Academic literature on the topic 'Strecker reaction; Trimethylsilyl cyanide'

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Journal articles on the topic "Strecker reaction; Trimethylsilyl cyanide"

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Najar, Asef H., Zinatossadat Hossaini, Shahrzad Abdolmohammadi та Daryoush Zareyee. "ZnO-nanorods Promoted Synthesis of α-amino Nitrile Benzofuran Derivatives using One-pot Multicomponent Reaction of Isocyanides". Combinatorial Chemistry & High Throughput Screening 23, № 4 (2020): 345–55. http://dx.doi.org/10.2174/1386207323666200219124625.

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Aims & Objective: In this work ZnO-nanorod (ZnO-NR) as reusable catalyst promoted Strecker-type reaction of 2,4-dihydroxyacetophenone, isopropenylacetylene, trimethylsilyl cyanide (TMSCN), primary amines and isocyanides at ambient temperature under solvent-free conditions and produced α-amino nitriles benzofuran derivatives in high yields. These synthesized compounds may have antioxidant ability. Materials and Methods: ZnO-NRs in these reactions were prepared according to reported article. 2,4-dihydroxyacetophenone 1 (2 mmol) and isopropenylacetylene 2 (2 mmol) were mixed and stirred for 3
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Madadi, Elaheh. "Strecker Synthesis of α-aminonitriles Facilitated by N-methyl Imidazolium Acetate". Alinteri Journal of Agriculture Sciences 36, № 1 (2021): 323–27. http://dx.doi.org/10.47059/alinteri/v36i1/ajas21048.

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N-Methyl imidazolium acetate [HMIm]OAc was simply prepared through reaction of N-methyl imidazole with acetic acid and it was applied as a media and promoter for Strecker synthesis of α-aminonitriles. The three component reaction of a variety of structurally different aldehydes and amines with trimethylsilyl cyanide (TMSCN) in the presence of [HMIm]OAc were evaluated. Reaction of aromatic aldehydes and cinnamaldehyde with either aromatic and aliphatic amines provided the corresponding α-aminonitriles in high to excellent isolated yields after short period of time at room temperature.
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Zhang, Guang-Wu, Dong-Hua Zheng, Jing Nie, Teng Wang, and Jun-An Ma. "Brønsted acid-catalyzed efficient Strecker reaction of ketones, amines and trimethylsilyl cyanide." Organic & Biomolecular Chemistry 8, no. 6 (2010): 1399. http://dx.doi.org/10.1039/b924272d.

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Takahashi, Eiki, Hidehiko Fujisawa, Toshiharu Yanai, and Teruaki Mukaiyama. "Lewis Base-catalyzed Diastereoselective Strecker-type Reaction between Trimethylsilyl Cyanide and Chiral Sulfinimines." Chemistry Letters 34, no. 4 (2005): 604–5. http://dx.doi.org/10.1246/cl.2005.604.

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Zhang, Guang-Wu, Dong-Hua Zheng, Jing Nie, Teng Wang, and Jun-An Ma. "ChemInform Abstract: Broensted Acid-Catalyzed Efficient Strecker Reaction of Ketones, Amines and Trimethylsilyl Cyanide." ChemInform 41, no. 31 (2010): no. http://dx.doi.org/10.1002/chin.201031082.

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Takahashi, Eiki, Hidehiko Fujisawa, Toshiharu Yanai, and Teruaki Mukaiyama. "Lewis Base-catalyzed Strecker-type Reaction between Trimethylsilyl Cyanide andN-Tosylimines in Water-containing DMF." Chemistry Letters 34, no. 3 (2005): 318–19. http://dx.doi.org/10.1246/cl.2005.318.

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Jiao, Zhigang, Xiaoming Feng, Bo Liu, Fuxue Chen, Guolin Zhang, and Yaozhong Jiang. "Enantioselective Strecker Reactions between Aldimines and Trimethylsilyl Cyanide Promoted by ChiralN,N′-Dioxides." European Journal of Organic Chemistry 2003, no. 19 (2003): 3818–26. http://dx.doi.org/10.1002/ejoc.200300319.

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Gal, Emese, Luiza Gaina, Hermina Petkes, et al. "Ultrasound-assisted Strecker synthesis of novel 2-(hetero)aryl-2-(arylamino)acetonitrile derivatives." Beilstein Journal of Organic Chemistry 16 (November 30, 2020): 2929–36. http://dx.doi.org/10.3762/bjoc.16.242.

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This work describes an efficient, simple, and ecofriendly sonochemical procedure for the preparation of new α-(arylamino)acetonitrile derivatives C-substituted with phenothiazine or ferrocene units. The synthetic protocol is based on the Strecker reaction of a (hetero)aryl aldimine substrate with trimethylsilyl cyanide (TMSCN) in poly(ethylene glycol) (PEG) solution. The advantages of the sonochemical versus the conventional α-(arylamino)acetonitrile synthesis are the significantly shorter reaction time (30 min instead of 72 hours), the higher purity and the easier separation of the product th
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Lu, Yongping, Yanping Wang та Xingxian Zhang. "MgI2 Etherate-Catalysed Strecker Reaction: A Facile and Efficient Synthesis of α-Aminonitriles from Aldimines and Trimethylsilyl Cyanide". Journal of Chemical Research 37, № 11 (2013): 709–11. http://dx.doi.org/10.3184/174751913x13817705381783.

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Mojtahedi, Mohammad M., M. Saeed Abaee та Hassan Abbasi. "One-pot, solvent-free synthesis of α-aminonitriles under catalysis by magnesium bromide ethyl etherate". Canadian Journal of Chemistry 84, № 3 (2006): 429–32. http://dx.doi.org/10.1139/v06-024.

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A three-component, efficient, and facile procedure has been developed for the synthesis of α-aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds.Key words: catalyzed Strecker's reaction, α-aminonitriles, magnesium bromide, solvent-free.
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Dissertations / Theses on the topic "Strecker reaction; Trimethylsilyl cyanide"

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Jones, Catrin A. "The asymmetric synthesis of #alpha#-amino acids from imines." Thesis, Bangor University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263167.

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Grosjean, Christophe. "The Strecker reaction of benzaldehyde, amines and cyanide : some mechanistic and synthetic studies." Thesis, Durham University, 2004. http://etheses.dur.ac.uk/3043/.

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The Strecker reaction involves the formation of aminonitriles by the reaction of an aldehyde with an amine in the presence of cyanide ions. In this work kinetic, equilibrium and synthetic measurements have been made using benzaldehyde, or 4-nitrobenzaldehyde, as the aldehyde and benzylamine or allylamine as the amine. A side reaction involves the formation of a cyanohydrin from benzaldehyde and cyanide ion. The equilibria involved m the reaction and their pH dependence have been examined. For comparison values for the equilibrium constants for the reaction of benzaldehyde with sulfite are also
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Book chapters on the topic "Strecker reaction; Trimethylsilyl cyanide"

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Hof, K., K. M. Lippert, and P. R. Schreiner. "Strecker Reaction: Catalytic Addition of Hydrogen Cyanide or Trimethylsilyl Cyanide to Aldimines." In Brønsted Base and Acid Catalysts, and Additional Topics. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00257.

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Hof, K., K. M. Lippert, and P. R. Schreiner. "Strecker Reaction: Catalytic Addition of Hydrogen Cyanide or Trimethylsilyl Cyanide to Ketimines." In Brønsted Base and Acid Catalysts, and Additional Topics. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00258.

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Black, D. StC. "Reaction of Trimethylsilyl Cyanide with Alkynes, Catalyzed by Palladium(II) or Nickel(II) Chloride." In Fully Unsaturated Small-Ring Heterocycles and Monocyclic Five-Membered Hetarenes with One Heteroatom. Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-009-00551.

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