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Journal articles on the topic 'Structural properties of thymol'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Ghavi, Fateme Poorsharbaf, Petr Golis, Martin Kubů, Jan Přech, and Maksym Opanasenko. "Acidity and porosity properties of zeolites affect their catalytic performance in thymol synthesis." Microporous and Mesoporous Materials 376 (May 27, 2024): 113198. https://doi.org/10.1016/j.micromeso.2024.113198.

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Thymol is synthesized from m-cresol alkylation reaction with 2-propanol. A few commercial zeolites have been tested in this reaction, but the influence of acidity and porosity of a zeolite on the m-cresol conversion and thymol yield is scarcely studied. Isomorphously-substituted Al-, Ga-, Fe-, B-, and In-UTL with different heteroelements and thus different ratio between strong and weak sites give insight into the effect of acidity. Isoreticular zeolites Al-UTL, Al-IPC-7, and Al-IPC-2 with different pore sizes reveal the effect of porosity. In this study, m-cresol conversion was far from compar

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2

Ghavi, Fateme Poorsharbaf, Petr Golis, Martin Kubů, Jan Přech, and Maksym Opanasenko. "Acidity and porosity properties of zeolites affect their catalytic performance in thymol synthesis." Microporous and Mesoporous Materials 376 (May 27, 2024): 113198. https://doi.org/10.5281/zenodo.13880572.

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Thymol is synthesized from m-cresol alkylation reaction with 2-propanol. A few commercial zeolites have been tested in this reaction, but the influence of acidity and porosity of a zeolite on the m-cresol conversion and thymol yield is scarcely studied. Isomorphously-substituted Al-, Ga-, Fe-, B-, and In-UTL with different heteroelements and thus different ratio between strong and weak sites give insight into the effect of acidity. Isoreticular zeolites Al-UTL, Al-IPC-7, and Al-IPC-2 with different pore sizes reveal the effect of porosity. In this study, m-cresol conversion was far from compar

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3

Lucic Skoric, Marija, Stoja Milovanovic, Irena Zizovic, et al. "Supercritical CO2 Impregnation of Thymol in Thermoplastic Starch-Based Blends: Chemico-Physical Properties and Release Kinetics." Polymers 14, no. 20 (2022): 4360. http://dx.doi.org/10.3390/polym14204360.

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The aim of the present study was to investigate starch-based materials, prepared in an environmentally friendly way and from renewable resources, suitable for the development of biodegradable active food packaging. For this purpose, a bioactive compound (thymol) was incorporated into thermoplastic starch (TPS) and a TPS blend with poly (ε-caprolactone) (TPS–PCL) by the supercritical CO2 (scCO2) impregnation process. Impregnation experiments with scCO2 were carried out at a pressure of 30 MPa and temperatures in the range of 40–100 °C during 1 to 20 h. The structural, morphological, and thermal

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4

Macku, Jan, Katerina Kubova, Martina Urbanova, et al. "Rational Design of Self-Emulsifying Pellet Formulation of Thymol: Technology Development Guided by Molecular-Level Structure Characterization and Ex Vivo Testing." Pharmaceutics 14, no. 8 (2022): 1545. http://dx.doi.org/10.3390/pharmaceutics14081545.

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The growing need for processing natural lipophilic and often volatile substances such as thymol, a promising candidate for topical treatment of intestinal mucosa, led us to the utilization of solid-state nuclear magnetic resonance (ss-NMR) spectroscopy for the rational design of enteric pellets with a thymol self-emulsifying system (SES). The SES (triacylglycerol, Labrasol®, and propylene glycol) provided a stable o/w emulsion with particle size between 1 and 7 µm. The ex vivo experiment confirmed the SES mucosal permeation and thymol delivery to enterocytes. Pellets W90 (MCC, Neusilin®US2, ch

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Shajia Haider, Yawar Ali Abidi, Affan Ahmad, Fareeda Islam, Aeliya Batool, and Syed Saqib Raza. "Enhanced Fluoride Release from Glass Ionomer Cements and Compomers Modified with Clove Oil and Thymol: A Step Toward Advanced Caries Prevention." Indus Journal of Bioscience Research 3, no. 1 (2025): 112–19. https://doi.org/10.70749/ijbr.v3i1.285.

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Dental caries, a prevalent global health issue, significantly impacts oral health and quality of life. Glass ionomer cements (GICs) and compomers, valued for their fluoride-releasing properties, are pivotal in caries prevention and management. This study explores the enhancement of fluoride release from GICs and compomers modified with natural additives—clove oil and thymol—at varying concentrations (0.5%, 1%, 2%). These additives, known for their bioactive and antimicrobial properties, were incorporated into the dental materials, and fluoride release was measured over 30 days. Disc-shaped spe

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6

Li, Xiuxiu, Xi Yang, Hong Deng, Yurong Guo, and Jia Xue. "Gelatin films incorporated with thymol nanoemulsions: Physical properties and antimicrobial activities." International Journal of Biological Macromolecules 150 (May 2020): 161–68. http://dx.doi.org/10.1016/j.ijbiomac.2020.02.066.

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7

Zhang, Huaiyong, Yongshuai Wang, Yilu Wang, et al. "Combination of Cinnamaldehyde with Carvacrol or Thymol Improves the Mechanical Properties of Tibia in Post-Peak Laying Hens." Animals 12, no. 22 (2022): 3108. http://dx.doi.org/10.3390/ani12223108.

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Roles of plant-derived cinnamaldehyde, carvacrol, and thymol in the gut and bone health of laying hens was evaluated in the present study. After acclimation for 2 weeks, a total 384 of 52-week-old laying hens were allocated into three groups for 6 weeks: (1) basal diet group (Ctrl), (2) combination of cinnamaldehyde with carvacrol group (CAR+CIN), and (3) blend of cinnamaldehyde with thymol (THY+CIN). The dietary essential oil level was 100 mg/kg. Each treatment group had eight replicate pens (16 birds/pen). The stiffness and ultimate load of the tibiae from both the CAR+CIN and THY+CIN groups

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8

Liu, Yuhao, Xutao Li, Jie Sheng, et al. "Preparation and Enhanced Antimicrobial Activity of Thymol Immobilized on Different Silica Nanoparticles with Application in Apple Juice." Coatings 12, no. 5 (2022): 671. http://dx.doi.org/10.3390/coatings12050671.

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In order to diminish the application limitations of essential oils (EOs) as natural antimicrobial components in the food industry, novel antimicrobial materials were designed and prepared by immobilization of thymol derivatives on silica particles with different morphologies (hollow mesoporous silica nanoparticles, MCM-41, amorphous silica). The structural characteristics of antimicrobial materials were estimated by FESEM, FT-IR, TGA, N2 adsorption-desorption, and small-angle XRD, and the results revealed that both mesoporous silica nanoparticles maintained the orderly structures and had good

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Kirkova, Desislava, Yordan Stremski, Maria Bachvarova, et al. "New Benzothiazole–Monoterpenoid Hybrids as Multifunctional Molecules with Potential Applications in Cosmetics." Molecules 30, no. 3 (2025): 636. https://doi.org/10.3390/molecules30030636.

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The Thymus vulgaris and Origanum vulgare essential oils (contained thymol and carvacrol in a range of 35–80%) are used in various products in the fields of medicine, cosmetics, and foods. Molecular hybridization between benzothiazole (BT) and phenolic monoterpenoids is a promising method for the development of biologically active compounds. New benzothiazole–monoterpenoid hybrids were synthesized through a regioselective α-amidoalkylation reaction of thymol and carvacrol with high yields (70–96%). This approach is both simple and cost-effective, employing easily accessible and inexpensive reag

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10

Bakytzhanova, M. S., K. H. Makhmudova, A. U. Tuyakbayeva, N. A. Utarbayeva, A. A. Bitkeyeva, and T. Atici. "Phytochemical and elemental composition of the Linaria cretacea Fisch ex Spreng (Plantaginaceae)." BULLETIN OF THE L.N. GUMILYOV EURASIAN NATIONAL UNIVERSITY. BIOSCIENCE SERIES 151, no. 2 (2025): 169–83. https://doi.org/10.32523/2616-7034-2025-151-2-169-183.

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The article presents the results of a phytochemical study of a rare species of the Republic of Kazakhstan Linaria cretacea Fisch ex Spreng. Specific biologically active compounds contained in the inflorescences, roots, and leaves of plants have demonstrated their pharmacological properties and biological activity, confirming that various phytochemical groups and individual compounds have beneficial effects. Of the total number of organic compounds detected in ethanol extracts, falcarinol (with a relative content of 16,51%) and thymol (with a relative content of 0,57%) in L. cretacea were ident

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11

Liu, Mengying, Ruheng Shen, Liyuan Wang, et al. "Preparation, Optimization, and Characterization of Bovine Bone Gelatin/Sodium Carboxymethyl Cellulose Nanoemulsion Containing Thymol." Foods 13, no. 10 (2024): 1506. http://dx.doi.org/10.3390/foods13101506.

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The aim of this study is to produce a biodegradable food packaging material that reduces environmental pollution and protects food safety. The effects of total solids content, substrate ratio, polyphenol content, and magnetic stirring time on bovine bone gelatin/sodium carboxymethylcellulose nanoemulsion (BBG/SCMC–NE) were investigated using particle size, PDI, turbidity, rheological properties, and zeta potential as evaluation indexes. The micro, structural, antioxidant, encapsulation, and release properties were characterized after deriving its optimal preparation process. The results showed

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12

Sharopov, Farukh S., Michael Wink, and William N. Setzer. "Radical Scavenging and Antioxidant Activities of Essential Oil Components – An Experimental and Computational Investigation." Natural Product Communications 10, no. 1 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000135.

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The antioxidant activities of eighteen different essential oil components have been determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay, the 2,2 ’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical cation assay, and the ferric reducing antioxidant power (FRAP) assay. The phenolic compounds, carvacrol, thymol, and eugenol, showed the best antioxidant activities, while camphor, menthol, and menthone were the least active. The structural and electronic properties of the essential oil components were assessed using density functional theory (DFT) at the

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13

Othman, Siti Hajar, Norhazirah Nordin, Nur Ayuni Aziera Azman, Intan Syafinaz Mohamed Amin Tawakkal, and Roseliza Kadir Basha. "Effects of nanocellulose fiber and thymol on mechanical, thermal, and barrier properties of corn starch films." International Journal of Biological Macromolecules 183 (July 2021): 1352–61. http://dx.doi.org/10.1016/j.ijbiomac.2021.05.082.

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14

Gouda, Mostafa, Long Sheng, Rana Muhammad Aadil, et al. "Interaction of Bioactive Mono-Terpenes with Egg Yolk on Ice Cream Physicochemical Properties." Foods 10, no. 8 (2021): 1686. http://dx.doi.org/10.3390/foods10081686.

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Using natural multi-function phytochemicals could be one of the best solutions for clean-label production. In this study, dairy ice creams were prepared containing 14% egg yolk and 0.1% of thymol (THY), trans-cinnamaldehyde (TC), menthol (MEN), or vanillin (VAN). Then, the physical, chemical, and structural characteristics were evaluated. Magnetic resonance imaging (MRI) analysis (a rapid, chemical-free, and non-invasive tool) was carried out to evaluate the water distribution. A multivariate analysis was conducted among all studied variables. According to the results, the overrun of the MEN i

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15

Szostek, Tomasz, Daniel Szulczyk, Jolanta Szymańska-Majchrzak, et al. "Design and Synthesis of Menthol and Thymol Derived Ciprofloxacin: Influence of Structural Modifications on the Antibacterial Activity and Anticancer Properties." International Journal of Molecular Sciences 23, no. 12 (2022): 6600. http://dx.doi.org/10.3390/ijms23126600.

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Sixteen new Ciprofloxacin derivatives were designed and successfully synthesized. In an in silico experiment, lipophilicity was established for obtained compounds. All compounds were screened for antimicrobial activity using standard and clinical strains. As for Gram-positive hospital microorganisms, all tested derivatives were active. Measured MICs were in the range 1–16 µg/mL, confirming high antimicrobial potency. Derivative 12 demonstrated activity against all standard Gram-positive Staphylococci, within the range of 0.8–1.6 µg/mL and was confirmed as the leading structure with MICs 1 µg/m

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16

Wanmolee, Wanwitoo, Wasawat Kraithong, Jakkapop Phanthasri, et al. "Structural properties and sustained antimicrobial activity of thymol-loaded cellulose nanofibers from one-pot synthesis via in situ dynamic microfluidization." International Journal of Biological Macromolecules 306 (May 2025): 141712. https://doi.org/10.1016/j.ijbiomac.2025.141712.

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17

Mollaamin, Fatemeh. "Characterizing the structural and physicochemical properties of medicinal plants as a proposal for treating of viral malady." Trends in Immunotherapy 7, no. 2 (2023): 2329. http://dx.doi.org/10.24294/ti.v7.i2.2329.

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Regarding coronavirus disease (COVID-19) pandemic, this research article wants to study some herbals as the probable therapy for this disease. Cinnamon leaves, curcuma longa (turmeric), ginger, mentha pulegium (pennyroyal), rosemary, salvia divinorum and thyme including some principal chemical compounds of cynnamil, curcumin, gingerol, pulegone, rosmarinic acid, salvinorina A and thymol, respectively, as a probable anti COVID-19 receptor have been selected. The possible roles of these medicinal plants in COVID-19 treatment have been carried out through quantum sensing methods. Formation of hyd

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18

Pickering, Jerry W., and Michael Wolcott. "Some Structural Properties of Thymus Leukemia Antigen (TL) Solubilized with Detergent1." Tissue Antigens 14, no. 3 (2008): 261–69. http://dx.doi.org/10.1111/j.1399-0039.1979.tb00848.x.

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19

Vaiwala, Rakesh, Pradyumn Sharma, and K. Ganapathy Ayappa. "Differentiating interactions of antimicrobials with Gram-negative and Gram-positive bacterial cell walls using molecular dynamics simulations." Biointerphases 17, no. 6 (2022): 061008. http://dx.doi.org/10.1116/6.0002087.

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Developing molecular models to capture the complex physicochemical architecture of the bacterial cell wall and to study the interaction with antibacterial molecules is an important aspect of assessing and developing novel antimicrobial molecules. We carried out molecular dynamics simulations using an atomistic model of peptidoglycan to represent the architecture for Gram-positive S. aureus. The model is developed to capture various structural features of the Staphylococcal cell wall, such as the peptide orientation, area per disaccharide, glycan length distribution, cross-linking, and pore siz

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20

Andrade-Ochoa, Sergio, Daniela Sánchez-Aldana, Luz María Rodríguez-Valdez, and Guadalupe Virginia Nevárez-Moorillón. "Evaluación in vitro y QSAR (Quantitative and Structure-Activity Relationship) de la actividad antifúngica de terpenoides obtenidos de aceites esenciales frente a Alternaria alternata y Fusarium oxysporum." Biomédica 43, Sp. 1 (2023): 156–69. http://dx.doi.org/10.7705/biomedica.6883.

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Introduction. Fungal genera Alternaria and Fusarium include human and plant pathogenic species. Several antifungals have been used for their control, but excessive use has contributed to resistance development in pathogens. An alternative to searching for and developing new antifungal agents is using essential oils and their main components, which have biological activities of interest in medicine and food production.Objective. To evaluate in vitro and in silico the antifungal activities of terpenoids against Alternaria alternata and Fusarium oxysporum.Materials and methods. The minimum inhibi

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Milevskii, Nikita A., Inna V. Zinov’eva, Arina V. Kozhevnikova, Yulia A. Zakhodyaeva, and Andrey A. Voshkin. "Sm/Co Magnetic Materials: A Recycling Strategy Using Modifiable Hydrophobic Deep Eutectic Solvents Based on Trioctylphosphine Oxide." International Journal of Molecular Sciences 24, no. 18 (2023): 14032. http://dx.doi.org/10.3390/ijms241814032.

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Hydrophobic deep eutectic solvents (HDES) are widely used as extractants. Usually, when preparing HDES, only the extraction ability of one component is taken into account, with the second serving as an “inert” component, whose effect on the extraction process is not taken into account. The present study demonstrates the possibility of controlling the selectivity of a hydrophobic deep eutectic solvent based on trioctylphosphine oxide (TOPO) by varying the substance that acts as a hydrogen bond donor, but which does not have an extractive ability. In the course of the work, the influence of the

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Valverde Sancho, Juan, Cristina Carreño Amate, María del Mar Caparrós Pérez, Omar Santana Méridas, and Luis F. Julio. "Biological Activity of Hybrid Molecules Based on Major Constituents of Cinnammomun verum and Thymus vulgaris Essential Oils." Life 13, no. 2 (2023): 499. http://dx.doi.org/10.3390/life13020499.

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Plants have been used by humans since ancient times due their antimicrobial and medicinal properties. Essential oils (EOs) are complex mixtures of secondary plant metabolites, including terpenoids, phenylpropanoids, and other aromatic compounds. Cinnamomun verum and Thyme vulgaris EOs and their organic extracts exert numerous biological activities because of their major compounds, particularly thymol, carvacrol, eugenol, and benzoic and cinnamic acid. The structural motifs presented by these phytochemicals are responsible for their biological activities. Modification or hybridization of these

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Gökoğlu, Elmas, Fulya Kıpçak, Tugba Taskin-Tok, Halil Duyar, and Zeynel Seferoğlu. "Structural analysis and calf thymus DNA/HSA binding properties of new carbazole derivative containing piperazine." Journal of Photochemistry and Photobiology A: Chemistry 426 (April 2022): 113720. http://dx.doi.org/10.1016/j.jphotochem.2021.113720.

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24

Tomičić, Zorica, Ružica Tomičić, Sunčica Kocić-Tanackov, and Peter Raspor. "Essential oils as antimicrobial and anti-adhesion agents against bacteria Salmonella Typhimurium and Staphylococcus aureus, and yeasts Candida albicans and Saccharomyces cerevisiae." Food and Feed Research, no. 00 (2022): 17. http://dx.doi.org/10.5937/ffr0-37683.

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A serious global problem with the increasing resistance of microorganisms to currently used antimicrobials has opened up the promotional research in the identification of new, more effective drugs with a broad spectrum of antimicrobial activities. Plant essential oils, due to the large biological and structural diversity of their components, are known to have many potential benefits. This study aimed to evaluate the antimicrobial and anti-adhesion activity of fifteen essential oils and their compounds against two bacterial and two yeast species responsible for food spoilage and infectious dise

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Tomičić, Zorica, Ružica Tomičić, Sunčica Kocić-Tanackov, and Peter Raspor. "Essential oils as antimicrobial and anti-adhesion agents against bacteria Salmonella Typhimurium and Staphylococcus aureus, and yeasts Candida albicans and Saccharomyces cerevisiae." Food and Feed Research 49, no. 2 (2022): 107–15. http://dx.doi.org/10.5937/ffr49-37683.

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A serious global problem with the increasing resistance of microorganisms to currently used antimicrobials has opened up the promotional research in the identification of new, more effective drugs with a broad spectrum of antimicrobial activities. Plant essential oils, due to the large biological and structural diversity of their components, are known to have many potential benefits. This study aimed to evaluate the antimicrobial and anti-adhesion activity of fifteen essential oils and their compounds against two bacterial and two yeast species responsible for food spoilage and infectious dise

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26

Piroš, Milan, Martin Schoeller, Katarína Koňariková, et al. "Structural and Biological Properties of Heteroligand Copper Complexes with Diethylnicotinamide and Various Fenamates: Preparation, Structure, Spectral Properties and Hirshfeld Surface Analysis." Inorganics 11, no. 3 (2023): 108. http://dx.doi.org/10.3390/inorganics11030108.

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Herein, we discuss the synthesis, structural and spectroscopic characterization, and biological activity of five heteroligand copper(II) complexes with diethylnicotinamide and various fenamates, as follows: flufenamate (fluf), niflumate (nifl), tolfenamate (tolf), clonixinate (clon), mefenamate (mef) and N, N-diethylnicotinamide (dena). The complexes of composition: [Cu(fluf)2(dena)2(H2O)2] (1), [Cu(nifl)2(dena)2] (2), [Cu(tolf)2(dena)2(H2O)2] (3), [Cu(clon)2(dena)2] (4) and [Cu(mef)2(dena)2(H2O)2] (5), were synthesized, structurally (single-crystal X-ray diffraction) and spectroscopically cha

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Çolak, Hakan, and Ercan Karaköse. "Structural, electrical and optical properties of green synthesized ZnO nanoparticles using aqueous extract of thyme (Thymus vulgaris)." Journal of Materials Science: Materials in Electronics 28, no. 16 (2017): 12184–90. http://dx.doi.org/10.1007/s10854-017-7033-0.

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Wang, C. R., G. H. Chen, and W. J. Mandy. "Identification of a rabbit class I-like thymocyte-specific antigen." Journal of Immunology 138, no. 10 (1987): 3352–59. http://dx.doi.org/10.4049/jimmunol.138.10.3352.

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Abstract The availability of a monoclonal antibody, 5E2, has made it possible to characterize a new class I-like thymocyte-specific antigen in the rabbit. Flow cytometry and cyto-fluorescent microscopy show that approximately 70 to 80% of the cells reacting with 5E2 are located throughout the thymic cortex. Structural studies reveal that the cell surface molecule recognized by 5E2 is a non-covalently associated heterodimer consisting of a 45,000 dalton glycoprotein and a low m.w. beta-2-microglobulin protein. Certain properties of the 5E2 antigen were similar to the murine TL and human T6 anti

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Dimitrijević, Milan Ž., Marko Z. Mladenović, Milica D. Nešić, Milan S. Dekić, Vidak N. Raičević, and Niko S. Radulović. "New Oxygenated Methoxy-p-Cymene Derivatives from Leopard’s Bane (Doronicum columnae Ten., Asteraceae) Essential Oil: Synthesis Facilitating the Identification of Isomeric Minor Constituents in Complex Matrices." Molecules 30, no. 2 (2025): 302. https://doi.org/10.3390/molecules30020302.

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Species of the genus Doronicum are known for their pharmacological properties and essential oils, the chemical composition of which remains inadequately studied. In this work, GC-MS analysis, synthesis, and spectral techniques (UV, IR, MS, and NMR) were employed to identify 83 constituents in the essential oil from D. columnae roots, which accounted for 98.1% of the total GC-peak area. The major components were thymyl isobutyrate (32.8%) and thymyl 2-methylbutyrate (22.8%), while the minor constituents were methoxy-p-cymene derivatives. Six new natural products were identified through synthesi

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Çakmakçi, Emrah, Ozan Deveoglu, Ahmed Muhammed, Ali Fouad, Emine Torgan, and Recep Karadag. "HPLC-DAD analysis of Thymus serpyllum based natural pigments and investigation of their antimicrobial properties." Pigment & Resin Technology 43, no. 1 (2013): 19–25. http://dx.doi.org/10.1108/prt-07-2012-0045.

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Purpose – In this study, it was aimed to investigate the antibacterial properties of natural pigments prepared from Thymus serpyllum. Design/methodology/approach – Al (III), Fe (II), Sn (II) and Cu (II) complexed natural pigments were obtained by using a precipitation method and the main constituents in the pigments were identified with HPLC-DAD. Also FTIR analysis was performed for further structural characterization. Moreover, the thermal stability and thermal degradation properties of the pigments were analyzed by thermogravimetric analyses (TGA). The antimicrobial activity of the thyme pla

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Mason, David L., Marietta L. Harrison, and Robert L. Geahlen. "Properties of a tyrosine protein kinase from calf thymus. Response to ionic strength and divalent cations." Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 829, no. 2 (1985): 221–28. http://dx.doi.org/10.1016/0167-4838(85)90191-8.

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Zhu, Zhu, Tiantian Min, Xueji Zhang, and Yongqiang Wen. "Microencapsulation of Thymol in Poly(lactide-co-glycolide) (PLGA): Physical and Antibacterial Properties." Materials 12, no. 7 (2019): 1133. http://dx.doi.org/10.3390/ma12071133.

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Thymol has been shown to be a safe and effective broad-spectrum antimicrobial agent that can be used as a food preservative. However, its volatile characteristics and strong odor limit its use in food products. The microencapsulation of this essential oil in biopolymers could overcome these disadvantages. In this work, thymol-loaded poly(lactide-co-glycolide) (PLGA) microparticles were successfully prepared and the optimal encapsulation efficiency was obtained at 20% (w/w) thymol. Microparticles containing thymol presented a spherical shape and smooth surface. Microencapsulation significantly

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Tanzadehpanah, Hamid, Hanie Mahaki, Pouria Samadi, et al. "Anticancer activity, calf thymus DNA and human serum albumin binding properties of Farnesiferol C from Ferula pseudalliacea." Journal of Biomolecular Structure and Dynamics 37, no. 11 (2018): 2789–800. http://dx.doi.org/10.1080/07391102.2018.1497543.

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Shan, Yingying, Shiqin Chen, Jingjing Zhang, et al. "Preparation of Citral Compound and Its Bamboo Antimildew Properties." Polymers 14, no. 21 (2022): 4691. http://dx.doi.org/10.3390/polym14214691.

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To reduce the amount of citral used without reducing the antimildew performance of bamboo, the citral compound preparation process, the distribution of the compound in bamboo, and its antimildew performance were investigated using the Oxford cup method, Fourier-transform infrared spectroscopy, and ultraviolet spectrophotometry. The results revealed that the combination of citral with cinnamaldehyde or thymol may lead to partial chemical reactions, which may change the chemical structure of citral and affect its bacteriostatic properties. The bacteriostatic properties of the citraldehyde thymol

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Simescu-Lazar, Florica, Soukaina Slaoui, Mohamed Essahli, et al. "Thymus satureoides Oil as Green Corrosion Inhibitor for 316L Stainless Steel in 3% NaCl: Experimental and Theoretical Studies." Lubricants 11, no. 2 (2023): 56. http://dx.doi.org/10.3390/lubricants11020056.

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The protection of 316L stainless steel in 3% NaCl by the essential oil of Thymus satureoides has been studied by many techniques such as potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), atomic force microscopy (AFM) and scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy analysis (EDXS). The results show that the corrosion rate of 316L stainless steel decreases with the increase in the concentration of the inhibitor up to an efficiency of 82% for a concentration of 1600 ppm. The Thymus satureoides oil acts as an anode inhibitor. The v

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Ramos, Marina, Elena Fortunati, Ana Beltrán, et al. "Controlled Release, Disintegration, Antioxidant, and Antimicrobial Properties of Poly (Lactic Acid)/Thymol/Nanoclay Composites." Polymers 12, no. 9 (2020): 1878. http://dx.doi.org/10.3390/polym12091878.

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Nano-biocomposite films based on poly (lactic acid) (PLA) were prepared by adding thymol (8 wt.%) and a commercial montmorillonite (D43B) at different concentrations (2.5 and 5 wt.%). The antioxidant, antimicrobial, and disintegration properties of all films were determined. A kinetic study was carried out to evaluate the thymol release from the polymer matrix into ethanol 10% (v/v) as food simulant. The nanostructured networks formed in binary and ternary systems were of interest in controlling the release of thymol into the food simulant. The results indicated that the diffusion of thymol th

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Leung, Clarus, Samuel J. Wadsworth, S. Jasemine Yang, and Delbert R. Dorscheid. "Structural and functional variations in human bronchial epithelial cells cultured in air-liquid interface using different growth media." American Journal of Physiology-Lung Cellular and Molecular Physiology 318, no. 5 (2020): L1063—L1073. http://dx.doi.org/10.1152/ajplung.00190.2019.

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The human bronchial epithelium is an important barrier tissue that is damaged or pathologically altered in various acute and chronic respiratory conditions. To represent the epithelial component of respiratory disease, it is essential to use a physiologically relevant model of this tissue. The human bronchial epithelium is a highly organized tissue consisting of a number of specialized cell types. Primary human bronchial epithelial cells (HBEC) can be differentiated into a mucociliated tissue in air-liquid interface (ALI) cultures using appropriately supplemented media under optimized growth c

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Othman, Siti Hajar, Bilguisse Mamadou Wane, Norhazirah Nordin, Noor Zafira Noor Hasnan, Rosnita A. Talib, and Joko Nugroho Wahyu Karyadi. "Physical, Mechanical, and Water Vapor Barrier Properties of Starch/Cellulose Nanofiber/Thymol Bionanocomposite Films." Polymers 13, no. 23 (2021): 4060. http://dx.doi.org/10.3390/polym13234060.

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The application of starch films, such as food packaging materials, has been restricted due to poor mechanical and barrier properties. However, the addition of a reinforcing agent, cellulose nanofibers (CNF) and also thymol, into the films, may improve the properties of films. This work investigates the effects of incorporating different concentrations of thymol (3, 5, 7, and 10 wt.%) on physical, mechanical, water vapor barrier, and antibacterial properties of corn starch films, containing 1.5 wt.% CNF produced using the solvent casting method. The addition of thymol does not significantly aff

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Nathany, Shrinidhi, Rupal Tripathi, and Anurag Mehta. "Gene of the month: GTF2I." Journal of Clinical Pathology 74, no. 1 (2020): 1–4. http://dx.doi.org/10.1136/jclinpath-2020-207013.

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The GTF2I is a general transcription factor and its mutations have been reported to be recurrent in thymic epithelial tumours and are rare in other malignancies. Apart from thymic epithelial tumours, these mutations have also been reported in a subgroup of T cell lymphomas, angioimmunoblastic T cell lymphomas. Soft tissue angiofibroma has been reported to harbour GTF2I-NCOA2 fusion, whereas GTF2I partners with Retinoic acid receptor alpha (RARA) in acute promyelocytic leukaemia as GTF2I-RARA. GTF2I has also been implicated in immune disorders and two neuropsychiatric genetic disorders, namely

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Bulyakova, N. V., and V. S. Azarova. "Structural properties of regenerating muscle and the state of thymus after laser therapy of injured muscle in different periods of regeneration." Biology Bulletin 33, no. 6 (2006): 542–52. http://dx.doi.org/10.1134/s1062359006060033.

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Blažíčková, Michaela, Jaroslav Blaško, Róbert Kubinec, and Katarína Kozics. "Newly Synthesized Thymol Derivative and Its Effect on Colorectal Cancer Cells." Molecules 27, no. 9 (2022): 2622. http://dx.doi.org/10.3390/molecules27092622.

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Thymol affects various types of tumor cell lines, including colorectal cancer cells. However, the hydrophobic properties of thymol prevent its wider use. Therefore, new derivatives (acetic acid thymol ester, thymol β-D-glucoside) have been synthesized with respect to hydrophilic properties. The cytotoxic effect of the new derivatives on the colorectal cancer cell lines HT-29 and HCT-116 was assessed via MTT assay. The genotoxic effect was determined by comet assay and micronucleus analysis. ROS production was evaluated using ROS-Glo™ H2O2 Assay. We confirmed that one of the thymol derivatives

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Starkova, Tatiana Y., Alexander M. Polyanichko, Tatiana O. Artamonova, Anna S. Tsimokha, Alexey N. Tomilin, and Elena V. Chikhirzhina. "Structural Characteristics of High-Mobility Group Proteins HMGB1 and HMGB2 and Their Interaction with DNA." International Journal of Molecular Sciences 24, no. 4 (2023): 3577. http://dx.doi.org/10.3390/ijms24043577.

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Non-histone nuclear proteins HMGB1 and HMGB2 (High Mobility Group) are involved in many biological processes, such as replication, transcription, and repair. The HMGB1 and HMGB2 proteins consist of a short N-terminal region, two DNA-binding domains, A and B, and a C-terminal sequence of glutamic and aspartic acids. In this work, the structural organization of calf thymus HMGB1 and HMGB2 proteins and their complexes with DNA were studied using UV circular dichroism (CD) spectroscopy. Post-translational modifications (PTM) of HMGB1 and HMGB2 proteins were determined with MALDI mass spectrometry.

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Aubais-aljelehawy, Qassim Hassan, Shadieh Mohammadi, Elham Mohamadian, Allah Osamah Raji Mal, Alireza Mirzaei, and Mobin Ghahremanlou. "Antimicrobial, anticancer, antidiabetic, antineurodegenerative, and antirheumatic." Micro Nano Bio Aspects 2, no. 1 (2023): 1–7. https://doi.org/10.22034/mnba.2023.381107.1019.

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Thymol is monoterpenic phenol with a wide range of therapeutic properties. Various pharmacological properties including antimicrobial, antineoplastic, anti-inflammatory, antidiabetic, antirheumatic, and antineurodegenerative have been found for this metabolite. The severity of peripheral nerve dysfunction in diabetes mellitus can be ameliorated by thymol treatment via decreasing tumor necrosis factor-α (TNF- α) and nitric oxide levels. In the case of the anticancer mechanism, thymol can increase the expression of the tumor suppressor of p53, Bcl-2-associated X protein (Bax), and ap

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Zahari, Nur Amirah Asifa Raisha, Gun Hean Chong, Luqman Chuah Abdullah, and Bee Lin Chua. "Ultrasonic-Assisted Extraction (UAE) Process on Thymol Concentration from Plectranthus Amboinicus Leaves: Kinetic Modeling and Optimization." Processes 8, no. 3 (2020): 322. http://dx.doi.org/10.3390/pr8030322.

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Thymol shows potential medical values and it can be extracted from plants and herbs. In this study, ultrasonic-assisted extraction (UAE) was used to extract thymol from Plectranthus amboinicus leaves. From the extraction kinetics analysis of UAE on thymol, it was found that the highest concentration was collected at temperature of 25 °C with 5.51% of thymol concentration yield. An equilibrium-dependent solid–liquid extraction (EDSLE) model was found to be the best fitted model for thymol extraction using UAE. The parameters for optimization were the temperature of extraction (40 to 60 °C), ext

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PANTIC, IGOR, SENKA PANTIC, JOVANA PAUNOVIC, and MILAN PEROVIC. "Nuclear entropy, angular second moment, variance and texture correlation of thymus cortical and medullar lymphocytes: Grey level co-occurrence matrix analysis." Anais da Academia Brasileira de Ciências 85, no. 3 (2013): 1063–72. http://dx.doi.org/10.1590/s0001-37652013005000045.

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Grey level co-occurrence matrix analysis (GLCM) is a well-known mathematical method for quantification of cell and tissue textural properties, such as homogeneity, complexity and level of disorder. Recently, it was demonstrated that this method is capable of evaluating fine structural changes in nuclear structure that otherwise are undetectable during standard microscopy analysis. In this article, we present the results indicating that entropy, angular second moment, variance, and texture correlation of lymphocyte nuclear structure determined by GLCM method are different in thymus cortex when

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Dinu, Maria Valentina, Adina Catinca Gradinaru, Maria Marinela Lazar, et al. "Physically cross-linked chitosan/dextrin cryogels entrapping Thymus vulgaris essential oil with enhanced mechanical, antioxidant and antifungal properties." International Journal of Biological Macromolecules 184 (August 2021): 898–908. http://dx.doi.org/10.1016/j.ijbiomac.2021.06.068.

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Gorvel, J. P., I. Vivier, P. Naquet, P. Brekelmans, A. Rigal, and M. Pierres. "Characterization of the neutral aminopeptidase activity associated to the mouse thymocyte-activating molecule." Journal of Immunology 144, no. 8 (1990): 2899–907. http://dx.doi.org/10.4049/jimmunol.144.8.2899.

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Abstract We previously characterized a dimeric, Mr = 115,000, developmentally regulated mouse T cell-activating molecule (THAM). We show in this report that the THAM-specific mAb H194-112 exhibits strong reactivity with several nonlymphoid tissues including polarized enterocytes from small intestine, kidney cortical tubuli, and liver bile ductuli, as well as kidney glomeruli and lung alveoloar pneumocytes. Both the tissue distribution and the structural features of THAM made it likely that this molecule belongs to the ectoenzyme family. This was confirmed by the following experimental evidence

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Wu, Yan, Ming Wei Yuan, Ji Yi Yang, Yu Yue Qin, Ming Long Yuan, and Jian Xin Cao. "Physical Properties and Antimicrobial Activity of a Poly(Lactic Acid)/Poly(Trimethylene Carbonate) Film Incorporated with Thymol." Advanced Materials Research 884-885 (January 2014): 481–84. http://dx.doi.org/10.4028/www.scientific.net/amr.884-885.481.

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Thymol (TH), which has antimicrobial effect on many food pathogens, was incorporated as antimicrobial agent into composite poly (lactic acid)/poly (trimethylene carbonate)(PLA-PTMC) films. Antimicrobial active films based on PLA-PTMC were prepared by incorporating thymol at five different concentrations: 0, 3, 6, 9 and 12 %(w/w). The mechanical characterization, water vapor permeability (WVP), and antimicrobial activity of all formulations composite film were carried out. A decrease in elastic modulus was obtained for the active composite film compared with neat PLA-PTMC film. The presence of

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B, Mittu. "Nanotechnology as a Tool to Improve the Biological Activity of Thymol: A Review." Bioequivalence & Bioavailability International Journal 7, no. 2 (2023): 1–13. http://dx.doi.org/10.23880/beba-16000220.

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Thymol is a naturally occurring compound found in the essential oils of thyme, oregano, and other plants. It has been shown to have a variety of pharmacological activities, including antimicrobial, antioxidant, and anti-inflammatory properties. In recent years, researchers have investigated the potential of thymol as an anticancer agent. However, thymol has limited solubility and poor bioavailability, which limits its use as a therapeutic agent. To overcome these limitations, researchers have developed various nano-based drug delivery systems (NDDS) to improve the efficacy of thymol. In this a

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Robledo, Sara, Edison Osorio, Diana Muñoz, et al. "In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives." Antimicrobial Agents and Chemotherapy 49, no. 4 (2005): 1652–55. http://dx.doi.org/10.1128/aac.49.4.1652-1655.2005.

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ABSTRACT The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs.

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