Academic literature on the topic 'Sublingual Drug'

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Journal articles on the topic "Sublingual Drug"

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Gadekar, Nilesh Shivaji, Sakshi Machhindra Gaikwad, and Swati Bhagwan Katkar. "Review on Sublingual Tablet." International Journal for Research in Applied Science and Engineering Technology 12, no. 1 (2024): 1358–63. http://dx.doi.org/10.22214/ijraset.2024.58175.

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Abstract: Objective: As sublingually given dose forms avoid hepatic metabolism, sublingual medication delivery can be an alternate and superior method to oral drug delivery. For some medications, particularly those prescribed for the treatment of acute diseases, a quick onset of pharmacological activity is frequently required. Sublingual pills dissolve quickly, and the major saliva available is typically enough to achieve dosage form disintegration along with enhanced dissolving and increased bioavailability. Findings: Comparing sublingual pills to traditional dosage forms, it was discovered t
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Saha, Puja, Sushma Verma, and Pratik Swarup Das. "SUBLINGUAL DRUG DELIVERY: AN INDICATION OF POTENTIAL ALTERNATIVE ROUTE." International Journal of Current Pharmaceutical Research 9, no. 6 (2017): 5. http://dx.doi.org/10.22159/ijcpr.2017v9i6.23436.

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Sublingual literally meaning is “under the tongue”, refers to a method of administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. Sublingual route is a useful when rapid onset of action is desired with better patient compliance than orally ingested tablets. Drugs that are given sublingually reach directly in to the systemic circulation through the ventral surface of the tongue and floor of the mouth. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving accepta
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Ashok, Kumar Sharma, Pushpendra Singh Naruka Dr., Shankar Soni Mr., Mohit Khandelwal Mr., Shaneza Aman Ms., and Mehul Mr. "SUBLINGUAL TABLET- ADVANCEMENT IN TABLET DOSAGES FORM." International Journal of Current Pharmaceutical Review and Research 11, no. 2 (2019): 01–05. https://doi.org/10.5281/zenodo.12672960.

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Sublingual drug delivery is often an alternate and better choice of route in comparison to oraldrug delivery as sublingually administered dosage forms bypass hepatic metabolism. A rapidonset of pharmacological effect is usually desired for a few drugs, especially those utilizedin the treatment of acute disorders and need onset of action. Sublingual tablets disintegraterapidly and therefore the bit of saliva present is typically sufficient for achievingdisintegration of the dosage form including better dissolution and increased bioavailabilitywith effective therapeutic range. Sublingual tablets
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Pawar, Poonam P., Hemant S. Ghorpade, and Bhavana A. Kokane. "Sublingual route for systemic drug delivery." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 340–43. http://dx.doi.org/10.22270/jddt.v8i6-s.2097.

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Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual literally meaning is “under the tongue”, administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in geriatric, pedi
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Aravindhanthan V, Anjali P B, and Arun Radhakrishnan. "Sublingual spray: a new technology oriented formulation with multiple benefits." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 2875–85. http://dx.doi.org/10.26452/ijrps.v10i4.1567.

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Sublingual drug delivery system was a well-established platform for delivering the drug that need to exhibit quick action without any first-pass metabolic effect, but various pitfall in the regular sublingual drug delivery systems such as a tablet, capsule etc., that can be overcome by novel sublingual drug delivery technology such as particulate sublingual spray. Sublingual spray for drug administration has gained attention in the market since it proved its propensity to by-pass the first-pass metabolism and to initiate a rapid onset of action due to its atomized micro particulate nature, whi
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Labhade, Sanjana, Chaitali Malode, Vaishali Rawal, and Smita Rupvate. "Review on Sublingual Drug Delivery System." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 684–88. http://dx.doi.org/10.22270/jddt.v9i3.2684.

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Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a useful when rapid onset of action is desired with better patient compliance than orally administered drugs. In terms of permeability, the sublingual area of the oral cavity is more permeable than the buccal area, which in turn is more permeable than the roof of the mouth area. The portion of drug absorbed through the sublingual blood vessels avoids hepatic first‐pass metabolic processes giving good bioavailability. Sublingual technology for patients need enhanced life
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Het, Patel*, Patel Jaini, Ghanshyam Patel Dr., Yadav Priyanka, and Divykant Patel Dr. "REVIEW-SUBLINGUAL ROUTE FOR SYSTEMIC DRUG DELIVERY." World Journal of Pharmaceutical Science and Research 2, no. 2 (2023): 45–57. https://doi.org/10.5281/zenodo.10894235.

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Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual literally meaning is “under the tongue”, administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in ger
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Himanshi, Rathaur* and G.Gnanarajan. "REVIEW ON: SUBLINGUAL ROUTE FOR SYSTEMIC DRUG DELIVERY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 453–62. https://doi.org/10.5281/zenodo.1161209.

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Delivery of drug in the oral cavity through the oral mucosa is examined to be a promising alternative to the oral route. Sublingual means “under the tongue” which rapidly absorb the drug through the oral mucosa and enter into the systemic circulation. This route provides various advantages such as quick onset of action, patient compliance, hepatic first pass metabolism and increase bioavailability. Dysphagia is a common problem in pediatric, geriatric and psychiatric patients. In terms of permeability sublingual area of oral cavity is more permeable than buccal area which is in tur
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Goswami, Tarun, Bhaskara R. Jasti, and Xiaoling Li. "Sublingual Drug Delivery." Critical Reviews™ in Therapeutic Drug Carrier Systems 25, no. 5 (2008): 449–84. http://dx.doi.org/10.1615/critrevtherdrugcarriersyst.v25.i5.20.

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Kumar, Damit, Amit Sharma, and Rajiv Garg. "FORMULATION AND EVALUATION OF SUBLINGUAL TABLET OF LOSARTAN POTASSIUM." Asian Journal of Pharmaceutical Research and Development 6, no. 4 (2018): 54–66. http://dx.doi.org/10.22270/ajprd.v6i4.386.

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The objective of the current study was to develop and optimize a sublingual tablet of Losartan potassium, which is an effective drug in the treatment of hypertension. Owing to number of advantages dissociated with the quick onset of action and it by passes the liver. Sublingual tablets offer effective and easier way for management of Hypertension. The basic approach used in development of Sublingual tablet was the use of super disintegrants by direct compression method. Oral mucosal drug delivery is one of the promising method of systemic drug delivery which offers several advantages. The lite
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Dissertations / Theses on the topic "Sublingual Drug"

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Kaur, Navdeep. "Sublingual drug delivery: In vitro-in vivo correlation." Scholarly Commons, 2013. https://scholarlycommons.pacific.edu/uop_etds/148.

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Administration of drugs sublingually allows direct absorption into the systemic circulation which results in quick onset of action and a higher bioavailability as a consequence of by-passing first pass metabolism. Absorption of drugs across sublingual mucosa is typically determined by means of in vitro permeation studies using excised sublingual tissue during early phases of drug development. Although in vitro set up has been designed to mimic in vivo system yet the results of in vitro studies often deviate from in vivo results. Therefore, it is not known if the in vitro studies can be used as
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Goswami, Tarun. "Sublingual drug delivery: In vitro characterization of barrier properties and prediction of permeability." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/2370.

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Sublingual administration of drugs offers advantages including avoidance of first pass metabolism and quick absorption into the systemic circulation. In spite of being one of the oldest routes of drug delivery, there is dearth of literature on characterization of the barrier properties of the sublingual mucosa. Therefore, the aim of this research was to gain an insight into the barrier properties of the porcine sublingual mucosa. The studies conducted in this dissertation research focused on an important aspect of sublingual permeation, the dependence of permeability on different physicochemic
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Goswani, Tarun. "Sublingual drug delivery : in vitro characterization of barrier properties and prediction of permeability." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/708.

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Bredenberg, Susanne. "New Concepts in Administration of Drugs in Tablet Form : Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System." Doctoral thesis, Uppsala University, Department of Pharmacy, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3433.

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<p>This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.</p><p>Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. By studying the relationship between disintegration time and tensile strength, it was found that the microstructure surrounding the disintegrant particles may influence the disintegration process. Therefore, avoidance of excipients which are highl
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Chou, Po-Yu, and 周柏宇. "Development of Sildenafil for Rapid-Onset Sublingual Drug Delivery System." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/41302586487992477295.

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碩士<br>臺北醫學大學<br>藥學研究所<br>98<br>Oral sildenafil (Viagra®) is the most popular drug to treat erectile dysfunction. However, it should be taken 1 hour before sexual intercourse and lower bioavailability. It is well known that sublingual delivery of drugs offers rapid absorption and high bioavailability, with subsequent almost immediate onset of pharmacological effect. Due to these superiorities, we developed sildenafil sublingual spray and tablet. Sildenafil in oleic acid, propylene glycol and microemulsion prepared by water phase (H2O), oil phase (oleic acid), surfactant (Tween 80) and cosurfa
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"Development, validation and application of HO-1-u-1 cell line for sublingual drug absorption screening." Thesis, 2005. http://library.cuhk.edu.hk/record=b6075021.

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Finally, the pharmacodynamic effects of propranolol powder formulation with different buffering were carried out in two healthy male subjects. The maximal reduction in heart rate was found at the saliva pH of 7.6, which corresponded to the pHmax of propranolol. A buffered propranolol sublingual tablet was then prepared to achieve the saliva pH around 7.6. The preliminary investigation confirmed that the sublingually administrated buffered propranolol tablet produced a faster and more pronounced heart rate reduction than the non-buffered commercial propranolol tablet.<br>Firstly, the use of the
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Vlková, Veronika. "Hydrofobně laminované nanomembrány." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-324121.

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1 ABSTRACT The diploma thesis first describes the theory biopharmaceutical classification system, it gives a detailed summary of naproxen as the drug used at further in vitro experiments for drug delivery and a brief information about nanofiber membranes in general and their use as drug carriers is also given. Experimental section is focused to in vitro release of naproxen from electrospinning nanofiber membranes with regard to the possibility of the use of lamination. At non-laminated nanofiber membranes with three different concentrations of naproxen (5%, 15% and 30% by weight) the rates of
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Book chapters on the topic "Sublingual Drug"

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Staner, Luc. "Zolpidem Sublingual Formulations." In Drug Treatment of Sleep Disorders. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-11514-6_7.

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Ahmed, Tarek A., and Khalid M. El-Say. "Sublingual Route of Drug Delivery." In The ADME Encyclopedia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84860-6_95.

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Patel, Viralkumar F., Darragh Murnane, and Marc B. Brown. "Buccal/Sublingual Drug Delivery for the Paediatric Population." In Pediatric Formulations. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4899-8011-3_15.

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Rogerson, Alan. "Experimental Models for Buccal and Sublingual Drug Absorption Including Epithelial Cell Multilayers and Monolayers." In Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4757-0286-6_21.

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"Nitroglycerin (sublingual)." In PharmacotherapyFirst Drug Information. The American Pharmacists Association, 2017. http://dx.doi.org/10.21019/druginformation.nitroglycerin_sublingual.

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"Nitroglycerin (sublingual)." In PharmacotherapyFirst Drug Information. The American Pharmacists Association, 2017. http://dx.doi.org/10.21019/pfdi.nitroglycerin.

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"Buccal and Sublingual Drug Delivery." In Drug Delivery. CRC Press, 2016. http://dx.doi.org/10.1201/9781315382579-9.

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"Buccal and sublingual drug delivery systems." In Drug Delivery. Elsevier, 2025. https://doi.org/10.1016/b978-0-443-26787-1.00015-1.

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Davies, Andrew. "Oral transmucosal opioids." In Cancer-related Breakthrough Pain. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198840480.003.0006.

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The oral transmucosal routes are buccal and sublingual. The absorption of drugs across the oral mucosa involves a process of passive absorption, and may involve either the transcellular route or the paracellular route. A number of drug factors affect the absorption of drugs across the oral mucosa. Oral transmucosal drug delivery does not require expertise, preparation, or technical equipment. Oral transmucosal administration may be associated with rapid onset of analgesia. A number of fentanyl-based formulations are commercially available to manage breakthrough cancer pain. A variety of other
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Lamey, P. J., and M. A. O. Lewis. "Buccal and sublingual delivery of drugs." In Routes of Drug Administration. Elsevier, 1990. http://dx.doi.org/10.1016/b978-0-7236-0922-3.50007-9.

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Conference papers on the topic "Sublingual Drug"

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Spinella, Toni, Sherry Stewart, Julia Naugler, Igor Yakovenko, and Sean Barrett. "The power of placebo: Does cannabidiol (CBD) expectancy alone impact acute stress and anxiety?" In 2022 Annual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2022. http://dx.doi.org/10.26828/cannabis.2022.02.000.01.

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Background. There have been notable increases in the use of cannabidiol (CBD) for therapeutic purposes, such as in the treatment of stress- and anxiety- related disorders. Preliminary research has demonstrated that CBD decreases indices of stress and anxiety. However, drug effects in humans are thought to be comprised of both pharmacological properties as well as a placebo response. Little is known about the extent to which the purported therapeutic effects of CBD result from pharmacological versus expectancy factors. Aims. The aim of this study was to evaluate whether (i) CBD expectancy alone
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Reports on the topic "Sublingual Drug"

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Yu, Winifred, Courtney Luterbach, Elise Digga, et al. Association Between Outcomes and Dental Services in People With Substance Use Disorder: A Rapid Response Review. AHRQ, 2025. https://doi.org/10.23970/ahrqepc_rapid_dental_substance.

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This review is undertaken to answer the following questions: Key Question 1: What is the effectiveness of dental services in improving health outcomes in people with substance use disorder (SUD) before, during, or after SUD pharmacologic treatment, including but not limited to transmucosal (sublingual/buccal) buprenorphine and psychotropic drugs? Key Question 2: What are the clinical practice guidelines or standards for dental care for people with SUD? Key Messages: The body of evidence on the effectiveness of dental services in improving health outcomes in people with SUD before, during, or a
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