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Academic literature on the topic 'Substance Use Diso'
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Journal articles on the topic "Substance Use Diso"
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Al’tshuler, L. V., R. I. Il’kaev, and V. E. Fortov. "Use of powerful shock and detonation waves to study extreme states of matter*." Physics-Uspekhi 64, no. 11 (2022): 1167–79. http://dx.doi.org/10.3367/ufne.2021.09.039092.
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Abstract This article is written on the basis of a report given 10 January 2003 at the International Scientific Conference, The Nuclear Age: Science and Society, dedicated to the 100th anniversary of the birth of Igor’Vasil’evich Kurchatov. It presents the results of work on the experimental study of substance properties under high pressure shock waves, briefly describes the use of super-strong magnetic fields for the study of substances at high pressure, presents the results of computational and theoretical research methods, and presents some results of studies of substance properties using liner systems in high-power pulsed electrophysical facilities (VNIIEF disk explosion-magnetic generators and USA Pegasus and ATLAS capacitor banks).
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Novikova, A. V., N. G. Pravdyuk, and N. A. Shostak. "Cellular and molecular aspects of degenerative disc disease and potential strategies of biological therapy." Clinician 14, no. 1-2 (2020): 42–54. http://dx.doi.org/10.17650/1818-8338-2020-14-1-2-42-54.
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Back pain is one of the main global health problems with a high level of prevalence and patients’ disability. In most cases, it is associated with degenerative spine damage (degenerative disc disease), dorsopathy, discopathy (M51 and M53 according to the International Classification of Diseases, 10th revision), affecting all levels of the intervertebral disc (IVD) (cytological, chemical and biochemical) as a whole as well as biological molecules that regulate homeostasis of the disc intercellular substance (growth factors, pro-inflammatory cytokines, enzymes). A key point in IVD dehydration is that catabolic processes predominate over anabolic ones due to changed gene expression in the corresponding biologically active molecules, disc angiogenesis and neoinnervation of the structures of the fibrous ring and pulpous nucleus. The latter is responsible for chronic pain in patients.Cells supporting homeostasis in nucleus pulpous, chondrocytes, continuously synthesize and restore proteoglycans and hyaluronic acid in nucleus pulpous, restoring shock-absorbing functions of the vertebral-motor segment. Decreased activity and death of chondrocytes in the avascular disc structure is a serious problem for reparative medicine. In accordance with IVD molecular-cellular mechanisms, numerous approaches to treat degenerative disc disease are being developed, each of which, influencing one of the links in the pathogenesis, has a direct or indirect effect on IVD repair.The article describes morphology, pathogenesis and genetics of degenerative disc disease, as well as main modern strategies of biological therapy: tissue engineering, biologically active substances locally used in IVD matrix, including PRP therapy (Platelet Rich Plasma therapy), methods of gene (using the viral vector) and cell therapy, as well as experience in the local use of genetically engineered biological products. Most successful studies are a combination of cell and gene therapy with the use of synthesized matrices.
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Jovanovic, Predrag, Paraskeva Hentova-Sencanic, Lepsa Zoric, Maja Petrovic, and Marija Trenkic-Bozinovic. "Unilatelaral iris plateau syndrome after the use of ecstasy." Vojnosanitetski pregled 66, no. 6 (2009): 487–89. http://dx.doi.org/10.2298/vsp0906487j.
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Bacground. Courmon street name for 3,4-Methylenedioxymethamphetamine (MDMA) is ecstasy. This widely abused 'recreational' drug causes both an increased release of monoamine neurotransmitters, including serotonine and dopamine, and an increased reuptake inhibition of serotonin. As a consequence, mydriasis and increased intraocular pressure (IOP) in predisposed patients occur. We present herein a rare case of acute increased IOP after use of ecstasy. Case report. A female patient, aged 38 years, visited doctor complaing of a decreased vision acuity and severe pain in the left eye and in the left part of the head. The initial treatment was urgent antiglaucomatous therapy followed by withdrawal of subjective problems of the patient and improvement of objective finding. History taking procedure reveled that just before the onset of the pain the patient had used ecstasy and had had similar 'experience' 6 years ago after cocaine snorting. She had not been to a doctor although she had experienced sporadic migrenous pain. Previous medical records excavation of revealed optic disk (cup-to-dise C/D=06), Bjerum arcuate scotoma and iris plateau with narrow chamber angle (Scheie II- III) so the diagnosis was a rare unilateral iris plateau syndrome of the left eye. Although the patient was given some pieces of information about the dangerous and possible deadly consequences of psychoactive substance abuse, she has not continue the treatment. Conclusion. Ecstasy abuse might cause a complete loss of vision, thus medicametous and surgical treatment are obligatory.
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Mikulionok, I. O. "FERROMAGNETIC MATERIALS USE FOR PROVIDING THE NECESSARY THERMAL MODE OF PROCESSING EQUIPMENT (REVIEW)." Energy Technologies & Resource Saving, no. 1 (March 20, 2019): 60–72. http://dx.doi.org/10.33070/etars.1.2019.06.
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A new approach to providing the necessary temperature of technological equipment of various industries, in particular, chemical, food, microbiological, heat and power, and therefore a stable thermal mode of processing the flows of substances and materials that are in the specified equipment is proposed. It has been proposed to make working bodies and elements of equipment in contact with the flows of the substances and materials being processed from magnetic material with a phase transition temperature of the second type (Curie point), which corresponds to the temperature of the technological process. The designs of tubular heat exchangers, dryers, packed and disc mass transfer columns, separators, equipment for the processing of thermoplastics (extrusion head, static mixers, worm extruder), as well as bulk feeder are considered. Bibl. 19, Fig. 15.
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Meinisasti, Resva, Zamharira Muslim, Krisyanella, and Raden Sunita. "The Effectiveness Test of Betel Leaf Ethanol Extract Cream (Piper Betle Linn) Toward Propionibacterium acnes Bacterial Growth." Bioscientia Medicina : Journal of Biomedicine and Translational Research 4, no. 2 (2020): 10–17. http://dx.doi.org/10.32539/bsm.v4i2.112.
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Background: One of skin diseases that is frequently taking attention among teenagers and young adults is acne or in medical term called acne vulgaris. Acne treatment can be treated by repairing follicular abnormalities, decreasing sebum production, decreasing the number of Propionibacterium acnes colonies and reducing inflammation of the skin. The bacterial population of Propionibacterium acnes can be reduced by giving an antibacterial substance such as erythromycin, clindamycin and benzoyl peroxide. In the treatment of acne we can get antibacterial originating from nature, one of which can be obtained in the secondary metabolism of plants. The extracts and essential oils of betel leaf contain antibacterial and antifungal activities. The effectiveness of the use of betel leaf ethanol extract (Piper betle Linn) in acne treatment can be improved by creating formulations in form of cream preparations. Formulations in cream preparations will affect the amount and speed of active substances that can be absorbed. Objectives: To determine the effectiveness of the ethanol extract cream of betel leaf (piper betle linn) cream in formulas with what percentage of active substance has the most-inhibitory effect on the growth of Propionibacterium acnes. Methods:The study used experimental research. Propionibacterium acnes samples were diluted in 0.9% physiological NaCl sterile and embedded in Nutrient Agar (NA) media. The media was inserted into an incubator at 37 ° C for 24 hours. The test of antibacterial activity used the disk diffusion method. The antibacterial activity test results were statistically analyzed using the Statistical Product Services Solution (SPSS 17) program with a confidence level of 95% (α = 0.05). Results: The three creams containing betel leaf ethanol extracts at percentages of 5%, 10% and 15% for each had inhibitory zones: 9.8 mm, 15.85 mm, 17.35 mm. Conclusion: Cream that contains 15% active substance has the strongest inhibition.
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Pihut, Malgorzata, and Andrzej Gala. "The Application of Intra-Articulr Injections for Management of the Consequences of Disc Displacement without Reduction." International Journal of Environmental Research and Public Health 17, no. 13 (2020): 4726. http://dx.doi.org/10.3390/ijerph17134726.
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The aim of the study was to make a comparative studies on the effectiveness of platelet rich plasma (PRP) and hyaluronic acid (HA) in intra-articular injections to the temporomandibular joints—in double blind studies application—based on the analysis of selected clinical parameters of functional efficiency and the mean value of joint’s pain intensity before and after management. The study enrolled a group of 100 patients, aged 21 to 43 years, of both sexes, who came for the prosthodontic treatment. All patients had II b group of disorder according to the Research Diagnostic Criteria/Temporomandibular Disorder, and were consecutively, alternately assigned to the groups, 50 patients in each. Study group PRP was treated with intra-articular injection of platelet rich plasma and study group HA had injection with hyaluronic acid. The examination was double-blind, so that the injecting physician and the patient were not informed what kind of medicinal substance they received in the joint injection. The final selected clinical parameters did not differ statistically significantly between the groups, what means that both administered substances were effective in the repair of intra-articular structures. The results of research showed that the use of PRP and HA in intraarticular joint’s injections positively affects in selected clinical parameters and decrease of the pain in temporomandibular joints in the case of disc displacement without reduction.
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ANTONENKO, Artem, Tetiana BROVENKO, Olena VASILENKO, Yuliia ZEMLINA, Galina TOLOK, and Igor GRISCHENKO. "USE OF NON-TRADITIONAL RAW MATERIALS IN COLD SNACK TECHNOLOGY." HERALD OF KHMELNYTSKYI NATIONAL UNIVERSITY 295, no. 2 (2021): 239–44. http://dx.doi.org/10.31891/2307-5732-2021-295-2-239-244.
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The purpose of this research is to substantiate and develop the technology of vegetarian cold snacks “VegoShuba”. The object of the study is the technology of salad with the addition of nori leaves, Adyghe cheese, sour cream, asafetida and dried fruits “VegoShuba”. The article substantiates the expediency of using nori leaves, Adyghe cheese, vegetarian mayonnaise, chia seeds, asafetida and dried fruits (prunes and dried apricots) in the technology of vegetarian salad “VegoShuba”. On the basis of technological developments the technology of vegetarian salad “VegoShuba” is developed. The paper presents the results of research on quality indicators and calculates the chemical composition of the developed dish. During technological tests in the prototypes, herring was replaced with nori leaves, eggs – with Adygea cheese, mayonnaise – with sour cream with turmeric and black salt. The optimal amount of chia seeds, Adyghe cheese, asafetida and dried fruits was determined by organoleptic evaluation. After a study of organoleptic characteristics, it was determined that the highest organoleptic evaluation was obtained by experiment with the addition of chia seeds – 0.2 g, asafetida – 0.2 g, prunes – 3 g and dried apricots – 3 g. Analyzing the chemical composition of the vegetarian analogue of the classic dish “Herring under a fur coat” it is possible to observe considerable increase in the content of nutrients. Based on the analysis of the daily nutrient requirements of VegoShuba salad, there is an increase in the satisfaction of daily nutrient requirements, with the exception of vitamin B12. This dish can be recommended in the appropriate restaurants. Taking into account the research and calculations, a model of the quality of the developed dish was built, it reflects the percentage of nutrients in salads to the daily intake. Summarizing the results, we can conclude that the developed dish “VegoShuba” using nori leaves, Adyghe cheese, sour cream, chia seeds, asafetida and dried fruits in certain quantities have compared to the control sample increased biological value due to the variety of ingredients that have composition of biologically active substances and valuable nutrients, so it is a worthy alternative in vegetarian cuisine. The developed dish “VegoShuba” can be recommended for implementation in restaurants of Ukraine.
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Martinotti, Giovanni, Cristina Merino Del Villar, Andrés Garcia Cordoba, et al. "Club Drugs and Psychiatric Sequelae: An Issue of Vulnerability and Previous Psychiatric History." International Journal of Environmental Research and Public Health 18, no. 13 (2021): 6944. http://dx.doi.org/10.3390/ijerph18136944.
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The pursuit of pleasure among clubbers and disco-goers often involves drug use. However, whether substance use may represent a relevant risk factor contributing to the development of psychiatric symptoms and of mental illness remains debated. The purposes of this study were to evaluate the percentage of subjects who developed long-lasting psychiatric symptoms in a sample of subjects reporting use of substances in nightclubs, and to evaluate the role of a previous psychiatric diagnosis in these subjects. Data were collected during three consecutive years in dedicated nursing units inside all the nightclubs of Ibiza, in emergency hospital rooms at the Can Misses Hospital and inside the psychiatric ward. A total of 10,163 subjects required medical assistance inside discos in the medical-nursing units, of which 223 required transfers to hospital emergency rooms. Of these, 110 required subsequent psychiatric hospitalization. Ninety-one (82.7%) of these patients had a positive psychiatric history, which was also found in thirty-one of the 113 subjects (27.4%) not requiring psychiatric hospitalization. Negative psychiatric history was negatively associated with hospitalization (Coefficient = −2.574; p = 0.000) and for subjects with a negative psychiatric history the odds to be hospitalized changed by a factor of 0.076. Gender, age, civil status and nationality were not significant predictors of hospitalization. Overall, the number of subjects who developed major psychiatric disorders appeared to be limited. However, the presence of a psychiatric history here played a crucial role. Club drugs are therefore able to induce psychiatric sequelae requiring hospitalization mainly in subjects who are already vulnerable from a psychopathological point of view.
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Jaramillo, Héctor E. "Evaluation of the Use of the Yeoh and Mooney-Rivlin Functions as Strain Energy Density Functions for the Ground Substance Material of the Annulus Fibrosus." Mathematical Problems in Engineering 2018 (November 7, 2018): 1–10. http://dx.doi.org/10.1155/2018/1570142.
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Due to the importance of the intervertebral disc in the mechanical behavior of the human spine, special attention has been paid to it during the development of finite element models of the human spine. The mechanical behavior of the intervertebral disc is nonlinear, heterogeneous, and anisotropic and, due to the low permeability, is usually represented as a hyperelastic model. The intervertebral disc is composed of the nucleus pulposus, the endplates, and the annulus fibrosus. The annulus fibrosus is modeled as a hyperelastic matrix reinforced with several fiber families, and researchers have used different strain energy density functions to represent it. This paper presents a comparative study between the strain energy density functions most frequently used to represent the mechanical behavior of the annulus fibrosus: the Yeoh and Mooney-Rivlin functions. A finite element model of the annulus fibrosus of the L4-L5 segment under the action of three independent and orthogonal moments of 8 N-m was used, employing Abaqus software. A structured mesh with eight divisions along the height and the radial direction of annulus fibrosus and tetrahedron elements for the endplates were used, and an exponential energy function was employed to represent the mechanical behavior of the fibers. A total of 16 families were used; the fiber orientation varied with the radial coordinate from 25° on the outer boundary to 46° on the inner boundary, measuring it with respect to the transverse plane. The mechanical constants were taken from the reported literature. The range of motion was obtained by finite element analysis using different values of the mechanical constants and these results were compared with the reported experimental data. It was found that the Yeoh function showed a better fit to the experimental range of motion than the Mooney-Rivlin function, especially in the nonlinear region.
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Romeo, Alfredo, Marianna Chierchia, Carolina Baiano, and Dante Ronca. "Anatomic substrate to pain originating in the disc and chronic low back pain posture damage resolution." Ozone Therapy 1, no. 3 (2017): 61. http://dx.doi.org/10.4081/ozone.2016.6472.
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Chronic low back pain is a disease that most often affects people between 45 and 64 years. The incidence of low back pain goes from 60 to 90% and the annual incidence is 5%. Often low back pain is accompanied or replaced by an irradiated lower limb pain, configuring the symptomatology of lumboradiculalgia, whose most frequent cause is the disco-radicular conflict. The cause of the onset of pain, even excruciating, in cases of radicular compression of disc origin is not yet clear. Low back pain of disc origin is thought to be caused by direct mechanical compression factors; by indirect mechanical factors ischemia or venous stasis of vasa nervorum; and by type of immune-mediated inflammatory factors (reaction hernia) and/or biochemical evidence related to the disc type (the presence of substances which induce the inflammatory reaction). When a patient is suffering by chronic low back pain, apart from the algic problem, a series of changes in posture will occur, which contribute to worsen low back pain itself. The effects of a polluted posture and, therefore, the muscle retraction manifest in the joints in the form of compression, axial rotation and translation, resulting in modifications of the skeletal morphology (scoliotic attitudes, hyperkyphosis, valgus and varus of the knee, <em>etc</em>.) and possibly evolving into important postural disorders. Currently, the treatment of chronic low back pain and postural secondary disorders is still an open problem. The aim of this preliminary study is: i) to highlight the high incidence of low back pain by providing evidence that there is an anatomical substrate to low back pain originating in the disc; ii) and to assess the effects of the use of oxygen-ozone percutaneous paravertebral intramuscular therapy in synergy with a functional rehabilitation program in a group of patients suffering from chronic low back pain. From the data obtained, the combination of percutaneous paravertebral intramuscular oxygen-ozone therapy with functional rehabilitation is confirmed as an effective and safe method, whose favorable results are evident at the level of lumbar pain symptoms, postural secondary abnormalities, disability in activities of daily living, the mood and tone of the psychological state.