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Relevant bibliographies by topics / Streptomyces; Antibiotics

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Academic literature on the topic 'Streptomyces; Antibiotics'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Streptomyces; Antibiotics"

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Efimenko, Tatiana A., Alla A. Glukhova, Mariia V. Demiankova, Yuliya V. Boykova, Natalia D. Malkina, Irina G. Sumarukova, Byazilya F. Vasilieva, et al. "Antimicrobial Activity of Microorganisms Isolated from Ant Nests of Lasius niger." Life 10, no. 6 (June 22, 2020): 91. http://dx.doi.org/10.3390/life10060091.

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In this study, the microbial communities of two nests of black garden ants (Lasius niger) in the hollows of stem branches of old apple trees were found to have similar species compositions: each community contained representatives of three species from the Bacillaceae family and one species of actinomycetes from the genus Streptomyces. In total, four types of bacilli and two actinomycetes were isolated. Actinomycetes were identified as Streptomyces antibioticus-like and Streptomyces sp. None of the bacilli had antibiotic activity, whereas both streptomycetes produced antibiotics that inhibited the growth of Gram-positive bacteria in vitro, including isolates from their community. Antibiotic compounds of S. antibioticus-like strain INA 01148 (Institute of New Antibiotics) were identified as actinomycin D and its closest homologue, actinomycin A. Actinomycins presumably change the microbial community of the ant nest substrate as they act against Gram-positive bacteria and against fungi and Gram-negative bacteria. The antibiotic activity of the isolated Streptomyces sp. INA 01156 is of interest, since the substances produced by this strain inhibit the growth of drug-resistant bacteria, including methicillin-resistant Staphylococcus aureus INA 00761 (MRSA) and vancomycin-resistant strain Leuconostoc mesenteroides VKPM B-4177 (VR) (VKPM–National Collection of Industrial Microorganisms (Russian acronym)).

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David, Michelle, Clara Lejeune, Sonia Abreu, Annabelle Thibessard, Pierre Leblond, Pierre Chaminade, and Marie-Joelle Virolle. "Negative Correlation between Lipid Content and Antibiotic Activity in Streptomyces: General Rule and Exceptions." Antibiotics 9, no. 6 (May 26, 2020): 280. http://dx.doi.org/10.3390/antibiotics9060280.

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Streptomycetes are well known antibiotic producers and are among the rare prokaryotes able to store carbon as lipids. Previous comparative studies of the weak antibiotic producer Streptomyces lividans with its ppk mutant and with Streptomyces coelicolor, which both produce antibiotics, suggested the existence of a negative correlation between total lipid content and the ability to produce antibiotics. To determine whether such a negative correlation can be generalized to other Streptomyces species, fifty-four strains were picked randomly and grown on modified R2YE medium, limited in phosphate, with glucose or glycerol as the main carbon source. The total lipid content and antibiotic activity against Micrococcus luteus were assessed for each strain. This study revealed that the ability to accumulate lipids was not evenly distributed among strains and that glycerol was more lipogenic than glucose and had a negative impact on antibiotic biosynthesis. Furthermore, a statistically significant negative Pearson correlation between lipid content and antibiotic activity could be established for most strains, but a few strains escape this general law. These exceptions are likely due to limits and biases linked to the type of test used to determine antibiotic activity, which relies exclusively on Micrococcus luteus sensitivity. They are characterized either by high lipid content and high antibiotic activity or by low lipid content and undetectable antibiotic activity against Micrococcus luteus. Lastly, the comparative genomic analysis of two strains with contrasting lipid content, and both named Streptomyces antibioticus (DSM 41,481 and DSM 40,868, which we found to be phylogenetically related to Streptomyces lavenduligriseus), indicated that some genetic differences in various pathways related to the generation/consumption of acetylCoA could be responsible for such a difference.

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Taher, Nehad A., Ansam S. Husen, Zahraa Sh Mahmood, and Ghanyia J. Shanior. "A Study on Actinorhodin-like Substance Production by Streptomyces IQ45." Al-Mustansiriyah Journal of Science 31, no. 3 (August 20, 2020): 6. http://dx.doi.org/10.23851/mjs.v31i3.93.

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Production of pH-pigment (actinorhodin – like substance) was ascertained from ten Streptomyses isolates. Streptomyses IQ45 isolate was only isolated which produced pH- sensitive pigment. The production of pH-sensitive pigment was detected by fuming over ammonia. After extraction of this antibiotic, a number of physiocochemical characterizations were carried out which involved (IR, UV, MP, CHN-analysis, and solubility test). Indicated that this antibiotic is an actinorhodin-like substance. TLC of the extracted substance showed a single spot with Rf value equivalent to (0.26) which was close to that of actinorhodin.These antibiotics showed inhibitory activity against Staphylococcus aureus similar to that of actinorhodin produced by Streptomyces coelicolor A3 (2). The productivity of this antibiotics was (45 mg/L) at pH 8.5 and (40 mg/L) at pH 7 from the mycelial mat and (10 mg/L) when extracted from the liquid medium at pH7.

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Okamoto-Hosoya, Yoshiko, Susumu Okamoto, and Kozo Ochi. "Development of Antibiotic-Overproducing Strains by Site-Directed Mutagenesis of the rpsL Gene in Streptomyces lividans." Applied and Environmental Microbiology 69, no. 7 (July 2003): 4256–59. http://dx.doi.org/10.1128/aem.69.7.4256-4259.2003.

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ABSTRACT Certain rpsL (which encodes the ribosomal protein S12) mutations that confer resistance to streptomycin markedly activate the production of antibiotics in Streptomyces spp. These rpsL mutations are known to be located in the two conserved regions within the S12 protein. To understand the roles of these two regions in the activation of silent genes, we used site-directed mutagenesis to generate eight novel mutations in addition to an already known (K88E) mutation that is capable of activating antibiotic production in Streptomyces lividans. Of these mutants, two (L90K and R94G) activated antibiotic production much more than the K88E mutant. Neither the L90K nor the R94G mutation conferred an increase in the level of resistance to streptomycin and paromomycin. Our results demonstrate the efficacy of the site-directed mutagenesis technique for strain improvement.

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Loboda, M. I., L. O. Biliavska, and G. O. Iutynska. "Biosynthesis of Polyene Antibiotics and Phytohormones by Streptomyces netropsis IMV Ac-5025 under the Action of Exogenous Isopentenyladenosine." Mikrobiolohichnyi Zhurnal 83, no. 2 (April 17, 2021): 32–41. http://dx.doi.org/10.15407/microbiolj83.02.032.

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Streptomyces are active producers of a wide range of metabolites with multidirectional biological activity. Streptomyces netropsis IMV Ac-5025 synthesizes a polyene antibiotic complex in which two fractions were identified: heptaene candidine and a new tetraene fraction of unknown structure. The influence of secondary metabolites on the polyene antibiotics biosynthesis by soil streptomycetes is insufficiently explored. The aim of this work was to research the effect of exogenous isopentenyladenosine on the biosynthesis of polyene antibiotics and cytokinins by S. netropsis IMV Ac-5025. Methods. The strain was cultured in submerged cultivation condition in organic (soy) and synthetic (starch-ammonia) liquid nutrient media. The studies of biomass accumulation (gravimetric method), glucose consumption (glucose oxidase method), pH changes of culture media (ionometric method), biosynthesis of polyene antibiotics, and phytohormones (quantitative and qualitative thin layer chromatography spectrodensitometric method) were conducted. The results were analyzed in Statisticav.6.0 program. Results. It was found that polyene antibiotics are synthesized after the first day of cultivation, which indicates their role in the metabolism of streptomycetes. The biggest amount of the polyene antibiotics was accumulated in the stationary phase of producer growth (on the 7th day). It was found the decrease of polyene antibiotics and cytokinins accumulation in the producer’s biomass with the increase of exogenous cytokinin concentration from 25 ng/mL to 500 ng/mL. The bioproduction of the tetraene fraction was suppressed to a greater extent – up to 92% in the synthetic and up to 23% – in organic nutrient media. However, the amount of producer biomass increased under the action of the exogenous substance that confirming the positive effect of exogenous cytokinin on cell division of S. netropsis IMV Ac-5025. Exogenous isopentenyladenosine reduced the accumulation of endogenous cytokinins in streptomycetes biomass. Conclusions. The obtained results indicate an indirect metabolic relationship between the biosynthesis of polyene antibiotics and cytokinins in soil streptomycetes and provide a basis for the regulation of the biotechnological process for bioproduct formation with the appropriate quantitative composition of its components.

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IKEDA, YOKO, SHUICHI GOMI, KAZUTERU YOKOSE, HIROSHI NAGANAWA, TAKAKO IKEDA, MAYUMI MANABE, MASA HAMADA, SHINICHI KONDO, and HAMAO UMEZAWA. "A new streptomycin group antibiotic produced by Streptomyces sioyaensis." Journal of Antibiotics 38, no. 12 (1985): 1803–5. http://dx.doi.org/10.7164/antibiotics.38.1803.

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Tanaka, Yukinori, Mamoru Komatsu, Susumu Okamoto, Shinji Tokuyama, Akira Kaji, Haruo Ikeda, and Kozo Ochi. "Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes." Applied and Environmental Microbiology 75, no. 14 (May 15, 2009): 4919–22. http://dx.doi.org/10.1128/aem.00681-09.

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ABSTRACT Certain streptomycin resistance mutations (i.e., rpsL and rsmG) result in the overproduction of antibiotics in various actinomycetes. Moreover, rpsL rsmG double-mutant strains show a further increase in antibiotic production. rpsL but not rsmG mutations result in a marked enhancement of oligomycin production in Streptomyces avermitilis and erythromycin production in Saccharopolyspora erythraea, accompanied by increased transcription of a key developmental regulator gene, bldD, in the latter organism.

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Zhang, Zheren, Chao Du, Frédérique de Barsy, Michael Liem, Apostolos Liakopoulos, Gilles P. van Wezel, Young H. Choi, Dennis Claessen, and Daniel E. Rozen. "Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation." Science Advances 6, no. 3 (January 2020): eaay5781. http://dx.doi.org/10.1126/sciadv.aay5781.

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One of the hallmark behaviors of social groups is division of labor, where different group members become specialized to carry out complementary tasks. By dividing labor, cooperative groups increase efficiency, thereby raising group fitness even if these behaviors reduce individual fitness. We find that antibiotic production in colonies of Streptomyces coelicolor is coordinated by a division of labor. We show that S. coelicolor colonies are genetically heterogeneous because of amplifications and deletions to the chromosome. Cells with chromosomal changes produce diversified secondary metabolites and secrete more antibiotics; however, these changes reduced individual fitness, providing evidence for a trade-off between antibiotic production and fitness. Last, we show that colonies containing mixtures of mutants and their parents produce significantly more antibiotics, while colony-wide spore production remains unchanged. By generating specialized mutants that hyper-produce antibiotics, streptomycetes reduce the fitness costs of secreted secondary metabolites while maximizing the yield and diversity of these products.

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Matselyukh, B. P., S. L. Golembiovska, and O. I. Bambura. "Screening of Soil Streptomycetes – Producers of Antibiotics against Phytopathogenic Bacteria." Mikrobiolohichnyi Zhurnal 82, no. 5 (October 17, 2020): 36–40. http://dx.doi.org/10.15407/microbiolj82.05.036.

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Soil is an inexhaustible source of bacteria of the genus Streptomyces – the producers of the vast majority of known antibiotics that are successfully used in medicine, veterinary and agriculture. The emergence and spread of pathogenic bacteria resistance to antibiotics requires the search for new antibiotic compounds capable of overcoming this problem. Aim. The purpose of this work was to isolate streptomycetes from soil samples of Kyiv and the Kyiv region and study their antibiotic activity against four strains of the different species of phytopathogenic bacteria. Methods. A suspension of soil in distilled water was sown on solid Chapek or corn-soybean medium in Petri dishes, in which trimethoprim and nystatin were introduced to inhibit bacterial and fungal growth. The antibiotic activity of the streptomycetes was tested by setting their agar discs on lawns of phytopathogenic bacteria in Petri dishes. Antibiotics were extracted from the streptomycetes agar cultures with a mixture of chloroform and acetone (2:1), dried in a rotary vacuum evaporator, dissolved in ethanol, separated and purified by thin layer chromatography on aluminum plates (Silica gel 60 F254 from Merck KGaA). The UV/Vis absorption spectra of the antibiotics were measured with a Beckman DU 8 spectrophotometer. Results. 10 strains of streptomycetes were isolated from the soil samples of Kyiv and the Kyiv region, whose antibiotic activity was tested against four phytopathogenic bacteria using the agar block method. Three of the streptomycetes – B8, SK and KZ, formed growth inhibition zones of different phytopathogens on complete medium in Petri dishes, among which the strain SK was the most active. This strain showed antibiotic activity against all four phytopathogenic bacteria – P. syringae 8511, P. carotovorum 8982, C. michiganensis 10 and X. campestris 8003. Conclusions. The results obtained are of interest for the protection of sensitive plants by isolated antibiotics against phytopathogenic bacteria in hothouse conditions.

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de Lima Procópio, Rudi Emerson, Ingrid Reis da Silva, Mayra Kassawara Martins, João Lúcio de Azevedo, and Janete Magali de Araújo. "Antibiotics produced by Streptomyces." Brazilian Journal of Infectious Diseases 16, no. 5 (September 2012): 466–71. http://dx.doi.org/10.1016/j.bjid.2012.08.014.

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Dissertations / Theses on the topic "Streptomyces; Antibiotics"

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Cooper, Howard N. "Tetronasin biosynthesis in Streptomyces longisporoflavus." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240902.

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Smith, Todd M. "Genetic and biochemical studies of thiostrepton biosynthesis in Streptomyces laurentii /." Thesis, Connect to this title online; UW restricted, 1993. http://hdl.handle.net/1773/8187.

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Aubry, Céline. "Towards combinatorial biosynthesis of pyrrolamide antibiotics in Streptomyces." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS245.

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Depuis plus de 80 ans, le métabolisme spécialisé nous fournit de nombreuses molécules utilisées en médecine, en particulier comme anti-infectieux. Aujourd’hui, avec l’augmentation mondiale de la résistance aux antimicrobiens, de nouveaux antibiotiques sont indispensables. Une des réponses à cette pénurie grave pourrait provenir de la biologie synthétique. Dans le domaine du métabolisme spécialisé, la biologie synthétique est utilisée en particulier pour la biosynthèse de métabolites non naturels. Parmi les métabolites spécialisés, les peptides non ribosomiques constituent une cible attrayante, car ils nous ont déjà fourni des molécules à haute valeur clinique (ex. les antibiotiques vancomycine et daptomycine). De plus, la plupart sont synthétisés par des enzymes multimodulaires appelées synthétases de peptides non ribosomiques (NRPS), et sont diversifiés davantage par des enzymes de décoration. Ainsi, ces voies de biosynthèse se prêtent particulièrement à la biosynthèse combinatoire, consistant à combiner des gènes de biosynthèse provenant de divers groupes de gènes ou, dans le cas des NRPS, à combiner des modules ou domaines pour créer de nouvelles enzymes. Cependant, si plusieurs études ont établi la faisabilité de telles approches, de nombreux obstacles subsistent avant que les approches combinatoires de biosynthèse soient totalement efficaces pour la synthèse de nouveaux métabolites. Les travaux présentés ici s’inscrivent dans le cadre d’un projet visant à comprendre les facteurs limitant les approches de biosynthèse combinatoire basées sur les NRPS, en utilisant une approche de biologie synthétique. Nous avons choisi de travailler avec les NRPS responsables de la biosynthèse des pyrrolamides. En effet, ces NRPS sont constitués uniquement de modules et de domaines autonomes, et donc particulièrement adaptés aux manipulations génétiques et biochimiques. La caractérisation du groupe de gènes de biosynthèse du pyrrolamide anthelvencine constitue la première partie de cette thèse et nous a fourni de nouveaux gènes pour notre étude. La deuxième partie a consisté à construire de vecteurs intégratifs modulaires, outils essentiels pour la construction et l’assemblage de cassettes génétiques. La dernière partie présente la reconstruction du groupe de gènes du pyrrolamide congocidine, basée sur la construction et l’assemblage de cassettes de gènes synthétiques. Dans l’ensemble, ces travaux ouvrent la voie à de futures expériences de biosynthèse combinatoire, expériences qui devraient contribuer à une meilleure compréhension du fonctionnement précis des NRPS
For more than 80 years, specialized metabolism has provided us with many molecules used in medicine, especially as anti-infectives. Yet today, with the rise of antimicrobial resistance worldwide, new antibiotics are crucially needed. One of the answers to this serious shortage could arise from synthetic biology. In the field of specialized metabolism, synthetic biology is used in particular to biosynthesize unnatural metabolites. Among specialized metabolites, non-ribosomal peptides constitute an attractive target as they have already provided us with clinically valuable molecules (e.g. the vancomycin and daptomycin antibiotics). In addition, most are synthesized by multimodular enzymes called non-ribosomal peptide synthetases (NRPS) and further diversified by tailoring enzymes. Thus, such biosynthetic pathways are particularly amenable to combinatorial biosynthesis, which consists in combining biosynthetic genes coming from various gene clusters or, in the case of NRPSs, combining modules or domains to create a new enzyme. Yet, if several studies have established the feasibility of such approaches, many obstacles remain before combinatorial biosynthesis approaches are fully effective for the synthesis of new metabolites. The work presented here is part of a project aiming at understanding the limiting factors impeding NRPS-based combinatorial biosynthesis approaches, using a synthetic biology approach. We chose to work with the NRPSs involved in the biosynthesis of pyrrolamides. Indeed, these NRPS are solely constituted of stand-alone modules and domains, and thus, particularly amenable to genetic and biochemical manipulations. The characterization of the biosynthetic gene cluster of the pyrrolamide anthelvencin constitutes the first part of this thesis, and provided us with new genes for our study. The second part involved the construction of modular integrative vectors, essential tools for the construction and assembly of gene cassettes. The final part presents the successful refactoring of the congocidine pyrrolamide gene cluster, based on the construction and assembly of synthetic gene cassettes. Altogether, this work paves the way for future combinatorial biosynthesis experiments that should help deciphering the detailed functioning of NRPSs

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Eustáquio, Alessandra da Silva. "Biosynthesis of aminocoumarin antibiotics in streptomyces generation of structural analogues by genetic engineering and insights into the regulation of antibiotic production /." [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11514125.

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McDonald, Matthew G. "Biosynthetic studies on phenazine antibiotics /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8699.

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Dong, Haijun. "Biosynthesis of validamycin A in Streptomyces hygroscopicus var. limoneus /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/8612.

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Sparkes, Andrew Windsor. "Studies of archaemycin biosynthesis." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239645.

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Marsden, Andrew F. A. "The erthromycin-producing polyketide synthase." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243196.

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9

Williams, Richard Stephen. "The molecular physiology of antibiotic production in Streptomyces coelicolor." Thesis, University of Surrey, 2000. http://epubs.surrey.ac.uk/696/.

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Kieser, Helen M. "Analysis of the genome of Streptomyces coelicolor A3(2)." Thesis, University of East Anglia, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302209.

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Books on the topic "Streptomyces; Antibiotics"

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United States International Trade Commission. In the matter of certain salinomycin biomass and preparations containing same. Washington, DC: U.S. International Trade Commission, 1996.

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2

Sinka, Katharine Jane. ppGpp and antibiotic production in streptomyces coelicolor A3(2). Norwich: University of East Anglia, 1993.

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Ozergin, K. S. Study of antibiotic synthesis by free and immobilised streptomyces coelicolor a3(2). Manchester: UMIST, 1991.

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Saxon, Mark. [The regulation of antibiotic undecylprodigiosin (Red) production in Streptomyces coelicolor A3(2): An investigation]. [s.l.]: typescript, 2000.

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5

Podmore, S. M. Phenotypic and molecular genetic studies on the production of the calcium-dependent antibiotic of streptomyces coelicolor A3(2). Manchester: UMIST, 1995.

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Chong, P. P. Molecular genetic studies on the biosynthesis and regualtion of the calcium-dependent antibiotic (CDA) production by streptomyces coelicolor A3(2). Manchester: UMIST, 1998.

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Experiment Eleven: Dark secrets behind the discovery of a wonder drug. New York, N.Y: Walker & Co., 2012.

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Zhang, Qibo. Advanced studies of blasticidin S biosynthesis. 1998.

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Guo, Jincan. Biosyntheis of Blasticidin S: Pathway and enzymes for the nucleoside formation and blastidic acid assembly. 1992.

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Saha, Jayanta Kumar. Total synthesis of (±)-bostrycin, synthesis of a chiral catechol-based C b2 s-symmetric ligand and studies directed towards the synthesis of dienoyl tetramic acid section of tirandamycin. 1986.

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Book chapters on the topic "Streptomyces; Antibiotics"

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Plater, Richard, and William R. Strohl. "Polyketide Biosynthesis: Antibiotics in Streptomyces." In Genetic Engineering of Plant Secondary Metabolism, 61–91. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2544-8_3.

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Hunter, Iain S. "Antibiotic Biosynthesis." In Genetics and Product Formation in Streptomyces, 83–85. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_11.

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Piepersberg, Wolfgang. "Antibiotic Resistance: Present State and Prospects." In Genetics and Product Formation in Streptomyces, 153–59. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_18.

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Piepersberg, Wolfgang, Peter Heinzel, Kambiz Mansouri, Ulrike Mönnighoff, and Klaus Pissowotzki. "Evolution of Antibiotic Resistance and Production Genes in Streptomycetes." In Genetics and Product Formation in Streptomyces, 161–70. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_19.

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Wohlleben, Wolfgang, Walter Arnold, Iris Behrmann, Inge Broer, Doris Hillemann, Alfred Pühler, and Eckhard Strauch. "Genetic Analysis of Different Resistance Mechanisms Against the Herbicidal Antibiotic Phosphinothricyl-Alanyl-Alanine." In Genetics and Product Formation in Streptomyces, 171–83. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_20.

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Störl, K., J. Störl, and Ch Zimmer. "DNA Topoisomerases from Streptomyces and Their Inhibition by Some Antibiotic and Antitumoractive Agents." In Genetics and Product Formation in Streptomyces, 321–26. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_38.

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Speedie, Marilyn K., James J. Zulty, Bonnie M. Fox, and Kimberlee K. Wallace. "Methylation Pathways in Antibiotic Producing Streptomycetes." In Secondary-Metabolite Biosynthesis and Metabolism, 61–76. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3012-1_5.

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Novotná, J., J. Neužil, I. Vančurová, V. Běhal, and Z. Hošt’álek. "Enzymes and Coenzymes of the Terminal Part of the Antibiotic Biosynthetic Pathway in Streptomycetes Producing Tetracyclines." In Genetics and Product Formation in Streptomyces, 137–43. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_16.

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Miguélez, Elisa M., Carlos Hardisson, and Manuel B. Manzanal. "Peptidoglycan Synthesis During Hyphal Elongation in Streptomyces antibioticus." In Bacterial Growth and Lysis, 189–96. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-9359-8_22.

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Strauch, E., E. Takano, and M. J. Bibb. "Induction of the Stringent Response in Streptomyces Coelicolor A3(2) and Its Possible Role in Antibiotic Production." In Genetics and Product Formation in Streptomyces, 29–33. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5922-7_5.

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Conference papers on the topic "Streptomyces; Antibiotics"

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Loboda, M., and L. Biliavska. "Biosynthesis of polyene antibiotics and phytohormones under the action of exogenous β-sitosterol by soil Streptomycete Streptomyces Netropsis IMV Ac-5025." In National Scientific Symposium With International Participation: Modern Biotechnologies – Solutions to the Challenges of the Contemporary World. Institute of Microbiology and Biotechnology, Republic of Moldova, 2021. http://dx.doi.org/10.52757/imb21.085.

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Salimath, Mamatha B., Shobha K S, and Onkarappa R. "Anti-lymphocytic enzyme L-asparaginase from Streptomyces antibioticus of Western Ghat Soil." In Annual International Conference on Advances in Biotechnology (BIOTECH 2016). Global Science & Technology Forum (GSTF), 2016. http://dx.doi.org/10.5176/2251-2489_biotech16.26.

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Ugur, A., and O. Ceylan. "Isolation and screening of novel antibiotic producing Streptomyces from southwest Turkey soils." In Proceedings of the International Conference on Antimicrobial Research (ICAR2010). WORLD SCIENTIFIC, 2011. http://dx.doi.org/10.1142/9789814354868_0080.

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