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Relevant bibliographies by topics / Structure-based development

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Academic literature on the topic 'Structure-based development'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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Journal articles on the topic "Structure-based development"

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Cui, Xin. "Structure design of knowledge base of software enterprise based on project development." Functional materials 24, no. 2 (June 22, 2017): 005–284. http://dx.doi.org/10.15407/fm24.02.278.

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Faig, Margarita, Mario A. Bianchet, Shannon Winski, Robert Hargreaves, Christopher J. Moody, Anna R. Hudnott, David Ross, and L. Mario Amzel. "Structure-Based Development of Anticancer Drugs." Structure 9, no. 8 (August 2001): 659–67. http://dx.doi.org/10.1016/s0969-2126(01)00636-0.

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Malito, Enrico. "Structure-based Vaccine Development (Structural Vaccinology)." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C697. http://dx.doi.org/10.1107/s2053273314093024.

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Structural biology is playing an increasingly important role in vaccine development, as it can facilitate the rational design of vaccines by allowing an atomic-level control of their antigenic and immunogenic properties. Several cases are now available that demonstrate the potential of structure-based methods for vaccine development. Here, I will present an overview of the insights we gained at Novartis Vaccines from studying two protein antigens of the recently approved vaccine against serogroup B meningococcus (MenB), and their impact for vaccine design and development. MenB causes severe sepsis and invasive meningococcal disease (IMD), particularly affecting young children and adolescents. In 2013, the first genome-derived vaccine, which targets MenB (4CMenB), was approved for use in Europe, and it is expected to become widely implemented in Europe beginning in 2014. The vaccine contains 3 previously unknown recombinant proteins discovered by genome mining. For one of the antigens, Factor H Binding Protein (FHBP), we recently generated a broadly protective chimera by a structure-based approach that consisted in grafting multiple immunodominant regions onto a single scaffold. Also, co-crystal structures of FHBP with Fabs from monoclonal antibodies provided insights into the molecular bases of the immune recognition and bactericidal activity. The structure of a second antigen, Neisserial adhesin A (NadA), a member of the Trimeric Autotransporter Adhesins (TAA), revealed a novel fold, while epitope mapping by Hydrogen-Deuterium Exchange Mass Spectrometry showed that in addition to being the receptor-binding domain, the head domain of NadA is also the target of a bactericidal monoclonal antibody. Overall, the structural information on the MenB antigens presented here provides important details on the pathogenesis and vaccine-induced immunity against meningococcus, and especially informs the engineering of improved immunogens by structure-based design.

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Martín-Gago, Pablo, Eyad Kalawy Fansa, Alfred Wittinghofer, and Herbert Waldmann. "Structure-based development of PDEδ inhibitors." Biological Chemistry 398, no. 5-6 (May 1, 2017): 535–45. http://dx.doi.org/10.1515/hsz-2016-0272.

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Abstract The prenyl binding protein PDEδ enhances the diffusion of farnesylated Ras proteins in the cytosol, ultimately affecting their correct localization and signaling. This has turned PDEδ into a promising target to prevent oncogenic KRas signaling. In this review we summarize and describe the structure-guided-development of the three different PDEδ inhibitor chemotypes that have been documented so far. We also compare both their potency for binding to the PDEδ pocket and their in vivo efficiency in suppressing oncogenic KRas signaling, as a result of the inhibition of the PDEδ/KRas interaction.

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Chen, Guo-fang, Ting-hai Xu, Yan Yan, Yu-ren Zhou, Yi Jiang, Karsten Melcher, and H. Eric Xu. "Amyloid beta: structure, biology and structure-based therapeutic development." Acta Pharmacologica Sinica 38, no. 9 (July 17, 2017): 1205–35. http://dx.doi.org/10.1038/aps.2017.28.

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Schlicker, Christine, Gina Boanca, Mahadevan Lakshminarasimhan, and Clemens Steegborn. "Structure-based development of novel sirtuin inhibitors." Aging 3, no. 9 (September 20, 2011): 852–72. http://dx.doi.org/10.18632/aging.100388.

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Saggaf, Said. "Policy impact of regional development based on local potential toward the economic structure of Bantaeng Regency." International Journal of Academic Research 6, no. 1 (January 30, 2014): 89–93. http://dx.doi.org/10.7813/2075-4124.2014/6-1/b.13.

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Zhang, Yingqun, Rui Song, Rob van Nes, Shiwei He, and Weichuan Yin. "Identifying Urban Structure Based on Transit-Oriented Development." Sustainability 11, no. 24 (December 17, 2019): 7241. http://dx.doi.org/10.3390/su11247241.

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The fast development of urbanization has led to imbalances in cities, causing congestion, pollution, and urban sprawl. In response to the growing concern over the distribution of demand and supply, a more coordinated urban structure is addressed in comprehensive planning processes. In this study, we attempt to identify urban structure using a Network–Activity–Human model under the Transit-Oriented Development (TOD) concept, since TOD is usually regarded as an urban spatial planning tool. In order to explore the strengths and weaknesses of the urban structure, we define the TOD index and unbalance degree and then classify the urban areas accordingly. We take the city of Beijing as a case study and identify nine urban types. The results show a hierarchical urban structure: the city center covers most of the hotspots which display higher imbalances, the surroundings of the city center are less developed, and the city edges show higher potentials in both exploitation and transportation development. Moreover, we discuss the extent to which the spatial scale influences the unbalance degree and apply a sensitivity analysis based on the goals of different stakeholders. This methodology could be utilized at any study scale and in any situation, and the results could offer suggestions for more accurate urban planning, strengthening the relationship between TOD and spatial organization.

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Tedeschi, L. O., R. R. White, C. F. Nicholson, B. L. Turner, M. A. Fonseca, and M. D. Hanigan. "1294 Traditional versus structure-based model development strategies." Journal of Animal Science 94, suppl_5 (October 1, 2016): 624. http://dx.doi.org/10.2527/jam2016-1294.

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Orry, Andrew J. W., Ruben A. Abagyan, and Claudio N. Cavasotto. "Structure-based development of target-specific compound libraries." Drug Discovery Today 11, no. 5-6 (March 2006): 261–66. http://dx.doi.org/10.1016/s1359-6446(05)03717-7.

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Dissertations / Theses on the topic "Structure-based development"

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Ravn, Jacob. "Development of privileged structure based libraries /." Måløv ; Cph. : Medicinal Chemistry Research III, Novo Nordisk A/S og Department of Medicinal Chemistry : The Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/jacobravn.htm.

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Mezulis, Stefans. "Development of novel strategies for template-based protein structure prediction." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/48482.

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The most successful methods for predicting the structure of a protein from its sequence rely on identifying homologous sequences with a known structure and building a model from these structures. A key component of these homology modelling pipelines is a model combination method, responsible for combining homologous structures into a coherent whole. Presented in this thesis is poing2, a model combination method using physics-, knowledge- and template-based constraints to assemble proteins using information from known structures. By combining intrinsic bond length, angle and torsional constraints with long- and short-range information extracted from template structures, poing2 assembles simplified protein models using molecular dynamics algorithms. Compared to the widely-used model combination tool MODELLER, poing2 is able to assemble models of approximately equal quality. When supplied only with poor quality templates or templates that do not cover the majority of the query sequence, poing2 significantly outperforms MODELLER. Additionally presented in this work is PhyreStorm, a tool for quickly and accurately aligning the three-dimensional structure of a query protein with the Protein Data Bank (PDB). The PhyreStorm web server provides comprehensive, current and rapid structural comparisons to the protein data bank, providing researchers with another tool from which a range of biological insights may be drawn. By partitioning the PDB into clusters of similar structures and performing an initial alignment to the representatives of each cluster, PhyreStorm is able to quickly determine which structures should be excluded from the alignment. For a benchmarking set of 100 proteins of diverse structure, PhyreStorm is capable of finding over 90% of all high-scoring structures in the PDB, and over 80% of all structures of moderate alignment score.

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Rogers, Graeme W. "The development of sialidase inhibitors using structure-based drug design." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/15516.

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The sialidases/neuraminidases represent a family of enzymes whose function is important in the pathogenicity of bacteria and the virulence of influenza. Relenza and Tamiflu represent two drugs that were developed using structure-based drug design (SBDD) and computational-assisted drug design (CADD). These drugs target the active site of the influenza neuraminidase A and B (GH-34 family). Sialidases in the GH-33 family could represent novel drug targets for the treatment of bacterial or parasitic infection. SBDD was employed to develop chemical tools of two GH-33 sialidases, NanB and TcTS. NanB is a potential drug target for S. pneumoniae. The chemical tool developed for NanB follows on from work within the Taylor and Westwood research groups, in which a molecule of CHES and a glycerol were found serendipitously bound within a water channel at an allosteric site. Using this information as a basis for SBDD an allosteric inhibitor of NanB, Optactin was developed. Within this work, synthesis of this inhibitor was achieved and optimised. Optactin was then modified to improve potency. This proceeded through an amide analogue and addition of an arene resulting in a mid- micromolar inhibitor (IC50: 55.4±2.5 μM). Addition of polar substituents improved potency further resulting in a low micromolar inhibitor of NanB, Optactamide (IC50: 3.0±1.7 μM). Application of this tool in vitro demonstrated that NanB and NanA have a role in invasion of S. pneumoniae into lung epithelial cells. TcTS is a potential drug target for the treatment of Chagas disease. A CADD approach using a fragment library was unsuccessful at identifying an allosteric inhibitor of TcTS despite structural similarity with NanB. A re-task of the CADD approach towards the active site was successful in identifying an inhibitor of TcTS and a fragment useful for further development. This work sets the groundwork for the development of a chemical tool targeting TcTS.

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Shave, Steven R. "Development of high performance structure and ligand based virtual screening techniques." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4333.

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Virtual Sreening (VS) is an in silico technique for drug discovery. An overview of VS methods is given and is seen to be approachable from two sides: structure based and ligand based. Structure based virtual screening uses explicit knowledge of the target receptor to suggest candidate receptor-ligand complexes. Ligand based virtual screening can infer required characteristics of binders from known ligands. A consideration for all virtual screening techniques is the amount of computing time required to arrive at a solution. For this reason, techniques of high performance computing have been applied to both the structural and ligand based approaches. A proven structure based virtual screening code LIDAEUS (Ligand Discovery At Edinburgh University) has been ported and parallelised to a massively parallel computing platform, the University of Edinburgh’s IBM Bluegene/l, consisting of 2,048 processor cores. A challenge in achieving scaling to such a large number of processors required implementation of a minimal communication parallel sort algorithm. Parallel efficiencies achieved within this parallelisation exceeded 99%, confirming that a near optimum strategy has been followed and capacity for running the code on a greater number of processors exists. This implementation of the program has been successfully used with a number of protein targets. The development of a new ligand based virtual screening code has been completed. The program UFSRAT (Ultra Fast Shape Recognition with Atom Types) takes the features of known binders and suggests molecules which will be able to make similar interactions. This similarity method is both fast (1 million molecules per hour per processor) and independent of input orientation. Along with UFSRAT, some other methods (VolRAT and UFSRGraph) based on UFSRAT have been developed, addressing different approaches to ligand based virtual screening. UFSRAT as an approach to discovering novel protein-ligand complexes has been validated with the discovery of a number of inhibitors for 11β-Hydroxysteroid Dehydrogenase type 1 and FK binding protein 12.

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Heikkila, Timo Johannes. "Class 2 dihydroorate dehydrogenases : biochemical characterisation and structure-based inhibitor development." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444060.

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Chimni, Jasbinder Singh Carleton University Dissertation Management Studies. "An approach to computer-based support for work breakdown structure development." Ottawa, 1989.

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He, Jianhao. "The development of structure-based tidal stream turbine condition monitoring systems." Thesis, Cardiff University, 2018. http://orca.cf.ac.uk/111196/.

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The research presented considers the design, development and building of a structure-based condition monitoring system. A series of physical experiments were designed and conducted in a wind tunnel. This was able to initially prove the feasibility of the proposed system. Using a simulation of the continuous turbine rotation the self-initiated Phase-Angle curve was defined. The algorithms so produced were validated and tested using both the simulated waveforms and experimental data sets. This demonstrated that the proposed monitoring system was able to deal with the ever-changing flow conditions and turbine operation status. The work showed that the use of the wind tunnel was feasible for developing the structure-based monitoring system. It has been shown that innovative ideas can be tested and validated in the wind tunnel. The relatively small size of the test rig and the utility of 3-D printing technology made the whole experiment based investigation very cost-effective. The progressive experiments were conducted to compare widely used monitoring techniques to the proposed monitoring system. Some other physical phenomenon or extended thoughts such as blade tip deflection caused by the tower were considered and may be of interest to other researchers. The final discussion of the work presented was to introduce the potential problems and difficulties in applying the proposed system in the marine environment. This considered the sensor design, system installation, application methods and algorithm optimisation. This could further serve the useful information for the relevant researchers and the experiment or deployment of the proposed system on full-size turbine.

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Bhat, Sathesh. "Development and application of novel computational tools for structure based drug design." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18425.

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Computational structure-based methods represent valuable tools in the drug design pipeline, as evidenced by their widespread use. This thesis describes five research projects that represent important computational advances in the methodologies and protocols of lead discovery and optimization. The first project demonstrates that the current paradigm of utilizing a fixed 1.4 Å solvent probe radius when generating the molecular surface results in unrealistic hydrophobic cavities and pockets on the surface. A novel method is developed which allows the solvent probe to change size according to its contacting atoms on the surface, thereby producing a more accurate representation of protein clefts, pockets and cavities, as well as giving a better tuned description of shape complementarity and electrostatic energies. The second project demonstrates that utilizing hydration parameters for calculation of electrostatic binding free energies results in a large mean error between predicted and experimental binding affinities. Consequently, a novel solvated interaction energy (SIE) scoring function is developed that parameterizes the electrostatic model using experimental binding data. The SIE scoring function is able to reproduce the affinities of 99 varied ligand-protein complexes with a mean error of 1.29 kcal/mol. In the third project, the SIE scoring function is incorporated into a novel virtual screening (VS) pipeline. The discriminative power of the SIE function is improved by including terms that account for entropy and hydrogen bonding. The resulting VS pipeline outperforms the majority of other VS methodologies in the literature. In the fourth project, a modified version of the VS pipeline is employed to predict the binding mode of a glycopeptide antibiotic to the bacterial sulfotransferase StaL. The predicted binding mode is in good agreement with experimental findings. In the fifth project, a novel method to compute electrostatic optimal charge selectivity, termed
Les méthodes de modélisation basées sur la structure tridimensionnelle des protéines sont d'une grande utilité dans le développement de médicaments. Cette thèse résume cinq projets de recherche proposant des avancées dans la méthodologie et les protocoles liés à la découverte et à l'optimisation de petites molécules actives. Le premier projet démontre que le paradigme voulant que la surface moléculaire exposée au solvant soit décrite par le contact d'une sonde sphérique de rayon constant de 1.4Å avec la protéine fait apparaître des poches et des cavités hydrophobes irréalistes sur la surface. Une méthode novatrice est présentée où le rayon de la sonde change au contact des différents types d'atome produisant ainsi une représentation plus réaliste des aspérités de la surface ayant pour effet une meilleure définition de la complémentarité de la forme moléculaire ainsi qu'une meilleure estimation de l'énergie électrostatique. Le deuxième projet démontre que l'utilisation d'un simple coefficient d'hydratation pour corriger le calcul de l'énergie libre de liaison entraîne une erreur moyenne importante entre les affinités calculées et mesurées expérimentalement. Conséquemment, une nouvelle fonction d'énergie tenant compte de la solvatation (SIE) a été développée appuyant sa paramétrisation sur des données expérimentales. La fonction SIE est en mesure de reproduire les affinités de 99 complexes ligand-protéine différents avec une erreur moyenne de 1.29 kcal/mol. Dans le troisième projet, la fonction SIE est introduite dans une nouvelle procédure de criblage virtuel (CV). La capacité de la fonction SIE est accrue par l'ajout d'un terme d'entropie et d'un terme décrivant les liaisons hydrogène. La procédure de criblage qui en résulte déclasse la majorité des autres méthodes publiées. Dans le quatrième projet une version modifiée de la procédure de criblage est utilisée pour prédire les modes de

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Kumar, Yadhu. "Development and integration of structure based visualization tools in ARB software package." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=978967372.

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Stathaki, Marika. "Development of a computer-based package for interactive learning of structure contours /." Leeds, 2001. http://www.leeds.ac.uk/library/counter2/compstmsc/20002001/stathaki.pdf.

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Books on the topic "Structure-based development"

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Barlow, Richard. The development of team-based organization structure in public libraries in England, 1969-1986. Boston Spa: The British Library, Document Supply Centre, 1987.

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Sinha, Frances. From indifference to active participation: Six case studies of natural development through social organisation. Gurgaon: EDA Rural Systems, 1996.

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Schlabrendorff, Fabian von. The legal structure of transnational forest-based investments in developing countries: A comparative study of the contractual practice in selected host countries of the tropical Asia-Pacific region. Zürich: ETH Zürich, 1987.

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Straalen, Nico, and Dick Roelofs. Human Evolution and Development. NL Amsterdam: Amsterdam University Press, 2019. http://dx.doi.org/10.5117/9789463729208.

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Our understanding of human evolution is proceeding at an unprecedented rate over the last years due to spectacular fossil finds, reconstructions based on genome comparison, ancient DNA sequencing and new insights into developmental genetics. This book takes an integrative approach in which the development of the human embryo, the evolutionary history of our body, the structure of human populations, their dispersal over the world and their cultures are examined by integrating paleoanthropology, developmental biology, comparative zoology, population genetics and phylogenetic reconstruction. The authors discuss questions like: - What do we know about ancient humans? - What happens in the development of an embryo? - How did we manage to walk upright and why did we lose our hair? - What is the relationship between language, migration and evolution? - How does our body respond to the challenges of modern society? In addition to being a core text for the study of the life sciences, Human Evolution and Development is an easy-to-read overview for the interested layperson.

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Cevelev, Aleksandr. Strategic development of railway transport logistics. ru: INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1194747.

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The monograph is devoted to the methodology of material and technical support of railway transport. According to the types of activities, the nature of the material and technical resources used, technologies, means and management systems, Russian railways belong to the category of high-tech industries that must have high quality and technical level, reliability and technological efficiency in operation. For this reason, the logistics system itself, both in structure and in the algorithm of the functions performed as a whole, needs a serious improvement in the quality of its work. The economic situation in Russia requires a revision of the principles and mechanisms of management based on the corporate model of supply chain management, focused on logistics knowledge. In the difficult economic conditions of the current decade, it is necessary to improve the quality of the supply organization of enterprises and structural divisions of railway transport, directly related to the implementation of the process approach, the advantage of which is a more detailed regulation of management actions and their mutual coordination. In order to increase the efficiency of its activities and develop the management system, Russian Railways is developing a lean production system aimed at further expanding the implementation of the principles of customer orientation, ideology and corporate culture. At the present time, the solution of many issues is impossible without a cybernetic approach to the formulation of problems of material and technical support and logistics analysis of information technologies, to the implementation of the developed algorithms and models of development strategies and concepts for improving the business processes of the production system. The management strategy, or the general plan for the implementation of activities for the management of material resources, is based on a fundamental assessment of the alignment and correlation of forces and factors operating in the economic and political field, taking into account the impact on the specific form of the management strategy. The materials will be useful to the heads and specialists of the directorates of the MTO, CDZs and can be used in the scientific research of bachelors, masters and postgraduates interested in the economics of railway transport and supply logistics.

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Kumar, P. Sai. Development of windows based application for the calculation of atomic hyperfine spectrum of ODD isotopes. Mumbai: Bhabha Atomic Research Centre, 2002.

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Du, Qishi. Developments in structure-based theoretical modeling of hydrophobicity for computer-aided drug design. Sudbury, Ont: Laurentian University Press, 1995.

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Hvostova, Irina, Aleksey Makarov, and Aleksandr Larin. Non-financial factors in the formation of the company's financial policy: composition, structure, relationships. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1080130.

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When implementing the financial policy of the Corporation, the object of attention of owners and managers is increasingly becoming non-financial indicators of the development of modern companies, such as corporate governance characteristics, socio-economic and environmental indicators. Without denying the need to calculate and analyze financial and economic criteria for evaluating the effectiveness of financial policy, the authors of the monograph describe and systematize the composition and structure of non-financial factors of financial policy, based on the theory of Agency relations and the concept of sustainable development. Along with the theoretical analysis of non-financial factors of financial policy formation, the monograph presents the results of their empirical analysis for emerging markets, as well as an empirical analysis of trends in the use of non-financial indicators in modern corporate Finance research. It is intended for a wide range of readers, including researchers, practitioners, postgraduates, applicants and students studying in the fields of "Economics", "Management".

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Baryshev, R., Mihail Noskov, and Margarita Manushkina. Electronic library in the context of the electronic information and educational environment of the University. ru: INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/24242.

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The monograph examines the structure and functions of the electronic information and educational environment of the University and the place of the electronic library in this structure. The analysis of literary sources is carried out and the most important directions of development of University electronic libraries are highlighted. Based on the analysis, a model for the development of the library of a modern University is proposed. For students, postgraduates, teachers, and anyone interested in library systems.

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Grassini, Maurizio, and Rossella Bardazzi, eds. Structural changes, international trade and multisectoral modelling. Florence: Firenze University Press, 2008. http://dx.doi.org/10.36253/978-88-8453-740-9.

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In September 2007 the national team members of the International Inforum (Interindustry Forecasting Project at the University of Maryland) group held the XV annual World Conference in Truijllo, Spain. Such Conferences offer the participants to report their achievements in the different fields concerning the macroeconomic multisectoral modeling approach and data development. The national partners build their country model based on a common input-output accounting structure and a similar econometric modeling approach for sectoral and macroeconomic variables. In each Conference, the contributions refer to the wide spectrum of research activities carried on within the Inforum system of models.

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Book chapters on the topic "Structure-based development"

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Canan, Stacie S. "Structure Based Design of PARP Inhibitors." In Cancer Drug Discovery and Development, 205–21. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14151-0_8.

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Thomas, Sunil. "Development of Structure-Based Vaccines for Ehrlichiosis." In Vaccine Design, 519–34. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3387-7_29.

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Abramowicz, Witold, and Dariusz Ceglarekt. "Cluster-Based Connection Structure for SDI Documents." In Evolution and Challenges in System Development, 539–50. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4851-5_49.

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McCoach, D. Betsy, Robert K. Gable, and John P. Madura. "Additional Evidence Based on the Internal Structure of the Instrument." In Instrument Development in the Affective Domain, 163–208. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7135-6_5.

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Ghosh, Arun K., and Sandra Gemma. "Development of Direct Thrombin Inhibitor, Dabigatran Etexilate, as an Anticoagulant Drug." In Structure-Based Design of Drugs and Other Bioactive Molecules, 337–54. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2015. http://dx.doi.org/10.1002/9783527665211.ch15.

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McCoach, D. Betsy, Robert K. Gable, and John P. Madura. "Evidence Based on the Internal Structure of the Instrument: Factor Analysis." In Instrument Development in the Affective Domain, 109–61. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7135-6_4.

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Dean, Barbara A., Melanie Chichester, Laurie Hewlett-Miller, Vanita D. Jain, Erin M. Denney-Koelsch, and Michael L. Spear. "Structure and Development of Hospital-Based Perinatal Palliative Care Programs." In Perinatal Palliative Care, 279–304. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-34751-2_13.

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Basir, Nurlida, Ewen Denney, and Bernd Fischer. "Deriving Safety Cases for Hierarchical Structure in Model-Based Development." In Lecture Notes in Computer Science, 68–81. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-15651-9_6.

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Zhang, Qing, Zhipeng Xie, Weiwei Sun, and Baile Shi. "Tree Structure Based Data Gathering for Maximum Lifetime in Wireless Sensor Networks." In Web Technologies Research and Development - APWeb 2005, 513–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/978-3-540-31849-1_50.

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Ferscha, A., and J. Johnson. "Performance oriented development of SPMD programs based on task structure specifications." In Parallel Processing: CONPAR 94 — VAPP VI, 53–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/3-540-58430-7_6.

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Conference papers on the topic "Structure-based development"

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Vejmelkova, Eva. "DEVELOPMENT OF POROUS STRUCTURE OF CERAMIC-BASED GEOPOLYMERS." In 18th International Multidisciplinary Scientific GeoConference SGEM2018. STEF92 Technology, 2018. http://dx.doi.org/10.5593/sgem2018v/6.4/s10.084.

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Yoshida, Hitoshi, Norio Ami, Hideki Nagai, Ryutaro Oishi, Ya Xu, and H. Ota. "Development and applications of TiNi-based smart structure." In SPIE's International Symposium on Smart Materials, Nano-, and Micro- Smart Systems, edited by Erol C. Harvey, Derek Abbott, and Vijay K. Varadan. SPIE, 2002. http://dx.doi.org/10.1117/12.469065.

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Kanareykin, A., C. Jing, E. Nenasheva, P. Schoessow, J. G. Power, W. Gai, Carl B. Schroeder, Wim Leemans, and Eric Esarey. "Development of a Ferroelectric Based Tunable DLA Structure." In ADVANCED ACCELERATOR CONCEPTS: Proceedings of the Thirteenth Advanced Accelerator Concepts Workshop. AIP, 2009. http://dx.doi.org/10.1063/1.3080936.

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Johari, N. A., K. Y. Lau, and Z. Abdul-Malek. "Structure of Polypropylene-based Nanocomposites containing Calcium Zirconate." In 2020 IEEE Student Conference on Research and Development (SCOReD). IEEE, 2020. http://dx.doi.org/10.1109/scored50371.2020.9250932.

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Zamazal, Ondřej. "Towards Ontology Exploration based on Path Structure Richness." In 7th International Conference on Knowledge Engineering and Ontology Development. SCITEPRESS - Science and and Technology Publications, 2015. http://dx.doi.org/10.5220/0005603802450250.

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Fan, Xiaonan, Qiyue Li, and Tianqi Wang. "Research on Interaction Between Financial Structure and Industrial Structure Based on Data of Liaoning Province." In 5th International Conference on Social Sciences and Economic Development (ICSSED 2020). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/assehr.k.200331.112.

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Youwei, Zhang, Wang Yonghong, and Liu Xiaochun. "A Method of Program Structure Division Based on Program Understanding." In 2009 International Conference on Computer Technology and Development. IEEE, 2009. http://dx.doi.org/10.1109/icctd.2009.159.

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Cai, Qing Qiu, Hong Gang Cui, and Hao Tang. "Provenance graph query method based on double layer index structure." In GREEN ENERGY AND SUSTAINABLE DEVELOPMENT I: Proceedings of the International Conference on Green Energy and Sustainable Development (GESD 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.4992846.

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Hagarová, Ráchel. "COST STRUCTURE IN SLOVAK STARTUPS BASED ON DEVELOPMENT PHASE." In DOKBAT 2017. Tomas Bata University in Zlín, Faculty of Management and Economics, 2017. http://dx.doi.org/10.7441/dokbat.2017.13.

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Athma Putri Rsoyadi, Alfiani. "Development of Project Based Handouts in Algebra Structure Course." In University of Muhammadiyah Malang's 1st International Conference of Mathematics Education (INCOMED 2017). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/incomed-17.2018.61.

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Reports on the topic "Structure-based development"

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Maslov, Valeriy V. Development of High Strength Thermally Stable Al-based Alloys with Nanocomposite Structure. Fort Belvoir, VA: Defense Technical Information Center, February 2010. http://dx.doi.org/10.21236/ada531026.

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Hanson, Robert. A Structure Based, Solid Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Fort Belvoir, VA: Defense Technical Information Center, June 2000. http://dx.doi.org/10.21236/ada383168.

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Hanson, Robert N. A Structure Based, Solid-Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada407782.

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Hanson, Robert N. A Structure Based, Solid Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada403350.

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Sowa, Patience, Rachel Jordan, Wendi Ralaingita, and Benjamin Piper. Higher Grounds: Practical Guidelines for Forging Learning Pathways in Upper Primary Education. RTI Press, May 2021. http://dx.doi.org/10.3768/rtipress.2021.op.0069.2105.

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To address chronically low primary school completion rates and the disconnect between learners’ skills at the end of primary school and the skills learners need to thrive in secondary school identified in many low- and middle-income countries, more investment is needed to improve the quality of teaching and learning in upper primary grades. Accordingly, we provide guidelines for improving five components of upper primary education: (1) In-service teacher professional development and pre-service preparation to improve and enhance teacher quality; (2) a focus on mathematics, literacy, and core content-area subjects; (3) assessment for learning; (4) high-quality teaching and learning materials; and (5) positive school climates. We provide foundational guiding principles and recommendations for intervention design and implementation for each component. Additionally, we discuss and propose how to structure and design pre-service teacher preparation and in-service teacher training and ongoing support, fortified by materials design and assessment, to help teachers determine where learners are in developmental progressions, move learners towards mastery, and differentiate and support learners who have fallen behind. We provide additional suggestions for integrating a whole-school climate curriculum, social-emotional learning, and school-related gender-based violence prevention strategies to address the internal and societal changes learners often face as they enter upper primary.

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Adeniran, Adedeji, Mma Amara Ekeruche, and Chukwuka Onywkwena. The Role of Social Influence in Enforcing Tax Compliance: Experimental Evidence from Nigeria. Institute of Development Studies (IDS), June 2021. http://dx.doi.org/10.19088/ictd.2021.011.

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Economic development is linked with increased state capacity including the ability to mobilise domestic tax resources. For many developing countries, high levels of informality are a major constraint in this regard. Yet, economic incentives like changing the tax rate or increasing the filling and audit rate can be ineffective in a highly informal economic structure. In this paper, we explore possible roles for behavioural interventions such as sharing information about peers’ tax behaviour to engineer higher tax compliance. Based on an artefactual field experiment among own account workers in Nigeria, we find that information interventions can play an important role in ensuring tax compliance. Specifically, targeting information around what people can directly observe can be a way to improve tax compliance. Providing information on punishment or good practices that appeal to feelings of morality yields higher tax compliance.

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Smith, Adam, Megan Tooker, and Sunny Adams. Camp Perry Historic District landscape inventory and viewshed analysis. Engineer Research and Development Center (U.S.), March 2021. http://dx.doi.org/10.21079/11681/39841.

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The National Historic Preservation Act of 1966 (NHPA) established the National Register of Historic Places (NRHP), which requires federal agencies to address their cultural resources, defined as any prehistoric or historic district, site, building, structure, or object. NHPA section 110 requires federal agencies to inventory and evaluate their cultural resources. Section 106 requires them to determine the effect of federal undertakings on properties deemed eligible or potentially eligible for the NRHP. Camp Perry Joint Training Center (Camp Perry) is located near Port Clinton, Ohio, and serves as an Ohio Army National Guard (OHARNG) training site. It served as an induction center during federal draft periods and as a prisoner of war camp during World War II. Previous work established boundaries for an historic district and recommended the district eligible for the NRHP. This project inventoried and evaluated Camp Perry’s historic cultural landscape and outlined approaches and recommendations for treatment by Camp Perry cultural resources management. Based on the landscape evaluation, recommendations of a historic district boundary change were made based on the small number of contributing resources to aid future Section 106 processes and/or development of a programmatic agreement in consultation with the Ohio State Historic Preservation Office (SHPO).

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Oltarzhevskyi, Dmytro. HISTORICAL FEATURES OF CORPORATE MEDIA FORMATION IN UKRAINE AND IN THE WORLD. Ivan Franko National University of Lviv, February 2021. http://dx.doi.org/10.30970/vjo.2021.49.11067.

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The article examines the world and Ukrainian history of corporate periodicals. The main purpose of this study is to reproduce an objective global picture of the emergence and formation of corporate periodicals, taking into account the business and socio-economic context. Accordingly, its tasks are to compare the conditions and features of corporate media genesis in different countries, to determine the main factors of their development, as well as to clarify the transformations of the terminological apparatus. The research is based on mostly foreign secondary scientific works published from 1915 to the present time. The literature was studied using methods such as overview, historical, functional and thematic analysis, description, and generalization. A systematic approach was used to determine the role and place of each element in the system, as well as to comprehensively consider the object in the general historical context and within the current scientific discourse. The method of systematization made it possible to establish internal and external connections, patterns and contradictions in the development of the object of study. The main historical milestones on this path are identified, examples of the first successful corporate publications and their contribution to business development, public relations, and corporate communications are considered. It was found that corporate media emerged in the mid-nineteenth century spontaneously, on the wave of practical business needs in response to industrialization, company increase, staff growth, and consumer market development. Their appearance preceded the formation of the public relations industry and changed the structure of the information space. The scientific significance of this research is that the historical look at the evolution of corporate media provides an understanding of their place, influence, capabilities, and growing communicative role in the digital age.

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Ivanova, Iryna, and Elena Afanasieva. MODEL OF INTERACTION BETWEEN ADVERTISING, PR AND JOURNALISM. Ivan Franko National University of Lviv, February 2021. http://dx.doi.org/10.30970/vjo.2021.49.11060.

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The article is an overview of the journalism – PR – advertising relationship at the terminological, empirical-analytical and practical levels. It traces the state of the discussion of these correlations in the post-soviet media such as Ukraine. The study describes that domesticating the importance of the appropriate partnership between the three communication technologies. The thesis is that journalism, advertising and PR create a mutual connection that takes place in an atmosphere of PR and advertising permissiveness and deepens with the development of digitalization, Social network development. The present research is based on a comprehensive approach. The inductive and deductive methods are adopted to discuss theoretical materials, and the interdisciplinary research method is used to detect PR-specific features as a philosophy of a new journalism project. The interpretive approach, usually employed to analyze media text as a complex synthetic structure, was also taken into consideration. The analytical method application identified the modern means of substantiating the ideological, esthetical and informative value of brand journalism and spin doctor. The innovative character of modern media as a behavioral strategy in the advertising and PR industry consists in the fact that it is a form of creative production and behavior rather than adapting a specific communication situation. The article examines the main directions of contemporary interactions between PR, advertising and journalism as a media content creation. In this context, it is asserted that advertising, journalism and PR activities can contribute to the creation of media content. At some point, good media content is achieved not only as a result of this competition but also from the correlation between PR, advertising and journalism.

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Murphy, Joe J., Michael A. Duprey, Robert F. Chew, Paul P. Biemer, Kathleen Mullan Harris, and Carolyn Tucker Halpern. Interactive Visualization to Facilitate Monitoring Longitudinal Survey Data and Paradata. RTI Press, May 2019. http://dx.doi.org/10.3768/rtipress.2019.op.0061.1905.

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Surveys often require monitoring during data collection to ensure progress in meeting goals or to evaluate the interim results of an embedded experiment. Under complex designs, the amount of data available to monitor may be overwhelming and the production of reports and charts can be costly and time consuming. This is especially true in the case of longitudinal surveys, where data may originate from multiple waves. Other such complex scenarios include adaptive and responsive designs, which were developed to act on the results of such monitoring to implement prespecified options or alternatives in protocols. This paper discusses the development of an interactive web-based data visualization tool, the Adaptive Total Design (ATD) Dashboard, which we designed to provide a wide array of survey staff with the information needed to monitor data collection daily. The dashboard was built using the R programming language and Shiny framework and provides users with a wide range of functionality to quickly assess trends. We present the structure of the data used to populate the dashboard, its design, and the process for hosting it on the web. Furthermore, we provide guidance on graphic design, data taxonomy, and software decisions that can help guide others in the process of developing their own data collection monitoring systems. To illustrate the benefits of the dashboard, we present examples from the National Longitudinal Study of Adolescent to Adult Health (Add Health). We also discuss features of the dashboard to be developed for future waves of Add Health.

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