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1

Sibai, Abla Mehio, Thalia Arawi, Waleed Al Faisal, et al. "Ethics Reporting Practices in Aging Research From the Arab Region." Journal of Applied Gerontology 40, no. 1 (2019): 105–9. http://dx.doi.org/10.1177/0733464819886453.

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Objectives: This study aims to assess the extent of ethics reporting practices in aging research from Arab countries. Methods: A systematic scoping review of research on aging in 22 Arab countries from seven databases (1994-2013) identified 637 publications warranting institutional ethical approval and 612 publications warranting informed consent. We used multivariable regression analysis to examine variations by time, place, and study characteristics. Results: Only 36.6% of articles reported approval from a Research Ethics Committee and 38.7% reported informed consent. Reporting of ethical re
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Orumaa, Madleen, Kaire Innos, Maria Suurna, Liis Salumäe, and Piret Veerus. "Quality Assessment of Cervical Cytology Practices in Estonia From 2007 to 2018." Cancer Control 29 (January 2022): 107327482211417. http://dx.doi.org/10.1177/10732748221141794.

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Background Cervical cancer incidence and mortality in Estonia are among the highest in Europe, although the overall coverage with cervical cytology is high. This indicates potential issues with the quality of collection and/or laboratory evaluation of cervical cytology. Objectives The aim of the retrospective observational study was to assess the quality of cervical cytology specimen collection, evaluation, and reporting using laboratory reports in Estonia. Methods The study included women with a cervical cancer diagnosis in 2017−2018. Cervical cytology and histology reports for these women in
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Uba, Belinda Vernyuy. "Predictors of Adverse Events Following Immunization Reporting amongst Healthcare Workers in Jigawa State, Northern Nigeria, 2022." TEXILA INTERNATIONAL JOURNAL OF PUBLIC HEALTH 11, no. 1 (2023): 154–67. http://dx.doi.org/10.21522/tijph.2013.11.01.art015.

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An adverse event following immunization (AEFI) is any untoward medical occurrence that follows immunization and does not necessarily have a causal relationship with the usage of the vaccine. Reporting of AEFI is suboptimal amongst healthcare workers (HWs). This study aimed to determine predictors of HW’s reporting of AEFI. A descriptive cross-sectional study was conducted among HWs in selected health facilities (HFs) in Jigawa State using an open data kit self-administered questionnaire to collect data on socio-demographic characteristics, training, knowledge, and their practices on AEFI repor
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Weeks, Kate L., Darren C. Henstridge, Agus Salim, Jonathan E. Shaw, Thomas H. Marwick, and Julie R. McMullen. "CORP: Practical tools for improving experimental design and reporting of laboratory studies of cardiovascular physiology and metabolism." American Journal of Physiology-Heart and Circulatory Physiology 317, no. 3 (2019): H627—H639. http://dx.doi.org/10.1152/ajpheart.00327.2019.

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The exercise consisted of: 1) a short survey to acquire baseline data on current practices regarding the conduct of animal studies, 2) a series of presentations for promoting awareness and providing advice and practical tools for improving experimental design, and 3) a follow-up survey 12 mo later to assess whether practices had changed. The surveys were compulsory for responsible investigators ( n = 16; paired data presented). Other investigators named on animal ethics applications were encouraged to participate (2017, total of 36 investigators; 2018, 37 investigators). The major findings to
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Lemay, Jacinthe, Fatemah M. Alsaleh, Lulwa Al-Buresli, Mohammed Al-Mutairi, Eman A. Abahussain, and Tania Bayoud. "Reporting of Adverse Drug Reactions in Primary Care Settings in Kuwait: A Comparative Study of Physicians and Pharmacists." Medical Principles and Practice 27, no. 1 (2018): 30–38. http://dx.doi.org/10.1159/000487236.

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Objective: To investigate and compare knowledge, attitudes, and practices regarding pharmacovigilance (PV) and the reporting of adverse drug reactions (ADR) among physicians and pharmacists in primary care settings. Subjects and Methods: A cross-sectional study was conducted, in which a validated self-administered questionnaire was distributed to 386 physicians and 197 pharmacists in 38 primary care clinics in Kuwait. Categorical variables were described using numbers and percentages. The Pearson χ2 test, Fisher exact test, and Mann-Whitney U test were used as appropriate. p < 0.05 was cons
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Donner, Linsey M., W. Scott Campbell, Elizabeth Lyden, and Trevor C. Van Schooneveld. "Assessment of Rapid-Blood-Culture-Identification Result Interpretation and Antibiotic Prescribing Practices." Journal of Clinical Microbiology 55, no. 5 (2017): 1496–507. http://dx.doi.org/10.1128/jcm.02395-16.

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ABSTRACT Rapid pathogen identification can alter antibiotic prescribing practices if interpreted correctly. Microbiology reporting can be difficult to understand, and new technology has made it more challenging. Nebraska Medicine recently implemented the BioFire FilmArray blood culture identification panel (BCID) coupled with stewardship-based education on interpretation. Physician BCID result interpretation and prescribing were assessed via an electronic survey, with a response rate of 40.8% (156/382 surveys). Seven questions required respondents to interpret BCID results, identify the most l
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Niederstadt, Christina, and Sigrid Droste. "Reporting and presenting information retrieval processes: the need for optimizing common practice in health technology assessment." International Journal of Technology Assessment in Health Care 26, no. 4 (2010): 450–57. http://dx.doi.org/10.1017/s0266462310001066.

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Background: Information retrieval (IR) in health technology assessment (HTA) calls for transparency and reproducibility, but common practice in the documentation and presentation of this process is inadequate in fulfilling this demand.Objectives: Our objective is to promote good IR practice by presenting the conceptualization of retrieval and transcription readable to non-information specialists, and reporting of effectively processed search strategies.Methods: We performed a comprehensive database search (04/2010) to synthesize the current state-of-the-art. We then developed graphical and tab
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Fuller, Walter, Otridah Kapona, Aaron Oladipo Aboderin, et al. "Education and Awareness on Antimicrobial Resistance in the WHO African Region: A Systematic Review." Antibiotics 12, no. 11 (2023): 1613. http://dx.doi.org/10.3390/antibiotics12111613.

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This review documents the status of AMR education and awareness in the WHO African region, as well as specific initiatives by its member states in implementing education and awareness interventions, as a strategic objective of the Global Action Plan on AMR, i.e., improve knowledge and understanding on AMR through effective communication, education, and training. A systematic search was conducted in Google Scholar, PubMed, and African Journals Online Library according to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, for articles published in English. Re
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Zhao, Yuxi, and Lifeng Lin. "Good Statistical Practices for Contemporary Meta-Analysis: Examples Based on a Systematic Review on COVID-19 in Pregnancy." BioMedInformatics 1, no. 2 (2021): 64–76. http://dx.doi.org/10.3390/biomedinformatics1020005.

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Systematic reviews and meta-analyses have been increasingly used to pool research findings from multiple studies in medical sciences. The reliability of the synthesized evidence depends highly on the methodological quality of a systematic review and meta-analysis. In recent years, several tools have been developed to guide the reporting and evidence appraisal of systematic reviews and meta-analyses, and much statistical effort has been paid to improve their methodological quality. Nevertheless, many contemporary meta-analyses continue to employ conventional statistical methods, which may be su
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Jonathan, Kivumbi. "Knowledge, Attitudes, and Practices of Family Planning among Mothers attending Antenatal Care in Rural Uganda: Implications for Maternal Health and Population Growth." IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS 9, no. 1 (2024): 55–62. http://dx.doi.org/10.59298/idosr/jbbaf/24/91.5562.

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Family planning remains a critical aspect of maternal health and population management in Uganda, particularly in rural areas. Despite concerted efforts to increase awareness and accessibility, utilization rates remain suboptimal. This descriptive cross-sectional study aimed to assess the knowledge, attitudes, and practices of family planning among mothers attending antenatal care in Kyotera district, Uganda. A sample of 138 participants completed questionnaires, revealing a nuanced landscape: while overall knowledge of family planning was high (73.9%), a significant minority demonstrated poor
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Mheissen, Samer, Jadbinder Seehra, Haris Khan, and Nikolaos Pandis. "Do sample size calculations in longitudinal orthodontic trials use the advantages of this study design?" Angle Orthodontist 92, no. 3 (2022): 402–8. http://dx.doi.org/10.2319/091321-707.1.

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ABSTRACT Objectives To examine whether optimal calculations of the sample size are being used in longitudinal orthodontic trials. Materials and Methods Longitudinal orthodontic trials with a minimum of three time points of outcome assessment published between January 1, 2017, and December 30, 2020, were sourced from a single electronic database. Study characteristics at the level of each trial were undertaken independently and in duplicate. Descriptive statistics and summary values were calculated. Inferential statistics (Fisher's exact test and logistic regression) were applied to detect asso
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Michael Alurame Eruaga, Tabat Bature, and Esther Oleiye Itua. "Pharmacovigilance in Nigeria: Addressing challenges in ensuring drug safety and monitoring adverse effects." GSC Advanced Research and Reviews 18, no. 3 (2024): 078–82. http://dx.doi.org/10.30574/gscarr.2024.18.3.0093.

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This paper examines the specific challenges faced by Nigeria in implementing pharmacovigilance measures to ensure drug safety and monitor adverse effects. Despite the critical importance of pharmacovigilance in safeguarding public health, Nigeria grapples with several obstacles in its implementation. Through a nuanced exploration of literature and regulatory frameworks, this study sheds light on the unique hurdles encountered in pharmacovigilance practices within the Nigerian context. Challenges in Nigeria's pharmacovigilance landscape include limited awareness and understanding of pharmacovig
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Hines, Stella E., Clayton H. Brown, Marc Oliver, et al. "Cleaning and Disinfection Perceptions and Use Practices Among Elastomeric Respirator Users in Health care." Workplace Health & Safety 68, no. 12 (2020): 572–82. http://dx.doi.org/10.1177/2165079920938618.

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Background: Reusable elastomeric respirator use in health care may represent one solution to address N95 respirator shortages experienced during infectious disease outbreaks, but cleaning and disinfection requirements may limit their utility. Evidence of respirator cleaning and disinfection behaviors and practices by health care workers may inform guidance on reusable respirator use. Methods: Medical system elastomeric respirator users were surveyed about respirator cleaning and disinfection practices and perceptions via an electronic survey. Respondents were subsequently classified based on r
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Bisson, Kassandra R., Jennifer R. Won, Andrea Beharry, et al. "Novel Approach to Proficiency Testing Highlights Key Practice Variations in Cancer Biomarker Delivery." Journal of Molecular Pathology 5, no. 1 (2024): 1–10. http://dx.doi.org/10.3390/jmp5010001.

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Biomarkers are fundamental to modern oncology practice, forming a close link to pathology practice. Pathology results must be accurate, timely, comprehensive, and comprehendible. External proficiency testing is a key tool in maintaining biomarker quality. Here, we demonstrate the feasibility and utility of a novel end-to-end proficiency testing exercise exploring accuracy, turnaround time, and communication. Challenge specimens were made using resected colon cancer tissue, each paired with a fictional clinical vignette, and distributed to participants who were asked to provide all molecular te
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O'Dwyer, Paul, Viveka Guzman, Emma Wallace, and Frank Doyle. "A scoping review protocol of non-verbal communication utilised in peri-interventive dental and medical procedures." HRB Open Research 5 (July 7, 2022): 49. http://dx.doi.org/10.12688/hrbopenres.13373.1.

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Introduction: Dental operative procedures, by their interventive nature, impede the opportunity for peri-intervention verbal communication between patients and clinicians. This can impair trust, consent, and shared decision making with the potential of adversely affecting patient dignity, and potentially resulting in suboptimal clinical outcomes. This scoping review aims to interrogate the literature concerning non-verbal communication methods used in dental and medical practices during peri-interventive procedures, in aiding communication between clinician and patient. We will also ascertain
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Ramautar, Vijanti, Sergio España, and Siamak Farshidi. "Navigating the Complex ESG Accounting Landscape: Engineering a Method Selection Framework." Complex Systems Informatics and Modeling Quarterly, no. 38 (April 30, 2024): 1–26. http://dx.doi.org/10.7250/csimq.2024-38.01.

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Environmental, social, and governance accounting (ESGA) aids organizations in achieving their sustainability goals through continuous improvement. Suitable method selection is crucial to prevent rework, additional expenses, trivial outcomes, and reduced confidence in sustainability practices. The current ESGA method selection process lacks comprehensive consideration of alternatives and criteria, occasionally resulting in suboptimal choices. This work aims to achieve optimal ESGA by engineering a method selection framework. The research approach is based on the design cycle, where engineering
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Boehmer, Kasey R., Kathleen H. Pine, Samantha Whitman, et al. "Do patients with high versus low treatment and illness burden have different needs? A mixed-methods study of patients living on dialysis." PLOS ONE 16, no. 12 (2021): e0260914. http://dx.doi.org/10.1371/journal.pone.0260914.

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Background Approximately 750,000 people in the U.S. live with end-stage kidney disease (ESKD); the majority receive dialysis. Despite the importance of adherence to dialysis, it remains suboptimal, and one contributor may be patients’ insufficient capacity to cope with their treatment and illness burden. However, it is unclear what, if any, differences exist between patients reporting high versus low treatment and illness burden. Methods We sought to understand these differences using a mixed methods, explanatory sequential design. We enrolled adult patients receiving dialysis, including in-ce
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McGovern, Margaret M., Marta Benach, Sylvan Wallenstein, Joe Boone, and Ira M. Lubin. "Personnel Standards and Quality Assurance Practices of Biochemical Genetic Testing Laboratories in the United States." Archives of Pathology & Laboratory Medicine 127, no. 1 (2003): 71–76. http://dx.doi.org/10.5858/2003-127-71-psaqap.

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Abstract Context.—It has been suggested that specific regulation of laboratories performing genetic testing may be needed to ensure standards and quality assurance, and to safeguard the rights of patients with regard to confidentiality and providing informed consent. Previously, a comprehensive analysis of current practices of molecular genetic testing laboratories was conducted, the results of which have assisted in the assessment of the need for regulation and its impact on access to testing. However, a study designed to determine clinical laboratory practices with regard to biochemical gene
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Yilma, Mengistu, Girma Taye, and Workeabeba Abebe. "Magnitude of standard precautions practices among healthcare workers in health facilities of Low and Middle Income Countries: A systematic review and meta-analysis." PLOS ONE 19, no. 4 (2024): e0302282. http://dx.doi.org/10.1371/journal.pone.0302282.

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Background Standard precautions are the minimum standard of infection control to prevent transmission of infectious agents, protect healthcare workers, patients, and visitors regardless of infection status. The consistent implementation of standard precautions is highly effective in reducing transmission of pathogens that cause HAIs. Despite their effectiveness, compliance, resources, patient behavior, and time constraints are some of the challenges that can arise when implementing standard precautions. The main objective of this meta-analysis was to show the pooled prevalence of safe standard
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Carabaza, Ana Moyeda, Mary Murimi, Alemneh Kabeta Daba, and Jessie Vipham. "Factors Associated With Recommended Complementary Feeding Practices Among Children in Sidama and Oromia Regions in Ethiopia." Current Developments in Nutrition 5, Supplement_2 (2021): 164. http://dx.doi.org/10.1093/cdn/nzab035_072.

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Abstract Objectives To determine complementary feeding practices (CFP) among 6-to-23-month-old children and to identify associations between maternal and household characteristics with CFP. Methods Cross-sectional study conducted among rural communities located within the Sidama and Oromia regions in Ethiopia. Pairs of mothers and their children (N = 190) were randomly selected to participate in the survey. Data was collected using the WHO Infant and Young Child Feeding indicators, Household Food Insecurity Access Scale, and Knowledge on CFP. Multivariate logistic regressions were used to anal
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Aybars, Aslı. "The Relationship Between Institutional Investment and Earnings Management." International Journal of Corporate Finance and Accounting 1, no. 1 (2014): 1–21. http://dx.doi.org/10.4018/ijcfa.2014010101.

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The emergence of corporate scandals at the end of the 20th and beginning of the 21th century raised doubts regarding the integrity of financial reporting and the soundness of firms' corporate governance practices. The practice of earnings management is considered to be one of the important causes of these scandals due to its harm to the transparency and quality of financial statements. The discretion exercised by managers in accounting result in agency costs arising from the mismatch between the goals and desires of the principle and the agent causing investors to make suboptimal decisions. Th
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Grimmond, T. "UK safety-engineered device use: changes since the 2013 sharps regulations." Occupational Medicine 69, no. 5 (2019): 352–58. http://dx.doi.org/10.1093/occmed/kqz087.

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Abstract Background The 2013 UK sharps safety regulations require healthcare facilities to use safety-engineered devices (SEDs) to protect staff. The recent increase in UK-reported occupational exposures could indicate increased reporting or increased exposures from suboptimal SED use. Aims To ascertain SED use through examination of sharps container contents in a sample of UK hospitals. Methods Reusable sharps containers (RSCs) were selected from seven UK hospitals in 2013 and seven different hospitals in 2016. At licensed processing facilities, the operator, wearing protective apparel, decan
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Mitchell, Alex J., Isabel Espirito Santo Pereira, Motahare Yadegarfar, Shingai Pepereke, Vongai Mugadza, and Brendon Stubbs. "Breast cancer screening in women with mental illness: comparative meta-analysis of mammography uptake." British Journal of Psychiatry 205, no. 6 (2014): 428–35. http://dx.doi.org/10.1192/bjp.bp.114.147629.

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BackgroundThere is a higher mortality rate due to cancer in people with mental illness and previous work suggests suboptimal medical care in this population. It remains unclear if this extends to breast cancer population screening.AimsTo conduct a systematic review and meta-analysis to establish if women with a mental health condition are less likely to receive mammography screening compared with those without mental ill health.MethodMajor electronic databases were searched from inception until February 2014. We calculated odds ratios (OR) with a random effects meta-analysis comparing mammogra
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Warren, Graham W., Jamie S. Ostroff, Timothy Mullett, et al. "Just ASK: A quality improvement project to enhance smoking assessment and treatment." Journal of Clinical Oncology 41, no. 16_suppl (2023): 6571. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.6571.

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6571 Background: Persistent smoking after cancer diagnosis causes adverse clinical outcomes. ASCO and other organizations view smoking assessment and treatment as indicators of high-quality cancer care. Yet, adoption of clinical practice guidelines like the 3As (Ask, Advise and Assist) for smoking assessment and treatment has been slow and inconsistent in cancer care settings. Methods: Led by the American College of Surgeons Cancer Programs’ Commission on Cancer (CoC) and National Accreditation Program for Breast Centers (NAPBC), the “Just ASK” national quality improvement project focuses on e
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Tran, Dat, Maureen Cassidy, Tara Buehring, and Rebecca Pierce. "1253. Healthcare-Associated Transmission of Burkholderia cepacia Complex Associated With Extrinsically Contaminated Nasal Spray." Open Forum Infectious Diseases 5, suppl_1 (2018): S381—S382. http://dx.doi.org/10.1093/ofid/ofy210.1086.

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Abstract Background Burkholderia cepacia complex (Bcc) species can contaminate medical devices and water-based products, resulting in outbreaks of healthcare-associated infections. In March 2018, we investigated a cluster of 20 patients with a sinus culture positive for Bcc seen at two affiliated ENT clinics in Oregon over a 2-month period, based on reporting by a laboratorian in a central laboratory external to the clinics. Methods We conducted an epidemiologic investigation to identify potential causes for an apparent outbreak of Bcc, including review of health records and microbiologic repo
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Goel, Varun, Dinesh Kumar, Raghavendra Lingaiah, and Sarman Singh. "Occurrence of Needlestick and Injuries among Health-care Workers of a Tertiary Care Teaching Hospital in North India." Journal of Laboratory Physicians 9, no. 01 (2017): 020–25. http://dx.doi.org/10.4103/0974-2727.187917.

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ABSTRACT Introduction: Occupational hazards such as accidental exposure to sharp, cuts, and splashes are common among health-care workers (HCWs). Aims and Objectives: To determine the occurrence of self-reported occupational exposures to these hazards and to know the prevalent practices following the exposure. The second aim was to know the baseline antibody levels against hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) immediately after these accidents. Methods: An observational prospective study was done in the HCWs of a tertiary care academic health
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Logie, Carmen H., Moses Okumu, Isha Berry, et al. "Social contextual factors associated with lifetime HIV testing among the Tushirikiane urban refugee youth cohort in Kampala, Uganda: Cross-sectional findings." International Journal of STD & AIDS 33, no. 4 (2022): 374–84. http://dx.doi.org/10.1177/09564624211069236.

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Background Urban refugee youth may live in social contexts characterized by structural drivers of HIV such as poverty and violence. Knowledge gaps remain regarding HIV testing practices among urban refugee youth, despite the increasing trend toward refugee settlement in urban contexts. This study examined social contextual factors associated with lifetime HIV testing among urban refugee youth in Kampala, Uganda. Methods We conducted a community-based study with a peer-recruited cohort of urban refugee youth aged 16–24 years living in Kampala’s informal settlements, and present baseline cross-s
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Tsangaris, Elena, Rakasa Pattanaik, Joanna O'Gorman, et al. "Outcomes in breast cancer from the patient perspective: Development of an innovative, user-centered platform for collection and reporting of patient-reported data." Journal of Clinical Oncology 39, no. 28_suppl (2021): 188. http://dx.doi.org/10.1200/jco.2020.39.28_suppl.188.

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188 Background: Transition towards a patient-centered healthcare model has been recognized as an important step towards improving the quality and coordination of breast cancer care. Although evidence suggests that patient self-reporting of quality of life improves clinical care, there are significant barriers to successful collection and use of patient-reported data (PRD) including a lack of a technology designed to fully engage patients and providers, limited electronic health record (EHR) integration, and suboptimal clinical implementation strategies. To address this, our team developed imPR
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Malkoff, Nicolas, Brigette Cannata, Dania B. Johnson, Deborah Choe, Maxwell B. Johnson, and Justin Gillenwater. "765 Charting a Path to Enhanced Burn Care: Standardized Note Templates and Resident Perspectives." Journal of Burn Care & Research 45, Supplement_1 (2024): 238. http://dx.doi.org/10.1093/jbcr/irae036.307.

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Abstract Introduction Common Data Elements (CDE) are standardized questions with a set of limited responses that are used systematically across multiple sites. They have been proposed as a means of standardizing clinical documentation and improving interinstitutional data sharing. Our previous work identified 33 CDEs relevant to burn care based on published recommendations and found that they were documented inconsistently in our burn center. Our aim was to assess current charting practices and attitudes toward CDE-focused note templates at our institution as part of a larger effort to standar
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Hessels, Amanda, and Jingwen Guo. "A Large-Scale Snapshot of Standard Precaution Adherence: “Do as I Say Not as I Do”." Infection Control & Hospital Epidemiology 41, S1 (2020): s454—s455. http://dx.doi.org/10.1017/ice.2020.1127.

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Background: Nearly 1 in 25 patients has a hospital infection at any given time, and 1 in 25 nurses suffers and bloodborne exposure every year. Basic procedures, termed standard precautions (SP) may prevent these outcomes, but they are not often used by healthcare workers. Unfortunately, data are largely limited by self-reporting because no standardized tools exist to capture observational data. Objective: The specific aim of this study was to describe the relationship between self-reported and observed SP adherence. Methods: This multisite, cross-sectional study included 2 elements: (1) survey
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Caniza, M., J. Contreras, G. Santana, et al. "#68: Outcomes of Establishing Infection Care and Prevention Standards in Pediatric Oncology Units in Three Hospitals on the Island of Hispaniola." Journal of the Pediatric Infectious Diseases Society 10, Supplement_1 (2021): S21—S22. http://dx.doi.org/10.1093/jpids/piaa170.068.

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Abstract Background Survival of children with cancer goes hand-on-hand with cancer treatment and improvement of infection care and prevention (ICP). The Hispaniola Island project aims to improve the quality of care and survival for children with cancer in 3 pediatric cancer units by implementing ICP programs in these units with the long-term plan of absorbing such programs into the structure of the hospital care delivery process. We report the 1-year outcomes of establishing ICP standards in pediatric oncology units. Methods We followed the general steps for health promotion when engaging with
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Kelamane, Santosha, Srinath Satyanarayana, Sharath Burugina Nagaraja, et al. "Engaging Informal Private Health Care Providers for TB Case Detection: Experiences from RIPEND Project in India." Tuberculosis Research and Treatment 2021 (June 22, 2021): 1–10. http://dx.doi.org/10.1155/2021/9579167.

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Background. Informal (unqualified) health care providers are an important source of medical care for persons with presumptive TB (PPTB) in India. A project (titled RIPEND) was implemented to engage informal providers for the identification of PPTBs and TB patients in 4 districts of Telangana State, India, during October 2018-December 2019 project period. Engagement involved sensitizing the informal providers about TB, providing them financial incentives to identify PPTBs, and linking these PPTBs to diagnostic and treatment services provided by the Government of India’s National TB Elimination
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Cooperberg, Matthew R., William Meeks, Raymond Fang, Franklin D. Gaylis, William J. Catalona, and Danil V. Makarov. "Time Trends and Variation in the Use of Active Surveillance for Management of Low-risk Prostate Cancer in the US." JAMA Network Open 6, no. 3 (2023): e231439. http://dx.doi.org/10.1001/jamanetworkopen.2023.1439.

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ImportanceActive surveillance (AS) is endorsed by clinical guidelines as the preferred management strategy for low-risk prostate cancer, but its use in contemporary clinical practice remains incompletely defined.ObjectiveTo characterize trends over time and practice- and practitioner-level variation in the use of AS in a large, national disease registry.Design, Setting, and ParticipantsThis retrospective analysis of a prospective cohort study included men with low-risk prostate cancer, defined as prostate-specific antigen (PSA) less than 10 ng/mL, Gleason grade group 1, and clinical stage T1c
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P., Rangachari, Dellsperger K.C., Fallaw D., et al. "Creating a foundation for implementing an electronic health records (EHR)-integrated Social Knowledge Networking (SKN) system on medication reconciliation." Journal of Hospital Administration 7, no. 2 (2018): 36. http://dx.doi.org/10.5430/jha.v7n2p36.

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Background: In fall 2016, Augusta University received a two-year grant from AHRQ, to implement a Social Knowledge Networking (SKN) system for enabling its health system, AU-Health, to progress from “limited use” of electronic health records (EHR) Medication Reconciliation (MedRec) Technology, to “meaningful use”. Phase 1 sought to identify a comprehensive set of issues related to EHR MedRec encountered by practitioners at AU-Health. These efforts helped develop a Reporting Tool, which, along with a Discussion Tool, was incorporated into the AU-Health EHR, at the end of Phase 1. Phase 2 (curren
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Ferhanoglu, Burhan, Marta Zerga, Mubarak Al-mansour, et al. "Use of Positron Emission Tomography in Patients with Classical Hodgkin Lymphoma Outside of Europe and North America: Results from the International, Multi-Center, Retrospective B-Holistic Study." Blood 138, Supplement 1 (2021): 1397. http://dx.doi.org/10.1182/blood-2021-145838.

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Abstract Background: Positron emission tomography-computed tomography (PET-CT) is used for staging and response assessment in classical Hodgkin lymphoma (cHL) and for evaluation and management of refractory/relapsed Hodgkin lymphoma (RRHL). According to the World Health Organization's Global Atlas of Medical Devices 2017 report, 92-95% of lower-middle and low-income countries have no PET/CT unit, and only 3% of upper-middle income countries have 1 PET scanner/million people, versus 29% of high-income countries. Real-world data on PET scan use in cHL and RRHL outside Europe and North America ar
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Lai, Catherine, Adam Bagg, Lindsay Gurska, Shelby Sullivan, Jeffrey Carter, and Cherilyn Heggen. "Optimizing the Integration of Genetic Testing in AML Care in Community Practice: Insights from a Quality Improvement Initiative." Blood 142, Supplement 1 (2023): 7277. http://dx.doi.org/10.1182/blood-2023-172976.

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Background The treatment landscape for acute myeloid leukemia (AML) is rapidly evolving, and with many of the more recently FDA approved treatments being targeted therapies, timely and actionable molecular and cytogenetic testing is critical to the management of AML patients. However, many challenges and barriers to optimal testing workflows impede clinicians' ability to integrate genetic testing in treatment decision-making. To improve quality care related to genetic testing in AML, we conducted a quality improvement (QI) study focused on evidence-based integration of genetic testing into rou
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Manga, M. M., M. Ibrahim, U. M. Hassan, et al. "Empirical antibiotherapy as a potential driver of antibiotic resistance: observations from a point prevalence survey of antibiotic consumption and resistance in Gombe, Nigeria." African Journal of Clinical and Experimental Microbiology 22, no. 2 (2021): 273–78. http://dx.doi.org/10.4314/ajcem.v22i2.20.

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Background: Empirical use of antibiotics is a standard practice in the treatment of infections worldwide. However, its over utilization without subsequent culture and antibiotic susceptibility testing could be a major driver of resistance.Over reliance on empirical antibiotherapy is common in most developing countries where antibiotic policies and availability or utilization of clinical microbiology laboratory are suboptimal. A standardized approach to point prevalence survey (PPS) on antimicrobial use (AMU) in hospitals was employed to assess the antimicrobial prescribing practices in Federal
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Poh, Kian-Keong, Hong Yang, Abdul Razakjr Omar, James WL Yip, Yiong-Huak Chan, and Lieng-Hsi Ling. "Clinically Compressed Digital Echocardiography: A Patient-safe Alternative to Videotape Review." Annals of the Academy of Medicine, Singapore 36, no. 8 (2007): 662–71. http://dx.doi.org/10.47102/annals-acadmedsg.v36n8p662.

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Introduction: Digital storage of echocardiographic data offers logistical advantages over videotape archival. However, limited information is available on the accuracy of clinically compressed digitised examinations, an important consideration for patient safety. Materials and Methods: Transthoracic echocardiograms of 520 consecutive patients were prospectively acquired digitally and on videotape. Two echocardiologists, in consensus, reported studies in both formats sequentially. Using the videotape as a reference, the significance of any reported differences was graded from both imaging and c
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Budiarto, Arif, Kevin C. H. Tsang, Andrew M. Wilson, Aziz Sheikh, and Syed Ahmar Shah. "Machine Learning–Based Asthma Attack Prediction Models From Routinely Collected Electronic Health Records: Systematic Scoping Review." JMIR AI 2 (December 7, 2023): e46717. http://dx.doi.org/10.2196/46717.

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Background An early warning tool to predict attacks could enhance asthma management and reduce the likelihood of serious consequences. Electronic health records (EHRs) providing access to historical data about patients with asthma coupled with machine learning (ML) provide an opportunity to develop such a tool. Several studies have developed ML-based tools to predict asthma attacks. Objective This study aims to critically evaluate ML-based models derived using EHRs for the prediction of asthma attacks. Methods We systematically searched PubMed and Scopus (the search period was between January
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Stocchi, Luca, Heidi Nelson, Daniel J. Sargent, et al. "Impact of Surgical and Pathologic Variables in Rectal Cancer: A United States Community and Cooperative Group Report." Journal of Clinical Oncology 19, no. 18 (2001): 3895–902. http://dx.doi.org/10.1200/jco.2001.19.18.3895.

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PURPOSE: Substantial and successful effort has been focused on decreasing the risk of local failure after rectal cancer surgery through the use of adjuvant therapies. Our study examined data from studies conducted by United States cooperative groups to investigate the impact of surgical and pathologic variables in rectal cancer outcomes. PATIENTS AND METHODS: Surgical and pathologic reports from 673 patients with stage II/III rectal cancer enrolled onto three adjuvant clinical trials were reviewed for tumor and surgical variables. Additional information on individual institutions and operating
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El-Kotob, Rasha, Justin Rodriguez Pagcanlungan, B. Catharine Craven, Catherine Sherrington, Marina Mourtzakis, and Lora Giangregorio. "Researchers’ Perspectives on Adverse Event Reporting in Resistance Training Trials: A Qualitative Study." Applied Physiology, Nutrition, and Metabolism, April 20, 2022. http://dx.doi.org/10.1139/apnm-2022-0012.

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The objectives of our study were to understand researchers' current practices and perspectives on adverse event (AE) reporting in clinical trials of resistance training (RT), and identify barriers and facilitators of AE reporting. We conducted web conference or telephone-based one-on-one semi-structured interviews with 14 researchers who have published RT studies in individuals with or without health conditions. We audio-recorded and transcribed the interviews, and analyzed data using the thematic framework method. Four themes were identified in the context of RT studies: 1) researchers lack g
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ALFadhalah, Talal, and Hossam Elamir. "Patient safety and leadership style in the government general hospitals in Kuwait: a multi-method study." Leadership in Health Services, November 4, 2021. http://dx.doi.org/10.1108/lhs-07-2021-0062.

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Purpose This study aims to evaluate the relationships between leadership style and reported incidents, reporting practices and patient safety initiatives in Kuwaiti hospitals. Design/methodology/approach This cross-sectional and retrospective quantitative multi-centre study was conducted in a secondary care setting. The multifactor leadership questionnaire and the patient safety questionnaire were distributed in six general hospitals to a sample of physicians, nurses and pharmacists. Incident reports were reviewed in each hospital to assess reporting practices. Findings The hospital with the m
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Song, Junmin, Marco Solmi, Andre F. Carvalho, Jae Il Shin, and John PA Ioannidis. "Twelve years after the ARRIVE guidelines: Animal research has not yet arrived at high standards." Laboratory Animals, September 20, 2023. http://dx.doi.org/10.1177/00236772231181658.

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The reproducibility crisis across animal studies jeopardizes the credibility of the main findings derived from animal research, even though these findings are critical for informing human studies. To clarify and improve transparency among animal studies, the ARRIVE reporting guidelines were first announced in 2010 and upgraded to version 2.0 in 2020. However, compliance with and awareness of those reporting guidelines has remained suboptimal. Journal editors should encourage the authors to adhere to those guidelines. Authors, editors, referees, and reviewers should be aware of the ARRIVE guide
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Khan, Mohammed I. U., Hartirath K. Brar, Cynthia Y. Sun, et al. "The reporting of pilot and feasibility studies in the top dental specialty journals is suboptimal." Pilot and Feasibility Studies 8, no. 1 (2022). http://dx.doi.org/10.1186/s40814-022-01182-1.

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Abstract Background Pilot and feasibility studies (PAFS) are smaller investigations seeking to assess the feasibility of conducting a larger more definitive study. In late 2016, the CONSORT statement was extended to disseminate good practices for reporting of randomized pilot and feasibility trials. In this quality assurance review, we assessed whether PAFS in the top dental speciality journals adhere to good practices of conduct and reporting, by prioritizing assessment of feasibility and stating pre-defined progression criteria to inform the decision to pursue funding for a larger trial. Met
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Sharif, Muhammad Junaid Hassan, Ghulam Murtaza, Zelal Kharaba, et al. "An Exploration of Knowledge, Attitude, and Practices of Physicians toward Pharmacovigilance at Tertiary Care Hospitals in Khyber-Pakhtunkhwa Province, Pakistan." American Journal of Tropical Medicine and Hygiene, September 7, 2021. http://dx.doi.org/10.4269/ajtmh.21-0336.

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Drug safety assures the effectiveness, safety, and security of drugs, vaccines, and other biologicals to protect public health. Medication-related errors coupled with unjudicial medication practices often cause a catastrophic impact on the healthcare system globally. The present study aimed to assess the knowledge, attitude, and practice of physicians toward pharmacovigilance and barriers to adverse drug reaction (ADR) reporting at tertiary care hospitals in Khyber-Pakhtunkhwa (KP) province, Pakistan. A descriptive cross-sectional study was conducted among registered doctors working in seven t
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Sandgren, A., V. Hollo, E. Huitric, and C. Ködmön. "Epidemiology of tuberculosis in the EU/EEA in 2010 – monitoring the progress towards tuberculosis elimination." Eurosurveillance 17, no. 12 (2012). http://dx.doi.org/10.2807/ese.17.12.20124-en.

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The 2012 combined tuberculosis (TB) surveillance and monitoring report for the European Union and European Economic Area identifies a mean annual decline in TB notification rate by 4.4% from 2006 to 2010. Culture confirmation for new pulmonary cases and drug susceptibility testing have increased to 65.6% and 70.8%, but remain under their targets of 80% and 100%, respectively. Reporting of treatment outcome and co-infection with human immunodeficiency virus also remain suboptimal. Strengthened control practices are needed to allow progress towards TB elimination.
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Beaudoin, Ann-Marie, Jan Kee Ho, Adrienne Lam, and Vincent Thijs. "Radiomics Studies on Ischemic Stroke and Carotid Atherosclerotic Disease: A Reporting Quality Assessment." Canadian Association of Radiologists Journal, February 29, 2024. http://dx.doi.org/10.1177/08465371241234545.

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Objective: To assess the reporting quality of radiomics studies on ischemic stroke, intracranial and carotid atherosclerotic disease using the Image Biomarker Standardization Initiative (IBSI) reporting guidelines with the aim of finding avenues of improvement for future publications. Method: PubMed database was searched to identify relevant radiomics studies. Of 560 articles, 41 original research articles were included in this analysis. Based on IBSI radiomics reporting guidelines, checklists for CT-based and MRI-based studies were created to allow a structured and comprehensive evaluation of
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Ashkir, Z., Z. Teoh, S. Ganesananthan, et al. "Medication adherence assessment and reporting in cardiovascular randomised controlled trials." European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.2865.

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Abstract Background Despite the knowledge that suboptimal adherence to medications may have an impact on the impact of treatment interventions, the assessment and reporting of medication adherence in cardiovascular randomised controlled trials has not been well studied. In this review we sought to study the differences in medication adherence assessment and reporting in cardiovascular randomised controlled trials (RCTs) comparing interventional procedures to medical therapy alone in four major cardiovascular conditions: coronary disease (CAD), atrial fibrillation (AF), heart failure (HF) and h
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Najjar-Debbiny, Ronza, Bibiana Chazan, Rona Lobl, et al. "Healthcare-associated infection prevention and control practices in Israel: results of a national survey." BMC Infectious Diseases 22, no. 1 (2022). http://dx.doi.org/10.1186/s12879-022-07721-8.

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Abstract Background Healthcare-associated infection (HAI) is a common and largely preventable cause of morbidity and mortality. The COVID-19 pandemic has presented unprecedented challenges to health systems. We conducted a national survey to ascertain hospital characteristics and the use of HAI prevention measures in Israel. Methods We e-mailed surveys to infection prevention and control (IPC) leads of acute care hospitals in Israel. The survey included questions about the use of practices to prevent catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infec
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Oliveira, Nórton Luís, Cíntia Ehlers Botton, Angélica Trevisan De Nardi, and Daniel Umpierre. "Methodological quality and reporting standards in systematic reviews with meta-analysis of physical activity studies: a report from the Strengthening the Evidence in Exercise Sciences Initiative (SEES Initiative)." Systematic Reviews 10, no. 1 (2021). http://dx.doi.org/10.1186/s13643-021-01845-9.

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Abstract Background Several resources have been developed (e.g., reporting guidelines) to promote high-standard practices in health research. However, there was no continuous and systematic assessment of recommended practices in published systematic reviews with meta-analysis (SRMAs), which increases the usability of the available resources. Therefore, we aimed to assess the methodological and reporting standards in SRMAs of physical activity studies. This report presents the main results of the SEES Initiative in 2019. Methods Our approach is based on a prospective systematic review methodolo
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