Academic literature on the topic 'Subunit vaccines'

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Journal articles on the topic "Subunit vaccines"

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Milic, Nenad, Jakov Nisavic, Andrea Zoric, Dejan Krnjaic, Marina Radojicic, and Aleksandar Stanojkovic. "Overview of current advances in the development of subunit and recombinant vaccines against Newcastle disease virus." Biotehnologija u stocarstvu 33, no. 1 (2017): 1–11. http://dx.doi.org/10.2298/bah1701001m.

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Newcastle disease virus (NDV) is one of the most important viral pathogens of avian species and the causative agent of atypical fowl plague, a highly contagious and economically important disease characterized by high mortality rates and reduction of egg production. The HN and F proteins are the main targets for immune response to NDV. Vaccination of poultry with live and inactivated NDV vaccines is the most effective method of control and prevention of Newcastle disease, however due to their disadvantages, efforts are being invested into developing subunit vaccines. To this end, the NDV HN an
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McCraw, Dustin M., John R. Gallagher, and Audray K. Harris. "Characterization of Influenza Vaccine Hemagglutinin Complexes by Cryo-Electron Microscopy and Image Analyses Reveals Structural Polymorphisms." Clinical and Vaccine Immunology 23, no. 6 (2016): 483–95. http://dx.doi.org/10.1128/cvi.00085-16.

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ABSTRACTInfluenza virus afflicts millions of people worldwide on an annual basis. There is an ever-present risk that animal viruses will cross the species barrier to cause epidemics and pandemics resulting in great morbidity and mortality. Zoonosis outbreaks, such as the H7N9 outbreak, underscore the need to better understand the molecular organization of viral immunogens, such as recombinant influenza virus hemagglutinin (HA) proteins, used in influenza virus subunit vaccines in order to optimize vaccine efficacy. Here, using cryo-electron microscopy and image analysis, we show that recombina
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Svetoch, E. A., I. A. Dyatlov, N. N. Kartsev, B. V. Eruslanov, M. E. Kanashenko, and N. K. Fursova. "Development of candidate vaccines against infection caused by shiga-toxin producing Escherichia coli. Part 2." Bacteriology 5, no. 3 (2020): 47–59. http://dx.doi.org/10.20953/2500-1027-2020-3-47-59.

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Prevention and treatment of hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS) caused by Shiga-toxin producing Escherichia coli (STEC) continues to be a public health concern. The main reason for the problem is the lack of vaccines and lack of evidence for using of antibacterial etiotropic drugs to treat this infection. A promising scientific approach to create specific agents against STEC infection is the development of subunit recombinant vaccines. The analysis of experimental studies presented in this review shows that effective subunit vaccines against STEC infection can be creat
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Seo, Yu Bin, Won Suk Choi, Jacob Lee, Joon Young Song, Hee Jin Cheong, and Woo Joo Kim. "Comparison of the Immunogenicity and Safety of the Conventional Subunit, MF59-Adjuvanted, and Intradermal Influenza Vaccines in the Elderly." Clinical and Vaccine Immunology 21, no. 7 (2014): 989–96. http://dx.doi.org/10.1128/cvi.00615-13.

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ABSTRACTThe influenza vaccination is known as the most effective method for preventing influenza infection and its complications in the elderly. Conventional subunit (Agrippal S1; Novartis), MF59-adjuvanted (Fluad; Novartis), and intradermal (IDflu15; Sanofi Pasteur) influenza vaccines are widely used throughout South Korea. However, few comparative studies evaluating the safety and immunogenicity of these vaccines are available. Prior to the beginning of the 2011-2012 influenza season, 335 healthy elderly volunteers randomly received one of three seasonal trivalent influenza vaccines, the con
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Bai, Chunxiang, Lijun Zhou, Junxia Tang, et al. "Fusion Cytokines IL-7-Linker-IL-15 Promote Mycobacterium Tuberculosis Subunit Vaccine to Induce Central Memory like T Cell-Mediated Immunity." Vaccines 8, no. 4 (2020): 715. http://dx.doi.org/10.3390/vaccines8040715.

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Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis), is among the most serious infectious diseases worldwide. Adjuvanted protein subunit vaccines have been demonstrated as a kind of promising novel vaccine. This study proposed to investigate whether cytokines interliukine-7 (IL-7) and interliukine-15 (IL-15) help TB subunit vaccines induce long-term cell-mediated immune responses, which are required for vaccination against TB. In this study, mice were immunized with the M. tuberculosis protein subunit vaccines combined with adnovirus-mediated cytokines IL-7, IL-15, IL-7-I
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BURNETTE, W. "Recombinant subunit vaccines." Current Opinion in Biotechnology 2, no. 6 (1991): 882–92. http://dx.doi.org/10.1016/s0958-1669(05)80126-0.

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Neal Burnette, W. "Recombinant subunit vaccines." Current Biology 2, no. 2 (1992): 102. http://dx.doi.org/10.1016/0960-9822(92)90232-y.

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Isaacs, David. "Viral subunit vaccines." Lancet 337, no. 8751 (1991): 1223–24. http://dx.doi.org/10.1016/0140-6736(91)92893-7.

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Van der Weken, Hans, Eric Cox, and Bert Devriendt. "Advances in Oral Subunit Vaccine Design." Vaccines 9, no. 1 (2020): 1. http://dx.doi.org/10.3390/vaccines9010001.

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Many pathogens invade the host at the intestinal surface. To protect against these enteropathogens, the induction of intestinal secretory IgA (SIgA) responses is paramount. While systemic vaccination provides strong systemic immune responses, oral vaccination is the most efficient way to trigger protective SIgA responses. However, the development of oral vaccines, especially oral subunit vaccines, is challenging due to mechanisms inherent to the gut. Oral vaccines need to survive the harsh environment in the gastrointestinal tract, characterized by low pH and intestinal proteases and need to r
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Hanke, Tomáš, Andrew J. McMichael, and Lucy Dorrell. "Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction." Journal of General Virology 88, no. 1 (2007): 1–12. http://dx.doi.org/10.1099/vir.0.82493-0.

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Candidate human immunodeficiency virus type 1 (HIV-1) vaccines focusing on T-cell induction, constructed as pTHr.HIVA DNA and modified vaccinia virus Ankara (MVA).HIVA, were delivered in a heterologous prime–boost regimen. The vaccines were tested in several hundred healthy or HIV-1-infected volunteers in Europe and Africa. Whilst larger trials of hundreds of volunteers suggested induction of HIV-1-specific T-cell responses in <15 % of healthy vaccinees, a series of small, rapid trials in 12–24 volunteers at a time with a more in-depth analysis of vaccine-elicited T-cell responses proved to
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Dissertations / Theses on the topic "Subunit vaccines"

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Pinitkiatisakul, Sunan. "Recombinant subunit vaccines against Neospora caninum /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/200740.pdf.

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Andersson, Christin. "Production and delivery of recombinant subunit vaccines." Doctoral thesis, KTH, Biotechnology, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3027.

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<p>Recombinant strategies are today dominating in thedevelopment of modern subunit vaccines. This thesis describesstrategies for the production and recovery of protein subunitimmunogens, and how genetic design of the expression vectorscan be used to adapt the immunogens for incorporation intoadjuvant systems. In addition, different strategies fordelivery of subunit vaccines by RNA or DNA immunization havebeen investigated.</p><p>Attempts to create general production strategies forrecombinant protein immunogens in such a way that these areadapted for association with an adjuvant formulation wer
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Yang, Jyh-Chyang. "Liposome-based subunit and DNA hepatitis B vaccines." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367733.

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Heffernan, Michael John. "Biodegradable polymeric delivery systems for protein subunit vaccines." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/24787.

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Thesis (Ph.D.)--Biomedical Engineering, Georgia Institute of Technology, 2008.<br>Committee Chair: Dr. Niren Murthy; Committee Member: Dr. Carson Meredith; Committee Member: Dr. Julia Babensee; Committee Member: Dr. Mark Prausnitz; Committee Member: Dr. Ravi Bellamkonda.
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Wong, Yim-ping. "Development of a subunit vaccine against foot-and-mouth disease virus /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21080161.

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Liljeqvist, Sissela. "Recombinant subunit vaccines : protein immunogens, live bacteria and nucleic acids /." Stockholm : Tekniska högsk, 1998. http://www.lib.kth.se/abs98/lilj0520.pdf.

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com, movahedi ar@gmail, and Abdolreza Movahedi. "A reverse vaccinology approach to identifying subunit proteins for use in vaccines against Brachyspira pilosicoli infections in humans and animals." Murdoch University, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20090318.140633.

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The anaerobic intestinal spirochaete Brachyspira pilosicoli is the causative agent of “intestinal spirochaetosis” (IS), a disease of humans and a number of animal species. IS has been reported in adults and children worldwide but the prevalence in people living in poor hygienic conditions, indigenous populations, homosexual males, and in immunocompromised people is much higher than in other populations. IS is also widespread in pigs and chickens, and causes significant economic impact in the associated industries. To date attempts to develop a vaccine against B. pilosicoli to protect humans an
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Young, Natalie Jane. "Bovine Viral Diarrhoea Virus Subunit Vaccines : Contribution of Non-Structural Proteins." Thesis, Royal Veterinary College (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498686.

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Peagram, Rebecca Elizabeth. "Emulsion formulations as delivery systems for soluble protein subunit viral vaccines." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363615.

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Zmolek, Andrew Charles. "Controlled release microneedle technologies for the enhanced immunogenicity of subunit vaccines." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/115019.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2017.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 105-113).<br>The poor efficacy of subunit protein vaccines, which typically consist of a protein antigen and a molecular adjuvant, has recently been improved by completing multiple injections of the vaccine with an exponential dosing profile over time. The hypothesis is that as viruses replicate in a host organism, they shed exponentially increasing quantities of pathogen associated molecular patterns (PAMPs) and
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Books on the topic "Subunit vaccines"

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Foged, Camilla. Subunit vaccine delivery. Edited by Rades Thomas author, Perrie Yvonne author, and Hook Sarah author. Springer, 2015.

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Flower, Darren R., and Yvonne Perrie, eds. Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-5070-2.

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Leong, JoAnn Ching. Evaluation of a subunit vaccine to infectious hematopoietic necrosis virus: Annual report 1986. U.S. Dept. of Energy, Bonneville Power Administration, Division of Fish & Wildlife, 1986.

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Leong, JoAnn Ching. Evaluation of a subunit vaccine to infectious hematopoietic necrosis virus: Final project report. U.S. Dept. of Energy, Bonneville Power Administration, Division of Fish & Wildlife, 1991.

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Leong, JoAnn Ching. Evaluation of a subunit vaccine to infectious hematopoietic necrosis (IHN) virus: Annual report FY 1984. U.S. Dept. of Energy, Bonneville Power Administration, Division of Fish & Wildlife, 1985.

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Leong, JoAnn Ching. Evaluation of a subunit vaccine to infectious hematopoietic necrosis virus: Annual report July 31, 1989 to September 30, 1990. U.S. Dept. of Energy, Bonneville Power Administration, Division of Fish & Wildlife, 1990.

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Leong, JoAnn Ching. Evaluation of a subunit vaccine to infectious hematopoietic necrosis virus: Annual report July 31, 1988 to September 30, 1989. U.S. Dept. of Energy, Bonneville Power Administration, Division of Fish & Wildlife, 1989.

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Foged, Camilla, Thomas Rades, Yvonne Perrie, and Sarah Hook, eds. Subunit Vaccine Delivery. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1417-3.

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Binnington-Boyd, Beth A. Studies to determine the vaccine potential of the B-subunit of Shiga-like toxin 1 and its peptide fragments. National Library of Canada = Bibliothèque nationale du Canada, 1992.

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Flower, Darren R., and Yvonne Perrie. Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer, 2012.

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Book chapters on the topic "Subunit vaccines"

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Conner, Margaret E., S. E. Crawford, C. Barone, et al. "Rotavirus subunit vaccines." In Viral Gastroenteritis. Springer Vienna, 1996. http://dx.doi.org/10.1007/978-3-7091-6553-9_21.

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Martinez-Becerra, Francisco J., Olivia Arizmendi, Jamie C. Greenwood, and Wendy L. Picking. "Development of Subunit Vaccines Against Shigellosis: An Update." In Molecular Vaccines. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1419-3_10.

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Olive, Colleen. "Development of Subunit Vaccines for Group A Streptococcus." In Molecular Vaccines. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1419-3_11.

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Ewasyshyn, M., and Michel Klein. "Development of Subunit Paramyxoviridae Vaccines." In Modern Vaccinology. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-1450-7_15.

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Douglas, Alexander D. "Subunit Blood-Stage Malaria Vaccines." In Malaria. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-45210-4_11.

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Tonnis, Wouter F., Anke L. W. Huckriede, Wouter L. J. Hinrichs, and Henderik W. Frijlink. "Pulmonary Administration of Subunit Vaccines." In Advances in Delivery Science and Technology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1417-3_16.

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Lowry, Deborah. "Vaginal Delivery of Subunit Vaccines." In Advances in Delivery Science and Technology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1417-3_17.

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Lecocq, J. P., M. P. Kieny, P. Curtis, and R. Lathe. "Genetically Engineered Rabies Subunit Vaccines." In Rabies in the Tropics. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70060-6_44.

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Jin, Tom, and Eric Tsao. "Powder Vaccines for Pulmonary Delivery." In Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5070-2_14.

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Skea, Danna L., and Brian H. Barber. "Immunotargeting as an Adjuvant-Independent Subunit Vaccine Design Option." In New Generation Vaccines. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2948-4_10.

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Conference papers on the topic "Subunit vaccines"

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Krishnakumar, D., and K. S. Jaganathan. "Development of nasal HPV vaccine formulations." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685403.

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Cervical cancer is the second most cancer in women worldwide with over 500000 new cases and 275000 deaths being registered every year. With nearly 73000 women dying every year, India now tops the world in cervical cancer deaths. India represents 26.4% of all women dying of cervical cancer globally. Cervical cancer estimated to be responsible for about 5% of human cancers worldwide. Currently available vaccines may not provide complete protection against all HPV types as the protection is primarily type specific. Furthermore, the available vaccines are delivered via intramuscular route and requ
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Patarroyo, Manuel Elkin. "Different strategies towards the design of a synthetic subunit malaria vaccine." In Future Aspect in Peptide Chemistry - Ringberg Conference. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199901108.

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Layton, S. L., and M. F. Jabif. "Development and evaluation of a novel orally administered subunit vaccine to control foodborne pathogens." In Safe Pork 2015: Epidemiology and control of hazards in pork production chain. Iowa State University, Digital Press, 2017. http://dx.doi.org/10.31274/safepork-180809-390.

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Quessy, Sylvain, A. Desautels, R. E. Prud'homme, and Ann Letellier. "Protection of pigs against experimental Salmonella Typhimurium infection by use of a single dose subunit slow delivery vaccine." In First International Symposium on the Ecology of Salmonella in Pork Production. Iowa State University, Digital Press, 2007. http://dx.doi.org/10.31274/safepork-180809-91.

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Fernandes, André, Luciane Gaspar, Renata Pereira, et al. "Plant-produced YFE-1T subunit vaccine against Yellow Fever induces humoral response in captive golden-headed lion tamarin (Leontopithecus chrysomelas)." In IV International Symposium on Immunobiologicals & VII Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2019. http://dx.doi.org/10.35259/isi.sact.2019_32549.

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Vlachantoni, I., S. Ascough, R. Grimaldi, K. Leenhouts, C. Chiu, and P. Openshaw. "S68 Phase 1 trial of an intranasal respiratory syncytial virus (rsv) subunit candidate vaccine: safety results from the muc-syngem study." In British Thoracic Society Winter Meeting 2017, QEII Centre Broad Sanctuary Westminster London SW1P 3EE, 6 to 8 December 2017, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2017. http://dx.doi.org/10.1136/thoraxjnl-2017-210983.74.

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Reports on the topic "Subunit vaccines"

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Leong, JoAnn Ching. Evaluation of a Subunit Vaccine to Infectious Hematopoietic Necrosis Virus, 1986 Annual Report. Office of Scientific and Technical Information (OSTI), 1986. http://dx.doi.org/10.2172/758122.

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Leong, JoAnn Ching. Evaluation of a Subunit Vaccine to Infectious Hematopoietic Necrosis (IHN) Virus, 1984 FY Annual Report. Office of Scientific and Technical Information (OSTI), 1985. http://dx.doi.org/10.2172/758121.

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Leong, JoAnn Ching. Evaluation of a Subunit Vaccine to Infectious Hematopoietic Necrosis Virus, July 31, 1988 to September 20, 1989 Annual Report. Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/758123.

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Leong, JoAnn Ching. Evaluation of a Subunit Vaccine to Infectious Hematopoietic Necrosis Virus, July 31, 1989 to September 30, 1990, Annual Report. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/758124.

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Fischer, N. O. Nanolipoprotein Particles (NLPs) as Versatile Vaccine Platforms for Co-delivery of Multiple Adjuvants with Subunit Antigens from Burkholderia spp. and F. tularensis - Technical Report. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1179402.

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Fischer, N. O. Nanolipoprotein Particles (NLPs) as Versatile Vaccine Platforms for Co-delivery of Multiple Adjuvants with Subunit Antigens from Burkholderia spp. and F. tularensis - Technical Report. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1179410.

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Fischer, N. O. Nanolipoprotein Particles (NLPs) as Versatile Vaccine Platforms for Co-delivery of Multiple Adjuvants with Subunit Antigens from Burkholderia spp. and F. tularensis - Annual Technical Report. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1241947.

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