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Dissertations / Theses on the topic 'Streptococcus gordonii'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Christie, Julie. "Fibronectin-interacting proteins in Streptococcus gordonii." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324360.

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2

Macarthur, Deborah Jane. "Mapping The Proteome Of Streptococcus Gordonii." Thesis, The University of Sydney, 2005. http://hdl.handle.net/2123/5097.

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Streptococcus gordonii is a primary coloniser of the tooth surface where it efficiently ferments carbohydrates at pH levels above 6.0. By not being able to maintain the pH of dental plaque to a level required for enamel dissolution, the dominance of S. gordonii in dental plaque is considered a sign of a healthy oral cavity. However, upon entering the bloodstream and encountering a rise in pH, S. gordonii may become pathogenic, being one of the major causative organisms associated with infective endocarditis. Proteome analyses of S. gordonii grown at steady state in a chemostat allowed t

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3

Macarthur, Deborah Jane. "Mapping the proteome of Streptococcus gordonii." University of Sydney. Health Science, 2005. http://hdl.handle.net/2123/686.

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Streptococcus gordonii is a primary coloniser of the tooth surface where it efficiently ferments carbohydrates at pH levels above 6.0. By not being able to maintain the pH of dental plaque to a level required for enamel dissolution, the dominance of S. gordonii in dental plaque is considered a sign of a healthy oral cavity. However, upon entering the bloodstream and encountering a rise in pH, S. gordonii may become pathogenic, being one of the major causative organisms associated with infective endocarditis. Proteome analyses of S. gordonii grown at steady state in a chemostat allowed t

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4

Jack, Alison Alexandra. "Signalling interactions between Streptococcus gordonii and Candida albicans." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633446.

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Streptococcus gordonii is an early bacterial coloniser of the oral cavity and influences development of plaque biofilms. Interactions of Candida albicans, an opportunistic fungal pathogen, with S. gordonii are hypothesised to promote fungal carriage and persistence. Evidence suggests that signalling molecules produced by streptococci, including competence stimulating peptide (eSP) and autoinducer 2 (AI -2L affect C. albicans growth. However, less is understood about the molecular basis of these interactions.

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5

Forsgren, Nina. "Structural studies of the surface adhesin SspB from Streptococcus gordonii." Doctoral thesis, Umeå : Umeå universitet, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-32910.

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6

Ilias, Mohammad. "Family II soluble inorganic pyrophosphatases from 'Streptococcus gordonii' and 'Vibrio cholerae'." Thesis, University of Birmingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410862.

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7

Robinson, Jill Christie. "Impact of L-arginine on Streptococcus gordonii gene expression and biofilm formation." Thesis, University of Newcastle upon Tyne, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701159.

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Streptococcus gordonii is an oral commensal bacterium, and an early coloniser of the acquired salivary pellicle that coats tooth surfaces. As such, it is a key organism in the establishment of dental plaque biofilms. The amino acid L-arginine has been previously shown to play a role in biofilm formation in other oral species, and depletion of L-arginine has a significant impact upon S. gordonii growth and gene regulation. Three L-arginine-dependent transcription regulators have been identified in S. gordonii, but it is currently not clear how these co-ordinate to sense and respond to changes i

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8

O'Connell, Silverman Richard James. "Molecular basis of mixed-species biofilm formation between streptococcus gordonii and candida albicans." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529889.

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9

Higashi, Daniela. "Modulação do biofilme de Porphyromonas gingivalis pela associação com Streptococcus gordonii e com Prevotella intermedia." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-10042015-123236/.

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P. gingivalis é um dos principais patógenos da doença periodontal, é encontrado em biofilmes orais com S. gordonii e P. intermedia e em células endoteliais da artéria coronária in vivo. P. gingivalis necessita de ferro em seu metabolismo e pode usar certas proteínas do hospedeiro como fontes deste íon em ambientes limitantes. Assim, este estudo investigou o papel dos genes PGN0741/PG0637 (receptor dependente de TonB) e PGN0531/PG1380 (fvW) de P. gingivalis na formação de biofilme em diferentes concentrações de ferro, em biofilmes mistos com S. gordonii e P. intermedia, e na adesão e invasão de

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10

Nylander, Åsa, Gunnel Svensäter, Dilani B. Senadheera, Dennis G. Cvitkovitch, Julia R. Davies, and Karina Persson. "Structural and functional analysis of the N-terminal domain of the Streptococcus gordonii adhesin Sgo0707." Umeå universitet, Oral mikrobiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-71563.

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The commensal Streptococcus gordonii expresses numerous surface adhesins with which it interacts with other microorganisms, host cells and salivary proteins to initiate dental plaque formation. However, this Gram-positive bacterium can also spread to non-oral sites such as the heart valves and cause infective endocarditis. One of its surface adhesins, Sgo0707, is a large protein composed of a non-repetitive N-terminal region followed by several C-terminal repeat domains and a cell wall sorting motif. Here we present the crystal structure of the Sgo0707 N-terminal domains, refined to 2.1 Å reso

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11

Gholami, Samaneh. "Physicochemical and antigenic properties correlation in Streptococcus gordonii vaccine vectors and development of a Streptococcus pneumoniae intra-tracheal mouse model of pneumonia." Doctoral thesis, Università di Siena, 2023. https://hdl.handle.net/11365/1225314.

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In the present thesis, the correlation between the physicochemical and antigenic properties of different recombinant Streptococcus gordonii vaccine vectors was studied. Evaluation of vaccine efficacy, antigenicity and immugenicity is a crucial step in developing vaccines, thus investigating a simple method to analyze vaccine efficacy besides other methods could be a major part of developing bacterial vaccine vectors. To approach this, isoelectric point measurements and zeta-potential titration as well as antigenicity and immunogenicity of S.gordonii vaccine vectors (with fbpA, RPS, gtfg gene

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12

Morales, Castro Valentina Alejandra. "Recuento de Streptococcus sanguinis, Streptococcus gordonii y Streptococcus mutans en muestras de saliva y placa bacteriana supragingival de niños escolares de 6 y 7 años de edad con diferente actividad cariogénica." Tesis, Universidad de Chile, 2016. http://repositorio.uchile.cl/handle/2250/147239.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>La caries dental es un proceso localizado de origen multifactorial que se inicia luego de ocurrida la erupción dentaria, determinando el reblandecimiento del tejido duro del diente y que puede evolucionar hasta la formación de una cavidad. La cavidad oral contiene muchas bacterias, de las cuales son las acidogénicas las que están involucradas en el proceso carioso, a la par que también existen bacterias alcalogénicas contrarrestando esta acidogenicidad. El propósito de este trabajo es determinar la correlació

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13

Philosof, Bar. "A bacterium from the human microbiota as a vaccine vector. Efficient priming of the murine immune system by vaginal delivery of recombinant Streptococcus gordonii." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1216735.

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The ability to prime the immune system against an antigen, and to rapidly recall this response upon antigen reencounter is a fundamental characteristic of the adaptive immune response. The association of an antigen recognized by the immune system in a certain tissue, with the same antigen encountered at a later timepoint in a different tissue, is of primary importance to obtain a systemic and effective immune response and is the foundation behind the utilization of vaccines. The study of vaccine delivery platforms that may activate the immune system in such a manner is therefore of primary imp

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14

Vidyasanker, Radhika. "The rpsL gene and streptomycin resistance in Streptococcus gordonii and Streptococcus pyogenes." Thesis, 1999. http://hdl.handle.net/1957/33219.

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Streptomycin resistance in both gram-positive and gram-negative bacteria is usually caused by a single mutation in the rpsL gene. The rpsL gene encodes the S12 protein of the ribosomal complex. The rpsL genes of various bacteria have consensus regions in their sequences. Primers were designed from these consensus pockets and a fragment of the rpsL gene was sequenced from S. gordonii using PCR based methodologies. Using the Multiplex Restriction Sequence PCR(mRS PCR), which used the known primer at one end and a restriction site primer on the other, a gene walk was conducted. In streptomycin re

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15

VICKERMAN, MARY MARGARET. "ECOLOGICAL IMPLICATIONS OF GLUCOSYLTRANSFERASE PHASE VARIATION IN STREPTOCOCCUS GORDONII." 1991. http://books.google.com/books?id=fSxqAAAAMAAJ.

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16

Hulbah, Maram. "Development of An Antibiotic Marker-Free Gene Delivery System in Streptococcus gordonii." 2013. http://hdl.handle.net/10222/21770.

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Streptococcus gordonii, a commensal oral bacterium, is considered a good candidate to function as a live oral vaccine vector. The introduction of vaccine antigen genes into S. gordonii relies on the use of antibiotic resistance genes as selectable markers, which is undesirable. In this study, we used auxotrophic complementation (deletion of an essential gene from the chromosome and insertion into a plasmid) as a means to create an antibiotic marker-free gene delivery system in S. gordonii. S. gordonii ?thyA was created and complemented by an antibiotic marker-free expression plasmid containing

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17

Hsu, Jia-Chuan, and 許家銓. "Determination of groESL Gene Sequences of Streptococcus gordonii and Streptococcus oralis and Use as Targets for Species Identification." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/50398279022416237204.

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碩士<br>國立臺灣大學<br>醫事技術學研究所<br>87<br>The oral or viridans group streptococci form a significant part of the normal flora of the human oral cavity and are associated with several disease conditions including dental caries, infective endocarditis and septicemia as well as purulent infections. Currently the viridans group streptococci taxonomically could be divided into five major clusters which included at least 20 species. These are S. mutans group, S. mitis group, S. milleri group, S. salivarius group and S. bovis group. No single system of classification suffices for the identification of this h

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18

Wang, Kuei-Ling, and 王貴靈. "Molecular cloning and characterization of the sodA gene from Streptococcus gordonii ATCC 10588." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/55669111834158359944.

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碩士<br>國立臺灣大學<br>微生物學研究所<br>89<br>Streptococcus gordonii is a species of the viridans group streptococci, and is the major pathogen of dental caries. Superoxide dismutase, SOD, is an antioxidant enzyme, which scavenges O2-to protect cells from damage. In this study, we characterized the SOD of S. gordonii as an MnSOD by H2O2 and diethyldithiocarbamate inhibition test. Furthermore, we also found that the SOD has activity as a cambialistic enzyme, which can accept either iron or manganese as the cofactor to present enzyme activity. The activity of manganese —containing SOD was higher than that ir

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19

Cyue, Ming Hong, and 闕銘宏. "Identification and functional analysis of Streptococcus gordonii CH1 TCS-08 and TCS-13." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/72072210276417648631.

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碩士<br>長庚大學<br>生物醫學研究所<br>99<br>Streptococcus gordonii CH1 is one of the early colonizers of the dental plaque. The two-component system (TCS) is the major signal transduction system in bacteria. Since pH alteration is a frequent event occurring in the oral cavity, this study aims to identify TCSs that are potentially involved in the pH signaling in S. gordonii. To monitor the effects of mutations in TCS in pH signaling, the promoterless chloramphenicol acetyltransferase gene (cat) was fused with the pH-sensitive urease promoter (pureI) of Streptococcus salivarius and integrated into the gtf

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20

Goldstein, Jason Marc. "The isolation, characterization and cloning of three novel peptidases from streptococcus gordonii : their potential roles in subacute bacterial endocarditis." 2001. http://purl.galileo.usg.edu/uga%5Fetd/goldstein%5Fjason%5Fm%5F200112%5Fphd.

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21

Gomes, Veronique de Sousa. "Microflora oral e risco de doenças orais numa amostra de crianças portuguesas." Master's thesis, 2014. http://hdl.handle.net/10400.14/15289.

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Introdução: A saúde oral é parte da saúde geral, bem-estar e qualidade de vida. Deste modo, o conhecimento da prevalência da cárie dentária na população infantil leva-nos a adotar, cada vez mais, um conjunto de medidas de prevenção, permitindo o controlo, não só dos fatores etiológicos da doença, mas também a diminuição da sua incidência. O conhecimento da microflora oral e a exploração do potencial alcalinizante de algumas bactérias orais, são uma estratégia promissora no que diz respeito à prevenção da cárie dentária. Objetivos: Este estudo visa avaliar, os comportamentos e o estado de saúd

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22

Zheng, Cunge. "The effect of cigarette smoking on the virulence of streptococcus mutans caries and cardiovascular diseases-epidemiological analysis and in vitro studies." Thesis, 2010. http://hdl.handle.net/1805/2311.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>The impact of tobacco smoking on human health is well documented. The influence of smoking on tooth loss and cardiovascular diseases was investigated in the current study via both epidemiology and in vitro studies. From analyzing the 2006 Behavioral Risk Factor Surveillance System (2006 BRFSS) database, we confirmed that smoking was significantly associated with the number of teeth lost in a dose-dependent manner and smoking cessation reduced the risk when compared to those subjects continuing to smoke. In addition, the virulenc

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