Generic Network Model (GNM) of organismal aging, we find that both health span and lifespan are maximized with a “star” motif. Furthermore, these optimized topologies exhibit maximal lifespans that are not far above the maximal observed human lifespan. To approximate the complexity requirements of the under

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Yang, Yifan, Ana L. Santos, Luping Xu, Chantal Lotton, François Taddei, and Ariel B. Lindner. "Temporal scaling of aging as an adaptive strategy of Escherichia coli." Science Advances 5, no. 5 (2019): eaaw2069. http://dx.doi.org/10.1126/sciadv.aaw2069.

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Natural selection is thought to shape the evolution of aging patterns, although how life-history trajectories orchestrate the inherently stochastic processes associated with aging is unclear. Tracking clonal growth-arrested Escherichia coli cohorts in an homogeneous environment at single-cell resolution, we demonstrate that the Gompertz law of exponential mortality characterizes bacterial lifespan distributions. By disentangling the rate of aging from age-independent components of longevity, we find that increasing cellular maintenance through the general stress pathway reduces the aging rate

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Klimavičienė, Aušra. "STOCHASTIC OPTIMIZATION OF HEURISTIC METHOD RULE TO DETERMINE ASSET ALLOCATION TO RETIREMENT PORTFOLIO / STOCHASTINIS EURISTINIO METODO TAISYKLĖS PENSIJOS PORTFELIO SUDĖČIAI NUSTATYTI OPTIMIZAVIMAS." Business: Theory and Practice 12, no. 1 (2011): 92–98. http://dx.doi.org/10.3846/btp.2011.10.

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The article examines the problem of determining asset allocation to sustainable retirement portfolio. The article attempts to apply heuristic method – 100 minus age in stocks rule – to determine asset allocation to sustainable retirement portfolio. Using dynamic stochastic simulation and stochastic optimization techniques the optimization of heuristic method rule is presented and the optimal alternative to „100“ is found. Seeking to reflect the stochastic nature of stock and bond returns and the human lifespan, the dynamic stochastic simulation models incorporate both the stochastic returns an

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Klimavičienė, Aušra. "Stochastic Optimization of Heuristic Method Rule to Determine Asset Allocation to Retirement Portfolio." Business: Theory and Practice 12, no. (1) (2011): 92–98. https://doi.org/10.3846/btp.2011.10.

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The article examines the problem of determining asset allocation to sustainable retirement portfolio. The article attempts to apply heuristic method – 100 minus age in stocks rule – to determine asset allocation to sustainable retirement portfolio. Using dynamic stochastic simulation and stochastic optimization techniques the optimization of heuristic method rule is presented and the optimal alternative to "100" is found. Seeking to reflect the stochastic nature of stock and bond returns and the human lifespan, the dynamic stochastic simulation models incorporate both the stochastic returns an

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Šikić, Hrvoje, Yanrong Shi, Snježana Lubura, and Steven Bassnett. "A full lifespan model of vertebrate lens growth." Royal Society Open Science 4, no. 1 (2017): 160695. http://dx.doi.org/10.1098/rsos.160695.

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The mathematical determinants of vertebrate organ growth have yet to be elucidated fully. Here, we utilized empirical measurements and a dynamic branching process-based model to examine the growth of a simple organ system, the mouse lens, from E14.5 until the end of life. Our stochastic model used difference equations to model immigration and emigration between zones of the lens epithelium and included some deterministic elements, such as cellular footprint area. We found that the epithelial cell cycle was shortened significantly in the embryo, facilitating the rapid growth that marks early le

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Klimavičienė, Aušra. "Using Dynamic Stochastic Simulation to Determine Asset Allocation of Sustainable Retirement Portfelio for a Stochastic Lifetime." Business: Theory and Practice 11, no. (4) (2010): 381–86. https://doi.org/10.3846/btp.2010.41.

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The article examines the problem of determining asset allocation of sustainable retirement portfolio. Former researches used to analyse the fixed retirement planning horizon. Seeking to reflect the stochastic nature of the human lifespan the dynamic stochastic simulation models used for calculations are updated to incorporate the probability of living another year based on Lithuanians ' mortality tables. The article presents the attempts to analyse the methods used to identify the optimal asset allocation of retirement portfolio using dynamic stochastic simulation techniques. The research resu

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Zapién-Campos, Román, Michael Sieber, and Arne Traulsen. "Stochastic colonization of hosts with a finite lifespan can drive individual host microbes out of equilibrium." PLOS Computational Biology 16, no. 11 (2020): e1008392. http://dx.doi.org/10.1371/journal.pcbi.1008392.

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Macroorganisms are inhabited by microbial communities that often change through the lifespan of an individual. One of the factors contributing to this change is colonization from the environment. The colonization of initially microbe-free hosts is particularly interesting, as their microbiome depends entirely on microbes of external origin. We present a mathematical model of this process with a particular emphasis on the effect of ecological drift and a finite host lifespan. Our results indicate the host lifespan becomes especially relevant for short-living organisms (e.g. Caenorhabditis elega

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9

Machek, Ondrej, and Jiri Hnilica. "A Stochastic Model of Corporate Lifespan Based on Corporate Credit Ratings." International Journal of Engineering Business Management 5 (January 1, 2013): 45. http://dx.doi.org/10.5772/56918.

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Credit rating agencies and corporate lifecycles have been a subject of interest for practitioners and academics during the recent period of worldwide economic and debt crises. In this article, we examine what corporate lifespan the credit rating agencies predict. We employ the reliability theory commonly used in engineering and solve a Markov model based on the credit rating transition matrices issued by the Standard & Poor's rating agency. The results show that every company will eventually default in the long-term. However, the mean time to default differs according to the initial condit

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Caswell, Hal. "The contributions of stochastic demography and social inequality to lifespan variability." Demographic Research 49 (August 22, 2023): 309–54. http://dx.doi.org/10.4054/demres.2023.49.13.

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11

Vantha, P., P. Pandiyan, and V. S. Venkatesh Kumar. "A STOCHASTIC MODEL FOR LUNG CANCER." Advances in Mathematics: Scientific Journal 11, no. 10 (2021): 943–54. http://dx.doi.org/10.37418/amsj.11.10.10.

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Cancer is one of the most common health problems in the world today. A rapidly growing concern for millions of people around the world is the overall risk of cancer. Cancer is emerging as a major problem globally, both in more developed and less developed countries. The study showed that a person predisposed to lung cancer increases tumor growth, with exposure shortening the expected lifespan. The present study estimates that tumor development for carcinoma rapidly increases the threshold level of the infected individual. Once a person is infected, the tumor cells proliferate, and once infecte

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Li, Dong, Zhou-Lian Zheng, Rui Yang, and Peng Zhang. "Analytical Solutions for Stochastic Vibration of Orthotropic Membrane under Random Impact Load." Materials 11, no. 7 (2018): 1231. http://dx.doi.org/10.3390/ma11071231.

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Orthotropic membrane materials have been applied in the numerous fields, such as civil engineering, space and aeronautics, and mechanical engineering, among others. During their serving lifespan, these membranes are always facing strong stochastic vibrations induced by the random impact load such as hail, heavy rain, and noise, among others. In this paper, the stochastic vibration problem of orthotropic membrane subjected to random impact load is investigated. The statistical characteristics of random impact load are initially obtained based on the stochastic pulse theory. Then, the Von Karman

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Cianflone, Eleonora, Michele Torella, Cristina Chimenti, et al. "Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon?" Oxidative Medicine and Cellular Longevity 2019 (February 7, 2019): 1–19. http://dx.doi.org/10.1155/2019/5813147.

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Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose prevalence dramatically increases with increasing age reaching epidemic proportions. In the elderly, pathologic cellular and molecular changes in cardiac tissue homeostasis and response to injury result in progressive deteriorations in the structure and function of the heart. Although the phenotypes of cardiac aging have been the subject of intense study, the recent discovery that cardiac homeostasis during mammalian lifespan is maintained and regulated by regenerative events associated with endogeno

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Komijani, Mansoure, and Mohsen Sheikh Sajadieh. "An integrated planning approach for perishable goods with stochastic lifespan: Production, inventory, and routing." Cleaner Logistics and Supply Chain 12 (September 2024): 100163. http://dx.doi.org/10.1016/j.clscn.2024.100163.

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15

Avraam, Demetris, Joao Pedro de Magalhaes, and Bakhtier Vasiev. "A mathematical model of mortality dynamics across the lifespan combining heterogeneity and stochastic effects." Experimental Gerontology 48, no. 8 (2013): 801–11. http://dx.doi.org/10.1016/j.exger.2013.05.054.

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Pichugin, Boris J., Nikolai V. Pertsev, Valentin A. Topchii, and Konstantin K. Loginov. "Stochastic modelling of age-structured population with time and size dependence of immigration rate." Russian Journal of Numerical Analysis and Mathematical Modelling 33, no. 5 (2018): 289–99. http://dx.doi.org/10.1515/rnam-2018-0024.

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Abstract A stochastic age-structured population model with immigration of individuals is considered. We assume that the lifespan of each individual is a random variable with a distribution function which may differ fromthe exponential one. The immigration rate of individuals depends on the time and total population size. Upper estimates for the mean and variance of the population size are established based on the theory of branching processes with constant immigration rate. A Monte Carlo simulation algorithm of population dynamics is developed. The results of numerical experiments with the mod

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Chen, Ting, Zhengyu Liu, Ling Ju, Yongling Lu, and Shike Wei. "Improved Bayes-Based Reliability Prediction of Small-Sample Hall Current Sensors." Machines 12, no. 9 (2024): 618. http://dx.doi.org/10.3390/machines12090618.

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As a type of magnetic sensor known for its high reliability and long lifespan, the reliability issues of Hall current sensors have attracted attention in fields such as electromagnetic compatibility. However, there is still a lack of sufficient failure data for reliability prediction. Therefore, a small-sample reliability prediction method based on the improved Bayes method is proposed. Firstly, the pseudo-failure lifespan data are acquired through the accelerated degradation testing of Hall current sensors subjected to temperature and humidity stressors, and the life is examined by the Weibul

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Bentley, R. Alexander, and Stephen J. Shennan. "Cultural Transmission and Stochastic Network Growth." American Antiquity 68, no. 3 (2003): 459–85. http://dx.doi.org/10.2307/3557104.

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Archaeological theory has traditionally presupposed the existence of “battleship curves” in stylistic evolution, with little understanding about what governs the width (variant frequency) or length (variant lifespan) of these curves. In terms of these variables, we propose that there is a testable difference between independent decisions, unbiased transmission, and biased transmission in cultural evolution. We expect independent decision making to be represented by an exponential distribution of variant prevalence in the population. In contrast, unbiased transmission tends to be characterized

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Falbo, Paolo, Juri Hinz, Piyachat Leelasilapasart, and Cristian Pelizzari. "A Computational Approach to Sequential Decision Optimization in Energy Storage and Trading." Journal of Risk and Financial Management 14, no. 6 (2021): 235. http://dx.doi.org/10.3390/jrfm14060235.

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Due to recent technical progress, battery energy storages are becoming a viable option in the power sector. Their optimal operational management focuses on load shift and shaving of price spikes. However, this requires optimally responding to electricity demand, intermittent generation, and volatile electricity prices. More importantly, such optimization must take into account the so-called deep discharge costs, which have a significant impact on battery lifespan. We present a solution to a class of stochastic optimal control problems associated with these applications. Our numerical technique

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Hosseini, Seyed Amir, Rui Wu, and Saeed Peyghami. "Simulation-Based Assessment of Vibration Effects on IGBT Module Lifetime in Wind Turbines Through Modal and Random Vibration Analysis." Applied Sciences 15, no. 6 (2025): 3324. https://doi.org/10.3390/app15063324.

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This study explores the effect of vibrations generated by wind turbines on the lifespan of the IGBT module. Since wind turbines operate under varying dynamic loads, they produce vibrations that might influence the performance and longevity of electronic components like IGBTs. To investigate this concern, a modal analysis was carried out using the finite element analysis (FEA) in ANSYS to identify the natural frequencies of the module. These frequencies were then compared with typical load frequencies encountered in wind turbine operations. Furthermore, random vibration analysis, incorporating

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Tuljapurkar, Shripad, Jean-Michel Gaillard, and Tim Coulson. "From stochastic environments to life histories and back." Philosophical Transactions of the Royal Society B: Biological Sciences 364, no. 1523 (2009): 1499–509. http://dx.doi.org/10.1098/rstb.2009.0021.

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Environmental stochasticity is known to play an important role in life-history evolution, but most general theory assumes a constant environment. In this paper, we examine life-history evolution in a variable environment, by decomposing average individual fitness (measured by the long-run stochastic growth rate) into contributions from average vital rates and their temporal variation. We examine how generation time, demographic dispersion (measured by the dispersion of reproductive events across the lifespan), demographic resilience (measured by damping time), within-year variances in vital ra

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Buire, Jérôme, Frédéric Colas, Jean-Yves Dieulot, and Xavier Guillaud. "Stochastic Optimization of PQ Powers at the Interface between Distribution and Transmission Grids." Energies 12, no. 21 (2019): 4057. http://dx.doi.org/10.3390/en12214057.

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This paper addresses the volt-var control of distribution grids embedding many distributed generators (DGs). Specifically, it focuses on the compliance of powers to specified PQ diagrams at the high voltage/medium voltage (HV/MV) interface while the voltages remain well controlled. This is achieved using a two-stage optimization corresponding to two different classes of actuators. The tap position of capacitor banks is selected on a daily basis, given a stochastic model of the input powers prediction, which allows infrequent actuation and increases the device lifespan. In a second stage, a con

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Gontis, Vygintas. "Modeling Double Stochastic Opinion Dynamics with Fractional Inflow of New Opinions." Fractal and Fractional 8, no. 9 (2024): 513. http://dx.doi.org/10.3390/fractalfract8090513.

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Our recent analysis of empirical limit order flow data in financial markets reveals a power-law distribution in limit order cancellation times. These times are modeled using a discrete probability mass function derived from the Tsallis q-exponential distribution, closely aligned with the second form of the Pareto distribution. We elucidate this distinctive power-law statistical property through the lens of agent heterogeneity in trading activity and asset possession. Our study introduces a novel modeling approach that combines fractional Lévy stable motion for limit order inflow with this powe

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Mode, Charles J., Towfique Raj, and Candace K. Sleeman. "Simulating the Emergence and Survival of Mutations Using a Self Regulating Multitype Branching Processes." Journal of Probability and Statistics 2011 (2011): 1–39. http://dx.doi.org/10.1155/2011/867493.

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It is difficult for an experimenter to study the emergence and survival of mutations, because mutations are rare events so that large experimental population must be maintained to ensure a reasonable chance that a mutation will be observed. In his famous book,The Genetical Theory of Natural Selection, Sir R. A. Fisher introduced branching processes into evolutionary genetics as a framework for studying the emergence and survival of mutations in an evolving population. During the lifespan of Fisher, computer technology had not advanced to a point at which it became an effective tool for simulat

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Mathers, John C. "Nutrition and ageing: knowledge, gaps and research priorities." Proceedings of the Nutrition Society 72, no. 2 (2013): 246–50. http://dx.doi.org/10.1017/s0029665112003023.

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Over the past two centuries human life expectancy has increased by nearly 50 years. Genetic factors account for about one-third of the variation in life expectancy so that most of the inter-individual variation in lifespan is explained by stochastic and environmental factors, including diet. In some model organisms, dietary (energy) restriction is a potent, and highly reproducible, means of increasing lifespan and of reducing the risk of age-related dysfunction although whether this strategy is effective in human subjects is unknown. This is ample evidence that the ageing process is plastic an

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Campuzano-Bolarín, Marín-García, Moreno-Nicolás, Bogataj, and Bogataj. "Supply Chain Risk of Obsolescence at Simultaneous Robust Perturbations." Sustainability 11, no. 19 (2019): 5484. http://dx.doi.org/10.3390/su11195484.

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The earlier planning methods of supply chains (SC) in the skeleton of the extended material requirements planning (EMRP), where the time horizon of the reverse Laplace is infinite, were not convenient to estimate the impact of the technical obsolescence of the product or technology involved, which has economic, environmental, and social consequences. Therefore, the perturbations of timing are presented until the possible obsolescence, with parallel execution of the network simulation model (NSM) to evaluate the impact of the finite lifespan on the value of the chain. The EMRP, as well as the N

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Baptista, Daniel, and Nuno Brites. "Modelling French and Portuguese Mortality Rates with Stochastic Differential Equation Models: A Comparative Study." Mathematics 11, no. 22 (2023): 4648. http://dx.doi.org/10.3390/math11224648.

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In recent times, there has been a notable global phenomenon characterized by a double predicament arising from the concomitant rise in worldwide life expectancy and a significant decrease in birth rates. The emergence of this phenomenon has posed a significant challenge for governments worldwide. It not only poses a threat to the continued viability of state-funded welfare programs, such as social security, but also indicates a potential decline in the future workforce and tax revenue, including contributions to social benefits. Given the anticipated escalation of these issues in the forthcomi

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Burnaevskiy, Nikolay, Bryan Sands, Soo Yun, and Alexander Mendenhall. "IN VIVO ANALYSIS OF REPORTER ALLELES REVEALS INCREASED VARIABILITY OF GENE EXPRESSION IN CELLS AND ANIMALS WITH AGE." Innovation in Aging 3, Supplement_1 (2019): S101. http://dx.doi.org/10.1093/geroni/igz038.380.

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Abstract As a major risk factor for a multitude of chronic diseases aging is being increasingly recognized as a necessary therapeutic target for preventive medicine. Yet, despite tremendous progress in our understanding of the genetic determinants of longevity, proximal causes of aging remain incompletely understood. In part, this may be due to a plethora of factors, such as various types of stochastic macromolecular damage that affect individual cells and individual animals. Indeed, recent studies point to an increase of cell-to-cell variability in gene expression within old tissues, supporti

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Lieberman, Diana, Milton Lieberman, Gary Hartshorn, and Rodolfo Peralta. "Growth rates and age-size relationships of tropical wet forest trees in Costa Rica." Journal of Tropical Ecology 1, no. 2 (1985): 97–109. http://dx.doi.org/10.1017/s026646740000016x.

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ABSTRACTDiameter growth rates and age-size relationships are reported for 45 abundant tree species and one liana in tropical wet forest at La Selva, Costa Rica. Thirteen-year increments in each species were analysed using growth simulation, a stochastic technique which projects growth trajectories.Median growth rates ranged from 0.35 mm yr-1 (Anaxagorea crassipetala) to 13.41 mm yr-1) (Stryphnodendron excelsum). Maximum ranges ranged from 0.95 mm yr-1 (Quararibea brac-teolosa) to 14.62 mm yr-1 (Hernandia didymanthera). Minimum rates ranged from zero growth (Capparis pittieri, Colubrina spinosa

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Pélissier, Aurélien, Youcef Akrout, Katharina Jahn , et al. "Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts." Cells 9, no. 6 (2020): 1448. http://dx.doi.org/10.3390/cells9061448.

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Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs where B cells proliferate, differentiate, and mutate their antibody genes in response to the presence of foreign antigens. Through the GC lifespan, interclonal competition between B cells leads to increased affinity of the B cell receptors for antigens accompanied by a loss of clonal diversity, although the mechanisms underlying clonal dynamics are not completely understood. We present here a multi-scale quantitative model of the GC reaction that integrates an intracellular component, accounting for the ge

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BIECEK, PRZEMYSŁAW, and STANISŁAW CEBRAT. "FLUCTUATIONS, ENVIRONMENT, MUTATIONS ACCUMULATION AND AGEING." International Journal of Modern Physics C 17, no. 06 (2006): 923–31. http://dx.doi.org/10.1142/s0129183106009369.

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We present a model of evolution of the age structured population based on the Monte Carlo method. We have assumed that the health status of an individual is described by variance of its fluctuations. Each expressed deleterious mutation increases the fluctuations. Additionally, the fluctuations of the environment are superimposed on the fluctuations of individuals in the population. An individual dies if the combination of both stochastic processes trespass the limit (level of homeostasis) set as the model parameter. The genes are switched on chronologically, what leads to accumulating defectiv

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Al-Johani, Hanan, Julfikar Haider, Julian Satterthwaite, Marcia Borba, and Nick Silikas. "A Comprehensive Review of the Multifaceted Characterisation Approaches of Dental Ceramics." Prosthesis 6, no. 5 (2024): 1055–90. http://dx.doi.org/10.3390/prosthesis6050077.

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Ceramic dental restorative materials have growing popularity, albeit their brittle and stochastic nature are acknowledged shortcomings that impact the prosthesis lifespan. The mechanical performance of ceramics is dominated by the constitutional microstructural and fracture toughness mechanisms, as well as externally applied triggers. Thus, there is ongoing expanding research in the sphere of ceramic material engineering and thermal refinement, addressing concerns regarding toughness, machinability, reliability, stainability, and biodegradation. While the current trend in dental ceramic manufa

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Nikolopoulos, Dionysios, Panagiotis Kossieris, Ioannis Tsoukalas, and Christos Makropoulos. "Stress-Testing Framework for Urban Water Systems: A Source to Tap Approach for Stochastic Resilience Assessment." Water 14, no. 2 (2022): 154. http://dx.doi.org/10.3390/w14020154.

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Optimizing the design and operation of an Urban Water System (UWS) faces significant challenges over its lifespan to account for the uncertainties of important stressors that arise from population growth rates, climate change factors, or shifting demand patterns. The analysis of a UWS’s performance across interdependent subsystems benefits from a multi-model approach where different designs are tested against a variety of metrics and in different times scales for each subsystem. In this work, we present a stress-testing framework for UWSs that assesses the system’s resilience, i.e., the degree

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Pelosi, Dario, Frederico Gallorini, Giacomo Alessandri, and Linda Barelli. "A Hybrid Energy Storage System Integrated with a Wave Energy Converter: Data-Driven Stochastic Power Management for Output Power Smoothing." Energies 17, no. 5 (2024): 1167. https://doi.org/10.3390/en17051167.

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Beyond solar and wind energy, wave energy is gaining great interest due to its very high theoretical potential, although its stochastic nature causes intermittent and fluctuating power production. Energy storage system (ESS) integration to wave energy converter (WEC) plants represents a promising solution to mitigate this issue. To overcome the technological limits of the single storage devices, the hybridization of complementary ESSs represents an effective solution, extending the operating range over different timeframes. This paper analyzes the benefits of Li-ion battery–supercapacito

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Arias-Cazco, Diego, Heraldo Rozas, Diego Jimenez, Marcos E. Orchard, and Claudio Estevez. "Unifying Criteria for Calculating the Levelized Cost of Driving in Electro-Mobility Applications." World Electric Vehicle Journal 13, no. 7 (2022): 119. http://dx.doi.org/10.3390/wevj13070119.

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The Levelized Cost of Driving (LCOD) calculates how much it costs to drive a vehicle, per kilometer, over the vehicle lifespan, and it is typically measured in USD/km. LCOD has been widely applied to assess and compare the performance of Electric Vehicles (EVs) and Internal Combustion engine Vehicles (ICVs). Unfortunately, there is no common methodology to establish how to compute LCOD. As authors use different criteria to determine which elements are relevant in LCOD, it is difficult to compare results. To overcome this issue, we re-introduce the LCOD concept, where the most relevant expendit

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Zhang, Xuexia, Zixuan Yu, and Weirong Chen. "Life Prediction Based on D-S ELM for PEMFC." Energies 12, no. 19 (2019): 3752. http://dx.doi.org/10.3390/en12193752.

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The proton exchange membrane fuel cell (PEMFC) is an extremely clean and efficient power generation device. However, its limited lifespan has restricted the large-scale commercial development of PEMFCs. Life prediction is a promising solution for the further life extension of PEMFCs. In this paper, D-S ELM(DWT-SaDE ELM), define as, an enhanced extreme learning machine (ELM) optimized by discrete wavelet transform (DWT) and self-adaptive differential evolutionary algorithm (SaDE), is proposed to predict the remaining useful life (RUL) of PEMFCs. In D-S ELM, DWT is employed to extract available

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Nagy-Kovács, Zsuzsanna, Balázs László, Elek Simon, and Ernő Fleit. "Operational Strategies and Adaptation of RBF Well Construction to Cope with Climate Change Effects at Budapest, Hungary." Water 10, no. 12 (2018): 1751. http://dx.doi.org/10.3390/w10121751.

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The objective of this paper is to give an overview on the Hungarian experience of river bank filtration (RBF) systems. The study addresses the conflict, which arises between the stochastic character of river water quantity and quality, and the required standard of drinking-water supply. Trends in water levels, flow, and water quality are discussed, along with technical measures and operational rules that were developed for implementation of RBF systems. This paper also provides an overview of the average lifespan of the wells and operational strategies. The emerging reconstruction and recondit

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Ortega-Ferrusola, C., L. Anel-López, P. Martín-Muñoz, et al. "Computational flow cytometry reveals that cryopreservation induces spermptosis but subpopulations of spermatozoa may experience capacitation-like changes." Reproduction 153, no. 3 (2017): 293–304. http://dx.doi.org/10.1530/rep-16-0539.

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The reduced lifespan of cryopreserved spermatozoa in the mare reproductive tract has been attributed to both capacitative and apoptotic changes. However, there is a lack of studies investigating both phenomena simultaneously. In order to improve our knowledge in this particular point, we studied in raw and frozen-thawed samples apoptotic and capacitative markers using a wide battery of test based in flow cytometry. Apoptotic markers evaluated were caspase 3 activity, externalization of phosphatidylserine (PS), and mitochondrial membrane potential. Markers of changes resembling capacitation wer

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Muhammad Arsalan Ali Sajid, Muhammad Hassan, and Ayesha. "An overview of recent advancements in anti-aging medicines." World Journal of Advanced Research and Reviews 14, no. 1 (2022): 144–50. http://dx.doi.org/10.30574/wjarr.2022.14.1.0244.

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The phenomenon of aging is most common to all living organisms and its definition is the loss or reduction of the ability to reproduce offspring and the slowly decrease in physical fitness. The current aging population is considered to be a major burden of the 21st century. Therefore, in order to slow the process of aging and maintain the health of the elderly, the discovery of new antiaging medicine remains a top priority. Several well-known researchers are working on this issue which is considered to be a multi-billions of dollars industry in future. Institutes like CRG with scientists like

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Fregonara, Elena, and Diego Ferrando. "How to Model Uncertain Service Life and Durability of Components in Life Cycle Cost Analysis Applications? The Stochastic Approach to the Factor Method." Sustainability 10, no. 10 (2018): 3642. http://dx.doi.org/10.3390/su10103642.

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The durability of components is characterized by uncertainty, and, consequently, their estimated service life is critical for building project evaluation. Data on the durability of components used as life cycle cost analysis (LCCA) model input are able to influence model construction, model outputs, and residual value calculations. This implies dealing with uncertainty in cost estimates, according to the real estate market dynamics and the economic trends of the construction sector, and in service life estimates during the project time-horizon. This paper acknowledges the methodology presented

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Muhammad, Arsalan Ali Sajid, Hassan Muhammad, and Ayesha. "An overview of recent advancements in anti-aging medicines." World Journal of Advanced Research and Reviews 14, no. 1 (2022): 144–50. https://doi.org/10.5281/zenodo.7009076.

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The phenomenon of aging is most common to all living organisms and its definition is the loss or reduction of the ability to reproduce offspring and the slowly decrease in physical fitness. The current aging population is considered to be a major burden of the 21st century. Therefore, in order to slow the process of aging and maintain the health of the elderly, the discovery of new antiaging medicine remains a top priority. Several well-known researchers are working on this issue which is considered to be a multi-billions of dollars industry in future. Institutes like CRG with scientists like

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Gaire, Arjun Kumar, Yogendra Bahadur Gurung, and Tara Prasad Bhusal. "Stochastic Modeling of Age at Menarche for Nepalese Girls and Developing Menarchial Life Table." Population Review 63, no. 2 (2024): 146–61. https://doi.org/10.1353/prv.2024.a946252.

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Abstract: Menarche is one of the first and most significant milestones in a woman's fertility lifespan. It is a biological event in every girl's life; however, its timing is influenced by several biological and socioeconomic factors. Most studies on age at menarche have been mainly concerned with describing the statuses, differentials, and determinants. Skew distributions have been applied to fit the distributional pattern of age at menarche, and results are used to construct the menarchial life table. The objectives of this research are to explain the age at menarche of women by an efficient

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Abdulazeez, Sikiru Adeyinka. "BRANCHING PROCESS MODELLING: A TOOL FOR DECIPHERING COMPLEX REAL-WORLD PHENOMENA USING R PROGRAMMING." FUDMA JOURNAL OF SCIENCES 7, no. 3 (2023): 324–29. http://dx.doi.org/10.33003/fjs-2023-0703-1964.

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The reproduction of organisms such as human beings, cells or neutrons can be modeled via branching processes.The theory of branching processes offers suitable mathematical models to depict the chance-based progression of systems, where elements like cells, particles, or general individuals replicate and perish over a certain lifespan. These models are employed to illustrate stochastic systems like chain reactions, lineage continuation of surnames, elimination of pests, population growth, and gene spread. This study clearly showcases the likelihood of extinction, its timing, and the odds of com

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Patel, Nitin D., Dilip B. Patel, Dipak A. Patel, Nitin M. Patel, and J. R. Samriya. "Simulation of Jenkins Model-Based Ferrofluid Lubrication in Double-Layered Porous Hyperbolic Slider Bearings under Slip Conditions." Revista Review Index Journal of Multidisciplinary 4, no. 3 (2024): 41–55. https://doi.org/10.31305/rrijm2024.v04.n03.006.

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Bearings support moving parts and affect important mechanical properties like efficiency, friction, speed, and wear. To improve bearing performance and lifespan, it is vital to have contact surfaces that are tribologically optimised. An analysis of the impacts of slip velocity on the performance of a ferrofluid-lubricated, double-layered porous hyperbolic slider bearing is presented in this paper using a mathematical model. To find pressure distribution and important performance metrics like load-carrying capacity, friction, centre of pressure location, temperature rise, and stochastic surface

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van Dongen, Jenny, Fiona A. Hagenbeek, Matthew Suderman, et al. "DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan." Molecular Psychiatry 26, no. 6 (2021): 2148–62. http://dx.doi.org/10.1038/s41380-020-00987-x.

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AbstractDNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, stochastic, and environmental influences associated with aggression. Here, we report the first large meta-analysis of epigenome-wide association studies (EWAS) of aggressive behavior (N = 15,324 participants). In peripheral blood samples of 14,434 participants from 18 cohorts with mean ages ranging from 7 to 68 years, 13 methylation sites were significantly associated with aggression (alpha = 1.2 × 10−7; Bonferroni correction). In cord blood samples of 2425 children from five cohorts wit

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Stein, Aviva M., Melanie J. Young, John T. Darby, Philip J. Seddon, and Yolanda van Heezik. "Evidence for high inter-generational individual quality in yellow-eyed penguins." PeerJ 5 (February 28, 2017): e2935. http://dx.doi.org/10.7717/peerj.2935.

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Longitudinal studies focusing on lifetime reproductive success (LRS) have been used to measure individual breeding performance and identify commonalities among successful breeders. By extending the focus to subsequent generations we identify a proportion of high-quality individuals that contribute disproportionately to the population over multiple generations. We used 23 years of yellow-eyed penguin (Megadyptes antipodes) breeding data from one breeding area to identify the proportion of individual birds that raised successful breeders, which in turn raised offspring. We explored which life-hi

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Tao, Shiyong, Weirong Chen, Shuna Jiang, Xinyu Liu, and Jiaxi Yu. "INTELLIGENT HEALTH STATUS DETECTION METHOD FOR LOCOMOTIVE FUEL CELL BASED ON DATA-DRIVEN TECHNIQUES." DYNA 96, no. 6 (2021): 633–39. http://dx.doi.org/10.6036/10290.

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Main drawbacks of fuel cell systems, namely, high cost, poor reliability, and short lifespan, limit the large-scale commercial application of fuel cell systems. The health status detection of fuel cell systems for locomotives is of great significance to the safe and stable operation of locomotives. To identify the failure modes of the fuel cell system accurately and quickly, this study proposed an intelligent health status detection method for locomotive fuel cells based on data-driven techniques. In this study, the actual test data of a 150-kW fuel cell system for locomotives was analyzed. Th

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Pelosi, Dario, Federico Gallorini, Giacomo Alessandri, and Linda Barelli. "A Hybrid Energy Storage System Integrated with a Wave Energy Converter: Data-Driven Stochastic Power Management for Output Power Smoothing." Energies 17, no. 5 (2024): 1167. http://dx.doi.org/10.3390/en17051167.

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Beyond solar and wind energy, wave energy is gaining great interest due to its very high theoretical potential, although its stochastic nature causes intermittent and fluctuating power production. Energy storage system (ESS) integration to wave energy converter (WEC) plants represents a promising solution to mitigate this issue. To overcome the technological limits of the single storage devices, the hybridization of complementary ESSs represents an effective solution, extending the operating range over different timeframes. This paper analyzes the benefits of Li-ion battery–supercapacitor hybr

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Beaudouin, Rémy, Sandrine Micallef, and Céline Brochot. "A stochastic whole-body physiologically based pharmacokinetic model to assess the impact of inter-individual variability on tissue dosimetry over the human lifespan." Regulatory Toxicology and Pharmacology 57, no. 1 (2010): 103–16. http://dx.doi.org/10.1016/j.yrtph.2010.01.005.

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Agapitidou, Anastasia-Alkmini, Sofia Skroufouta, and Evangelos Baltas. "Methodology for the Development of Hybrid Renewable Energy Systems (HRES) with Pumped Storage and Hydrogen Production on Lemnos Island." Earth 3, no. 2 (2022): 537–56. http://dx.doi.org/10.3390/earth3020032.

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The non-interconnected islands of Greece can benefit from the comprehensive use of RES to avoid water droughts and ensure energy autonomy. The present paper analyzes an HRES with two possible operating scenarios. Both of them include a wind park of 27.5 MW capacity, an 1175 m3/day desalination plant, and a 490,000 m3/day water tank in Lemnos, Greece. Regarding the wind power, 70% is used in the HRES, while the rest is channeled directly to the grid. The main difference comes down to how the wind energy is stored, either in the form of hydraulic energy or in the form of hydrogen. The lifespan o

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