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Journal articles on the topic 'Submental nodes'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Manohar, Babu, and Raees Abdurahiman. "Thyroglossal duct papillary carcinoma presenting as submental neck node." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 6 (2019): 1745. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20194965.

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<p class="abstract">Neck node in sub mental area is not uncommon. It occurs mostly due to infective or malignant pathologies in oral cavity. Submental neck node mass due to thyroglossal duct cyst carcinoma is a rare presentation. A 25 year old female presented with a sub mental neck node which was noticed for 6 weeks with no history of fever or any oral lesions. On examination, there was a 1 × 1 cm non tender, firm, mobile sub mental neck node. Fine Needle aspiration cytology (FNAC) of the submental node showed features of metastatic papillary carcinoma from thyroid. Whole body Technitiu

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2

Okumuş, Özlem, Merve Dönmez, and Filiz N. Pekiner. "Ultrasonographic Appearances of Cervical Lymph Nodes in Healthy Turkish Adults Subpopulation: Preliminary Study." Open Dentistry Journal 11, no. 1 (2017): 404–12. http://dx.doi.org/10.2174/1874210601711010404.

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Objectives: The aim of the study was to assess whether there was any relation between age, gender and body mass index (BMI) and nodal forms and vascular type in healthy Turkish adults. Study Design: Three neck areas in 25 wholesome patients who were aged from 21 to 58 years, were assessed by gray-scale and color doppler ultrasonography. Ultrasonographic examinations were performed using an ALOKA Prosound Alpha 6 (Hitachi Aloka Medical Systems, Tokyo, Japan) and the images were obtained with a 7.2 MHz linear array transducer. Hajek’s categorization of cervical lymph nodes for sonographic analys

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3

Koç, Can, M. Umut Akyol, Ali Çekiç, Serdar Çelikkanat, and Cafer Özdem. "Role of Suprahyoid Neck Dissection in the Treatment of Squamous Cell Carcinoma of the Lower Lip." Annals of Otology, Rhinology & Laryngology 106, no. 9 (1997): 787–89. http://dx.doi.org/10.1177/000348949710600915.

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Treatment of squamous cell carcinoma of the lip is primarily surgical. Unlike other oral lesions, lower lip cancers do not metastasize to lower cervical lymph nodes without invading submental and submandibular lymph nodes. This study presents 30 patients with NO lower lip carcinoma who were treated by en bloc resection of the tumor with suprahyoid neck dissection. Occult metastasis was found in 4 patients (13%). Four patients, 3 of whom had no occult metastases, died of local or regional uncontrollable disease. Suprahyoid or modified radical neck dissection appears to be beneficial, even in sm

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4

ISHIBASHI, Kenichiro, Humitaka TERASAWA, Mawoomi MOON, Takamasa SHIROZU, Hidenori SAKUMA, and Atsuo KAETSU. "A case of methotrexate-associated Hodgkin's lymphoma of the submental lymph nodes." Japanese Journal of Oral and Maxillofacial Surgery 58, no. 9 (2012): 531–35. http://dx.doi.org/10.5794/jjoms.58.531.

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5

Dr, Kedar Kawsankar, Harish Saluja Dr, Seemit Shah Dr, et al. "Involvement of Submental Lymph Node in Oral Squamous Cell Carcinoma (OSCC)." Involvement of Submental Lymph Node in Oral Squamous Cell Carcinoma (OSCC) 8, no. 10 (2023): 5. https://doi.org/10.5281/zenodo.10099196.

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Background: Squamous cell carcinoma (OSCC) is one of the most common malignancies of oral cavity. Metastasis of oral squamous cell carcinoma (OSCC) is a complex process involving detachment of cells from the tumor tissue, regulation of cell motility and invasion, proliferation and evasion through the lymphatic system or blood vessels. The metastasis may affect the prognosis. 1Since not only the suppression of primary lesion but also the presence or absence of metastasis in the cervical lymph nodes may greatly influence the outcome of oral cancer. 2, 3The submental lymph nodes are categories as

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6

Ferlito, Alfio, and Alessandra Rinaldo. "Level I dissection for laryngeal and hypopharyngeal cancer: is it indicated?" Journal of Laryngology & Otology 112, no. 5 (1998): 438–40. http://dx.doi.org/10.1017/s0022215100140721.

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AbstractSquamous cell carcinoma of the larynx and hypopharynx tends to metastasize frequently to cervical lymph nodes, the location of which depends mainly on the site of the primary lesion. Five anatomical levels of cervical nodes have consequently been defined to standardize the terminology used to describe which lymph node groups are at risk for metastatic spread. Level I includes the submental and submandibular triangles. This review considers the role of these triangles in neck dissection and concludes that, unless there is clear evidence of spread, the inclusion of the level I triangles

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7

Ogassavara, Beatriz, Raul Renato Tucunduva Neto, Romeu Rodrigues de Souza, and Maria José Tucunduva. "Ultrasound evaluation of the morphometric patterns of lymph nodes of the head and neck in young and middle-aged individuals." Radiologia Brasileira 49, no. 4 (2016): 225–28. http://dx.doi.org/10.1590/0100-3984.2015.0002.

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Abstract Objective: To show the morphometric patterns of lymph nodes of the head and neck, evaluating their number, shape, dimensions, hilum, and cortex, through the use of ultrasound examination of the neck. Materials and Methods: We analyzed 400 right and left lymph nodes in a group of 20 healthy young and middle-aged individuals of both genders. Results: In the ultrasound examination, we observed the following lymph nodes: mastoid; parotid (superficial, extraglandular, and intraglandular); submandibular (preglandular, retroglandular, and intracapsular); submental; and cervical (anterior and

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8

Asuncion, Mora-Ortiz, Sung-Yu Chu, Yen-Ling Huang, Chia-Yu Lin, and Ming-Huei Cheng. "Accurate Prediction of Submental Lymph Nodes Using Magnetic Resonance Imaging for Lymphedema Surgery." Plastic and Reconstructive Surgery - Global Open 6, no. 3 (2018): e1691. http://dx.doi.org/10.1097/gox.0000000000001691.

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9

SUYAMA, Kazutaka, Souichi YANAMOTO, Goro KAWASAKI, Michi-ichirou ITOH, Akio MIZUNO, and Shuichi FUJITA. "A case of multiple calcifications in the bilateral submandibular and submental lymph nodes." Japanese Journal of Oral & Maxillofacial Surgery 46, no. 7 (2000): 448–50. http://dx.doi.org/10.5794/jjoms.46.448.

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10

Beederman, Maureen, and David W. Chang. "Supraclavicular lymph node transplant: a focus on technique." Plastic and Aesthetic Research 9, no. 9 (2022): 54. http://dx.doi.org/10.20517/2347-9264.2022.64.

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Physiologic surgical options, including vascularized lymph node transplant and lymphovenous bypass are becoming increasingly popular interventions for the treatment of lymphedema of both the upper and lower extremities. Many different lymph node donor sites have been described, including submental, lateral thoracic, superficial groin, supraclavicular, and various intraabdominal sites. This paper describes a step-by-step approach to the harvest of vascularized lymph nodes from the supraclavicular area, which is the preferred donor site for most patients with both upper and lower extremity lymph

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11

Suzuki, Hidenori, Shintaro Beppu, Daisuke Nishikawa, Hoshino Terada, Michi Sawabe, and Nobuhiro Hanai. "Lymph Node Ratio in Head and Neck Cancer with Submental Flap Reconstruction." Biomedicines 10, no. 11 (2022): 2923. http://dx.doi.org/10.3390/biomedicines10112923.

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This study aimed to investigate the relationship between the lymph node ratio (LNR) and survival results of patients with head and neck squamous cell carcinoma (HNSCC) reconstructed by a submental artery flap (SMAF) to limit tumor size. This study retrospectively recruited 49 patients with HNSCC who underwent both primary resection and neck dissection with SMAF reconstruction. The LNR was the ratio of the number of metastatic lymph nodes to the sum number of examined lymph nodes. A LNR of 0.04 was the best cut-off value for HNSCC-specific death on receiver operating curve analysis. Patients wi

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12

Cechanovičiūtė, Vaiva, and Inga Cechanovičienė. "VASCULARIZED LYMPH NODE TRANSFER FOR TREATMENT OF BREAST CANCER-RELATED LYMPHEDEMA: INDICATIONS, DONOR SITES AND COMPLICATIONS." Health Sciences 34, no. 3 (2024): 171–73. http://dx.doi.org/10.35988/sm-hs.2024.128.

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Breast cancer-related lymphedema (BCRL) is as a burden for patients treated for breast cancer. Despite its main management being focused on conservative methods, moderate or severe cases may be resistant and require surgical treatment. One of the commonly used techniques is vascularized lymph node transfer (VLNT) which allows the relocation of normal lymph nodes to the affected limb to ensure proper lymph flow, thus relieving lymphedema. The donor site is chosen based on the risk of iatrogenic lymphedema and scarring. Despite the inguinal region has a great risk for donor site lymphedema, i

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13

Khan, Abdullah, Riaz Ahmed Warraich, Sadiq Ali, Ashfaq-Ur Rahim, Muhammad Nauman, and Urooj Kirmani. "Reconstruction of Intra-Oral Defects with Submental Artery Flap: A Comparison of pN+ and pN0 Oral Squamous Cell Carcinoma Patients." Pakistan Journal of Medical and Health Sciences 17, no. 9 (2023): 2–5. http://dx.doi.org/10.53350/pjmhs20231792.

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Aim: To compare the reconstruction of intra-oral defects with submental artery flap among pN+ and pN0 oral squamous cell carcinoma patients. Methodology: A comparative analytical prospective study was conducted in the Department of Oral and Maxillofacial Surgery, University of Lahore, from January 1, 2022, to November 1, 2022. Fifty-five confirmed cases of oral squamous cell carcinoma were included. The inclusion criteria were based on oral cavity carcinoma patients presenting for tumour resection and reconstruction of the resultant defects with the submental artery flap. A pinch test was appl

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14

Danforth, Rachel, and Roman Skoracki. "Intra-abdominal donors for vascularized lymph node transfer: an update and review." Plastic and Aesthetic Research 8, no. 8 (2022): 48. http://dx.doi.org/10.20517/2347-9264.2021.34.

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Lymphedema continues to be a very challenging clinical problem. While compression and physical therapy remain the foundation of treatment, recent advances in microsurgery and super-microsurgery have allowed for the development of promising surgical options. One of these options is vascularized lymph node transfer (VLNT), which has gained significant popularity over recent years. However, there is no consensus on the ideal donor lymph node basin for VLNT. In addition, the most commonly reported donor sites, including the groin, supraclavicular, submental, and lateral thoracic nodes, carry the r

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15

Trivic, Aleksandar, S. Krejovic-Trivic, Jovica Milovanovic, et al. "Distribucija cervikalnih metastaza karcinoma cervikofacijalne regije." Acta chirurgica Iugoslavica 51, no. 1 (2004): 83–87. http://dx.doi.org/10.2298/aci0401083t.

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The primary goal in the therapy of patients with cervico-facial cancers has been always the control of loco-regional disease. It is more difficult to control metastasis than primary tumor. According to numerous authors, metastases to cervical lymphonodus reduce the survival of patients with planocellular cancer of the upper aero-digestive pathways for about 50%. Precise classification of primary tumor and regional lymphonodus is highly significant for adequate and timely treatment of patients with cancers of cervico-facial region. The objective of our study was to make clinical classification

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16

Tartaglione, G., C. Potenza, A. Caggiati, et al. "Lymphatic Mapping and Sentinel Node Identification in Squamous Cell Carcinoma and Melanoma of the Head and Neck." Tumori Journal 88, no. 3 (2002): S39—S41. http://dx.doi.org/10.1177/030089160208800337.

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Aim The aim of our study was to evaluate the role of scintigraphy in lymphatic mapping and in the identification of the sentinel lymph node (SLN) in patients with head and neck cancer. Methods Between September 1999 and February 2001 we enrolled 22 consecutive patients with cancer in the head and neck region: five squamous cell carcinomas, one Merkel cell tumor of the cheek, and 16 malignant melanomas. Lymphoscintigraphy was performed three hours before surgery after injection of 30-50 MBq of 99mTc-Nanocoll in 0.3 mL; the dose was fractionated by injecting the radiotracer at two points around

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17

Roy, Asitava Deb, Shruti Singh, Mala, and Amitabh Anand. "Angiomyomatous hamartoma: Unusual presentation of a rare entity." IP Archives of Cytology and Histopathology Research 9, no. 2 (2024): 114–16. http://dx.doi.org/10.18231/j.achr.2024.023.

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Angiomyomatous hamartoma (AMH) is a rare benign vascular growth primarily affecting inguinal and femoral lymph nodes (LNs). Here, we present a unique case of AMH manifesting as a submental neck mass, a location seldom reported in literature. A 20-year-old male presented with a palpable midline neck mass adjacent to the hyoid bone. Ultrasonography suggested a partially cystic lesion, prompting consideration of thyroglossal duct cyst or necrotic lymph node. Fine-needle aspiration (FNA) hinted at a benign cystic lesion, potentially a thyroglossal duct cyst. Surgical excision via the Sistrunk appr

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18

Behranwala, Ruqaiyah, Bhagya Harindi Loku Waduge, and Bervin Teo. "Nasal mucosal melanoma as a cause of epistaxis." BMJ Case Reports 12, no. 7 (2019): e228640. http://dx.doi.org/10.1136/bcr-2018-228640.

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A 43-year-old woman presented with an 8-week history of fatigue and recurrent right sided nasal bleeds progressing to significant pain and swelling on the right side of her face. Clinical examination revealed a friable mass in her right nasal passage. A biopsy and staging positron emission tomography-CT scan confirmed the diagnosis of a T4 N1 M1 BRAF wild type mucosal melanoma. The melanoma had metastasised to the right paranasal sinuses, right and left neck nodes, right submental node, right upper breast, liver, the subcutaneous fat of the left buttock and the right iliac bone as well as cere

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Schnur, Jack, Mary E. Johnson Shaw, Lorenzo R. Carnio, and Damian Casadesus. "Aggressive squamous cell carcinoma of the lip." BMJ Case Reports 13, no. 12 (2020): e239281. http://dx.doi.org/10.1136/bcr-2020-239281.

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Squamous cell carcinoma (SCC) of the lip typically has a good prognosis when diagnosed at an early stage and treated properly. We present a 65-year-old man with a 3-month history of an ulcerative lesion of the lower lip. On physical examination, he had an ulceration of approximately 5×5 cm in the mucosa of the lower lip, extending through 50% of the lip, and multiple mandibular and neck lymph nodes. The biopsy confirmed SCC of the lip. Surgical treatment was recommended, but the patient was lost to follow-up. The patient eventually returned to the hospital for medical treatment. However, the p

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Ghosh, Debadrita, Arvind Kumar, Chitrita G. Mukherjee, and Navin K. Verma. "Unilateral mandibular central giant cell granuloma in a child: a case report." International Journal of Research in Medical Sciences 13, no. 7 (2025): 3030–33. https://doi.org/10.18203/2320-6012.ijrms20252044.

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At the Department of Pedodontics of Buddha Institute of Dental Sciences and Hospital (BIDSH), an 11-year-old girl presented with a main complaint of widespread edema measuring 2×3 cm along her left cheek. It was really hard and not at all sensitive. "The lymph nodes in the left submental region and the submandibular region were soft, sensitive, movable, and palpable. Located in the lower left vestibule, an intra-oral growth measuring approximately 4 into 4 cm was observed. A destructive lesion stretching from the lower canine region on the right side to the lower central incisor on the left wa

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Gustafsson, Jonas, Sung-Yu Chu, Wen-Hui Chan, and Ming-Huei Cheng. "Correlation between Quantity of Transferred Lymph Nodes and Outcome in Vascularized Submental Lymph Node Flap Transfer for Lower Limb Lymphedema." Plastic and Reconstructive Surgery 142, no. 4 (2018): 1056–63. http://dx.doi.org/10.1097/prs.0000000000004793.

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22

Paka Lubamba, Grace, Peng Kun Xu, Jian Guan, et al. "Keratinizing Squamous Cell Carcinoma of the Palate in Clinically Negative Neck: Case Report and Review." International Journal of Medical Science and Clinical Invention 8, no. 02 (2021): 5223–31. http://dx.doi.org/10.18535/ijmsci/v8i02.02.

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Background: The Squamous cell carcinoma of the palate is rare; women are more affected than men. This study aimed to discuss the etiology, diagnostic modalities, prognosis factors, and treatment strategies. Case: A 49-year-old woman was admitted to our department in 2019 with a chief complaint of a hard and painful mass on the right palate. The Clinical assessment revealed a palatal tumor extended to 3/4 of hard palate and part of the soft palate, with hard consistency, no mobility, cauliflower-like surface partly covered by a white pseudo-membrane, dark red-colored, and clinically negat

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Zam, Syarifah Nova Amiza, Fuad Fatkhurrohman -, Briliana Ikrimazahra, Dea Hardyana Putri, Nabela Intania Sekarini, and Khairunnisa Pulungan. "Penatalaksanaan Abses Submandibula Sinistra Et Causa Gangren Radix Pada Pasien Hepatitis Di RSUD Sultan Fatah Demak." Cakradonya Dental Journal 16, no. 1 (2024): 24–29. http://dx.doi.org/10.24815/cdj.v16i1.32194.

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Submandibula abscess is a mixture of pus that collects in one area in a network, namely the submandibula area caused by bacterial infection, parasites, or other foreign bodies. The cause of submandibula infection generally originates from the mandibular first and second molar teeth from the spread of infection from the sublingual and submental spaces. Symptoms of a submandibula abscess are characterized by pain and swelling of the cheeks to the inner neck where infection occurs. Infection that occurs in the submandibula space originates from infection of the floor of the mouth, teeth, pharynx,

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Chambers, A. J., T. Murynka, J. P. Arlette, and J. G. Mckinnon. "Invasive melanoma of the face: Patterns of local and regional disease in 261 patients managed at a single institution." Journal of Clinical Oncology 27, no. 15_suppl (2009): e20015-e20015. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e20015.

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e20015 Background: The face is a common site of melanoma occurrence, and lesions in this location present specific management challenges. The purpose of this study was to examine outcomes associated with invasive melanoma of the face, with respect to local, regional and distant recurrence. Methods: Patients with invasive melanoma of the face managed from 1997–2008 were identified from a large population-based tumor registry and retrospectively reviewed. Details of lesion histopathology, initial management, sentinel node biopsy (SNB), and local, regional or distant recurrences were recorded. Re

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S, Sahriany, Agus Alim Abdulah, and Mansyur Arif. "LEUKEMIC PHASE OF MALIGNANT LYMPHOMA IN CHILDREN." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 25, no. 1 (2018): 121. http://dx.doi.org/10.24293/ijcpml.v25i1.1519.

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Leukemic phase of malignant lymphoma is a group of lymphoid malignancies typically localized in lymph node and present typical clinical features such as lymphadenopathy with irregular distribution. It can manifest as an extranodal disorder infiltrates the bloodstream (leukemic phase). Lymphomas are differentiated into Hodgkin and non-Hodgkin. The presentation of Reed-Sternberg (RS) cells in histological evaluation establishes Hodgkin lymphoma. A number of classification systems have been used before the publication of Revised European American Lymphoma (REAL) classification in 1994 which inclu

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Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "An Essential Parameters of Anatomy of Lymph Node Include Structure, Functions, Embryology, Blood Supply, Different Types of Lymph Nodes and Clinical Significance." Journal of Research and Reviews in Homeopathy, Siddha & Unani 2, no. 1 (2025): 38–47. https://doi.org/10.5281/zenodo.15516610.

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<em>Lymphatic vessels and lymphoid organs, including the tonsils, spleen, lymph nodes, and thymus, make up the lymphatic system. These aid in cell recycling at the end of its life cycle, interstitial fluid filtration and drainage, and acquired and innate immunity. End-stage capillary fluid leakage is returned to the vascular system through the superficial and deep lymphatic vessels, which empty into the thoracic duct and the right lymphatic duct. The lymph from the right upper quadrant of the body is drained by the right lymphatic duct, which passes along the medial edge of the scalenus anteri

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Saha, Aditi Subrata, Anoop A, Sandeep Vijay, Raveena Nair, Linu Thomas, and Rithin George. "Oncological safety of harvesting local flaps from the neck in clinically node positive patients with oral squamous cell carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e18065-e18065. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e18065.

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e18065 Background: Reconstruction of complex orofacial defects following tumour resection has always posed as a challenge for clinicians for providing functional and morphological outcomes. Though microvascular free flaps revolutionized reconstruction, local flaps provide a viable alternative in resource constraint settings. Oncological safety of harvesting local flaps has always been a matter of debate in oral squamous cell carcinoma due to proximity of nodal stations. Available literature on oncological safety is limited to clinically node negative patients. The purpose of this study was to

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Saha, Aditi Subrata, Anoop A, Sandeep Vijay, Raveena Nair, Linu Thomas, and Rithin George. "Oncological safety of harvesting local flaps from the neck in clinically node positive patients with oral squamous cell carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e18065-e18065. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e18065.

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e18065 Background: Reconstruction of complex orofacial defects following tumour resection has always posed as a challenge for clinicians for providing functional and morphological outcomes. Though microvascular free flaps revolutionized reconstruction, local flaps provide a viable alternative in resource constraint settings. Oncological safety of harvesting local flaps has always been a matter of debate in oral squamous cell carcinoma due to proximity of nodal stations. Available literature on oncological safety is limited to clinically node negative patients. The purpose of this study was to

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Yahya Salim ,, Siamand, and Wesam Amjad Boya Kaka. "Management Outcomes of Lymphadenopathy among the Children." Diyala Journal of Medicine 25, no. 2 (2023): 111–21. http://dx.doi.org/10.26505/djm.v25i2.1055.

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Background: Lymphadenopathy refers to the enlargement of lymph nodes due to various causes, and its appropriate management is crucial for optimal patient outcomes. Objective: To analyze the onset of lymphadenopathy (LAP) in children in terms of gender and age, explore its clinical manifestations and the specific lymph node areas affected, identify prevalent causes, and assess the outcomes of various treatment approaches. Patients and Methods: This cross-sectional study conducted between October 2021 and March 2023 at Rapareen Teaching Hospital for Children in Erbil City, which exam

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Agrawal, Ranjan, Prateek Sharma, and Imran Khan. "Spectrum of Cervical Lymphadenopathy on Cytopathology in Western Uttar Pradesh." Journal of Medical Sciences and Health 10, no. 3 (2025): 315–19. https://doi.org/10.46347/jmsh.v10.i3.24.191.

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Introduction: In the Indian population cervical lymphadenopathy is prevalent and poses a diagnostic challenge for the diagnostician as well as the treating clinicians. The prevalence of lymphadenopathy affecting the cervical area have been reported to range from 79-89% of all lymphadenopathies. The commonest site affected is the cervical region followed by axillary, occipital, supraclavicular, submental and inguinal lymph nodes. Aetiologies leading to cervical lymphadenopathy range in seriousness from infective cause to malignant pathology. The study was aimed to analyse the diverse clinical m

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Brohl, Andrew S., and Vernon K. Sondak. "Neoadjuvant Checkpoint Inhibitor Therapy for Merkel Cell Carcinoma." Journal of Clinical Oncology 38, no. 22 (2020): 2471–75. http://dx.doi.org/10.1200/jco.20.00752.

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The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors’ suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice. A 78-year-old man presented with rapidly enlarging lymph nodes in the right preau

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Ndèye Fatou Kane Ba, Kanta Ka, El Hadji Aliou Baldé, et al. "Temporo-frontal and parotidial hidradenocarcinoma: A case report." World Journal of Advanced Research and Reviews 19, no. 2 (2023): 1325–29. http://dx.doi.org/10.30574/wjarr.2023.19.2.1718.

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Introduction: Hidradenocarcinoma is a very rare malignant tumor of the sweat glands. Diagnosis is based essentially on histological and immunohistochemical studies. Standard treatment is surgery combined with radiotherapy if there is a prognostic factor for local recurrence. We report a case treated in our department. Observation: A 24-year-old female patient with no specific pathological history consulted the Joliot Curie Institute of the Dantec Hospital for a forehead nodule that appeared in 2012 and was painless, evolving towards February 2021 into two right temporo-maxillary masses progres

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Yahya Salim, Siamand, and Wesam Amjad Boya Kaka. "Management Outcomes of Lymphadenopathy among the Children." Diyala Journal of Medicine 25, no. 2 (2023): 111–21. http://dx.doi.org/10.26505/djm.25027640613.

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Background: Lymphadenopathy refers to the enlargement of lymph nodes due to various causes, and its appropriate management is crucial for optimal patient outcomes. Objective: To analyze the onset of lymphadenopathy (LAP) in children in terms of gender and age, explore its clinical manifestations and the specific lymph node areas affected, identify prevalent causes, and assess the outcomes of various treatment approaches. Patients and Methods: This cross-sectional study conducted between October 2021 and March 2023 at Rapareen Teaching Hospital for Children in Erbil City, which examined the lym

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Ndèye, Fatou Kane Ba, Ka Kanta, Hadji Aliou Baldé El, et al. "Temporo-frontal and parotidial hidradenocarcinoma: A case report." World Journal of Advanced Research and Reviews 19, no. 2 (2023): 1325–29. https://doi.org/10.5281/zenodo.10852491.

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<strong>Introduction</strong>: Hidradenocarcinoma is a very rare malignant tumor of the sweat glands. Diagnosis is based essentially on histological and immunohistochemical studies. Standard treatment is surgery combined with radiotherapy if there is a prognostic factor for local recurrence. We report a case treated in our department. <strong>Observation:</strong> A 24-year-old female patient with no specific pathological history consulted the Joliot Curie Institute of the Dantec Hospital for a forehead nodule that appeared in 2012 and was painless, evolving towards February 2021 into two

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Hui, Thomas Chin Wai, Lik Hang Lam, Weimin Li, Kai Cheung Chow, and Shui On Leung. "513 - Blockage of IL-25 pathway as a potential target therapy for atopic dermatitis." British Journal of Dermatology 190, Supplement_2 (2024): ii17. http://dx.doi.org/10.1093/bjd/ljad498.020.

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Abstract Introduction Interleukin 25 (IL-25) is an alarmin that binds to its receptor composed of IL-17RA and IL-17RB and is known to induce the production of type 2 cytokines, leading to T helper type 2 (Th2) inflammatory responses. Atopic dermatitis (AD) is an autoimmune and chronic disorder that causes inflammation, dryness, redness and irritation of the skin. It is well-documented that upregulated IL-25 expression is tightly correlated with the disease severity of AD patients, suggesting that the IL-25 pathway is a potential therapeutic target of AD. SM17 is a humanized antibody of the Ig

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Oommen, Sneha Ann, Bharat Umakant Patil, Pravinkumar Ghongade, and Nitin Gangane. "Cartridge-Based Nucleic Acid Amplification Test Compared to Fine Needle Aspiration Cytology in Suspected Cases of Tubercular Lymphadenitis (the Indian Experience)." I.P. Pavlov Russian Medical Biological Herald 32, no. 3 (2024): 425–32. http://dx.doi.org/10.17816/pavlovj321580.

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INTRODUCTION: Diagnosis of tubercular lymphadenitis is daunting as there are varied clinical presentations and no single confirmatory gold standard test. Cartridge-based nucleic acid amplification test (CBNAAT) of the lymph node is a rapid molecular diagnostic test for simultaneously detecting tuberculosis (TB) and rifampicin resistance. AIM: To evaluate the performance of the CBNAAT test for detecting M. tuberculosis in lymph node specimens compared to fine needle aspiration cytology (FNAC). MATERIALS AND METHODS: The study was conducted in a rural tertiary care hospital in central India. A t

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Kangloo, Shubhanshi, Nitin Bhola, Anchal Agarwal, Raj Kumar Chakraborty, Priyatam Mishra, and Saurabh Pillai. "Reconstruction of Partial Glossectomy Defects in Patients with Squamous Cell Carcinoma of Oral Tongue: A Prospective Clinical Study on the Assessment and Comparison of Intraoperative and Postoperative Outcomes of Islanded Nasolabial Flap Tunneled Under the Mandible and Radial Forearm Free Flap." Journal of Head & Neck Physicians and Surgeons 11, no. 2 (2023): 114–20. http://dx.doi.org/10.4103/jhnps.jhnps_12_23.

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Background: Reconstruction of the glossectomy defect following surgery plays a pivotal role in a patient’s quality of life. Reconstruction of surgical defects following glossectomy has evolved greatly from locoregional flaps such as nasolabial, submental, infrahyoid, and pectoralis major myocutaneous flaps to microvascular free flaps (radial forearm free flap [RAFF], anterolateral thigh flap). Due to certain drawbacks, microvascular-free flaps are avoided; instead, local/regional flaps are preferred. Islanded Nasolabial Flap Tunneled Under the Mandible (INFTUM) is a modification of the convent

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Almakadi, Mohammed, Dalal Aldhafeeri, Amine Hameg, and Badr Aljoaid. "Acute Myeloid Leukemia with a Glossal Mass." Blood 144, Supplement 1 (2024): 5986. https://doi.org/10.1182/blood-2024-210757.

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Introduction Acute Myeloid Leukemia (AML) is an aggressive heterogeneous cancer of the bone marrow that stems from the unrestrained expansion of diseased hematopoietic cells coupled with a state of maturation arrest. Accounting for around 10% of cases, AML can manifest with extramedullary (EM) involvement. Common sites include soft tissues, skin, lymph nodes, and rarely the CNS. EM disease can be an additional risk for poor disease outcomes. Case Presentation A 37-year-old male was referred to our center as a case of acute leukemia. He had persistent fever, flu-like symptoms, and cervical lymp

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Pink, Richard, Petr Heinz, Srinivasa R. Chandra, et al. "Are Submental Flap Reconstructions From Oncological and Reconstructive Perspective Safe? Evaluation and Review of Ipsilateral and Contralateral Submental Flap Reconstructions." Journal of Craniofacial Surgery, March 31, 2025. https://doi.org/10.1097/scs.0000000000011240.

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This study compared the risk of nodal metastasis progression in the submandibular area when using submental flap contralateral (SFC) or submental flap ipsilateral (SFI) relative to the tumor side. Thirty patients underwent treatment for squamous cell carcinoma of the oral cavity. Submental flap ipsilateral and SFC were used in 14 and 16 patients, respectively. After unilateral supraomohyoid neck dissection (levels I–III), the SFC group showed a significantly higher total number of positive lymph nodes removed (P = 0.014). In addition, the number of positive lymph nodes in the IB region was sig

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Sittitrai, Pichit, Donyarat Ruenmarkkaew, Chananchida Kumkun, and Chonticha Srivanitchapoom. "A retrospective propensity score-matched analysis of oncological and functional outcomes of submental island flap versus radial forearm free flap for oral cavity cancer reconstruction." BMC Oral Health 24, no. 1 (2024). http://dx.doi.org/10.1186/s12903-024-03955-x.

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Abstract Background This retrospective study aims to compare the oncological and functional outcomes of the submental island flap versus the radial forearm free flap used for oral cavity cancer reconstruction after minimizing differences in baseline characteristics. Methods Propensity scores for each oral cavity cancer patient who underwent surgical resection and immediate reconstruction with a submental island flap or a radial forearm free flap with a flap size ≤ 60 cm2 between October 2008 and December 2021 were generated based on the likelihood of being selected given their baseline charact

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Gandhi, Dr Bipin. "EVALUATION OF PRIMARY EXTRANODAL NON-HODGKIN LYMPHOMA: A RECORD BASE STUDY." International Journal of Medical and Biomedical Studies 3, no. 2 (2019). http://dx.doi.org/10.32553/ijmbs.v3i2.639.

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INTRODUCTION: Lesions in head and neck have always been a diagnostic dilemma for a pathologist and a treating clinician. Being on the exposed part of body, they become cosmetically unacceptable. These include lesions arising from the regional group of lymph nodes. Most commonly lymphadenopathy is a common clinical presentation. The diagnostic probability ranges from infections to developmental abnormalities, from inflammatory to malignant lesions. None the less all the lesions in lymph nodes of the head and neck region cannot be limited to a particular age group and gender. Routine staining pr

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Ari M. Abdullah, Aras J. Qaradakhy, Yadgar A. Saeed, et al. "Kikuchi-Fujimoto Disease Coexistent with Papillary Thyroid Carcinoma: A Report of Two Cases." Barw Medical Journal 3, no. 2 (2025). https://doi.org/10.58742/bmj.v3i2.167.

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Abstract Introduction Kikuchi-Fujimoto Disease (KFD), characterized by histiocytic necrotizing lymphadenitis, is a rare condition of unknown etiology. Diagnosis is dependent on lymph node biopsy. Despite its self-limiting nature, accurate identification is essential to exclude more serious conditions. This paper reports on two cases of KFD coexisting with papillary thyroid carcinoma (PTC). Case presentation Two cases of KFD related to papillary thyroid carcinoma (PTC) are described. In Case 1, a 25-year-old woman experienced submental swelling, fever, and exhaustion. Subsequent tests revealed

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Hindawi, Mahmoud Diaa, Ahmed Hamdy, G. Ali, Ruaa Mustafa Qafesha, et al. "Transoral endoscopic thyroidectomy submental vestibular approach for early-stage papillary thyroid carcinoma: a systematic review and meta-analysis." Langenbeck's Archives of Surgery 409, no. 1 (2024). http://dx.doi.org/10.1007/s00423-024-03377-x.

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Abstract Purpose Our study aimed to compare the effectiveness and complications of the transoral endoscopic thyroidectomy submental vestibular approach (TOETSMVA) versus the transoral endoscopic thyroidectomy vestibular approach (TOETVA) or conventional open thyroidectomy (COT) in patients with early-stage papillary thyroid carcinoma (PTC). Methods We searched online databases up to January 2024. The outcomes were analyzed using RevMan 5.4 and inverse variance. Results Seven studies (two RCTs and five retrospective cohort studies) were included. We established higher significance differences f

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Suami, Hiroo, Katrina Gaitatzis, Helen Mackie, et al. "A New Indocyanine Green Lymphography Protocol for Assessment of Lymphedema in the Head and Neck." Otolaryngology–Head and Neck Surgery, July 14, 2025. https://doi.org/10.1002/ohn.1355.

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AbstractHead and neck cancer and its treatment may result in lymphedema, however, no specific imaging criteria have been assigned to diagnose this condition. This study reports an ICG lymphography protocol for investigating changes in individuals experiencing swelling post‐neck dissection. ICG lymphography was performed in 10 healthy participants and 16 individuals who complained of facial or neck swelling following treatment for head and neck cancer. Four ICG injection sites were proposed to demonstrate 3 lymphatic territories draininig to upper cervical, submandibular, and submental nodes. I

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Chebib, Emilien, Guillaume Rougier, Antoine Dubray‐Vautrin, et al. "Lymph Node Evolution in Eyelid and Orbit Squamous Cell Carcinomas." Laryngoscope, June 21, 2024. http://dx.doi.org/10.1002/lary.31584.

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ObjectivesTo describe a large cohort of eyelid and periorbital SCCs, to compare the location of the tumor and of the pathological lymph nodes, and to analyze the risk factors for lymph node involvement among tumor characteristics.MethodsAll patients managed inside our institution for an eyelid and periorbital SCCs were included. Tumor characteristics, imaging setup, excision margins, lymph node evolution features, local, regional, and distant recurrences rates, and global survival were reported. The risk for lymph node involvement and location of pathological lymph nodes were analyzed through

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Li, Pingdong, Haiyang Li, Shuo Ding, et al. "Clinical Application of Submental Island Flaps in Repair and Reconstruction of Head and Neck Tumors: Retrospective Review of a Single-Center Experience." Ear, Nose & Throat Journal, October 25, 2022, 014556132211366. http://dx.doi.org/10.1177/01455613221136671.

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Background Based on our cadaveric study findings and the clinical practice, the improved submental island flaps (SIF) used on a case series to reconstruct postoperative defects were reviewed and analyzed, to summarize the technical operation of flap cutting and propose the anterograde anatomical technique of point-line-plane alignment. Methods The cadaveric study was carried out first and a case series of about 23 head and neck tumor cases that underwent one-stage SIF repair were reviewed and followed up. The intraoperative anatomy, the technical essentials for vascular pedicle protection and

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Solis Pazmiño, Andrea Paola, Carla Rocha, Luis Figueroa, and Cristhian Garcia. "SAT500 Thyroglossal Duct Cyst Cancer: Diagnosis And Management." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.1973.

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Abstract Disclosure: A.P. Solis Pazmiño: None. C. Rocha: None. L. Figueroa: None. C. Garcia: None. Background: Thyroglossal duct remnants form during the embryologic development of the thyroid gland. In rare cases, with an incidence of about 1%, carcinoma is present within these cysts, most commonly papillary thyroid carcinoma. Sistrunk procedure (SP) is the main treatment and optimal patient management includes multidisciplinary consultation in order to improve survival. However, there is a debate about whether SP is enough if there is a malignancy in the thyroid or if total thyroidectomy sho

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Piyaman, Parkpoom, Krittayot Patchanee, Thanaphorn Oonjitti, Rosarin Ratanalekha, and Nutcha Yodrabum. "Surgical anatomy of vascularized submental lymph node flap: Sharing arterial supply of lymph nodes with the skin and topographic relationship with anterior belly of digastric muscle." Journal of Surgical Oncology, October 22, 2019. http://dx.doi.org/10.1002/jso.25734.

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Pradhan, Rajashree, Abhishek Dutta, Sajeeb Mondal, and Upasana Mukherjee. "Papillary carcinoma arising from de novo ectopic thyroid tissue within thyroglossal duct cyst: A rare case report." Journal of Laboratory Physicians, October 8, 2024, 1–6. http://dx.doi.org/10.25259/jlp_18_2024.

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The most common congenital anomaly of thyroglossal duct is a thyroglossal duct cyst, but carcinoma arising from a thyroglossal duct cyst is a rare phenomenon. Carcinomas involving thyroglossal duct cysts are mostly papillary carcinomas. Definitive diagnosis of carcinomas involving thyroglossal duct cysts is done through surgical excision and subsequent histopathological examination. Most carcinomas arise de novo from ectopic thyroid tissue within thyroglossal duct cysts, but the direct spread of papillary carcinomas arising from the thyroid gland can also present themselves as carcinomas invol

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Tukeni, Kedir Negesso, Merid Lemma Kebede, Elias Ababulgu Abadiko, et al. "Kaposi sarcoma in an HIV-infected patient with high CD4 count: a case report and literature review." Frontiers in Medicine 12 (April 25, 2025). https://doi.org/10.3389/fmed.2025.1496863.

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Kaposi sarcoma is a tumor commonly associated with human herpesvirus 8 (HHV-8) infection and is more prevalent in individuals with immunosuppression, such as those with HIV/AIDS, organ transplant recipients, or other conditions causing immune dysfunction. It typically presents as purple patches or nodules commonly affecting the skin or mucous membrane of the gastrointestinal tract, and can spread to the lymph nodes and lungs. This case report describes an 18-year-old male with vertical HIV infection, managed on a regimen of dolutegravir/lamivudine/tenofovir (DTG/3TC/TDF), and with a recent CD4

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