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Dissertations / Theses on the topic 'Streptococcus pneumonias'

Author: Grafiati

Published: 10 December 2022

Last updated: 31 July 2025

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1

Yoshioka, Cristina Ryoka Miyao. "Estudo das pneumonias causadas por Streptococcus pneumoniae em crianças internadas na enfermaria de pediatria do Hospital Universitário da Universidade de São Paulo." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-07122009-185246/.

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Introdução: Atualmente a incidência anual de pneumonia adquirida na comunidade nos países em desenvolvimento é de 150,7 milhões de casos entre crianças menores de 5 anos de idade , dos quais 11 a 20 milhões (7-13%) necessitam de internação hospitalar devido à gravidade. O tratamento geralmente é empírico mas o Streptococcus pneumoniae é o principal agente etiológico bacteriano.É necessário manter monitoramento dos sorotipos e padrão de resistência para melhor orientação terapêutica. Metodologia: Estudo de coorte retrospectivo com inclusão de 107 crianças com diagnóstico clínico e radiológico d

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2

Bazaz, Rohit. "The effect of Streptococcus pneumoniae pneumonia on atherosclerosis." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/16897/.

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3

Koppe, Uwe Moritz Eberhard. "Role of type I interferons in Streptococcus pneumoniae pneumonia." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16532.

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Streptococcus pneumoniae ist die häufigste Ursache für ambulant erworbene Pneumonien weltweit. Daher müssen die Wirts-Pathogen-Interaktionen erforscht werden, um neue Therapiestrategien zu entwickeln. In dieser Studie habe ich 1. den Typ I Interferon (IFN)-stimulierenden Signalweg des angeborenen Immunsystems in Pneumokokken-infizierten Wirtszellen sowie 2. dessen Bedeutung in der Pneumokokkenpneumonie untersucht. Humane und murine Makrophagen, aber nicht alveolare Epithelzellen, produzierten Typ I IFNs nach Infektion mit S. pneumoniae. Dieses war abhängig vom Virulenzfaktor Pneumolysin und e

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4

McNamee, Lynnelle Ann. "Effects of a primary influenza infection on susceptibility to a secondary Streptococcus pneumoniae infection." Diss., Montana State University, 2006. http://etd.lib.montana.edu/etd/2006/mcnamee/McNameeL1206.pdf.

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5

Silva, Júnior Jailton de Azevedo. "Estudo da colonização nasofaringeana por Streptococcus pneumoniae em crianças com suspeita clínica de pneumonia." reponame:Repositório Institucional da FIOCRUZ, 2011. https://www.arca.fiocruz.br/handle/icict/4220.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2012-07-19T21:35:50Z No. of bitstreams: 1 Jailton de Azevedo Silva Junior Estudo da colonização....pdf: 1101716 bytes, checksum: 049972199c76bb97406fc006c2ba9c27 (MD5)<br>Made available in DSpace on 2012-07-19T21:35:50Z (GMT). No. of bitstreams: 1 Jailton de Azevedo Silva Junior Estudo da colonização....pdf: 1101716 bytes, checksum: 049972199c76bb97406fc006c2ba9c27 (MD5) Previous issue date: 2011<br>Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil<br>Streptococcus pneumoniae constitui um

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6

Scholtz, Janet. "The serotypes and antimicrobial susceptibility patterns of streptococcus pneumoniae in the Cape Peninsula." Thesis, Cape Technikon, 2000. http://hdl.handle.net/20.500.11838/1464.

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Thesis (Masters Diploma(Technology))--Cape Technikon, Cape Town, 2000<br>Streptococcus pneumoniae (S.pneumoniae) infections are an important cause of morbidity and mortality in adults and children worldwide. Mortality rates are highest amongst the very young and the elderly. Streptococcus pneumoniae is the most common form of community acquired bacterial pneumonia. Other diseases commonly caused by Streptococcus pneumoniae include meningitis, pericarditis, bacteraemia and septicaemia. Penicillin is today still consid3red the drug of choice when treating pneumococcal infections. The

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7

Abdeldaim, Guma M. K. "PCR detection of Streptococcus pneumoniae and Haemophilus influenzae in pneumonia patients." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl.[distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107931.

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8

Ekdahl, Karl. "Immunological aspects on pneumococcal infections with special reference to bacteremic pneumococcal infections and recurrent pneumonia /." Lund : Dept. of Infectious Diseases, University of Lund, 1995. http://catalog.hathitrust.org/api/volumes/oclc/39177549.html.

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9

Machado, Lais Del Prá Netto. "Pneumonia bacteriana adquirida na comunidade: avaliação clínico-epidemiológica e padronização de métodos moleculares para detecção de Mycoplasma pneumoniae, Haemophilus influenzae e Streptococcus pneumoniae." reponame:Repositório Institucional da UFSC, 2015. https://repositorio.ufsc.br/xmlui/handle/123456789/158899.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.<br>Made available in DSpace on 2016-02-09T03:17:04Z (GMT). No. of bitstreams: 1 336847.pdf: 2261623 bytes, checksum: 5220583fc8a657b02f17b72e42ab63bc (MD5) Previous issue date: 2015<br>A pneumonia pode ser causada por diversos microrganismos e classificada de forma abrangente, havendo poucos e frágeis estudos clínicos e epidemiológicos sobre pneumonias adquiridas na comunidade (PACs). Os patógenos mais frequentes nas PACs são Streptococcus

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10

Piroth, Lionel. "Apports d'un modèle de pneumonie expérimentale bactériémique à streptococcus pneumoniae de sensibilité diminuée à la pénicilline dans la prise en charge des pneumonies humaines." Dijon, 2001. http://www.theses.fr/2001DIJOMU02.

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Strpetococcus pneumoniae est l'un des pathogenes les plus frequemment responsables de pneumonies bacteriemiques, avec une morbidite et une mortalite consequentes. L'incidence des souches de s. Pneumoniae de sensibilite diminuee a la penicilline et a d'autres antibiotiques est en constante augmentation. Ces donnees et les problemes therapeutiques inherents soulignent l'importance d'une meilleure connaissance des relations hote-pathogene-antibiotique, que seuls les modeles experimentaux permettent d'approfondir significativement. Nous avons pu developper un modele reproductible et simple de pneu

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11

CARRARO, MONICA. "Identification of infection biomarkers in a murine model of pneumonia by Streptococcus pneumoniae." Doctoral thesis, Università di Siena, 2018. http://hdl.handle.net/11365/1037742.

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Streptococcus pneumoniae infections remain a public health problem despite the availability of vaccines. In order to study alternative preventive strategies it is essential to have a reliable animal model of the infection. To date, the majority of vaccine efficacy evaluation studies still rely on direct read-outs such as the survival rate after challenge and the CFU counts in blood and in the lungs. A murine model of lung infection was developed in which animal death was not the endpoint: clinical parameters, cellular lung infiltrate and systemic immune response were evaluated in (i) infected

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Leite, Ilaiáli Souza. "Inativação de Streptococcus pneumoniae por terapia fotodinâmica infravermelha com indocianina verde e sua interação com macrófagos RAW 264.7." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-17092015-110348/.

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As infecções do trato respiratório inferior lideram entre as principais causas de morbidade e mortalidade no mundo. Um dos grandes problemas associados ao tratamento das infecções do sistema respiratório, como as pneumonias, advém da crescente resistência aos mais modernos antibióticos adquirida pelos microrganismos. A terapia fotodinâmica, uma técnica baseada na interação da luz com uma substância fotoativa para causar dano oxidativo a células, tem se destacado como uma interessante alternativa para diversas doenças como diferentes tipos de câncer e infecções. Neste trabalho foi realizada, co

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13

Domingues, Carla Magda Allan Santos. "Avaliação da efetividade da vacina antipneumocócica 10 valente na redução da doença pneumocócica invasiva em crianças brasileiras : estudo caso controle multicêntrico." reponame:Repositório Institucional da UnB, 2014. http://repositorio.unb.br/handle/10482/18910.

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Tese (doutorado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-graduação em Medicina Tropical, 2014.<br>Submitted by Fernanda Percia França (fernandafranca@bce.unb.br) on 2015-12-04T11:40:13Z No. of bitstreams: 1 2014_CarlaMagdaAllanSantosDomingues.pdf: 9749751 bytes, checksum: 674ee7ccb659f8eb05072d9d7824b080 (MD5)<br>Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2015-12-11T14:39:55Z (GMT) No. of bitstreams: 1 2014_CarlaMagdaAllanSantosDomingues.pdf: 9749751 bytes, checksum: 674ee7ccb659f8eb05072d9d7824b080 (MD5)<br>Made availa

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Camargo, Dhian Renato Almeida. "Método, software e banco de dados para sorotipagem molecular de Streptococcus pneumoniae visando o monitoramento da eficácia do programa de vacinação no Brasil." s.n, 2014. https://www.arca.fiocruz.br/handle/icict/9937.

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Submitted by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-09T14:26:07Z No. of bitstreams: 1 Dissertacao_DhianRenatoAlmeidaCamargo.pdf: 3559105 bytes, checksum: 559d79208eea1b927b5dfdc61f96fdc8 (MD5)<br>Approved for entry into archive by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-09T14:26:15Z (GMT) No. of bitstreams: 1 Dissertacao_DhianRenatoAlmeidaCamargo.pdf: 3559105 bytes, checksum: 559d79208eea1b927b5dfdc61f96fdc8 (MD5)<br>Approved for entry into archive by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-09T14:26:27Z (GMT) No. of bitstreams: 1 Dissertacao_DhianRenatoAlmeidaCamarg

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Oliveira, Nayara Santos de. "Streptococcus pneumoniae: sensibilidade a antimicrobianos e detecção de genes de resistência em isolados de crianças com pneumonia adquirida na comunidade em Fortaleza, Ceará." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/17898.

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OLIVEIRA, N. S. Streptococcus pneumoniae: sensibilidade a antimicrobianos e detecção de genes de resistência em isolados de crianças com pneumonia adquirida na comunidade em Fortaleza, Ceará. 2013. 83 f. Dissertação (Mestrado em Microbiologia Médica) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2013.<br>Submitted by Erika Fernandes (erikaleitefernandes@gmail.com) on 2016-06-23T12:51:16Z No. of bitstreams: 1 2013_dis_nsoliveira.pdf: 1681873 bytes, checksum: c62b8c7f03d7d8081b4975a923cd4dae (MD5)<br>Approved for entry into archive by Erika Fernandes (erikaleitefernandes@gma

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Parameswar, Archana R. "Towards development of a fully synthetic conjugate vaccine investigation of structural analogs of Streptococcus pneumoniae serogroup 6 /." Diss., St. Louis, Mo. : University of Missouri--St. Louis, 2008. http://etd.umsl.edu/r3161.

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17

Bracht, Dagmar. "Proteomanalyse von Streptococcus pneumoniae." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=977729931.

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18

Magdelaine, François. "Etude de l'activité bactéricide de cinq associations d'antibiotiques sur cinq souches de "S. Pneumoniae" en vue d'une application thérapeutique dans le traitement des méningites à pneumocoque résistant à la péniciline G." Paris 5, 1993. http://www.theses.fr/1993PA05P061.

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19

Bedos, Jean-Pierre. "Evaluation pharmacodynamique de l'activite des fluoroquinolones dans des modeles murins de pneumonies experimentales a streptococcus pneumoniae." Paris 7, 1997. http://www.theses.fr/1997PA077175.

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Streptococcus pneumoniae est la bacterie principale des pneumonies communautaires. L'apparition de souches resistantes en particulier aux betalactamines souleve le probleme d'alternatives therapeutiques. Notre but a ete de fournir des donnees experimentales rationnelles, comparatives et explicatives de l'activite des nouvelles fluoroquinolones dans le traitement d'infection pulmonaire a s. Pneumoniae sensibles ou de moindre sensibilite a la penicilline. Le choix de modeles de pneumonies murines reproductibles a permis en jouant sur la virulence des souches de pneumocoques, la nature genetique

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20

Webb, Silky Fanyelle. "Hospitalizations associated with pneumococcal infection within the Medicare population among vaccinated and non-vaccinated patients." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0002032.

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21

Champagne, Marie-Eve. "Ré-infections avec Streptococcus pneumoniae : effet sur les réponses immunes innée et acquise lors d'une pneumonie à pneumocoque." Master's thesis, Université Laval, 2007. http://hdl.handle.net/20.500.11794/19368.

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22

Burman, Lars Å. "Streptococcus pneumoniae : epidemiological, clinical and serological studies." Doctoral thesis, Umeå universitet, Infektionssjukdomar, 1993. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-102563.

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A retrospective study of invasive pneumococcal disease in patients from Greater Göteborg in 1964- 1980 identified 125 cases of meningitis, 305 of pneumonia, 61 of septicemia with unknown focus, and 17 with other manifestations, all verified by cultures from normally sterile body fluids. The incidence was several times higher in infants and in the elderly than in any other age-group. A wide variety of underlying conditions were present in 23% of the infants, 34% of the children, and 81% of the adults. In adults alcoholism was known in one third of the cases. The case fatality rate was 24% among

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23

Gholami, Samaneh. "Physicochemical and antigenic properties correlation in Streptococcus gordonii vaccine vectors and development of a Streptococcus pneumoniae intra-tracheal mouse model of pneumonia." Doctoral thesis, Università di Siena, 2023. https://hdl.handle.net/11365/1225314.

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In the present thesis, the correlation between the physicochemical and antigenic properties of different recombinant Streptococcus gordonii vaccine vectors was studied. Evaluation of vaccine efficacy, antigenicity and immugenicity is a crucial step in developing vaccines, thus investigating a simple method to analyze vaccine efficacy besides other methods could be a major part of developing bacterial vaccine vectors. To approach this, isoelectric point measurements and zeta-potential titration as well as antigenicity and immunogenicity of S.gordonii vaccine vectors (with fbpA, RPS, gtfg gene

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24

Fillion, Isabelle. "La cinétique des chimiokines et rôle de MCP-1 lors d'une pneumonie à Streptococcus pneumoniae." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0020/MQ55852.pdf.

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Vallée, Éric. "Streptococcus pneumoniae et fluoroquinolones : évaluation de l'activité antipneumococcique dans la pneumonie expérimentle de la souris." Université de Paris-Sud. Faculté de pharmacie (Châtenay-Malabry, Hauts-de-Seine), 1992. http://www.theses.fr/1992PA114821.

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Silva, Sandra Rodrigues da. "Análise do impacto na redução de pneumonia adquirida na comunidade em crianças após a introdução da vacina antipneumocócica 10-valente no Programa Nacional de Imunização." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/17/17139/tde-30062015-155505/.

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O Streptococcus pneumoniae (pneumococo) constitui um dos mais importantes patógenos bacterianos do trato respiratório, podendo causar infecções invasivas e não invasivas, levando a altas taxas de morbimortalidade, particularmente em crianças menores de cinco anos de idade. A bactéria ganha acesso ao hospedeiro através da colonização da nasofaringe, que representa um importante reservatório para a transmissão deste patógeno na comunidade, contribuindo para a disseminação horizontal de pneumococo entre os indivíduos de uma população. As doenças respiratórias causadas por pneumococo constituem em

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27

Koo, Kun, and 古軍. "Vancomycin tolerance in streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31970588.

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Wyres, Kelly L. "Genome evolution in Streptococcus pneumoniae." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:985b1fc6-c1a9-41b3-a20a-1735329d962b.

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Streptococcus pneumoniae (the pneumococcus) is a bacterial pathogen responsible for >1.6 million annual deaths globally. Pneumococcal penicillin-resistance is conferred by acquisition of ‘altered’ penicillin-binding protein (pbp) genes. The first penicillin-nonsusceptible pneumococci were identified in the late 1960s. Global pneumococcal penicillin-nonsusceptibility rates rapidly increased in the 1980s/90s. Since 2000, protein-conjugate vaccines, targeting 7, 10 or 13 of the ≥94 different pneumococcal capsule types (serotypes), have been introduced in many countries. Following vaccine implemen

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Rudmann, Emily. "Parsing the Streptococcus pneumoniae virulome." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:108795.

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Thesis advisor: Tim van Opijnen<br>Streptococcus pneumoniae is a prominent gram-positive commensal and opportunistic pathogen which possesses a large pan-genome. Significant strain-to-strain variability in genomic content drives the use of varied pathways to perform similar processes between strains. Considering this variation, we employ a set of 36 strains, representative of 78% of total pan-genome diversity, with which to perform functional studies. We previously determined the set of genes required by 22 of the 36 strains to maintain successful infection in a host, or the virulome. In this

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Koo, Kun. "Vancomycin tolerance in streptococcus pneumoniae." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25139216.

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Alghofaili, Fayez Abdullah. "Streptococcus pneumoniae-stress hormone interactions." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/41267.

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Streptococcus pneumoniae is one of the most important bacterial pathogens of humans causing a wide range of mild to life-threating diseases. It is also a commensal microorganism in the nasopharynx of up to 60% of people. Fundamental aspects of its ability for transition from colonisation to an infectious state as well as how bacterial-host interactions influence this process are largely unknown. In the field of microbial endocrinology, it has been well established in mainly Gram-negative bacteria that stress hormones such as norepinephrine epinephrine and dopamine play an essential role in det

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Shriner, Anne K. "Analysis of the Human Variable Gene Repertoire in Response to Pneumococcal Polysaccharides." University of Toledo Health Science Campus / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=mco1174573682.

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Martins, João Paulo. "Estratégias para otimizar o acesso à vacina pneumocócica polissacarídica 23-valente junto à população de adultos com indicação clínica no SUS." Botucatu, 2019. http://hdl.handle.net/11449/183280.

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Orientador: Edison Iglesias de Oliveira Vidal<br>Resumo: Introdução: O Streptococcus Pneumoniae é o agente infeccioso mais frequentemente associado à ocorrência de pneumonia bacteriana e a vacinação é considerada a principal estratégia para a prevenção dessa doença. De acordo com o Programa Nacional de Imunização (PNI) a vacina pneumocócica polissacarídica 23-valente (Pn23) não faz parte do calendário básico de vacinação e deve ser dispensada a indivíduos a partir de 2 anos de idade desde que portadores de um conjunto de doenças e condições de alto risco para infecções pneumocócicas. A forma d

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Skull, Susan. "Effectiveness of influenza and pneumococcal vaccination against hospitalisation for community-acquired pneumonia among persons >65 years /." Connect to thesis, 2007. http://repository.unimelb.edu.au/10187/1998.

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Although there are well-documented benefits from influenza vaccine and 23-valent pneumococcal polysaccharide vaccine (23vPPV) against invasive pneumococcal disease and laboratory confirmed influenza, their effectiveness against pneumonia remains controversial for community-based persons aged >=65years. At the time of this research, within Australia, only the government of Victoria publicly funded these vaccines for elderly persons. With continued growth of the elderly population, the subsequent adoption of an Australia-wide program, and increasing uptake of similar programs in other countries,

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Owugha, J. T. "New vaccines against pneumonia : investigating protein-specific immune responses to Streptococcus pneumoniae using Experimental Human Pneumococcal Carriage." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3012998/.

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Infections caused by Streptococcus pneumoniae are a major cause of morbidity and mortality globally: S. pneumoniae is the primary bacterial agent of pneumonia, the leading cause of death in children under 5 years of age and a major cause of invasive disease in the elderly. Currently licensed vaccination strategies target pneumococcal capsular polysaccharides of which there are 94 known types (serotypes). Antibodies against vaccine serotypes effectively protect against invasive pneumococcal disease, but less so against mucosal infections including pneumonia. New vaccine development efforts aim

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Le, Thomas Isabelle. "Histoire naturelle de la colonisation nasopharyngée par Streptococcus pneumoniae chez l'enfant vivant en crèche fermée." Paris 5, 1998. http://www.theses.fr/1998PA05P205.

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Floc'h, Erwan. "Contribution à l'étude de l'épidémiologie de Streptococcus pneumoniae résistant aux bêta-lactamines." Paris 5, 1998. http://www.theses.fr/1998PA05P010.

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McNamara, Tracy Renee. "Chlamydia pneumoniae and airways inflammation : an investigation of the host cell-pathogen relationship /." Title page, table of contents and abstract only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phm4791.pdf.

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Fernebro, Jenny. "Genetic approaches towards understanding pneumococcal virulence and biology /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-403-7/.

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Miotto, Fabiane. "Estudo da resistência do streptococcus pneumoniae à penicilina em pneumopatias infecciosas nas cidades de Porto Alegre e Caxias do Sul (RS - Brasil)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2001. http://hdl.handle.net/10183/5465.

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A resistência aos antibióticos dos patógenos mais comuns do trato respiratório está aumentando mundialmente. Recentemente, Streptococcus pneumoniae resistente à penicilina tem sido isolado em diversos países, e a freqüência dessas cepas tem elevado de modo alarmante. O aumento da resistência, com conseqüentes implicações terapêuticas, tem levado a uma reavaliação do uso dos antibióticos ß-lactâmicos para o tratamento de infecções pneumocócicas. No presente trabalho, um total de 107 amostras de Streptococcus pneumoniae, obtidas de materiais provenientes de pacientes adultos ambulatoriais e hosp

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Vasconcellos, Ângela Gomes de. "Perfil de citocinas em crianças com pneumonia adquirida na comunidade." de Medicina, 2015. http://repositorio.ufba.br/ri/handle/ri/18654.

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Morona, Judy Kay. "Characterisation of the capsular polysaccharide biosynthesis loci of streptococcus pneumoniae serogroup 19 /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phm8678.pdf.

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Pratt, Stephanie Ann. "Immunoglobulin A1 protease of Streptococcus pneumoniae." Thesis, University of Leicester, 1988. http://hdl.handle.net/2381/35410.

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The aim of this project was to examine the Streptococcal IgA1 proteases, with particular interest on the Streptococcus pneumoniae enzyme. IgA1 protease of S. pneumoniae was identified and characterised. A non-reducing polyacrylamide gel system was employed to screen clinical isolates for IgA1 protease activity. Of 187 isolates tested 18% were found to be IgA1 protease negative, there was no correlation with the site of isolation of the organism and its ability to produce the enzyme. Attempts were made to clone the pneumococcal IgA1 protease gene using the cosmid pEMBLcos4, the plasmid vector p

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Ho, Pak-leung, and 何柏良. "Emerging antimicrobial resistance in Streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41290999.

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Ibrahim, Yasser Musa. "Stress response proteins in Streptococcus pneumoniae." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412962.

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Ouennane, Siham. "Interactions phage-hôte chez Streptococcus pneumoniae." Doctoral thesis, Université Laval, 2017. http://hdl.handle.net/20.500.11794/27790.

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Streptococcus pneumoniae est une bactérie à la fois commensale et pathogène opportuniste chez l’humain. Elle est responsable de nombreuses infections telles que la pneumonie, la méningite, l’otite moyenne et la sinusite. En maladie infectieuse, S. pneumoniae occupe une place importante en tant que l’une des principales causes de morbidité et de mortalité dans le monde. Elle est dotée de plusieurs capacités fascinantes, comme la compétence naturelle pour l’aider à résister aux antibiotiques et la grande diversité des sérotypes capsulaires pour contourner la vaccination. Puisque la résistance au

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Carvalho, Ricardo Jorge da Silva. "Revisiting molecular diagnostics of Streptococcus pneumoniae." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/16115.

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Mestrado em Biologia Molecular e Celular<br>Streptococcus pneumoniae is a human pathobiont that colonizes the nasopharynx. S. pneumoniae is responsible for causing non-invasive and invasive disease such as otitis, pneumonia, meningitis, and sepsis, being a leading cause of infectious diseases worldwide. Due to similarities with closely related species sharing the same niche, it may be a challenge to correctly distinguish S. pneumoniae from its relatives when using only non-culture based methods such as real time PCR (qPCR). In 2007, a molecular method targeting the major autolysin (lytA) of S.

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Chewapreecha, Kamolchanok. "Evolution of Streptococcus pneumoniae during carriage." Thesis, University of Cambridge, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708595.

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Ho, Pak-leung. "Emerging antimicrobial resistance in Streptococcus pneumoniae." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41290999.

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Croisier, Delphine. "Pharmacodynamie des fluoroquinolones dans la pneumonie expérimentale à streptococcus pneumoniae : étude de la fenêtre de selection des mutations." Dijon, 2005. http://www.theses.fr/2005DIJOMU02.

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L'efficacité de 3 nouvelles fluoroquinolones (lévofloxacine, gatifloxacine, moxifloxacine) a été évaluée dans un modèle expérimental de pneumonie à pneumocoque avec traitement humanisé. In vivo, ces 3 FQ sont très actives sur la souche sauvage. Toutefois, lorsque la souche porte une mutation parC, un traitement standard par FQ s'associe à un échec microbiologique du fait de l'émergence de mutants résistants (MR). Si les critères pharmacodynamiques incluant la CMI (AUC/CMI, Cmax/CMI) ne constituent pas de bons marqueurs de survenue de ces MR, les paramètres intégrant la fenêtre de sélection des

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