Journal articles on the topic 'Suchá sorpce'

Recent literature in second language acquisition shows that syntax-driven structures give way to successful modal interpretation and morphological production, while discourse-dependent environments do not (Sorace, 2005; Tsimpli & Sorace, 2006, Borganovo, Bruhn de Garavito, & Prévost, 2008; Iverson, Kempchinsky, & Rothman, 2008). It has also been suggested that discourse-dependent environments involve both structural and pragmatic knowledge of L2, which intersect at the syntax-discourse interface (Sorace, 2005; Iverson, Kempchinsky, & Rothman, 2008), thereby requiring a multi-layered understanding of the target language. The present study contributes to this line of research by further examining morphological variability (Prévost & White, 2000; Sorace, 2000; Sorace, 2005; Iverson, Kempchinsky, & Rothman, 2008; Slabakova, 2009) in L2 acquisition at the morphosyntactic-semantic interface, following the work of Borganovo, Bruhn de Garavito, & Prévost (2008). The results of our study reveal that learners, even at advanced stages of acquisition, perform poorly in epistemic environments where syntax and discourse intersect. In such environments, there appears to be an interaction with pragmatics (cf. Iverson, Kempchinsky, & Rothman, 2008) that causes learners to opt for the indicative mood, even when the subjunctive is prescriptively required. Unlike deontic modality, which is essentially syntax-driven, epistemic modality requires structural knowledge, as well as knowledge from other domains (Sorace, 2005). Our study reveals that learners at all levels of instruction performed better in “purely syntactic” environments of deontic modality than in pragmatically challenging epistemic environments.

A set of relationships between parameters of the Dunham and Murrell-Sorbie potential energy function is developed. By employing Taylor series expansion and comparison of terms arranged in increasing order of bond length, a set of Dunham coefficients is obtained as functions of Murrell- Sorbie parameters. The conversion functions reveal the importance of factorials in extracting Dunham coefficients from Murrell-Sorbie parameters. Plots of both functions, based on parameters of the latter, reveal good correlation near the equilibrium bond length for a group of diatomic molecules. Potential function relations, such as that shown in this paper, are useful when the preferred/reliable data is based on a potential function different from that adopted in available computational software.

Extensive exposure of zinc(II) ions may cause eminent health problems, such as stomach cramps, skin irritations, vomiting, anaemia, a damage of pancreas, the disturbance of protein metabolism, and also respiratory disorders. Due to these problems, zinc(II) concentration in drinking water should be controlled. Peat is one of the material that can be used to minimize zinc(II) ions from a solution. The study was done to determine the performance and sorption equilibrium of zinc ions onto oligothropic peat particles. The sorption experiments were conducted in a several batch reactor of erlenmeyer flask at a constant temperature of 26 ± 3 oC. The initial zinc ions concentration and pH were varied. Response variable was residual zinc concentration that was measured spectrophotometrically. Experimental data show that the optimum sorption efficiency was about 90% for the initial zinc(II) concentration of 50 mg/L. Sorption equilibrium can be represented by the Freundlich and Langmuir isotherm models. For the initial pH of 6, the optimum sorption capacity, qo was 3,736 mg/g, and the Freundlich’s characteristic constant, Kf was about 0,342 L/g. Key words : peat, sorption equilibrium, sorption isotherm, zinc(II) ions AbstrakPaparan ion seng(II) pada kadar tertentu dapat menyebabkan berbagai masalah kesehatan seperti kram perut, iritasi kulit, batuk, anemia, kerusakan pankreas, gangguan metabolisme protein, penyumbatan pembuluh darah, hingga kerusakan sistem pernafasan. Karena itu, seng(II) termasuk kategori unsur yang harus dibatasi konsentrasinya dalam air minum. Gambut adalah salah satu material yang dapat digunakan untuk mengurangi ion seng dari larutan. Penelitian ini bertujuan untuk mempelajari performansi dan kesetimbangan sorpsi ion seng(II) pada partikel gambut oligotropik Indonesia. Penelitian dilakukan secara batch di dalam sejumlah labu erlenmeyer pada temperatur konstan 26 ± 3 oC. Eksperimen dilakukan dalam beberapa variasi konsentrasi awal ion seng dan pH. Data primer adalah konsentrasi residual seng dalam larutan yang diukur secara spektrofotometrik. Hasil penelitian menunjukkan bahwa efisiensi optimum sorpsi mencapai lebih dari 90% untuk konsentrasi awal seng 50 mg/L. Kesetimbangan sorpsi logam seng(II) pada partikel gambut dapat direpresentasikan dengan baik oleh model isoterm Freundlich dan Langmuir. Untuk rentang pH awal 6, nilai kapasitas sorpsi optimum, qo adalah 3,736 mg/g, sedangkan nilai konstanta karakteristik Freundlich, Kf adalah 0,342 L/g. Kata kunci : efisiensi sorpsi, gambut, isoterm sorpsi, ion seng(II)

The application of spatiotemporal (ST) analytics to integrated data from major sources such as the World Bank, United Nations, and dozens of others holds tremendous potential for shedding new light on the evolution of cultural, health, economic, and geopolitical landscapes on a global level. Realizing this potential first requires an ST data model that addresses challenges in properly merging data from multiple authors, with evolving ontological perspectives, semantical differences, and changing attributes, as well as content that is textual, numeric, categorical, and hierarchical. Equally challenging is the development of analytical and visualization approaches that provide a serious exploration of this integrated data while remaining accessible to practitioners with varied backgrounds. The WSTAMP project at Oak Ridge National Laboratory has yielded two major results in addressing these challenges: 1) development of the WSTAMP database, a significant advance in ST data modeling that integrates 10,000+ attributes covering over 200 nation states spanning over 50 years from over 30 major sources and 2) a novel online ST exploratory and analysis tool providing an array of modern statistical and visualization techniques for analyzing these data temporally, spatially, and spatiotemporally under a standard analytic workflow. We discuss the status of this work and report on major findings.

AbstractSome key physical processes that impact the evolution of Earth's atmosphere on time-scale from days to millennia, such as the EUV emissions, are determined by the solar magnetic field. However, observations of the solar spectral irradiance are restricted to the last few solar cycles and are subject to large uncertainties. We present a physics-based model to reconstruct short-term solar spectral irradiance (SSI) variability. The coronal magnetic field is estimated to employ the Potential Field Source Surface extrapolation (PFSS) based on observational synoptic charts and magnetic flux transport model. The emission is estimated to employ the CHIANTI atomic database 8.0. The performance of the model is compared to the emission observed by TIMED/SORCE.

Maytenus ilicifolia Mart. ex Reissek é conhecida, popularmente, como "Espinheira-santa", pertence à família Celastraceae, e é encontrada predominantemente na Região Sul do Brasil. Tradicionalmente é utilizada pela população por possuir eficientes propriedades farmacológicas contra afecções gástricas e várias outras enfermidades. Há uma acentuada semelhança morfológica entre outras espécies de Maytenus Mol. e outras taxas como Zollernia ilicifolia (Brong.) Vogel (Fabaceae) e Sorocea bonplandii (Baill.) W.C. Burger & Lanj. & Wess. Boer (Moraceae), principalmente, por apresentarem folhas coriáceas, com margens espinescentes, levando-as a serem confundidas e comercializadas erroneamente em mercados populares de ervas medicinais. Foram adquiridas amostras comerciais de 11 pontos de venda, nos municípios do Rio de Janeiro, Duque de Caxias, Pavuna e Nova Iguaçu, no Estado do Rio de Janeiro, Brasil. Observou-se que todas as amostras avaliadas pertencem ao gênero Sorocea A. St.-Hil. (Moraceae). Este resultado aponta para a necessidade de certificação desse tipo de produto. Palavras-chave: Maytenus ilicifolia. Plantas Medicinais. Afecções Gástricas. AbstractMaytenus ilicifolia Mart. ex Reissek is popularly known as "Espinheira-santa". This specie belongs to the Celastraceae family and it’s found predominantly in southern Brazil. The traditional use of this plant by local people is mainly due to its efficient pharmacological properties against stomach disorders and many other diseases. There is a morphological similarity on the leathery leaves with spiny margins between Maytenus ilicifolia and other species Maytenus Mol. and other taxa such as Zollernia ilicifolia (Brong.) Vogel (Fabaceae) and Sorocea bonplandii (Baill.) WC Burger & Lanj. & Wess. Boer (Moraceae). This similarity has caused confusion and sold mistankenly in popular markets of medicinal herbs. Commercial samples from 11 stores were purchased in the cities of Rio de Janeiro, Duque de Caxias, Pavuna and Nova Iguaçu, in the state of Rio de Janeiro, Brazil. It was observed that all samples belong to the genus Sorocea A. St.-Hil. (Moraceae). This result points to the need for certification of this type of product. Keywords: Celastraceae Maytenus. Medicinal Plants. Stomach Disorders.

Abstract. Although exit polling has not been used to study Canadian elections before, such polls have methodological features that make them a potentially useful complement to data collected through more conventional designs. This paper reports on an experiment with exit polling in one constituency in the 2003 Ontario provincial election. Using student volunteers, a research team at Wilfrid Laurier University conducted an exit poll in the bellwether constituency of Kitchener Centre to assess the feasibility of mounting this kind of study on a broader scale. The experiment was successful in a number of respects. It produced a sample of 653 voters that broadly reflected the partisan character of the constituency, and which can hence be used to shed light on patterns of vote-switching and voter motivations in that constituency. It also yielded insights about best practices in mounting an exit poll in the Ontario context, as well as about the potential for using wireless communication devices to transmit respondent data from the field. The researchers conclude that exit polling on a limited basis (selected constituencies) is feasible, but the costs and logistics associated with this methodology make a province-wide or country-wide study unsupportable at present.Résumé. Bien que les sondages “sortie des urnes” n'aient pas été utilisés jusqu'ici dans l'étude des élections au Canada, de tels sondages possèdent certaines caractéristiques qui en font un complément potentiellement très utile des méthodes plus traditionnelles de cueillette des données. Cet article rend compte d'un sondage “sortie des urnes” expérimental effectué dans une circonscription lors de l'élection provinciale de 2003 en Ontario. Utilisant des bénévoles étudiants, une équipe de recherche de l'Université Wilfrid Laurier a conduit un sondage “sortie des urnes” à Kitchener Centre, une circonscription indicatrice de tendance, afin de déterminer la faisabilité de ce type d'étude au niveau fédéral. L'expérience a réussi à plusieurs égards. Elle a fourni un échantillon de 653 électeurs qui reflétaient en gros le caractère partisan de la circonscription, ce qui a rendu possible l'étude des motivations des électeurs et des revirements de vote dans la région. L'expérience a aussi fourni des renseignements sur les pratiques exemplaires concernant l'utilisation des sondages “sortie des urnes” au niveau provincial, ainsi que sur la possibilité d'employer des techniques de communication sans fil pour transmettre les données recueillies des répondants. Les chercheurs ont conclu que les sondages “sortie des urnes” sont réalisables dans un cadre restreint, dans certaines circonscriptions sélectionnées, mais que les coûts et la logistique nécessités par cette méthodologie la rendent actuellement impraticable pour une étude à l'échelle provinciale ou nationale.

Pepper (Capsicum annuum) is one of the major vegetable species in the world, and Serbia as well. The pepper assortment of the Institute of Field and Vegetable Crops includes varieties of different fruit type such as the bell, conical, kapia, elongated, pepperoni and tomato-shaped peppers. However, in the assortment of the Institute, there is no variety of sweet pepper with conical and hanging fruits. Because of that, we wanted to develop a new pepper variety with this fruit type and offer it to the market. Selected lines from one of the crossbreeding combinations were grown in the open field and the greenhouse area by the pedigree method in the period 2012-2017. Based on the phenotype, the most vital plants that had the desired characteristics of the fruit were selected. During the many years of breeding, a new pepper variety NS Prva was obtained. NS Prva has been registered in the Republic of Serbia in 2019 and from that period it has been on the National variety list. The fruits of this variety are about 150 g, have one peak, grow hanging on the plant, with light yellow colour in technological maturity, and red in full maturity. A new pepper variety NS Prva is recommended for growing in a greenhouse where it gives uniform fruits suitable for the market in all maturity stages. It can also be recommended for growing in the open field where it gives slightly longer fruits. NS Prva showed good storage ability three weeks after harvest since it had the smallest reduction in fruit weight during storage in a cold chamber

In this paper we present an analysis of Spanish heritage speakers’ oral production of gender agreement outside the DP as an innovative source of support for the Interface Hypothesis (Sorace & Filiaci 2006). We demonstrate that, besides commonly known factors such as the gender, animacy and morphology of the antecedent, the interface domain in which gender agreement takes place also seems to play a role in how accurately heritage speakers apply gender agreement. Pronominal reference, located at the external syntax-discourse interface, turns out to be more problematic than adjectival predication, which pertains to the internal morpho-syntax interface. Furthermore, we discuss the possibility that, besides the amount of input heritage speakers receive, the quality of this input may also play a role in their gender agreement accuracy, given that the heritage speakers’ error pattern with respect to linguistic factors is very similar to that of first generation immigrants.

I describe research done in collaboration with J. Sorce showing that one cannot over-charge and/or over-spin an initially slightly nonextremal Kerr–Newman black hole via the type of gedanken experiments proposed by Hubeny and others, assuming that the nonelectromagnetic stress-energy tensor of the matter entering the black hole satisfies the null energy condition. Analysis of such gedanken experiments requires that we calculate all effects on the final mass of the black hole that are second-order in the charge and the angular momentum carried into the black hole. We do so using Lagrangian methods, and our formula for the second-order correction to mass, [Formula: see text], is obtained by generalizing the canonical energy analysis of Hollands and Wald to the Einstein–Maxwell case. Our formula for [Formula: see text] automatically includes all self-force and finite size effects.

This article considers the acquisition of three English syntax–discourse interface constructions: Topicalization, Focus Fronting and Left Dislocation. We use data from Basque–Spanish bilinguals learning English as a third language (L3) as a test case for the Interface Hypothesis (IH, Sorace, 2011). The IH has made specific predictions about second language (L2) acquisition and such predictions can be extrapolated to L3 on the basis of interface delay explanations. Thirty contexts and embedded test sentences with and without pronouns were used; participants had to rate the acceptability of each audio stimulus sentence in the context on a seven-point scale. We tested Basque–Spanish bilinguals dominant in Basque (n = 23), Basque–Spanish bilinguals dominant in Spanish (n = 24), Spanish L2 English learners (n = 39) as well as native English speakers (n = 24). Findings provide evidence against current L3 acquisition models and potential arguments for both cumulative enhancement as well as cumulative inhibition as possible processes in L3 acquisition.

This paper investigates the knowledge of two unaccusative diagnostics in ­Italian, auxiliary selection and ne cliticisation, in child L2 grammars of L1 Croatian speakers. The two phenomena are not instantiated in Croatian. Following ­Sorace (2000), it is assumed in the paper that the lexical-semantic aspect of these phenomena is characterised by gradience that can be captured by the Auxiliary Selection Hierarchy. Findings are reported of an experimental study in which highly proficient child L2 learners and their monolingual peers rated the acceptability of two Italian auxiliaries and ne-cliticisation with different lexical-semantic classes of intransitives by using the Magnitude Estimation technique. The learners’ judgements largely converged on those of the native speakers, suggesting that the two phenomena had been acquired in the L2. Such findings support the hypothesis predicting complete L2 acquisition of properties pertaining to an interface between two domains within the language factory (the so-called internal interfaces), in this case syntax and the lexicon.

Recent proposals argue that interface areas such as syntax/semantics and syntax/pragmatics are particularly difficult for adult learners, in comparison to purely syntactic phenomena (Sorace 2003, 2004). In contrast, other research shows that L2 learners are able to acquire target representations even when the interpretation is not readily available in the input (Borgonovo, Bruhn de Garavito and Prévost 2005, Dekydtspotter and Sprouse 2001). In this paper we add to the growing literature on the acquisition of interpretational properties by showing that adult L2 learners can acquire knowledge of the syntactic correlates of the semantic notion of specificity in constructions involving topicalisation and null objects in Spanish. The learners’ first language (L1) is Brazilian Portuguese, where specificity does not play the role in these constructions that it plays in Spanish. Results show that learners can go beyond their L1 with respect to the acquisition of interface phenomena, suggesting that native-like grammars are attainable in L2 acquisition.

Abstract. The bolometric oscillation sensor (BOS) is a broadband radiation measurement instrument onboard the PICARD satellite that has been active between 2010 and 2014. The main detector is a thermistor attached black coated surface, which was permanently exposed to space without any optical and aperture accessories. The temperature measurements are used within a transfer function to determine variations in incoming solar irradiance as well as the terrestrial radiation. In the present article, the measurement principle of BOS and its transfer function are presented. The performance of the instrument is discussed based on laboratory experiments and space observations from the PICARD satellite. The comparison of the short term variation of Total Solar Irradiance (TSI) with absolute radiometers such as VIRGO/SOHO and TIM/SORCE over the same period of time, suggests that BOS is a relatively much simpler but very effective sensor to monitor electromagnetic radiation variations from visible to infrared wavelengths.

Abstract This article presents the results of research on the Cd2+ ions sorption from model aqueous solutions on sunflower hulls, walnut shells and plum stones. The effect of various factors, such as mass of the natural sorbent, the pH, the time and the temperature was studied. The process of Cd2+ ions sorption on studied sorbents was described by the Langmuir model. The best sorption capacity has been achieved for sunflower hulls. The maximum sorption capacity for this material was 19.93 mg/g.

Molecular stratification of disease based on expression levels of sets of genes can help guide therapeutic decisions if such classifications can be shown to be stable against variations in sample source and data perturbation. Classifications inferred from one set of samples in one lab should be able to consistently stratify a different set of samples in another lab. We present a method for assessing such stability and apply it to the breast cancer (BCA) datasets of Sorlie et al. 2003 and Ma et al. 2003. We find that within the now commonly accepted BCA categories identified by Sorlie et al. Luminal A and Basal are robust, but Luminal B and ERBB2+ are not. In particular, 36% of the samples identified as Luminal B and 55% identified as ERBB2+ cannot be assigned an accurate category because the classification is sensitive to data perturbation. We identify a “core cluster” of samples for each category, and from these we determine “patterns” of gene expression that distinguish the core clusters from each other. We find that the best markers for Luminal A and Basal are (ESR1, LIV1, GATA-3) and (CCNE1, LAD1, KRT5), respectively. Pathways enriched in the patterns regulate apoptosis, tissue remodeling and the immune response. We use a different dataset (Ma et al. 2003) to test the accuracy with which samples can be allocated to the four disease subtypes. We find, as expected, that the classification of samples identified as Luminal A and Basal is robust but classification into the other two subtypes is not.

Abstract. The Bolometric Oscillation Sensor (BOS) is a broadband radiation measurement instrument onboard the PICARD satellite that was active between 2010 and 2014. The main detector is a thermistor attached black coated surface, which was permanently exposed to space without any optical and aperture accessories. The temperature measurements are used within a transfer function to determine variations in incoming solar irradiance as well as the terrestrial radiation. In the present article, the measurement principle of the BOS and its transfer function are presented. The performance of the instrument is discussed based on laboratory experiments and space observations from the PICARD satellite. The comparison of the short-term variation of total solar irradiance (TSI) with absolute radiometers such as VIRGO/SOHO and TIM/SORCE over the same period of time suggests that the BOS is a relatively much simpler but very effective sensor for monitoring electromagnetic radiation variations from visible to infrared wavelengths.

When analyzing typical assault aviation combat missions, the most common objects for each aircraft actions should be identified, a preliminary estimate of their distance from the front line has to be provided, and one of the objects should be selected as the typical target for evaluating the aircraft effectiveness. A destruction of a typical target by an aircraft with a certain probability is one of the main components of the assault aviation aircraft effectiveness, but it does not fully characterize the effectiveness of the aircraft. In the course of assault aircraft combat mission accomplishment, the generally accepted approach is identification the four aircraft flight phases with a purpose of destruction a surface target. As a combat mission for assault aircraft the striking for destruction an enemy airfield or division of guided missiles can be considered. The choice of flight route and profile is related to the assessment of the enemy's actual areas of engagement to determine the line of maneuvering. The feature of devastating effect of attack ammunition is the conditional law of target destruction. For the means of destruction of a remote action the feature of devastating effect of attack ammunition is a cumulative effect of each munitions at known coordinates of impact points. For the means of destruction which are used in cluster bombs, as a result of small caliber live ammunition scattering the total area of destruction is created. The cover area for single cluster bomb is ellipse shaped. Thus, in order to evaluate the effectiveness of the assault aviation aircraft employment it is advisable to use an indicator such as the effectiveness of the aircraft in one combat sortie. Evaluation of aircraft effectiveness in one sortie consists of estimates of the probability for penetration the means of air defense, the probability of target detection, the probability of target attack, the probability of target destruction and reliability of aviation equipment. For assault aviation, the effectiveness of an aircraft in a single combat sortie has the notion of a total probability of a target destruction or a mathematical expectation of a target destruction.

We have characterized canopy geometry and light transmission by the nine dominant conifer and broad-leaved tree species of the interior cedar-hemlock (ICH) forests of northern British Columbia. Our field data were used to parameterize a spatially explicit model of light transmission through mixed-species forests. That model, a component of the forest dynamics simulator SORTIE, was developed for eastern deciduous forests, and this paper presents a test of that model in a very different ecosystem. Our results show that individual crowns of the ICH forests intercepted much more light than species of eastern deciduous forests but that the canopy as a whole allowed greater light penetration, largely because of openings between the relatively narrow, conical crowns of the western conifers. Light transmission by individual crowns was correlated with shade tolerance among the conifers (as in eastern deciduous species), but crown depth was not (in contrast with eastern species). Despite the fundamental differences in the nature of light transmission in the two ecosystems, the SORTIE light model developed for eastern deciduous forests was effective at predicting spatial variation in understory light levels in these western coniferous forests. The goodness of fit of such a simple model suggests that the most important factors regulating spatial variation in understory light levels in these forests are simply the sizes and distribution of nearby trees, and the local sky brightness distribution. Discrete canopy gaps represent a special case in which a region of the canopy is not occupied by crowns.

This investigation deals with the determination of various physico-chemical and biological parameters of surface water quality of river Noyyal and its connected ponds at Coimbatore, India. Based on their significance, the sampling locations were selected. There are five sampling locations were selected like river Noyyal at sorce (S1), Perur Lake, (S2), Ukkadam Pond (S3), Singanallur Lake (S4) and Sulur Pond (S5), and samples were collected from each locations at river Noyyal basin in and around Coimbatore district. The surface water quality index determination is prerequisite and essential. In this present work, from different methods of water quality determination, the most commonly used index of National Sanitation Foundation water quality index (NSF-WQI) has been followed. The physico-chemical and biological parameters such as dissolved oxygen, faecal coliforms counts, pH, biochemical oxygen demand, phosphate, nitrates, turbidity, and total dissolved solids were investigated. Except in Noyyal river at source (S1) all the measured parameters are showed to be very high compared to limits suggested by WHO particularly during summer season and thereby it is not suitable for public use.

In forests of eastern North America, introduced pathogens have caused widespread declines in a number of important tree species, including dominant species such as American beech (Fagus grandifolia Ehrh.). Most studies have focused on changes in forest composition and structure as a direct result of mortality caused by a pathogen. Our field studies of windthrow resistance in forests of northern New York and northern Michigan demonstrate that resistance of beech trees to windthrow is severely reduced by beech bark disease (BBD). This reduced resistance was primarily due to the increase in the probability of stem breaks of moderately and highly infected beech trees. The severity of BBD infection on individual trees has a significant negative effect on resistance to windthrow. We tested potential consequences of this for long-term composition and structure in these forests by using a simulation model, SORTIE. We found that species such as yellow birch (Betula alleghaniensis Britt.) and eastern hemlock (Tsuga canadensis (L.) Carr.) increased in basal area primarily because of the effect BBD had on the creation of new seedbed substrates. Our results highlight the indirect effects that host-specific pathogens can have on community dynamics and species coexistence in forests.

Abstract. Aerosol particles play important roles in regional air quality and global climate change. In this study, we analyzed 2 years (2011–2013) of measurements of submicron particles (6–800 nm) at a suburban site in the western Yangtze River Delta (YRD) of eastern China. The number concentrations (NCs) of particles in the nucleation, Aitken and accumulation modes were 5300 ± 5500, 8000 ± 4400, 5800 ± 3200 cm−3, respectively. The NCs of total particles are comparable to those at urban/suburban sites in other Chinese megacities, such as Beijing, but about 10 times higher than in the remote western China. Long-range and regional transport largely influenced number concentrations and size distributions of submicron particles. The highest and lowest accumulation-mode particle number concentrations were observed in air masses from the YRD and coastal regions, respectively. Continental air masses from inland brought the highest concentrations of nucleation-mode particles. New particle formation (NPF) events, apparent in 44 % of the effective measurement days, occurred frequently in all the seasons except winter. The frequency of NPF in spring, summer and autumn is much higher than other measurement sites in China. Sulfuric acid was found to be the main driver of NPF events. The particle formation rate was the highest in spring (3.6 ± 2.4 cm−3 s−1), whereas the particle growth rate had the highest values in summer (12.8 ± 4.4 nm h−1). The formation rate was typically high in relatively clean air masses, whereas the growth rate tended to be high in the polluted YRD air masses. The frequency of NPF events and the particle growth rates showed a strong year-to-year difference. In the summer of 2013, associated with a multi-week heat wave and strong photochemical processes, NPF events occurred with larger frequency and higher growth rates compared with the same period in 2012. The difference in the location and strength of the subtropical high pressure system, which influences the air mass transport pathways and solar radiation, seems to be the cause for year-to-year differences. This study reports, up to now, the longest continuous measurement records of submicron particles in eastern China and helps to achieve a comprehensive understanding of the main factors controlling the seasonal and year-to-year variation of the aerosol size distribution and NPF in this region.

Short-pulse welding parameters for resistance spot welding (RSW) of aluminum alloy AA6016-T4 using mediumfrequency direct current (MFDC) systems were developed to reduce the heat input required for nugget formation. Optimization of current and time parameters is critical during RSW of aluminum alloys for reducing energy requirements and avoiding weld imperfections, such as solidification cracking and expulsion, while maintaining weld quality, particularly given the high electrical and thermal conductivities of the materials. The welding time and the applied current level of the current pulse were varied systematically for thin sheets (1 mm or 0.04 in.) of AA6016-T4. The quality of the welds was evaluated by pull-out testing, ultrasound testing, and metallography techniques. Simulations of the same welding processes were performed with the finite element-based SORPAS® software. The results showed short-pulse MFDC RSW can reduce the energy required for sound welds in this alloy without requiring an increase in welding current. The simulations and experiments also showed the welding process had distinct weld nugget nucleation and growth phases.

William C. Burke, an African American emigrant in Liberia, wrote the following to an acquaintance in the United States on 23 September 1861: This must be the severest affliction that have visited the people of the United States and must be a sorce [sic] of great inconvenience and suffering and although we are separated from the seane [sic] by the Atlantic yet we feel sadly the effects of it in this country. The Steavens not coming out as usual was a great disappointment and loss to many in this country.Burke's lamentation about the impact of the American Civil War on the distant Atlantic shores of Africa underscores a problem—and opportunity—in Liberian historiography. Burke's nineteenth-century world extended past the distinct national boundaries that separated the United States and Liberia. Geographically, this was the vast littoral of the four continents—Africa, Europe, North America, and South America—abutting the Atlantic Ocean. But the Atlantic world, as historians now dubbed this sprawling transnational zone, was much more extensive. Societies near and faraway were also drawn into the web of socioeconomic activities in the basin. The creation of the Atlantic world spanned almost four centuries, from the late fifteenth to the waning decades of the nineteenth century. In this period, an unprecedented multitude of migrants crisscrossed the Atlantic creating a vast network. For example, by the nineteenth century, regular transatlantic packages such as the Mary Caroline Stevens whose delay Burke called “a great disappointment,” transported passengers, provisions, and dispatches between the United States and Liberia.

This paper presents the process of real estate reallocation as a mass cadastral subdivision process of agrarian communities’ customary rights. The agricultural communities have existed for centuries and have been jointly owning and using the common land. Such gatherings were developed mainly due to the unique requirements deriving from land use and relief characteristics, such as joint forest management on mountain slopes. The main objective of this research has been to analyse the process of real estate subdivision, which has its legal background in Slovenian legislation. In this paper, the process of cadastral subdivision of land owned by agricultural communities is presented as a mass cadastral land subdivision process: from preparatory work to the new geometric structure of the common land. The cadastral, organisational, and engineering role of the chartered surveying engineer and the surveying company is examined. An aim of the paper is, inter alia, to develop a conceptual model of the process that will serve as a basis for optimisation, for a more just and more efficient distribution of assets among community members. The course of the individual steps of the community established land subdivision is shown with unified modelling language (UML) activity diagrams. As a case study, we have considered the subdivision of the property of the agricultural community of Zgornja Sorica in Slovenia.

This study deals with an aircraft-to-target assignment (ATA) problem considering the modern air operation environment, such as the strike package concept, multiple targets for a sortie, and the strike packages’ survivability. For the ATA problem, this study introduces a novel mathematical model in which a heterogeneous vehicle routing problem (HVRP) and a weapon-to-target assignment (WTA) problem are conceptually integrated. The HVRP generates the flight routes for strike packages because this study confirms that the survivability of a strike package depends on the path, and the WTA problem evaluates the likelihood of successful target destruction of assigned weapons. Although the first version of the model is developed as a mixed-integer nonlinear programming (MINLP) model, this study attempts to convert it to a mixed-integer linear programming (MILP) model using the logarithmic transformation and piecewise linear approximation methods. For an ATA problem, this activity could provide an opportunity to use the excellent existing algorithms for searching the optimal solution of LP models. To maximize the operational effectiveness, the MILP model simultaneously determines the following for each strike package: (a) composition type, (b) targets, (c) flight route, (d) types, and (e) quantity of weapons for each target.

Evaluation of five inner carriers and Bacillus subtilis formulation to control banded leaf and sheath blight (Rhizoctonia solani Kuhn). One alternative control method against plant pathogens is the use of antagonistic microorganisms, such as Bacillus subtilis. The use of the antagonistic bacteria on corn especially in Indonesia is still lack. The objective of this research was to evaluate some inner carrier and to make formulated antagonistic B. subtilis to be used as biological control agents on corn diseases. This research consists of laboratory and greenhouse activities. The laboratory activities consist of B. subtilis biomass production, formulation of B. subtilis, and evaluation of five types of inner carrier. In the greenhouse, testing the formulation B. subtilis with talc as an inner carrier, which is compared with the treatment solution of B. subtilis, nordox, metalaxyl fungicides. The data collected in this study were percentage of germination, damping off due to pathogen R. solani, plant height, plant fresh weight, and percentages of R. solani incidence on 14 DAP. The results showed that talc powder and corn flour were the best inner carrier to be used in sorage formulation of antagonistic Bacillus. Formulated Bacillus subtilis TM4 showed no negative affect on seed germination and able to suppress the development of R. solani in greenhouse.

The paper deals with the verification of several etymological versions, suggested for interpretation of hydronyms (i.e. names of water geographical objects) of ancient Slovakia. Earlier these lexical units were classified as elements of Iranian (Sarmatian and Alanian) substratum in local Slavic historical toponymy. The author compares etymological versions, existing in scientific circulation, and finds out the soft spots in their argumentation and also notes the lack of proof for different contentions. The special attention is given to problematic question of ambiguity of orthography of documented forms hydronyms, because ambiguity all too often gives grounds for several (absolutely different) interpretations of one word. Consequently, here is focused on the problem of choice of a certain variant as more «authoritative» (i. e. maximally closed to primordial, etymological form) for research. Critical assessment of proposed above etymological versions uncovers new resources for genetic interpretation of five viewed hydronyms, which can be surely defined as Celt and Germanic lexical heritage in Slovak hydronymy. Among river names the primordial Germanic hydronym is pointed out; one is extended with Middle Iranian term of geographical nomenclature, which evidences about lexical reception of Germanic toponymy stratum traces in the speech practice of Sarmatian and Alanian population and consequently about both ethnoses lingual interaction. In particular Celtic and Germanic etymologies are suggested for such Slovakian hydronyms: Hasztergan, Hor. Hastrgan, Hor. Hastrgan = *Gaster-gan < Germ. *Gaster ‘stream in ravine’, extended with Iran. *kan ‘sorce, well, spring’; Kubra, Cubra = Celt. *kubr (< adj. *kumb-ro-) ‘stream, current on valley’; Metrbos = Germ. *Mittel-bach, *Mittel Bach or *Mitlpos(sky) ‘between creeks’; Nuduna = Celt. *nau-dun ‘port for boats’, ‘fortification with marina for boats’; Gardubarto, Gardubartu, Karduberka, Chaduwocha = Celt. *kar[r]-dubur = «stone water», «stone stream» + Hung. to [tava, tavat] ‘lake’, ‘pond’.

BACKGROUND: Increased frequencies of physiological episodes have been a significant concern for Naval Aviation for the last several years. These include several aircraft platforms, but no previously documented E-2D Hawkeye events. This report documents an episode in an E-2D, with multiple aircrew affected at the same time.CASE REPORT: While deployed aboard a U.S. aircraft carrier, five E-2D Hawkeyes aircrew were simultaneously exposed to the same over-pressurization during a routine sortie. Out of the five aircrew, four immediately reported hypoxic-like neurocognitive symptoms of mental slowing, difficulty concentrating, and headache. They were evaluated and treated using standard protocol according to the Physiologic Event Clinical Practice Guidelines set by the Naval Safety Center. All aircrew were treated with 100% ground level oxygen with resolution of symptoms.DISCUSSION: Although rare, physiological events may occur in multipassenger platforms such as the E-2D Hawkeye. Utilizing and strictly adhering to standard clinical practice guidelines provided an efficient process of evaluation by different flight surgeons concurrently that avoided a possible delay in treatment. After, eliminating other potential etiology for the crews symptoms, a pressure-related mechanism of injury appears to be the most probable cause.Ko SY, Rice GM. Multiple E-2D Hawkeye aircrew with neurocognitive symptoms during a single over-pressurization episode. Aerosp Med Hum Perform. 2020; 91(12):970974.

A study of variations of solar spectral irradiance (SSI) in the wave-length ranges 121.5 nm-300.5 nm for the period 1981-2009 is presented. We used various data for ultraviolet (UV) spectral lines and international sunspot number (ISSN) from interactive data centers such as SME (NSSDC), UARS (GDAAC), SORCE (LISIRD) and SIDC, respectively. We reduced these data by using the MATLsoftware package. In this respect, we revealed negative correlations of intensities of UV (289.5 nm-300.5 nm) spectral lines originating in the solar chromosphere with the ISSN index during the unusually prolonged minimum between the solar activity cycles (SACs) 23 and 24. We also compared our results with the variations of solar activity indices obtained by the ground-based telescopes. Therefore, we found that plage regions decrease while facular areas are increasing in SAC 23. However, the decrease in plage regions is seen in small sunspot groups (SGs), contrary to this, these regions in large SGs are comparable to previous SACs or even larger as is also seen in facular areas. Nevertheless, negative correlations between ISSN and SSI data indicate that these variations are in close connection with the classes of sunspots/SGs, faculae and plage regions. Finally, we applied the time series analysis of spectral lines corresponding to the wavelengths 121.5 nm-300.5 nm and made comparisons with the ISSN data. We found an unexpected increase in the 298.5 nm line for the Fe II ion. The variability of Fe II ion 298.5 nm line is in close connection with the facular areas and plage regions, and the sizes of these solar surface indices play an important role for the SSI variability, as well. So, we compared the connection between the sizes of faculae and plage regions, sunspots/SGs, chemical elements and SSI variability. Our future work will be the theoretical study of this connection and developing of a corresponding model.

Potential Biosorben of Oil Palm of Empty Bunch (TKKS) for Recovery of Phenol Waste The palm oil industry is one of the strategic industries engaged in agro – based industry are widely grown in tropical countries such as Indonesia, Malaysia and Thailand. Oil palm plantations produce solid waste, one of them in the form of empty fruit Bunche (TKKS). Utilization of the TKKS is still not optimal. Oil TKKS contains chemical compounds in the form of cellulose that can be used as a biosorben. TKKS Biosorben can be used for recovery phenolic compounds waste. Phenol is one of the components in the waste water that is very dangerous, because the toxic and corrosive to the skin as well as carcinogenic, therefore phenol classified as hazardous material (B3). The research aimed to determine the optimum absorption of phenolle waste by TKKS biosorben, determination of adsorption isotherm equation and comparing the effectiveness of the modified TKKS (BTB) biosorben and without modification (BTM). The optimum conditions of sorption included contact time, biosorben weight, the effect of pH and concentration of phenol. The results showed that the optimum conditions BTM adsorption at 120 minutes, biosorben weighs 1 gram and pH 7. BTB optimum conditions was 10 min adsorption time, biosorben weights 0.5 grams and pH 5. Adsorption capacity (Q) at the optimum conditions BTM and BTB, respectively, 84.4081 and 502.724 mg/g biosorben, this showed that the adsorption capacity of phenol by modified TKKS biosorben provided greater results. Adsorption of phenol solution by BTM and BTB follow Langmuir isotherm equation.Key word : biosorben, TKKS, phenol, adsorption, Langmuir isotherm ABSTRAK Industri kelapa sawit merupakan salah satu industri strategis yang bergerak pada sektor pertanian (agro-based industry) yang banyak berkembang di negara-negara tropis seperti Indonesia, Malaysia dan Thailand. Perkebunan kelapa sawit menghasilkan limbah padat, salah satunya berupa tandan kosong. Pemanfaatan limbah tandan kosong saat ini masih belum maksimal. Tandan Kosong Kelapa Sawit (TKKS) mengandung senyawa kimia berupa selulosa sehingga limbah TKKS dapat dimanfaatkan sebagai biosorben. Biosorben TKKS dapat digunakan untuk pengelolaan limbah senyawa fenol. Fenol merupakan salah satu komponen dalam air limbah yang sangat berbahaya, karena beracun dan bersifat korosif terhadap kulit serta karsinogenik, oleh karena itu fenol digolongkan sebagai bahan beracun dan berbahaya (B3). Tujuan penelitian adalah untuk mengetahui kondisi optimum proses sorpsi limbah fenol oleh biosorben asal TKKS, penentuan persamaan isotherm adsorpsi, serta membandingkan efektifitas biosorben TKKS yang dimodifikasi (BTB) dengan biosorben TKKS tanpa modifikasi (BTM). Kondisi optimum sorpsi meliputi waktu kontak, bobot biosorben, pengaruh pH dan konsentrasi fenol. Hasil penelitian menunjukan bahwa kondisi optimum BTM pada waktu adsorpsi 120 menit, bobot biosorben 1 gram, dan pH 7. Kondisi optimum BTB adalah waktu adsorpsi 10 menit, bobot biosorben 0,5 gram, dan pH 5. Kapasitas adsorpsi (Q) pada kondisi optimum BTM dan BTB berturut-turut adalah 84,4081 dan 502,724 μg/g biosorben, hal ini menunjukan bahwa kapasitas adsorpsi fenol oleh biosorben TKKS yang dimodifikasi memberikan hasil yang lebih besar. Adsorpsi larutan fenol oleh BTM dan BTB mengikuti persamaan isoterm Langmuir.Kata Kunci : Biosorben, TKKS, Fenol, Adsorpsi, isotherm Langmuir

Context.—The pioneering works on molecular classification (MC) by Perou and Sorlie et al in the early 2000s using global gene expression profiling identified 5 intrinsic subtypes of invasive breast cancers (IBCs): luminal A, luminal B, normal breast-like, HER2-enriched, and basal-like subtypes, each unique in incidence, survival, and response to therapy. Because the application of gene expression profiling in daily practice is not economical or practical at the present time, many investigators have studied the use of immunohistochemical (IHC) surrogates as a substitute for determining the MC of IBC. Objective.—To discuss the continuing efforts that have been made to develop clinically significant and readily available IHC surrogates for the MC of IBC. Data Sources.—Data were obtained from pertinent peer-reviewed English-language literature. Conclusions.—The most commonly used IHC surrogates are estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2), dividing IBC into luminal, HER2, and triple-negative subtypes. The addition of Ki-67, cytokeratin 5, and epidermal growth factor receptor (EGFR) separates luminal B from luminal A subtypes, and basal-like subtype from triple-negative breast cancer. More recently, biomarkers such as androgen receptor and p53 have been shown to further stratify these molecular subtypes. Although many studies of IHC-based MC have shown clinical significance similar to gene expression profiling–defined MC, its critical limitations are: (1) a lack of standardization in terminology, (2) a lack of standardization in biomarkers used for each subtype, and (3) the lack of a uniform cutoff for each biomarker. A panel of IHC surrogates for each subtype of IBC is proposed.

Purpose The purpose of this paper is to propose a model for a two-agent multi-target-searching scenario in a two-dimensional region, where some places of the region have limited resource capacity in terms of the number of agents that can simultaneously pass through those places and few places of the region are unreachable that expand with time. The proposed cooperative search model and Petri net model facilitate the search operation considering the constraints mentioned in the paper. The Petri net model graphically illustrates different scenarios and helps the agents to validate the strategies. Design/methodology/approach In this paper, the authors have applied an optimization approach to determine the optimal locations of base stations, a cooperative search model, inclusion–exclusion principle, Cartesian product to optimize the search operation and a Petri net model to validate the search technique. Findings The proposed approach finds the optimal locations of the base stations in the region. The proposed cooperative search model allows various constraints such as resource capacity, time-dependent unreachable places/obstacles, fuel capacities of the agents, two types of targets assigned to two agents and limited sortie lengths. On the other hand, a Petri net model graphically represents whether collisions/deadlocks between the two agents are possible or not for a particular combination of paths as well as effect of time-dependent unreachable places for different combination of paths are also illustrated. Practical implications The problem addressed in this paper is similar to various real-time problems such as rescue operations during/after flood, landslide, earthquake, accident, patrolling in urban areas, international borders, forests, etc. Thus, the proposed model can benefit various organizations and departments such as rescue operation authorities, defense organizations, police departments, etc. Originality/value To the best of the authors’ knowledge, the problem addressed in this paper has not been completely explored, and the proposed cooperative search model to conduct the search operation considering the above-mentioned constraints is new. To the best of the authors’ knowledge, no paper has modeled time-dependent unreachable places with the help of Petri net.

Natural disturbances, such as fire and insect outbreaks, play important roles in natural forest dynamics, which are characterized over long time scales by changes in stand composition and structure. Individual-based forest simulators could help explain and predict the response of forest ecosystems to different disturbances, silvicultural treatments, or environmental stressors. This study evaluated the ability of the SORTIE-ND simulator to reproduce post-disturbance dynamics of the boreal mixedwoods of eastern Canada. In 1991 and 2009, we sampled all trees (including seedlings and saplings) in 431 (256 m2) plots located in the Lake Duparquet Research and Teaching Forest (western Quebec). These plots were distributed in stands originating from seven wildfires that occurred between 1760 and 1944, and which represented a chronosequence of post-disturbance stand development. We used the 1991 inventory data to parameterize the model, and simulated short- to long-term natural dynamics of post-fire stands in both the absence and presence of a spruce budworm outbreak. We compared short-term simulated stand composition and structure with those observed in 2009 using a chronosequence approach. The model successfully generated the composition and structure of empirical observations. In long-term simulations, species dominance of old-growth forests was not accurately estimated, due to possible differences in stand compositions following wildfires and to differences in stand disturbance histories. Mid- to long-term simulations showed that the secondary disturbance incurred by spruce budworm did not cause substantial changes in early successional stages while setting back the successional dynamics of middle-aged stands and accelerating the dominance of white cedar in late-successional post-fire stands. We conclude that constructing a model with appropriate information regarding stand composition and disturbance history considerably increases the strength and accuracy of the model to reproduce the natural dynamics of post-disturbance boreal mixedwoods.

Purpose The purpose of this paper is to propose a model for a target searching problem in a two-dimensional region with time constraints. The proposed model facilitates the search operation by minimizing the mission time and fuel usage, and the search operation is performed by a set of agents divided into a number of groups. Design/methodology/approach The authors have applied optimization techniques, Cartesian product, inclusion–exclusion principle, cooperative strategy, Shapley value, fuzzy Shapley function and Choquet integral to model the problem. Findings The proposed technique optimizes the placement of base stations that minimizes the sortie length of the agents. The results show that the cooperative strategy outperforms the non-cooperative strategy. The Shapley values quantify the rewards of each group based on their contributions to the search operation, whereas the fuzzy Shapley values determine the rewards of each group based on their contributions and level of cooperation in the search operation. Practical implications The proposed model can be applied to model many real-time problems such as patrolling in international borders, urban areas, forests and managing rescue operations after natural calamities, etc. Therefore, defence organizations, police departments and other operation management sectors will be benefitted by applying the proposed approach. Originality/value To the best of the authors’ knowledge, determining the optimal locations of base stations in a region is not explored in the existing works on target searching problems with fuel constraints. The proposed approach to cooperatively search the targets in a region is new. Introducing the Shapley function and fuzzy Shapley function is a novel idea to quantify the rewards of each group based on their contributions and level of cooperation in the search operation. This paper addresses these unexplored areas.

Abstract. Due to the important contribution of nitrous acid (HONO) to OH radicals in the atmosphere, various technologies have been developed to measure HONO. Among them, wet-denuder–ion-chromatography (WD/IC) is a widely used measurement method. Here, we found interferences with HONO measurements by WD/IC based on a comparison study of concurrent observations of HONO concentrations using a WD/IC instrument (Monitor for AeRosols and Gases in ambient Air, MARGA) and long-path absorption photometer (LOPAP) at the Station for Observing Regional Processes of the Earth System (SORPES) in eastern China. The measurement deviation of the HONO concentration with the MARGA instrument, as a typical instrument for WD/IC, is affected by two factors. One is the change in denuder pH influenced by acidic and alkaline gases in the ambient atmosphere, which can affect the absorption efficiency of HONO by the wet denuder to underestimate the HONO concentration by up to 200 % at the lowest pH. The other is the reaction of NO2 oxidizing SO2 to form HONO in the denuder solution to overestimate the HONO concentration, which can be increased by to 400 % in denuder solutions with the highest pH values due to ambient NH3. These processes are in particularly important in polluted east China, which suffers from high concentrations of SO2, NH3, and NO2. The overestimation induced by the reaction of NO2 and SO2 is expected to be of growing importance with the potentially increased denuder pH due to the decrease in SO2. We further established a method to correct the HONO data measured by a WD/IC instrument such as the MARGA. In case a large amount WD/IC-technique-based instruments are deployed with the main target of monitoring the water-soluble composition of PM2.5, our study can help to obtain a long-term multi-sites database of HONO to assess the role of HONO in atmospheric chemistry and air pollution in east China.

Written sources for the history of sub-Saharan Africa (with the exception of East Africa) only begin to appear with the inception of Arabic records from the ninth century onwards, and these are restricted to the Sahel and the northern part of the savanna belt. European sources begin in the mid-fifteenth century, first for Senegambia. They, in turn, confine themselves to the coast and its immediate hinterland, as well as the navigable courses of rivers, with few, and often vague, references to the interior. For the time before the early written sources and for those extensive areas which only much later entered the horizon of writing witnesses, other sources illuminating the past have to be traced and tapped. Among such non-written sources are the findings of anthropology and archeology, of research in oral tradition and place names. Because of their interdependence, working with different source types contributes to the reliability of results.So far little systematic use has been made of place names as a source for African history. Houis' 1958 dictum, “la toponymie ouest-africaine n'est pas encore sortie de l'oeuf,” has not yet been proven obsolete. In this paper I hope to stimulate the process of shedding the egg shells. It is intended as a short introduction to the potential historical treasures place names may yield, into their characteristics, and into some principles guiding their interpretation. With the aim at illustrating my arguments, I add examples of place names. These I have chosen from two areas which, at first sight, seem to have been selected rather randomly; southern Senegambia and Germany. In fact both areas share few features, both geographically and historically. Two reasons have led me to select them. First, they simply are the regions I know best. Secondly, the recourse to German place names is instructive, as research on place names has been undertaken there for more than a century, leading to a wide range of data and to the accumulation of rich research experience.

The audirory-evoked neuromagnetic field elicited by single vowel formants and two-formant vowels was recorded under active listening conditions using a 37-channel magnetometer. There were three single formants with formant with a formant frequency of 200, 400, and 800 Hz, another single fromant with a fromant frequency of 2600 Hz, and three vowels that were constructed by linear superimposition of the high-onto one of the low-frequency formants. P50m and N100m latency values were inversely correlated with the formant frequency of single location was obtained along the postero-anterior axiz, which is orthogonal to the well-established latero-medial tonotopic gradient. Regardless of whether single formants or first formants of vowels were considered N100m sources were more anterior and sustained field sources wre more posterior for higher-frequency than for lower-frequency formants. The velocity of the apparent posterior-to-anterior movement across cortical sorface of N100m sources first reported by Rogers et al. [Rogers, R.L., Papanicolaou, A.C., Baumann, S.B., Saydjari,C., & Eisenberg, H.M. (1990). Neuromagnetic evidence of a dynamic excitation pattern generating the N100 auditory response. Electroencephalography and Clinical Neurophy-siology,77,237-240] decreased as a function of latency. The amount of deceleration was positively correlated with formant frequency. responses to the vowels were superadditive, indicating that the processes elicited by the constituents of composite stumuli interact at one or more stages of the afferent auditory pathway. Such interaction may account for the absence of a lateral-to-medial tonotopic mapping of first formant frequency. The source topography found may reflect activity in auditory fields adjacent to AI with the strenght of the contribution varying with formant frequency. Altematively, it may reflect sharpness-of-tuning and inhbitory response-area asymmetry gradients along isofrequency stripes within AI. Either alternative may be interpreted in terms of a sprctral blurring mechanism that abstracts spectral envelope information form the details of spectral composition, an important step towards the formation of invariant phonetic percepts.

In this paper, the formation of the Caliphate, which emerged as a scientific discipline by Mu‘tazila in Hijri 2nd Century, the general situation and basic features of the Ottoman education system up to the 16th century and the works of Kalām taught in madrasas are examined. This study is a descriptive and comparative study. This research will use the classical soruces of the history of Islam, the history of sects in islams and kalam. In spite of some unfavorable reactions which have been exhibited against Ilm al-Kalām since the earliest period of the Ottoman period, Ilm al-Kalām has been able to enter the curriculum of the Ottoman madrasas and become a knowledge discipline favored by the Ottoman sultans and their ʿulamās. The most important contributor to this was the Ottoman sultans, who showed great interest in science, valued the freedom of thought and belief, and provided free thinking and working environment in the Kalām and philosophical areas. In this respect, the Ottoman lands became a science and culture center and a great deal of scholars have been trained in scientific and religious areas up to the 16th century, and in these areas, they produced lots of precious works. Among these works, there are not only independent studies on akaid and Kalām but also works belonging to other disciplines which study the fields of faith, worship and morality together. Ilm al-Kalām came to the fore in the Ottoman education system with the help of these scholars who interested in Ilm al-Kalām. Through the middle of the 16th century, the importance given to the education of Kalām was decreased due to a number of reasons and Kalām was replaced by fiqh. The Anti-Kalām thought reached such a point that many books on Kalām theology had been removed from the madrasah course curriculum and some scholars gave fatwas that say that learning Kalām was forbidden. The findings state that the science of Kalam was considered important until 16th century after which it has lost its importance in the educational system. This caused the loss the culture of criticism and the philosophical though has been ignored. Key Words: Ottoman, Kalām, Philosophy, Ahl al-Sunna, Madrasah

Sistem keamanan rumah merupakan implementasi yang harus dilakukan untuk meningkatkan keamanan dari kejadian yang tidak diinginkan. Beberapa implementasi hanya memberikan notifikasi sederhana berupa alarm dan tidak menjadi bukti yang kuat apabila terjadi pencurian. Salah satu solusi yang dilakukan adalah penempatan kamera untuk memantau keamanan rumah secara real time diintegrasikan dengan penyimpanan cloud. Bluemix merupakan salah satu provider untuk aplikasi cloud yang memiliki layanan pengolahan dan penyimpanan data, akses aplikasi mobile, pengawasan serta Internet of Things (IoT). Sistem yang diimplementasikan adalah integrasi Raspberry Pi dengan layanan Bluemix untuk melakukan pengawasan keamanan rumah dan memberikan notifikasi kepada pengguna. Sistem mendeteksi jarak menggunakan sensor HC-SR04 terhadap objek dan apabila jarak melewati acuan, hal tersebut adalah indikasi terjadinya pencurian. Berikutnya sistem akan menyalakan buzzer sebagai keluaran suara dan mengaktifkan kamera untuk mengambil gambar lalu diunggah ke object storage Bluemix. Langkah berikutnya yaitu layanan IBM push notification memberikan notifikasi ke perangkat Android pengguna. Pengujian dilakukan dengan menghalangi pembacaan sensor sehingga terjadi indikasi pencurian. Hasilnya adalah sistem berhasil menyalakan buzzer, mengambil gambar lalu diunggah ke Bluemix, dan notifikasi berhasil masuk pada Android. Notifikasi diterima oleh file browser pada perangkat Android dan dilakukan sinkronisasi dengan object storage untuk melakukan pengunduhan berkas gambar yang telah diunggah sebelumnya.Kata kunci: Bluemix, Raspberry Pi, object sorage, IBM push notification Home security system is an implementation that needs to be done to improve the security of unwanted events. Some implementations only provide a simple notification such as alarm and cannot become strong evidence in case of theft. One of the solutions is camera placement to monitor home security in real time integrated with cloud storage. Bluemix is a provider for cloud applications that have data processing and storage services, mobile application access, monitoring and Internet of Things (IoT). System implemented was integration of Raspberry Pi with Bluemix services to conduct home security surveillance and provide notification to user. System detected distance using HC-SR04 sensor to object and if distance passes the reference, it was an indication of theft. Next, system will turned on buzzer as a sound output and activating the camera to take picture and uploaded to Bluemix Object Storage. Next step was IBM push notification service giving notification to user's Android device. The testing was done by blocking the sensor readings so that there was an indication of theft. The result was system succeeded in turning on the buzzer, taking pictures, uploading pictures to Bluemix, and notification successfully logged on Android. Notifications are received by the file browser on Android device and synchronized with object storage to download image files that have been uploaded previously.Keywords: Bluemix, Raspberry Pi, object storage, IBM push notification

AbstractThis study seeks to improve numerical simulations of the key physics occurring in CO2 enhanced oil recovery (CO2-EOR) processes, with a particular focus on the transition from immiscible to miscible displacements. In the previous work, we have investigated interactions between compositional effects and the underlying heterogeneities of the flow field in near-miscible floods (Wang et al. in Transp Porous Media 129(3):743–759, 2019a). In this current study, we have further analysed the effects of reduction in interfacial tension (IFT) on the flow behaviour, as motivated by the study on the film-flow mechanism previously presented by Sorbie and van Dijke (SPE improved oil recovery symposium, Society of Petroleum Engineers, 2010). We identify two clear mechanisms of oil recovery that may occur in near-miscible CO2 (or other gas) injection processes, which we denote, MCE, as oil stripping or conventional compositional effects, and MIFT as lower IFT oil film-flow effects. The latter MIFT effects are described by an enhanced hydrocarbon relative permeability in the near-miscible three-phase relative permeabilities (3PRP). Various combinations between the MCE and MIFT mechanisms were tested by numerical simulations to evaluate the impact of each mechanism on the flow behaviour, i.e. their separate and joint effects on quantities such as the local oil displacement efficiency, phase flow vectors and the ultimate oil recovery. When acting in combination, the oil stripping and IFT effects can greatly improve the local displacement performance even when viscous fingering flow occurs. Viscous fingering is well known to lead to bypassed oil in the “non-preferential” flow paths between the main fingers. We show that the remaining oil in these non-preferential flow paths (i.e. bypassed oil) can be efficiently recovered by the combined MCE and MIFT mechanisms, but only with the application of water alternating gas (WAG). In contrast to oil stripping effects, the IFT effect is not dependent on continuous contact between oil and CO2. Instead, the remaining oil is mobilized by gas as the IFT is reduced and can be efficiently produced by subsequent water injection. This MIFT mechanism has much less impact in cases with continuous CO2 injection compared to its efficiency in WAG. This is because during continuous injection, gas fingers are dominant in the preferential flow paths, and therefore the local displacement efficiency is very good, but only in these preferential routes. On the other hand, WAG is able to make full use of the IFT effects because of its relatively stable displacing front, which allows the MIFT mechanism to contribute. In this study, the effects of using different three-phase relative permeability methods were investigated and, as expected, different methods yielded different results. However, an important observation is that when IFT effects (MIFT) were included, there was much less difference in the final oil recovery using the different 3PRP models; our analysis shows why this is the case.

Summary This paper describes the design procedures that led to favorable incremental oil production and reduced water production during 12 years of successful polymer flooding in the Daqing oil field. Special emphasis is placed on some new design factors that were found to be important on the basis of extensive experience with polymer flooding. These factors include (1) recognizing when profile modification is needed before polymer injection and when zone isolation is of value during polymer injection, (2) establishing the optimum polymer formulations and injection rates, and (3) time-dependent variation of the molecular weight of the polymer used in the injected slugs. For some Daqing wells, oil recovery can be enhanced by 2 to 4% of original oil in place (OOIP) with profile modification before polymer injection. For some Daqing wells with significant permeability differential between layers and no crossflow, injecting polymer solutions separately into different layers improved flow profiles, reservoir sweep efficiency, and injection rates, and it reduced the water cut in production wells. Experience over time revealed that larger polymer-bank sizes are preferred. Bank sizes grew from 240-380 mg/L·PV during the initial pilots to 640 to 700 mg/L·PV in the most recent large-scale industrial sites [pore volume (PV)]. Economics and injectivity behavior can favor changing the polymer molecular weight and polymer concentration during the course of injecting the polymer slug. Polymers with molecular weights from 12 to 35 million Daltons were designed and supplied to meet the requirements for different reservoir geological conditions. The optimum polymer-injection volume varied around 0.7 PV, depending on the water cut in the different flooding units. The average polymer concentration was designed approximately 1000 mg/L, but for an individual injection station, it could be 2000 mg/L or more. At Daqing, the injection rates should be less than 0.14-0.20 PV/year, depending on well spacing. Introduction Many elements have long been recognized as important during the design of a polymer flood (Li and Niu 2002; Jewett and Schurz 1970; Sorbie 1991; Vela et al. 1976; Taber et al. 1997; Maitin 1992; Koning et al. 1988; Wang et al. 1995; Wang and Qian 2002; Wang et al. 2008). This paper spells out some of those elements, using examples from the Daqing oil field. The Daqing oil field is located in northeast China and is a large river-delta/lacustrine-facies, multilayer, heterogeneous sandstone in an inland basin. The reservoir is buried at a depth of approximately 1000 m, with a temperature of 45°C. The main formation under polymer flood (i.e., the Saertu formation) has a net thickness ranging from from 2.3 to 11.6 m with an average of 6.1 m. The average air permeability is 1.1 µm2, and the Dykstra-Parsons permeability coefficient averages 0.7. Oil viscosity at reservoir temperature averages approximately 9 mPa·s, and the total salinity of the formation water varies from 3000 to 7000 mg/L. The field was discovered in 1959, and a waterflood was initiated in 1960. The world's largest polymer flood was implemented at Daqing, beginning in December 1995. By 2007, 22.3% of total production from the Daqing oil field was attributed to polymer flooding. Polymer flooding should boost the ultimate recovery for the field to more than 50% OOIP--10 to 12% OOIP more than from waterflooding. At the end of 2007, oil production from polymer flooding at the Daqing oil field was more than 11.6 million m3 (73 million bbl) per year (sustained for 6 years). The polymers used at Daqing are high-molecular-weight partially hydrolyzed polyacrylamides (HPAMs). During design of a polymer flood, critical reservoir factors that traditionally receive consideration are the reservoir lithology, stratigraphy, important heterogeneities (such as fractures), distribution of remaining oil, well pattern, and well distance. Critical polymer properties include cost-effectiveness (e.g., cost per unit of viscosity), resistance to degradation (mechanical or shear, oxidative, thermal, microbial), tolerance of reservoir salinity and hardness, retention by rock, inaccessible pore volume, permeability dependence of performance, rheology, and compatibility with other chemicals that might be used. Issues long recognized as important for polymer-bank design include bank size (volume), polymer concentration and salinity (affecting bank viscosity and mobility), and whether (and how) to grade polymer concentrations in the chase water. This paper describes the design procedures that led to favorable incremental oil production and reduced water production during 12 years of successful polymer flooding in the Daqing oil field.

Abstract Introduction: Climate change affects people, not only through environmental exposures and health outcomes, but how they live their lives. Consequences will affect various sectors, ranging from tourism to water to energy development—areas where people live, work, and enjoy. Because of these forced changes, people must adapt. Methods: A scoping review was created to understand climate change vulnerability alongside adaption and resiliency measures that are being implemented in each continent of the world; this review is a subset of information from Zolnikov, T. R. (2019). Global Adaptation and Resilience to Climate Change. In: T. R. Zolnikov (Ed.). Cham, Switzerland; Springer International Publishing. Results: It was determined that adaptive capacity differs worldwide. This is likely because the capacity to adapt and change is linked to both social and economic development; some regions in the world may not be sufficiently equipped and thus, may not be able to mitigate or adapt to changes. Such was the case in Australia, Europe, and North and South America, where economic resources were more available, and the general culture of climate change appeared to be more developed through various policies. Whereas, for example, Asia and Africa were less economically developed and focused less on individual changes, but joined larger climate change agreements, such as the Kyoto Protocol. Conclusions: The objective of this review was to understand the differences that may help or hinder progress under the new world set forth by climate change. The information provided evidence that a “one size fits all” approach does not work to promote climate change resiliency. In fact, each continent in the world suffers from some barriers to change, while also offering elements of success that can be shared. It is these types of lessons learned that can help pull the world together to learn from each other and promote the effectiveness of measures as well as the capacity for populations to adapt. Keywords: Climate Change, Environmental Health, Global Health

Abstract Sorce and Wald proposed a new version of gedanken experiments to examine the weak cosmic censorship conjecture (WCCC) in Kerr-Newmann black holes. However, their discussion only includes the second-order approximation of perturbation and there exists an optimal condition such that the validity of the WCCC is determined by the higher-order approximations. Therefore, in this paper, we extended their discussions into the high-order approximations to study the WCCC in a nearly extremal Kerr black hole. After assuming that the spacetime satisfies the stability condition and the perturbation matter fields satisfy the null energy condition, based on the Noether charge method by Iyer and Wald, we completely calculate the first four order perturbation inequalities and discuss the corresponding gedanken experiment to overspin the Kerr black hole. As a result, we find that the nearly extremal Kerr black holes cannot be destroyed under the fourth-order approximation of perturbation. Then, by using the mathematical induction, we strictly prove the nth order perturbation inequality when the first (n − 1) order perturbation inequalities are saturated. Using these results, we discuss the first 100 order approximation of the gedanken experiments and find that the WCCC in Kerr black hole is valid under the higher-order approximation of perturbation. Our investigation implies that the WCCC might be strictly satisfied in Kerr black holes under the perturbation level.

International audience We introduce an algorithm to determine when a sorting operation, such as stack-sort or bubble-sort, outputs a given pattern. The algorithm provides a new proof of the description of West-2-stack-sortable permutations, that is permutations that are completely sorted when passed twice through a stack, in terms of patterns. We also solve the long-standing problem of describing West-3-stack-sortable permutations. This requires a new type of generalized permutation pattern we call a decorated pattern. On introduit un algorithme qui détermine quand un opérateur de tri (tels que le tri par une pile, ou le tri-bulle) produit un motif donnè en sortie. Cet algorithme fournit une nouvelle preuve de la caractérisation des permutations 2-triables au sens de West (c'est-à-dire des permutations qui sont triées complètement par deux passages dans une pile) par des motifs interdits. On résout aussi le problème longtemps ouvert de la caractérisation des permutations 3-triables au sens de West. Ceci demande de définir un nouveau type de motifs généralisés, appelè motif décoré.

Abstract Key message Model simulation results suggest that forests in the Sierra Nevada mountains of California will tend to increase in density and basal area in the absence of fire over the next century, and that climate change will favor increases in drought-tolerant species. Context Climate change is projected to intensify the natural summer drought period for Mediterranean-climate forests. Such changes may increase tree mortality, change species interactions and composition, and impact ecosystem services. Aims To parameterize SORTIE-ND, an individual-based, spatially explicit forest model, for forests in the Sierra Nevada, and to model forest responses to climate change. Methods We use 3 downscaled GCM projections (RCP 8.5) to project forest dynamics for 7 sites at different elevations. Results Basal area and stem density tended to increase in the absence of fire. Climate change effects differed by species, with more drought-tolerant species such as Jeffrey pine (Pinus jeffreyi A.Murray bis) and black oak (Quercus kelloggii Newb.) exhibiting increases in basal area and/or density. Conclusion Increasing forest density may favor carbon sequestration but could increase the risk of high-severity fires. Future analyses should include improved parameterization of reproduction and interactions of disturbance with climate effects.

International audience Multi-user multimodal interactive systems involve multiple users who can use multiple interaction modalities. Multi-user multimodal systems are becoming more prevalent, especially systems based on large shared multi-touch surfaces or video game centers such as Wii or Xbox. In this article we address the description of the tasks with such interactive systems. We review existing notations for the description of tasks with a multi-user multimodal interactive system and focus particularly on tree-based notations. For elementary tasks (e.g. actions), we also consider the notations that describe multimodal interaction. The contribution is then a comparison of existing notations based on a set of organized concepts. While some concepts are general to any notation, other concepts are specific to human-computer interaction, or to multi-user interaction and finally to multimodal interaction. De nombreux systèmes interactifs, professionnels ou grand public, permettent conjointement l’interaction multiutilisateur et multimodale. Un système interactif est multimodal lorsqu’un utilisateur peut interagir avec le système par l’usage de plusieurs modalités d’interaction (en entrée ou en sortie) de façon parallèle ou non. Nous constatons que de plus en plus de systèmes multiutilisateurs ou collecticiels sont multimodaux, comme ceux construits autour d’une surface interactive et les consoles de jeu de type Wii ou Xbox. Nous traitons dans cet article de la description des tâches-utilisateur avec de tels systèmes interactifs multiutilisateurs et multimodaux. Précisément, nous dressons un panorama des notations existantes permettant la description des tâches mono ou multi-utilisateur avec une attention particulière pour les notations à base d’arbre de tâches. Nous focalisons aussi sur les tâches élémentaires ou actions mono/multi-modales de l’utilisateur en considérant les notations de description de l’interaction multimodale. Pour cela, nous proposons une étude comparative d'un ensemble de notations de description selon une grille d’analyse regroupant des concepts généraux à l’interaction et des concepts propres à l’interaction multiutilisateur et multimodale.

Abstract Disobedience among military personnel is common and can be highly consequential, given the military's centrality to the conduct of foreign policy and war. Despite this, scholars of international affairs typically assume that subordinates in the military obey their orders. While scholarship on military politics acknowledges the prevalence of disobedience, it focuses on group-level forms of resistance and characterizes all such behavior as undesirable. Both of these analytical choices obscure the fact that individuals in the military can respond to orders they do not like in any number of ways. Building on existing work on civil–military relations and military decision-making, this article develops a novel conceptual typology of individual-level disobedience in military organizations. Drawing on dozens of diverse examples, it shows how such resistance is best categorized into four broad types: defiance, refinement, grudging obedience, and exit. Further, it demonstrates the advantages of adopting this typology. In particular, it highlights how military disobedience can be either disloyal or loyal; disobedience can be productive by fostering innovation, adaptability, or cohesion in military organizations. In addition to providing new variables for research on military politics, this typology also points to underexplored linkages between behaviors that have so far been studied separately, such as desertion, surrender, and mutiny. La désobéissance du personnel militaire est courante et peut avoir de lourdes conséquences selon la centralité de l'Armée dans la conduite de la politique étrangère et de la guerre. Malgré cela, les chercheurs en affaires internationales présupposent généralement que les subordonnés de l'Armée obéissent aux ordres qui leur sont donnés. Bien que les recherches sur la politique militaire admettent la prévalence de la désobéissance, ces dernières se concentrent sur les formes de résistance au niveau Groupes et caractérisent toutes un tel comportement comme indésirable. Ces deux choix analytiques obscurcissent le fait que les individus de l'Armée peuvent réagir aux ordres qui ne leur plaisent pas de bien des façons. Cet article s'appuie sur des travaux existants portant sur les relations entre civils et militaires et sur la prise de décisions militaires pour développer une nouvelle typologie conceptuelle de la désobéissance au niveau Individus dans les organisations militaires. Il s'inspire de dizaines d'exemples divers pour montrer à quel point il est préférable de classer une telle résistance en quatre grands types: Défiance, Peaufinement, Obéissance à contrecœur et Sortie de l'Armée. De plus, cet article montre les avantages qu'offre l'adoption de cette typologie. Il met en particulier en évidence la mesure dans laquelle la désobéissance militaire peut être soit loyale, soit déloyale; la désobéissance peut s'avérer productive lorsqu'elle encourage l'innovation, l'adaptabilité ou la cohésion dans les organisations militaires. En plus de fournir de nouvelles variables pour les recherches sur la politique militaire, cette typologie montre également des liens insuffisamment explorés entre des comportements qui ont jusqu'ici été étudiés séparément, tels que la désertion, l'abandon et la mutinerie. La desobediencia entre el personal militar es común y puede tener consecuencias de importancia debido al lugar central del ejército en la conducción de la política exterior y la guerra. A pesar de esto, los estudiosos de los asuntos internacionales suelen dar por sentado que los subordinados en el ejército obedecen las órdenes. Si bien los estudiosos de la política militar reconocen la prevalencia de la desobediencia, se centran en las formas de resistencia a nivel de grupo y caracterizan todo ese comportamiento como indeseable. Ambas opciones analíticas ocultan el hecho de que las personas en el ejército pueden responder de muchas maneras a las órdenes que no son de su agrado. A partir de trabajos existentes acerca de las relaciones cívico-militares y la toma de decisiones en el ejército, este artículo desarrolla una novedosa tipología conceptual de la desobediencia a nivel individual en las organizaciones militares. A través de numerosos ejemplos diversos, muestra cómo esa resistencia se clasifica mejor en cuatro categorías amplias: desafío, perfeccionamiento, obediencia de mala gana y retirada. Además, muestra las ventajas de adoptar esta categorización. En concreto, destaca cómo la desobediencia militar puede ser desleal o leal. Puede ser productiva al fomentar la innovación, la adaptabilidad o la cohesión en las organizaciones militares. Además de proporcionar nuevas variables para la investigación en materia de política militar, esta categorización también señala vínculos poco explorados entre comportamientos que hasta el momento se han estudiado por separado, como la deserción, la rendición y el motín.

Abstract The growing literature on desertion from insurgent groups focuses almost exclusively on male deserters, with few comparisons to combatants who choose to stay and little consideration of women combatants or the gendered norms and narratives that restrict combatants’ options. As governments increasingly emphasize “counter-narratives” to prevent radicalization and encourage disengagement from non-state armed groups, there is insufficient empirical evidence on how such framing contests between governments and insurgents might affect how recruits calculate their options. With “deradicalization” programs proliferating globally, and disarmament, disengagement, and reintegration (DDR) programs continuing to perpetuate gender stereotypes, it is critical to examine why some men and women disengage from violence while others stay, how they evaluate these decisions, and how gendered norms affect these decisions. Based on over 100 interviews with men and women ex-combatants across seven departments of Colombia, this article examines the effects of framing contests between the FARC guerrillas and the Colombian government, in which gender norms and gendered power dynamics play key roles. This paper argues that these gendered framing contests are critical to individual combatants’ disengagement decisions and, in particular, influence how women combatants perceive their alternatives and manage their exit pathways out of non-state armed groups. Las crecientes publicaciones sobre la deserción de combatientes de los grupos rebeldes se centran casi exclusivamente en los desertores hombres, con pocas comparaciones con los combatientes que deciden quedarse y poca consideración de las combatientes mujeres o la influencia del género en las normas y la narrativa que restringen las opciones de los combatientes. A medida que los gobiernos hacen cada vez más hincapié en las “contranarrativas” para evitar la radicalización y fomentar la desmovilización de los grupos armados no estatales, no hay pruebas empíricas suficientes sobre cómo dichas disputas de estructuración entre los gobiernos y los rebeldes podrían afectar la manera en que los reclutas determinan sus opciones. Con la proliferación de programas de “desradicalización” en todo el mundo, y dado que las iniciativas de desarme, desmovilización y reintegración (Disarmament, Disengagement, and Reintegration, DDR) siguen perpetuando los estereotipos de género, es fundamental analizar por qué algunos hombres y mujeres se desvinculan de la violencia mientras que otros no, cómo evalúan estas decisiones y de qué manera las normas en función del género influyen en estas determinaciones. A partir de más de 100 entrevistas a hombres y mujeres excombatientes en siete departamentos de Colombia, este artículo analiza los efectos de las disputas de estructuración entre la guerrilla de las FARC y el gobierno colombiano, donde las normas y las dinámicas del poder en función del género juegan un papel clave. En este documento, se sostiene que dichas disputas de estructuración influenciadas por el género son fundamentales para las decisiones de desmovilización de los combatientes y, en especial, influyen en la manera en que las combatientes mujeres perciben sus alternativas y gestionan sus vías de escape de los grupos armados no estatales. La littérature croissante portant sur la désertion des groupes d'insurgés se concentre presque exclusivement sur les hommes déserteurs, avec peu de comparaisons avec les combattants qui choisissent de rester et peu de considération pour les femmes combattantes ou les normes et récits sexospécifiques qui limitent le panel de combattants abordés. Alors que les gouvernements mettent de plus en plus l'accent sur les « contre-récits » pour prévenir la radicalisation et encourager le désengagement des groupes armés non étatiques, les preuves empiriques de la mesure dans laquelle un tel cadrage des conflits entre gouvernements et insurgés pourrait affecter la façon dont les recrues calculent leurs options sont insuffisantes. Tandis que les programmes de « déradicalisation » prolifèrent dans le monde entier et que les programmes de désarmement, de désengagement et de réintégration continuent à perpétuer les stéréotypes de genre, il est essentiel d’étudier les raisons pour lesquelles certains hommes et certaines femmes se désengagent de la violence contrairement à d'autres, les facteurs que ces personnes prennent en compte dans leur décision, et la manière dont les normes sexospécifiques affectent ces décisions. Cet article s'appuie sur plus de 100 entretiens avec des hommes et femmes ayant précédemment combattu dans sept départements de Colombie pour analyser les effets du cadrage des conflits entre les insurgés des FARC et le gouvernement colombien, dans lesquels les normes de genre et les dynamiques de pouvoir liées au genre jouent des rôles clés. Il soutient que ce cadrage sexospécifique des conflits est essentiel aux décisions de désengagement des combattants individuels, en particulier pour influencer la manière dont les combattantes perçoivent leurs alternatives et gèrent leurs voies de sortie des groupes armés non-étatiques.

Background: The optimal antithrombotic regimen for patients with coexistent atrial fibrillation (AF) and coronary artery disease (CAD) requiring percutaneous coronary intervention (PCI) remains controversial.Methods: We performed a chart review of 2,645 consecutive patients with non-ST elevation or ST elevation myocardial infarction at a regional cardiac centre, to examine the clinical characteristics and discharge antithrombotic medications of patients with coexistent AF (known or new onset AF with CHADS2 ≥1), treated with PCI.Results: Among 2,645 patients, 94 eligible patients were analyzed and 30 (32%) were prescribed triple therapy (TT) at hospital discharge. CHADS2 score was the major predictor of the decision to prescribe TT (P =0.002).Conclusion: Approximately one-third of the patients with AF undergoing PCI were prescribed TT at hospital discharge. Clinicians are generally following national guidelines and internationally-developed consensus statements, and focus on stroke risk despite the risks of bleeding and insufficient evidence supporting the benefits of TT. RésuméContexte : Le régime optimal antithrombotique pour les patients atteints à la fois de fibrillation atriale (FA) et d’une coronaropathie nécessitant une angioplastie coronarienne percutanée (ACP) demeure controversé.Méthodologie: Dans un centre régional de cardiologie, nous avons examiné les dossiers médicaux de 2645 patients ayant subi un infarctus du myocarde avec ou sans sus‑décalage du segment ST. Le but consistait à analyser les caractéristiques cliniques des patients présentant une FA concomitante (ancienne ou nouvelle, avec un indice CHADS2 ≥ 1) traitée par ACP, et les médicaments antithrombotiques prescrits au moment de leur sortie de l’hôpital.Résultats: Parmi les 2645 dossiers, 94 patients admissibles ont été analysés. Trente (32 %) s’étaient vus prescrire une trithérapie (TT) à leur sortie de l’hôpital. L’indice CHADS2 était le principal indicateur prévisionnel pris en compte dans la décision de prescrire la TT (P = 0,002).Conclusion : Environ un tiers des patients atteints de FA et ayant subi une ACP se sont vus prescrire une TT à leur sortie de l’hôpital. En général, les cliniciens suivent les directives nationales et les protocoles consensuels élaborés à l’international et se concentrent sur le risque d’ictus, malgré les risques de saignements et le manque de données probantes soutenant les avantages d’une TT.BACKGROUNDDual antiplatelet therapy (DAPT) including Aspirin and a P2Y12 receptor antagonist is recommended for patients who undergo percutaneous coronary intervention (PCI) with stent implantation.1,2 DAPT is superior to oral anticoagulants (OAC) in preventing stent thrombosis, 3while OAC is superior to DAPT in reducing stroke in patients with atrial fibrillation (AF).4,5 It is estimated that 5–8% of patients sustaining an acute coronary syndrome (ACS) have concomitant AF.6,7 The optimal antithrombotic regimen for patients with coexistent AF and coronary artery disease (CAD) requiring PCI remains controversial. In patients with AF and CHADS2 stroke risk score ≥1, consensus statements suggest that triple therapy (TT), defined as a combination of DAPT + OAC, be utilized in patients undergoing PCI with ACS.8,9 However, there is data indicating no improved efficacy of treatment with TT compared with DAPT alone, while exposing patients to increased bleeding risk.7,10,11 Major bleeding has been proven to be independently associated with death in patients following an ACS.12 Therefore, balancing the thromboembolic and bleeding risk is critical in patients with a recent ACS.Large randomized trials have indicated that compared with warfarin, novel oral anticoagulants (NOAC’s) are at least as effective as, and are associated with reduced rates of major, fatal and intracranial bleeding in patients with non-valvular AF.13 Due to the favourable safety profile, NOACs are being evaluated against warfarin in patients with AF undergoing PCI. Three of these trials are ongoing (RE-DUAL PCI, AUGUSTUS, ENTRUST-AF-PCI),14–16 and the fourth is the recently published PIONEER AF-PCI trial, which showed that reduced-dose rivaroxaban combined with clopidogrel lowered the risk of bleeding compared with TT with warfarin.17Despite the emergence of these recent data, the highest risk patients remain excluded from large randomized trials, and thus sound clinical judgment will remain the cornerstone in caring for these patients. In the current study, we aim to describe the local practice patterns of clinicians making treatment decisions for patients with new or existing AF, who present with an ACS and undergo PCI.METHODSA retrospective and prospective chart review was performed on 2,645 consecutive patients presenting with ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial elevation (NSTEMI) to 3 academic hospitals affiliated with McMaster University and 8 community hospitals located in Local Health Integrated Network (LHIN) 4, Ontario, Canada from January to December 2014. Of those, 1,458 patients had undergone PCI with stent implantation; and, 124 patients were identified to have concomitant AF (Figure 1). Inclusion criteria for our study were: admission to hospital for either STEMI or NSTEMI, known or new onset AF with CHADS2 ≥ 1, coronary angiography demonstrating at least one epicardial coronary artery with a ≥70% stenosis, and successful PCI with stent implantation. Patients who expired before discharge were excluded from the analysis. Clinical and demographic characteristics of patients were summarized. DAPT and TT groups were identified by reviewing medication records from discharge summaries or copies of discharge prescriptions. DAPT was defined as Aspirin plus clopidogrel (75 mg once daily) or ticagrelor (90 mg twice daily), while TT was defined as DAPT plus an OAC; including either warfarin or novel oral anticoagulants (NOAC). We analyzed the CHADS2 and ATRIA (Anticoagulation and Risk factors in Atrial fibrillation) scores according to treatment groups.18,19 Statistical analysis was performed using SAS/STAT version 9.3 (SAS Institute Inc., Cary, NC). Categorical data was compared using Chi-square testing. Continuous data comparison was performed applying the Wilcoxon test and Cochran-Armitage test for trends. A binary logistic regression model was developed to identify the clinical predictors of discharge groups based on their CHADS 2 and ATRIA scores (Figure 2 and Figure 3). The cut-off for statistical significance was a P-value of <0.05.Figure 1. Flow chart of study cohort. Figure 2. Use of triple therapy versus dual antiplatelet therapy at the time of discharge in different stroke risk groups predicted by their CHADS2 score. Figure 3. Use of triple therapy versus dual antiplatelet therapy at the time of discharge in different bleeding risk groups predicted by their ATRIA score. RESULTSDemographic and clinical characteristics of patients are described in Table 1. Ninety four out of 124 patients with ACS and a prior or new diagnosis of AF were included in the final analysis. The mean (s.d.) age was 74 years (10 years) and 55.3% were male. In our cohort, 59.6% of patients sustained a STEMI and 54.3% had single vessel CAD. Overall, 32% (n = 30) of patients were discharged on TT of whom 55.6% were prescribed a combination of DAPT and a NOAC while the remaining patients were prescribed conventional TT (DAPT+warfarin) (Table 2). The median CHADS2 score in the DAPT and TT groups were 2 and 3, respectively (P = 0.001). The median ATRIA bleeding risk in DAPT and TT groups were 3 and 4, respectively (P = 0.008). The P-value for trend of CHADS 2 and ATRIA scores were <0.0001 and 0.001, respectively. However, these 2 trends were not significantly different from one another (P = 0.26). In a logistic regression analysis with both CHADS 2 and ATRIA scores included in the model, the CHADS2 score was significantly different between both groups (P = 0.002), while the ATRIA score was not (P = 0.58). In patients who were prescribed TT, 36.6% had a history of stroke or TIA compared with 10.9% in the DAPT group (P = 0.005). Additionally, the patients who were discharged on TT were more likely to have been treated with an OAC prior to admission, compared with those in the DAPT group (70% vs 17.1%; P < 0.001). We observed that there was proportionally more use of a BMS in patients with AF (41.5% of the 94 patients) compared with BMS being used in the whole cohort (15% of the 1,458 patients).There was no statistically significant difference in the likelihood of being discharged on TT based on whether patients were hospitalized at a community or academic hospital (44% vs. 56%, P = 0.42). Academic hospitals had the availability of a thrombosis service and they provided a consultation on 18% of the patients analyzed at those hospitals. The thrombosis service was generally involved in the care of patients with higher CHADS2 scores,and the involvement of the thrombosis service was associated with a significantly increased use of TT (P = 0.002). DISCUSSIONOur results indicate that approximately one-third of patients were prescribed TT at hospital discharge, while the remaining patients received DAPT alone. No patients received a combination of single antiplatelet therapy and an OAC. Although both the CHADS2 and ATRIA scores were significantly higher in the TT group, the CHADS2 score more strongly predicted the use of TT in our local practice. Our results also showed that OAC use prior to admission increased the probability of TT use upon discharge. Furthermore, the current study reveals that in patients discharged on TT, a combination of Aspirin, a P2Y12 inhibitor and NOAC were prescribed more often than conventional TT with warfarin despite the lack of clear evidence about their safety profile. 20,21An analysis of the AVIATOR registry, which included patients with a similar mean CHADS2 score as in our study (2.7 in the AVIATOR registry vs. 2.3 in our cohort) reported that 41.2% of patients were prescribed TT at discharge,22 compared with 31.9% in our cohort. This indicates that some practice variability exists among clinicians when considering treatment with TT in patients with similar risk profiles. The AVIATOR registry data also demonstrated that patients who were discharged on TT had a higher risk of stroke defined by their CHADS2 score but in contrast to our results, their bleeding risk score was not higher than the DAPT group. Our results were, however, consistent with another retrospective study within a large registry, which reported greater use of OAC at discharge among patients with both higher stroke and bleeding risk. 23 This observation highlights the important point that many major predictors of stroke, such as advanced age, are also important risk factors for bleeding.TT in our local clinical practice was used more selectively and was predominantly for those patients with a high CHADS2 score (≥3). Our data also show that clinicians favoured use of TT even in patients with higher bleeding risk despite the lack of robust evidence.24Our study was designed to describe practice patterns only, and therefore, one limitation was the inability to report patient outcomes following hospital discharge. Secondly, given the observational and retrospective nature of our study and the relatively small study cohort we are only able to describe associations. Thirdly, there are unmeasured variables such as frailty, patients’ overall goals of care, and personal preferences that could contribute to the ultimate decision for a given antithrombotic regimen, which were not captured in our study. Fourthly, the type and dose of NOAC were not collected in our study. Our study was unique in assessing practice parameters such as discharge settings (academic versus community hospitals) and describing the effect of the involvement of a thrombosis service in making treatment decisions.The choice of the most favourable antithrombotic regimen in patients with AF and ACS undergoing PCI remains an area of clinical debate. There were no patients in our study cohort discharged on a combination of a P2Y 12 inhibitor and warfarin alone, a regimen evaluated in the previously published WOEST trial.25 This observation indicates either a knowledge gap or reluctance among clinicians in applying the results of the WOEST study. The results of the PIONEER AF-PCI trial suggest that a WOEST study type strategy of reduced-dose rivaroxaban with single antiplatelet therapy (clopidogrel) is an attractive alternative to warfarin because of the substantial reduction in major bleeding. This trial has been criticized because it was not powered for ischemic events, had an open-label design, and tested doses of rivaroxaban that had not been previously evaluated.26 However, PIONEER AF-PCI and ongoing trials in this area will hopefully strengthen the body of evidence and lead to more informed clinical decision making and improved patient care. Despite the growing evidence in this area, the uptake will remain slow among clinicians until emergence of further robust evidence and variability of practice will persist as partially reflected in the current study.DisclosureThere was no dedicated funding for this study.None of the authors have any disclosures relevant to this study.REFERENCES1. 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