Academic literature on the topic 'Sucralfato'

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Journal articles on the topic "Sucralfato"

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Ayala Pío, Salomón, David Díaz, Manuel Palomino, Segundo Armas, and Juan Paz. "Efecto Protector de Croton palanostigma y Aloe frente a Injuria Aguda de Mucosa Gástrica inducida por Etanol en Ratas." Anales de la Facultad de Medicina 60, no. 1 (2014): 22. http://dx.doi.org/10.15381/anales.v60i1.4498.

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OBJETIVOS: Evaluar el grado de protección frente a la necrosis de la mucosa gástrica inducida por etanol con Croton palanostigma (Sangre de Grado) y Aloe vera, y compararlo con el de sucralfato y una suspensión de antiácido (AlOH3 +MgOH3+simeticona), en un modelo experimental estandarizado en ratas. MATERIAL Y MÉTODOS: Se evaluó a 56 animales, administrándoles en ayunas uno de 7 pretratamientos: solución salina, C. palanostigma (0,4 ó 0,8 mL/kg), A. vera (7,5 ó 3,2 mL/kg), sucralfato (500 mg/kg) o antiácido. Una hora más tarde, se administró por vía intragástrica 2 mL de etanol al 100%. Se rea
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Palomino, Miriam, Oscar Huamán, Elsa Béjar, Christian Palomino, and Justina Najarro. "Actividad antioxidante y gastroprotectora del extracto hidroalcohólico de hojas de Heliotropum arborescens L, en úlceras inducidas con etanol en estómago de ratas." Anales de la Facultad de Medicina 73 (May 7, 2013): 21. http://dx.doi.org/10.15381/anales.v73i1.2131.

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Objetivos: Evaluar la actividad antioxidante y protectora del extracto hidroalcohólico de Heliotropium arborescens L ‘cayaraja’ sobre la mucosa gástrica en úlceras inducidas en ratas. Evaluar el efecto antioxidante. Evaluar el grado de protección del extracto en estómago de ratas Diseño: Descriptivo transversal Institución: Facultad de Medicina UNMSM. material biológico: 48 ratas machos y 30 ratones. Intervenciones: Para evaluar el efecto protector se administró fármacos y extracto a 6 grupos: I control; II ranitidina; III sucralfato; IV, V y VI extracto 200, 400 y 600 mg/kg vía oral; luego, s
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Ayala Pío, Salomón, Hilda Jurupe, David Díaz, et al. "Efecto protector de látex desecado y fracción alcaloidea de Croton palanostigma frente a injuria de mucosa gástrica inducida por etanol en ratas." Anales de la Facultad de Medicina 62, no. 4 (2014): 317. http://dx.doi.org/10.15381/anales.v62i4.4205.

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OBJETIVOS: Evaluar el grado de protección de necrosis de la mucosa gástrica por etanol, con látex desecado y fracciones alcaloideas de C. palanostigma, en un modelo experimental estandarizado en ratas. Evaluar toxicidad subcrónica. MATERIAL Y MÉTODOS: Se evaluó 60 animales, administrándoles uno de 6 pretratamientos: solución salina, látex desecado de C. palanostigma 120 mg/kg, fracción alcaloidea de C. palanostigma 20 mg/kg, 35 mg/kg y 50 mg/kg y sucralfato 500 mg/kg. Una hora más tarde se aplicó por vía intragástrica 2 mL de etanol al 100%. Se realizó evaluación macroscópica y microscópica de
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Sandoval Vegas, Miguel Hernán, Janeth Tenorio Mucha, Aldo Tinco Jayo, Rudi A. Loli Ponce, and Segundo Calderón Pinillos. "Efecto antioxidante y citoprotector del tocosh de Solanum tuberosum ‘papa’ en la mucosa gástrica de animales de experimentación." Anales de la Facultad de Medicina 76, no. 1 (2015): 15. http://dx.doi.org/10.15381/anales.v76i1.11070.

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El tocosh es un producto alimenticio obtenido por una técnica de conservación andina y que tiene propiedades nutritivas y terapéuticas. Objetivo: Demostrar la capacidad antioxidante y el efecto citoprotector del tocosh de Solanum tuberosum ‘papa’ en la mucosa gástrica de animales de experimentación. Diseño: Experimental. Institución: Centro de Investigación de Bioquímica y Nutrición, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú. Material biológico: Tocosh seco y molido administrado a ratas albinas. Intervenciones: A 6 grupos de ratas albinas machos (200 ± 50 g) se
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Herencia Reyes, Vilma, Israel Rivera, Lucy E. Correa Lopez, and Jhony A. De La Cruz Vargas. "Efecto gastroprotector de un nutraceutico compuesto por Ocimum micranthum Willd (albahaca silvestre) frente a ulceras gastricas inducidas por etanol en ratas." Revista Peruana de Medicina Integrativa 3, no. 2 (2019): 91. http://dx.doi.org/10.26722/rpmi.2018.32.87.

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Objetivo: Investigar el efecto de los extractos acuosos en infusión y cocimiento de unnutraceutico compuesto de Ocimum micranthum Willd (ISHCATUL®), en un modelo deulcera gástrica inducida con etanol en ratas. Materiales y Métodos: Estudioexperimental. Se distribuyeron 25 ratas machos en cuatro grupos de estudio: 1)Control Negativo (Suero fisiológico 0.9% 1mL/100 g); 2) Control Positivo (Sucralfato500 mg/Kg); 3) Experimental 1 (Cocimiento a dosis 1mL/100 g); y 4) Experimental 2(Infusión a dosis 2mL. /100 g). Adicionalmente se utilizó una rata como blanco, parapoder realizar comparaciones media
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Champion, Malcolm C. "Therapeutic Options in the Treatment and Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Ulceration." Canadian Journal of Gastroenterology 4, no. 3 (1990): 113–19. http://dx.doi.org/10.1155/1990/826248.

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This article reviews the current status of H2receptor antagonists, omeprazole, sucralfate and misoprostol as therapeutic options for the prophylaxis and treatment of nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal ulceration. The efficacy of the Hz receptor antagonists appears to be restricted to prophylaxis and treatment of NSAID-induced duodenal ulcer disease. Omeprazole may have a place in the future treatment of NSAID-induced gastric ulcers. However, more studies are necessary to examine this drug's efficacy in both the prophylaxis and treatment of NSAID-induced ulcera
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McCullough, Ricky Wayne. "Regulatory Dichotomy of Sucralfate, Its history and the new Bioadhesive polymerized Sucralfate barrier therapy for Oral health, Oncology support and Gastrointestinal disorders." International Journal of Drug Regulatory Affairs 7, no. 3 (2019): 40–47. http://dx.doi.org/10.22270/ijdra.v7i3.343.

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Sucralfate is a biologically inert non-systemically acting compound. It requires polymerization for conversion into its biological active form, polymerized Sucralfate. Should this conversion occur in the body, using processes of the body to effect conversion subsequent to administering a dose, then the administered Sucralfate is a drug, as it enlists bodily functions to enact a chemical change. This form of Sucralfate should be regulated as drug. On the other hand, Sucralfate is manufactured as a polymerized product, requiring no bodily functions to enable its therapeutic effect, then this for
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Wallace, John L., Gerald P. Morris, Paul L. Beck, Todd E. Williamson, and Guy R. Gingras. "Effects of sucralfate on gastric prostaglandin and leukotriene synthesis: relationship to protective actions." Canadian Journal of Physiology and Pharmacology 66, no. 5 (1988): 666–70. http://dx.doi.org/10.1139/y88-105.

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The mechanism of the protective actions of sucralfate against ethanol-induced gastric mucosal damage in the rat has been investigated. In particular, the role of prostaglandins as mediators of such protection was assessed. Oral administration of sucralfate at a dose causing a significant reduction of ethanol-induced gastric damage (500 mg/kg) did not significantly alter gastric 6-ketoprostaglandin F1α synthesis. Pretreatment with indomethacin at a dose that inhibited gastric cyclooxygenase activity by an average of 88% did not affect the protective actions of sucralfate. To further investigate
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Koshariya, Mahim, Abhishek Shitole, Vibhore Agarwal, and S. Dave. "Role of topical Sucralfate in healing of burn wounds." International Surgery Journal 5, no. 9 (2018): 2995. http://dx.doi.org/10.18203/2349-2902.isj20183409.

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Background: Sucralfate is a basic aluminum salt of sucrose octasulphate which was orally taken for prevention and treatment of several gastrointestinal diseases. This study primarily aims to analyze whether sucralfate accelerates wound healing process in burn patients. The incidence of infection & relieve in pain in burn patients was also compared.Methods: This is an observational study carried out in the Department of General Surgery, Hamidia Hospital Bhopal on 50 patients divided into group 1 (sucralfate)and group 2 [a-sucralfate; b-silver sulfadiazine (SSD)]. Demographics, history, phys
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Martenson, James A., John W. Bollinger, Jeff A. Sloan, et al. "Sucralfate in the Prevention of Treatment-Induced Diarrhea in Patients Receiving Pelvic Radiation Therapy: A North Central Cancer Treatment Group Phase III Double-Blind Placebo-Controlled Trial." Journal of Clinical Oncology 18, no. 6 (2000): 1239–45. http://dx.doi.org/10.1200/jco.2000.18.6.1239.

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PURPOSE: Randomized studies have suggested that sucralfate is effective in mitigating diarrhea during pelvic radiation therapy (RT). This North Central Cancer Treatment Group study was undertaken to confirm the antidiarrheal effect of sucralfate. Several other measures of bowel function were also assessed.PATIENTS AND METHODS: Patients receiving pelvic RT to a minimum of 45 Gy at 1.7 to 2.1 Gy/d were eligible for the study. Patients were assigned randomly, in double-blind fashion, to receive sucralfate (1.5 g orally every 6 hours) or an identical looking placebo during pelvic RT.RESULTS: One h
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Dissertations / Theses on the topic "Sucralfato"

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Miura, Maurício Schreiner. "Uso de sucralfato e de clindamicina tópicos na analgesia pós-adenotonsilectomia em crianças." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/15251.

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Objetivo: A tonsilectomia, com ou sem adenoidectomia, é um dos procedimentos cirúrgicos mais realizados em otorrinolaringologia pediátrica. Dor é a principal causa de morbidade no período pós-operatório. Avaliou-se efeito do sucralfato e da clindamicina tópicos na redução da dor orofaríngea em crianças submetidas à adenotonsilectomia. Delineamento do Estudo: Ensaio clínico randomizado, duplo-cego. Pacientes e métodos: Avaliou-se 123 crianças de ambos sexos entre 4 e 12 anos de idade submetidas à adenotonsilectomia. Foram alocadas para receber clindamicina tópica, sucralfato tópico no ou placeb
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Aranzales, Jose Ramon Martinez. "Efeitos do óleo de milho e do sucralfato em equinos portadores de úlceras gástricas." Universidade Federal de Minas Gerais, 2012. http://hdl.handle.net/1843/BUBD-8ZUGB8.

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The Equine Gastric Ulcer Syndrome (EGUS) presents a high and variable occurrence in horses of different age groups and classes according to the activity they are carrying. The objective was evaluate the effects of corn oil and sucralfate in horses suffering from gastric ulcers. For this was used 15 horses divided into three groups. In the induction phase of ulcers, was used a combination of stall confinement and phenylbutazone (PBZ) in doses of 4.4 mg/kg/po/sid/5days with a single dose of 13.2 mg/kg/po on sixth day (GIII), single dose of 13.2 mg/kg/po on day six (GII) and the control group or
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Pommier, Jean-François. "Les mécanismes de défense de la muqueuse gastro-duodénale : le sucralfate et la cytoprotection dans le cadre de la maladie ulcéreuse." Bordeaux 2, 1991. http://www.theses.fr/1991BOR2P120.

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LASBASSES, CLAUDINE. "Prevention des ulceres gastro-duodenaux de stress : activite comparee du sucralfate et de la cimetidine : a propos de quatre-vingt-dix-sept cas dans un service de reanimation polyvalente." Bordeaux 2, 1988. http://www.theses.fr/1988BOR25165.

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Schober, Tina [Verfasser]. "Verhindert die frühzeitige Gabe von Sucralfat systemische Inflammationsreaktionen nach hämorrhagischem Schock? : Eine kontrollierte, randomisierte, experimentelle Studie am Schwein / Tina Schober." Aachen : Shaker, 2005. http://d-nb.info/118658856X/34.

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Stapleton, Graham Neil. "A study of the effects of sucralfate in the bile duct litigated pig peptic ulcer model with particular reference to the effects on the physico-chemical properties of gastric mucus and including comparisons with famotidine and misoprostol." Master's thesis, University of Cape Town, 1992. http://hdl.handle.net/11427/25727.

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Sucralfate is a drug that effectively heals duodenal, gastric and oesophageal ulcers. It is not absorbed systemically and it has been shown to act locally by coating the ulcer base. However when it was also shown to prevent stress ulcers and ethanolinduced gastric mucosa! lesions, it seemed likely that it acted in some way to improve the effectiveness of the gastric mucosa! barrier. Some investigators suggested that it did so by stimulating local prostaglandin release. The Slomiany group, on the basis of in vitro work on the effects of Sucralfate on pig gastric mucus, claimed that Sucralfate a
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Nondela, Babalwa Bukeka. "Correlation of 99mTc Sucralfate scan and endoscopic grading in caustic oesophageal injury: An observational analytic study at Red Cross War Memorial Children’s Hospital." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29701.

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Introduction: Technecium (Tc) 99m Sucralfate scan has been shown to be a reliable and non-invasive screening modality after caustic substance ingestion, followed by oesophagoscopy under general anaesthesia to grade the extent and severity of injury. Aim: To determine a correlation between the 99mTc Sucralfate scan and the endoscopy findings in children presenting with caustic oesophageal injury. Methods: An observational analytic study of children who had both 99mTc Sucralfate scan and endoscopy after caustic substance ingestion at Red Cross War Memorial Children’s Hospital in a period between
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MACAIGNE, OLIVIER. "Interet de la scintigraphie intestinale au sucralfate marque au technetium 99 metastable et de la scintigraphie aux granulocytes marques a l'indium 111 au cours des enterocolites cryptogenetiques." Lille 2, 1988. http://www.theses.fr/1988LIL2M237.

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Silva, Maria João Leal. "Influência de fármacos modificadores e protetores da secreção gástrica." Master's thesis, 2014. http://hdl.handle.net/10400.26/13075.

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Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz<br>A secreção de ácido clorídrico ocorre pelas células parietais do estômago através de enzimas H+/K+-ATPase. Os principais estimulantes da secreção de ácido no lúmen gástrico são a acetilcolina, a gastrina e a histamina, enquanto a somatostatina tem um efeito oposto. A terapêutica farmacológica de problemas relacionados com hipersecreção ácida e lesões gástricas pode envolver: antiácidos que atuam neutralizando o HCl no estômago; inibidores da bomba de protões que se ligam irreversivelmente à H+
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ZHOU, RUI-SHU, та 周瑞淑. "SUCRALFATE懸液劑之研究". Thesis, 1989. http://ndltd.ncl.edu.tw/handle/33739056810453100726.

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Books on the topic "Sucralfato"

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Hollander, Daniel, and Guido N. J. Tytgat, eds. Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/b102476.

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(Editor), Daniel Hollander, and G. N. Tytgat (Editor), eds. Sucralfate: From Basic Science to Bedside. Springer, 1995.

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Tytgat, Guido, and Daniel Hollander. Sucralfate: From Basic Science To The Bedside. Springer, 2013.

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Tytgat, Guido, and Daniel Hollander. Sucralfate: From Basic Science to the Bedside. Springer, 2013.

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Daniel, Hollander, and Tytgat G. N. J, eds. Sucralfate: From basic science to the bedside. Plenum Medical Book Co., 1995.

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Porro, G. Bianchi. Treatment of Digestive Disease With Sucralfate (Perspectives in Digestive Disease). Raven Pr, 1989.

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Book chapters on the topic "Sucralfato"

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Szabo, Sandor, Stefano Kusstatscher, Zsuzsa Sandor, Miki Nagata, Judah Folkman, and Y. Shing. "Sucralfate." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_16.

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Halter, F. "Pathophysiology of Peptic Ulcer Disease." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_1.

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Lucey, Michael R., and Tadataka Yamada. "Effect of Sucrose Octasulfate on Isolated Gastric Cells." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_10.

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Hills, Brian A. "Effect on Gastric Surfactant." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_11.

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Rachmilewitz, Daniel. "Stimulation of Mucosal Prostaglandins by Sucralfate." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_12.

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Louw, J. A., G. O. Young, T. A. Winter, and I. N. Marks. "Sucralfate and Helicobacter pylori." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_13.

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Kuwayama, Hajime. "Sucralfate and Cell Proliferation." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_14.

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Sandor, Zsuzsa, and Sandor Szabo. "Vascular Factors." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_15.

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Konturek, Stanislaw J., Jan W. Konturek, Tomasz Brzozowski, Bronislaw L. Slomiany, and Amelia Slomiany. "Effects of Sucralfate on Growth Factor Availability." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_17.

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Marks, I. N., and G. O. Young. "Duodenal Ulcer Therapy, “Acid Rebound,” and Early Relapse." In Sucralfate. Springer US, 1995. http://dx.doi.org/10.1007/978-0-585-32154-7_18.

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Conference papers on the topic "Sucralfato"

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Gascón Villacampa, A., M. Pio, M. Marin, N. Alzueta, D. Perez, and M. Castresana. "3PC-001 Magistral formulation of 10% sucralfate enemas in proctitis." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.82.

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BHANOT, RAVINDER D. "Nosocomial Pneumonia In Mechanically Ventilated Patients Receiving Ranitidine, Omeprazole or Sucralfate As Stress Ulcer Prophylaxis." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6039.

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