Academic literature on the topic 'Stroke treatments'

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Journal articles on the topic "Stroke treatments"

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KOMOTAR, RICARDO J., and E. SANDER CONNOLLY. "Stroke Treatments." Neurosurgery 55, no. 1 (July 2004): N6. http://dx.doi.org/10.1227/01.neu.0000309434.18777.e1.

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Beresford, Isabel JM, Andrew A. Parsons, and A. Jacqueline Hunter. "Treatments for stroke." Expert Opinion on Emerging Drugs 8, no. 1 (May 2003): 103–22. http://dx.doi.org/10.1517/14728214.8.1.103.

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Haast, Roy AM, Deborah R. Gustafson, and Amanda J. Kiliaan. "Sex Differences in Stroke." Journal of Cerebral Blood Flow & Metabolism 32, no. 12 (October 3, 2012): 2100–2107. http://dx.doi.org/10.1038/jcbfm.2012.141.

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Sex differences in stroke are observed across epidemiologic studies, pathophysiology, treatments, and outcomes. These sex differences have profound implications for effective prevention and treatment and are the focus of this review. Epidemiologic studies reveal a clear age-by-sex interaction in stroke prevalence, incidence, and mortality. While premenopausal women experience fewer strokes than men of comparable age, stroke rates increase among postmenopausal women compared with age-matched men. This postmenopausal phenomenon, in combination with living longer, are reasons for women being older at stroke onset and suffering more severe strokes. Thus, a primary focus of stroke prevention has been based on sex steroid hormone-dependent mechanisms. Sex hormones affect different (patho)physiologic functions of the cerebral circulation. Clarifying the impact of sex hormones on cerebral vasculature using suitable animal models is essential to elucidate male–female differences in stroke pathophysiology and development of sex-specific treatments. Much remains to be learned about sex differences in stroke as anatomic and genetic factors may also contribute, revealing its multifactorial nature. In addition, the aftermath of stroke appears to be more adverse in women than in men, again based on older age at stroke onset, longer prehospital delays, and potentially, differences in treatment.
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Aguiar de Sousa, Diana, Rascha von Martial, Sònia Abilleira, Thomas Gattringer, Adam Kobayashi, Miquel Gallofré, Franz Fazekas, et al. "Access to and delivery of acute ischaemic stroke treatments: A survey of national scientific societies and stroke experts in 44 European countries." European Stroke Journal 4, no. 1 (July 20, 2018): 13–28. http://dx.doi.org/10.1177/2396987318786023.

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Introduction Acute stroke unit care, intravenous thrombolysis and endovascular treatment significantly improve the outcome for patients with ischaemic stroke, but data on access and delivery throughout Europe are lacking. We assessed best available data on access and delivery of acute stroke unit care, intravenous thrombolysis and endovascular treatment throughout Europe. Methods A survey, drafted by stroke professionals (ESO, ESMINT, EAN) and a patient organisation (SAFE), was sent to national stroke societies and experts in 51 European countries (World Health Organization definition) requesting experts to provide national data on stroke unit, intravenous thrombolysis and endovascular treatment rates. We compared both pooled and individual national data per one million inhabitants and per 1000 annual incident ischaemic strokes with highest country rates. Population estimates were based on United Nations data, stroke incidences on the Global Burden of Disease Report. Results We obtained data from 44 European countries. The estimated mean number of stroke units was 2.9 per million inhabitants (95% CI 2.3–3.6) and 1.5 per 1000 annual incident strokes (95% CI 1.1–1.9), highest country rates were 9.2 and 5.8. Intravenous thrombolysis was provided in 42/44 countries. The estimated mean annual number of intravenous thrombolysis was 142.0 per million inhabitants (95% CI 107.4–176.7) and 72.7 per 1000 annual incident strokes (95% CI 54.2–91.2), highest country rates were 412.2 and 205.5. Endovascular treatment was provided in 40/44 countries. The estimated mean annual number of endovascular treatments was 37.1 per million inhabitants (95% CI 26.7–47.5) and 19.3 per 1000 annual incident strokes (95% CI 13.5–25.1), highest country rates were 111.5 and 55.9. Overall, 7.3% of incident ischaemic stroke patients received intravenous thrombolysis (95% CI 5.4–9.1) and 1.9% received endovascular treatment (95% CI 1.3–2.5), highest country rates were 20.6% and 5.6%. Conclusion We observed major inequalities in acute stroke treatment between and within 44 European countries. Our data will assist decision makers implementing tailored stroke care programmes for reducing stroke-related morbidity and mortality in Europe.
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del Zoppo, Gregory. "Antithrombotic Treatments in Acute Ischemic Stroke." Thrombosis and Haemostasis 82, no. 08 (1999): 938–46. http://dx.doi.org/10.1055/s-0037-1615936.

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IntroductionStroke may be defined as a syndrome of thrombohemorrhagic disorders affecting the central nervous system. In this setting, considerable efforts have been directed to improve clinical outcome with antithrombotic agents, including platelet inhibitors, anticoagulants, and plasminogen activators. The search for a role for antithrombotic agents in ischemic stroke rests on the observation that, overall, 75% to 80% of strokes involve thrombotic events. Recent experience with plasminogen activators (PAs) in acute ischemic stroke indicates that, in select patients, clinical improvement is associated with shorter interval from symptom onset to treatment, while clinically significant hemorrhagic transformation increases with delays in treatment. The time-dependence and the subpopulation characteristics of outcomes following PA exposure is entirely compatible with an evolution of brain injury and varies individually, but where microvascular integrity in the ischemic bed decreases with time. These relationships have not been developed or explored with other antithrombotic agents, including antiplatelet agents or anticoagulants. Thus, among antithrombotic agents, only certain PAs have been used in a strictly “acute” setting, that is within 6 to 8 hours of symptom onset. This presentation summarizes current experience with antithrombotic interventions in focal cerebral ischemia in the acute and early (>8) hours following symptom onset.
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Filipska, Karolina, Adam Wiśniewski, and Robert Ślusarz. "Thrombolysis and Mechanical Thrombectomy as Leading Treatments for Acute Ischemic Stroke." Journal of Neurological and Neurosurgical Nursing 8, no. 4 (December 2019): 177–81. http://dx.doi.org/10.15225/pnn.2019.8.4.6.

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Brain vascular diseases, especially strokes, are still a very serious public health and medicine problem. The world is still facing an epidemic of stroke. With the impact load increasing all over the world, there is a continuing need to understand the characteristics of this disease and its impact in different countries. Despite significant improvements in primary prevention and treatment efficacy over the past decades, stroke is still a debilitating disease. Early treatment is the key to successful recovery of patients with ischemic stroke. The aim of the study is to show the most effective methods of treating patients in the acute phase of ischemic stroke. (JNNN 2019;8(4):177–181) Key Words: ischemic stroke, treatment, thrombolysis, thrombectomy
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Al-Senani, Fahmi, Mohammed Al-Johani, Mohammad Salawati, Souda ElSheikh, Maha AlQahtani, Jamal Muthana, Saeed AlZahrani, et al. "A national economic and clinical model for ischemic stroke care development in Saudi Arabia: A call for change." International Journal of Stroke 14, no. 8 (May 23, 2019): 835–42. http://dx.doi.org/10.1177/1747493019851284.

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Background Stroke is a significant burden in Saudi Arabia and the Saudi Ministry of Health's stroke committee has identified an urgent need to improve care. Aim The purpose of this study was to undertake a health-economic analysis to quantify the impact of developing stroke care in the country. Methods An economic model was developed to assess the costs and clinical outcomes associated with an ischemic stroke care development program compared with current stroke care. Based on Saudi epidemiological data, cohorts of ischemic stroke patients enter the model each year for the first 10 years based on increasing incidence. Four treatment options were modeled including reperfusion and non-reperfusion treatments. The development scenario estimates the impact of gradually increasing uptake of more effective treatments over 10 years. Changes in the stroke care organization are considered along with resources required to increase capacity, allowing more patients to be admitted to stroke hospitals and access effective treatments. Results The stroke care development program is associated with an increase in functionally independent patients and a decrease in disabling strokes compared with current stroke care. Additionally, the development program is associated with estimated cost savings of $602 million over 15 years ($255 million direct costs, $348 million indirect costs). Conclusions The model predicts that the stroke care development program is associated with improved patient outcomes and lower overall costs compared with the current stroke care program.
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ZOLER, MITCHEL L. "Intraarterial Treatments Target Acute Stroke." Internal Medicine News 38, no. 22 (November 2005): 35. http://dx.doi.org/10.1016/s1097-8690(05)72366-0.

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Schehr, Robert S. "New treatments for acute stroke." Nature Biotechnology 14, no. 11 (November 1996): 1549–54. http://dx.doi.org/10.1038/nbt1196-1549.

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Markus, Hugh S. "Current treatments in neurology: Stroke." Journal of Neurology 252, no. 3 (March 2005): 260–67. http://dx.doi.org/10.1007/s00415-005-0736-9.

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Dissertations / Theses on the topic "Stroke treatments"

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Lindley, Richard Iain. "Are very large trials of promising treatments for acute stroke feasible?" Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282953.

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Sonde, Lars. "Rehabilitation after stroke : effects of length of stay and treatments to facilitate motor recovery after stroke /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4730-9/.

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Silasi, Gergely, and University of Lethbridge Faculty of Arts and Science. "Novel treatments for inducing cortical plasticity and functional restitution following motor cortex stroke." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2005, 2005. http://hdl.handle.net/10133/278.

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Stroke remains a leading cause of disability in the western world, with symptoms ranging in severity from mild congnitive or motor impairments, to severe impairments in both cognitive and motor domains. Despite ongoing research aimed at helping stroke patients the disease cannot be prevented or cured, therefore a large body of research has been aimed at identifying effective rehabilitative strategies. Based on our understanding of normal brain function, and the meachanisms mediating the limited spontaneous recovery that is observed following injury, factors that promote brain plasticity are likely to be effective treatments for stroke symptoms. The current thesis investigated three novel treatments (COX-2 inhibitor drug, vitamin supplement diet, and social experience) in a rat model of focal ischemia in the motor cortex. All three treatments have been previously shown to alter plasticity in the normal brain, however the current experiments show that the treatments have differential effects following stroke. The COX-2 inhibitors provided limited improvement in functional performance, whereas the vitamin supplement treatment had no effect. Social experience on the other hand was found to block the usually observed spontaneous improvements following the stroke. These results suggest that factors that alter dendritic plasticity may in fact serve as effective stroke treatments depending on the site and the mechanisms whereby the plastic changes are induced.
ix, 149 leaves : ill. ; 29 cm.
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Leach, Kelly Rebecca. "The Use of Forelimb Asymmetry Functional Tests to Determine Motor Recovery With Various Drug Treatments Following Endothelin-Induced Stroke." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1344607995.

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Gibson, Maryika Ivanova. "Effective Strategies for Recognition and Treatment of In-Hospital Strokes." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6756.

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In-hospital onset strokes represent 4% to 20% of all reported strokes in the United States. The variability of treatment protocols and workflows as well as the complex etiology and multiple comorbidities of the in-hospital stroke subpopulation often result in unfavorable outcomes and higher mortality rates compared to those who experience strokes outside of the hospital setting. The purpose of this project was to conduct a systematic review to identify and summarize effective strategies and practices for prompt recognition and treatment of in-hospital strokes. The results of the literature review with leading-edge guidelines for stroke care were corelated to formulate recommendations at an organizational level for improving care delivery and workflow. Peer-reviewed publications and literature not controlled by publishers were analyzed. An appraisal of 24 articles was conducted, using the guide for classification of level of evidence by Fineout-Overholt, Melnyk, Stillwell, and Williamson. The results of this systematic review revealed that the most effective strategies and practices for prompt recognition and treatment of in-hospital strokes included: staff education, creating a dedicated responder team, analysis and improvement of internal processes to shorten the time from discovery to diagnosis, and offering appropriate evidence-based treatments according to acute stroke guidelines. Creating organizational protocols and quality metrics to promote timely and evidence-based care for in-hospital strokes may result in a positive social change by eliminating the existing care disparities between community and in-hospital strokes and improving the health outcomes of this subpopulation of strokes.
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Guillén-Solà, Anna. "Oropharyngeal dysphagia after stroke: assessment and treatment." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/378351.

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Els transtorns de la deglució afecten un 29-67% dels pacients post-Ictus. L’aspiració silent, aspiració sense expressió clínica, afecta del 15-39% dels ictus aguts. La disfàgia pot comportar malnutrició, deshidratació, pneumònia broncoaspirativa i mort, i té impacte sobre els costos sanitaris. L’evidència científica suggereix que la detecció de la disfàgia en estadis precoços de l’ictus redueix el risc de broncoaspiració i és útil per determinar l’estratègia terapèutica. Aquesta tesi avalua la capacitat de dos tests clínics de cribatge, el Mètode d’exploració Clínica de Volum Viscositat (MECV-V) i Test de la tos amb àcid cítric (CCT), per la detecció de l’aspiració i l’aspiració silent, respectivament. El MECV-V consisteix en l’administració de líquid a diferents viscositats i volums sota control de pulsioximetria. Canvis en els signes de seguretat com són el to de veu, la tos durant o després del bolus administrat, la desaturació >3% de la saturació basal, és consideren com a test alterat i al pacient com a possible aspirador. EL CCT registra el número de pics de tos durant el minut d’ inhalació oral d’una solució nebulitzada d’àcid cítric a 1M. Es considera > 5 pics de tos normal, mentre que ≤4 es considera disminuït i al pacient com a baix responedor o possible aspirador silent. En compració ala Videofluoroscòpia (VFSS), el gold estàndard, el MECVV detecta aspiració amb una sensibilitat del 88.2% i una especificitat del 71.4% , mentre que el CCT, detecta aspiració silent amb una sensibilitat i especificitat del 19% i 71%, respectivament. En conclusió el MECVV és un test de baix cost i fàcilment aplicable que compleix els criteris de test de cribatge en població afecte d’ictus; mentre que el CCT, a concentració 1M, no sembla un test útil aplicat individualment per la detecció dels potencials aspiradors silents. S’aporten dades recents sobre un assaig clínic dissenyat per valorar l’efectivitat de dues noves tècniques terapèutiques, l’estimulació elèctrica neuromuscular (NMES) i l’entrenament de la musculatura respiratòria, inspiratòria i espiratòria (IEMT) . Els pacients van ser randomitzats a la logopèdia clàssica (SST) , a NMES i SST o al IEMT i SST. La disfàgia es va avaluar amb el MECV-V i la VFSS, i la força de la musculatura respiratòria també es va recollir. La combinació del NMES o IEMT al SST millora significament els resultats en força respiratòria i els signes de seguretat de la deglució al final de la intervenció. Aquest estudi aporta noves evidències sobre teràpies emergents en el tractament de la disfàgia.
Swallowing disorders affect up to 29-67% of patients with stroke. Silent aspiration, aspiration without clinical signs expression, is present in 15-39% of acute stroke samples. Dysphagia can lead to malnutrition, dehydration, bronchoaspirative pneumonia and death, and have impact on health care costs. Available evidence suggests that screening dysphagia in the early stages of stroke onset reduces the risk of bronchoaspiration and is useful to determine the best therapeutic strategy. This thesis project is aimed to evaluate two different screening techniques, the Volume Viscosity Swallow Test (V-VST) and the Citric Cough Test (CCT), for detecting aspiration and silent aspiration, respectively. The V-VST consists of the administration of different liquid viscosities and food consistencies under pulse oximetry control. Changes in security signs as tone of voice, coughing during or after eating, or desaturation of more than 3% compared to baseline oxygen saturation, are considered as a failed test and classifies the patient as potential aspirator or no aspirator. The CCT records the number of cough peaks in the minute to the oral inhalation of a 1M mixture of saline and citric acid through an ultrasonic nebulizer. More than 5 cough peaks are considered as normal responders, whereas those with ≤4 are considered as reduced or absent responders. In comparison with the videofluoroscopic swallow study (VFSS), the gold standard, the V-VST detects aspiration with a sensitivity of 88.2% and specificity of 71.4%, whilst the CCT detects silent aspiration with sensitivity and specificity indexes of 19% and 71%, respectively. In conclusion, the V-VST is low in cost, easy to use and very sensitive, meeting the requirements of oropharyngeal dysphagia and aspiration screening test in subacute stroke; whilst the low sensitivity of the CCT using 1.0% (weight by volume) does not support its use as standalone tool to screen for silent aspiration in stroke patients. In addition, breaking results of a clinical trial aimed to determine effectiveness of two new therapeutic techniques, neuromuscular electrical stimulation (NMES) and inspiratory and expiratory muscle training (IEMT), are discussed. Patients were randomly assigned to standard swallow therapy (SST), IEMT and SST, NMES and SST. Dysphagia was assessed with the V-VST and VFSS, and respiratory muscle strength parameters were also recorded. The combination of IEMT or NMES to the SST was associated with significantly improved respiratory strength and better pharyngeal security. This study provides new evidences on emerging strategies to manage dysphagia
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Ajmo, Craig T. "Alternative targets for the treatment of stroke." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0002114.

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Winkens, Ieke. "Mental slowness after stroke assessment and treatment /." [Maastricht : Maastricht : Maastricht University] ; University Library, Universiteit Maastricht [host], 2009. http://arno.unimaas.nl/show.cgi?fid=15083.

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Ajmo, Craig T. Jr. "Alternative Targets for the Treatment of Stroke." Scholar Commons, 2007. https://scholarcommons.usf.edu/etd/594.

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Stroke is cerebrovascular injury that has been reported to be the third leading cause of death and the first leading cause of disability in the world (W. H.O. 2007). Currently, there is only one FDA approved treatment for stroke which is recombinant tissue plasminogen activator. This treatment has a narrow therapeutic window of three hours after ischemic stroke and can adversely cause the production of oxygen free radicals and intracranial hemorrhage. These limitations result in only 2-3% of all stroke victims as being candidates for this therapy as many patients do not arrive at the hospital in time to receive treatment, are not properly diagnosed, or do not know that they have had a stroke within this three hour time period. The purpose of these experiments was to elucidate alternative targets of stroke for the benefit of developing new treatments that stimulate neuroprotective and anti-inflammatory effects at the site of injury. It has been shown that transfusion of human umbilical cord blood cells up to 48 hours after stroke significantly reduces infarction and we have examined other targets that mimic these effects. We have shown that sigma receptor activation by DTG, a high affinity universal sigma agonist, reduces infarct volume when administered 24 hours after stroke. This suggests that modulation of neurodegenerative and inflammatory responses can extend the therapeutic window of treatment. For the first time, evidence is provided that shows that the spleen enhances the neurodegeneration caused by stroke as splenectomy prior to stroke profoundly decreased infarction volume. Finally, we studied signaling mechanisms of the splenic reaction to stroke and determined that this response is not directly dependent on neurotransmission via the splenic nerve. Denervation of the spleen prior to stroke showed no changes in neurodegenerative load at the site of injury in rat brains when compared to those subjected to stroke only. Overall, these experiments provide evidence showing that targets mediating neuroprotective and anti-inflammatory effects can lead to novel therapeutic interventions of stroke.
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Kleven, Robert T. "Transcranial Ultrasound for the Treatment of Stroke." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595848922517413.

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Books on the topic "Stroke treatments"

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Tsiskaridze, Alexander, Arne Lindgren, and Adnan Qureshi, eds. Treatment-Related Stroke. Cambridge: Cambridge University Press, 2016. http://dx.doi.org/10.1017/cbo9781139775397.

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Yatsu, Frank M. Stroke. London: Arnold, 1992.

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Lee, Seung-Hoon, ed. Stroke Revisited: Diagnosis and Treatment of Ischemic Stroke. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-1424-6.

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Stroke. Detroit: Greenhaven Press, 2012.

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Williamson, C. J. Stroke: Self help & home treatment. Fakenham: Rehabilitation Publications, 1997.

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Walkey, Marilyn M. Acupuncture treatment of acute stroke. Portland, Or: NCNM, 2007.

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R, Caplan Louis, ed. Stroke essentials. 2nd ed. Sudbury, MA: Physicians' Press, 2010.

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C, Grotta James, and Pettigrew L. Creed, eds. Stroke: 100 maxims. London: E. Arnold, 1995.

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Interventional stroke therapy. New York: Thieme, 2013.

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Manifestations of stroke. Basel: Karger, 2012.

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Book chapters on the topic "Stroke treatments"

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Chou, Daisy, Anja Muehle, Paul A. Lapchak, and Ali Khoynezhad. "Rabbit Spinal Cord Ischemia Model for the Development of Neuroprotective Treatments." In Springer Series in Translational Stroke Research, 689–700. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-45345-3_29.

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De Keyser, J., G. Ramsaransing, E. Zeinstra, and N. Wilczak. "Neuroprotection in Acute Ischemic Stroke: Lessons for Early Treatment in Multiple Sclerosis." In Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis, 109–14. Milano: Springer Milan, 2004. http://dx.doi.org/10.1007/978-88-470-2117-4_10.

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Gandolfo, Caterina, and Amerigo Stabile. "Hot Topics in TAVI: Paravalvular Leak, Thrombosis, PM Implantation, Stroke, Durability." In Advances in Treatments for Aortic Valve and Root Diseases, 349–57. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-66483-5_24.

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Akins, P. T., and C. Y. Hsu. "Future Directions in Research and Development of New Treatments for Ischemic Stroke." In Monographs in Clinical Neuroscience, 151–62. Basel: KARGER, 1997. http://dx.doi.org/10.1159/000061577.

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Ferrante, Simona, Marta Gandolla, Elisabetta Peri, Emilia Ambrosini, and Alessandra Pedrocchi. "RCT Design for the Assessment of Rehabilitation Treatments: The Case Study of Post-stroke Rehabilitation." In Advanced Technologies for the Rehabilitation of Gait and Balance Disorders, 29–45. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72736-3_2.

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Kramer, Andreas H. "Treatment of Hemorrhagic Stroke." In Stroke, 78–102. Oxford: John Wiley & Sons, 2013. http://dx.doi.org/10.1002/9781118560730.ch5.

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Antonios, Nader, and Scott Silliman. "Treatment of Acute Ischemic Stroke." In Stroke, 37–54. Oxford: John Wiley & Sons, 2013. http://dx.doi.org/10.1002/9781118560730.ch3.

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Ueda, Toshihiro, Tatsuro Takada, Noriko Usuki, Satoshi Takaishi, Yoshiaki Tokuyama, Kentaro Tatsuno, Yuki Hamada, and Tomohide Yoshie. "Outcomes of Balloon Angioplasty and Stenting for Symptomatic Intracranial Atherosclerotic Stenosis at a High Volume Center." In Acta Neurochirurgica Supplement, 63–67. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63453-7_9.

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AbstractPurpose: This study investigated the periprocedural complication rates, long-term outcome, and restenosis of endovascular treatment for intracranial atherosclerotic stenosis (ICS) at our hospital.Methods: We retrospectively analyzed the clinical data of 217 patients comprising 256 endovascular treatments for high-grade symptomatic ICS. The lesion was located in the internal carotid artery in 77, the middle cerebral artery in 111, the basilar artery in 29, and the vertebral artery in 39. Patients were divided into two groups, before (early-phase group, 1999–2013) and after approval of Wingspan (late-phase group, 2014–2017).Results: In the early-phase group (n = 163), 157 lesions were treated by balloon angioplasty and 31 (17%) by coronary stenting. In the late-phase group (n = 54), 33 lesions were treated by balloon angioplasty and 35 (52%) by Wingspan stenting. Overall technical success rates were 96% in the balloon angioplasty and 100% in stenting groups. The 30-day rate of stroke, TIA, and death were 4.8% in the early-phase group and 4.4% in the late-phase group. There was one minor stroke and two TIAs during the follow-up period in the late-phase group.Conclusions: Endovascular treatment for symptomatic ICS in this study appeared to be safe and effective if patients are properly selected. However, future well-designed randomized trials with different techniques and modified patients selection criteria are certainly warranted.
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Weber, R., and H. C. Diener. "Secondary Stroke Prevention – Medical Treatment." In Stroke, 144–59. Basel: KARGER, 2009. http://dx.doi.org/10.1159/000210280.

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Prentice, Howard, Payam M. Gharibani, Zhiyuan Ma, Anamaria Alexandrescu, Rafaella Genova, Po-Chih Chen, Jigar Modi, et al. "Neuroprotective Functions Through Inhibition of ER Stress by Taurine or Taurine Combination Treatments in a Rat Stroke Model." In Advances in Experimental Medicine and Biology, 193–205. Dordrecht: Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-024-1079-2_17.

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Conference papers on the topic "Stroke treatments"

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Santorelli, Adam, Sean Fitzgerald, Andrew Douglas, Karen Doyle, and Martin O'Halloran. "Dielectric profile of blood clots to inform ischemic stroke treatments*." In 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society. IEEE, 2020. http://dx.doi.org/10.1109/embc44109.2020.9175387.

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Chumacero-Polanco, Erik A., and James Yang. "Fall Prevention Therapies for Individuals With Stroke: A Survey." In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-67456.

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Stroke basically consists in brain-cells death due to lack or excess of blood. Stroke has many important consequences and falls are one of the most concerning. Falls can produce several injures from minor lacerations to fractures and death. It has been found that balance and gait impairments after stroke are important risk factors for fall. Hence, improving balance and gait ability in stroke survivors can significantly reduce falls rate. In this literature review, we review the main characteristic and the therapeutic results of different therapeutic interventions aimed at improving balance and walking ability. The main therapeutic interventions included are the Bobath therapy, exercise-based interventions, orthotic and assistive devices, modality treatments, alternative therapies, robotic-assisted training, and computational-based interventions. The parameters considered as evidence of balance and/or gait recovery after a specific intervention are: walking speed (WS), cadence, endurance, stride/step length, weight/walking symmetry, and sway. Our main findings are: 1) The wide use of the Bobath concept is not well supported by evidence due to its performance has been found to be inferior to some exercises-based interventions such as walking training; 2) exercises-based interventions were classified as strength and task-specific training. The former improves muscular and bone health, aerobic capability, and prepares the patient to perform a more demanding activity. The latter is designed as a repetitive training of a functional activity, mainly walking, and sit to stand exercises, which improve both gait and balance. Orthotic and assistive devices have effects on balance and gait but only while they are worn or used; 3) robotic assisted walking-training presented similar results to overground or treadmill walking training in terms of walking speed and balance recovery. However, the most important advantage lies on the reduction of burden for therapists; 4) thee most important use of motion analysis is as a tool for identify the causes deficits in a patient and the to design a therapy in accordance; 5) motion synthesis can be used as a tool to answer very specific questions related to capabilities/limitations of a patient. For instance, “what would be the effect of increasing hip-torque capability of a stroke survivor on the walking-symmetry?” The answer to this question would either help to design an exercise/intervention or to discard such intervention due to low impact; 6) some treatments are added to a main therapy to increase its effect on a given parameter. Functional electrical stimulation, which is added to cycling training to improve motion patterns. Biofeedback is used during balance training to reduce weight-asymmetry. And virtual reality and video games are used to increase motivation and permanence of patient on a therapy; 7) we found some alternative or no widely used therapies. Among the most promising we can mention Tai-Chi exercises, which integrates physical and mental activities to improve balance and gait and rhythmic auditory stimulation that improves WS and weight-symmetry; and 8) orthotics devices help to reduce falls by extending the base of support but the effect appears only while they are worn. In general, there is not an ultimate therapy able to fit to every patient. The choice should depend on patient’s goals and conditions. Moreover, falls can not be eliminated but they can be substantially reduced by improving balance and gait.
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Fregly, Benjamin J., Yi-Chung Lin, Jonathan P. Walter, Justin W. Fernandez, Scott A. Banks, and Marcus G. Pandy. "Simultaneous Prediction of Muscle and Contact Forces in the Knee During Gait." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-205543.

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Walking is important for human health, and independent ambulation predicts quality of life [1]. The study and treatment of neurological and joint disorders that inhibit walking would be more effective if muscle and joint forces could be determined reliably for individual patients. Knowledge of muscle forces is needed to characterize muscle coordination, which is a factor in neurological disorders such as cerebral palsy and stroke, while knowledge of joint contact forces is needed to characterize articular loading, which is a factor in bone and joint disorders such as osteoporosis and osteoarthritis. Reliable determination of these internal forces for individual patients would facilitate the design of customized surgical and rehabilitation treatments that maximize functional outcome.
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Mulvihill, J. J., E. M. Cunnane, E. Kavanagh, and M. T. Walsh. "Experimental Determination of the Mechanical and Biological Properties of Carotid Artery Plaques." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14693.

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Atherosclerosis is a cardiovascular disease that occurs within the walls of arteries and can result in a reduction of the lumen diameter. This reduction can cause a decrease in blood flow to the brain which can lead to a stroke event. Carotid angioplasty stenting (CAS) is a minimally invasive surgical treatment for stroke prevention and has been found to show equivalency to the highly invasive open artery repair which is a more commonly used surgical technique (Brott et al. 2010). Development in the design of stent and angioplasty devices is necessary for the continuous improvement of minimally invasive treatments of carotid artery disease. However, a major concern with regard to this treatment is the rupture of the plaque due to the almost instantaneous inflation of the stent device. To further improve the design of these devices a better understanding of the mechanical behaviour and failure of the plaque during minimally invasive treatment in the circumferential direction is required. A limited amount of data exists regarding the mechanical behaviour of atherosclerotic plaques under physiological conditions. Studies undertaken by Maher et al. (2009) and Teng et al. (2009) have tested the tensile properties of the plaque in the circumferential direction but these studies employed unphysiological strain rates which limit the true representation of the global properties of the plaque. This current study aims to biologically and mechanically characterise the whole plaque tissue and to determine if a correlation exists between the mechanical behaviour and the pre-operatively identified biological content of the plaque.
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John, Chand T., Melanie D. Fox, May Q. Liu, Michael H. Schwartz, and Scott L. Delp. "Muscle Contributions to Medial-Lateral Acceleration of the Body During Walking." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206716.

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Control of lateral balance during walking can be hindered by aging, stroke, or neuromuscular impairments [1, 2, 3]. Lateral balance can be characterized using the medial-lateral acceleration of the mass center of the body, yet the mechanisms by which muscles coordinate medial-lateral acceleration of the body mass center during walking are poorly understood. Elucidation of these mechanisms could help improve rehabilitative or surgical treatments for improving lateral balance in patients with walking impairments. For example, if the muscles that contributed most to medial-lateral acceleration of the body mass center were known, strengthening these muscles could be the focus of therapy. In this study, we analyzed a three-dimensional, muscle-driven simulation of unimpaired walking to quantify the contributions of individual muscles to the medial-lateral acceleration of the body mass center.
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Lee, Namheon, Ashish Das, William M. Gottliebson, and Rupak K. Banerjee. "Assessment of Right Ventricular Inefficiency Using Energy Transfer Ratio in Repaired Tetralogy of Fallot." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53965.

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Pulmonary insufficiency (PI) induces pulmonary regurgitation and often leads to right ventricular (RV) enlargement and RV pressure overloading in repaired Tetralogy of Fallot (rTOF) patients. The appropriate timing of surgical treatments to renormalize RV function remains uncertain due to lack of suitable clinical diagnostic parameters. An energy transfer ratio (eMPA) between the net energy (Enet) transferred at main pulmonary artery (MPA) from RV and stroke work (SW) by RV was calculated using RV volume and pressure data for subjects in two study groups: the rTOF patient group (n = 7) and the control group (n = 7). Statistical analysis was performed to determine the difference of eMPA between the two groups. The mean eMPA for rTOF patients (0.64) was significantly lower (60.2%, p<0.05) than that of controls (1.61).
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Wang, Lulu, Ahmed Al-Jumaily, and Ray Simpkin. "Antenna Array Configuration in Holographic Microwave Imaging." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-36556.

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Biomedical imaging has played an important role in identifying and monitoring the effectiveness of the current state of the art treatments for many diseases. We recently proposed a novel holographic microwave imaging array (HMIA) technique for lesion detection. One of the most important considerations of this technique is the antenna array configuration. This paper demonstrates investigation of using various antenna array configurations to generate a high-resolution microwave image by using the HMIA technique. Both simulation and experimental results are obtained and compared using spiral, random and regularly spaced array configurations to fully demonstrate the effectiveness of antenna arrays to the HMIA technique. The results show that the proposed spiral and random array configurations have the ability to produce high-resolution images at significantly lower cost compared to regularly spaced array. The potential biomedical imaging applications of the research findings would be breast cancer detection and/or brain stroke detection.
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Watkinson, J., F. Austein, O. Jansen, and F. Wodarg. "Fast Stroke Treatment without Microcatheter and Wire." In 100. Deutscher Röntgenkongress. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0037-1682258.

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Chueh, J. Y., A. K. Wakhloo, and M. J. Gounis. "Mechanical Flow Restoration in Acute Ischemic Stroke: A Model System of Cerebrovascular Occlusion." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53172.

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Stroke is the leading cause of disability and the third cause of death in the United States. About 20% of acute ischemic strokes (AIS) are caused by a large artery occlusion, and restoration of blood flow in a reasonable time is the principle goal of treatment. FDA-approved recombinant tissue plasminogen activator (tPA) administration for treatment of stroke is efficacious, but it has short treatment time window and risk of symptomatic hemorrhage that result in only 3–5% patients of who receive this treatment. Alternatively, endovascular treatment using thrombectomy devices, MERCI and Penumbra systems, has been cleared by the FDA. Without adjunctive therapies, the recanalization rate and clinical outcome associated with these devices could be improved.
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Maitland, Duncan J., Mariel Triggs, Steven R. Visuri, Abraham Lee, Richard London, and Luiz Da Silva. "Lasers in the photo-mechanical treatment of stroke." In Biomedical Topical Meeting. Washington, D.C.: OSA, 1999. http://dx.doi.org/10.1364/bio.1999.ctub1.

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Reports on the topic "Stroke treatments"

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Hernandez, Adrian, Emily O’Brien, Ying Xian, Eric Peterson, DaiWai Olson, Gregg Fonarow, and Lee Schwamm. Comparing Different Treatments for People Who Have Had a Stroke—The PROSPER Study. Patient-Centered Outcomes Research Institute (PCORI), September 2020. http://dx.doi.org/10.25302/09.2020.ce.13047073.

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Basu, Sayani. Nanoparticle-Based Therapeutics for the Treatment of Stroke. Nature Library Ltd, November 2020. http://dx.doi.org/10.47496/nl.blog.13.

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Fitch, J. P. Technologies for diagnosis and treatment of acute stroke. Office of Scientific and Technical Information (OSTI), February 1998. http://dx.doi.org/10.2172/654334.

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Yang, Yaqin, X. He, J. Dai, D. Kong, Y. Mu, and C. Wang. The curative effect and security of the massage treatment of Post-stroke Intractable hiccup. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2021. http://dx.doi.org/10.37766/inplasy2021.3.0069.

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Zong, Long-ze, Li Ma, and Ying-ying Liu. Arthroscopic capsular release for the treatment of post-stroke frozen shoulder: a protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0128.

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Li, Ruo-Yang, Rui-Jue Huang, Ke-Yu Chen, and Qian Yu. Comparison of multiple acupoints combination in the treatment of Post-stroke Cognitive Impairment:a network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2021. http://dx.doi.org/10.37766/inplasy2021.3.0054.

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He, Kelin, Xinyun Li, Bei Qiu, Yi Huang, Qinqin Chen, and Ruijie Ma. Comparative efficacy of different acupuncture treatment for post-stroke dysphagia:A protocol for Bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0105.

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Pennebaker, F. M. Evaluation of Warm Acid Strike Treatment for Silicon Analysis in High Level Waste. Office of Scientific and Technical Information (OSTI), March 2003. http://dx.doi.org/10.2172/809094.

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Doyle, F. M., and D. L. Bodine. Treatment of aqueous streams containing strong oxidants using bituminous coal. Office of Scientific and Technical Information (OSTI), December 1995. http://dx.doi.org/10.2172/206445.

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Cao, Genmao. Safety of glycoprotein IIb-IIIa inhibitors used in acute ischemic stroke treatment: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review Protocols, April 2020. http://dx.doi.org/10.37766/inplasy2020.4.0150.

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