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Relevant bibliographies by topics / Substituted Imidazole

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Academic literature on the topic 'Substituted Imidazole'

Author: Grafiati

Published: 2 June 2025

Last updated: 19 July 2025

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Journal articles on the topic "Substituted Imidazole"

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Ganguly, Swastika, Vatsal Vithlani, Anup Kesharwani, et al. "Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs." Acta Pharmaceutica 61, no. 2 (2011): 187–201. http://dx.doi.org/10.2478/v10007-011-0018-2.

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Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs A series of 1-(2-methyl-4-nitro-imidazol-1-yl)-3-arylaminopropan-2-ones (2a-e), 2-methyl-5-nitro-1-{2-[arylmethoxy] ethyl}-1H-imidazoles (5a-d), and N-(3-hydroxyphenyl)-2-(substituted imidazol-1-yl)alkanamides (8a-e) were synthesized with the aim to develop novel imidazole analogs with broad-spectrum chemotherapeutic properties. Title compounds were evaluated for their anti-HIV and antibacterial activities.

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Singh, Gurvinder P., Saravanan Kaliyaperymal, and Gyanendra K. Sharma. "Microwave-assisted Solvent-free Synthesis of Some New 4-[2-(Substituted phenyl)-4, 5-diphenyl-1H-imidazole-1-yl]-1H-indoles of Biological Interest." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 02 (2024): 253. http://dx.doi.org/10.59467/ijhc.2024.34.253.

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Solvent-free, microwave-assisted synthesis of several new indolyl imidazoles of biological importance is reported. First, indoleamine was condensed with substituted aryl aldehydes to give corresponding Schiff's bases. Then, Schiff's bases were reacted with ammonium acetate and benzil using silica gel as the solid support to yield the corresponding substituted indolyl imidazole derivatives. A comparison between the conventional approach and the microwave-assisted method is also reported in this research. All the synthesized substituted indolyl imidazole derivatives showed good antibacterial act

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Sengee, Gerelt-Ireedui, Narangerel Badraa, and Young Key Shim. "Synthesis and photodynamic activity of new imidazole substituted pyropheophorbide-a derivatives." Journal of Porphyrins and Phthalocyanines 13, no. 07 (2009): 818–22. http://dx.doi.org/10.1142/s1088424609001017.

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Two new imidazole substituted chlorin derivatives, namely (4-[1-imidazolyl]-phenyl)-amide pyropheophorbide-a and (3-[1-imidazolyl]-propyl)-amide pyropheophorbide-a have been synthesized. Their cell viabilities on A549 human lung adenocarcinoma cells were investigated and compared with that of pyropheophorbide-a. According to the phototoxicity study, (4-[1-imidazolyl]-phenyl)-amide pyropheophorbide-a and (3-[1-imidazolyl]-propyl)-amide pyropheophorbide-a were found superior to pyropheophorbide-a with respect to high phototoxicity. This work demonstrates that imidazole substituted chlorin deriva

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Gupta, A. K., A. Jain, S. Mishra, and A. Jiaswal. "Design and Synthesis of Substituted Imidazole Derivatives as Antifungal Agents." International Journal of Drug Design and Discovery 3, no. 4 (2025): 943–54. https://doi.org/10.37285/ijddd.3.4.9.

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In the present study, we have designed, predicted, synthesized and evaluated some new substituted imidazoles derivatives as antifungal agents. Here, a set of 26 substituted imidazole derivatives were investigated for molecular modeling studies using a combination of various molecular descriptors. A sequential multiple linear regression (SQMLR) procedure was used to model the relationships between molecular descriptors and the antifungal activity of the substituted imidazole derivatives. The QSAR analysis of the imidazole analogues furnished topology of molecules and electronic contribution are

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Dutta, Satyajit. "Synthesis and anthelmintic activity of some novel 2-substituted-4,5-diphenyl imidazoles." Acta Pharmaceutica 60, no. 2 (2010): 229–35. http://dx.doi.org/10.2478/v10007-010-0011-1.

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Synthesis and anthelmintic activity of some novel 2-substituted-4,5-diphenyl imidazolesA series of 2-substituted-4,5-diphenyl imidazoles1a-jwere synthesized by refluxing benzil with different substituted aldehydes in the presence of ammonium acetate and glacial acetic acid. Structures of the synthesized compounds were confirmed on the basis of IR,1H NMR and mass spectral data. Compounds1a-jwere screened for anthelmintic activity. Test results revealed that compounds showed paralysis time of 0.24 to 1.54 min and death time of 0.39 to 4.40 min while the standard drugs albendazole and piperazine

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Li, Steven A., Rebecca J. Zheng, Kenneth Sue, et al. "Discovery and Preliminary Structure-Activity Investigation of 3-Substituted-1H-imidazol-5-yl-1H-indoles with In Vitro Activity towards Methicillin-Resistant Staphylococcus aureus." Antibiotics 11, no. 10 (2022): 1450. http://dx.doi.org/10.3390/antibiotics11101450.

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Antibiotics have been the cornerstone of modern medicine saving lives by virtue of being able to cure infectious diseases and to prevent infections in those who are immune compromised. Their intense use has led to a surging increase in the incidence of antibiotic-resistant bacteria resulting in a desperate need for antibiotics with new mechanisms of action. As part of our search for new antimicrobials we have screened an in-house library of compounds and identified two 3-substituted-1H-imidazol-5-yl-1H-indoles as weak growth inhibitors (MIC 16 µg/mL) against methicillin-resistant Staphylococcu

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E.AJILA*, R.ANIZ K.ROY THARA BAI. "SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 1H-SUBSTITUTED 2, 4, 5- TRIPHENYL IMIDAZOLE DERIVATIVES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7367–73. https://doi.org/10.5281/zenodo.1342750.

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<em>On the basis of various literature survey, imidazole derivatives show various activity such as antimicrobial, anti-inflammatory, analgesic, antitubercular, anticancer etc. The possible improvements in the activity can be further achieved by slight modifications in the substituents on the basic imidazole nucleus. Thus imidazole offers better pharmacodynamic characteristics. Furthermore, some imidazole drugs, at high concentrations, could exert direct inhibitory effects on membranes, without interference with sterols and sterol esters. Various recent new drugs developments in imidazole deriv

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Mloston, Grzegorz, and Marcin Jasiński. "Synthesis and selected transformations of 3-oxido-1H-imidazole-4-carboxamides." Collection of Czechoslovak Chemical Communications 75, no. 8 (2010): 871–85. http://dx.doi.org/10.1135/cccc2010012.

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An efficient synthesis of new N-alkyl- and N-aryl-3-oxido-1H-imidazole-4-carboxamides based on exploration of inexpensive, commercially available ethyl acetoacetate, paraformaldehyde and primary amines is described. Representative compounds were tested in selected transformations, such as ‘sulfur-transfer reaction’ leading to imidazole-2-thiones and isomerization to corresponding imidazol-2-ones. Strong intramolecular hydrogen bonding via the N-oxide function results in the reduced reactivity of 3-oxido-1H-imidazole-4-carboxamides in both reactions. Moreover, the palladium catalyzed C(2)-aryla

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Das, Barnali, Arghyadeep Bhattacharyya, Bhaswati Paul, Ramalingam Natarajan, and Swapan Majumdar. "An elegant approach for the synthesis of multisubstituted imidazole via FeCl₃/SiO₂ catalyzed activation of acetals: a photophysical study of an imidazole–carbazole hybrid." RSC Advances 14, no. 45 (2024): 33512–23. http://dx.doi.org/10.1039/d4ra06436d.

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Here, synthesis of substituted imidazoles from benzil, protected carbonyl and NH4OAc/primary amine in the presence of a FeCl3/SiO2 catalyst is reported. The photophysical property of the synthesized imidazole–carbazole hybrid is also investigated.

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Ahmad, Muhammad Saeed, Abu Bakar Siddique, Muhammad Khalid, et al. "Synthesis, antioxidant activity, antimicrobial efficacy and molecular docking studies of 4-chloro-2-(1-(4-methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl)phenol and its transition metal complexes." RSC Advances 13, no. 14 (2023): 9222–30. http://dx.doi.org/10.1039/d2ra08327b.

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Herein, a one-pot synthesis of tetra-substituted imidazole, 4-chloro-2-(1-(4-methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl)phenol (HL), is reported by the reaction of benzil, 5-chlorosalicylaldehyde, ammonium acetate and anisidine.

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Dissertations / Theses on the topic "Substituted Imidazole"

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Norton, Helen Clare. "Functionalised 2-substituted imidazoles in asymmetric catalysis." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427178.

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Meldrum, J. A. "Kinetic and metabolic studies on some substituted-imidazoles using hepatic microsomal monooxygenases." Thesis, University of Strathclyde, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382416.

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Zhang, Xiaoyan. "Design, Synthesis and Biological Activities of 4-Substituted Imidazoles as (alpha)2-Adrenoceptor Agonists /." The Ohio State University, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487865929453611.

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Arico, Joseph William. "3-Substituted Purines: Methodology, Synthesis, and Studies of DNA Hydration in the Minor Groove." Thesis, Boston College, 2010. http://hdl.handle.net/2345/1824.

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Thesis advisor: Mary F. Roberts<br>As the central repository of biological information and ultimate mediator of all processes underlying the activities of living organisms, nucleic acids are the sine qua non for life as we know it. Biological research over the past century and more has revealed much of the structure and function of nucleic acids, revealing in turn how life begins, changes, reproduces, and ends. We glimpse how life has become what it is and perhaps what it may become. This work seeks to understand the ramifications of altering a single nitrogen of the purine nucleoside componen

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Marhadour, Sophie. "Synthèse et évaluation biologique d'imidazo[1,2-a]pyridines et imidazo[1,2-a]pyrazines substituées." Nantes, 2012. https://archive.bu.univ-nantes.fr/pollux/show/show?id=4e0f80d9-0044-48fd-8bbb-b95ca715891a.

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Les molécules basées sur les systèmes hétérocyliques imidazo[1,2-a]pyridine et imidazo[1,2-a]pyrazine ont montré une large variété d'applications thérapeutiques. Ainsi, la conception de nouveaux dérivés d'imidazo[1,2-a]pyridine, substitués en position 2 et 3, mais également d'imidazo[1,2-a]pyrazine, fonctionnalisés en position 6, a été envisagée afin d'élargir le profil d'activité pharmacologique. En particulier, les infections fongiques (Candida albicans, Aspergillus fumigatus) et les maladies parasitaires (Leishmania) représentent un problème majeur de santé publique. Plusieurs classes de co

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Middleton, David Andrew. "The interaction of substituted imidazo[1,2-a]pyridines with model membranes and with the gastric H/K-ATPase." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335768.

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Touzeau, Frédérique. "Syntheses et proprietes pharmacologiques de 2-(4,5-dihydro-1h-2-imidazolyl)-3,4-dihydro-2h-1,4-benzoxazines diversement substituees." Orléans, 1998. http://www.theses.fr/1998ORLE2023.

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L'hypertension arterielle est une pathologie qui concerne plus de 10% de la population adulte. Pour son traitement, il existe toute une gamme de medicaments tres actifs repartis en plusieurs classes distinctes (les diuretiques, les bloquants, les antagonistes calciques, les inhibiteurs de l'enzyme de conversion, les antihypertenseurs centraux). Depuis quelques annees d'autres composes actifs ont ete mis en evidence qui font intervenir de nouveaux recepteurs notamment les recepteurs aux imidazolines. Le but de ce travail est de synthetiser des composes susceptibles d'avoir une activite antihype

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Chiu, Ying-Chang, and 邱盈彰. "Metallomesogens based on N-(2-hydroxy)alkyl substituted imidazole derivatives." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/24548624483347290155.

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博士<br>國立東華大學<br>化學系<br>97<br>Metallomesogens of the types (i) N-(2-hydroxyl)alkyl imidazole coordinated with Silver(I), Gold(I), and Palladium(II) ions (in Chapter II), (ii) Silver(I) and Gold(I) complexes of N-hexadecanyl-N´-(2-hydroxyhexadecanyl) imidazol-2-ylidenes (in Chapter III), and (iii) nanocomposites of Gold nanoparticles embedded in N,N´-di-substituted imidazolium salt (in Chapter IV) are presented. The characterizations, results, and discussions are described in each section.

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Batten, Michael Peter. "Imidazole substituted ligands in late transitional metal catalysis : comparative synthetic, spectroscopic and catalytic studies." Thesis, 2008. https://eprints.utas.edu.au/19252/1/whole_BattenMichaelPeter2008_thesis.pdf.

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This thesis addresses the chemistry of imidazole containing ligands, particularly with respect to their nickel, iron and molybdenum complexes. The ability of many of the nickel and iron complexes to support chain-building olefin insertion reactions is described. The results are presented within the context of the current state-of-theart late transition metal oligo-polymerisation catalysis via an extensive review of the literature.

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Chen, Yu-Jen, and 陳俞臻. "The Synthesis and Photochemistry of Radical Pair Precursors: N-Benzenesulfonyl Substituted Pyrroles, Imidazole and Indole." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/3287f4.

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碩士<br>國立交通大學<br>應用化學系<br>90<br>A series of 39, 47, 52 and 53 in 2-methyltetrahydrofuran glass matrices at 77 K were irradiated with 230-325 nm (NiSO4-filtered, UV light), which gave triplet EPR spectra, and the zero-field splitting (zfs) parameters D' values are 0.0228, 0.0225, 0.0190 and 0.0176 cm-1, respectively. At 4 K, the D' values of 51 and 47 are 0.0239 and 0.0237 cm-1, respectively. The radical pairs derived from 51 (12-44 K) and 47 (8-52 K) both showed linear Curie plots, thereby indicating either the ground state are triplets or that singlet and triplet states are degenerate (≦30 c

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Books on the topic "Substituted Imidazole"

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Shaw, Julian David. Molecular geometry of methyl-substituted benz [A] anthracenes and nucleosides relevant to chemical carcinogenesis: Single crystal X-ray diffraction analyses and refinements of crystal structures of substitated benz (a) anthracenes and imidazole nucleosides, and high-resolution N.M.R. spectroscopy of solutions of hydrocarbons. 1986.

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Book chapters on the topic "Substituted Imidazole"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with imidazolyl substituted phenol." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 7. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65895-6_319.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of polymeric copper(II) complex with imidazolyl substituted phenol." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 7. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65895-6_320.

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Grimmett, M. Ross. "Synthesis of Specifically Substituted Imidazoles and Benzimidazoles." In Imidazole and Benzimidazole Synthesis. Elsevier, 1997. http://dx.doi.org/10.1016/b978-012303190-7/50021-2.

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Barrett, Graham c. "Modifications of the aryl substituents of ß-aryl a-amino acids." In Amino Acid Derivatives. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198558538.003.0016.

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Abstract Phenylalanine and tyrosine have the conventional chemistry of benzene and phenol, respectively when their amino and carboxy groups are protected. Similarly, histidine and tryptophan have the typical behaviour of a 4-substituted imidazole and a 3-substituted indole, respectively.

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Davies, David T. "Isoxazoles, pyrazoles, and isothiazoles." In Aromatic Heterocyclic Chemistry. Oxford University Press, 1992. http://dx.doi.org/10.1093/hesc/9780198556602.003.0004.

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This chapter investigates isoxazoles, pyrazoles, and isothiazoles. Isoxazole, pyrazole, and isothiazole are the parent structures of the 1,2-azole family of heterocycles, having a nitrogen atom plus one other heteroatom in a 1,2-relationship in a five-membered ring. The aromatic sextet is completed by delocalization of the lone pair from the second heteroatom. Consequently, as in pyridine, the nitrogen atoms of the 1,2-azoles have a lone pair available for protonation. However, the 1,2-azoles are significantly less basic than the 1,3-azoles because of the electron-withdrawing effect of the adjacent heteroatom. Isoxazole and isothiazole are essentially non-basic heterocycles, and even pyrazole is a much weaker base than the corresponding 1,3-azole imidazole. As with substituted imidazoles, substituted pyrazoles may exist as a mixture of tautomers. The chapter then looks at the synthesis, electrophilic substitution, and anion chemistry of isoxazoles, pyrazoles, and isothiazoles.

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Saunders, John. "Blockade of angiotensin-II receptors." In Top Drugs. Oxford University Press, 2000. http://dx.doi.org/10.1093/hesc/9780198501008.003.0002.

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This chapter takes a closer look at losartan and valsartan which are used in reducing blood pressure. It gives a brief overview of the factors leading to the synthesis of losartan. Then it describes the two key components required for the convergent route leading to losartan: the preformed imidazole and a substituted biphenyl derivative. The chapter presents the pathways by which losartan has been prepared. It also reviews the synthesis of valsartan, which was first approved in 1996. The process involves the hydrolysis to the primary alcohol via acetate, Swern oxidation, amination with L-valine methyl ester, and acylation with valeric acid chloride, among others.

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Singh, Rohit, and Avneet Kaur. "Substituted Azoles as Non-Nucleoside Reverse Transcriptase Inhibitors Activity." In Strategies for the Synthesis of Heterocycles and Their Applications. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110758.

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This Review article gives an overview of substituted azole based synthetic medicine and their significance application in treating various ailments. The chemical reactions of azoles with other heterocyclic compounds/chemical reagents produce a lot of new substituted molecules, which have plentiful biological actions and potential pharmaceutical applications. Azoles is considered a major class of heterocyclics and worldwide researchers have put great efforts in studying this nucleus in order to design and synthesize various new derived of imidazole and hybrid molecules with the identification of their significant role in many classes of drugs such as antiviral including anti-HIV. Azoles has inspiring molecular geometric structure that offers a suitable skeleton to build newer chemical entities which has encouraged medicinal chemists to design and synthesis of novel and effective molecule as potential therapeutic agents. However, there is an urgent need to study the mechanism of action at molecular level of several pharmacological actions resulting from azoles scaffold through modern methods to furnish safer and effective new molecules for the treatment of various diseases.

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Deshmukh, M. B., S. R. Yankanchi, S. M. Deshmukh, and Bhagawan Patil. "SYNTHESIS AND BIOLOGICAL INVESTIGATIONS OF NEWLY SYNTHESIZED SUBSTITUTED IMIDAZOLE [2, 1-C] [1, 2, 4] TRIAZOLE DERIVATIVES FROM IMIDACLOPRID." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 1. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bdcs1ch7.

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New molecules with promising insecticidal properties like imidazo[2,1-c][124] triazole analogs were synthesized, starting with imidacloprid and bio-assayed. The structures of synthesized molecules were confirmed with diverse modern methods like FT-IR, 1H NMR, 13C NMR, and Mass spectrometry. The synthesized molecules are screened to investigate their insecticidal and anti-bacterial activity. The bioassay screening showed that synthesized compounds chloro (3-(4-chlorophenyl)-7-[(6-chloropyridin-3-yl)methyl]-2,5,6,7-tetrahydro-3H-imidazo [2,1-c] [1,2,4] triazole (4b), the 3-(2-chlorophenyl)-7-[(6-chloropyridin-3-yl)methyl]-2,5,6,7-tetrahydro-3H-imidazo [2,1-c] [1,2,4] triazole (4c), nitro(7-[(6-chloropyridin-3-yl)methyl]-3-(4-nitrophenyl)-2,5,6,7-tetrahydro-3H-imidazo[2,1-c] [1,2,4] triazole (4d) and 7-[(6-chloropyridin-3-yl)methyl]-3-(2-nitrophenyl)-2,5,6,7-tetrahydro-3H-imidazo[2,1-c] [1,2,4]triazole (4e) showed higher bioactivities than imidacloprid against Hubner (H.armigera), Mealybugs (Planococcus citri), and Mango hoppers (Idioscopus clypealis), and tobacco and tomato bacterial wilt. The results of biological activity were determined. Compounds with electron-withdrawing groups showed potential as vector control agents.

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Rossi, Renzo, Marco Lessi, Chiara Manzini, and Fabio Bellina. "Synthesis and Biological Profiles of 4,5-, 1,5-, and 1,2-Diaryl-1 H -imidazoles." In Vicinal Diaryl Substituted Heterocycles. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-08-102237-5.00004-3.

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Menge, W. M. P. B., and H. Timmerman. "Substituted imidazoles, the key to histaminergic receptors." In Pharmacochemistry Library. Elsevier, 1998. http://dx.doi.org/10.1016/s0165-7208(98)80028-7.

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Conference papers on the topic "Substituted Imidazole"

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Chen, Yue, Huey J. Chen, and W. Paul Jepson. "Effects of Multiphase Flow on Corrosion Inhibitor." In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99012.

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Abstract This paper investigates the inhibition performance of a typical imidazoline based inhibitor under multiphase flow. Electrochemical impedance spectroscopy (EIS) measurements were carried out in a 101.6 mm I.D., 15 m long acrylic flow loop using ASTM substitute saltwater and carbon dioxide gas. This flow loop system can generate slug flow, full pipe flow and other multiphase flow patterns. Effects of different flow conditions on inhibition performance of this typical inhibitor were examined. The system was maintained at a pressure of 0.136 MPa and a temperature of 40 °C. EIS measurement

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Ahmed, Md Soif, Chinmoy Biswas, K. S. Srivishnu, L. Giribabu, V. R. Soma, and Sai Santosh Kumar Raavi. "Ultrafast Excited State Dynamics of Triphenyl Imidazole Thiophene Substituted Phthalocyanines." In International Conference on Ultrafast Phenomena. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/up.2022.tu4a.11.

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Thiophene Substituted Copper Phthalocyanines (ThPcCu), used as hole transport material in perovskite solar cell fabrication, is investigated for its ultrafast excited state dynamics. ThPcCu data shows long-lived GSB kinetics ≈ 4.5ns and long-lived triplets.

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Semenyuta, Ivan, Diana Hodyna, Anastasia Griniukova, Sergiy Rogalsky, and Larysa Metelytsia. "LONG-CHAIN N-SUBSTITUTED IMIDAZOLE DERIVATIVES WITH ANTICANCER ACTIVITY AGAINST CHRONIC MYELOID LEUKEMIA." In EDUCATION AND SCIENCE OF TODAY: INTERSECTORAL ISSUES AND DEVELOPMENT OF SCIENCES. European Scientific Platform, 2024. http://dx.doi.org/10.36074/logos-29.03.2024.041.

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Santos, Marilia S., Manoel T. Rodrigues Jr., and Fernando Coelho. "A simple access to ionic liquids using N-substituted imidazole derivatives from Morita-Baylis-Hillman adducts." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201310110101.

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Jovanović-Šanta, Suzana S., Aleksandar M. Oklješa, Antos B. Sachanka, Yaraslau U. Dzichenka, and Sergei A. Usanov. "17-SUBSTITUTED STEROIDAL TETRAZOLES – NOVEL LIGANDS FOR HUMAN STEROID-CONVERTING CYP ENZYMES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.336js.

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In animal and human organisms, there are many enzymes, members of the family of heme- containing proteins, cytochromes P450 (CYPs), included in the biosynthesis and metabolism of many biomolecules, as cholesterol, bile acids, sex, and corticosteroid hormones, as well as in metabolism of drugs and xenobiotics. It is also well-known that different imidazole and triazole derivatives are efficient inhibitors of CYPs activity. In this study, we present in vitro screening of binding of novel androstane derivatives with tetrazole- containing substituents in position 17 to human recombinant steroid-co

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Manteghi, Faranak, and Hamed Ramezanalizadeh. "One-pot synthesis of substituted imidazole derivatives by a new designed BiFeO₃/CuWO₄ heterojunction nanocatalyst ." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-a015.

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Maleki, Ali, Zahra Alirezvani, and Nakisa Ghamari. "UHP as a mild and efficient catalyst for the synthesis of substituted imidazoles via multicomponent condensation strategy." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a031.

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Farah, Said M., Madhavi Gangapuram, Nelly Mateeva, Bereket Mochona, Tiffany W. Ardley, and Kinfe K. Redda. "Abstract 3263: Synthesis of substituted N-(4-(6-methyl-1H-benzo[d]imidazol-2-yl)-5,6-dihydropyridin-1(2H)-yl) benzamide/benzenesulfonamide as anticancer agents." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3263.

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Nezamabadi, Atefeh. "1,3,5-Tris (2-hydroxyethyl) isocyanurate-Cu(II) functionalized magnetic graphene oxide (MGO-THEIC-CuII): a highly efficient and recoverable nanocatalyst for the one-pot synthesis of substituted imidazoles under microwave irradiation." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04780.

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