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1

Huo, Yunlong, Yana Cheng, Xuefeng Zhao, Xiao Lu, and Ghassan S. Kassab. "Biaxial vasoactivity of porcine coronary artery." American Journal of Physiology-Heart and Circulatory Physiology 302, no. 10 (2012): H2058—H2063. http://dx.doi.org/10.1152/ajpheart.00758.2011.

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The passive mechanical properties of blood vessel mainly stem from the interaction of collagen and elastin fibers, but vessel constriction is attributed to smooth muscle cell (SMC) contraction. Although the passive properties of coronary arteries have been well characterized, the active biaxial stress-strain relationship is not known. Here, we carry out biaxial (inflation and axial extension) mechanical tests in right coronary arteries that provide the active coronary stress-strain relationship in circumferential and axial directions. Based on the measurements, a biaxial active strain energy f
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2

SHAHIDIAN, AZADEH, and ARASH GHORBANNIA HASSANKIADEH. "STRESS ANALYSIS OF INTERNAL CAROTID ARTERY WITH LOW STENOSIS LEVEL: THE EFFECT OF MATERIAL MODEL AND PLAQUE GEOMETRY." Journal of Mechanics in Medicine and Biology 17, no. 06 (2017): 1750098. http://dx.doi.org/10.1142/s0219519417500981.

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Stress concentration in carotid stenosis has been proven to assist plaque morphology in disease diagnosis and vulnerability. This work focuses on numerical analysis of stress and strain distribution in the cross-section of internal carotid artery using a 2D structure-only method. The influence of four different idealized plaque geometries (circle, ellipse, oval and wedge) is investigated. Numerical simulations are implemented utilizing linear elastic model along with four hyperelastic constitutive laws named neo-Hookean, Ogden, Yeoh and Mooney–Rivlin. Each case is compared to the real geometry
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3

YAMADA, Hiroshi, and Noriyuki SAKATA. "905 Stress/strain analyses of common carotid artery using various hyperelastic material models." Proceedings of Conference of Kyushu Branch 2010.63 (2010): 327–28. http://dx.doi.org/10.1299/jsmekyushu.2010.63.327.

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4

VALENCIA, ALVARO, MAXIMILIANO ROJO, RODRIGO RIVERA, and EDUARDO BRAVO. "SENSITIVITY ANALYSIS OF COMPUTATIONAL STRUCTURAL DYNAMICS IN A CEREBRAL ANEURYSM MODEL TO WALL THICKNESS AND MODEL." Journal of Mechanics in Medicine and Biology 12, no. 03 (2012): 1250054. http://dx.doi.org/10.1142/s0219519411004630.

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Intracranial saccular aneurysms tend to be thin walled and stiffer compared with a normal artery. The current work describes computational structural dynamics (CSD) in an anatomically realistic model of a cerebral aneurysm located in the ophthalmic region, using different wall thickness, model data for the artery and aneurysm, and geometry size. The model was obtained from three-dimensional rotational angiography image data. The wall was assumed three-dimensional hyperelastic solid with different thickness in the artery and in the aneurysm regions. The effects of carotid siphon length are repo
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5

XU, CHUANGYE, XIUJIAN LIU, LIANQIANG PAN, et al. "NUMERICAL ANALYSIS OF BALLOON EXPANDABLE STENT DEPLOYMENT INSIDE A PATIENT-SPECIFIC STENOTIC CORONARY ARTERY TO INVESTIGATE THE INSTANT MECHANICAL BEHAVIORS." Journal of Mechanics in Medicine and Biology 17, no. 07 (2017): 1740037. http://dx.doi.org/10.1142/s0219519417400371.

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The instant mechanical behaviors of stenotic coronary artery and deployed stents have significant impacts on percutaneous coronary intervention prognosis. However, they could not be obtained directly from the current examination techniques, which are commonly used in clinical practice. Thus, we intend to investigate the instantaneous mechanical behaviors of deployed stent and artery through virtually stenting technology based on a real clinical case in assessment of geometric and biomechanical characteristics. Method: Finite element analysis models, including rigid guide catheter, six-folded b
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6

Tsai, Ming Chang, and Shyh Chour Huang. "The Analysis of Pulse Pressure by Vascular Strain." Applied Mechanics and Materials 256-259 (December 2012): 2383–86. http://dx.doi.org/10.4028/www.scientific.net/amm.256-259.2383.

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The objective of this paper is to use the Noninvasive Strain Measurement System to monitor the pulse pressure of the blood’s undulation in the artery as an index for the clinical diagnosis of arteriosclerosis. In the study, a strain-measuring device (350Ω) is affixed to the left side of the radial styloid process, on the surface of the skin, and is connected to the Strain FleXense. An artery-pressuring tape is set on the left humerus, and the measurement of the wavelength and frequency of the heartbeat is taken to compare with the clinical artery wave. The results show that when the subject is
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7

Tsai, Ming Chang, and Shyh Chour Huang. "The Analysis of Pulse Pressure by Vascular Strain." Applied Mechanics and Materials 268-270 (December 2012): 1194–97. http://dx.doi.org/10.4028/www.scientific.net/amm.268-270.1194.

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The objective of this paper is to use the Noninvasive Strain Measurement System to monitor the pulse pressure of the blood’s undulation in the artery as an index for the clinical diagnosis of arteriosclerosis. In the study, a strain-measuring device (350Ω) is affixed to the left side of the radial styloid process, on the surface of the skin, and is connected to the Strain FleXense. An artery-pressuring tape is set on the left humerus, and the measurement of the wavelength and frequency of the heartbeat is taken to compare with the clinical artery wave. The results show that when the subject is
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8

Zhang, Wei, Carly Herrera, Satya N. Atluri, and Ghassan S. Kassab. "Effect of Surrounding Tissue on Vessel Fluid and Solid Mechanics." Journal of Biomechanical Engineering 126, no. 6 (2004): 760–69. http://dx.doi.org/10.1115/1.1824128.

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There is no doubt that atherosclerosis is one of the most important health problems in the Western Societies. It is well accepted that atherosclerosis is associated with abnormal stress and strain conditions. A compelling observation is that the epicardial arteries develop atherosclerosis while the intramural arteries do not. Atherosclerotic changes involving the epicardial portion of the coronary artery stop where the artery penetrates the myocardium. The objective of the present study is to understand the fluid and solid mechanical differences between the two types of vessels. A finite eleme
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9

Ryo, Keiko, Hiroya Kawai, Kouhei Yamawaki, et al. "The Usefulness of Handgrip Stress Echocardiography With Segmental Stsystolic Strain Analysis in Patients With Coronary Artery Disease." Journal of Cardiac Failure 15, no. 7 (2009): S160. http://dx.doi.org/10.1016/j.cardfail.2009.07.041.

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10

Bathe, M., and R. D. Kamm. "A Fluid-Structure Interaction Finite Element Analysis of Pulsatile Blood Flow Through a Compliant Stenotic Artery." Journal of Biomechanical Engineering 121, no. 4 (1999): 361–69. http://dx.doi.org/10.1115/1.2798332.

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A new model is used to analyze the fully coupled problem of pulsatile blood flow through a compliant, axisymmetric stenotic artery using the finite element method. The model uses large displacement and large strain theory for the solid, and the full Navier-Stokes equations for the fluid. The effect of increasing area reduction on fluid dynamic and structural stresses is presented. Results show that pressure drop, peak wall shear stress, and maximum principal stress in the lesion all increase dramatically as the area reduction in the stenosis is increased from 51 to 89 percent. Further reductio
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11

Teng, Zhongzhao, Aart J. Nederveen, Aad Van der Lugt, Jonathan H. Gillard, and Lambert Speelman. "MRI-based biomechanical parameters for carotid artery plaque vulnerability assessment." Thrombosis and Haemostasis 115, no. 03 (2016): 493–500. http://dx.doi.org/10.1160/th15-09-0712.

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SummaryCarotid atherosclerotic plaques are a major cause of ischaemic stroke. The biomechanical environment to which the arterial wall and plaque is subjected to plays an important role in the initiation, progression and rupture of carotid plaques. MRI is frequently used to characterize the morphology of a carotid plaque, but new developments in MRI enable more functional assessment of carotid plaques. In this review, MRI based biomechanical parameters are evaluated on their current status, clinical applicability, and future developments. Blood flow related biomechanical parameters, including
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12

Ilardi, Federica, Ciro Santoro, Patrick Maréchal, et al. "Accuracy of global and regional longitudinal strain at peak of dobutamine stress echocardiography to detect significant coronary artery disease." International Journal of Cardiovascular Imaging 37, no. 4 (2021): 1321–31. http://dx.doi.org/10.1007/s10554-020-02121-y.

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AbstractDobutamine stress echocardiography (DSE) is sensitive but subjective diagnostic tool to detect inducible ischemia. Nowadays, speckle tracking allows an objective quantification of regional wall function. We aimed to investigate the feasibility and accuracy of global (GLS) and regional longitudinal strain (RLS) during DSE to detect significant coronary stenosis (SCS). We conducted a prospective observational multicenter study including patients undergoing DSE for suspected SCS. 50 patients with positive DSE underwent coronary angiography. Besides visual regional wall motion score index
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13

Lucitti, Jennifer L., Richard Visconti, Jacqueline Novak, and Bradley B. Keller. "Increased arterial load alters aortic structural and functional properties during embryogenesis." American Journal of Physiology-Heart and Circulatory Physiology 291, no. 4 (2006): H1919—H1926. http://dx.doi.org/10.1152/ajpheart.01061.2005.

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As in the adult dorsal aorta, the embryonic dorsal aorta is an important determinant of cardiovascular function, and increased stiffness may have secondary effects on cardiac and microcirculatory development. We previously showed that acutely and chronically increased arterial load via vitelline artery ligation (VAL) increases systemic arterial stiffness. To test the hypothesis that local dorsal aortic stiffness also increases, we measured aortic pulse-wave velocity (PWV) and assessed the active and passive properties (stress and strain) of isolated aortic segments. PWV along the dorsal aorta
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14

MATSUMOTO, Takeo, and Masaaki SATO. "Analysis of Stress and Strain Distribution in the Artery Wall Consisted of Layers with Different Elastic Modulus and Opening Angle." JSME International Journal Series C 45, no. 4 (2002): 906–12. http://dx.doi.org/10.1299/jsmec.45.906.

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15

Huo, Yunlong, Xuefeng Zhao, Yana Cheng, Xiao Lu, and Ghassan S. Kassab. "Two-layer model of coronary artery vasoactivity." Journal of Applied Physiology 114, no. 10 (2013): 1451–59. http://dx.doi.org/10.1152/japplphysiol.01237.2012.

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Since vascular tone is regulated by smooth muscle cells in the media layer, a multilayer mechanical model is required for blood vessels. Here, we performed biaxial mechanical tests in the intima-media layer of right coronary artery to determine the passive and active properties in conjunction with the passive properties of adventitia for a full vessel wall model. A two-layer (intima-media and adventitia) model was developed to determine the transmural stress and stretch across the vessel wall. The mean ± SE values of the outer diameters of intima-media layers at transmural pressure of 60 mmHg
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16

Shahed, Syeda Reham, Mohammad Ali, and Md Quamrul Islam. "NUMERICAL ANALYSIS OF HEMODYNAMIC FORCES THROUGH STENOTIC ARTERY." Journal of Mechanical Engineering 43, no. 1 (2013): 41–47. http://dx.doi.org/10.3329/jme.v43i1.15780.

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A numerical analysis is carried out to demonstrate the variation of two hemodynamic forces: wallshear stress and pressure in the flow field of stenotic artery. The artery has 75% stenosis severity withaxisymmetric cosine shaped stenosis. The wall of the vessel is considered to be rigid. A sinusoidal pulsatile flowis assumed as inlet boundary condition. During the simulation both standard k-? model of low Reynoldscorrection and standard k-? model are used. Some analysis with standard k-? model with low Reynoldscorrection show better agreement with previous experimental results. The peak wall sh
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17

YAMADA, Hiroshi, and Noriyuki SAKATA. "8G-17 Finite element stress and strain analysis for a common carotid artery with a plaque modeled by hydrostatic fluid elements." Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2010.23 (2011): 269–70. http://dx.doi.org/10.1299/jsmebio.2010.23.269.

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18

Cui, Fangsen, Asawinee Danpinid, Foad Kabinejadian, et al. "STRESS ANALYSIS OF CAROTID ARTERY STENT UNDER BENDING AND TORSION." Journal of Biomechanics 45 (July 2012): S637. http://dx.doi.org/10.1016/s0021-9290(12)70638-3.

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19

Mattiuz, A., Q. Long, C. S. König, M. W. Collins, and M. Pinelli. "Stress analysis in multicomponent plaque of human carotid artery models." Journal of Biomechanics 39 (January 2006): S400—S401. http://dx.doi.org/10.1016/s0021-9290(06)84623-3.

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20

Fung, Y. C., and S. Q. Liu. "Strain distribution in small blood vessels with zero-stress state taken into consideration." American Journal of Physiology-Heart and Circulatory Physiology 262, no. 2 (1992): H544—H552. http://dx.doi.org/10.1152/ajpheart.1992.262.2.h544.

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The active and passive deformation of a blood vessel is related to the stress in it. Any analysis of stress and strain must begin with the zero-stress state. Recent reports on large blood vessels such as the aorta, pulmonary arteries, and vena cava have shown that, at zero-stress state, blood vessels are not tubes, but opens sectors. This report presents data on the zero-stress state of small blood vessels with lumen diameters down to approximately 50 microns. Zero-stress state of a vessel was obtained by cutting the vessel into rings and then the rings into sectors; each sector is characteriz
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21

Pandit, Aditya, Xiao Lu, Chong Wang, and Ghassan S. Kassab. "Biaxial elastic material properties of porcine coronary media and adventitia." American Journal of Physiology-Heart and Circulatory Physiology 288, no. 6 (2005): H2581—H2587. http://dx.doi.org/10.1152/ajpheart.00648.2004.

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The importance of mechanical stresses and strains has become well recognized in vascular physiology and pathology. To compute the stress and strain on the various components of the vessel wall, we must know the constitutive equations for the different layers of the vessel wall. The objective of the present study is to determine the constitutive equation of the coronary artery treated as a two-layer composite: intima-media and adventitial layers. Twelve hearts were obtained from a local slaughterhouse, and the right coronary artery and left anterior descending artery were dissected free from th
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22

Jiang, Xu Dong, Xiao Yan Teng, and Dong Yan Shi. "Analysis of the Expansion Behavior and In-Stent Restenosis of Coronary by Finite Element Method." Applied Mechanics and Materials 668-669 (October 2014): 1561–64. http://dx.doi.org/10.4028/www.scientific.net/amm.668-669.1561.

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Restenosis is a re-narrowing or blockage of an artery at the same site where treatment like stent procedure has already taken place. The aim of this study is to more conclusively identify the mechanical stimulus for in-stent restenosis by means of numerical model based on the finite element method. The finite element model simulating the stent, balloon, crimping tool and artery interaction in the coronary artery is developed. The present model is used to determine the stress distribution in the artery wall followed by stent implantation. It is indicated that the compliance mismatch of stent wi
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23

TEETER, M. G., L. G. ARROYO, J. D. BAKKER, M. A. HAYES, L. VIEL, and R. J. RUNCIMAN. "Finite element analysis of wall stress in the equine pulmonary artery." Equine Veterinary Journal 42, no. 1 (2009): 68–72. http://dx.doi.org/10.2746/042516409x464131.

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24

Akbar, Noreen Sher, and S. Nadeem. "Blood flow analysis in tapered stenosed arteries with pseudoplastic characteristics." International Journal of Biomathematics 07, no. 06 (2014): 1450065. http://dx.doi.org/10.1142/s179352451450065x.

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In this paper, the blood flow through a tapered artery with a stenosis by considering axially non-symmetric but radially symmetric mild stenosis on blood flow characteristics is analyzed, assuming the flow is steady and blood is treated as Williamson fluid. Perturbation solutions have been evaluated for velocity, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different type of tapered arteries (i.e. converging tapering, diverging tapering, non-tapered artery) have been examined for different parameters of interest.
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25

Wang, Chong, Wei Zhang, and Ghassan S. Kassab. "The validation of a generalized Hooke's law for coronary arteries." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 1 (2008): H66—H73. http://dx.doi.org/10.1152/ajpheart.00703.2007.

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The exponential form of constitutive model is widely used in biomechanical studies of blood vessels. There are two main issues, however, with this model: 1) the curve fits of experimental data are not always satisfactory, and 2) the material parameters may be oversensitive. A new type of strain measure in a generalized Hooke's law for blood vessels was recently proposed by our group to address these issues. The new model has one nonlinear parameter and six linear parameters. In this study, the stress-strain equation is validated by fitting the model to experimental data of porcine coronary art
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26

Gaibazzi, Nicola, Filippo Pigazzani, Claudio Reverberi, and Thomas R. Porter. "Rest global longitudinal 2D strain to detect coronary artery disease in patients undergoing stress echocardiography: a comparison with wall-motion and coronary flow reserve responses." Echo Research and Practice 1, no. 2 (2014): 61–70. http://dx.doi.org/10.1530/erp-14-0020.

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Myocardium subtended by obstructive coronary artery disease (CAD) may show reduced left ventricle (LV) global longitudinal strain (GLS), as well as early systolic lengthening (ESL) before shortening; these can be measured at rest and may predict obstructive CAD. This study investigated whether baseline resting LV longitudinal strain measurements may be able to detect significant CAD in patients undergoing stress echocardiography (SE) and coronary angiography, who have normal resting wall motion. We selected patients with a clinical indication of coronary angiography who were previously referre
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27

Dutta, A., D. M. Wang, and J. M. Tarbell. "Numerical Analysis of Flow in an Elastic Artery Model." Journal of Biomechanical Engineering 114, no. 1 (1992): 26–33. http://dx.doi.org/10.1115/1.2895444.

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Oscillatory and pulsatile flows of Newtonian fluids in straight elastic tubes are simulated numerically with the aid of Ling and Atabek’s “local flow” assumption for the nonlinear convective acceleration terms. For the first time, a theoretical assessment of the local flow assumption is presented, and the range of validity of the assumption is estimated by comparison with perturbation solutions of the complete flow problem. Subsequent simulations with the local flow model indicate that the flow field and associated wall shear stress are extremely sensitive to the phase angle between oscillator
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28

Nazemi, M., and C. Kleinstreuer. "Analysis of Particle Trajectories in Aortic Artery Bifurcations With Stenosis." Journal of Biomechanical Engineering 111, no. 4 (1989): 311–15. http://dx.doi.org/10.1115/1.3168384.

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The fluid-particle dynamics in a two-dimensonal symmetric branching channel with local occlusions representing a diseased segment of an aortic artery bifurcation has been analyzed. The validated finite element model simulates the trajectories and landing or impact sites of spherical particles for laminar flow in bifurcation channels with generalized wall conditions. Two hypotheses relating critical wall shear stress levels and plaque formation, previously postulated by Kleinstreuer et al. (1988) and Nazemi et al. (1989), have been confirmed. Low shear stress may contribute to the onset of athe
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29

Oates, Gabriela R., Lucia D. Juarez, Barbara Hansen, Catarina I. Kiefe, and James M. Shikany. "Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study." American Journal of Health Behavior 44, no. 2 (2020): 232–43. http://dx.doi.org/10.5993/ajhb.44.2.10.

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Objectives: Nonadherence to medications has been documented, but the combined effect of social risk factors on medication nonadherence has not been investigated. Methods: We conducted a cross-sectional analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective cohort. The sample (N = 1506) included subjects who at Year 20 (2005-06) were taking prescription medications and completed a 4-item Medication Adherence Scale. Social risk factors were education of high school or less, annual household income <$25,000, high financial stra
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30

Kaewbumrung, Mongkol, Somsak Orankitjaroen, Pichit Boonkrong, Buraskorn Nuntadilok, and Benchawan Wiwatanapataphee. "Numerical Simulation of Dispersed Particle-Blood Flow in the Stenosed Coronary Arteries." International Journal of Differential Equations 2018 (August 1, 2018): 1–16. http://dx.doi.org/10.1155/2018/2593425.

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A mathematical model of dispersed bioparticle-blood flow through the stenosed coronary artery under the pulsatile boundary conditions is proposed. Blood is assumed to be an incompressible non-Newtonian fluid and its flow is considered as turbulence described by the Reynolds-averaged Navier-Stokes equations. Bioparticles are assumed to be spherical shape with the same density as blood, and their translation and rotational motions are governed by Newtonian equations. Impact of particle movement on the blood velocity, the pressure distribution, and the wall shear stress distribution in three diff
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31

Venkatesan, J., D. S. Sankar, K. Hemalatha, and Yazariah Yatim. "Mathematical Analysis of Casson Fluid Model for Blood Rheology in Stenosed Narrow Arteries." Journal of Applied Mathematics 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/583809.

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The flow of blood through a narrow artery with bell-shaped stenosis is investigated, treating blood as Casson fluid. Present results are compared with the results of the Herschel-Bulkley fluid model obtained by Misra and Shit (2006) for the same geometry. Resistance to flow and skin friction are normalized in two different ways such as (i) with respect to the same non-Newtonian fluid in a normal artery which gives the effect of a stenosis and (ii) with respect to the Newtonian fluid in the stenosed artery which spells out the non-Newtonian effects of the fluid. It is found that the resistance
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Sriyab, Somchai. "Mathematical Analysis of Non-Newtonian Blood Flow in Stenosis Narrow Arteries." Computational and Mathematical Methods in Medicine 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/479152.

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The flow of blood in narrow arteries with bell-shaped mild stenosis is investigated that treats blood as non-Newtonian fluid by using the K-L model. When skin friction and resistance of blood flow are normalized with respect to non-Newtonian blood in normal artery, the results present the effect of stenosis length. When skin friction and resistance of blood flow are normalized with respect to Newtonian blood in stenosis artery, the results present the effect of non-Newtonian blood. The effect of stenosis length and effect of non-Newtonian fluid on skin friction are consistent with the Casson m
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33

Sankar, D. S. "Perturbation analysis for pulsatile flow of Carreau fluid through tapered stenotic arteries." International Journal of Biomathematics 09, no. 04 (2016): 1650063. http://dx.doi.org/10.1142/s1793524516500637.

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The pulsatile flow of blood in a tapered narrow artery with overlapping time-dependent stenosis is mathematically analyzed, modeling blood as Carreau fluid. Perturbation method is employed for solving the resulting nonlinear system of equations along with the appropriate boundary conditions. The analytic solutions to the pressure gradient, velocity distribution, flow rate, wall shear stress and longitudinal impedance to flow are obtained in the asymptotic form. The variation of the aforesaid flow quantities with respect to various physical parameters such as maximum depth of the stenosis, angl
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34

Akbar, Noreen Sher, and S. Nadeem. "Mathematical analysis of Phan-Thien–Tanner fluid model for blood in arteries." International Journal of Biomathematics 08, no. 05 (2015): 1550064. http://dx.doi.org/10.1142/s1793524515500643.

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In the present paper, we have studied the blood flow through tapered artery with a stenosis. The non-Newtonian nature of blood in small arteries is analyzed mathematically by considering the blood as Phan-Thien–Tanner fluid. The representation for the blood flow is through an axially non-symmetrical but radially symmetric stenosis. Symmetry of the distribution of the wall shearing stress and resistive impedance and their growth with the developing stenosis is another important feature of our analysis. Exact solutions have been evaluated for velocity, resistance impedance, wall shear stress and
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35

Wang, Fu Jun, Lei Zhang, Lu Wang, et al. "Finite Element Analysis for the Design of Branched Artificial Blood Vessel of Aortic Arch." Applied Mechanics and Materials 302 (February 2013): 550–55. http://dx.doi.org/10.4028/www.scientific.net/amm.302.550.

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In order to set up a curved-shape branch artery-blood coupling model and investigate the effect of the material change in artificial blood vessel on the hemodynamic state, the method of finite element and Fluid Solid Interface in Ansys CFX was used to achieve the structural and fluid analysis with different materials. The displacement of tubular wall was increasing with the young's modulus decrease of material, and the tendency became clear. The von mises stress of the tubular wall is not well-distributed, and the value at the inlet of main artery and branch artery were large. However, at the
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36

TOKUTAKE, Hirotsugu, Kiyotaka IWASAKI, Xiaodong ZHU, and Mitsuo UMEZU. "B207 Strain analysis on a self-expandable Nitinol stent deployed in superficial femoral artery." Proceedings of the JSME Conference on Frontiers in Bioengineering 2015.26 (2015): 113–14. http://dx.doi.org/10.1299/jsmebiofro.2015.26.113.

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37

Fumoto, Toshio, Shouhei Kinoshita, Takao Sasaki, Norihito Shimamura, and Hiroki Ohkuma. "Oxidative Stress Mediates Vascular Tortuosity." Antioxidants 10, no. 6 (2021): 926. http://dx.doi.org/10.3390/antiox10060926.

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Vascular tortuosity is associated with various disorders and is being increasingly detected through advances in imaging techniques. The underlying mechanisms for vascular tortuosity, however, remain unclear. Here, we tested the hypothesis that oxidative stress mediates the generation of tortuous vessels. We used the bilateral common carotid artery (CCA) ligation model to induce vascular tortuosity. Both young and adult rats showed basilar artery tortuous morphological changes one month after bilateral CCA ligation. These tortuous changes were permanent but more pronounced in the adult rats. Mi
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38

TANUMA, Tadashi, Hiroshi OKUDA, Gaku HASHIMOTO, and Anshin ASANO. "2F32 Stress analysis of cerebral artery with an anisotropic multilayer wall model." Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2015.27 (2015): 533–34. http://dx.doi.org/10.1299/jsmebio.2015.27.533.

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39

Akbar, Noreen Sher. "Mixed convection analysis for blood flow through arteries on Williamson fluid model." International Journal of Biomathematics 08, no. 04 (2015): 1550045. http://dx.doi.org/10.1142/s179352451550045x.

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In this paper, the blood flow through a tapered artery with a stenosis by considering axially non-symmetric but radially symmetric mild stenosis on blood flow characteristics is analyzed, assuming the flow is steady and blood is treated as Williamson fluid. The effects of mixed convection heat and mass transfer are also carried out. Perturbation solutions have been calculated for velocity, temperature, concentration, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different types of tapered arteries (i.e. converging tapering, divergi
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Fujimoto, Motoaki, Yasuhiro Shobayashi, Koichiro Takemoto, Satoshi Tateshima, and Fernando Viñuela. "Structural Analysis for Wingspan Stent in a Perforator Model." Interventional Neuroradiology 19, no. 3 (2013): 271–75. http://dx.doi.org/10.1177/159101991301900302.

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Perforator infarction represents a critical problem after intracranial Wingspan stent. To explore the mechanism of perforator infarction, we simulated the stent-artery interaction at an atheromatous plaque with perforator. Structural deformation and biomechanical stress distribution after stenting were analyzed. High radial stress values were located along the stent struts, which surrounded the area with high circumferential stress. Stretched perforator orifice in a circumferential direction after stenting was simulated. These results show that structural deformation could play a role in the m
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Ng, A., P. Pham, J. Vidiac, and D. Y. Leung. "INCREMENTAL VALUE OF TWO-DIMENSIONAL SPECKLE TRACKING STRAIN IMAGING TO WALL MOTION ANALYSIS FOR DETECTION OF CORONARY ARTERY DISEASE IN PATIENTS UNDERGOING DOBUTAMINE STRESS ECHOCARDIOGRAPHY." Heart, Lung and Circulation 18 (January 2009): 10. http://dx.doi.org/10.1016/j.hlc.2009.03.023.

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Ng, Arnold C. T., Marta Sitges, Phuong N. Pham, et al. "Incremental value of 2-dimensional speckle tracking strain imaging to wall motion analysis for detection of coronary artery disease in patients undergoing dobutamine stress echocardiography." American Heart Journal 158, no. 5 (2009): 836–44. http://dx.doi.org/10.1016/j.ahj.2009.09.010.

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43

Shen, X., Y. Q. Deng, S. Ji, H. F. Zhu, J. B. Jiang, and L. X. Gu. "Bending Analysis of Stented Coronary Artery: the Interaction Between Stent and Vessel." Journal of Mechanics 35, no. 4 (2018): 455–63. http://dx.doi.org/10.1017/jmech.2018.23.

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ABSTRACTVessel flexure can be triggered naturally by surgical operation, heart pulsation and body movement. It may affect the mechanical behavior of the stent and the existence of a stent may in turn cause vessel injury. In the present study, the finite element method is employed to study the interaction between stent and vessel during vessel flexure. Two- and four-link stents made of stainless steel 316L and magnesium alloy WE43 are considered. Results indicate that longitudinal deformation of the stent can be caused by vessel flexure, and the higher levels of stress exist in the link struts.
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44

Andova, Valentina, Ljubica Georgievska-Ismail, Elizabeta Srbinovska, and Biljana Janeska. "Does the Presence of Diabetes Mellitus Make a Difference in Pharmacological Stress Echocardiography Outcome Results?" Open Access Macedonian Journal of Medical Sciences 6, no. 11 (2018): 2084–90. http://dx.doi.org/10.3889/oamjms.2018.452.

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BACKGROUND: Coronary artery disease (CAD) is the leading cause of mortality and morbidity in patients with diabetes (DM).
 AIM: Тhe aim of our study was to analyse the ability of pharmacological SE to risk stratify patients with DM using qualitative and quantitative assessment of LV function.
 METHODS: We prospectively assessed 105 consecutive patients (58.7 ± 9.5 y, 39 male) with known or suspected CAD who underwent dipyridamole or dobutamine SE.
 RESULTS: Change of systolic LV function at maximal SE was less pronounced in patients with DM, while parameters of the diastolic fun
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Teferici, Daniela, Spiro Qirko, Elizana Petrela, and Petrit Bara. "Diagnostic Value of 2D Strain Imaging In Patients with Suspected Coronary Artery Disease." Open Access Macedonian Journal of Medical Sciences 2, no. 1 (2014): 46–50. http://dx.doi.org/10.3889/oamjms.2014.008.

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Background: Strain imaging (SI) has been shown to quantify regional myocardial function in both acute ischemic myocardium and infarcted myocardium. The aim of this study is to determine the diagnostic value of SI for the detection of coronary lesions in pts with chest pain, but without apparent wall motion abnormalities. Methods: SI for advanced wall motion analysis was performed in 59 pts with suspicious stable angina (SA) and in 57 pts with suspicious unstable angina (UA), prior to coronary angiography (CAG). Longitudinal strain was measured in 3 apical views. For the identification of ische
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Winston, F. K., L. E. Thibault, and E. J. Macarak. "An Analysis of the Time-Dependent Changes in Intracellular Calcium Concentration in Endothelial Cells in Culture Induced by Mechanical Stimulation." Journal of Biomechanical Engineering 115, no. 2 (1993): 160–68. http://dx.doi.org/10.1115/1.2894116.

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When bovine pulmonary artery endothelial cells in culture are subjected to mechanical strain, their physiology is altered. Experimentally, this mechanical strain is generated by increased tension in the substrate to which the cells are attached and results in altered levels of fibronectin. Studies of the structural response of the endothelial cell suggest that this stimulus is transmitted to the cell membrane, organelles, and cytoskeleton by natural cell attachments in a quantifiable and predictable manner. This report examines altered intracellular calcium homeostasis as a possible messenger
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Mallis, Panagiotis, Dimitrios P. Sokolis, Manousos Makridakis, et al. "Insights into Biomechanical and Proteomic Characteristics of Small Diameter Vascular Grafts Utilizing the Human Umbilical Artery." Biomedicines 8, no. 8 (2020): 280. http://dx.doi.org/10.3390/biomedicines8080280.

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The gold standard vascular substitutes, used in cardiovascular surgery, are the Dacron or expanded polytetrafluoroethylene (ePTFE)-derived grafts. However, major adverse reactions accompany their use. For this purpose, decellularized human umbilical arteries (hUAs) may be proven as a significant source for the development of small diameter conduits. The aim of this study was the evaluation of a decellularization protocol in hUAs. To study the effect of the decellularization to the hUAs, histological analysis was performed. Then, native and decellularized hUAs were biochemically and biomechanic
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Pokhrel, Puskar R., Jeevan Kafle, Parameshwari Kattel, and Hari Prasad Gaire. "Analysis of Blood flow Through Artery with Mild Stenosis." Journal of Institute of Science and Technology 25, no. 2 (2020): 33–38. http://dx.doi.org/10.3126/jist.v25i2.33732.

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Arterial stenosis is an abnormal condition in arteries due to the deposition of fats and other substances, called atherosclerosis. As it restricts the blood flow, it may induce a heart attack. Employing the Navier-Stokes equations, we consider the blood flow in an artery with the presence of a stenosis in an axisymmetric shape. We analyze the blood flow dynamics in cylindrical form by evaluating pressure, pressure drop against the wall, shear stress on the wall. We also analyze the dynamics by evaluating the ratio of pressure drop with stenosis to the pressure drop without stenosis against the
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WANG, XIAOHONG, and XIAOYANG LI. "COMPUTER-BASED MECHANICAL ANALYSIS OF STENOSED ARTERY WITH THROMBOTIC PLAQUE: THE INFLUENCES OF IMPORTANT PHYSIOLOGICAL PARAMETERS." Journal of Mechanics in Medicine and Biology 12, no. 04 (2012): 1250069. http://dx.doi.org/10.1142/s0219519412500698.

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The thrombus is the inappropriate activation of hemostasis in vascular system. In this paper, biomechanical factors affecting the behaviors of artery with intraluminal thrombus were studies. Results indicated that heart rate and blood viscosity had strong impact on the compliance of the stenosis artery and flow pattern. The alteration in blood viscosity had stronger influence than cardiac cycle on the volume change of the fluid region surrounded by thrombus. von Mises stress measured at the thinnest region of the plaque had the largest time-averaged value. The alteration of these parameters co
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Chung, Namsik, Won Heum Shim, Seung Yun Cho, et al. "Segmental Analysis of Thallium-201 Stress Myocardial Perfusion Scanning in Coronary Artery Disease." Korean Circulation Journal 16, no. 4 (1986): 521. http://dx.doi.org/10.4070/kcj.1986.16.4.521.

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