Academic literature on the topic 'Stoll, David'

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Journal articles on the topic "Stoll, David"

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Smith, Dorothy. "Rigoberta Menchú and David Stoll: Contending stories." International Journal of Qualitative Studies in Education 16, no. 3 (May 2003): 295–305. http://dx.doi.org/10.1080/0951839032000086718.

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Best, Eric. "Stoll, David. 2013. El Norte or Bust!" Society 50, no. 6 (October 3, 2013): 646–48. http://dx.doi.org/10.1007/s12115-013-9719-0.

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Watanabe, John M. ": Between Two Armies in the Ixil Towns of Guatemala . David Stoll." American Anthropologist 96, no. 3 (September 1994): 738–39. http://dx.doi.org/10.1525/aa.1994.96.3.02a00420.

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Apple, Michael W. "School Matters. Peter Mortimore , Pamela Sammons , Louise Stoll , David Lewis , Russell Ecob." Comparative Education Review 34, no. 2 (May 1990): 256–57. http://dx.doi.org/10.1086/446921.

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Drouin, Marc. "‘The realities of power’: David Stoll and the story of the 1982 Guatemalan genocide." Journal of Genocide Research 18, no. 2-3 (June 28, 2016): 305–22. http://dx.doi.org/10.1080/14623528.2016.1186956.

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EARLY, C. "A woman's skin By David Stoll. New Brunswick (NJ): Rutgers University Press, 1994. 243 pages. $dollar;14.95, soft cover." Journal of Nurse-Midwifery 42, no. 5 (September 1997): 448–49. http://dx.doi.org/10.1016/s0091-2182(97)90065-3.

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Raudenbush, Stephen W. "New Evidence in the Search for Effective Primary SchoolsSchool Matters. Peter Mortimore , Pamela Sammons , Louise Stoll , David Lewis , Russell Ecob." American Journal of Education 98, no. 2 (February 1990): 175–83. http://dx.doi.org/10.1086/443951.

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Gledhill, John. "Deromanticizing subalterns or recolonializing anthropology? Denial of indigenous agency and reproduction of northern hegemony in the work of david stoll." Identities 8, no. 1 (March 2001): 135–61. http://dx.doi.org/10.1080/1070289x.2001.9962687.

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Foxen, Patricia. "El Norte or Bust! How Migration Fever and Microcredit Produced a Financial Crash in a Latin American Town by David Stoll." American Anthropologist 117, no. 1 (February 22, 2015): 206–7. http://dx.doi.org/10.1111/aman.12220.

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Gros, Brother Jeffrey. "David Stoll, Is Latin America Turning Protestant? (Berkeley: University of California Press, 1990),.4 24 pp. $24.95. ISBN 0-520-06499-2." Pneuma 13, no. 1 (1991): 189–90. http://dx.doi.org/10.1163/157007491x00213.

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Dissertations / Theses on the topic "Stoll, David"

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Gorelashvili, Maximilian Georg [Verfasser], David [Gutachter] Stegner, Katrin [Gutachter] Heinze, Guido [Gutachter] Stoll, and Bernhard [Gutachter] Nieswandt. "Investigation of megakaryopoiesis and the acute phase of ischemic stroke by advanced fluorescence microscopy / Maximilian Georg Gorelashvili ; Gutachter: David Stegner, Katrin Heinze, Guido Stoll, Bernhard Nieswandt." Würzburg : Universität Würzburg, 2019. http://d-nb.info/1201278295/34.

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Batcheller, James Christopher. "Waking angels, a light unto the darkness, and a crescent still abides : the elegiac music of David R. Gillingham /." Full-text version available from OU Domain via ProQuest Digital Dissertations, 2000.

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Angwenyi, David [Verfasser], Sebastian [Akademischer Betreuer] Reich, and Claudia [Akademischer Betreuer] Stolle. "Time-continuous state and parameter estimation with application to hyperbolic SPDEs / David Angwenyi ; Sebastian Reich, Claudia Stolle." Potsdam : Universität Potsdam, 2019. http://d-nb.info/1219150053/34.

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Starr, Paul. "Another word for feeling : affect and still images in the work of Paul Auster, David Thomson and Atom Egoyan /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17860.pdf.

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Müller-Vahl, Hanns Friedrich [Verfasser], David [Akademischer Betreuer] Greenblatt, Christian Oliver [Akademischer Betreuer] Paschereit, Rimon [Akademischer Betreuer] Arieli, Rudibert [Akademischer Betreuer] King, and Eliezer [Akademischer Betreuer] Kit. "Wind turbine blade dynamic stall and its control / Hanns Friedrich Müller-Vahl. Gutachter: David Greenblatt ; Christian Oliver Paschereit ; Rimon Arieli ; Rudibert King ; Eliezer Kit. Betreuer: David Greenblatt ; Christian Oliver Paschereit." Berlin : Technische Universität Berlin, 2015. http://d-nb.info/1075547199/34.

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Wallis, Lucy. "An exploration of the work of David Bintley, a very 'English' choreographer, with particular reference to his use of English Morris dance in Still Life at the Penguin Café and the process of translating 'genuine' English Morris dance to a theatrical environment." Thesis, City, University of London, 2010. http://openaccess.city.ac.uk/17616/.

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The study explores the work of the English choreographer and Director of the Birmingham Royal Ballet, David Bintley. Particular reference is made to Bintley’s ballet Still Life at the Penguin Café (1988) and the extent to which he has drawn from English Cotswold Morris dance in the Humboldt’s Hog-nosed Skunk Flea section of the ballet. The comparison between Bintley’s selection of movements and their traditional Morris dance counterparts is based on findings from extensive fieldwork conducted with Morris dance teams and in particular the Ravensbourne Morris Men of Keston in Kent, as well as a study of Bintley’s creative practice. The research draws from ethnographic modes of study including participant observation, embodiment and notions of reflexivity. Following an analysis of the results from the creation and performance of a more authentically ‘Morris’ version of Bintley’s dance for eight female dancers, entitled Still Life at the Folk Café, the study offers a series of recommendations for the translation of English Morris into a theatrical setting. The thesis is divided into six chapters. The first explores the methods involved in the development of the analytical model for the study, including those of the Hungarian scholars György Martin and Erno Pesovár during their folk dance research in the Upper-Tisza region of Hungry, and the categorisation of the various aspects of Morris dance using Morris dancer Lionel Bacon's motif catalogue, A handbook of Morris dances. It also reviews the work of folk dance theorists such as John Forrest and Chris Bearman. The second chapter discusses the concept of Englishness to define the importance of the English ballet tradition as advocated from 1926 by the founder of the Royal Ballet, Dame Ninette De Valois. It looks at Bintley's influences, ideological inheritance, creative process and place as a protector of the English ballet tradition. Chapter three focuses on the fieldwork conducted with the Ravensbourne Morris Men, and compares Bintley’s movements in Humboldt’s Hog-nosed Skunk Flea dance with their counterparts from the Cotswold Morris tradition. Chapter four details the practice based element of the research and analyses the findings from a series of Morris dance workshops in which the eight female dancers representing the field of professional dance were introduced to the Morris dance form. It also investigates the results from the creation and performance of Still Life at the Folk Café. Chapter five discusses the benefits of conducting a workshop with the Ravensbourne Morris dance team and some of the dancers involved in the performance process. Finally chapter six explores the conclusions drawn from the research and explains how choreographers or dancers wishing to work with Morris dance should immerse themselves in the source language of its practitioners, and draw from aspects of the tradition in rehearsals and performances in order to extend their choreological and physical vocabulary and attain the stylistic and social qualities associated with the dance form. These aspects include working with live musical accompaniment, using the performance space informally to maintain close interaction with the audience and challenging the dancer’s personal response to their own movement style.
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Books on the topic "Stoll, David"

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Halliday, David. The perfect world of David Halliday. [South Dennis, Mass.]: Published by Steven Albahari, 21st, 2003.

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Who is Rigoberta Menchú? London: Verso, 2011.

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1966-, Sowiak Christine. That still place-- that place still: William MacDonnell, Landon Mackenzie, David McMillan, Eugene Ouchi. Calgary, AB: Nickle Arts Museum, 2003.

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David, Nash. Pyramids rise, spheres turn and cubes stand still: David Nash. London: Annely Juda Fine Art, 2004.

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Owens, Gwendolyn. Nature transcribed: The landscapes and still lifes of David Johnson (1827-1908) : an exhibition. Ithaca, N.Y: Herbert F. Johnson Museum of Art, 1988.

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C, Jacobson David. Does David still play before you?: Israeli poetry and the Bible = [Ha-ʻod Daṿid menagen lefanekha? : shirah Yiśreʼelit ṿeha-Tanakh]. Detroit: Wayne State University Press, 1997.

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Does David still play before you?: Israeli poetry and the Bible. Detroit: Wayne State University Press, 1997.

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Evans, David. The world of David Evans 1929-1988: Landscape, still life and fantasy. London: Redfern Gallery, 1988.

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David Busch's Nikon V1 guide to digital movie making and still photography. Boston, MA: Course Technology, 2012.

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David Busch's Nikon J1 guide to digital movie making and still photography. Boston, Mass: Course Technology, 2012.

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Book chapters on the topic "Stoll, David"

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Rymatzki, Christoph. "David Israel Dimpel (1678–1740) als Mitarbeiter Sprögels in Stolp und die Beziehungen zum Halleschen Pietismus nach Sprögels Tod." In Pietismus und Neuzeit Band 43 – 2017, 100–109. Göttingen: Vandenhoeck & Ruprecht, 2019. http://dx.doi.org/10.13109/9783666559150.100.

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"Merging school effectiveness and school improvement: practical examples: Louise Stoll, David Reynolds, Bert Creemers and David Hopkins." In Making Good Schools, 125–58. Routledge, 2005. http://dx.doi.org/10.4324/9780203975916-12.

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"Merging school effectiveness and school improvement: the knowledge bases: David ReynoldsLouise Stoll." In Making Good Schools, 107–24. Routledge, 2005. http://dx.doi.org/10.4324/9780203975916-11.

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Drouin, Marc. "‘The realities of power’: David Stoll and the story of the 1982 Guatemalan genocide." In Guatemala, the Question of Genocide, 169–86. Routledge, 2018. http://dx.doi.org/10.4324/9780203732328-10.

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Long, Kathryn T. "Leaving Ecuador." In God in the Rainforest, 258–72. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190608989.003.0017.

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This chapter describes opposition to the Summer Institute of Linguistics in Ecuador that had been building throughout the 1970s and that crested with the decision in May 1981 by President Jaime Roldós to issue Decree No. 1159, ending Ecuador’s contractual relationship with the Institute. The decree gave SIL a year to complete projects or turn them over to Ecuadorians. Although Roldós did not expel SIL, he curtailed the organization’s size and influence. He was responding to political supporters, to critical books by David Stoll and others, and to voices like that of Dayomæ’s son Sam Padilla Cænto, who characterized missionaries as the “worst enemy” of the Waorani. Some SIL staff, including Catherine Peeke and Rosi Jung, were allowed to stay to finish translation projects. Amid the upheaval, 1981 also marked the twenty-fifth anniversary of the five missionaries’ deaths, bringing with it scrutiny and unwanted publicity.
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Heilpern, John. "The Still Subversive Joe Orton." In How Good is David Mamet, Anyway?, 152–55. Routledge, 2013. http://dx.doi.org/10.4324/9781315023052-35.

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Dickens, Charles. "Chapter LIII Another Retrospect." In David Copperfield. Oxford University Press, 2008. http://dx.doi.org/10.1093/owc/9780199536290.003.0054.

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I Must pause yet once again. O, my child-wife, there is a figure in the moving crowd before my memory, quiet and still, saying in its innocent love and childish beauty, Stop to think of me—turn to look upon the little blossom, as...
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Curtis, Cathy. "Gloucester." In Alive Still, 137–54. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190908812.003.0010.

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In the summer of 1974, Nell found a cottage to buy in her beloved Gloucester. Named for her mother, Eudora Cottage would be her and Carolyn’s home from June to late autumn every year. Nell made detailed sketches for plants in the many gardens she envisioned. The house also had to be renovated to accommodate a wheelchair user’s needs. Exploring Cape Ann required the assistance of a household staff of three, one driving a vintage Cadillac. In her paintings of local vistas, Nell avoided postcard fidelity to nature, preferring to capture the effervescent quality of light on water and gardens rife with blooms. This chapter also takes a quick look at other notable artists, including Stuart Davis and Marsden Hartley, who drew and painted Gloucester landscapes. In 1975, when Nell’s poet friend Howard Griffin died in Austria, he left his property to Nell—a bequest that would broaden her horizons.
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Tobin, Claudia. "‘Past the gap where we cannot see’: Still Life and the ‘Numinous’ in British Painting of the 1920s–1930s." In Modernism and Still Life, 124–59. Edinburgh University Press, 2020. http://dx.doi.org/10.3366/edinburgh/9781474455138.003.0004.

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The relationship between still life, spiritual contemplation and the ‘numinous’ comes to the foreground in the work of British painters, Winifred Nicholson, Ben Nicholson, David Jones and Ivon Hitchens, in the context of the artists’ different commitments to the ‘spiritual’, from Christian Science to Catholic theology. This chapter proposes that still life - and in particular the ‘still life at a window motif’ - functions in their work as a mode through which to explore the relationship between the material and the immaterial, as well as to tease out fundamental aesthetic questions. It offers close readings of their still life and flower paintings of the 1920s and early 30s and of writings by contemporary collectors and by the artists, to make the case for the emergence of an ‘enchanted’ domesticity in their circle, which was intimately related to still life and its transformation of the everyday object world. It concludes with an excursion into Kettle’s Yard, Cambridge, the former home of Jim Ede, the collector and friend of the Nicholsons, to propose a reading of his domestic space as an extended still life.
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Field, Kendra Taira. "“No Such Thing as Stand Still”." In Growing Up with the Country. Yale University Press, 2018. http://dx.doi.org/10.12987/yale/9780300180527.003.0005.

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Chapter 4 recovers the origins of the little-known 1913–15 Chief Sam back-to-Africa movement and the lifelong migrants who created it. African-American access to Indian land ended abruptly after 1907 with the advent of Oklahoma statehood, Jim Crow segregation, and oil speculation. These migrants and many of their black and Indian counterparts lost their land and the associated mineral rights to white settlers and oil speculators through a combination of legal and extralegal exploitation. Thousands, including Coleman and Davis, joined Chief Alfred Sam’s 1914 “back-to-Africa” movement in hopes of claiming lasting freedom once and for all on the Gold Coast. This chapter employs the stories of Elic Davis and Monroe Coleman to show that this movement was not only prelude to Garveyism and the Great Migration, but capstone to “a century of negro migration.”
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Conference papers on the topic "Stoll, David"

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Hutcheson, Joshua D., and W. David Merryman. "Serotonin Antagonists Prevent Cytokine and Mechanical Activation of Aortic Valve Interstitial Cells." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19389.

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Degenerative aortic valve disease (DAVD) is the most common heart valve pathology and is especially prevalent in the elderly population. Studies have shown that stenosis, the most severe form of DAVD, increases in prevalence from 0.7% in people between 18 and 44 years of age to over 13% of people over 75 years of age. Furthermore, early symptoms of DAVD have been detected in 29% of patients over 65 years of age. These symptoms are associated with a 50% increase in cardiovascular related morbidity and a similar increase in the risk of myocardial infarction [1]. Currently, aortic valve (AV) replacement surgery is the only method available to correct DAVD, and while these procedures have become less invasive, replacement valves are still rather expensive and do not function as well as native valves. Therefore, the development of a therapeutic that could prevent DAVD would greatly benefit many patients.
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George, Jeff, and David Massingham. "Moving Towards a Sustainable UK in an Environment of Austerity: Can We Wait Until the Midnight Hour?" In 19th Annual North American Waste-to-Energy Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/nawtec19-5410.

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The UK coalition government, elected in May 2010, has set out its stall to be, in the words of Prime Minister, David Cameron, “the greenest government ever”. To that end it has embarked on an ambitious programme of policy initiatives to address climate change and the wider sustainability agenda. These include: • Initiating a fundamental review of waste policy with a view to adopting a zero waste to landfill and increasing Energy from Waste (EfW) as a solution for residual wastes; • Leading calls within the European Union for an increase in pan-Europe greenhouse gas reduction and renewable energy targets for 2020, that, if adopted would have a profound and immediate impact on domestic targets; and • An electricity market reform package that will see the introduction of a floor price for carbon (in effect, a carbon tax) and new financial support mechanisms for the development of renewable energy.
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Obikawa, Toshiyuki, M. T. Postek, David Dornfeld, Richard Liu, Ranga Komanduri, Yuebin Guo, Jing Shi, et al. "MSEC 2009 State-of-Art Paper: Micro/Nano-Technology Applications for Manufacturing Systems and Processes." In ASME 2009 International Manufacturing Science and Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/msec2009-84330.

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Micro/nano-technology has made tremendous impact in all science and engineering fields in last decades. While review papers on meso/micro/nano manufacturing systems and processes have been published recently, there still lacks a review on how micro/nano technology has been applied to advance fundamental understanding and to enhance practice for manufacturing systems and processes. This paper is not concerned about the advances in meso/micro/nano manufacturing processes and systems themselves, but focuses on their impact on manufacturing applications. This paper presents the state-of-art of the advances on various aspects of how micro/nano technology impacts macro manufacturing systems/processes. Due to the time and space limit, this paper particularly reviews the topics as follows, 1. Micro/nano sensor applications in manufacturing (by Toshiyuki Obikawa and Xiaochun Li), 2. Micro/nano metrology for manufacturing applications (by M.T Postek), 3. Design and manufacturing of micro patterned arrays over macro-scale areas (by David Dornfeld), 4. Functionlized nanodiamonds and applications (by Jack Zhou), 5. Computational simulations at nanoscale for machining (By Ranga Komanduri), 6. Machining surface integrity and multiscale simulation (by C. Richard Liu, Jing Shi, Yuebin Guo, and Xiaoping Yang), and 7. Simulation for forming of parts with micro features (by Jian Cao).
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Najimudinova, Seyil. "Content Analyses on Mission Statements of the Commercial Banks in Kyrgyzstan." In International Conference on Eurasian Economies. Eurasian Economists Association, 2017. http://dx.doi.org/10.36880/c08.01835.

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The concept of mission is still popular both in academic environment and business practices. Mission statements have been accepted as an important part of the strategic management process for organizations of all types; be it public sector, not-for-profit, private, for profit, a multinational or a SME. This paper aims to study the content of mission statements of Top10 commercial banks in Kyrgyzstan. The main objective of this study is to identify whether the mission statements of commercial banks contain components suggested Pierce and David (1987) and Bart and Tabone (1999). Data was based on content analysis of the mission statements and other related statements found on commercial banks’ web sites. Another secondary data on general profile of commercial banks are obtained from their web-sites and other open to public resources. The results show all (11) numbers of components are not incorporated in the mission statements of commercial banks totally. According to obtained data it was done Top 3 rating of commercial banks according to their mission statements. The level of popularity of mission statement components displays the following: products or services, geographic location, statement of purpose and customers are the most of frequent occurrence components. Components like concern for public image, concern for growth and profit, and philosophy are less popular mission components. In the future this study can throw fresh light on researches on other industries and to make relationship between good mission statements and the performance of commercial banks.
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Brown, Robert, Kerri-Ann Evely, Graham Small, and Scott MacKinnon. "Using a Dacon Scoop to Recover a Loaded Liferaft at Sea." In ASME 2013 32nd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/omae2013-11020.

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Service and supply vessels that perform standby duties in the offshore sector are equipped with a variety of resources with which to perform rescue at sea. For light to moderate sea conditions, techniques currently understood and practiced tend to involve using a fast rescue craft (FRC) to rescue survivors and subsequently transfer them to a safe haven (often a standby vessel). Rescuing evacuees in higher, more challenging sea states, however, is difficult given that it can be unsafe to launch and recover FRCs in such conditions. For these cases, many standby vessels in Eastern Canada and the North Sea are equipped with a device called a Dacon Scoop. The Dacon Scoop is a 6 to 8m semi-rigid net that is deployed directly from the side of the standby vessel and designed to rescue people directly from the water. While not a conventional use, it has been suggested that the scoop could also be used to recover small rescue craft (life rafts, lifeboats and fast rescue craft) at sea. Although life rafts provide occupants with some protection from the elements, there are still issues that can make it less than desirable to remain inside for extended periods of time if an effective means of system recovery is available. This paper presents the findings of research carried-out to determine if it is safe to use a Dacon Scoop to recover a loaded liferaft. The research trials made use of a loaded inflatable 25 person davit launched life raft and two different standby vessels 75m in length. A total of 34 tests were carried out over three days in significant wave heights up to 3.7m. Recommendations are given in the context of a human factor assessment related to the procedures, equipment and field trials experiences.
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Kar, Apurba, and Sandip Patil. "A Modified Structural Arrangement of Rigs for Safe Launching of Life Boats and Berthing of OSVs." In ASME 2011 30th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2011. http://dx.doi.org/10.1115/omae2011-49713.

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It has long been experienced that Launching of lifeboat from rigs and Positioning of offshore supply vessel (OSV) near rigs are very critical and vulnerable operations as regards to the safety. In present days, sophisticated & expensive Dynamic Positioning (DP) Systems are used in order to avoid the collision of OSVs with rigs. However, it is observed that despite the provision of such sophisticated means, accidents are still occurring. Loss of control during positioning of OSVs can lead to severe accident (e.g. collision of OSV Samudra Shakti with Mumbai High North (MHN) platform in 2005). To avoid such accidents, considerable gap needs to be maintained between the OSV and the rig position. Also launching of lifeboat is known to be another safety critical operation. Particularly in rough weather, the landing of lifeboat requires to be at least 20 to 30m away from the platform. This is essential for preventing the lifeboat to drift under the platform and colliding with the structure & piping system there at. Lifeboat launching by davit lowering or freefall have got their own traditional problems as widely known in shipping industry. These are described in the paper “Safety of Lifeboat launching - Some Possible Improvements {P19J_AB27}” presented at Design for Safety Conference-2010 held in Italy. Considering both the issues as described above, it is evident that maintaining adequate distance from the rig is a crucial factor for improving safety of Life Boat launching and positioning of OSVs alongside the rigs. In order to achieve this, an additional structural part of the rig is proposed in this paper. This new structural entity is to be in the form of an inclined truss which will act as launching skid for the lifeboat. This arrangement will provide a guided slipway to enable landing of lifeboat at a considerable distance from the rig. Also this structure will be configured suitably to enable berthing & mooring of supply vessels alongside the rig. In this arrangement the DP system will be required for a short time only, at the initial stage of placing the vessel. After having the vessel positioned, she can be moored with the new proposed truss structure. Thus the dependency of DP System will reduce significantly to avoid collisions. So the authors believe that the proposed arrangement will improve the safety of offshore operation in a significant manner.
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Carlsen, E., and H. Prydz. "ROLE OF BIOLOGICAL RESPONSE MODIFIERSIN THE REGULATION OF THROMBOPLASTIN SYNTHESIS IN MONOCYTES AND ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643736.

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A rabbit polyclonal antibody which was monospecific for thromboplastin (TP) apoprotein from human brain according to a number of criteria was used to screen two human placenta cDNA libraries in the expression vector Agtll, one randomly primed and one oligo-dT primed, by the method of Young and Davis. 23 positive clones expressing TP related antigen were isolated and plaque purified. DNA from the different clones was isolated and the TPcDNA inserts released by EcoRl digestion. The inserts could be classified into11 size classes ranging from approx. 300-1100 base pairs.The largest insert (1100 bp) was subcloned intothe plasmid vector pGEM-1. When the nick-translated plasmid (pTP4-l) was used as a probe to screen the phage clones by slot blot hybridization all the 23clones hybridized to the 1100 bp insert. A XgtllTP4 lysogen expressed B-galactosidase- TP4 fusion peptide upon IPTG induction as shown by immunobinging studied using two different antibodies to TP apoprotein: the rabbit antibody originally used to screen the libraries and an antibody raised in goat against human brain TP purified by affinity chromatography on a Factor Vll-antiVII-agarose column.Cytokines mediate many of the cellular interactions in the inflammatory and immune response systems and have a variety of actions. We have investigated the effect of rIL-1a/$,rIL-2, rlFNa/y and rTNFa on thromboplastin synthesis (TPL) in monocytes (M) and human umbilical vein endothelial cells (HUVEC). Recombinant IL- 1a and IL-16 both induced a dose dependent increase in TPL activity of monocyte (8-fold) and HUVEC cultures (15-fold) at 6h. The increase levelled off at interleukinconcentrations of 50-100u/ml. Recombinant IL-2 at 50u/ml induced a 5-fold rise in monocytes TPL. The effect of rIL-2 on HUVEC TPL synthesis at 6 h was smaller than on monocytes but still clearly significant at dose dependent. Recombinant IFN-Y (10 -10 u/ml) increased.TPL activity in HUVEC at 6h and 16 h in adose dependent manner, whereas no effect of rIFN-Y and IFN-a (1-10 u/ml) on M TPL was seen. When LPS (5pg/ml) was used to induce TPL synthesis, additional stimulation with rIFN-Y further enhanced HUVEC TPL activity, but decreased M TPL activity. Recombinant IFNa also decreased LPS induced TPL synthesis in M andhad no effect on HUVEC TPL. Recombinant TNFa (0.3x104u/ml) increased HUVEC TPL 7-fold at 6h. There wasno effect on M TPL synthesis. No endotoxin was detected in any of these preparations. CONCLUSIONS: Some biological response modifiers induced thromboplastin synthesis in monocytes (IL-ia, IL-13, IL-2) and in human umbilical vein endothelial cells (IL-ia, IL-18, IL-2, TNFa and IFNY). Some had no direct effect on TPL synthesis but inhibited the response to monocytes to other thromboplastin-inducing agents like LPS (IFNa and IFNY).
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