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Journal articles on the topic 'Storage lipid degradation'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Van Bilsen, Danielle G. J. L., Tineke van Roekel, and Folkert A. Hoekstra. "Declining viability and lipid degradation during pollen storage." Sexual Plant Reproduction 7, no. 5 (1994): 303–10. http://dx.doi.org/10.1007/bf00227714.

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2

Müllner, Heidemarie, and Günther Daum. "Dynamics of neutral lipid storage in yeast." Acta Biochimica Polonica 51, no. 2 (2004): 323–47. http://dx.doi.org/10.18388/abp.2004_3574.

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Since energy storage is a basic metabolic process, the synthesis of neutral lipids occurs in all kingdoms of life. The yeast, Saccharomyces cerevisiae, widely accepted as a model eukaryotic cell, contains two classes of neutral lipids, namely steryl esters and triacylglycerols. Triacylglycerols are synthesized through two pathways governed by the acyl-CoA diacylglycerol acyltransferase Dga1p and the phospholipid diacylglycerol acyltransferase Lro1p, respectively. Steryl esters are formed by the two steryl ester synthases Are1p and Are2p, two enzymes with overlapping function which also catalyz

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Anheuser, Susi, Bernadette Breiden, and Konrad Sandhoff. "Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles." Journal of Lipid Research 60, no. 6 (2019): 1099–111. http://dx.doi.org/10.1194/jlr.m092551.

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The catabolism of ganglioside GM2 is dependent on three gene products. Mutations in any of these genes result in a different type of GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease, and the B1 and AB variants of GM2 gangliosidosis), with GM2 as the major lysosomal storage compound. GM2 is also a secondary storage compound in lysosomal storage diseases such as Niemann-Pick disease types A–C, with primary storage of SM in type A and cholesterol in types B and C, respectively. The reconstitution of GM2 catabolism at liposomal surfaces carrying GM2 revealed that incorporating lipids into t

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Masclaux-Daubresse, Céline, Sabine d’Andrea, Isabelle Bouchez, and Jean-Luc Cacas. "Reserve lipids and plant autophagy." Journal of Experimental Botany 71, no. 10 (2020): 2854–61. http://dx.doi.org/10.1093/jxb/eraa082.

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Abstract Autophagy is a universal mechanism that facilitates the degradation of unwanted cytoplasmic components in eukaryotic cells. In this review, we highlight recent developments in the investigation of the role of autophagy in lipid homeostasis in plants by comparison with algae, yeast, and animals. We consider the storage compartments that form the sources of lipids in plants, and the roles that autophagy plays in the synthesis of triacylglycerols and in the formation and maintenance of lipid droplets. We also consider the relationship between lipids and the biogenesis of autophagosomes,

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DeMaggio, A. E., and D. A. Stetler. "Mobilisation of storage reserves during fern spore germination." Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences 86 (1985): 195–202. http://dx.doi.org/10.1017/s0269727000008137.

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SynopsisWe have studied morphological and biochemical aspects of storage reserves and their degradation in fern spores during the germination process. The results presented here are concerned with the fate of lipid, protein and phytic acid. Depletion of lipid reserves and breakdown of lipid bodies was directly correlated with increased activity of glyoxylate cycle enzymes during early stages of germination. Degradation of protein reserves coincided with the depletion of salt soluble proteins (globulins) from the spores and was related to the time when high activity of aminopeptidase and carbox

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Meex, Ruth C. R., Patrick Schrauwen, and Matthijs K. C. Hesselink. "Modulation of myocellular fat stores: lipid droplet dynamics in health and disease." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 297, no. 4 (2009): R913—R924. http://dx.doi.org/10.1152/ajpregu.91053.2008.

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Storage of fatty acids as triacylglycerol (TAG) occurs in almost all mammalian tissues. Whereas adipose tissue is by far the largest storage site of fatty acids as TAG, subcellular TAG-containing structures—referred to as lipid droplets (LD)—are also present in other tissues. Until recently, LD were considered inert storage sites of energy dense fats. Nowadays, however, LD are increasingly considered dynamic functional organelles involved in many intracellular processes like lipid metabolism, vesicle trafficking, and cell signaling. Next to TAG, LD also contain other neutral lipids such as dia

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SALIH, A. M., J. F. PRICE, D. M. SMITH, and L. E. DAWSON. "Lipid Degradation in Turkey Breast Meat During Cooking and Storage." Poultry Science 68, no. 6 (1989): 754–61. http://dx.doi.org/10.3382/ps.0680754.

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8

Sandhoff, Konrad. "Metabolic and cellular bases of sphingolipidoses." Biochemical Society Transactions 41, no. 6 (2013): 1562–68. http://dx.doi.org/10.1042/bst20130083.

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Lysosomes are cellular stomachs. They degrade macromolecules and release their components as nutrients into the cytosol. Digestion of sphingolipids and other membrane lipids occurs at luminal intraendosomal vesicles and IMs (intraendosomal membranes). Sphingolipid and membrane digestion needs catabolic hydrolases with the help of lipid-binding proteins [SAPs (sphingolipid activator proteins)] and anionic lipids such as BMP [bis(monoacylglycero)phosphate]. Inherited defects of hydrolases or SAPs or uptake of cationic amphiphilic drugs cause lipid accumulation, eventually leading to death, espec

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Cisa-Wieczorek, Sabina, and María Isabel Hernández-Alvarez. "Deregulation of Lipid Homeostasis: A Fa(c)t in the Development of Metabolic Diseases." Cells 9, no. 12 (2020): 2605. http://dx.doi.org/10.3390/cells9122605.

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Lipids are important molecules for human health. The quantity and quality of fats consumed in the diet have important effects on the modulation of both the natural biosynthesis and degradation of lipids. There is an important number of lipid-failed associated metabolic diseases and an increasing number of studies suggesting that certain types of lipids might be beneficial to the treatment of many metabolic diseases. The aim of the present work is to expose an overview of de novo biosynthesis, storage, and degradation of lipids in mammalian cells, as well as, to review the published data descri

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Hyang Lan Eum, Dae Keun Hwang, and Seung Koo Lee. "Nitric Oxide Reduced Chlorophyll Degradation in Broccoli (Brassica oleracea L. var. italica) Florets During Senescence." Food Science and Technology International 15, no. 3 (2009): 223–28. http://dx.doi.org/10.1177/1082013208339706.

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Nitric oxide (NO) was applied to broccoli (Brassica oleracea L. var. italica) florets and analyzed its effect on chlorophyll degradation during postharvest senescence. Florets were treated with 1000 µL/L of NO for 5 h and placed in darkness at 20°C. During storage, the NO treatment delayed yellowing and retarded the onset of chlorophyll degradation. The activity of lipoxygenase was not related to the development of yellowing during storage. However, the accumulation of malondialdehyde, which could be used as an index of lipid peroxidation, was higher in the control than observed in the NO trea

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Yamauchi, Naoki, and Alley E. Watada. "Regulated Chlorophyll Degradation in Spinach Leaves during Storage." Journal of the American Society for Horticultural Science 116, no. 1 (1991): 58–62. http://dx.doi.org/10.21273/jashs.116.1.58.

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Degradation of chlorophyll in spinach (Spinacia olearacea L. cv. Hybrid 612) appeared to be regulated through the peroxidase-hydrogen peroxide pathway, which opens the porphyrin ring, thus resulting in a colorless compound. This conclusion was arrived at from the analysis of chlorophylls (Chls) and their metabolizes by HPLC and of enzyme activities catalyzing the degradative reactions. Chls decreased at 25C but not at 1C. The chlorophyll oxidase pathway was not active, as noted by the lack of accumulation of a reaction product named Chl a-1. Lipid peroxidation increased with storage, but the p

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Wang, Qingling, Guofeng Jin, Ning Wang, Yongguo Jin, Meihu Ma, and Xin Guo. "Lipolysis and oxidation of lipids during egg storage at different temperatures." Czech Journal of Food Sciences 35, No. 3 (2017): 229–35. http://dx.doi.org/10.17221/174/2016-cjfs.

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The aim of this study was to investigate lipolysis and lipid oxidation of stored eggs at different temperatures (4 and 22°C) by evaluating the changes in physicochemical index, lipid profiles, enzymatic activity, and oxidative index. The results showed that the changes in physicochemical index were more significant at 22°C than at 4°C. Weight loss, moisture content, and pH of egg yolk increased significantly (P &lt; 0.05), whereas the yolk index decreased during storage. However, there was no significant difference in lipid profiles between 4 and 22°C storage temperature. The lipid composi

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Breiden, Bernadette, and Konrad Sandhoff. "Lysosomal Glycosphingolipid Storage Diseases." Annual Review of Biochemistry 88, no. 1 (2019): 461–85. http://dx.doi.org/10.1146/annurev-biochem-013118-111518.

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Glycosphingolipids are cell-type-specific components of the outer leaflet of mammalian plasma membranes. Gangliosides, sialic acid–containing glycosphingolipids, are especially enriched on neuronal surfaces. As amphi-philic molecules, they comprise a hydrophilic oligosaccharide chain attached to a hydrophobic membrane anchor, ceramide. Whereas glycosphingolipid formation is catalyzed by membrane-bound enzymes along the secretory pathway, degradation takes place at the surface of intralysosomal vesicles of late endosomes and lysosomes catalyzed in a stepwise fashion by soluble hydrolases and as

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14

Breiden, Bernadette, and Konrad Sandhoff. "Emerging mechanisms of drug-induced phospholipidosis." Biological Chemistry 401, no. 1 (2019): 31–46. http://dx.doi.org/10.1515/hsz-2019-0270.

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Abstract Drug-induced phospholipidosis is a lysosomal storage disorder characterized by excessive accumulation of phospholipids. Its cellular mechanism is still not well understood, but it is known that cationic amphiphilic drugs can induce it. These drugs have a hydrophilic amine head group that can be protonated in the endolysosomal compartment. As cationic amphiphiles, they are trapped in lysosomes, where they interfere with negatively charged intralysosomal vesicles, the major platforms of cellular sphingolipid degradation. Metabolic principles observed in sphingolipid and phospholipid cat

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15

Alvebratt, Caroline, Tahnee J. Dening, Michelle Åhlén, et al. "In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier." Pharmaceutics 12, no. 5 (2020): 426. http://dx.doi.org/10.3390/pharmaceutics12050426.

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Lipid-based formulations can circumvent the low aqueous solubility of problematic drug compounds and increase their oral absorption. As these formulations are often physically unstable and costly to manufacture, solidification has been suggested as a way to minimize these issues. This study evaluated the physicochemical stability and in vitro performance of lipid-loaded mesoporous magnesium carbonate (MMC) particles with an average pore size of 20 nm. A medium chain lipid was loaded onto the MMC carrier via physical adsorption. A modified in vitro lipolysis setup was then used to study lipid r

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16

Sathiyamoorthy, P., and S. Nakamura. "FREE-RADICAL-INDUCED LIPID PEROXIDATION IN SEEDS." Israel Journal of Plant Sciences 43, no. 4 (1995): 295–302. http://dx.doi.org/10.1080/07929978.1995.10676616.

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From the practical standpoint, it is desirable to prolong the shelf life of seeds not only under optimum conditions of storage but also under suboptimal conditions. Production of radicals and their intermediates during storage of low or high lipid-containing seeds, and their relationship to seed aging is poorly understood. Reactions involving free radicals are an inherent feature of seed deterioration. Evidence suggests that degradation of lipids in deteriorating seeds, releasing free fatty acids, initiates oxidative deterioration by providing substrate for lipoxygenase. Membranes are primary

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17

Santana Neto, Deocleciano C. de, Ângela M. T. M. Cordeiro, Bruno R. L. A. Meireles, et al. "Inhibition of Protein and Lipid Oxidation in Ready-to-Eat Chicken Patties by a Spondias mombin L. Bagasse Phenolic-Rich Extract." Foods 10, no. 6 (2021): 1338. http://dx.doi.org/10.3390/foods10061338.

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This study evaluated the impact of yellow mombin (Spondias mombin L.) bagasse extract (YMBE) on the color degradation, protein and lipid oxidation in ready-to-eat chicken patties during 15 days of refrigerated storage. Two formulations of chicken patties were developed: chicken patties control - PCON (without the antioxidant extract) and chicken patties with yellow mombin extract - PYME (with the antioxidant extract). The extract was effective in maintaining red color and inhibiting myoglobin degradation in the evaluated samples. The generation of lipid oxidation compounds during storage of th

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18

Molina, Marion d. C., and Thomas J. Anchordoquy. "Degradation of lyophilized lipid/DNA complexes during storage: The role of lipid and reactive oxygen species." Biochimica et Biophysica Acta (BBA) - Biomembranes 1778, no. 10 (2008): 2119–26. http://dx.doi.org/10.1016/j.bbamem.2008.04.003.

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Arrese, Estela L., Fredy Z. Saudale, and Jose L. Soulages. "Lipid Droplets as Signaling Platforms Linking Metabolic and Cellular Functions." Lipid Insights 7 (January 2014): LPI.S11128. http://dx.doi.org/10.4137/lpi.s11128.

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The main cells of the adipose tissue of animals, adipocytes, are characterized by the presence of large cytosolic lipid droplets (LDs) that store triglyceride (TG) and cholesterol. However, most cells have LDs and the ability to store lipids. LDs have a well-known central role in storage and provision of fatty acids and cholesterol. However, the complexity of the regulation of lipid metabolism on the surface of the LDs is still a matter of intense study. Beyond this role, a number of recent studies have suggested that LDs have major functions in other cellular processes, such as protein storag

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20

Willemot, C., N. Fillion-Delorme, and D. F. Wood. "Effect of Nitrite on Lipid Degradation During Storage of Cooked Pork Meat." Canadian Institute of Food Science and Technology Journal 20, no. 2 (1987): 70–74. http://dx.doi.org/10.1016/s0315-5463(87)71092-x.

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21

Popelka, Peter, Monika Šuleková, Pavlína Jevinová, et al. "Influence of smoking and packaging methods on physicochemical and microbiological quality of smoked mackerel (Scomber scombrus)." Acta Veterinaria Brno 90, no. 1 (2021): 117–24. http://dx.doi.org/10.2754/avb202190010117.

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Flesh and fatty acid compositions, total volatile basic nitrogen (TVB-N), lipid oxidation and aerobic plate count, Enterobacteriaceae, psychrotrophic bacteria were determined in raw and smoked mackerel during cold storage (three groups differing in way of packaging; unpacked (UP), vacuum packaging (VP) and modified atmosphere (MAP) at 7, 14, 21, 28, 35, and 42 days. The protein, fat content and n-3 polyunsaturated fatty acids increased after smoking. The pH value and TVB-N were significantly higher in unpacked mackerel. Initial malondialdehyde concentration in raw mackerel was lowered after sm

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22

Ramella, Alberto, Gabriella Roda, Radmila Pavlovic, et al. "Impact of Lipid Sources on Quality Traits of Medical Cannabis-Based Oil Preparations." Molecules 25, no. 13 (2020): 2986. http://dx.doi.org/10.3390/molecules25132986.

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The feasibility of the use of two lipid sources and their impact on the cannabinoid profile, terpene fingerprint, and degradation products in medical cannabis oil preparations during 3 months of refrigerated storage time were investigated. LCHRMS-Orbitrap® and HS-SPME coupled to GC-MS for the investigation of targeted and untargeted cannabinoids, terpenes, and lipid degradation products in Bedrocan® and Bediol® macerated oils were used as analytical approaches. As regards the cannabinoid trend during 90 days of storage, there were no differences between PhEur-grade olive oil (OOPH) and medium-

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Sakiroh, Sakiroh, Taryono Taryono, and Setyastuti Purwanti. "Dynamics of Storage Materials in Cotyledon During Cocoa Seed Germination." Ilmu Pertanian (Agricultural Science) 3, no. 1 (2019): 12. http://dx.doi.org/10.22146/ipas.34594.

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Degradation of carbohydrate, protein and lipid food reserves occurs in the seed germination process to produce energy for germination and further growing. This study aimed to determine dynamics the content of protein, carbohydrates, and lipid in cotyledon of seed clon i.e. Sca 6, RCC 70, RCC 71 and KKM 22 during germination. The experiment used completely randomized design consisted of four replications with 4 treatments. In each cocoa germination phases i.e. before germination, phase II (bend/curved phase), cotyledon emergence, leaves emergence and fall of cotyledon from the sprouts. This obs

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Demirbaş, Ayse. "Red Cabbage Extracts as Inhibitors of Lipid Oxidation in Fresh Minced Tilapia (Nile perch) During Refrigerated Storage." Turkish Journal of Agriculture - Food Science and Technology 8, no. 1 (2020): 81. http://dx.doi.org/10.24925/turjaf.v8i1.81-88.2741.

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This study was performed to evaluate effects of red cabbage extract as a preservative against lipid oxidation for quality and shelf life of minced Tilapia (Nile perch) during refrigerated storage at 4  1°C. Untreated and treated samples were examined from day 0 to 10 during refrigerated storage using thiobarbituric acid reactive substances (TBARS) assay, peroxide value (PV), pH and color analysis. Samples treated with red cabbage extract showed less degradation due to lipid oxidation compared to untreated samples. Lipid peroxide values on treated samples showed benefits through day-6. This wo

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Yulianita, Rini, Iyan Sopyan, and Muchtaridi Muchtaridi. "FORCED DEGRADATION STUDY OF STATINS: A REVIEW." International Journal of Applied Pharmaceutics 10, no. 6 (2018): 38. http://dx.doi.org/10.22159/ijap.2018v10i6.29086.

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Forced degradation study is the degradation of new drug substances and drug products in more severe conditions than accelerated conditions. Forced degradation study were conducted to demonstrate the specificity of stability-indicating methods, providing insight into degradation pathways and drug degradation products, assisting in the elucidation of degradation product structures, identifying degradation products that could be spontaneously generated during storage and use of drugs and to facilitate improvement in manufacturing process and formulation corresponding with accelerated stability st

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Chen, Hong, Yufei Huang, Ping Yang, et al. "Lipophagy contributes to long-term storage of spermatozoa in the epididymis of the Chinese soft-shelled turtle Pelodiscus sinensis." Reproduction, Fertility and Development 31, no. 4 (2019): 774. http://dx.doi.org/10.1071/rd18307.

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Spermatozoa are known to be stored in the epididymis of the Chinese soft-shelled turtle Pelodiscus sinensis for long periods after spermiation from the testes, but the molecular mechanisms underlying this storage are largely unknown. In this study, epididymal spermatozoa were investigated to determine the potential molecular mechanism for long-term sperm storage in P. sinensis. Transmission electron microscopy (TEM) and Oil red O staining indicated that unusually large cytoplasmic droplets containing lipid droplets (LDs) were attached to the epididymal spermatozoa. However, the content of LDs

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Poxleitner, Marianne, Sally W. Rogers, A. Lacey Samuels, John Browse, and John C. Rogers. "A role for caleosin in degradation of oil-body storage lipid during seed germination." Plant Journal 47, no. 6 (2006): 917–33. http://dx.doi.org/10.1111/j.1365-313x.2006.02845.x.

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Moellering, Eric R., and Christoph Benning. "RNA Interference Silencing of a Major Lipid Droplet Protein Affects Lipid Droplet Size in Chlamydomonas reinhardtii." Eukaryotic Cell 9, no. 1 (2009): 97–106. http://dx.doi.org/10.1128/ec.00203-09.

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ABSTRACT Eukaryotic cells store oils in the chemical form of triacylglycerols in distinct organelles, often called lipid droplets. These dynamic storage compartments have been intensely studied in the context of human health and also in plants as a source of vegetable oils for human consumption and for chemical or biofuel feedstocks. Many microalgae accumulate oils, particularly under conditions limiting to growth, and thus have gained renewed attention as a potentially sustainable feedstock for biofuel production. However, little is currently known at the cellular or molecular levels with reg

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Liu, Juan, Qingxin Li, Junjia Chen, and Yueming Jiang. "Revealing Further Insights on Chilling Injury of Postharvest Bananas by Untargeted Lipidomics." Foods 9, no. 7 (2020): 894. http://dx.doi.org/10.3390/foods9070894.

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Chilling injury is especially prominent in postharvest bananas stored at low temperature below 13 °C. To elucidate better the relationship between cell membrane lipids and chilling injury, an untargeted lipidomics approach using ultra-performance liquid chromatography–mass spectrometry was conducted. Banana fruit were stored at 6 °C for 0 (control) and 4 days and then sampled for lipid analysis. After 4 days of storage, banana peel exhibited a marked chilling injury symptom. Furthermore, 45 lipid compounds, including glycerophospholipids, saccharolipids, and glycerolipids, were identified with

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Voisin, Pierre, Marianne Bernard, Thierry Bergès, and Matthieu Régnacq. "Amino acid starvation inhibits autophagy in lipid droplet-deficient cells through mitochondrial dysfunction." Biochemical Journal 477, no. 18 (2020): 3613–23. http://dx.doi.org/10.1042/bcj20200551.

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Lipid droplets are ubiquitous organelles in eukaryotes that act as storage sites for neutral lipids. Under normal growth conditions, they are not required in the yeast Saccharomyces cerevisiae. However, recent works have shown that lipid droplets are required for autophagy to proceed in response to nitrogen starvation and that they play an essential role in maintaining ER homeostasis. Autophagy is a major catabolic pathway that helps degradation and recycling of potentially harmful proteins and organelles. It can be pharmacologically induced by rapamycin even in the absence of lipid droplets.

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Agarwal, Deepa, Lim Mui, Emma Aldridge, James McKinney, Louise Hewson та Ian Denis Fisk. "The progression of lipid oxidation, β-carotenes degradation and sensory perception of batch-fried sliced sweet potato crisps during storage". Food & Function 12, № 10 (2021): 4535–43. http://dx.doi.org/10.1039/d0fo03100c.

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Tappi, Silvia, Ana Cristina De Aguiar Saldanha Pinheiro, Dario Mercatante, et al. "Quality Changes during Frozen Storage of Mechanical-Separated Flesh Obtained from an Underutilized Crustacean." Foods 9, no. 10 (2020): 1485. http://dx.doi.org/10.3390/foods9101485.

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Despite their high nutritional value, high quantities of fish caught in the Adriatic Sea are underused or discarded for their insignificant economic value. Mechanical separation of flesh represents an opportunity for developing innovative semi-finished products, even if it can promote an increased quality degradation rate. The aim of this study was to evaluate physico-chemical modifications of mechanically separated mantis shrimp flesh during deep-freezing storage. Flesh samples obtained using a belt-drum separator, frozen and vacuum-packed, were stored at 3 temperatures (industrial: −26 °C; d

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Schulze, Ryan J., and Mark A. McNiven. "Lipid Droplet Formation and Lipophagy in Fatty Liver Disease." Seminars in Liver Disease 39, no. 03 (2019): 283–90. http://dx.doi.org/10.1055/s-0039-1685524.

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AbstractLipid droplets (LDs) are key sites of neutral lipid storage that can be found in all cells. Metabolic imbalances between the synthesis and degradation of LDs can result in the accumulation of significant amounts of lipid deposition, a characteristic feature of hepatocytes in patients with fatty liver disease, a leading indication for liver transplant in the United States. In this review, the authors highlight new literature related to the synthesis and autophagic catabolism of LDs, discussing key proteins and machinery involved in these processes. They also discuss recent findings that

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Kuentzel, Katharina B., Ivan Bradić, Alena Akhmetshina, et al. "Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth." International Journal of Molecular Sciences 22, no. 19 (2021): 10416. http://dx.doi.org/10.3390/ijms221910416.

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Cholesterol and fatty acids are essential lipids that are critical for membrane biosynthesis and fetal organ development. Cholesteryl esters (CE) are degraded by hormone-sensitive lipase (HSL) in the cytosol and by lysosomal acid lipase (LAL) in the lysosome. Impaired LAL or HSL activity causes rare pathologies in humans, with HSL deficiency presenting less severe clinical manifestations. The infantile form of LAL deficiency, a lysosomal lipid storage disorder, leads to premature death. However, the importance of defective lysosomal CE degradation and its consequences during early life are inc

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Raitio, Riikka, Vibeke Orlien, and Leif H. Skibsted. "Storage stability of cauliflower soup powder: The effect of lipid oxidation and protein degradation reactions." Food Chemistry 128, no. 2 (2011): 371–79. http://dx.doi.org/10.1016/j.foodchem.2011.03.038.

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Yang, Zhen, Ying Zhou, Jun-Jie Xing, Xiao-Na Guo, and Ke-Xue Zhu. "Influence of extrusion on storage quality of dried oat noodles: Lipid degradation and off-flavours." Journal of Cereal Science 101 (September 2021): 103316. http://dx.doi.org/10.1016/j.jcs.2021.103316.

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37

Locatelli-Hoops, Silvia, Natascha Remmel, Ralf Klingenstein, et al. "Saposin A Mobilizes Lipids from Low Cholesterol and High Bis(monoacylglycerol)phosphate-containing Membranes." Journal of Biological Chemistry 281, no. 43 (2006): 32451–60. http://dx.doi.org/10.1074/jbc.m607281200.

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Saposin A (Sap-A) is one of five known sphingolipid activator proteins required for the lysosomal degradation of sphingolipids and for the loading of lipid antigens onto antigen-presenting molecules of the CD1 type. Sap-A assists in the degradation of galactosylceramide by galactosylceramide-β-galactosidase in vivo, which takes place at the surface of intraendosomal/intralysosomal vesicles. Sap-A is believed to mediate the interaction between the enzyme and its membrane-bound substrate. Its dysfunction causes a variant form of Krabbe disease. In the present study we prepared glycosylated Sap-A

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Ryckman, Alex E., Inka Brockhausen, and Jagdeep S. Walia. "Metabolism of Glycosphingolipids and Their Role in the Pathophysiology of Lysosomal Storage Disorders." International Journal of Molecular Sciences 21, no. 18 (2020): 6881. http://dx.doi.org/10.3390/ijms21186881.

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Glycosphingolipids (GSLs) are a specialized class of membrane lipids composed of a ceramide backbone and a carbohydrate-rich head group. GSLs populate lipid rafts of the cell membrane of eukaryotic cells, and serve important cellular functions including control of cell–cell signaling, signal transduction and cell recognition. Of the hundreds of unique GSL structures, anionic gangliosides are the most heavily implicated in the pathogenesis of lysosomal storage diseases (LSDs) such as Tay-Sachs and Sandhoff disease. Each LSD is characterized by the accumulation of GSLs in the lysosomes of neuron

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Sugden, M. C., and M. J. Holness. "Substrate interactions in the development of insulin resistance in type II diabetes and obesity." Journal of Endocrinology 127, no. 2 (1990): 187–90. http://dx.doi.org/10.1677/joe.0.1270187.

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Introduction Theories for the mechanisms underlying the development of insulin resistance have included defects in insulin binding, inhibition of insulin receptor tyrosine kinase, and impaired translocation of glucose across the plasma membrane. However, little attention has been paid to the possibility that altered reciprocal regulatory interactions between lipid and carbohydrate fuels may underly the development of insulin resistance. We would like to review recent developments in metabolic regulation which indicate that this neglected aspect of intermediary metabolism may have more widespre

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Rahman, Muhammad Arifur, Ravinder Kumar, Enrique Sanchez, and Taras Y. Nazarko. "Lipid Droplets and Their Autophagic Turnover via the Raft-Like Vacuolar Microdomains." International Journal of Molecular Sciences 22, no. 15 (2021): 8144. http://dx.doi.org/10.3390/ijms22158144.

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Although once perceived as inert structures that merely serve for lipid storage, lipid droplets (LDs) have proven to be the dynamic organelles that hold many cellular functions. The LDs’ basic structure of a hydrophobic core consisting of neutral lipids and enclosed in a phospholipid monolayer allows for quick lipid accessibility for intracellular energy and membrane production. Whereas formed at the peripheral and perinuclear endoplasmic reticulum, LDs are degraded either in the cytosol by lipolysis or in the vacuoles/lysosomes by autophagy. Autophagy is a regulated breakdown of dysfunctional

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Brackmann, A., J. Streif, and F. Bangerth. "Relationship between a Reduced Aroma Production and Lipid Metabolism of Apples after Long-term Controlled-atmosphere Storage." Journal of the American Society for Horticultural Science 118, no. 2 (1993): 243–47. http://dx.doi.org/10.21273/jashs.118.2.243.

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`Golden Delicious' apples (Malus domestica Borkh.) harvested at the preclimacteric and climacteric stages of ripening were stored for up to 8 months at 1C in air and under various controlled atmosphere(s) (CA), including ultralow oxygen (ULO) storage conditions. Aroma volatiles were measured at 2-month intervals in fruit ripened for 10 days at 20C. Fruits harvested at the climacteric stage produced more volatiles during all storage conditions than preclimacteric fruit. All CA storage treatments suppressed aroma production compared to cold storage. The greatest reduction was found under ULO (1%

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Rutkowska, Jaroslawa, Agata Antoniewska, Montserrat Martinez-Pineda, Agnieszka Nawirska-Olszańska, Anna Zbikowska, and Damian Baranowski. "Black Chokeberry Fruit Polyphenols: A Valuable Addition to Reduce Lipid Oxidation of Muffins Containing Xylitol." Antioxidants 9, no. 5 (2020): 394. http://dx.doi.org/10.3390/antiox9050394.

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The study aimed at assessing effects of black chokeberry polyphenol extract (ChPE) added (0.025–0.075%) to xylitol-containing muffins to reduce lipid oxidation, especially in preventing degradation of hydroperoxides throughout the storage period. Among polyphenolic compounds (3092 mg/100 g in total) in ChPE, polymeric procyanidins were the most abundant (1564 mg/100 g). ChPE addition resulted in a significantly increased capacity of scavenging free radicals and markedly inhibited hydroperoxides decomposition, as reflected by low anisidine values (AnV: 3.25–7.52) throughout the storage. On the

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Kukaittinun, Kornuma, and Chutimon Satirapipathkul. "Solid Lipid Nanoparticles from Active Compounds of Mango Seed Kernel Extract." Key Engineering Materials 675-676 (January 2016): 65–68. http://dx.doi.org/10.4028/www.scientific.net/kem.675-676.65.

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The bioactive compounds in Mango seed kernel have high antioxidant activities which can be used as an ingredient in cosmetic products. The aim of this study was to improve the stability of bioactive compound in seed kernel extract by preparation in the form of solid lipid nanoparticles (SLN). Solid lipid nanoparticles (SLN) were prepared by high-speed homogenization technique. The effect of formulation on introduction the extract in to the base solid lipid nanoparticle system was investigated. At the optimal condition, the particle size was 329.1 nm. The highest load efficiency was 89.12%. The

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Radom, J., R. Salvayre, T. Levade, and L. Douste-Blazy. "Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein–Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects." Biochemical Journal 269, no. 1 (1990): 107–13. http://dx.doi.org/10.1042/bj2690107.

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The uptake and intracellular metabolism of 4-(1-pyrene)butanoic acid (P4), 10-(1-pyrene)decanoic acid (P10) and 12-(1-pyrene)dodecanoic acid (P12) were investigated in cultured lymphoid cell lines from normal individuals and from a patient with multisystemic lipid storage myopathy (MLSM). The cellular uptake was shown to be dependent on the fatty-acid chain length, but no significant difference in the uptake of pyrene fatty acids was observed between MLSM and control lymphoid cells. After incubation for 1 h the distribution of fluorescent fatty acids taken up by the lymphoid cell lines also di

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Thazar-Poulot, Nelcy, Martine Miquel, Isabelle Fobis-Loisy, and Thierry Gaude. "Peroxisome extensions deliver the Arabidopsis SDP1 lipase to oil bodies." Proceedings of the National Academy of Sciences 112, no. 13 (2015): 4158–63. http://dx.doi.org/10.1073/pnas.1403322112.

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Lipid droplets/oil bodies (OBs) are lipid-storage organelles that play a crucial role as an energy resource in a variety of eukaryotic cells. Lipid stores are mobilized in the case of food deprivation or high energy demands—for example, during certain developmental processes in animals and plants. OB degradation is achieved by lipases that hydrolyze triacylglycerols (TAGs) into free fatty acids and glycerol. In the model plant Arabidopsis thaliana, Sugar-Dependent 1 (SDP1) was identified as the major TAG lipase involved in lipid reserve mobilization during seedling establishment. Although the

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Karlsdottir, Magnea, Sigurjon Arason, Kristin Thorarinsdottir, Minh Van Nguyen, and Hordur Kristinsson. "Lipid Degradation of Cod Liver During Frozen Storage as Influenced by Temperature, Packaging Method, and Seasonal Variation." Journal of Aquatic Food Product Technology 25, no. 6 (2015): 802–10. http://dx.doi.org/10.1080/10498850.2014.932315.

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Mahmoodani, Fatemeh, Conrad O. Perera, Grant Abernethy, Bruno Fedrizzi, and Hong Chen. "Lipid oxidation and vitamin D3 degradation in simulated whole milk powder as influenced by processing and storage." Food Chemistry 261 (September 2018): 149–56. http://dx.doi.org/10.1016/j.foodchem.2018.04.043.

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Colla, L. M., C. D. Bertol, D. J. Ferreira, J. Bavaresco, J. A. V. Costa, and T. E. Bertolin. "Thermal and photo-stability of the antioxidant potential of Spirulina platensis powder." Brazilian Journal of Biology 77, no. 2 (2016): 332–39. http://dx.doi.org/10.1590/1519-6984.14315.

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Abstract This work aimed to evaluate the thermal and photo stability of the antioxidant potential (AP) of the Spirulina platensis biomass. Thermal stability was established at 25ºC, 40ºC and 50ºC for 60 days, in the dark, protected from light. Photo stability was evaluated using UV (15 W, λ = 265 nm) and fluorescent (20 W, 0.16 A, power factor FP > 0.5, 50/60 Hz, 60 lm/w, 1200 lm) light for 90 days in capsules, glass and Petri dishes, at room temperature. The AP of the biomass in these conditions was determined at intervals (every 7 and 30 days in the studies of thermal and photo stability,

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Nlelsen, Henrik K., J. Löliger, and R. F. Hurrell. "Reactions of proteins with oxidizing lipids." British Journal of Nutrition 53, no. 1 (1985): 61–73. http://dx.doi.org/10.1079/bjn19850011.

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1. The reactions between protein-bound amino acids and oxidizing lipid were investigated in a whey protein-methyl linolenate (C18.3)–water model system. The extent of fat oxidation was followed by measuring oxygen uptake, hydroperoxide formation and hydrocarbon (ethane and pentane) formation.2. Significant losses occurred with lysine (up to 71 %), tryptophan (up to 31 %) and histidine (up to 57%). Methionine was extensively oxidized to its sulphoxide but less than 2% was further oxidized to the sulphone. No other amino acids were affected.3. Increasing storage temperature (20°, 37°, 55°) resul

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Monteiro, Maria Lúcia G., Eliane T. Mársico, and Carlos A. Conte-Junior. "Application of Active Packaging in Refrigerated Rainbow Trout (Oncorhynchus mykiss) Fillets Treated with UV-C Radiation." Applied Sciences 10, no. 17 (2020): 5787. http://dx.doi.org/10.3390/app10175787.

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This study investigated the effects of oxygen-scavenger packaging and UV-C radiation at two doses, alone or in combination, on lipid oxidation (malondialdehyde levels), protein oxidation (carbonyl content), instrumental color and texture parameters in rainbow trout fillets stored at 4 ± 1 °C for 9 days. The treatments were AP (air packaging), OSP (oxygen-scavenger packaging), AUV1 (air packaging + UV-C at 0.102 J/cm2), OSUV1 (oxygen-scavenger packaging + UV-C at 0.102 J/cm2), AUV3 (air packaging + UV-C at 0.301 J/cm2), and OSUV3 (oxygen-scavenger packaging + UV-C at 0.301 J/cm2). Lipid oxidati

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