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Dissertations / Theses on the topic 'Structural and functional zones'

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Published: 4 June 2025
Last updated: 20 July 2025

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1

Noel, Joseph L. "Identification of taxonomic and functional ichthyofaunal zones within the James River Basin, Virginia." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5550.

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Environmental gradients structure ichthyofaunal communities longitudinally along river networks via the selective filtering of species’ traits. In many instances, these environmental influences have created distinct zones of co-occurring fish species. Zonation studies have most often been conducted with taxonomic data (species x site matrices), but the increasing availability of functional trait data creates an opportunity to build more rigorous understanding of species’ co-occurrence patterns. Notably, zonation studies that use taxonomic data may not reveal the same patterns as studies based
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2

NOZAKI, Kenji, and 謙二 野崎. "Japan’s Economic Structural Reform: Regulatory Reform and Special Zones for Structural Reform." 名古屋大学大学院経済学研究科附属国際経済政策研究センター, 2008. http://hdl.handle.net/2237/10878.

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3

Ibell, Timothy. "Behaviour of anchorage zones for prestressed concrete." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259477.

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4

Lipke, Katrin, Frank Krüger, and Dirk Rößler. "Subduction zone structure along Sumatra from receiver functions." Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2008/1826/.

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Receiver functions are a good tool to investigate the seismotectonic structure beneath the a seismic station. In this study we apply the method to stations situated on or near Sumatra to find constraints on a more detailed velocity model which should improve earthquake localisation. We estimate shallow Moho-depths (~ 21 km) close to the trench and depths of ~30 km at greater distances. First evidences for the dip direction of the slab of ~60° are provided. Receiver functions were calculated for 20 stations for altogether 110 earthquakes in the distance range between 30° and 95° from the recei
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5

Clark, Henry S. X. "Protein structure / function prediction within the twilight zone." Thesis, University of Essex, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412342.

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6

Gountouna, Viktoria-Eleni. "Multicentre structural and functional MRI." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9536.

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Neuroimaging techniques are likely to continue to improve our understanding of the brain in health and disease, but studies tend to be small, based in one imaging centre and of uncertain generalisability. Multicentre imaging studies therefore have great appeal but it is not yet clear under which circumstances data from different scanners can be combined. The successful harmonisation of multiple Magnetic Resonance Imaging (MRI) machines will increase study power, flexibility and generalisability. I have conducted a detailed study of the performance of three research MRI scanners in Scotland und
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7

Nagra, Manbir K. "Myopia : structural and functional correlates." Thesis, Aston University, 2010. http://publications.aston.ac.uk/10048/.

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Ocular dimensions are widely recognised as key variants of refractive error. Previously, accurate depiction of eye shape in vivo was largely restricted by limitations in the imaging techniques available. This thesis describes unique applications of the recently introduced 3-dimensional magnetic resonance imaging (MRI) approach to evaluate human eye shape in a group of young adult subjects (n=76) with a range of ametropia (MSE= -19.76 to +4.38D). Specific MRI derived parameters of ocular shape are then correlated with measures of visual function. Key findings include the significant homogeneity
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8

Karlsson, Anders. "Structural and functional properties of transthyretin." Doctoral thesis, Umeå universitet, Umeå centrum för molekylär patogenes (UCMP) (Teknisk-naturvetenskaplig fakultet), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1507.

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The hereditary transthyretin (TTR) amyloidoses are rare, and in severe cases, fatal disorders caused by mutations in the TTR gene. The clinical picture is diverse, involving neuropathies and myopathies, and mainly depends on the causative mutation and the sites and rates of amyloid deposition. The ultimate aim of the field of research presented in this thesis is to prevent TTR amyloid disease. To reach this ambitious goal, a thorough understanding of the normal as well as the pathological properties of the protein is essential. Here, comparisons between TTR from humans and other species may pr
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9

Smith-Forrester, Jenna Rae. "Structural and functional imaging of tauopathies." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54109.

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Repetitive head trauma is a known cause of tau protein accumulation and the leading cause of chronic traumatic encephalopathy (CTE). Currently, no robust method for in vivo detection of CTE exists and definitive diagnosis can only be made post-mortem. This thesis aimed to address two gaps in the literature surrounding head injury and tau accumulation. First, we sought to evaluate the effects of concussion on adolescent brain structure using mathematical modeling applied to diffusion tensor imaging (DTI). In our study, 12 adolescent athletes completed DTI in the sub-acute phase of recovery from
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10

Zhu, Ling. "Structural and functional study of picornaviruses." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:b589c6fd-daab-427b-b246-1ebec5431bf9.

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Picornaviruses are responsible for a variety of human and animal diseases, ranging from hepatitis A, foot and mouth disease, through polio to hand-foot-and-mouth disease and the common cold. In addition to their importance in causing diseases, they also serve as models for understanding the basic mechanisms of host-pathogen interactions, virus entry and viral genome release. Although the structure of a number of picornaviruses from the Entero, Cardio, Aphtho and Senecavirus genera have been determined at close to atomic resolution with X-ray crystallography, structural and functional studies o
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11

Vinson, Mary. "Structural and functional studies on sialoadhesin." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362115.

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12

Hansen, Soren Prag. "Structural and functional analysis of muskelin." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408222.

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13

Kerai, Preeti. "Structural and functional characterisation of PKCI." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325029.

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14

Wharton, J. T. "Structural functional surface design and manufacture." Thesis, Liverpool John Moores University, 2018. http://researchonline.ljmu.ac.uk/7782/.

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The main purpose of this investigation was to explore the potential benefits of structural functional surfaces using facilities available within the University. The potential benefits were demonstrated by applying functional surfaces to a set of particular engineering applications. The thesis mainly concentrated on improving the frictional performance of a surface structure for hydrodynamic bearing application. This thesis has also included some preliminary investigation into drag-reducing riblet structures but this chapter mainly discusses the development of a novel experimental apparatus whi
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15

Filippetto-Manon, Florence. "Structural and functional studies of NOD1." Université Joseph Fourier (Grenoble), 2006. http://www.theses.fr/2006GRE10101.

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NOD1 est une protéine de surveillance intracellulaire jouant un rôle crucial dans la défense immunitaire innée. Suite à la reconnaissance d'un ligand bactérien spécifique, NOD1 recrute RICK au moyen d'une interaction CARO-CARO. RICK module ensuite l'activation du facteur de transcription NF-KB et initie une cascade de signalisation pro-inflammatoire. Le but de cette thèse était de déterminer la base structurale de ce processus. Le domaine CARO de NOD1 a été cloné, exprimé et purifié à la station EMBL de Grenoble. La structure de ce domaine a été résolue par résonance magnétique nucléaire à l'I
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16

Zaleska, Mariola Krystyna. "Structural and functional characterisation of MS1." Thesis, King's College London (University of London), 2014. http://kclpure.kcl.ac.uk/portal/en/theses/structural-and-functional-characterisation-of-ms1(bfa94533-48b0-4c9c-ac53-5fec68e4977d).html.

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MS1 (Myocyte stress 1) is a muscle specific protein, implicated in the development of cardiac muscle hypertrophy. In rat models of induced left ventricular hypertrophy, MS1 expression is increased 3 times after applying stress signal with a peak expression before day 1. It may suggest that MS1 can act as a very important stress sensor that correlates external signals with a cellular response, however its complete mode of action needs to be further elucidated. It is has been proposed that MS1 is indirectly involved in gene expression regulation through a mechanism that involves actin dynamics a
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17

Pandya, Ashka Y. "Structural and functional analysis of KLF4." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2009r/pandya.pdf.

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18

Holland, Arthur Ekasatrya. "Structural and functional analysis of TREX." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/8312/.

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The TREX (Transcription-Export) complex is a well-conserved assembly of proteins, which is essential in eukaryotic gene expression. The expression of mRNA involves a number of processing events of primary transcripts to form a mature mRNA. TREX functions at the interface between transcription and export, associating with transcripts at various stages during its processing and packages it into an export-competent mRNP. Export of most mRNAs is dependent on the export receptor, Nxf1. This protein is recruited to the mRNP by directly binding to TREX components. Because the association of TREX with
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19

Ignea, Sorin. "Major Fracture Zones inFiskarfjärden, Stockholm." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-256355.

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This Master thesis is written in connection with the Stockholm Bypass project which is Trafikverkets and Sweden’s largest infrastructure project to date. It will consist of 21 km of motorway running west of Stockholm city linking the southern and the northern parts. Out of the total 21 km of motorway, 17 km will run through rock tunnels and cross beneath the Lake Mälaren at 3 places. One of these places is the water passage Fiskarfjärden, situated between Sätra and the island of Kunghatt which has been carefully studied with geological (drill core mapping, BIPS, Water-loss measurements and out
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20

Hernandez, Moreno Catalina <1981&gt. "Understanding block rotation of strike-slip fault zones: Paleomagnetic and structural approach." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6829/1/Tesi_Catalina_Hdz_M_1.pdf.

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This thesis is focused on the paleomagnetic rotation pattern inside the deforming zone of strike-slip faults, and the kinematics and geodynamics describing it. The paleomagnetic investigation carried out along both the LOFZ and the fore-arc sliver (38º-42ºS, southern Chile) revealed an asymmetric rotation pattern. East of the LOFZ and adjacent to it, rotations are up to 170° clockwise (CW) and fade out ~10 km east of fault. West of the LOFZ at 42ºS (Chiloé Island) and around 39°S (Villarrica domain) systematic CCW rotations have been observed, while at 40°-41°S (Ranco-Osorno domain) and adja
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21

Hernandez, Moreno Catalina <1981&gt. "Understanding block rotation of strike-slip fault zones: Paleomagnetic and structural approach." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6829/.

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This thesis is focused on the paleomagnetic rotation pattern inside the deforming zone of strike-slip faults, and the kinematics and geodynamics describing it. The paleomagnetic investigation carried out along both the LOFZ and the fore-arc sliver (38º-42ºS, southern Chile) revealed an asymmetric rotation pattern. East of the LOFZ and adjacent to it, rotations are up to 170° clockwise (CW) and fade out ~10 km east of fault. West of the LOFZ at 42ºS (Chiloé Island) and around 39°S (Villarrica domain) systematic CCW rotations have been observed, while at 40°-41°S (Ranco-Osorno domain) and adja
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22

Chorover, Jon, Louis A. Derry, and William H. McDowell. "Concentration-Discharge Relations in the Critical Zone: Implications for Resolving Critical Zone Structure, Function, and Evolution." AMER GEOPHYSICAL UNION, 2017. http://hdl.handle.net/10150/626479.

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Critical zone science seeks to develop mechanistic theories that describe critical zone structure, function, and long-term evolution. One postulate is that hydrogeochemical controls on critical zone evolution can be inferred from solute discharges measured down-gradient of reactive flow paths. These flow paths have variable lengths, interfacial compositions, and residence times, and their mixing is reflected in concentration-discharge (C-Q) relations. Motivation for this special section originates from a U.S. Critical Zone Observatories workshop that was held at the University of New Hampshire
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23

Wang, Junjie. "Functional and Structural Study of Pannexin1 Channels." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/207.

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Pannexins are vertebrate proteins with limited sequence homology to the invertebrate gap junction proteins, the innexins. However, in contrast to innexins and the vertebrate connexins, pannexins do not form gap junction channels. Instead they appear to solely function as unpaired membrane channels allowing the flux of molecules, including ATP, across the plasma membrane. We provided additional evidence for their ATP release function by demonstrating that the connexin mimetic peptides, which were thought to inhibit ATP release through connexin channels, do not inhibit their host connexin channe
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24

Celebi, Hatice. "Structural And Functional Analysis Of Henry James." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/597/index.pdf.

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The aim this thesis is to analyse the narrative structure of the novel, The Portrait of A Lady, with the aim of revealing how meaning is made and to show how certain elements are transferred to the film version and the consequent changes in meaning and emphasis. The structural analysis of The Portrait will chiefly rely on Shlomith Rimmon- Kenan&rsquo<br>s scheme she draws in her book Narrative Fiction. The functional analysis to show the consequent changes in meaning and emphasis, on the other hand, will rely on Roland Barthes&rsquo<br>s theory of functions he discusses in his article &ldquo<b
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25

Ribas, i. de Pouplana Lluís. "Structural and functional studies on Drosophila ADH." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/26877.

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The enzyme alcohol dehydrogenase of the fruit-fly <i>Drosophila</i> (DADH) catalyzes the same reaction as mammalian alcohol dehydrogenases, transforming alcohols into aldehydes through the reduction of nicotinamide-adenine-dinucleotide. Despite this apparently identical catalytic behaviour the enzyme has a strikingly different three-dimensional architecture to the mammalian alcohol dehydrogenases. The study of the structure-function relationships of DADH is of interest because large amounts of biochemical, evolutionary and genetical data have accumulated which require structural information on
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26

Runke, Gregory S. "Functional and structural studies of mitochondrial porin." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0012/MQ53217.pdf.

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27

Kozlenkov, Alexey. "Structural/functional studies on human alkaline phosphatases /." Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136.

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28

Robson, Catherine Ruth. "Aspects of ocular structural and functional assessment." Thesis, Cardiff University, 2006. http://orca.cf.ac.uk/55449/.

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This thesis is a continuation of previous work within the Research Group and comprises an investigation of two perimetry-related topics; firstly, the role of ocular media properties on the visual field derived by Short Wavelength Automated Perimetry (SWAP); and, secondly, the perimetric assessment of patients with epilepsy treated with vigabatrin and the potential of alternative (imaging) techniques to overcome the subjective limitations of perimetry. The influence of ocular media adsorption and intra-ocular straylight on the visual field indices Mean Sensitivity, Mean Deviation, Pattern Stand
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29

Taylor, Alexander Iain. "Structural and functional characterisation of avian IgY." Thesis, King's College London (University of London), 2007. https://kclpure.kcl.ac.uk/portal/en/theses/structural-and-functional-characterisation-of-avian-igy(243a793c-be0b-47bf-a48a-cfae4edea9e4).html.

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30

Gill, D. J. "Structural and functional organisation of ESCRT complexes." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599420.

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My structure of the highly conserved heterotrimeric ESCRT-I core provides a blueprint for the assembly of ESCRT-I. The structure shows a fan-like arrangement of three helical hairpins, each corresponding to a different subunit. Vps23/TSG101 is the central hairpin sandwiched between the other subunits, explaining the critical role of its “steadiness box” in the stability of ESCRT-I. Subsequently, Mvb12, a fourth subunit of ESCRT-I was identified in yeast. I find that Mvb12 engages ESCRT-I directly, with nanomolar affinity to form a 1:1:1:1 heterotetramer. Mvb12 plays a critical role in maintain
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31

Swain, Gemma V. "Structural and Functional Studies of Clostridial Phospholipases." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503819.

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32

Ioannidou, Sofia. "Structural and functional analysis of vascular permeability." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444750/.

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Vascular permeability and its regulation are indispensable for normal circulatory function and tissue homeostasis. When unregulated, vascular permeability contributes significantly to blood vessel related pathologies, such as cancer and diabetic retinopathy. Interposed between blood and tissues, endothelial cells become structurally and functionally differentiated, to mediate controlled permeability. The aim of this thesis work was to develop suitable systems to study two different aspects of vascular permeability, endothelial fenestrae formation and tyrosine phophatase-based regulation of par
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33

Lim, Eun Jeong. "STRUCTURAL AND FUNCTIONAL STUDIES OF SYNAPTIC ENZYMES." UKnowledge, 2006. http://uknowledge.uky.edu/gradschool_diss/259.

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Thimet oligopeptidase (TOP, EC 3.4.24.15) and neurolysin (EC 3.4.24.16) are zincdependent metallopeptidases that metabolize small bioactive peptides. The two enzymes share60 % sequence identity and their crystal structures demonstrate that they adopt nearly identicalfolds. They generally cleave at the same sites, but they recognize different positions on somepeptides, including neurotensin, a 13-residue peptide involved in modulation of dopaminergiccircuits, pain perception, and thermoregulation.On the basis of crystal structures and previous mapping studies, four residues(E469/R470, M490/R491
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34

Wu, QiongLi. "Sensitivity Analysis for Functional Structural Plant Modelling." Phd thesis, Ecole Centrale Paris, 2012. http://tel.archives-ouvertes.fr/tel-00719935.

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Global sensitivity analysis has a key role to play in the design and parameterization of functional-structural plant growth models (FSPM) which combine the description of plant structural development (organogenesis and geometry) and functional growth (biomass accumulation and allocation). Models of this type generally describe many interacting processes, count a large number of parameters, and their computational cost can be important. The general objective of this thesis is to develop a proper methodology for the sensitivity analysis of functional structural plant models and to investigate ho
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35

Moffett, C. L. "Structural and functional characterization of nematode neuropeptides." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390877.

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36

Pell, Gavin. "Structural and functional analysis of Cellvibrio hemicellulases." Thesis, University of Newcastle Upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413943.

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37

Snowden, B. W. "Structural and functional studies of herpesvirus glycoproteins." Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355709.

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Payne, Karl Alex Peter. "Structural and functional studies of aminopeptidase P." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435785.

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39

Cash, Diana. "Structural and functional imaging of experimental Parkinsonism." Thesis, King's College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407816.

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40

Thorne, Mark Richard. "Bovine inositol monophosphatase : structural and functional studies." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242491.

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41

Baker, Matthew Douglas. "Structural and functional studies on microbial superantigens." Thesis, University of Bath, 2001. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760765.

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42

Smith, Leanna Louise. "Structural and functional studies on CHFR autoubiquitination." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/41816.

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The antephase checkpoint plays an important role in delaying eukaryotic cell division in the presence of numerous stress conditions. Checkpoint with Fork-Head Associated (FHA) and RING domain (CHFR) is an E3 ubiquitin ligase and an integral component of the antephase checkpoint. Responsible for delaying mitotic entry in the presence of adverse conditions, downregulation of CHFR is frequently observed in numerous cancer cell lines and tumours. Previous studies have demonstrated N-terminal FHA-domain and C-terminal cysteine rich domain deficient CHFR proteins (CRD; ΔFHA-ΔCRD-CHFR) can form polyu
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43

Drulyte, Ieva. "Structural and functional studies of polyketide synthases." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22568/.

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Polyketides, natural products produced by multi-domain polyketide synthases (PKSs), have proven to be excellent starting points for drug discovery. Rational engineering of PKSs holds much promise for the generation of novel polyketide pharmaceuticals, however to enable this we need to gain a better understanding of how the mature polyketides are generated and how individual modules within a polyketide synthase assemble and interact. Here, work was performed to investigate three polypeptides from natural product indanomycin and rhizoxin biosynthesis, including the candidate polyketide cyclase I
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Ahmed, Mohammad Tabish. "Functional and structural characterisation of Mycobacterial Chaperonins." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1279/.

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In Mycobacterium tuberculosis there are 2 distinct groEL homologues which encode the chaperonins Cpn60.1 and Cpn60.2, with the latter predicted to be the main house-keeping chaperonin. Phylogenetic analysis has revealed that the genes for the duplicated chaperonins diverged a long time ago. This implies that the duplicated chaperonins have evolved for different cellular functions. Interestingly, while most chaperonins occur as stable large complexes with a characteristic double ring structure of 14 subunits, the Mycobacterial chaperonins are very unstable and appear to form much smaller comple
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45

Li, Ling Ph D. Massachusetts Institute of Technology. "Biomineralized structural materials with functional optical properties." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/89955.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 129-143).<br>Many biological structural materials exhibit "mechanical property amplification" through their intricate hierarchical composite designs. In the past several decades, significant progress has been achieved in elucidating the structure/mechanical property relationships of these materials. However, the design strategies of structural biomaterials with additional functional roles are still l
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Baytshtok, Vladimir. "Functional and structural studies of AAA+ proteases." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106729.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>AAA+ proteases are found in all domains of life. They degrade misfolded proteins as well as specific regulatory factors and thus play critical roles in protein quality control and numerous cellular processes. These enzymes share a conserved architecture in which a hexameric AAA+ ATPase recognizes, unfolds, and translocates substrates into an associated self-compartmentalized peptidase for degradation. In addition to participatin
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Feng, Xudong. "Structural and functional models for methane monooxygenase." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/28003.

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48

Hempel, Anne. "Structural and functional analysis of telomerase recruitment." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608273.

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49

Watson, Peter James. "Structural and functional studies on adaptor complexes." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615311.

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50

Lawthom, Charlotte. "Structural and functional investigations of vigabatrin toxicity." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/54806/.

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The purpose of this thesis was to investigate visual dysfunction arising from vigabatrin (VGB) toxicity: structural investigation utilising optical coherence tomography (OCT) and functional investigation using multifocal electrophysiology. OCT of the retinal nerve fibre layer (RNFL) based upon a fixed diameter circle scan and enabling reference to the manufacturers' large proprietary normative database, revealed a specific finding associated with vigabatrin-attributed visual field loss (VAVFL) namely, a characteristic pattern of nasal quadrant attenuation with a normal temporal quadrant thickn
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