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Journal articles on the topic 'Structurally weak regions'

Author: Grafiati

Published: 7 June 2025

Last updated: 16 July 2025

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1

Genett, Timm, Peggy Richter, Madita Schädlich, Anke Schlieker, and Hannes Schlieter. "Gesundheitsnetze in strukturschwachen Regionen." Monitor Versorgungsforschung 2025, no. 02 (2025): 40–46. https://doi.org/10.24945/mvf.02.25.1866-0533.2706.

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Introduction: Demographic change poses major challenges for medical care in Germany. Structurally weak regions in particular are already suffering from gaps in care, which are being exacerbated by the increasing demand for healthcare services and the simultaneous shortage of specialised medical staff. Regional healthcare networks, which follow the integrated care approach, offer a promising solution by improving care and making it more efficient through greater cooperation between healthcare stakeholders. However, networking is often context- and region-specific, meaning that existing approach

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2

Hennebry, Barraí, and Tadeusz Stryjakiewicz. "Classification of Structurally Weak Rural Regions: Application of a Rural Development Index for Austria and Portugal." Quaestiones Geographicae 39, no. 2 (2020): 5–14. http://dx.doi.org/10.2478/quageo-2020-0014.

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AbstractThis paper aims to analyse to what extent the level and dynamics of development of rural regions located in two firmly different countries, Austria and Portugal, differ. In order to do this, an index to measure the ‘structural strength’ of rural regions was created. This index is a more holistic measure of socio-economic development than the traditional GDP per capita. After the identification of structurally weak regions in both Austria and Portugal, the paper compares them in the context of challenges faced by such regions.

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Harfst, Jörn, Patrick Pichler, and Wolfgang Fischer. "Regional Ambassadors – An Innovative Element for the Development of Rural Areas?" European Countryside 9, no. 2 (2017): 359–74. http://dx.doi.org/10.1515/euco-2017-0022.

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Abstract Rural regions in Austria have been under increasing pressure for change in the last decades. On a regional level, varying development patterns of shrinkage and growth arise alongside economic, demographic and social parameters. In this paper, regional ambassador concepts will be explicated as a new instrument of regional development. Additionally, potential positive impacts of these approaches on the problems faced by rural, structurally weak regions will be highlighted. Notable advantages of these approaches are network and feedback effects between stakeholders. These, in turn, are c

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Ganesch, Franziska. "Regional Mobility and Spatial Inequality: Determinants of Spatial Labor Market Behavior Considering Firm- and Region-Specific Factors." Raumforschung und Raumordnung 76, no. 6 (2018): 497–514. http://dx.doi.org/10.1007/s13147-018-0551-2.

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Abstract Regional disparities exist between states as well as within countries. In the Federal Republic of Germany, as a result of reunification, there are still considerable regional differences in terms of economic conditions. Local economic and structural circumstances affect individual employment opportunities and can be a motive for migration. Based on rational-economic approaches, the article examines the spatial labor market behavior of full-time employees subject to social security contributions, taking into account individual, firm-specific and regional characteristics. Workplace mobi

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Haas, Anette, Annekatrin Niebuhr, and Niklas Vetterer. "Regionale Arbeitsmärkte unter Transformationsdruck –unterschiedliche Herausforderungen und Anpassungspotenziale." Wirtschaftsdienst 104, no. 8 (2024): 527–32. http://dx.doi.org/10.2478/wd-2024-0139.

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Abstract The transformation pressure caused by digitalisation, decarbonisation and demographic change differs between regional labour markets, as does the potential to adapt to these changes. For structurally weak (rural) regions, high transformation pressure due to digitalisation and/or decarbonisation is often accompanied by significant demographic problems. Policies should aim to increase innovation and further training in lagging regions, as these are of strategic importance for addressing the challenges of transformation.

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Alm, Bastian, and Antje Weyh. "Fördergebiete neu abgrenzen: Für eine proaktivere Regionalpolitik." Wirtschaftsdienst 105, no. 6 (2025): 407–13. https://doi.org/10.2478/wd-2025-0106.

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Abstract This article examines the role of place-based policies in Germany aimed at strengthening structurally weak regions and ensuring equitable living conditions across the country, focusing on the future delineation of assisted areas. It highlights the need for robust, evidence-based approaches to address regional disparities amid structural change, demographic shifts and economic shocks. Using sectoral specialisation and crisis resilience indicators, the study argues for a nuanced and data-driven redesign of funding boundaries to better support heterogeneous regional potential and promote

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Stognief, Nora, Paula Walk, Oliver Schöttker, and Pao-Yu Oei. "Economic Resilience of German Lignite Regions in Transition." Sustainability 11, no. 21 (2019): 5991. http://dx.doi.org/10.3390/su11215991.

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This paper recalls the development of the German lignite regions Rhineland and Lusatia since 1945 to allow for a better understanding of their situation in 2019. We analyze their economic resilience, defined as adaptive capacity, using Holling’s adaptive cycle model. We find that the Rhineland is currently in the conservation phase, while Lusatia experiences a reorganization phase following the economic shock of the German reunification. Key policy recommendations for the upcoming coal phase-out are to foster innovation within the Rhineland’s infrastructures to avoid overconnection, and to exp

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8

Alecke, Björn, Timo Mitze, and Annekatrin Niebuhr. "Building a bridge over the valley of death? New pathways for innovation policy in structurally weak regions." Review of Regional Research 41, no. 2 (2021): 185–210. http://dx.doi.org/10.1007/s10037-021-00156-9.

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9

Lupu, Noam. "Weak parties and the inequality trap in Latin America." Oxford Open Economics 4, Supplement_1 (2025): i585—i594. https://doi.org/10.1093/ooec/odae020.

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Abstract Latin America is widely acknowledged as one of the most unequal regions of the world, yet it is also one of the most democratic. And in every country in the region, majorities support government redistribution. Why, then, are democratic governments not responding to voter demands to reduce inequality? I argue that one important reason is that strong political parties are necessary to achieve broad-based redistributive programs. Research on the political economy of inequality in the region and the institutionalization of political parties emphasizes this factor, spotlighting the weakne

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Ostrouch, Tymon. "Caught Between Metropolises: The Smart Specialisation Challenge in Poland’s Lubusz Region." Sustainability 17, no. 14 (2025): 6270. https://doi.org/10.3390/su17146270.

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This article examines the relevance of Smart Specialisation Strategies (RIS3) in structurally weak but non-peripheral regions, using Poland’s Lubusz Voivodeship as a case study. Based on employment data from 2009 and 2021, this study uses Location Quotient (LQ) analysis to evaluate the alignment between the region’s economic structure and its RIS3 domains: Innovative Industry, Health and Quality of Life, and Green Economy. The findings show that while Innovative Industry and Health and Quality of Life strengthened their relative specialisation, the Green Economy domain made only limited progre

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Lenk, Alexander, and Steffen Bohm. "Entlastung von Arztpraxen und zukunftsfähige Versorgung." Monitor Versorgungsforschung 2024, no. 06 (2024): 38–39. https://doi.org/10.24945/mvf.06.24.1866-0533.2667.

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More than 16 million people over the age of 67 live in Germany. This figure is expected to rise to over 20 million by 2040. As the proportion of older people in the population increases, so too will the number of chronically ill, multi-morbid and care-dependent people. The care problem will become particularly acute in rural and structurally weak regions, as the demographic developments described above tend to be more pronounced here than in urban areas. As a result of this development, the already tense situation in many doctors' surgeries will become even more acute. At the same time, there

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Shin, D. H., J. Silcox, S. E. Russek, D. K. Lathrop, B. H. Moeckly, and R. A. Buhrman. "Structure of high-angle-tilt boundaries in YBa2Cu3-O7-x thin films." Proceedings, annual meeting, Electron Microscopy Society of America 49 (August 1991): 1086–87. http://dx.doi.org/10.1017/s0424820100089743.

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It has been known that high angle tilt grain boundaries in c-axis oriented YBa2Cu3O7-x thin films cause weak link behavior in the transport properties reducing Jc's by several orders of magnitude. These grain boundaries have been shown to be clean both structurally and chemically by high resolution imaging and microanalysis studies. Therefore the mechanism of weak link behavior in thin film YBa2Cu3O7-x is not yet understood.Recently it has been deduced from the behavior of weak link Jc under small magnetic fields that the high angle tilt boundaries are nonuniform, consisting of several regions

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Ali, Mosaad, Shulin Sun, Wei Qian, Abdou Dodo Bohari, Dusabemariya Claire, and Yan Zhang. "Application of Resistivity Method for Mining Tailings Site Selection in Karst Regions." E3S Web of Conferences 144 (2020): 01002. http://dx.doi.org/10.1051/e3sconf/202014401002.

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Disposal of mining wastes (tailings) is one of the most severe issues related to groundwater contamination. Therefore, a properly selected disposal site helps to prevent the leakage of dissolved materials in the tailings to groundwater, especially in the karstic area. Where the karstic environment is one of the challenges facing groundwater environmental and engineering issues, for instance, groundwater exploration, vulnerability assessment, and hazard estimation. In this study, the resistivity method with a high-resolution surface data survey was carried out to investigate the pond location s

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Kontuly, T., and K. P. Schön. "Changing Western German Internal Migration Systems during the Second Half of the 1980s." Environment and Planning A: Economy and Space 26, no. 10 (1994): 1521–43. http://dx.doi.org/10.1068/a261521.

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The slow downward trend toward greater spatial deconcentration in West Germany during the time period 1970 to 1984 shifted back toward concentration from 1985 and through 1988. This ‘swing back’ occurred over only a three-year period. Regional labor-market changes appear to be the only factor able to cause such an abrupt shift to concentration, suggesting the importance of the regional restructuring hypothesis as an explanation. Changing internal migration patterns by two age-groups, 25–29 and 30–49, were responsible for the shift. A reduction of net in-migration to intermediate-sized regions

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15

Royer, Jeroen, and Tim Leibert. "Suspended in time? Peripheralised and “left behind” places in Germany." Geographica Helvetica 79, no. 3 (2024): 221–37. http://dx.doi.org/10.5194/gh-79-221-2024.

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Abstract. The term “left behind” has regained attention with the increasing signs of political dissatisfaction in the Global North, e.g. the rise of right-wing populist parties and politicians. In Germany, terms such as abgehängte Regionen (suspended regions) or “structurally weak” regions are often employed as alternatives. However, there is a certain fuzziness in these terminologies, as they often encompass different spatial scales and temporal dependencies and refer to a variety of regions, e.g. deindustrialising cities as well as peripheral and remote rural areas. Our approach conceptualis

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Vilanova, M., J. Vendrell, C. M. Cuchillo, and F. X. Avilés. "Analysis of the conformation and ligand-binding properties of the activation segment of pig procarboxypeptidase A." Biochemical Journal 251, no. 3 (1988): 901–5. http://dx.doi.org/10.1042/bj2510901.

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The isolated activation segment of pig procarboxypeptidase A binds two Tb3+ ions in a strong and specific way. In contrast, the binding of Ca2+, Cd2+ and Mg2+ is weak. The binding of Tb3+ increases the resistance of the isolated activation segment against proteolysis and competes for the binding of the carbocyanine dye Stains-All. This dye forms complexes with the activation segment showing spectral properties similar to those observed with EF-hand structures. The presented results support a previous hypothesis on the existence of two regions in the activation segment of pancreatic procarboxyp

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17

Saitluanga, Benjamin L. "Globalisation, Urbanisation and Spatial Inequality in India with special reference to North East India." Space and Culture, India 1, no. 2 (2013): 21. http://dx.doi.org/10.20896/saci.v1i2.27.

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Globalisation, an increasing international interaction in economic, political and cultural aspects, is a highly uneven set of processes whose impact varies over space, through time, and between social groups. On one hand, as globalisation seems to be an inevitable reality, many developing countries are restructuring their economies to receive and reap the benefits of widening and deepening global economic interactions. On the other hand, there are regions, which are increasingly excluded, and ‘structurally irrelevant’ to the current process of globalisation. Moreover, cities are at the core of

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18

Mariš, Martin, and Eleonóra Marišová. "Labor specialization and its impact on spatial patterns of unemployment." Gazdaság és Társadalom, no. 1-2 (2015): 41–57. http://dx.doi.org/10.21637/gt.2015.1-2.03.

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Nowadays, the unemployment is crucial problem and challenge for the competitiveness of each economics. In connection with the failure of a socialistic regime in Central and Eastern Europe countries (CEE countries) and establishment of the market economy, unemployment became a permanent component of their national economy. Currently, each CEE country is touching with the unemployment, which varies according the age, gender, ethnicity and also by the region. Most common features of this phenomena is that the employment or unemployment is spatially distributed very unevenly. Slovak republic is on

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Ermakova, Natalia A., and Lera A. Karimova. "Issues of Cluster Formation in East Germany." Administrative Consulting, no. 1 (169) (June 7, 2023): 63–77. https://doi.org/10.22394/1726-1139-2023-1-63-77.

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The article is devoted to modern innovation policy in Germany. The German government considers stimulation of cluster structures as a necessary condition for achieving high-tech development of the country, so the cluster policy is a component of German innovation policy. The article considers the concept of three-level organization of clusters, quantifies the value of regional asymmetry in investment in innovation. Based on the classification of clusters by M. Porter, using the methodology of the analysis of cluster sectors of the European Cluster Observatory, the author&rs

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20

Yan, Y., M. A. Kirk, and J. E. Evetts. "Structure of grain boundaries: Correlation to supercurrent transport in textured Bi2Sr2Can−1CunOx bulk material." Journal of Materials Research 12, no. 11 (1997): 3009–28. http://dx.doi.org/10.1557/jmr.1997.0395.

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Two kinds of characteristic grain boundaries were observed in textured Bi2Sr2Can−1CunOx (n = 2 and 3) bulk material: one (P-type) is nearly parallel to the (001) plane, and the other (N-type) is approximately normal to the (001) plane. Low-angle tilt N-type boundaries are composed of arrays of dislocations. However, for a small c-axis misorientation, the regions between the dislocation cores are still well connected, providing “pathways” for supercurrents crossing the boundary plane. The P-type boundaries exhibit compositionally and structurally modulated faceting. Although we see local region

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21

Kotov, Aleksandr. "Updated System Supporting Regional Development in Germany." Scientific and Analytical Herald of IE RAS 21, no. 3 (2021): 94–100. http://dx.doi.org/10.15211/vestnikieran3202194100.

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The long-term trajectory of the German regional policy is formed by the terms of overcoming the consequences of the coronavirus pandemic. The article discusses in this context the comprehensive all-German system for financing structurally weak regions, provides information on specific programs in 2020–2021, and also shows the connection with European instruments for financing regional policy in 2021–2027. The restructuring of this system of support measures was designed to improve the situation in underdeveloped territories and to help reduce differences in the conditions of recent challenges

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22

Leibert, Tim, Manuel Wolff, and Annegret Haase. "Shifting spatial patterns in German population trends: local-level hot and cold spots, 1990–2019." Geographica Helvetica 77, no. 3 (2022): 369–87. http://dx.doi.org/10.5194/gh-77-369-2022.

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Abstract. The population development of German municipalities is characterized by pronounced regional disparities. We seek to shed new light on the shifting patterns of population development in Germany at the local level between 1990 and 2019 to understand better the drivers of population development at the local level and to initiate a debate on the (dis)advantages of longitudinal analyses of population change at the local level and the resulting methodological challenges. We address three interrelated questions: (1) how do patterns of local population trends shift over time and in space? (2

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Smith, Angela R., Jesus A. Alonso, Cory M. Ayres, Nishant K. Singh, Lance M. Hellman, and Brian M. Baker. "Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner." Proceedings of the National Academy of Sciences 118, no. 4 (2021): e2018125118. http://dx.doi.org/10.1073/pnas.2018125118.

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Presentation of peptides by class I MHC proteins underlies T cell immune responses to pathogens and cancer. The association between peptide binding affinity and immunogenicity has led to the engineering of modified peptides with improved MHC binding, with the hope that these peptides would be useful for eliciting cross-reactive immune responses directed toward their weak binding, unmodified counterparts. Increasing evidence, however, indicates that T cell receptors (TCRs) can perceive such anchor-modified peptides differently than wild-type (WT) peptides, although the scope of discrimination i

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Mushaben, Joyce Marie. "The Dialectical Identity of Eastern Germans." German Politics and Society 37, no. 3 (2019): 55–71. http://dx.doi.org/10.3167/gps.2019.370305.

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Germans have now been unified for thirty years, longer than they had been separated by concrete barriers, yet the Wall in their respective heads has persisted. Unequal wages, a lack of investment in structurally weak regions, and ongoing western elite domination continue to fuel Eastern perceptions of second-class citizenship, despite significant shifts in the fates of key social groups who initially saw themselves as the “winners” and losers” of unification. This article considers the dialectical identities of four groups whose collective opportunity structures have been dramatically reconfig

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Trang Le, Thi Huyen, and Nina Kolleck. "The Power of Places in Building Cultural and Arts Education Networks and Cooperation in Rural Areas." Social Inclusion 10, no. 3 (2022): 284–94. http://dx.doi.org/10.17645/si.v10i3.5299.

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Volunteering plays a central role in cultural and arts education in rural areas in Germany. However, a decrease in the number of volunteers in structurally weak regions can be observed in recent years. This poses existential challenges for cultural and arts education. The promotion of social networks and regional cooperation, as well as a sense of place, can counteract this decline. This article aims to explore how sense of place influence cooperation and thus social networks between actors of different institutions in the context of cultural and arts education in rural areas. A total of 34 in

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Alaei-Mahabadi, Babak, Joydeep Bhadury, Joakim W. Karlsson, Jonas A. Nilsson, and Erik Larsson. "Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers." Proceedings of the National Academy of Sciences 113, no. 48 (2016): 13768–73. http://dx.doi.org/10.1073/pnas.1606220113.

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Tumor genomes are mosaics of somatic structural variants (SVs) that may contribute to the activation of oncogenes or inactivation of tumor suppressors, for example, by altering gene copy number amplitude. However, there are multiple other ways in which SVs can modulate transcription, but the general impact of such events on tumor transcriptional output has not been systematically determined. Here we use whole-genome sequencing data to map SVs across 600 tumors and 18 cancers, and investigate the relationship between SVs, copy number alterations (CNAs), and mRNA expression. We find that 34% of

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Behnke, Craig A., Isolde Le Trong, Jeff W. Godden, et al. "Atomic resolution studies of carbonic anhydrase II." Acta Crystallographica Section D Biological Crystallography 66, no. 5 (2010): 616–27. http://dx.doi.org/10.1107/s0907444910006554.

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Carbonic anhydrase has been well studied structurally and functionally owing to its importance in respiration. A large number of X-ray crystallographic structures of carbonic anhydrase and its inhibitor complexes have been determined, some at atomic resolution. Structure determination of a sulfonamide-containing inhibitor complex has been carried out and the structure was refined at 0.9 Å resolution with anisotropic atomic displacement parameters to anRvalue of 0.141. The structure is similar to those of other carbonic anhydrase complexes, with the inhibitor providing a fourth nonprotein ligan

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GARSOUX, Geneviève, Josette LAMOTTE, Charles GERDAY, and Georges FELLER. "Kinetic and structural optimization to catalysis at low temperatures in a psychrophilic cellulase from the Antarctic bacterium Pseudoalteromonas haloplanktis." Biochemical Journal 384, no. 2 (2004): 247–53. http://dx.doi.org/10.1042/bj20040325.

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The cold-adapted cellulase CelG has been purified from the culture supernatant of the Antarctic bacterium Pseudoalteromonas haloplanktis and the gene coding for this enzyme has been cloned, sequenced and expressed in Escherichia coli. This cellulase is composed of three structurally and functionally distinct regions: an N-terminal catalytic domain belonging to glycosidase family 5 and a C-terminal cellulose-binding domain belonging to carbohydrate-binding module family 5. The linker of 107 residues connecting both domains is one of the longest found in cellulases, and optimizes substrate acces

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Kim, Seonah, Hyunhee So, Ji Hye Lee, et al. "Photophysical Properties of Spirobifluorene-Based o-Carboranyl Compounds Altered by Structurally Rotating the Carborane Cages." Molecules 24, no. 22 (2019): 4135. http://dx.doi.org/10.3390/molecules24224135.

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9,9′-Spirobifluorene-based o-carboranyl compounds C1 and C2 were prepared and fully characterized by multinuclear nuclear magnetic resonance (NMR) spectroscopy and elemental analysis. The solid-state structure of C1 was also determined by single-crystal X-ray diffractometry. The two carboranyl compounds display major absorption bands that are assigned to π−π* transitions involving their spirobifluorene groups, as well as weak intramolecular charge-transfer (ICT) transitions between the o-carboranes and their spirobifluorene groups. While C1 only exhibited high-energy emissions (λem = ca. 350 n

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Swanson, Larry W., Joel D. Hahn, Lucas G. S. Jeub, Santo Fortunato, and Olaf Sporns. "Subsystem organization of axonal connections within and between the right and left cerebral cortex and cerebral nuclei (endbrain)." Proceedings of the National Academy of Sciences 115, no. 29 (2018): E6910—E6919. http://dx.doi.org/10.1073/pnas.1807255115.

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The endbrain (telencephalon) is at the rostral end of the central nervous system and is primarily responsible for supporting cognition and affect. Structurally, it consists of right and left cerebral hemispheres, each parceled into multiple cortical and nuclear gray matter regions. The global network organization of axonal macroconnections between the 244 regions forming the endbrain was analyzed with a multiresolution consensus clustering (MRCC) method that provides a hierarchical description of community clustering (modules or subsystems) within the network. Experimental evidence was collate

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Burkhardt, J. K., S. Hester, C. K. Lapham, and Y. Argon. "The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments." Journal of Cell Biology 111, no. 6 (1990): 2327–40. http://dx.doi.org/10.1083/jcb.111.6.2327.

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Cytolytic lymphocytes contain specialized lytic granules whose secretion during cell-mediated cytolysis results in target cell death. Using serial section EM of RNK-16, a natural killer cell line, we show that there are structurally distinct types of granules. Each type is composed of varying proportions of a dense core domain and a multivesicular cortical domain. The dense core domains contain secretory proteins thought to play a role in cytolysis, including cytolysin and chondroitin sulfate proteoglycan. In contrast, the multivesicular domains contain lysosomal proteins, including acid phosp

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Cosier, James, Eva Šabec, Luka Verlič, et al. "Understanding disparities in Slovenian rural areas: various new indicatiors." Geoadria 19, no. 2 (2017): 149. http://dx.doi.org/10.15291/geoadria.32.

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It has been widely accepted that regional development disparities are multi-faceted: on the one hand they hinder the development potentials of structurally weak rural areas, whilst on the other they stimulate faster development in distinctive, leading areas, thus re-creating old and generating new, more complex, regional differences. The paper focuses on quantitative ways of understanding the nature of rural disparities in Slovenia where the vast majority of national territory is defined as "rural" by OECD indicators. From the methodological perspective, single- and multi-level indicators were

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Halldorsson, Skarphedinn, Siri Fløgstad Svensson, Henriette Engen Berg, et al. "OTEH-7. Molecular characterization of tumor stiffness in glioblastoma." Neuro-Oncology Advances 3, Supplement_2 (2021): ii11—ii12. http://dx.doi.org/10.1093/noajnl/vdab070.046.

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Abstract Tumor heterogeneity is one of the hallmarks of glioblastoma multiforme (GBM). Morphology within a given GBM tumor can be extremely variable where some regions of the tumor have a soft, gel-like structure while other areas are dense and fibrous. Abnormal mechanical stress and tissue stiffening caused by cancer proliferation are believed to affect vascularity by compressing structurally weak blood vessels and restricting the supply of nutrients and oxygen to the tissue. These effects contribute to a hypoxic microenvironment that promotes disease progression and chemoresistance. The gene

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Burlingham, William J., Ewa Jankowska-Gan, Lynn DeVito-Haynes, et al. "HLA (A*0201) Mimicry by Anti-Idiotypic Monoclonal Antibodies." Journal of Immunology 161, no. 12 (1998): 6705–14. http://dx.doi.org/10.4049/jimmunol.161.12.6705.

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Abstract Soluble MHC Ags and anti-Id (anti-anti-MHC) Abs have both been shown to inhibit MHC alloantigen-specific B cell responses in vivo. We hypothesized that some anti-idiotypic Abs function as divalent molecular mimics of soluble HLA alloantigen. To test this idea, we studied two well-defined anti-idiotypic mAbs, T10-505 and T10-938, elicited in syngeneic BALB/c mice by immunization with CRll-351, an HLA-A2,24,28-specific mAb. Each anti-Id induced “Ab-3” Abs in rabbits that cross-reacted with HLA-A2 but not with HLA-B Ags. Furthermore, each anti-Id could bind to and block Ag recognition by

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Kiese, Matthias, and Julian Kahl. "Competitive funding in North Rhine-Westphalia." Competitiveness Review: An International Business Journal 27, no. 5 (2017): 495–515. http://dx.doi.org/10.1108/cr-09-2016-0062.

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Purpose This paper aims to examine a cluster-based strategy implemented in the German federal state of North Rhine-Westphalia under the 2007-2013 “Regional Competitiveness and Employment” programme. Departing from traditional discretionary approaches, a substantial share of the funds was now allocated on a competitive basis. The authors analyse the resulting distribution of funds across stakeholders and sub-regions and try to assess the pros and cons of this process, which constitutes a novel delivery system for cluster policies. Design/methodology/approach Following a literature review, the p

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Salomon, G. W., T. New, R. A. Muir, et al. "Geomorphological and geophysical analyses of the Hebron Fault, SW Namibia: implications for stable continental region seismic hazard." Geophysical Journal International 229, no. 1 (2021): 235–54. http://dx.doi.org/10.1093/gji/ggab466.

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SUMMARY This study explores the geomorphological expression and geological context of a normal fault scarp in a stable continental region (SCR) which we interpret as having failed in large (Mw &gt;7) earthquakes. Records of such large normal faulting events in an SCR (or even in more rapidly deforming regions) are extremely rare, and so understanding this feature is of international interest. The scarp is exceptionally well-preserved due to the extensive calcrete/silcrete cementation. In areas where this cementation is reduced or absent the scarp is more diffuse, as expected for a feature

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Kovacic, Peter, and Ratnasamy Somanathan. "Zolpidem, A Clinical Hypnotic that Affects Electronic Transfer, Alters Synaptic Activity Through Potential Gaba Receptors in the Nervous System Without Significant Free Radical Generation." Oxidative Medicine and Cellular Longevity 2, no. 1 (2009): 52–57. http://dx.doi.org/10.4161/oxim.2.1.7859.

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Zolpidem (trade name Ambien) has attracted much interest as a sleep-inducing agent and also in research. Attention has been centered mainly on receptor binding and electrochemistry in the central nervous system which are briefly addressed herein. A novel integrated approach to mode of action is presented. The pathways to be discussed involve basicity, reduction potential, electrostatics, cell signaling, GABA receptor binding, electron transfer (ET), pharmacodynamics, structure activity relationships (SAR) and side effects. The highly conjugated pyridinium salt formed by protonation of the amid

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Goldberg, Omri, Israel Greenfeld, and Hanoch Daniel Wagner. "Efficient Toughening of Short-Fiber Composites Using Weak Magnetic Fields." Materials 13, no. 10 (2020): 2415. http://dx.doi.org/10.3390/ma13102415.

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Short fibers may serve as toughening agents of composite materials because of the high energy dissipated during fracture, associated with numerous fiber pullouts. An ongoing challenge is to improve their toughness even further, by directing and concentrating fibers near highly stressed structural regions. Weak magnetic fields are utilized to increase the fracture toughness of an epoxy matrix reinforced by short magnetized glass fibers by directing and concentrating fibers near highly stressed structural regions. The orientation and local concentration of the fibers are controlled by the vector

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Pietak, Lukasz. "Structural Funds and Convergence in Poland." Revista Hacienda Pública Española 236, no. 1 (2021): 3–37. http://dx.doi.org/10.7866/hpe-rpe.21.1.1.

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This study aimed to investigate whether cohesion policy funds affected economic growth and resulted in a convergence process across NUTS 2 regions in Poland. The study examined a balanced panel of data from 16 Polish regions between 2004 and 2016 and applied different estimations procedures, in-cluding the fixed effects estimator –as the main estimator– and the GMM estimator. The empirical analysis revealed that cohesion policy funds had a positive impact on regional economic growth. How-ever, the influence of structural funds on convergence was shown to be weak in Poland. The results were rob

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Buchta, S. "Economic strength of Slovakia’s regions." Agricultural Economics (Zemědělská ekonomika) 50, No. 4 (2012): 139–44. http://dx.doi.org/10.17221/5181-agricecon.

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The article deals with the identification and categorisation of economic power of Slovak regions on the base of collecting of unemployment support payment from the employers, employees, and natural persons entrepreneurs into the employment fund. The analysis shows that during the last years, the number of rich regions has decreased and there rises the number of counties which have to be supported by the division of means from the rich counties. The article consequently categorises the development of economically strong and weak counties of Slovakia in the years 1999&ndash;2002 and marks th

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Pancha, Aasha, and John Taber. "Weak motion attenuation of peak ground acceleration in the North Island, New Zealand." Bulletin of the New Zealand Society for Earthquake Engineering 32, no. 3 (1999): 125–45. http://dx.doi.org/10.5459/bnzsee.32.3.125-145.

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Attenuation relations using weak ground motion recordings have been determined using data from the New Zealand National Seismograph Network and several temporary seismograph deployments. Models have been developed for earthquake sources in four regions: the Eastern North Island deep and shallow regions and the Central North Island (CNI) deep and shallow regions. Deep events were those with hypocenters below 33 km. Regression coefficients have been determined using the attenuation models of Joyner and Boore (1981) and Molas and Yamazaki (1995). The anelastic attenuation rates in the Easte

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Sunitha, Margaret S., Anu G. Nair, Amol Charya, Kamalakar Jadhav, Sami Mukhopadhyay, and Ramanathan Sowdhamini. "Structural attributes for the recognition of weak and anomalous regions in coiled-coils of myosins and other motor proteins." BMC Research Notes 5, no. 1 (2012): 530. http://dx.doi.org/10.1186/1756-0500-5-530.

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Khakimov, Gayrat Akramovich Abduraimova Khadicha Rakhmankulovna Muminov Abdujamil Abduxalilovich Berdimurodov Abdukihayum Sobirova Zulfiya. "CONSTRUCTION OF BUILDINGS AND STRUCTURES IN DIFFICULT SOIL CONDITIONS AND SEISMIC REGIONS OF THE REPUBLICS OF CENTRAL ASIA." INTERNATIONAL BULLETIN OF APPLIED SCIENCE AND TECHNOLOGY 3, no. 6 (2023): 315–19. https://doi.org/10.5281/zenodo.8019713.

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This scientific article describes modern methods of arranging artificial foundations for buildings and structures erected in difficult soil conditions and seismic areas, on subsidence loess and weak water-saturated clay soils. Also, information is given on some reliable structural measures (use of deep foundations, pile foundations, cutting structures with sedimentary seams, installation of strapping belts, etc.) used in buildings and structures in difficult soil conditions and seismic areas.

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Manuilova, E. A. "Neotectonics of the central part of the West-Siberian plate." Moscow University Bulletin. Series 4. Geology 1, no. 1 (2022): 23–30. http://dx.doi.org/10.33623/0579-9406-2021-1-23-30.

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Structural and geomorphological analysis of the territory of the West Siberian plate allowed us to establish its latest structural plan. Neotectonic regions (NO), regional and local newest structures, as well as weak zones and discontinuous faults are identified. Automated decoding and mapping using the method of V.P. Filosofov made it possible to clarify the boundaries of regional structures, identify the most extensive discontinuous violations, and compare the data obtained.

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Котелевская, Ю. В., and А. А. Степанов. "Problems of youth migration in the regions." Экономика и предпринимательство, no. 6(131) (August 9, 2021): 350–55. http://dx.doi.org/10.34925/eip.2021.131.6.067.

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В статье рассмотрены проблемы миграции молодежи в регионах, оказывающая негативное влияние на развитии рынка труда и в целом на социально-экономическое развитие регионов. Именно молодежь является носителем инновационных идей и двигателем нововведений в экономике. Рынку труда Севастополя присущи особенности, среди которых статус города федерального значения и военного геостратегического объекта, относительно новый этап институционализации экономики Севастополя, санкции и слабая коллаборация крупного бизнеса, неорганизованность занятости (сезонность), которые, несмотря на увеличение численности

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Guskov, A. E., A. A. Ermakov, A. V. Malysheva, and I. V. Selivanova. "Scientometrical analysis of research collaborations in Siberian Federal District regions." Scientific and Technical Libraries, no. 3 (March 24, 2025): 83–110. https://doi.org/10.33186/1027-3689-2025-3-83-110.

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The authors explore the structural changes in scientific collaborations in Siberian regions applying the method of scientometrical analysis of publications. After many years of growth, in 2022–2023 the scientific cooperation of Russian institutions with those in Europe and North America drastically reduced. The most significant changes took place in Novosibirsk and Tomsk regions that earlier had been leading in international collaborations. In the other Siberian regions the decline is less significant. Every discipline experiences the recession, moreover in many cases the scientific contacts w

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Syamaladevi, Divya P., James A. Spudich, and R. Sowdhamini. "Structural and Functional Insights on the Myosin Superfamily." Bioinformatics and Biology Insights 6 (January 2012): BBI.S8451. http://dx.doi.org/10.4137/bbi.s8451.

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The myosin superfamily is a versatile group of molecular motors involved in the transport of specific biomolecules, vesicles and organelles in eukaryotic cells. The processivity of myosins along an actin filament and transport of intracellular ‘cargo’ are achieved by generating physical force from chemical energy of ATP followed by appropriate conformational changes. The typical myosin has a head domain, which harbors an ATP binding site, an actin binding site, and a light-chain bound ‘lever arm’, followed often by a coiled coil domain and a cargo binding domain. Evolution of myosins started a

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Philippidis, George, and Ana Sanjuán-López. "A Re-Examination of the Structural Diversity of Biobased Activities and Regions across the EU." Sustainability 10, no. 11 (2018): 4325. http://dx.doi.org/10.3390/su10114325.

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This study evaluates the performance of European Union (EU) member state biobased activities. More specifically, statistical clustering techniques, based on biobased sectors’ demand and supply driven multipliers, identify regional EU typologies of biobased sector performance. The aim is to establish sector-region combinations of biobased driven economic growth. The study employs a consistent macroeconomic accounting dataset, known as a social accounting matrix (SAM). The dataset (dubbed BioSAM), is enriched with detailed accounts for agrifood activities, as well as further contemporary sources

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Kost, M. V., N. L. Bolsheva, N. S. Badaev, and A. V. Zelenin. "Regularities of in situ nick translation labeling pattern of cereal metaphase chromosomes." Genome 34, no. 1 (1991): 131–38. http://dx.doi.org/10.1139/g91-020.

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A method of nick translation in situ that makes it possible to detect regions hypersensitive to DNase I in metaphase chromosomes has been modified for plants. Such regions have a peculiar structural conformation typical of transcriptionally active chromatin. The distribution of transcriptionally active regions labeled with [3H]TTP along the length of individual chromosomes of rye and B genome of wheat was studied. The following regularities of this distribution were found: a weak labeling of heterochromatic regions; an increase in the intensity of labeling in regions located at the border of e

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Zimmermann, Daniel. "Cohesion Policy as a Driver to Promote Good Governance in the EU Member States." Central and Eastern European eDem and eGov Days 341 (March 17, 2022): 397–408. http://dx.doi.org/10.24989/ocg.v341.29.

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The quality of public institutions has a major impact on the social and economic development within the EU member states. Regions with high government effectiveness, low corruption and highquality public services tend to have higher outcomes in economic performance and social inclusion. In case of EU cohesion policy funding, the Seventh Cohesion Report published by the European Commission in 2017 demonstrates that regions with weak institutions have difficulties in absorbing regional development influences effectively and using the European structural funds properly in order to promote growth.

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