Log in

Relevant bibliographies by topics / Stroke treatments / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Stroke treatments.

Dissertations / Theses on the topic 'Stroke treatments'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Stroke treatments.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Lindley, Richard Iain. "Are very large trials of promising treatments for acute stroke feasible?" Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282953.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Sonde, Lars. "Rehabilitation after stroke : effects of length of stay and treatments to facilitate motor recovery after stroke /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4730-9/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Silasi, Gergely, and University of Lethbridge Faculty of Arts and Science. "Novel treatments for inducing cortical plasticity and functional restitution following motor cortex stroke." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2005, 2005. http://hdl.handle.net/10133/278.

Full text

Abstract:

Stroke remains a leading cause of disability in the western world, with symptoms ranging in severity from mild congnitive or motor impairments, to severe impairments in both cognitive and motor domains. Despite ongoing research aimed at helping stroke patients the disease cannot be prevented or cured, therefore a large body of research has been aimed at identifying effective rehabilitative strategies. Based on our understanding of normal brain function, and the meachanisms mediating the limited spontaneous recovery that is observed following injury, factors that promote brain plasticity are li

APA, Harvard, Vancouver, ISO, and other styles

4

Leach, Kelly Rebecca. "The Use of Forelimb Asymmetry Functional Tests to Determine Motor Recovery With Various Drug Treatments Following Endothelin-Induced Stroke." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1344607995.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Gibson, Maryika Ivanova. "Effective Strategies for Recognition and Treatment of In-Hospital Strokes." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6756.

Full text

Abstract:

In-hospital onset strokes represent 4% to 20% of all reported strokes in the United States. The variability of treatment protocols and workflows as well as the complex etiology and multiple comorbidities of the in-hospital stroke subpopulation often result in unfavorable outcomes and higher mortality rates compared to those who experience strokes outside of the hospital setting. The purpose of this project was to conduct a systematic review to identify and summarize effective strategies and practices for prompt recognition and treatment of in-hospital strokes. The results of the literature rev

APA, Harvard, Vancouver, ISO, and other styles

6

Guillén-Solà, Anna. "Oropharyngeal dysphagia after stroke: assessment and treatment." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/378351.

Full text

Abstract:

Els transtorns de la deglució afecten un 29-67% dels pacients post-Ictus. L’aspiració silent, aspiració sense expressió clínica, afecta del 15-39% dels ictus aguts. La disfàgia pot comportar malnutrició, deshidratació, pneumònia broncoaspirativa i mort, i té impacte sobre els costos sanitaris. L’evidència científica suggereix que la detecció de la disfàgia en estadis precoços de l’ictus redueix el risc de broncoaspiració i és útil per determinar l’estratègia terapèutica. Aquesta tesi avalua la capacitat de dos tests clínics de cribatge, el Mètode d’exploració Clínica de Volum Viscositat (M

APA, Harvard, Vancouver, ISO, and other styles

7

Ajmo, Craig T. "Alternative targets for the treatment of stroke." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0002114.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Winkens, Ieke. "Mental slowness after stroke assessment and treatment /." [Maastricht : Maastricht : Maastricht University] ; University Library, Universiteit Maastricht [host], 2009. http://arno.unimaas.nl/show.cgi?fid=15083.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Ajmo, Craig T. Jr. "Alternative Targets for the Treatment of Stroke." Scholar Commons, 2007. https://scholarcommons.usf.edu/etd/594.

Full text

Abstract:

Stroke is cerebrovascular injury that has been reported to be the third leading cause of death and the first leading cause of disability in the world (W. H.O. 2007). Currently, there is only one FDA approved treatment for stroke which is recombinant tissue plasminogen activator. This treatment has a narrow therapeutic window of three hours after ischemic stroke and can adversely cause the production of oxygen free radicals and intracranial hemorrhage. These limitations result in only 2-3% of all stroke victims as being candidates for this therapy as many patients do not arrive at the hospital

APA, Harvard, Vancouver, ISO, and other styles

10

Kleven, Robert T. "Transcranial Ultrasound for the Treatment of Stroke." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595848922517413.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Ali, Khalid Mustafa. "Stroke and oxygen: research relating to acute, stroke, hypoxia, assessment, treatment and study design." Thesis, Keele University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487905.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Wallace, A. C. "Recovering hand function after stroke : mechanisms and treatment." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1344098/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Maniskas, Michael E. "LOOKING TO THE FUTURE OF STROKE TREATMENT: COMBINING RECANALIZATION AND NEUROPROTECTION IN ACUTE ISCHEMIC STROKE." UKnowledge, 2016. http://uknowledge.uky.edu/neurobio_etds/17.

Full text

Abstract:

Stroke is the 5th leading cause of death in the U.S. with 130,000 deaths and around 800,000 affected annually. Currently, there is a significant disconnect between basic stroke research and clinical stroke therapeutic needs. Few animal models of stroke target the large vessels that produce cortical deficits seen in the clinical setting. Also, current routes of drug administration, intraperitoneal and intravenous, do not mimic the clinical route of intra-arterial drug administration. To bridge this divide, we have retro-engineered a mouse model of stroke from the current standard of care for em

APA, Harvard, Vancouver, ISO, and other styles

14

Lendrem, Wendy. "Clinical decision analysis and the selection of aphasic patients for active treatment." Thesis, University of Newcastle Upon Tyne, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387357.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Mahler, Leslie Ann. "Intensive behavioral voice treatment of dysarthria secondary to stroke." Diss., Connect to online resource, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3239406.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Yu, Xinge. "Stroke Study: Novel Animal Models and Innovative Treatment Strategy." Ohio University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1450735023.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Dahllöf, Oliver, Oliver Dahllöf, Felix Hofwimmer, and Felix Hofwimmer. "Optimal placement of a Mobile Stroke Unit (MSU) to achieve improved stroke care." Thesis, Malmö universitet, Fakulteten för teknik och samhälle (TS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20525.

Full text

Abstract:

Tid till behandling är livsviktigt för människor som får en stroke. På olika platser i världen har man därför sett värdet i att införskaffa en specialambulans för stroke (stroke-ambulans) som har specialutrustning och specialpersonal som kan utföra intravenös behandling (trombolys). Då det är uppenbart att dess involvering i vården skulle hjälpa åtminstone en viss andel patienter används ofta ingen utvecklad metod eller analys av var och hur denna stroke-ambulans ska placeras. Genom att noggrant undersöka läget i Skåne län om hur denna placeringen kan gå till, är vårt mål att genom vår metod,

APA, Harvard, Vancouver, ISO, and other styles

18

Thompson, Douglas David. "Predicted risk of harm versus treatment benefit in large randomised controlled trials." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15843.

Full text

Abstract:

Most drugs come with unwanted, and perhaps harmful, side-effects. Depending on the size of the treatment benefit such harms may be tolerable. In acute stroke, treatment with aspirin and treatment with alteplase have both proven to be effective in reducing the odds of death or dependency in follow-up. However, in both cases, treated patients are subject to a greater risk of haemorrhage – a serious side-effect which could result in early death or greater dependency. Current treatment licenses are restricted so as to avoid treating those with certain traits or risk factors associated with bleedin

APA, Harvard, Vancouver, ISO, and other styles

19

Smith, Melissa. "The experiences and perceptions of individuals with stroke about the usefulness of the model of occupational self efficacy in a rural setting." University of the Western Cape, 2019. http://hdl.handle.net/11394/6923.

Full text

Abstract:

Magister Scientiae (Occupational Therapy) - MSc(OT)<br>Individuals diagnosed with stroke particularly in rural communities have a poor return to work rate. Vocational rehabilitation has been used as an intervention strategy with various types of clients with disability or injury in order to improve their work skills. The aim of the proposed study is to describe the experiences and perceptions of individuals diagnosed with stroke about the usefulness of the Model of Occupational Self Efficacy in assisting them in returning to their worker role particularly in a rural setting. Eight participants

APA, Harvard, Vancouver, ISO, and other styles

20

Knapp, Frances Elizabeth. "Social power dynamics and partnership in stroke physiotherapy treatment interactions." Thesis, University of Southampton, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440414.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Wardlaw, Joanna Marguerite. "Imaging and treatment of acute ischaemic stroke : the application and verification of non-invasive imaging techniques in the investigation and treatment of acute ischaemic stroke." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/20860.

Full text

Abstract:

The purpose of the project which led to the writing of this thesis was to: 1) Establish the accuracy, limitations and practicality of a simple isotope test, the mean Cerebral Transit Time (MCTT), developed in the Western General Hospital, Edinburgh, and its ability to diagnose the pattern of cerebral arterial occlusion in acute ischaemic stroke; 2) Study the effect of early reperfusion of the cerebral infarct on swelling of the infarct in the acute stage, and clinical outcome in patients with symptoms of extensive acute cerebral ischaemia; 3) Perform an overview analysis of thrombolytic therap

APA, Harvard, Vancouver, ISO, and other styles

22

Askim, Torunn. "Recovery after stroke - assessment and treatment; with focus on motor function." Doctoral thesis, Norwegian University of Science and Technology, Department of Public Health and General Practice, 2008. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2089.

Full text

Abstract:

<p>The incidence of stroke has not changed significantly in recent decades. However, the actual number of strokes is likely to increase as a consequence of the increasing number of elderly people, creating a significant burden on the health care system, the patients and their families. Pareses are the most common impairment reported after stroke. Motor impairments are associated with reduced self-perceived health, and consequently rehabilitation after stroke has a strong emphasis on physiotherapy and motor training. However, more knowledge about motor recovery and effects of therapy is needed

APA, Harvard, Vancouver, ISO, and other styles

23

Martinsson, Louise. "Facilitation of recovery after ischaemic stroke : early dexamphetamine and physiotherapy treatment /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-668-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Gallacher, Katie I. "An exploration of treatment burden and patient capacity in people with stroke." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7736/.

Full text

Abstract:

Background and aims: Advances in modern medicine have led to improved outcomes after stroke, yet an increased treatment burden has been placed on patients. Treatment burden is the workload of health care for people with chronic illness and the impact that this has on functioning and well-being. Those with comorbidities are likely to be particularly burdened. Excessive treatment burden can negatively affect outcomes. Individuals are likely to differ in their ability to manage health problems and follow treatments, defined as patient capacity. The aim of this thesis was to explore the experience

APA, Harvard, Vancouver, ISO, and other styles

25

Rushing, Jessica L. "EVIDENCE-BASED MUSIC THERAPY TREATMENT TO ELEVATE MOOD DURING ACUTE STROKE CARE." UKnowledge, 2019. https://uknowledge.uky.edu/rehabsci_etds/54.

Full text

Abstract:

Stroke is the fifth leading cause of death in the U.S. with approximately 795,000 Americans experiencing a stroke each year. In addition to common difficulties with communication and physical impairments following stroke, psychosocial impacts warrant assessment and treatment. Experiencing a stroke can lead to depression, mood disorders, and difficulties with emotion regulation. It is well documented that post-stroke depression (PSD) affects a third of stroke survivors. Higher levels of depression and depressive symptoms are associated with a less efficient use of rehabilitation services, poor

APA, Harvard, Vancouver, ISO, and other styles

26

Hagerty, Kailyn M. "Comparing Two Different Statins in a Delayed Pharmacological Treatment for Ischemic Stroke." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1341957043.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Chua, Eldrich Norwin Siy, and 蔡季延. "The effects of noninvasive brain stimulation on cognitive function in patients with stroke : a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206919.

Full text

Abstract:

Introduction: Cognitive impairments occur frequently in stoke survivors, yet current conventional post-stroke care focuses mainly on motor function. Transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) are noninvasive brain stimulation techniques (NIBS) that are used in neurological rehabilitation. Its efficacy is well-established in motor recovery post-stroke, but research on its effects on the associated cognitive decline after stroke is fairly new. The aim of this review is to evaluate recent studies and provide a summary on the effects of N

APA, Harvard, Vancouver, ISO, and other styles

28

Lennermo, Linnéa. "Att drabbas av stroke : En litteraturstudie baserad på självbiografier." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-18372.

Full text

Abstract:

Bakgrund: Stroke innebär blödning eller propp i något eller några av hjärnans blodkärl och är en sjukdom som drabbar många människor världen över varje dag. Insjuknande i stroke kan medföra både fysiska och psykiska funktionsnedsättningar och kan således ha stora konsekvenser för den drabbade individen. Ökad kunskap kring upplevelser av att insjukna i stroke kan hjälpa sjuksköterskan att ge god och specifik omvårdnad, vilket kan vara avgörande för patientens hälsa och välbefinnande. Syfte: Att beskriva människors upplevelser av att drabbas av stroke. Metod: En litteraturstudie där sex självbio

APA, Harvard, Vancouver, ISO, and other styles

29

Michou, Emilia. "Mechanisms and therapeutic application of neurostimulation in the treatment of dysphagia after stroke." Thesis, University of Manchester, 2010. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:136896.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Edmans, Judith Alison. "A comparison of two approaches in the treatment of perceptual problems after stroke." Thesis, University of Nottingham, 1999. http://eprints.nottingham.ac.uk/14194/.

Full text

Abstract:

Perceptual problems are common following stroke and affect the patients' functional ability, suggesting that these problems should be treated. Eighty patients admitted to the Nottingham Stroke Unit, were assessed for perceptual and functional abilities, using standardised assessments (Rivermead Perceptual Assessment Battery, Barthel ADL Index and Edmans ADL index). Each patient identified as having perceptual problems, was randomly allocated to one of two groups for perceptual treatment. One group followed the transfer of training approach and one group followed the functional approach. The st

APA, Harvard, Vancouver, ISO, and other styles

31

McCulloch, Hollis. "Fabrication and Characterization of Composite Membranes as Drug-Delivering Duraplasty for Stroke Treatment." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39156.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Malhotra, Konark, Jason J. Chang, Arjun Khunger, et al. "Minocycline for acute stroke treatment: a systematic review and meta-analysis of randomized clinical trials." Dr. Dietrich Steinkopff Verlag GmbH and Co. KG, 2018. http://hdl.handle.net/10757/624615.

Full text

Abstract:

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.<br>Background: Various randomized-controlled clinical trials (RCTs) have investigated the neuroprotective role of minocycline in acute ischemic stroke (AIS) or acute intracerebral hemorrhage (ICH) patients. We sought to consolidate and investigate the efficacy and safety of minocycline in patients with acute stroke. Methods: Literature search spanned through November 30, 2017 across major databases to identify all RCTs that reported following effi

APA, Harvard, Vancouver, ISO, and other styles

33

Sudlow, Christopher Mark. "The prevalence of atrial fibrillation in the UK and of suitability for warfarin treatment amongst those with atrial fibrillation." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301176.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Campbell, Carla Hoffman. "Development and implementation of a protocol for treatment of in-patient ischemic stroke patients." Montana State University, 2011. http://etd.lib.montana.edu/etd/2011/campbell/CampbellC1211.pdf.

Full text

Abstract:

"Stroke continues to be a significant cause of mortality and morbidity in the United States. Approximately 700,000 Americans have a new or recurrent stroke each year, and stroke remains the third leading cause of death in the United States when considered independently from other cardiovascular diseases. Stroke also remains a leading cause of serious, long-term disability in the United States." (Schwamm, 2005, p.690) The purpose of this project was to develop an evidence based care management protocol for persons admitted to a small rural hospital with the symptoms or diagnosis of Is

APA, Harvard, Vancouver, ISO, and other styles

35

Willmot, Mark. "An investigation of GTN and NO related therapeutics in the treatment of acute stroke." Thesis, University of Nottingham, 2007. http://eprints.nottingham.ac.uk/10305/.

Full text

Abstract:

Background: High blood pressure is common in acute stroke and has been linked with poor outcome. Hence, outcome might be improved by lowering blood pressure. This thesis investigates the potential for glyceryl trinitrate, a nitric oxide donor, for lowering blood pressure in acute stroke. Methods: A systematic review was employed to clarify the relationship between outcome and BP in observational studies. Next two systematic reviews of animal studies using nitric oxide therapeutics in experimental stroke were performed to assess the effects on infarct volume and cerebral perfusion. Finally, two

APA, Harvard, Vancouver, ISO, and other styles

36

England, Timothy John. "Mobilisation of endogenous haematopoietic stem cells and their use as treatment for subacute stroke." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/13302/.

Full text

Abstract:

The potential application for stem cell therapy is vast. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke are underway. Colony stimulating factors (CSF) such as granulocyte colony stimulating factor (G-CSF), which have been used to mobilise haematopoietic stem cells (HSC), also show promise in treating stroke. Preclinical experiments evaluating the effect of G-CSF in stroke were meta-analysed; G-CSF significantly reduced lesion size in transient but not permanent models of ischaemic stroke. Further studies assessing dose-respon

APA, Harvard, Vancouver, ISO, and other styles

37

Kirkland, Scott, and University of Lethbridge Faculty of Arts and Science. "Modulation of recovery and compensation after stroke." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007, 2007. http://hdl.handle.net/10133/387.

Full text

Abstract:

Stress has been shown to exacerbate cell death and cognitive deficits after ischemic injury in rodents, however, little is known of the effects of stress on motor recovery. The objective of this present thesis is to examine the effects of chronic stress on skilled motor recovery after devascularization lesion in rats. It was found that pre-lesion stress induced the most behavioural impairments, while post-lesion stress exacerbated infarct volume. The effects of chronic multiple stress on skilled motor recovery after lesion was also examined. Chronic multiple stress did not modulate skilled mot

APA, Harvard, Vancouver, ISO, and other styles

38

Chan, Chu-fung, and 陳柱峰. "Neuroprotective effects of granulocyte-colony stimulating factor in a mice stroke model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B40687284.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Man, Lai-mei, and 文麗媚. "An exploratory study for the health seeking pattern of stroke survivors on alternative medicine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31978617.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Foroud, Afra, and University of Lethbridge Faculty of Arts and Science. "Moving from stroke to development : a deconstruction of skilled reaching in humans." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2008, 2008. http://hdl.handle.net/10133/1307.

Full text

Abstract:

The purpose of this thesis is to describe the organization of the movements of skilled reaching. Our knowledge of reaching behaviour has been limited to an understanding of specific actions. Results from this thesis describe how reaching is the product of interactions of various parameters that assemble in an integrative way in ontogeny, yet can become dismantled on one level, or generally, throughout multiple levels of what constitutes the behaviour after stroke in adults. These findings demonstrate that skilled reaching constitutes motor parameters that may not be visible in a healthy

APA, Harvard, Vancouver, ISO, and other styles

41

Hägg, Mary. "Sensorimotor Brain Plasticity in Stroke Patients with Dysphagia : A Methodological Study on Investigation and Treatment." Doctoral thesis, Uppsala University, Otolaryngology and Head and Neck Surgery, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8337.

Full text

Abstract:

<p><b>Aims</b></p><p>The aims of the thesis were to validate investigation instruments for stroke patients with dysphagia, and to improve oropharyngeal dysphagia therapies.</p><p><b>Methods/Results</b></p><p>A Lip Force Meter, LF 100, affirmed excellent intra- and inter-reliability, sensitivity and specificity. Controls had significantly stronger lip force (LF) and swallowing capacity (SC) than stroke patients. A normal lower limit of LF was set to 15 Newton. Dysphagia symptoms improved in 7 stroke patients after a 5-week sensorimotor stimulation therapy comprising manual body and facial regul

APA, Harvard, Vancouver, ISO, and other styles

42

Zou, Danni. "Fabrication and Characterization of Double-Walled Microsphere as a Drug Delivery System for Stroke Treatment." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42006.

Full text

Abstract:

Stroke is a medical condition in which poor blood flow to the brain results in cell death. The current treatment options are limited and only very few patients can benefit from these treatments. Stroke causes brain swelling and often a decompressive craniectomy is performed for some of the patients to release intracranial pressure to prevent further damage. As a result, a duraplasty is implanted to replace the surgically-damaged dura mater to protect the brain. In view of that, the purpose of this project was to develop double-walled microspheres (DWMS) which can be used as a drug delivery sys

APA, Harvard, Vancouver, ISO, and other styles

43

Kane, Ingrid. "Thrombolysis for acute ischaemic stroke : can brain imaging and consent processes before treatment be improved?" Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/24750.

Full text

Abstract:

The general aim of my research was to work on streamlining and improving a few key areas in the care for patients with stroke, particularly those likely to be candidates for thrombolysis. I focussed on: optimising the imaging method for patient selection; assessing the availability of different imaging methods; and evaluating a range of options for obtaining consent for treatment or research in this setting. In the imaging work I discuss some aspects of the two major imaging modalities available to stroke patients – computerised tomography (CT) and magnetic resonance imaging (MRI) and the evid

APA, Harvard, Vancouver, ISO, and other styles

44

Qi, Chuanjie, and 亓传洁. "Effects of notoginsenoside R1 against glutamate neurotoxicity in vitro and on mice brain following ischemic stroke in vivo." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206464.

Full text

Abstract:

Ischemic stroke is a leading cause of disability and death around the world. Higher concentration of glutamate following ischemic stroke is a factor leading to cell death, including neural stem cell death. Up to now no effective treatments of ischemic stroke are available. Notoginsenoside R1 (Noto R1) is the main component of Panax notoginseng, which is a traditional Chinese medicine for the treatment of cardiovascular disease. Its protective effects on the neural cell were noted recently. The main purpose of this experimental study was to investigate the mechanism of Noto R1 against glutamate

APA, Harvard, Vancouver, ISO, and other styles

45

Hadjisavvas, Venediktos. "Treatment of brain cancer and ischaemic stroke utilising High Intensity Focus Ultrasound (HIFU) guide with MRI." Thesis, City University London, 2012. http://openaccess.city.ac.uk/1399/.

Full text

Abstract:

In this thesis high intensity focused ultrasound (HIFU) is utilized for cancer treatment (thermal mode) and treatment of ischaemic stroke (mechanical mode). These two applications were investigated in vitro and in vivo models. MRI was utilized to monitor the lesions created by HIFU either in thermal or cavitation mode in freshly excised lamb brain tissue in vitro, and in rabbit brain in vivo. Additionally, MRI was used to monitor lesions deep in tissue for both in vitro and in vivo exposures. All three MRI sequences used (T1-W FSE, T2-W FSE and FLAIR) were able to detect lesions. Both thermal

APA, Harvard, Vancouver, ISO, and other styles

46

Gibson, Josephine Mary Evelyn. "Reducing uncertainty : an exploratory study of people's treatment decisions after transient ischaemic attack or minor stroke." Thesis, University of Central Lancashire, 2007. http://clok.uclan.ac.uk/6560/.

Full text

Abstract:

Little is known about people's responses to the impact of a transient ischaemic attack or minor stroke on their health status and future risk of stroke. In this thesis my aims are: to explore how the experience of TIA or minor stroke affects people's perception of their health and their uptake of health maintenance measures; to examine people's assessment, interpretation and perceptions of evidence in relation to their stroke risk; to explore the ways in which people reach decisions about treatment options in the light of their personal experience and in the context of evidence-based healthcar

APA, Harvard, Vancouver, ISO, and other styles

47

Balch, Maria Helen Harley. "Effects of Delayed Pharmacological Treatment and Limb Rehabilitation on Infarct Size and Functional Recovery After Stroke." Wright State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=wright1408630500.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Khanasari, Parto S. "An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental model of ischemic stroke." Scholarly Commons, 2007. https://scholarlycommons.pacific.edu/uop_etds/671.

Full text

Abstract:

Stroke is a devastating neurological disease with limited treatment opportunities. Recent advances in understanding the underlying pathogenesis of cerebral ischemia support the involvement of multiple biochemical pathways in the development of the ischemic injury. The work reported in this thesis was undertaken to investigate the hypothesis that fenamate NSAIDs have neuroprotective properties against ischemic stroke and to explore the underlying mechanisms for any efficacy. Fenamates are non-selective inhibitors of cyclooxygenases. In addition, fenamates are antagonists of non-selective cation

APA, Harvard, Vancouver, ISO, and other styles

49

Luo, Dan, and 骆丹. "Anti-inflammatory mechanisms of compound C from gastrodia and uncaria decoction, a commonly used post-stroke decoction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/211556.

Full text

Abstract:

Ischemic stroke is a leading cause of death and long-term disability in the world. Although many pathological aspects of mechanisms are considered to be involved in the stroke, accumulating evidences implicated that inflammation accounts for its progression and complications. Tumor necrosis factor-alpha (TNF-α) and nitric oxide are considered as key mediators produced by cells like microglia in the pathogenesis of the disease. Therefore, the development of therapies targeting at the suppression of nitric oxide and TNF-α productions may ameliorate the severity of ischemic stroke. Gastrodia and

APA, Harvard, Vancouver, ISO, and other styles

50

Gu, Yong, and 顧勇. "Targeting caveolin-1 as a therapeutic approach to prevent blood-brain barrier breakdown in ischemic stroke : from mechanism to isoflavones treatment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/197561.

Full text

Abstract:

Our group previously reported that caveolin-1 (cav-1) was down-regulated by nitric oxide (NO) during cerebral ischemia and reperfusion (I/R). However, the role of cav-1 in regulating blood-brain barrier (BBB) permeability is unclear yet. This study aims to address whether the loss of cav-1 induced by NO production affects BBB permeability. Data showed that the expression of cav-1 in isolated cortical microvessels was down-regulated in ischemia-reperfused rat brains subjected to middle cerebral artery occlusion (MCAO). Treatment of NG-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synth

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!