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1

Dodge, J. A. "Structure/activity relationships." Pure and Applied Chemistry 70, no. 9 (1998): 1725–33. http://dx.doi.org/10.1351/pac199870091725.

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2

Muhammad, Imran Qadir. "Recent Structure Activity Relationship Studies of 1,4-Benzodiazepines." Open Journal of Chemistry 1, no. 1 (2015): 008–12. https://doi.org/10.17352/ojc.000002.

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Structure activity relationship studies of 1,4-benzodiazepines have been discussed especially with their effects as antianxiety and anticonvulsants. The currently available benzodiazepines are associated with various side effects. Nowadays the purpose of these studies is to minimize side effects with these drugs. A very little alteration is possible on the benzene ring while the modification can be done on the diazepine ring. It can adopt the different conformations and in some cases some aromatic and heterocyclic rings have been fused with this part in order to see the effect of these conform
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3

Luke, B. T. "Fuzzy structure-activity relationships." SAR and QSAR in Environmental Research 14, no. 1 (2003): 41–57. http://dx.doi.org/10.1080/1062936021000058773.

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4

Tavio, M. M., G. A. Jacoby, and D. C. Hooper. "QnrS1 structure-activity relationships." Journal of Antimicrobial Chemotherapy 69, no. 8 (2014): 2102–9. http://dx.doi.org/10.1093/jac/dku102.

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5

Lavelle, F. "Taxoids: Structure-activity relationships." Pharmacological Research 31 (January 1995): 23. http://dx.doi.org/10.1016/1043-6618(95)86351-6.

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6

Basketter, D. A. "Quantitative structure-activity relationships." Toxicology in Vitro 3, no. 4 (1989): 351–53. http://dx.doi.org/10.1016/0887-2333(89)90044-1.

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7

Bottalico, Antonio, Renato Capasso, Antonio Evidente, Giacomino Randazzo, and Maurizio Vurro. "Cytochalasins: Structure-activity relationships." Phytochemistry 29, no. 1 (1990): 93–96. http://dx.doi.org/10.1016/0031-9422(90)89018-5.

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8

Carroll, F. Ivy. "Epibatidine structure–activity relationships." Bioorganic & Medicinal Chemistry Letters 14, no. 8 (2004): 1889–96. http://dx.doi.org/10.1016/j.bmcl.2004.02.007.

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9

Kim, Pilho, Sunhee Kang, Helena I. Boshoff, et al. "Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships." Journal of Medicinal Chemistry 52, no. 5 (2009): 1329–44. http://dx.doi.org/10.1021/jm801374t.

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10

Jacob, Vaya, Tavori Hagai, and Khatib Soliman. "Structure-Activity Relationships of Flavonoids." Current Organic Chemistry 15, no. 15 (2011): 2641–57. http://dx.doi.org/10.2174/138527211796367309.

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11

Etayash, Hashem, Sarfuddin Azmi, Ramana Dangeti, and Kamaljit Kaur. "Peptide Bacteriocins - Structure Activity Relationships." Current Topics in Medicinal Chemistry 16, no. 2 (2015): 220–41. http://dx.doi.org/10.2174/1568026615666150812121103.

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12

Wu, Qinghua, Vlastimil Dohnal, Kami Kuca, and Zonghui Yuan. "Trichothecenes: Structure-Toxic Activity Relationships." Current Drug Metabolism 14, no. 6 (2013): 641–60. http://dx.doi.org/10.2174/1389200211314060002.

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13

WALKER, ROBERT JAMES, VITTORIA AMALIA LAZZARO, GEOFFREY GORDON DUGGIN, JOHN STEPHEN HORVATH, and DAVID JOHN TILLER. "STRUCTURE-ACTIVITY RELATIONSHIPS OF CYCLOSPORINES." Transplantation 48, no. 2 (1989): 321–27. http://dx.doi.org/10.1097/00007890-198908000-00026.

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14

Jordan, V. C., S. Mittal, B. Gosden, R. Koch, and M. E. Lieberman. "Structure-activity relationships of estrogens." Environmental Health Perspectives 61 (September 1985): 97–110. http://dx.doi.org/10.1289/ehp.856197.

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15

Omura, S., H. Sano, and T. Sunazuka. "Structure activity relationships of spiramycins." Journal of Antimicrobial Chemotherapy 16, suppl A (1985): 1–11. http://dx.doi.org/10.1093/jac/16.suppl_a.1.

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16

Berntsson, Peder, Erik Johansson, and Christer Westerlund. "Felodipine Analogs: Structure-Activity Relationships." Journal of Cardiovascular Pharmacology 10 (1987): S60—S65. http://dx.doi.org/10.1097/00005344-198710001-00011.

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17

Razdan, R. K. "Structure-activity relationships in cannabinoids." Pharmacological Reviews 38, no. 2 (1986): 75–149. https://doi.org/10.1016/s0031-6997(25)06863-2.

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18

Matsubara, Satoshi. "Structure‐activity relationships of cytokinins." Critical Reviews in Plant Sciences 9, no. 1 (1990): 17–57. http://dx.doi.org/10.1080/07352689009382281.

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19

González-Coloma, Azucena, Ana Guadaño, Carmen Gutiérrez, et al. "AntifeedantDelphiniumDiterpenoid Alkaloids. Structure−Activity Relationships." Journal of Agricultural and Food Chemistry 46, no. 1 (1998): 286–90. http://dx.doi.org/10.1021/jf970585p.

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20

Kimura, Sadao, Yoshitoshi Kasuya, Tatsuya Sawamara, et al. "Structure-activity relationships of endothelin." Japanese Journal of Pharmacology 49 (1989): 316. http://dx.doi.org/10.1016/s0021-5198(19)56785-3.

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21

Arcos, Joseph C. "ES Views: Structure-activity relationships." Environmental Science & Technology 21, no. 8 (1987): 743–45. http://dx.doi.org/10.1021/es00162a002.

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22

Betina, Vladimír. "Structure-activity relationships among mycotoxins." Chemico-Biological Interactions 71, no. 2-3 (1989): 105–46. http://dx.doi.org/10.1016/0009-2797(89)90030-6.

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23

Birch, G. G., and S. Shamil. "Structure/activity relationships in sweetness." Food Chemistry 21, no. 4 (1986): 245–58. http://dx.doi.org/10.1016/0308-8146(86)90061-0.

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24

Yuzhakov, S. D., R. G. Glushkov, and M. D. Mashkovskii. "Structure-activity relationships in ?-adrenoblockers." Pharmaceutical Chemistry Journal 25, no. 5 (1991): 283–95. http://dx.doi.org/10.1007/bf00772116.

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25

Dunn, W. J. "Quantitative structure—activity relationships (QSAR)." Chemometrics and Intelligent Laboratory Systems 6, no. 3 (1989): 181–90. http://dx.doi.org/10.1016/0169-7439(89)80083-8.

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26

Nielsen, S., A. Andersen, C. Olsen, M. Treimann, O. Thastrup, and S. Christensen. "Structure-Activity Relationships of Thapsigargin." Planta Medica 59, S 1 (1993): A678—A679. http://dx.doi.org/10.1055/s-2006-959958.

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27

Marshall, Garland R., and Richard D. Cramer. "Three-dimensional structure-activity relationships." Trends in Pharmacological Sciences 9, no. 8 (1988): 285–89. http://dx.doi.org/10.1016/0165-6147(88)90012-0.

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28

Morley, John O., and Thomas P. Matthews. "Structure–activity relationships in nitrothiophenes." Bioorganic & Medicinal Chemistry 14, no. 23 (2006): 8099–108. http://dx.doi.org/10.1016/j.bmc.2006.07.032.

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29

Clark-Lewis, Ian, Key-Sun Kim, Krishnakumar Rajarathnam, et al. "Structure-activity relationships of chemokines." Journal of Leukocyte Biology 57, no. 5 (1995): 703–11. http://dx.doi.org/10.1002/jlb.57.5.703.

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30

Barnard, Jonathan H, Jonathan C Collings, Andrew Whiting, Stefan A Przyborski, and Todd B Marder. "Synthetic Retinoids: Structure-Activity Relationships." Chemistry - A European Journal 15, no. 43 (2009): 11430–42. http://dx.doi.org/10.1002/chem.200901952.

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31

Almi, Zineb, Salah Belaidi, Nadjib Melkemi, Salima Boughdiri, and Lotfi Belkhiri. "Structure Activity Relationship and Quantitative Structure-Activity Relationships Modeling of Cyto-Toxicity of Phenothiazine Derivatives." Quantum Matter 5, no. 1 (2016): 124–29. http://dx.doi.org/10.1166/qm.2016.1264.

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32

Kim, Pilho, Sunhee Kang, Helena I. Boshoff, et al. "Corrections to Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships." Journal of Medicinal Chemistry 52, no. 18 (2009): 5770. http://dx.doi.org/10.1021/jm901277v.

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33

Iwasa, Kinuko, Hiroaki Nanba, Dong-Ung Lee, and So-lm Kang. "Structure-Activity Relationships of Protoberberines Having Antimicrobial Activity." Planta Medica 64, no. 08 (1998): 748–51. http://dx.doi.org/10.1055/s-2006-957572.

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34

Grassy, G., J. Fagart, B. Calas, M. Adenot, ME Rafestin-Oblin, and G. Auzou. "Structure-activity relationships of steroids with mineralocorticoid activity." European Journal of Medicinal Chemistry 32, no. 11 (1997): 869–79. http://dx.doi.org/10.1016/s0223-5234(97)82772-9.

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35

Luthria, Devanand Lakshmichand, Vijayaraghavan Ramakrishnan, and Asoke Banerji. "Insect Antifeedant Activity of Furochromones: Structure-Activity Relationships." Journal of Natural Products 56, no. 5 (1993): 671–75. http://dx.doi.org/10.1021/np50095a002.

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36

Shimazaki, Norihiko, Ichiro Shima, Masanori Okamoto, Keizo Yoshida, Keiji Hemmi, and Masashi Hashimoto. "PAF inhibitory activity of diketopiperazines: Structure-activity relationships." Lipids 26, no. 12 (1991): 1175–78. http://dx.doi.org/10.1007/bf02536526.

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37

Iyer, Preeti, Dagmar Stumpfe, Martin Vogt, J. Bajorath, and G. M. Maggiora. "Activity Landscapes, Information Theory, and Structure - Activity Relationships." Molecular Informatics 32, no. 5-6 (2013): 421–30. http://dx.doi.org/10.1002/minf.201200120.

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38

Cechinel Filho, Valdir, Obdúlio Gomes Miguel, Ricardo José Nunes, João Batista Calixto, and Rosendo Augusto Yunes. "Antispasmodic Activity of Xanthoxyline Derivatives: Structure–Activity Relationships." Journal of Pharmaceutical Sciences 84, no. 4 (1995): 473–75. http://dx.doi.org/10.1002/jps.2600840416.

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39

Lu, Xu, and Yang Qin. "Artificial Intelligence and Big Data Analysis of Electron Cloud Density." Research & Reviews: Journal of Chemistry 12, no. 2 (2023): 7. https://doi.org/10.4172/2319-9849.12.2.001.

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This review tries to explain about a new Quantitative Structure-Activity Relationship (QSAR) method, Deep Electron Cloud-Activity Relationships (DECAR) and Deep Field-Activity Relationships (DFAR). It also outlooks the prospects of the international Lab for Molecular Deep Electron Cloud-activity Relationships (LabMolDECAR) under development in Tongren University. It is one of the core tasks for chemists to investigate the properties and activities for millions of chemical molecules with diverse structures.
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40

Oganesyan, �. T., I. M. Dubrovkin, V. I. Yakovenko, S. R. Pershkov, and Yu A. Sanakoev. "Structure-activity relationships in flavonoids. 2. Structure-activity correlations in chalcones." Pharmaceutical Chemistry Journal 21, no. 2 (1987): 134–39. http://dx.doi.org/10.1007/bf00765115.

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41

Belaidi, Salah, Toufik Salah, Nadjib Melkemi, Leena Sinha, and Onkar Prasad. "Structure Activity Relationship and Quantitative Structure-Activity Relationships Modeling of Antitrypanosomal Activities of Alkyldiamine Cryptolepine Derivatives." Journal of Computational and Theoretical Nanoscience 12, no. 9 (2015): 2421–27. http://dx.doi.org/10.1166/jctn.2015.4042.

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42

A, BrándstRöm, Lindberg P, and Junggren U. "Structure activity relationships of substituted benzimidazoles." Scandinavian Journal of Gastroenterology 20, sup108 (1985): 15–22. http://dx.doi.org/10.3109/00365528509095816.

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43

Brändström, Arne, Per Lindberg, Ulf Junggren, and Björn Wallmark. "Structure-Activity Relationships of Substituted Benzimidazoles." Scandinavian Journal of Gastroenterology 21, sup118 (1986): 54–56. http://dx.doi.org/10.3109/00365528609090890.

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44

Mustafaev, Orkhan N., Serikbay K. Abilev, Viktor A. Melnik, and Valentin A. Tarasov. "Structure-activity relationships of antimutagenic flavonoids." Ecological genetics 3, no. 4 (2005): 11–18. http://dx.doi.org/10.17816/ecogen3411-18.

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Influence of structural features of molecules on antimutagenic activity of flavonoids is investigated. For this purpose the new principle of the description of dependence of biological activity of chemical compounds from their structure is used. It is based on use compound descriptors. It is established, that antimutagenic flavonoids contains C4 keto-group and doubl bond at positions C2 and C3, contains hydroxyl groups. Thus in structure of antimutagenic flavonoids can not be amino-and nitrogroups.
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45

Hasdenteufel, Frederic, Samuel Luyasu, Nicolas Hougardy, et al. "Structure-Activity Relationships and Drug Allergy." Current Clinical Pharmacology 7, no. 1 (2012): 15–27. http://dx.doi.org/10.2174/157488412799218815.

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46

Morley, John O., A. Jayne Oliver Kapur, and Michael H. Charlton. "Structure–activity relationships in 3-isothiazolones." Organic & Biomolecular Chemistry 3, no. 20 (2005): 3713. http://dx.doi.org/10.1039/b509529h.

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47

Campopiano, Dominic J., David J. Clarke, Nick C. Polfer, et al. "Structure-Activity Relationships in Defensin Dimers." Journal of Biological Chemistry 279, no. 47 (2004): 48671–79. http://dx.doi.org/10.1074/jbc.m404690200.

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48

Voutquenne, Laurence, Catherine Lavaud, Georges Massiot, and Louisette Le Men-Olivier. "Structure-Activity Relationships of Haemolytic Saponins." Pharmaceutical Biology 40, no. 4 (2002): 253–62. http://dx.doi.org/10.1076/phbi.40.4.253.8470.

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49

BASKETTER, D. A., and D. W. ROBERTS. "Structure/activity relationships in contact allergy." International Journal of Cosmetic Science 12, no. 2 (1990): 81–90. http://dx.doi.org/10.1111/j.1467-2494.1990.tb00523.x.

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50

Chu, D. T., and P. B. Fernandes. "Structure-activity relationships of the fluoroquinolones." Antimicrobial Agents and Chemotherapy 33, no. 2 (1989): 131–35. http://dx.doi.org/10.1128/aac.33.2.131.

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