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1

Yang, Yao, Yuenying Wong, Yujie Li, et al. "Clinical Features, Antibiotic Susceptibilities, and Outcomes of Endophthalmitis Caused by Streptococcal Infection: Children vs. Adults." Antibiotics 12, no. 6 (2023): 962. http://dx.doi.org/10.3390/antibiotics12060962.

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Streptococcus spp. are common causative organisms of endophthalmitis. Analysis of the clinical features, antibiotic susceptibilities, and outcomes of streptococcal endophthalmitis in children and adults may guide future management. Sixty-seven patients (67 eyes) with streptococcal endophthalmitis who were admitted to the Zhongshan Ophthalmic Center between January 2013 and December 2022 were retrospectively reviewed. The mean age was 20.7 ± 21.6 years, and 59.7% were children. Streptococcal infection accounted for 13.9% of culture-proven bacterial endophthalmitis cases; the proportion was high
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2

Kaytukov, A. O., E. V. Glushkova, N. I. Briko, et al. "Soft Tissue Infections of Streptococcal Etiology in the Purulent-Surgical Department of a Multidisciplinary Hospital." Epidemiology and Vaccinal Prevention 24, no. 2 (2025): 14–23. https://doi.org/10.31631/2073-3046-2025-24-2-14-23.

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Purulent diseases of skin and soft tissues occupy the leading place among surgical infections in terms of frequency of occurrence and possible complications. The most significant etiological agents in surgical infections of soft tissues are group A streptococci (SGA), however, there are known cases of severe invasive infections caused by group B, C, G streptococci and pneumococci.Aim. To estimate the frequency and identify the features of soft tissue streptococcal infection in patients of the purulent-surgical department of a multidisciplinary hospital in Moscow.Materials and Methods. We condu
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3

Pypa, L. V., K. Yu Kreniov, L. V. Dudikova, et al. "Analysis of cases of severe streptococcal infection in children and adults in Khmelnytskyi region." CHILD`S HEALTH 19, no. 7 (2024): 445–50. https://doi.org/10.22141/2224-0551.19.7.2024.1756.

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Background. Group A beta-hemolytic streptococcus (Streptococcus pyogenes) is a widespread bacterial pathogen that can cause many clinical variants of diseases in humans and be a trigger factor for the development of various autoimmune conditions. The purpose of the study was to show the current state of infection caused by group A beta-hemolytic streptococcus in adults and children using case studies. Materials and methods. The article describes 5 cases of streptococcal infection caused by Str.pyogenes with different clinical symptoms. The streptococcal etiology was confirmed by bacteriologica
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4

Ivanova, L. A., I. B. Horbatiuk, and Ir B. Horbatiuk. "Clinical and paraclinical markers of inflammatory activity in acute tonsilopharyngitis in children." Modern pediatrics. Ukraine, no. 2(114) (March 27, 2021): 8–12. http://dx.doi.org/10.15574/sp.2021.114.8.

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Purpose — to study clinical and paraclinical markers of inflammatory activity in acute non-streptococcal and streptococcal tonsillopharyngitis in children to address rational treatment tactics. Materials and methods. To achieve this goal, a comprehensive examination of 102 children with acute tonsillopharyngitis, which was divided into two clinical groups depending on the isolation of beta-hemolytic streptococcus group A during a culture of smears from the mucosa of the tonsils/pharynx. The first (I) clinical group included 68 patients in whom bacteriological examination did not reveal BGSA —
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5

Galeone, Massimiliano, Roberta Colucci, Angelo Massimiliano D'Erme, Silvia Moretti, and Torello Lotti. "Potential Infectious Etiology of Behçet's Disease." Pathology Research International 2012 (December 29, 2012): 1–4. http://dx.doi.org/10.1155/2012/595380.

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Behçet's disease is a multisystem inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. The cause of Behçet's disease remains unknown, but epidemiologic findings suggest that an autoimmune process is triggered by an environmental agent in a genetically predisposed individual. An infectious agent could operate through molecular mimicry, and subsequently the disease could be perpetuated by an abnormal immune response to an autoantigen in the absence of ongoing infection. Potentia bacterial are Saccharomyces cerevisiae, mycobacteria, Bor
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6

Çiçek, Yasin, Mehmet Özgöz, Varol Çanakçi, and Recep Orbak. "Streptococcal Gingivitis: A Report of Case with a Description of a Unique Gingival Prothesis." Journal of Contemporary Dental Practice 5, no. 3 (2004): 150–57. http://dx.doi.org/10.5005/jcdp-5-3-150.

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Abstract Acute streptococcal gingivitis is an acute inflammation of the oral mucosa. Specific bacterial infections of the gingiva may be due to neisseria gonorrhea, treponema pallidum, streptococci, and other organisms. Streptococcal infections are seen rarely. This case report describes a patient who presented with severe gingival inflammation and pain that was diagnosed as an acute streptococcal infection. Bacterial cultures were obtained from the lesion, and biopsies were obtained from the gingiva of lower incisors for histopathologic evaluation. The patient was successfully treated using c
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7

Burova, Larisa A., Alexander N. Suvorov, Peter V. Pigarevsky, and Artem A. Totolian. "Autoimmune streptococcal glomerulonephritis: the problem of nephritogenicity of <i>Streptococcus pyogenes</i>." Russian Journal of Infection and Immunity 13, no. 3 (2023): 409–29. http://dx.doi.org/10.15789/2220-7619-asg-8491.

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Acute post-streptococcal glomerulonephritis usually occurs as a complication after a streptococcal infection due to untimely or inadequate antibiotic therapy. The etiology of post-streptococcal glomerulonephritis has been studied rather comprehensively. Today, both clinicians and microbiologists do not deny the dominant role of Streptococcus pyogenes (streptococcus attributed to serological group A, GAS). Usually, emergence of acute post-streptococcal glomerulonephritis (APSGN) is associated with the so-called GAS-related "nephritogenicity" often judged by appearance and accumulation of antibo
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8

Laknitskaya, Anastasiya. "Etiology, clinical presentation, laboratory diagnostics, pathogenesis of impetigo and treatment methods." Terapevt (General Physician), no. 3 (March 1, 2020): 64–70. http://dx.doi.org/10.33920/med-12-2003-07.

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Currently, one of the priority medical and social problems is the optimization of treatment methods for pyoderma associated with Streptococcus pyogenes — group A streptococcus (GAS). To date, the proportion of pyoderma, the etiological factor of which is Streptococcus pyogenes, is about 6 % of all skin diseases and is in the range from 17.9 to 43.9 % of all dermatoses. Role of the bacterial factor in the development of streptococcal pyoderma is obvious. Traditional treatment complex includes antibacterial drugs selected individually, taking into account the antibiotic sensitivity of pathognomo
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9

Shcherbatenko, S. I. "Treatment for rheumatoid arthritis." Kazan medical journal 43, no. 5 (2021): 53–55. http://dx.doi.org/10.17816/kazmj87788.

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Department of Faculty Therapy (Head - Prof. Z. I. Malkin) Kazan Medical Institute With regard to the etiology of rheumatoid arthritis, the most acute, controversial issue is the role of infection. ) A.I. Nesterov believes that streptococcal infection plays the role of a trigger mechanism. Streptococcus creates a lesion that leads to a toxic-allergic reaction from the joints. In accordance with this, Nesterov devotes a significant place to the treatment of rheumatoid arthritis with antibiotics in parallel with desensitizing therapy.
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10

Gorton, Davina, Brenda Govan, Colleen Olive, and Natkunam Ketheesan. "B- and T-Cell Responses in Group A Streptococcus M-Protein- or Peptide-Induced Experimental Carditis." Infection and Immunity 77, no. 5 (2009): 2177–83. http://dx.doi.org/10.1128/iai.01514-08.

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ABSTRACT The etiology of rheumatic fever and rheumatic heart disease (RF/RHD) is believed to be autoimmune, involving immune responses initiated between streptococcal and host tissue proteins through a molecular mimicry mechanism(s). We sought to investigate the humoral and cellular responses elicited in a Lewis rat model of group A streptococcus M-protein- or peptide-induced experimental valvulitis/carditis, a recently developed animal model which may, in part, represent human rheumatic carditis. Recombinant streptococcal M5 protein elicited opsonic antibodies in Lewis rats, and anti-M5 antis
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11

Leśnik, Patrycja, Jarosław Janc, Martyna Biała, Marzenna Bartoszewicz, Lidia Łysenko, and Natalia Słabisz. "Old Bug—New Challenges After COVID-19 Pandemic: Severe Invasive Streptococcus pyogenes Infections in Adults—A Single-Center Experience in Poland." Pathogens 14, no. 2 (2025): 199. https://doi.org/10.3390/pathogens14020199.

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Since the beginning of December 2022, an unusually high number of cases and deaths of Group A Streptococcus (GAS) infections has been reported in many European countries. GAS infection frequently causes mild diseases such as pharyngitis, tonsillitis, impetigo, cellulitis, and scarlet fever. However, in rare instances, GAS infection can lead to invasive, life-threatening conditions like necrotizing fasciitis and toxic shock syndrome, which are associated with high mortality. The aim of the study was to present the clinical course of invasive Streptococcus pyogenes infections and to highlight th
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12

Banas, Jeffrey A., Min Zhu, Deborah V. Dawson, Huojun Cao, and Steven M. Levy. "PCR-Based Identification of Oral Streptococcal Species." International Journal of Dentistry 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/3465163.

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The microbial etiology of dental caries is still debated. Among the hypothesized contributors are the “low pH streptococci,” a designation given to unusually acid proficient strains among the primary plaque colonizersS. oralis,S. mitis,S. gordonii, andS. anginosus. However, accurate assignment of species is difficult among the oral streptococci. Our objective was to develop a streamlined method for identifying strains ofS. oralisandS. mitisfrom plaque samples so that they could be analyzed in a separate study devoted to low pH streptococci and caries. Two independent PCR amplifications of a lo
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13

Oganyan, Kristina Al’bertovna, Ol’ga Nikolaevna Arzhanova, Alevtina Mikhaylovna Savicheva, and Svetlana L’vovna Zatsiorskaya. "Prophylactic antimicrobial drugs to pregnant women colonized with group B streptococcus." Journal of obstetrics and women's diseases 64, no. 2 (2015): 59–63. http://dx.doi.org/10.17816/jowd64259-63.

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Group B streptococcus (GBS), Streptococcus agalactiae, are the causative agents of severe infection of the fetus and newborn child. The aim of the study was to evaluate the efficacy of antibacterial drugs in women in the III trimester of pregnancy for the prevention of B streptococcal infection. Studied during childbirth and the postpartum period, 70 women colonized by group B streptococcus, treated and not treated with antibacterial perparaty in the III trimester of pregnancy. Evaluated as a new-born children of these women. In pregnant women who received antibiotics in the III trimester of p
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14

Sutawan, Ida Bagus Ramajaya, Azwin Mengindra Putera, Zahrah Hikmah, and Anang Endaryanto. "Urticarial vasculitis associated with post-streptococcal disease in children: a case report." Bali Medical Journal 12, no. 1 (2023): 501–5. http://dx.doi.org/10.15562/bmj.v12i1.3841.

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Background: Urticarial vasculitis (UV) is a rare clinicopathologic, especially among children and infants. Most urticarial vasculitis is caused by unknown etiology. Rarely has it been linked to post-streptococcal disease as a non-suppurative complication of a streptococcus infection. Treatment of urticarial vasculitis can be challenging. It is based on the clinical phenotype, systemic symptoms, and/or underlying diseases. Case Presentation: This study reports a case of a child with an itchy but more painful and burning sensations urticarial lesion which persisted for more than 24 hours, left a
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15

Maltseva, G. S., and O. N. Grinchuk. "Role of antibiotic therapy in the treatment of streptococcal infection." Medical Council, no. 20 (November 16, 2019): 91–96. http://dx.doi.org/10.21518/2079-701x-2019-20-91-96.

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The article states the principles for antibiotic therapy for chronic tonsillitis (CT) and acute tonsillopharyngitis (ATP). The greatest attention is paid to the non-angina CT, when the patients, as a general rule, are deprived of antibiotic therapy. At the same time, the article provides data of St. Petersburg Research Institute of ENT, whereby at least 40% of patients with CT have streptococcal etiology of the disease caused by group A beta-hemolytic streptococci (GABHS) that is confirmed by not only bacteriological, but also immunological research methods (increase in antistreptolysin-O). In
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16

Loza, Samantha, Brandon Tallman, Keith Hanson, and Shane Rainey. "A 15-year-old with chest pain: An unexpected etiology." SAGE Open Medical Case Reports 10 (January 2022): 2050313X2110690. http://dx.doi.org/10.1177/2050313x211069026.

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A 15-year-old female with no significant past medical history presented to the emergency department with 1 day of substernal and pleuritic chest pain, chills, cough, and hematuria. She also had swelling of the face and ankles that resolved by presentation. She was found to have elevated troponin and brain natriuretic peptide during initial workup. Electrocardiogram was normal, but there were significant pleural effusions on chest x-ray. She was strep positive and had blood pressure up to 150/90, prompting admission for cardiac monitoring and cardiology consultation. Blood pressure decreased do
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17

Putto, Anne. "Febrile Exudative Tonsillitis: Viral or Streptococcal?" Pediatrics 80, no. 1 (1987): 6–12. http://dx.doi.org/10.1542/peds.80.1.6.

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A prospective 1-year study of acute febrile exudative tonsillitis in 110 children was carried out. Viral infection was associated with 42% of the cases, β-hemolytic streptococci with 31% (12% group A), Mycoplasma pneumoniae with 5%, and unknown cause with 35%. More than one agent was implicated in 14% of the cases. Adenovirus was the viral agent most frequently (19%) recorded. Other viruses involved were Epstein-Barr virus, parainfluenza, influenza A, herpes simplex, and respiratory syncytial viruses. The responsible agent was found by rapid viral antigen detection in 20% of all cases and by r
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18

Barzilai, Asher, Dan Miron, and Shlomo Sela. "Etiology and management of acute and recurrent group a Streptococcal tonsillitis." Current Infectious Disease Reports 3, no. 3 (2001): 217–23. http://dx.doi.org/10.1007/s11908-001-0023-6.

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19

Gunasekaran, Gayathri, Dinesh Kumar Thirugnanam, and N. Nalini Jayanthi. "Beta-hemolytic Streptococci in respiratory illness." Bioinformation 20, no. 11 (2024): 1495–99. https://doi.org/10.6026/9732063002001495.

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Beta-hemolytic streptococci are associated with various respiratory illnesses, such as pharyngitis, scarlet fever, and pneumonia, highlighting the need for enhanced diagnostic, therapeutic, and preventive strategies. Advances in immunology and molecular biology have provided insights into the etiology and host immune responses to these infections, but many questions remain unanswered. Further research is needed to develop advanced diagnostics, explore vaccine candidates, understand immune responses, and address antibiotic resistance. Epidemiological studies are crucial to improving our underst
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20

Murase, Toshiyuki, Rieko Suzuki, Ro Osawa, and Shiro Yamai. "Characteristics of Streptococcus pyogenes Serotype M1 and M3 Isolates from Patients in Japan from 1981 to 1997." Journal of Clinical Microbiology 37, no. 12 (1999): 4131–34. http://dx.doi.org/10.1128/jcm.37.12.4131-4134.1999.

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Streptococcus pyogenes isolates obtained in 1981 to 1997 from patients and healthy subjects were characterized by pulsed-field gel electrophoresis (PFGE) patterns, biotyping, and the presence of spe genes encoding streptococcal pyrogenic exotoxins. Changes in the profiles were shown in the serotype M1/T1 isolates from pharyngitis over this period, but not in serotype M3/T3 isolates. The characteristics of isolates from patients with toxic shock-like syndrome (TSLS) were comparable to those of the other isolates, including those from healthy subjects. This finding suggests that further phenotyp
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21

Love, Robert M., Malcolm D. McMillan, Yoonsuk Park, and Howard F. Jenkinson. "Coinvasion of Dentinal Tubules byPorphyromonas gingivalis and Streptococcus gordonii Depends upon Binding Specificity of Streptococcal Antigen I/II Adhesin." Infection and Immunity 68, no. 3 (2000): 1359–65. http://dx.doi.org/10.1128/iai.68.3.1359-1365.2000.

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ABSTRACT Cell wall-anchored polypeptides of the antigen I/II family are produced by many species of oral streptococci. These proteins mediate adhesion of streptococci to salivary glycoproteins and to other oral microorganisms and promote binding of cells to collagen type I and invasion of dentinal tubules. Since infections of the root canal system have a mixed anaerobic bacterial etiology, we investigated the hypothesis that coadhesion of anaerobic bacteria with streptococci may facilitate invasive endodontic disease. Porphyromonas gingivalis ATCC 33277 cells were able to invade dentinal tubul
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22

Borisova, O. V., N. M. Bochkareva, N. S. Polezhaeva, A. A. Frank, and O. N. Yashkina. "Application of a herbal preparation in the therapy of acute tonzillopharyngitis in children." Meditsinskiy sovet = Medical Council, no. 17 (November 1, 2021): 128–35. http://dx.doi.org/10.21518/2079-701x-2021-17-128-135.

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Introduction. Tonsillopharyngitis often accompanies the course of acute respiratory infections in children (up to 12-15%). The use of systemic antibacterial drugs for viral etiology of the disease has not been shown, therefore, the interest of researchers in the use of herbal products is increasing. In numerous clinical trials conducted around the world, the liquid extract of the roots of Pelargonium sidoides EPs® 7630 has been shown to be effective and safe in the treatment of acute respiratory infections, acute tonsillopharyngitis, rhinosinusitis, acute bronchitis in adults and children.Obje
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23

Колоскова, Е. К., Л. А. Иванова, И. Б. Горбатюк, et al. "Some Diagnostic Approaches to Verify the Etiology of Acute Tonsillopharyngitis in Children." Педиатрия. Восточная Европа, no. 2 (June 8, 2022): 218–25. http://dx.doi.org/10.34883/pi.2022.10.2.004.

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Введение. Значительная распространенность острыхтонзиллофарингитов (ОТФ) среди детского населения обуславливает актуальность проблемы своевременной диагностики и верной тактики этиотропного лечения данной патологии в педиатрии. Цель. Оценить результаты применения отдельных иммунологических тестов при выявлении нестрептококкового острого тонзиллофарингита у детей с целью оптимизации начального этиотропного лечения и нерелевантной антибактериальной терапии.Материалы и методы. Проведено проспективное исследование 102 пациентов с острым тонзиллофарингитом в возрасте от 3 до 18 лет, находившихся на
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24

Garashchenko, T. I., L. I. Ilenko, A. P. Yastremsky, and N. E. Payganova. "The role of topical therapy in the complex treatment of tonsillopharyngitis in children." Meditsinskiy sovet = Medical Council, no. 1 (April 3, 2025): 94–102. https://doi.org/10.21518/ms2025-105.

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Acute tonsillopharyngitis is a common disease (2–5% of paediatric outpatient visits) for which systemic antimicrobials are often prescribed. However, streptococcal tonsillopharyngitis, infection caused by group A beta-hemolytic streptococci (GABHS), is one of the main indications for antibiotic therapy in acute tonsillopharyngitis in children. When developing a treatment regimen for the disease, preference is given to topical therapy (except in cases of streptococcal tonsillopharyngitis), and the topical antimicrobial therapy methodology recognises that laryngospasm may occur in young children
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25

Swedo, Susan E., Marjorie Garvey, Lisa Snider, Charlotte Hamilton, and Henrietta L. Leonard. "The PANDAS Subgroup: Recognition and Treatment." CNS Spectrums 6, no. 5 (2001): 419–26. http://dx.doi.org/10.1017/s1092852900021799.

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AbstractA subgroup of patients with childhood-onset obsessive-compulsive disorder (OCD) has been identified who share a common clinical course characterized by dramatic symptom exacerbations following Group A beta-hemolytic streptococcal (GABHS) infections. The term PANDAS has been applied to the subgroup, to indicate the postulated etiology of their symptoms: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections. Five clinical characteristics define the PANDAS subgroup: presence of OCD and/or tic disorder, prepubertal symptom onset, sudden onset or abrupt ex
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26

Boyarchuk, O. R., O. M. Mochulska, N. I. Yarema, and I. M. Horishnyi. "Assessment of awareness regarding the diagnosis and management of pharyngitis in children among general practitioners." Modern pediatrics. Ukraine, no. 7(135) (November 28, 2023): 79–86. http://dx.doi.org/10.15574/sp.2023.135.79.

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Sore throat and pharyngitis account for up to 5.0% of all medical visits to a general practitioner. The etiology of pharyngitis in both adults and children is dominated by viruses, but in 20.0-30.0% of children the cause may be bacteria, most often the Group A β-hemolytic streptococcus. Purpose - to assess the knowledge of general practitioners regarding the diagnosis and management of pharyngitis in children, to determine further ways to increase their level of awareness. Materials and methods. A survey of 60 general practitioners in the Ternopil region of Ukraine was conducted to determine t
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27

Orishchak, Diana. "Acute Inflammatory Diseases of the Pharynx – the Role and Possibilities of Local Therapy." Family Medicine. European Practices, no. 1 (February 28, 2023): 51–56. https://doi.org/10.30841/2786-720X.1.2023.

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Acute inflammatory diseases of the pharynx (tonsillitis, pharyngitis, etc.) are the most common reasons for visits to the family doctor and otorhinolaryngologist at any time of the year. In 95 % of cases, these diseases are caused by a viral infection (adenoviruses, influenza virus A and B, parainfluenza virus, herpes virus, enteroviruses, Coxsackie viruses), less often by group A Streptococcus. <strong>The objective:</strong>&nbsp;to analyze the clinical effectiveness of the local non-steroidal drug flurbiprofen in the treatment of acute viral pharyngitis and acute streptococcal tonsillitis i
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28

Haiduk, T., A.V. Cherhinets, and L.R. Shostakovych-Koretska. "Effect of antibacterial therapy on the clinical course of streptococcal tonsillopharyngitis in children." Medicni perspektivi 24, no. 4 (2019): 69–74. https://doi.org/10.26641/2307-0404.2019.4.189264.

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The aim of this study was to determine the effect of antibiotic therapy (AT) on the clinical course of streptococcal tonsillopharyngitis (STP) in children, depending on the timing of its administration, since the data on the need to start AT in the first days of the disease to achieve the effect are controversial. A retrospective analysis of inpatient medical records at &ldquo;The Communal Dnipro City Clinical Hospital N&nbsp;21 named after Professor Ye.G. Popkova&rdquo; DRC&rdquo; in the period from January 2012 to December 2018 was conducted. The inclusion criteria for the study were: 1) the
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29

Bisno, Alan L. "Acute Pharyngitis: Etiology and Diagnosis." Pediatrics 97, no. 6 (1996): 949–54. http://dx.doi.org/10.1542/peds.97.6.949.

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Acute pharyngitis may be caused by a wide variety of microbial agents (Table 1). The relative importance of each of these agents varies greatly depending on a number of epidemiologic factors, including age of the patient, season of the year, and geographic locale. Viruses Most cases of acute pharyngitis are viral in etiology and involve the pharynx as well as other portions of the respiratory tract as manifestations of the common cold, influenza, or croup. Examples include the rhinoviruses, coronaviruses, influenza A and B, and the parainfluenza viruses. Certain viral infections causing sore t
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30

Muthanna, AbdulRahman, Nurainul Hana Shamsuddin, Aneesa Abdul Rashid, et al. "Diagnostic Accuracy of Centor Score for Diagnosis of Group A Streptococcal Pharyngitis among Adults in Primary Care Clinics in Malaysia." Malaysian Journal of Medical Sciences 29, no. 4 (2022): 88–97. http://dx.doi.org/10.21315/mjms2022.29.4.9.

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Background: Pharyngitis is a common presentation seen in general practice, but it is difficult to differentiate whether its etiology is viral or bacterial. The Centor score gives an approximation of the etiology of the pharyngitis, which informs physicians of the need to prescribe antibiotics. This study aimed to assess the validity of the Centor score in diagnosing Group A streptococcal (GAS) pharyngitis amongst adults in Malaysia. Methods: This cross-sectional study was conducted to compare the clinical criteria of the Centor score to the gold standard throat swab culture results amongst 215
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31

Burova, L. A., and A. A. Totolian. "Major pathogenicity factors of <i>Streptococcus pyogenes</i>." Russian Journal of Infection and Immunity 12, no. 1 (2021): 33–50. http://dx.doi.org/10.15789/2220-7619-mpf-1723.

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Streptococcal diseases and their complications are among the global problems of international health. S. pyogenes (group A streptococci — GAS) is a pathogen that causes significant morbidity in different countries and different age groups of the population, occurring both sporadically and epidemically. Due to ineffective antibacterial therapy or its absence, 3–5% of people who have had streptococcal infection may develop complications such as acute rheumatic fever, rheumatic heart disease, acute post-streptococcal glomerulonephritis and invasive complications: necrotizing fasciitis and myositi
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32

Guseva, A. L., and M. L. Derbeneva. "Differential diagnosis and effective therapy for sore throat." Meditsinskiy sovet = Medical Council, no. 18 (December 1, 2021): 166–71. http://dx.doi.org/10.21518/2079-701x-2021-18-166-171.

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Sore throat is a common complaint, which can be caused by a typical viral pharyngitis, or it can be rooted in a life-threatening disease such as epiglottitis or inflammation of the cellular spaces in the throat and neck. The doctor should take a closer look at a patient with a sore throat, immediately make a differential diagnosis and prescribe adequate treatment, including surgical intervention, if necessary.The article discusses the most common causes of a sore throat, including various types of pharyngitis, paratonsillar abscess, parapharyngeal abscess, retropharyngeal abscess, epiglottitis
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Ionov, S. N., Ya E. Nemstsveridze, R. I. Stepanova, K. D. Goncharov, and L. R. Derbina. "Influence of streptococcal infection on the appearance of caries in the background of chronic rheumatoid arthritis and the transmitted coronavirus infection COVID-19 (literature review)." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 13, no. 6 (2024): 117–24. http://dx.doi.org/10.20340/vmi-rvz.2023.6.clin.14.

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Relevance. Caries of hard dental tissues is one of the most common diseases throughout the world. It affects not only the primary teeth of children, but also the permanent teeth of adults, which can lead to serious consequences for human health. In recent years, the dental community has paid special attention to the possible connection between streptococcal infection and the development of caries, and therefore this topic is extremely relevant and requires detailed consideration. Chronic rheumatoid arthritis (CRA) is one of the most common joint diseases, which is characterized by inflammation
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Dayhes, Nikolai A., Alexander A. Baranov, Yurii V. Lobzin, et al. "Modern Clinical Guidelines for the Management of Patients with Acute Tonsillitis and Pharyngitis." Pediatric pharmacology 22, no. 2 (2025): 164–77. https://doi.org/10.15690/pf.v22i2.2897.

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Acute tonsillitis and pharyngitis are common infectious diseases of upper respiratory tract causing significant discomfort and various complications in patients. This article covers all the issues of tonsillitis and pharyngitis etiology, pathogenesis, classification. Modern clinical guidelines focus on optimizing the diagnosis, management, and prevention of these conditions, ensuring high quality of medical care.Centor, McIsaac, or FeverPAIN scores can be used for differential diagnosis of viral and streptococcal tonsillopharyngitis. Particular attention is given to the management tactics of p
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Koloskova, O. K., A. L. Kosakovskyi, L. A. Ivanova, and I. B. Horbatiuk. "Clinical scale of severity of the course of acute tonsillopharyngitis in children: justification and diagnostic possibilities." UKRAINIAN JOURNAL OF PERINATOLOGY AND PEDIATRICS, no. 1(93) (March 28, 2023): 37–44. http://dx.doi.org/10.15574/pp.2023.93.37.

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Purpose - to develop a simple, constellational clinical system for assessing the severity of the course of acute tonsillopharyngitis (ATP) in children to optimize etiotropic treatment by reducing unreasonable antibiotic therapy. Materials and methods. We observed 102 children with ATP. A developed scale for assessing the severity of the course of ATP was used to monitor children. Evaluation of clinical symptoms with calculation of points was carried out daily, during 7 days of inpatient treatment. For the purpose of comparative analysis, as a "golden" standard, we used the assessment of sympto
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36

Bryant, Amy E. "Biology and Pathogenesis of Thrombosis and Procoagulant Activity in Invasive Infections Caused by Group A Streptococci and Clostridium perfringens." Clinical Microbiology Reviews 16, no. 3 (2003): 451–62. http://dx.doi.org/10.1128/cmr.16.3.451-462.2003.

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SUMMARY Group A streptococcal necrotizing fasciitis/myonecrosis and Clostridium perfringens gas gangrene are two of the most fulminant gram-positive infections in humans. Tissue destruction associated with these infections progresses rapidly to involve an entire extremity. Multiple-organ failure is common, and morbidity and mortality remain high. Systemic activation of coagulation and dysregulation of the anticoagulation pathways contribute to the pathogenesis of many diverse disease entities of infectious etiology, and it has been our hypothesis that microvascular thrombosis contributes to re
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Genis-Mendoza, Alma Delia, Humberto Nicolini, Viana Manrique, et al. "Association of antibody titers and 5-HTTLPR gene polymorphisms in pediatric autoimmune neuropsychiatric disorder associated with streptococci." Salud mental 43, no. 4 (2020): 181–87. http://dx.doi.org/10.17711/sm.0185-3325.2020.025.

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Introduction. It has been hypothesized that pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS) etiology results from an abnormal immune response to streptococcal infection. There is evidence that the serotonergic system is involved in both obsessive-compulsive disorder (OCD) physiopathology and immunological processes. In the 5’ promoter region of 5-HTT, gene encoding for the serotonin transporter we can find the 5-HTTLPR polymorphism that has been associated with OCD. Being PANDAS a disorder with OCD symptoms and likely immune abnormalities, 5-HTT
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Egorova, О. А. "Local therapy of sore throat against the background of antibiotic resistance." Meditsinskiy sovet = Medical Council, no. 8 (May 17, 2022): 68–76. http://dx.doi.org/10.21518/2079-701x-2022-16-8-68-76.

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Sore throat is an acutely common health problem both in Russia and around the world as a whole. This is one of the most common reasons adults and children seek primary specialized care. The overuse and misuse of antibiotics, especially for viral infections of the respiratory tract, such as acute and exacerbation of chronic tonsillopharyngitis, greatly increases the risk of developing and spreading antibiotic resistance. Up to 80% of cases of sore throat have a viral etiology of the disease, and even when the infection is bacterial, except for pyogenic streptococcus, the vast majority of cases
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Drozdova, M. V., Yu S. Preobrazhenskaya, S. V. Ryazantsev, and S. S. Pavlova. "Inflammatory diseases of the pharynx in children." Meditsinskiy sovet = Medical Council, no. 1 (February 26, 2022): 51–57. http://dx.doi.org/10.21518/2079-701x-2022-16-1-51-57.

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Introduction. Inflammatory diseases of the lymphoid ring of the pharynx in children are widespread and account for more than 30% in the structure of ENT pathology. Lymphoid tissue, especially the palatine tonsils, largely determines the formation of local and general protective reactions of the child’s body.The aim of this work is to assess the efficacy and safety of using topical bacterial lysate in chronic tonsillitis of streptococcal and herpes viral etiology in frequently ill children.Materials and methods. The study was conducted on a sample of 31 children aged 7–17 who were treated in th
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Kalogeropoulou, E., S. Damianidou, and G. Vrioni. "Etiological diagnosis of streptococcal pharyngitis based on throat swab." ACTA MICROBIOLOGICA HELLENICA 59, no. 3 (2014): 37–47. https://doi.org/10.5281/zenodo.10017242.

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Sore throat is a common reason for consulting pediatricians and primary-care physicians. Most cases are of viral origin. Streptococcus pyogenes (Group A Streptococcus, GAS) is the most frequent etiology of bacterial pharyngitis, and may cause more than 30% of pharyngitis cases in paediatric patients and 5–10% of sore throats among adults. Culture remains the microbiological reference method for detection of S. pyogenes. A definitive diagnosis is based on the results of a throat culture. Unfortunately, accurate diagnosis is difficult because (1) the majority of sore throats are viral in origin,
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Olkhovska, Viktoriia, Zalina Yeloyeva, and Yevhen Olkhovskyi. "Non-specific factors of children protection with streptococcal tonsillitis and infected with herpes virus type 6." ScienceRise: Medical Science, no. 5(44) (September 30, 2021): 28–31. http://dx.doi.org/10.15587/2519-4798.2021.240151.

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The aim of the work was to study the characteristics of the response of non-specific protective factors in tonsillitis of streptococcal etiology in children infected and uninfected with HHV-6 infection at different periods of the disease. Materials and research methods. In 78 children aged 3–15 years, inflammation markers and phagocytic activity of peripheral blood neutrophils (PAN) were determined using the nitroblue tetrazolium reduction test. The studies were carried out in the acute period and in the period of convalescence. Mathematical and statistical processing of the data obtained was
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Viktoriia, Olkhovska, Yeloyeva Zalina, and Olkhovskyi Yevhen. "Non-specific factors of children protection with streptococcal tonsillitis and infected with herpes virus type 6." ScienceRise: Medical Science, no. 5 (44) (September 30, 2021): 28–31. https://doi.org/10.15587/2519-4798.2021.240151.

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<strong>The aim of the work</strong>&nbsp;was to study the characteristics of the response of non-specific protective factors in tonsillitis of streptococcal etiology in children infected and uninfected with HHV-6 infection at different periods of the disease. <strong>Materials and research methods.</strong>&nbsp;In 78 children aged 3&ndash;15 years, inflammation markers and phagocytic activity of peripheral blood neutrophils (PAN) were determined using the nitroblue tetrazolium reduction test. The studies were carried out in the acute period and in the period of convalescence. Mathematical an
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43

Rodin, A. V., and A. A. Shilina. "Selection of antibiotics to prevent recurrence of erysipelas." Нospital-replacing technologies:Ambulatory surgery, no. 3-4 (November 16, 2019): 65–72. http://dx.doi.org/10.21518/1995-1477-2019-3-4-65-72.

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Erysipelas is an acute infectious disease of streptococcal etiology. Currently, many people lead an active lifestyle, including sports activities both in outdoor areas and in gyms. There is always a risk of various wounds, which are the entry gate for infection, in particular Streptococcus pyogenes. Infection often occurs against the background of weakened immunity. Reduced immune properties can result from frequent stress and chronic fatigue due to severe physical and psycho-emotional stress at work. All these factors in combination create favorable conditions for the development of erysipela
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Atuhaire, Patience, Mary Kyohere, Valerie Tusubira, et al. "HIV Exposure and Neonatal Sepsis: A Descriptive Etiological Study." Open Forum Infectious Diseases 11, Supplement_3 (2024): S187—S192. https://doi.org/10.1093/ofid/ofae642.

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Abstract Background Low- and middle-income countries lack data on culture-confirmed sepsis in HIV-exposed infants, despite the reported heightened risk of infectious morbidity. This study describes culture-confirmed sepsis and antibiotic resistance patterns among HIV-exposed children in a large etiological cohort study in Kampala, Uganda. Methods This was a prospective birth cohort study based at 2 Ugandan sites, as part of the Progressing Group B Streptococcal Vaccines (PROGRESS) study. Any infant with risk factors, signs, or symptoms of infection presenting before 3 months of age had a blood
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Korkmaz, Ş. Gamze, and Gülseren Keskin. "Neuropsychıatrıc dısorders assocıated wıth chıldhood ımmunologıc dysfunctıon." Innowacje w Pielęgniarstwie 4, no. 8 (2023): 127–36. http://dx.doi.org/10.21784/iwp.2023.024.

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Introduction. These disease entities are known as pediatric neuropsychiatric syndromes because infectious pathogens other than streptococci have also been reported to be associated with neuropsychiatric symptoms. Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS).&#x0D; Aim. The aim of this study was to evaluate neuropsychiatric disorders associated with immunologic dysfunction in childhood.&#x0D; Overview. PANS/PANDAS refers to the acute and dramatic onset of a neuropsychiatric syndrome in
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Mazur, Elżbieta. "Management of acute streptococcal pharyngitis: still the subject of controversy." Open Medicine 8, no. 6 (2013): 713–19. http://dx.doi.org/10.2478/s11536-013-0216-z.

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AbstractAlthough most cases of acute pharyngitis are viral in origin, antibiotics are overused in its treatment. Streptococcus pyogenes (group A streptococcus, GAS), the principal bacterial pathogen of acute sore throat, is responsible for merely 5–30% of cases. Moreover, GAS pharyngitis is currently the only commonly occurring form of acute pharyngitis for which antibiotic therapy is definitely indicated. Therefore the differentiation between GAS pharyngitis and that of viral etiology is crucial. Accordingly, scientific societies as well as respected advisory bodies in Europe and North Americ
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47

Rakshana V, Saranya P, Jaya Shree S, et al. "Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS) Syndrome." Journal of Pharma Insights and Research 2, no. 5 (2024): 020–27. http://dx.doi.org/10.69613/h5p77g26.

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Often preceded by a streptococcal infection, pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections, or PANDAS, is an uncommon syndrome marked by the abrupt development of tic disorders or obsessive-compulsive disorder (OCD). It is thought that the infection generated an inflammatory reaction that resulted in brain inflammation and this disease. A multidisciplinary strategy combining medical practitioners, mental health specialists, and behavioural therapists is necessary for the effective management of PANDAS. Appropriate therapy and early diagnosis can assist
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Kovaleva, Yu S., and O. A. Kokina. "Polycomponent drugs in the treatment of intertriginous dermatosis." Meditsinskiy sovet = Medical Council, no. 13 (August 9, 2022): 60–65. http://dx.doi.org/10.21518/2079-701x-2022-16-13-60-65.

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The most common localization of dermatoses of combined etiology are intertriginous areas. In recent years, an increase in the number of patients suffering from dermatoses of combined etiology has been recorded. The reasons for this situation can be both irrational therapy and background comorbidities in the patient, as well as a number of anatomical and physiological prerequisites for the formation and maintenance of an inflammatory infectious process with localization, namely in the area of skin folds. The article describes in detail the anatomical and physiological features of these areas, t
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MIURA, Ernani, and Maria Cristina MARTIN. "Group B streptococcal neonatal infections in Rio Grande do Sul, Brazil." Revista do Instituto de Medicina Tropical de São Paulo 43, no. 5 (2001): 243–46. http://dx.doi.org/10.1590/s0036-46652001000500001.

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Group B Streptococcus is the most common pathogen found in neonatal sepsis in North America. OBJECTIVES: We describe 15 cases of neonatal infections by Group B Streptococcus (Streptococcus agalactiae) at a Neonatal Intensive Care Unit of a public and teaching hospital. METHODS: We conducted a study at Hospital de Clínicas de Porto Alegre, from January 1st, 1996 to June 30, 1999. Diagnosis of neonatal infection was established according to the findings of Group B Streptococcus in blood culture associated with alterations resembling sepsis on the basis of clinical picture and laboratory findings
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50

Vivar, Sussi, Jennifer E. Girotto, and Thomas S. Murray. "A Dual Case of Peritonitis and Central Nervous System Infection Caused by Nutritionally Variant Streptococcal Species." Case Reports in Infectious Diseases 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/6012964.

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Nutritional variant streptococci (NVS) are difficult to identify bacteria that can cause invasive infections such as endocarditis and meningitis. NVS as a cause of peritonitis has not been routinely described. This case of NVS as the etiology of peritonitis associated with previous neurosurgery and ventriculoperitoneal (VP) shunt revision demonstrates its potential role as a significant pathogen in patients with peritonitis and VP shunts. Therapy consists of vancomycin plus a second agent but since there are no standards for susceptibility testing, clinical response remains the standard for de
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