Relevant bibliographies by topics / STRESS IDENTIFICATION / Dissertations / Theses
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Dissertations / Theses on the topic 'STRESS IDENTIFICATION'

Author: Grafiati
Published: 11 September 2023

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1

Dorfi, Hans Robert. "Acoustoelasticity: stress identification based on ultrasonic measurements /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487856906257899.

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2

Howell, Geoffrey Peter. "Identification of plastic strain using thermoelastic stress analysis." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/412636/.

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Identification of regions containing plastic strain arising from the welding process is performed through the application of thermoelastic stress analysis (TSA) and finite element (FE) modelling. An approach is developed that removes the requirement to have a physical reference specimen for the component studied by developing a 'synthetic reference bitmap' using finite element analysis. The regions containing plastic strain can be identified with TSA by collecting data from a 'reference' plastic strain free specimen from the TSA data and creating a resultant bitmap. Here, a synthetic bitmap is
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3

Chierichetti, Maria. "Combined analytical and experimental approaches to dynamic component stress prediction." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/44850.

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In modern times, the ability to investigate the aeroelastic behavior of dynamic components on rotorcraft has become essential for the prediction of their useful fatigue life. At the same time, the aeroelastic modeling of a rotorcraft is particularly complex and costly. Inaccuracies in numerical predictions are mostly due to imprecisions in the structural modeling, to the presence of structural degradation or to the limited information on aerodynamic loads. The integration of experimental measurements on dynamic components such as rotor blades has the potential to improve fatigue estimation, au
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4

Stålhand, Jonas. "Arterial mechanics : noninvasive identification of constitutive parameters and residual stress /." Linköping : Dept. of Mechanical Engineering, Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/tek941s.pdf.

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5

Emery, Trystan Ross. "Identification of damage in composite materials using thermoelastic stress analysis." Thesis, University of Southampton, 2007. https://eprints.soton.ac.uk/51292/.

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A quantitative damage assessment methodology for composite materials has been achieved using Thermoelastic Stress Analysis (TSA). The TSA technique provides fullfield data which is collected in a non-contacting and real time manner. The damage assessment methodology proposed requires a means of calibrating and temperature correcting the thermoelastic signal; these are developed and presented in this thesis. The thermoelastic theory for calibrating thermoelastic data from orthotropic bodies has traditionally been based on a stress formulation. There are difficulties in calibrating orthotropic m
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6

Li, Aiqing. "Identification Of Proteins Associated With Insect Diapause And Stress Tolerance." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1211487603.

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7

Nguyen, Cong Uy. "Hybrid stress visco-plasticity : formulation, discrete approximation, and stochastic identification." Thesis, Compiègne, 2022. http://www.theses.fr/2022COMP2695.

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Dans cette thèse, une nouvelle approche est développée pour les problèmes de viscoplasticité et de dynamique non linéaire. En particulier, les équations variationnelles sont élaborées selon le principe de Helligner-Reissner, de sorte que les champs de contrainte et de déplacement apparaissent comme des champs inconnus sous la forme faible. Trois nouveaux éléments finis sont développés. Le premier élément fini est formulé pour le problème axisymétrique, dans lequel le champ de contraintes est approximé par des polynômes d’ordre inférieur tels que des fonctions linéaires. Cette approche donne de
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8

Gauthier, David. "Financial stress and the business cycle." Thesis, Paris 1, 2019. http://www.theses.fr/2019PA01E057.

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Le fil directeur de cette thèse est l’étude du stress financier et en particulier de ses implications pour les fluctuations économiques. Comment expliquer l’impact des crises financières ? Quel est le rôle du système bancaire dans la propagation des chocs financiers ? Comment reconnaître et prévoir une crise financière ? Chacun des chapitres de cette thèse a pour but d’apporter des éléments de réponse nouveaux à ces grandes questions de la macroéconomie moderne. Dans le premier chapitre, réalisé en collaboration avec Yvan Bécard, nous estimons un modèle d’équilibre général dans lequel les banq
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9

Martínez, Cebrián Gerard 1992. "Identification of novel histone marks required for the transcriptional stress response." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/668153.

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Upon environmental stresses such as temperature fluctuations or increases in osmolarity, yeast Saccharomyces cerevisiae induces a transcriptional reprograming in order to survive and adapt to the stress. Histone post-translational modifications are key regulatory elements known to modulate transcription. By using a complete collection of histone mutants, we performed a high throughput transcriptional screening to assess the histone residues required for a proper induction of stressresponsive fluorescent reporters upon heat and osmotic stress. From our screening, we could extract general c
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10

Herrmann, Leonie. "Identification and characterization of novel candidate molecules for posttraumatic stress disorder." Diss., Ludwig-Maximilians-Universität München, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-157327.

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11

Tripp, Charlotte E. "The identification and characterisation of novel suppressors of DNA replication stress." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/20385/.

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Replication stress is present in cancers cells at higher than normal levels due to the increased proliferation caused by oncogene activation. This results in elevated levels of phosphorylated RPA2 (pRPA2) and DNA damage, which can ultimately result in genetic instability. By inhibiting suppressors of replication stress, it may be possible to target this cancer-specific phenotype to selectively kill tumour cells. Attempts were therefore made to develop a high throughput whole genome RNAi screen to detect increased endogenous levels of pRPA2 foci formation following gene knockdown, however, this
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12

Müller-Rudorf, Alina [Verfasser], Anna Lena [Akademischer Betreuer] Illert, and Robert [Akademischer Betreuer] Zeiser. "Crosstalk between the stress axes: Identification of the NIPA - p53 interaction." Freiburg : Universität, 2019. http://d-nb.info/1231232285/34.

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13

Adams, Leslie Allen. "Identification of early stress in a zebrafish model of familial ALS." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1375373734.

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14

Simoni, L. "Gene-trap based identification of stress-activated genes in Arabidopsis thaliana." Doctoral thesis, Università degli Studi di Milano, 2007. http://hdl.handle.net/2434/56604.

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We employed a large scale gene trap approach to identify genes involved in osmotic stress responses. This strategy allows the analysis of stress-induced Gus expression, so we realized a selective screening of the EXOTIC (EXOn Trapping Insert Consortium) collection, by using Mannitol as selective agent. Moreover this strategy allows the analysis of cell-specific Gus expression, so we searched the EXOTIC lines for guard cell-specific activation of the reporter gene. We identified 3 lines that showed GUS expression only after exposure to Mannitol. In one line we mapped the transposon insertion in
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15

Partridge, Charles Randal. "Identification and molecular characterization of novel genomic targets in oxidant-induced vascular injury." Diss., Texas A&M University, 2005. http://hdl.handle.net/1969.1/5024.

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Gene expression was examined in vascular smooth muscle cells to study the complex interaction between oxidative injury and the pathogenesis of vascular disease. Extensive vascular remodeling coupled to increased production of 8-epi-PGF2α nuclear localization of NFκB, and alterations in glutathione homeostasis were identified as major responses of the vascular wall to oxidative stress. Transcriptional profiling studies, supported by immunohistochemistry and in situ hybridization measurements, identified genes involved in adhesion and extracellular matrix deposition (α1 integrin, collag
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16

Misiewicz, Michael. "Identification of a novel endoplasmic reticulum stress response element regulated by XBP1." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116963.

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The Prion protein (PrP), which is the causative agent of scrapie diseases, has a still unclear physiological function, despite 30 years of research on its nature. However, a preponderance of evidence is beginning to support the idea that cellular prion protein (PrPC) has a pro-survival function. Here, we study the regulation of the prion protein gene (PRNP) in this context, as the regulation of the PRNP gene is not well understood. By homology, we identified in the PRNP a novel promoter element which bears similarity to the Endoplasmic Reticulum Stress Response Element (ERSE). This novel ERSE
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17

Barth, Alexander [Verfasser]. "Identification of genetic factors involved in the regulation of stress / Alexander Barth." Bonn : Universitäts- und Landesbibliothek Bonn, 2012. http://d-nb.info/1044082038/34.

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18

Edmond, Avril. "The identification, rationalization and correlation of physiological and behavioural responses to stress." Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414140.

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19

Raymondi, Luis Guillermo Antezana, Fabricio Eduardo Aguirre Guzman, Jimmy Armas-Aguirre, and Paola Agonzalez. "Technological solution for the identification and reduction of stress level using wearables." IEEE Computer Society, 2020. http://hdl.handle.net/10757/656578.

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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.<br>In this article, a technological solution is proposed to identify and reduce the level of mental stress of a person through a wearable device. The proposal identifies a physiological variable: Heart rate, through the integration between a wearable and a mobile application through text recognition using the back camera of a smartphone. As part of the process, the technological solution shows a list of guidelines depending on the level of stress
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20

Danquah, Agyemang. "Identification and validation of key factors of stress tolerance in Arabidopsis thaliana." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA112052.

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Les stress abiotiques sont la cause principale des pertes de rendement agricole dans le monde. Aujourd'hui, le développement d'espèces capables de résister à ces stress est d'une importance majeure, en particulier dans le contexte de la croissance démographique actuelle et du changement climatique mondial. La phytohormone acide abscissique (ABA) contrôle divers processus cellulaires et induit un signal de protection des plantes contre les stress abiotiques. Parmi les différents évènements moléculaires impliqués dans la voie de signalisation de l'ABA, les cascades de signalisation des mitogen a
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21

Bernardo, Letizia. "IDENTIFICATION AND CHARACTERIZATION OF PROTEINS INVOLVED IN BIOTIC STRESS RESISTANCE OF CEREALS." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3426966.

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Leaf rust is one of the most important diseases of barley (Hordeum vulgare) and is caused by the biotrophic fungal pathogen Puccinia hordei. The rust fungi penetrate barley leaves through stomata and colonize cells of the mesophyll, then growing systemically through the leaf vascular tissue. The leaf rust resistance gene Rph15 is of outstanding interest for resistance breeding because it confers resistance to over 350 Puccinia hordei isolates collected from around the world (Weerasena et al. 2004). Plant-pathogen interactions activate many cellular signalling processes and, most likely, chan
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22

El, Khatib Nour. "Identification des mécanismes moléculaires et physiopathologiques impliqués dans la dystrophie facioscapulohumérale." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT039.

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La dystrophie musculaire facioscapulohumérale (FSHD) est une maladie autosomique dominante, caractérisée par une faiblesse et une atrophie progressive de certains muscles squelettiques. La FSHD est liée à une répression inefficace de la région des macrosatellites D4Z4 sur le chromosome 4, entraînant l'expression inappropriée dans le muscle squelettique, d’un gène à double homeobox 4 (DUX4), et la dérégulation des gènes avoisinants. La surexpression de DUX4 est responsable du phénotype atrophié des myotubes FSHD et induit la dérégulation de gènes impliqués dans la réponse au stress oxydant. Mal
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23

Ugur, Zafer. "Mass Spectroscopic Identification and Quantification of Protein Carbonyls." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/386.

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It is well established that free radical mediated oxidative stress plays a critical role in aging and age-related diseases. Among the post-translational protein modifications, carbonylation has attracted a great deal of attention due to its irreversible and irreparable nature. Despite the fact that protein carbonylation is associated with a series of physiological and pathological processes, there are still issues to be clarified such as why certain proteins are more vulnerable to modification, what are the locations of the protein modifications, and how does the nature of the oxidant affect t
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24

Salvo, Eliana. "Identification and functional analysis of genes associated with oncogenesis." Doctoral thesis, Università di Catania, 2014. http://hdl.handle.net/10761/1491.

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A RMD, mapping at the 6q26-27 region, which harbored a locus of senescence SEN6 was also implicated with tumorigenesis. One cDNA clone mapped within the RMD was recovered, it was a putative novel gene that encodes a protein without any homology with known sequences, named CATP (Cytomembrane-Associated Trafficking Protein). Modifications of its sequence across evolution, especially in Great Apes, were evaluated. Mutational analysis allowed to identify different alleles of the gene. Alleles were analyzed for association with some human pathologies. Functional analysis was performed in S. cerev
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25

Brottsjö, Johan, and Marie Andersson. "Estetisk arbetskraft: negativ stress eller ökat välmående genom rollidentifikation." Thesis, Karlstads universitet, Avdelningen för företagsekonomi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-45405.

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Aesthetic labour means that a person with a certain physical aptitude is required. Previous researcher in this field has essentially been focusing on the business benefits from front-line employees as reinforcement to their image. Furthermore, researches have discussed how the employees experience the aesthetic requirements and have found negative effects. Motivation research have, on the other hand, shown that if a person can identify with the requirements it can create wellbeing, through the creation of role identification. Consequently, the research shows different effects of aesthetic requ
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26

Akter, Shamima. "Identification of common and unique stress responsive genes of Arabidopsis thaliana under different abiotic stress through RNA-Seq meta-analysis." Thesis, Virginia Tech, 2018. http://hdl.handle.net/10919/82036.

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Abiotic stress is a major constraint for crop productivity worldwide. To better understand the common biological mechanisms of abiotic stress responses in plants, we performed meta-analysis of 652 samples of RNA sequencing (RNA-Seq) data from 43 published abiotic stress experiments in Arabidopsis thaliana. These samples were categorized into eight different abiotic stresses including drought, heat, cold, salt, light and wounding. We developed a multi-step computational pipeline, which performs data downloading, preprocessing, read mapping, read counting and differential expression analyses for
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27

Schilirò, Elisabetta. "Stress proteins and identification of interacting partners in the resurrection plant Craterostigma plantagineum." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=962336459.

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28

McLaughlin, Catherine A. "The role of identification in stress and well-being in burn care professionals." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ61468.pdf.

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29

Polato, Frederica. "Identification and characterisation of new genes important for p53- dependent, stress-induced apoptosis." Thesis, Open University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424595.

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30

Vieira, Natacha Cristiana dos Santos. "Identification of transcription factors regulating cork oak UNK1 gene during abiotic stress response." Master's thesis, ISA/UL, 2017. http://hdl.handle.net/10400.5/13961.

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Mestrado em Engenharia Agronómica - Protecção das Plantas - Instituto Superior de Agronomia - UL<br>O sobreiro (Quercus suber L.) é uma árvore autóctone do Mediterrâneo que desempenha um papel-chave no seu ecossistema. A relevância económica da espécie, aliada ao seu declínio populacional, tanto devido a ameaças biológicas (ex.: P. cinnamomi), como abióticas (ex.: calor e secura), levaram a um acrescido interesse nesta árvore. Num projecto anterior (SuberStress) do laboratório de acolhimento foram selecionados 10 genes diferencialmente expressos em diferentes stresses aplicados separadamente,
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31

Bickel, Cory Lyn. "Identification of Genomic Regions Involved in Stress Responsiveness in Flax by Genetic Mapping." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301676557.

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32

Martini, Cecilia. "Identification and characterization of new virulence factors in Enterococcus faecalis." Caen, 2014. http://www.theses.fr/2014CAEN2064.

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Dans cette étude, nous nous sommes focalisés sur l'identification et la caractérisation de nouveaux facteurs de virulence chez Enterococcus faecalis. SlyA est un régulateur transcriptionnel impliqué dans la virulence, la persistance dans les reins et le foie, ainsi que dans la survie à l'intérieur des macrophages. Nous avons recherché les conditions de stress susceptibles d’affecter la transcription du gène slyA. Parmi plusieurs contraintes testées, nous avons montré que les sels biliaires induisaient l'expression de slyA. Des études transcriptomiques avaient suggéré que SlyA pouvait être un r
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33

Jonavičienė, Kristina. "Genetic diversity of Phleum spp. and identification of genes involved in water stress response." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20120508_105857-18465.

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Genetic material of Lithuanian origin varieties, breeding lines and wild ecotypes representing P. pratense, P. bertolonii and P. phleoides species were studied for the most important agro-morphological and feeding value indicators as well as at the genetic level employing different biochemical–molecular markers. The water stress experiment clearly demonstrated the existence of different levels of water stress response in Phleum species, suggesting that P. phleoides might have evolved under conditions of limited water availability. “Blind” mapping by HRM was used successfully to map water stres
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34

He, Jia. "Identification and Characterization of Metal Uptake Loci in Porphyromonas gingivalis." Available to VCU users at :, 2007. http://hdl.handle.net/10156/1263.

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35

Pope, Simon Alexander Samuel. "The analysis and identification of urinary metabolites of vitamin E in man using mass spectrometry and chemical synthesis." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247078.

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Vitamin E (a-tocopherol) is the major lipid soluble antioxidant in vivo and is important for maintaining the integrity of cell membranes. Oxidative stress, defined as an imbalance between oxidants and antioxidants, has been implicated in the aetiology of numerous diseases. There is, therefore, interest in establishing methods to measure oxidative stress. It has been suggested that metabolites of vitamin E such as atocopheronolactone (a-TL), with an oxidised chroman ring, may be an indicator of in vivo oxidative stress and that the carboxyethyl-hydroxychromans (CEHCs), with a shortened phytyl s
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36

Boudsocq, Marie. "Identification de protéines kinases activées par des contraintes osmotiques chez Arabidopsis thaliana : étude des familles AtSK et SnRK2." Paris 11, 2005. http://www.theses.fr/2005PA112008.

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Dans des cultures cellulaires et des plantules d'Arabidopsis thaliana, l'hyperosmoiarité active 4 protéines kinases calcium-indépendantes n'appartenant pas à la famille MAPK. L'identification des familles de kinases impliquées a été entreprise en utilisant 2 anticorps famille-spécifiques dirigés chacun contre l'une des 2 familles candidates : les AtSK (Arabidopsis thaliana Shaggy-like kinase) et les SnRK2 (sucrose non-fermenting 1-related protein kinase 2). Des analyses de western-blot ont montré que les 2 anticorps reconnaissaient spécifiquement les 10 protéines de la famille contre laquelle
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37

Turki, Ahmed. "Identification des mécanismes physiopathologiques de la dystrophie facioscapulohumérale : rôle de la mitochondrie et du stress oxydant." Thesis, Montpellier 1, 2012. http://www.theses.fr/2012MON1T024.

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La dystrophie facioscapulohumérale (FSHD) est une dystrophie musculaire autosomique dominante, dégénérative et progressive. Les traitements élaborés jusqu'à présent n'ont pas réussi à améliorer le quotidien des patients FSHD. Plusieurs études se sont focalisées sur les mécanismes moléculaires de cette pathologie, néanmoins plusieurs d'entre elles sont contradictoires. La vision actuelle de la FSHD est celle d'une pathologie due à un mécanisme épigénétique complexe et les mécanismes moléculaires responsables de cette pathologie sont encore mal connus. Plusieurs analyses comparatives des profils
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38

Tarek, El-bashiti. "Trehalose Metabolism In Wheat And Identification Of Trehalose Metabolizing Enzymes Under Abiotic Stress Conditions." Phd thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/3/1102482/index.pdf.

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Trehalose (&amp<br>#945<br>-D-glucopyranosyl-1,1-&amp<br>#945<br>-D-glucopyranoside) is a non reducing disaccharide of glucose that occurs in a large variety of organisms, ranging from bacteria to invertebrate animals, where it serves as an energy source or stress protectant. Until recently, only few plant species, mainly desiccation tolerant &amp<br>#8216<br>resurrection&amp<br>#8217<br>plants, were considered to synthesize trehalose. Although most plant species do not appear to accumulate easily detectable amounts of trehalose, the discovery of genes for trehalose biosynthesis in Arabidopsis
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Pirot, Pierre. "Identification and characterization of the endoplasmic reticulum (ER)-stress pathways in pancreatic beta-cells." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210623.

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The endoplasmic reticulum (ER) is the organelle responsible for synthesis and folding of secreted and membranous protein and lipid biosynthesis. It also functions as one of the main cellular calcium stores. Pancreatic beta-cells evolved to produce and secrete insulin upon demand in order to regulate blood glucose homeostasis. In response to increases in serum glucose, insulin synthesis represents nearly 50% of the total protein biosynthesis by beta-cells. This poses an enormous burden on the ER, rendering beta-cells vulnerable to agents that perturb ER function. Alterations of ER homeostasis l
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40

Meves, Alexander [Verfasser]. "Identification and Characterization of Stress-Activated Signaling Networks in Human Primary Keratinocytes / Alexander Meves." Aachen : Shaker, 2004. http://d-nb.info/1181603315/34.

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41

Gonzalez, Marquez Humberto. "Réponse au stress acide chez Streptococcus thermophilus : purification, identification et caractérisation d'une protéine surexprimée." Nancy 1, 1997. http://docnum.univ-lorraine.fr/public/SCD_T_1997_0018_GONZALEZ_MARQUEZ.pdf.

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Streptococcus thermophilus a suivi différentes pressions de sélection (stress) lors des protocoles de fabrication ; par exemple, les montées et descentes de la température et l'acidification du milieu. Dans ce travail, nous mettons en évidence, dans un premier temps, que Streptococcus thermophilus PB18 surexprime une protéine de masse moléculaire apparente de 16 kDa quand elle arrive en phase stationnaire de croissance en milieu M17 (lactose 20g/l, pH≤5). Nous avons également observé que cette protéine est surexprimée quand la croissance est arrêtée brusquement par addition d'acide lactique ex
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42

Rezaïki, Lahcen. "Métabolisme respiratoire chez Lactococcus lactis dans un environnement oxydant et identification de composants de la chaîne respiratoire." Paris 11, 2004. http://www.theses.fr/2004PA112133.

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Lactococcus lactis est tres utilisee dans l'industrie agroalimentaire. A cette fin elle a ete principalement etudiee pour ses capacites fermentaire. Le dogme des bacteries lactiques exclusivement fermentaire est caduque depuis qu'il a ete montre que l. Lactis est capable d'adopter un metabolisme respiratoire en presence d'heme exogene et d'oxygene. Dans ces conditions un doublement de la biomasse, une augmentation du ph et la survie largement augmentee, sont observees par rapport a un metabolisme fermentaire. Mon projet de these s'est focalise sur le metabolisme respiratoire de l. Lactis et s'
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43

Thornton, Elizabeth Claire. "Identification and characterisation of a novel β subunit of AMP-activated protein kinase." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312986.

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44

Holbrook, Eric. "Identification and Characterization of Histoplasma capsulatum extracellular proteins and their roles in virulence." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1353964000.

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45

TUVERI, ROSSANA. "Identification & characterization of natural and synthetic compounds as new anticancer agents." Doctoral thesis, Università degli Studi di Cagliari, 2016. http://hdl.handle.net/11584/266770.

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This thesis collects the work I have done during the three-year PhD Course. During my first year I have started a path that has allowed me to acquire different techniques devoted to set up and maintain primary cell cultures and cancer derived cell lines as well as to evaluate the cytotoxicity of potential novel synthetic inhibitors of human cancer cells. Part of the second and all the third year was spent at the University of Cape Town, South Africa, in the laboratory of prof. Ariel Katz under the supervision of proff. Roger Hunter and Catherine H. Kaschula investigating the anticancer a
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Azizi, Samir Lalla Amina. "Identification et caractérisation de nouveaux gènes de réponse au stress induit par la pancréatite aiguë." Université Joseph Fourier (Grenoble), 2003. http://www.theses.fr/2003GRE18002.

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L'approche systématique et la technique des micropuces à ADN, nous a permis de montrer que parmi 8000 gènes analysés, 239 présentent une expression différente entre le pancréas sain et le pancréas au cours de la pancréatite : 107 gènes étaient sur-exprimés et 132 gènes étaient sous-exprimés. Parmi ces gènes, 96 correspondaient à des gènes non répertoriés auparavant. Dans le but d'identifier de nouveaux mécanismes de défense cellulaire, nous avons caractérisé deux nouveaux gènes. Le premier gène code une protéine de 49 kDa, appelé PIP 49 (Pancreatitis Induced Protein). Il s'agit d'une protéine
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47

BALDI, GIORGIO. "IDENTIFICATION AND CHARACTERIZATION OF STRESSED REPLICATION FORK INTERMEDIATES." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/609359.

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The DNA replication machinery encounters a number of obstacles while duplicating the genome, which put the replicative apparatus under stress. Cells have developed a number of mechanisms to overcome replication stress sources. However, in the presence of chronic stress, or after loss of key factors that help to deal with this stress, a range of deleterious events can occur. One of the main pathways implicated in DNA damage sensing and response is DNA damage checkpoint. When DNA replication fork progression is blocked, checkpoint activation ensures structural stability of the replisome componen
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48

Alino-Wilcockson, David Paul. "A study of underachievement in a middle school : identification, measurement, perspectives and change." Thesis, De Montfort University, 1999. http://hdl.handle.net/2086/7984.

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Mukhopadhyay, Suman. "Identification and characterization of genes that protect Escherichia coli from hydrogen peroxide mediated oxidative stress." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ30161.pdf.

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50

Scharf, Sebastian [Verfasser], and Mathias [Akademischer Betreuer] Schmidt. "Identification of novel molecular factors involved in individual stress vulnerability / Sebastian Scharf. Betreuer: Mathias Schmidt." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1029040397/34.

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