Dissertations / Theses: 'Sudden Infant Death Syndrome; Cot death'

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Howat, William James. "The pulmonary immunopathology of sudden infant death syndrome." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241962.

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Blair, Peter Sinclair Paul. "Assessing the changing risk factors associated with Sudden Infant Death Syndrome." Thesis, University of Bristol, 1998. http://hdl.handle.net/1983/275cdd77-5f8e-487d-8e8d-3aa62eea16e8.

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Wilks, Peter Andrew David. "An intelligent respiration monitor for infants considered to be at risk of sudden infant death syndrome." Thesis, University of Sussex, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357266.

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Pahal, Narinder Kaur. "A morphometric study of the phrenic nerve and diaphragm during late gestational and neonatal development." Thesis, Liverpool John Moores University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361503.

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Gantley, Madeleine. "Cultural constructions of infancy : an anthropological study of infant care in Cardiff." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1994. http://researchonline.lshtm.ac.uk/682273/.

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This thesis is about infancy, independence, and how medicalisation shapes mothers' perceptions of their infants. It draws on ethnographic research in Cardiff, undertaken during a period of heightened concern about the Sudden Infant Death Syndrome (SIDS), and funded by the Foundation for the Study of Infant Deaths. Three "cultural constructions" of infancy are juxtaposed: the vulnerable and constantly accompanied Bangladeshi infant, the Welsh or English infant encouraged towards independence, and the autonomous infant of epidemiological analysis. The thesis shows how the processes of medicalisation brought contrasting perceptions of infancy to light, suggesting that Bangladeshi women taking part in an "English for Pregnancy" project were not only learning language, but also learning about medicalised infant care. It argues too that health professionals shape the way in which mothers perceive their infants through the introduction of the language of "risk factors". The infant body itself emerged at the boundary of powerful systems of meaning. If the boundaries of the Bangladeshi infant body were blurred through constant contact, those of the Welsh or English infant were marked intermittently through alternating periods of solitude with "attention". Some Welsh and English mothers spoke of infants and their care in terms of the care of domestic animals, and the mothers' own ambivalence about their own animality, while some Bangladeshi mothers spoke of the spiritual power and vulnerability of infants, and in doing so articulated their links with Bangladesh. For health professionals the infant body was a site for demonstrating expertise through both research (which constructed ethnic minorities as 'natural') and recommendations for action. The thesis discusses the location of contemporary anthropology at cultural boundaries. Juxtaposing contrasting beliefs about infancy revealed very different perceptions of independence, marked in particular by contrasting perceptions of time, space, and the infant body itself.

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Beech, Darren James. "A stereological investigation of the development of the respiratory and renal systems of victims of sudden infant death syndrome." Thesis, Brunel University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363197.

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Wilson, Leigh Ann. "Sudden Unexpected Death in Infants (SUDI) and parental infant care: perspectives of general practitioners, nurses and parents living and working in the multicultural community of Western Sydney." University of Sydney, 2009. http://hdl.handle.net/2123/6275.

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Doctor of Public Health
For many years the major cause of infant mortality in NSW has been the result of Sudden Infant Death Syndrome (SIDS). Statistics show the area defined as 'Western Sydney' is no exception, and in 2002, a report prepared by the Epidemiology, Indicators, Evaluation and Research Unit (EIRE) in Western Sydney presented data indicating SIDS rates in the area were higher than the state average. In particular, two Local Government Areas (LGAs) had clusters of SIDS deaths. Previous Australian research identified a higher risk of SIDS and other causes of infant mortality in Aboriginal and Torres Strait Islander populations. The areas of Western Sydney where SIDS rates were higher than expected were home to Aboriginal, Torres Strait Islander and Pacific Island residents. The number of SIDS deaths in Aboriginal infants did not explain the higher than expected rate of SIDS in the areas under investigation. Studies undertaken in New Zealand and the Pacific Islands have identified higher than expected risk of SIDS in Maori and Pacific Island communities in those countries, although this has never been studied in Pacific Island residents living in Australia. The reasons for these communities exhibiting a higher than normal SIDS rate is not completely understood, but can be partially explained by behavioural practices which are known to impact adversely on the risk of SIDS. This study sought to investigate the level of knowledge concerning the prevention of sudden and unexpected death in infants (SUDI) in three key groups of infant caregivers: general practitioners, nurses and parents living or working in the area geographically defined by Sydney West Area Health Service (WSAHS). In addition, the study sought to identify any variation in knowledge of SIDS reduction strategies in the three groups under study, and to investigate factors influencing knowledge and practice in these participants. The study findings were then used as a basis on which to develop strategies and recommendations to enhance the delivery of safe sleeping messages through the health care system. Using a combination of qualitative and quantitative methods, this cross-sectional study highlights a number of issues around infant care practices and the major influences on new parents living in a multicultural community. Results of the study showed there is a large variation in knowledge around safe sleeping practices (including SIDS reduction strategies) in all the groups studied. Although educational campaigns are conducted regularly, many general practitioners and parents are confused about the key SIDS reduction messages and still place infants in sleeping positions considered unsafe. While nurses and midwives were aware of the SIDS reduction strategies, they still occasionally used infant sleeping positions considered unsafe. General practitioners born overseas in a country where English is not the first language were less likely to be familiar with safe sleeping messages, including SIDS reduction strategies. Families from a Culturally and Linguistically Diverse (CALD) background were less likely to have seen SIDS information in their own language than families who spoke English, and as a result were more likely to use traditional methods of infant care, including co-sleeping with siblings and parents and side or tummy sleeping. CALD parents were more likely to rely on herbal remedies and friends and family for assistance, than English speaking parents who accessed health professionals as the first point of call when infants were unwell. The study identified a relatively recent practice, which until reported in this study, has not been documented in the literature. The practice of draping infant prams with blankets originated from the Cancer Council of Australia guidelines which recommend covering a pram with a light muslin wrap to protect infants’ skin from the sun. It appears parents have misinterpreted this message and are covering infant prams with blankets to encourage sleep, even when sun exposure is not an issue. Research suggests that poor air quality around the head of an infant may affect an infant’s arousal response. While no research has been conducted on the air quality around an infants head when covered by a heavy blanket in a pram, it is possible based on research into air quality around infants, that that this practice may increase the risk of sudden and unexpected death in an infant. In conclusion, this study found that multiple changes to the SIDS reduction messages since the initial ‘Reduce the Risks’ Campaign have led to confusion about ways of preventing SIDS in GPs, nurses and parents in Western Sydney. The study makes seven recommendations aimed at improving knowledge of safe sleeping practices in these groups, and optimizing health outcomes for infants using a collaborative approach to service delivery and future initiatives.

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Kräutle, Franz-Georg. "Struktur und Funktion humaner Acyl-CoA-Dehydrogenasen Untersuchungen zum 'Sudden infant death syndrome' /." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963175017.

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Kemp, Philip M. (Philip Marcus). "A Forensic Marker for a Genetic Disease Often Misdiagnosed as Sudden Infant Death Syndrome (SIDS)." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc500567/.

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Sudden Infant Death (SIDS) has been associated with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid oxidation. Blood and tissue samples from a large cohort of SIDS victims were analyzed for the presence of dodecanoic acid (C₁₂) by gas chromatography. A subgroup of these cases had a significantly higher blood concentration than age-matched controls, suggesting MCAD deficiency. An animal study using Sprague-Dawley rats was done to mimic the effects of MCAD deficiency. Significantly increased blood concentrations of dodecanoic acid were observed. Decreased values in heart and liver were puzzling findings. The data indicate that dodecanoic acid is a blood marker for MCAD deficiency.

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Roman-Lopez, Carmen R. E. "Studies on developmental patterns of biotin-containing enzymes and regulation of acetyl CoA carboxylase /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487325740720117.

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Kolikof, Joshua S. "Diagnostic drift in sudden infant death syndrome." Thesis, Boston University, 2013. https://hdl.handle.net/2144/21196.

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Thesis (M.A.) PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
INTRODUCTION: In the years that followed the 1994 Back to Sleep Campaign (BSC), a public health initiative designed to prevent Sudden Infant Death Syndrome (SIDS), the prevalence of SIDS decreased by nearly 50%. However, recent research questions the decline in SIDS with an appreciation of contemporaneous factors which may have contributed to it. There is a growing recognition that other, often indiscernible causes of Sudden Unexpected Infant Deaths (SUID) have increased prevalence rates. Several researchers have addressed the possibility of the effects of a diagnostic drift. OBJECTIVE: To evaluate the impact of certain contemporaneous factors on the decline in the prevalence of Sudden Infant Death Syndrome. METHODS: We examined a historically significant time period surrounding the implementation of the BSC, 1984-2009. It is a time-period that incorporates mortality statistics prior to the BSC, as well as immediately following. We utilized 1984-2009 mortality data obtained from the Center for Disease Control and Prevention and evaluated the following prevalence rates: SIDS, unknown and unspecified causes, Accidental Strangulation and Suffocation in Bed (ASSB), and Neglect. We then amalgamated unknown and unspecified causes, ASSB and Neglect into a single representation of non-SIDS SUID. We then proceeded to perform an analysis on these prevalence rates to determine linear trends. RESULTS: All-cause mortality rate decreased linearly by about .929 per 100,000 per year (p<.0001, β=-.929). SIDS mortality rates also experienced a significant decline of about .951 per 100,000 deaths per year (p<.0001, β=-.951). In contrast, the SUID cohort prevalence increased significantly with a rate of .930 per 100,000 per year (p<.0001, β=.930). DISCUSSION: Over our study period, SIDS declined significantly, but by 2001 it experienced a stagnant decline that was different than that from 1984-2000. From 2001 to 2009, our SUID cohort increased dramatically. It is our conclusion that the potential exists for a possible diagnostic drift from SIDS to these other SUID.
2031-01-01

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Davidson-Olsson, Isis Cherie. "Sudden Infant Death Syndrome : mothers' experiences of parenting." Thesis, University of Hertfordshire, 2013. http://hdl.handle.net/2299/10401.

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Background: The death of a child has been found to have long term consequences for both individual and family functioning. This is particularly true for bereaved siblings who have been found to be at increased risk of developing mental health difficulties in later life. Literature on parental bereavement proposes that the parenting phenomenon, such as replacement child syndrome, subsequent child syndrome and the parenting paradox, which can emerge after the death of a child, may account for this. However, there is very little research on these labels of observed parenting phenomenon and, as a result, any hypothesis offered remains under elaborated. In addition, limited evidence suggests that, due to the sudden, unexpected and unexplained nature of the loss, SIDS parents are more likely to experience a greater degree of distress and adjustment difficulties than other perinatally bereaved populations. Given this, it could be hypothesised that SIDS parents may be likely to experience these parenting phenomena. Despite this, however, SIDS remains a neglected area of research. Aims: As a consequence of this research gap, the study aims to explore mothers’ experiences of parenting in their transition from being a parent unaffected by Sudden Infant Death Syndrome to a parent affected by Sudden Infant Death Syndrome. Methodology: Semi-structured interviews were conducted with seven mothers who had experienced an incident of Sudden Infant Death Syndrome. The interviews were then transcribed and analysed using Interpretative Phenomenological Analysis (IPA). Results: Five master themes emerged from the analysis: ‘Channelling the Parent Within’, a naturally developing and responsive parenting style that is facilitated by internal mechanisms, such as flexibility and confidence; ‘Parenting Outside of Yourself’, a parenting style that develops in the aftermath of a SIDS event, which is characterised by self doubt and a reliance on external mechanisms such as reassurance and restriction; ‘Restoration Through You’, the restorative effect of the subsequent and surviving children, which allows vindication and re-establishes happiness; ‘The Bitter Restoration’, a restoration that encompasses internal knowledge and external evidence of loss, including a disrupted family composition and a continued awareness of existential threat; ‘A Disruptive Appreciation’, the development of a greater appreciation for the subsequent and surviving children that impacts discipline and incorporates indulgence. These, along with the subthemes contributing to them, are presented as a narrative account. Conclusion: The results imply that mothers who have experienced a SIDS event shift into a permissive and anxious style of parenting which is characterised by safety behaviours. A model of parenting in the aftermath of SIDS has been proposed in order to explain the underlying cognitions and processes which drive this behaviour and the factors which serve to maintain it. By doing this it is hoped that, when working with bereaved parents and siblings, clinicians will be better positioned to frame parenting practices and intervene at a cognitive level.

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Khorsandi, Mehdi. "Brainstem Gangliosides in Suddden Infant Death Syndrome." Thesis, North Texas State University, 1987. https://digital.library.unt.edu/ark:/67531/metadc504326/.

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Recent studies have shown that the Sudden Infant Death Syndrome (SIDS) is related to abnormal control of respiration (Ischemic degeneration of the brainstem may play an important role in altered respiratory control leading to death). In our studies we have examined brainstem ganglioside compositions in samples derived from SIDS victims and appropriate controls. Gangliosides are acidic glycosphingolipids that contain sialic acid. The high concentration of gangliosides in the central nervous system (CNS) implies that these lipids play an important role in CNS function. Some studies have indicated that gangliosides may function as receptor site determinants or modifiers, and in neural transmission. In our studies we used the Tettamanti, et al methodology to extract gangliosides, and High Performance Thin Layer Chromatography (HPTLC) and laser densitometry techniques for ganglioside analysis. The results of these analyses are being employed to establish lipid profile patterns to determine if there are significant variations in these lipid patterns between SIDS and control groups.

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Mooney, Jennifer Anne. "Statistical analysis of seasonality in sudden infant death syndrome." Thesis, University of Aberdeen, 2002. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU160368.

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SIDS deaths exhibit a seasonal pattern with a winter peak, and the cause of this seasonality is unknown. The seasonal pattern is not symmetrical and it has been thought that the relatively flat winter peak may be due to the existence of more than one underlying population, where each population corresponds to a different cause of seasonality. In this thesis, mixtures of von Mises distributions have been fitted using maximum likelihood estimation to determine whether there is heterogeneity in the UK SIDS data. Various computational problems arise with the fitting procedures and attempts to tackle these for the SIDS data are discussed. A bootstrap likelihood ratio method is used to assess the number of components in the mixture, and its properties are investigated by simulation. Changes in the seasonal pattern since the 'back to sleep' campaign are also examined as any differences might give clues as to what caused the fall in 1992, and what the reasons for the remaining deaths might be. The von Mises distributions are compared with cosinor analysis and skewed regression models to determine the most appropriate method for modelling the seasonality in the data. Mixtures of Weibull and Gamma distributions are used to model the age distribution in SIDS. The motivation for this was to determine whether there are two or more groups of babies whose age-at-death distributions are different and to examine any changes since the 'back to sleep' campaign. Generalised linear models have previously been used to determine whether month of birth is an independent risk factor in addition to month of death and age at death. In this thesis, mixtures of these generalised linear models have been fitted using the EM algorithm to determine whether there are different groups of babies with different risks. Childhood type 1 diabetes mellitus is another condition which exhibits a seasonal pattern in diagnosis. The thesis concludes by considering analysis of these data using the mixture modelling approach.

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Cowgill, Brittany M. "Rest Uneasy: Sudden Infant Death Syndrome in Twentieth-century America." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439282125.

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Myers, Patricia D. "The Association of Maternal Pregnancy Complications and Sudden Infant Death Syndrome." [Tampa, Fla.] : University of South Florida, 2003. http://purl.fcla.edu/fcla/etd/SFE0000068.

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Abreu, e. Silva Fernando Antonio. "Clinical studies of breathing during sleep and sudden infant death syndrome." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/30126.

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Oquendo, Javier. "Elemental Analysis of Brainstem in Victims of Sudden Infant Death Syndrome." Thesis, University of North Texas, 1988. https://digital.library.unt.edu/ark:/67531/metadc500370/.

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A brainstem-related abnormality in respiratory control appears to be one of the most compelling mechanisms for sudden infant death syndrome (SIDS). The elements calcium, copper, iron, potassium, magnesium, sodium, phosphorus, sulfur, and zinc were analyzed by inductively coupled plasma atomic emission spectroscopy in the brainstem of 30 infants who died from SIDS and 10 infants who died from other causes (control). No differences were found between SIDS and control for any element except for more calcium in the SIDS group. A multivariate analysis of the data failed to group the majority of SIDS and control subjects in different clusters. Further research is required to determine the biological significance of the higher calcium found in the SIDS group.,

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Gurbutt, Dawne J. "Making and re-making motherhood : maternal grief following sudden infant death syndrome." Thesis, Lancaster University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429974.

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Smoleniec, John Stefan. "Preterm fetal behavioural states and the risk of sudden infant death syndrome." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324366.

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Martin, Kathryn Rosalys. "The association between shared sleeping arrangements and sudden infant death syndrome (SIDS)." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1666117511&sid=4&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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22

Bai, Zemin. "Sudden infant death syndrome among twins in the United States 1995--1997." Thesis, University of Ottawa (Canada), 2007. http://hdl.handle.net/10393/27809.

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Sudden infant death syndrome (SIDS) constitutes an increasing proportion of infant deaths, and twins have a higher risk of SIDS than singletons. This retrospective cohort study, based on the 1995-1997 Matched Multiple Birth File of the United States, examined risk factors of SIDS and non-SIDS deaths using generalized estimating equations, and investigated competing risks of SIDS using survival analysis. The three unique characteristics of twins, namely birth weight discordance, birth order within pairs, and sex combinations, were not associated with SIDS, while they were related to non-SIDS deaths. Lower maternal education, younger maternal age, and maternal smoking during pregnancy were the strongest risk factors of SIDS among twins. Preterm birth and fetal growth restriction were determinants of infant deaths, including both SIDS and non-SIDS deaths. In conclusion, social factors and common biological factors are important risk factors for SIDS among twins while the biological factors unique to twins are not.

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Storer, Lisa Clair Dawn. "The possible significance of cytomegalovirus in infant mortality." Thesis, University of Sheffield, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247228.

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Kräutle, Franz-Georg. "Struktur und Funktion humaner Acyl-CoA-Dehydrogenasen : Untersuchungen zum 'Sudden Infant Death Syndrom' /." [S.l. : s.n.], 2001. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB9673772.

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Wilson, C. Elizabeth. "The environmental niche of Aboriginal infants, possible implications for sudden infant death syndrome." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ35048.pdf.

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Gordon, Ann Elizabeth. "The protective effect of breast feeding in relation to sudden infant death syndrome." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/22256.

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A model has been proposed which suggests that SIDS victims die from uncontrolled inflammatory responses to bacterial toxins. Bacteria associated with SIDS include Staphylococcus aureus and Clostridium perfringens. Most SIDS deaths occur during 2 - 4 months of age when infants have decreasing levels of maternal antibodies to infectious agents. Most deaths occur during the early hours of the morning. Adults are more susceptible to inflammatory responses at night due to lower cortisol levels associated with circadian rhythm patterns. Infants develop these patterns between 7 - 22 weeks, at which time their night-time cortisol levels drop dramatically. Breast fed infants develop these patterns significantly earlier than formula fed infants. Human buffy coats were used to investigate pro-inflammatory cytokine production in response to TSST-1 and to investigate the effect of cortisol levels observed in infants before and after circadian rhythm pattern development. The bacterial binding studies indicate protection associated with breast feeding in relation to SIDS could be due partly to enhanced clearance of bacterial aggregates. Human IgA antibodies in breast milk might neutralise bacterial toxins on mucosal surfaces. If the switch to the circadian rhythm pattern occurs in an infant when maternal antibodies are present or an infant is receivng IgA in breast milk, the infant might be able to neutralise a challenge with the toxins; however, if the switch occurs in an infant when antibody levels are low or an infant is formula fed, lower night-time cortisol levels might be insufficient to control inflammatory responses induced by bacterial toxins alone or in combination with other infections.

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Kilb, Joanne Riley. "DESENSITIZATION: A PROCESS OF PARENTS' ADJUSTMENT TO THE HOME APNEA MONITORING OF THEIR INFANT." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/292058.

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Moore, Alison Jane. "Quantitative histomorphometric analysis of the bone growth plate in infancy : a comparative study between SIDS and normal subjects /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09MSM/09msmm821.pdf.

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Kennedy, Kimberly A. "Family communication following a S.I.D.S, . death : a narrative perspective /." free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3101028.

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Essery, Stephen D. "Studies on the role of the pyrogenic staphylococcal toxins in sudden infant death syndrome." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/21229.

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The aim of this study was to examine how infection might play a role in SIDS in relation to developmental and environmental risk factors identified in epidemiological studies by examining the binding of bacterial toxins to human cells and their effects, singly and in combination on induction of inflammatory mediators. There is a correlation between the incidence of SIDS, isolation of Staphylococcus aureus and expression of the Lewis^a blood group antigen in the 2 to 4 month age range. Lewis^a has previously been shown to act as a surface receptor for certain bacteria on human epithelial cells, the first stage of this study was to develop a screening method to detect adhesions that bind Lewis^a on toxigenic strains of S. aureus and other bacteria isolated from SIDS infants. Additional experiments indicated that some of the superantigenic toxins of S. aureus utilise this antigen as a receptor on monocytes and are capable of stimulating the production of inflammatory mediators from these cells. The pertussis toxin of B. pertussis is capable of binding to Lewis^a and Lewis^x and it has been suggested that asymptomatic whooping is one cause of SIDS. Changes in the age range of SIDS infants were observed between 1988 and 1994, after the DPT immunisation schedule was changed from 3 months to 2 months of age in October 1990. The protective effect of DPT immunisation suggested in several large epidemiological studies was examined with reference to antigenic cross reactivity between the DPT vaccine and the staphylococcal toxins. Results obtained in enzyme linked immunosorbent assays (ELISA) indicated that antibodies cross-reactive with the staphylococcal toxins were produced by rabbits in response to DPT immunisation. Assays for nitric oxide production by human monocytes in response to the toxins indicated that the antibodies were able to neutralise partially some of the inflammatory activities of the toxins.

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Young, Jeanine. "Night-time behaviour and interactions between mothers and their infants of low risk for SIDS : a longitudinal study of room-sharing and bed-sharing." Thesis, University of Bristol, 1999. http://hdl.handle.net/1983/2c6375b8-11f3-4450-8012-cd8e90cb7038.

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Nguyen, Tracy Thuy. "Preventing Sudden Infant Death Syndrome: Assessment of Advanced Practice Nurses' Knowledge, Attitudes, and Current Practices." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/593629.

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Background: In the United States, sudden infant death syndrome (SIDS) is the leading cause of death in children less than one year old, and the third leading case of death in infants. In 1992, the American Academy of Pediatrics (AAP) recommended to place infants supine for sleep, and the SIDS rate declined by 50%. Despite these efforts, the SIDS rate has plateaued since 2001. With the growing number of advanced practices nurses (APN) providing care to pregnant women and infants, APNs are in a position to educate new parents on preventing SIDS using the 2011 AAP safe sleep recommendations. Yet, knowledge, attitudes, and current practices of APNs regarding SIDS risk reduction are unknown in the State of Arizona. Purpose: The purpose of this Doctor of Nursing Practice (DNP) project was to assess the attitudes, knowledge, and current practices of APNs regarding risk reduction strategies. Methods: This study was a descriptive quantitative cross-sectional survey design. Target study participants included APNs that provided care to pregnant women and/or infants up to 12 months old. The study was conducted in the State of Arizona through online surveys using the Qualtrics software. The study participants' knowledge, attitudes, and current practices were assessed using an adapted validated survey tool that included multiple choice items and responses using Likert scales. Results: Twenty-three APNs completed the survey. Knowledge about SIDs was average, with a mean score of 74% correct. Although most APNs felt it was important to educate parents about SIDS, only three-quarters of APNs provided verbal education to parents, and less than half of participants provided written information to parents. To decrease the SIDS rate, it is necessary for APNs to gain more knowledge about current safe sleep recommendations.

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Harris-Mims, Jameelah. "Perceptions of Sudden Infant Death Syndrome among African American Women Living in SPA 6 of Los Angeles County." Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/321519.

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Sudden Infant Death Syndrome (SIDS) is a serious public health issue in this country and a major contributor to infant mortality in African American populations. African Americans have one of the highest rates of SIDS, some of which is due to increased risk factors for SIDS, such as prone sleeping and bed-sharing, as well as a lack of adherence to the SIDS risk reducing recommendations. Little is understood about this lack of adherence in the African American population or how to effectively address it but some research suggests a link between parental health beliefs of SIDS and the risk reducing recommendations and the implementation of these recommendations. This study used quantitative methods to gather data about the health beliefs and perceptions of SIDS among African American women living in Service Planning Area (SPA) Six of Los Angeles County to better understand the link between beliefs about SIDS and how this relates to implementation of the safe infant sleeping recommendations, specifically bed-sharing and prone sleeping. A self-administered questionnaire was developed to collect data using the Health Belief Model and several of its concepts as a guiding framework to assist with the construction of the questionnaire. The questionnaire was distributed electronically through the survey software program, Survey Monkey and analyzed using statistical software, SPSS. Exploratory factor analysis found the questionnaire reliable and valid upon the removal of four items, including the construct of cues to action. The new 19-item questionnaire suggested that the women felt that SIDS was a big problem but didn't feel as susceptible. There was also a clear confusion about prone sleeping position. Overall, the data suggests a need for tailored educational campaigns in African American communities to increase awareness of and susceptibility to SIDS and stressing the benefits of supine sleeping position.

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Råsten, Almqvist Petra. "Sudden infant death syndrome : a medico-legal study of related cardiovascular, toxicological and genetic findings /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-167-5.

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Pease, Anna Susan. "Factors influencing infant care practices in the sleep environment among families at high risk of sudden infant death syndrome." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702488.

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Introduction. Advice for reducing the risk of Sudden Infant Death Syndrome (SIDS) by modifying the infant sleep environment has led to significant reductions in the number of babies who die. The highest burden of SIDS now lies with the most deprived families in society, where rates remain higher than in the general population. This thesis employed a mixed methods approach to examine knowledge and attitudes to SIDS risk reduction advice and explore the factors that influence decision making for the infant sleep environment among families most at risk. Methods. The four parts to this programme of work included: 1) A systematic review of the literature to reveal how mothers' knowledge of SIDS risk reduction has been measured and provide a suitable tool for use in a quantitative survey. 2) An analysis of longitudinal postal questionnaires from birth to late infancy to assess whether a high risk scoring system for SIDS based on routine demographics identifies risky infant care practices. 3) A quantitative survey of mothers recruited from health visitor-led clinics in deprived areas of Bristol, UK to measure mothers' knowledge and attitudes to SIDS advice. 4) A qualitative survey using home interviews with mothers of infants at higher risk of SIDS to determine decision making processes for the infant sleep environment. Results. The systematic review screened over 3000 papers and uncovered a useful tool for measuring knowledge of SIDS risks. The analysis of 591 postal questionnaires found that a scoring system of demographic characteristics can pick up on differences in infant care for a higher risk group, especially sleeping position and breastfeeding. The face-to-face survey with 400 mothers found poorer knowledge of SIDS risks in a higher risk group using the same scoring system and home interviews with 20 mothers most at risk gave insights into the complex challenges of night time infant care for this group. The interviews suggested that mothers are influenced by family and friends, their own self-efficacy, beliefs they hold about infant safety and care and their perceived barriers to following the recommended advice. Conclusions. This work confirms that families at higher risk for SIDS have poorer knowledge of the risk factors and are more likely to engage in sleep practices that may put their infants at further risk of SIDS. It also confirms that decision-making for infant care is interconnected with social contexts and psychological constructs that can help or hinder when it comes to safe sleep. Where good reasons for following advice were lacking, mothers would fill in the blanks with their own interpretations that risk supporting unsafe sleep decisions. Interventions that target groups of parents where the risks of SIDS are higher, need to consider social influences, beliefs and understanding behind the safer sleep messages if they are to be effective and engage this group in change.

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Stengel, Katrina. "A case study in efforts to prevent sudden infant death syndrome : continuity and specificity of practice." Thesis, Lancaster University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289075.

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Saadi, Abdulrahman Towfeeq. "Factors enhancing adherence of toxigenic bacteria to epithelial cells in relation to sudden infant death syndrome." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/21508.

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This study tests the hypothesis that the Lewis^a antigen, expressed by 80-90% of infants between the ages of 2-4 months, is one of the host receptors for two toxigenic bacteria species suggested to be involved in cot death, Staphylococcus aureus and Bordetella pertussis. Although respiratory viruses are often isolated from SIDS infants, there is no direct evidence for their involvement in these deaths; however, this study examined the effect of virus infection on binding of S. aureus and B. pertussis to epithelial cells in culture. By flow cytometry, binding of three toxigenic strains of S. aureus to buccal epithelial cells (BEC) from non-secretors (which usually express large amounts of Lewis^a) was significantly greater than to cells of secretors. Pre-treatment of epithelial cells with monoclonal anti-Lewis^a, anti-type 1 precursor or anti-Lewis^x significantly reduced bacterial binding; and binding of S. aureus was significantly correlated with the amount of Lewis^a present on the epithelial cells. Binding of B. pertussis to epithelial cells was also significantly inhibited by pre-treatment of the cells with anti-Lewis^a or anti-Lewis^x. A 67 kDa protein was isolated from cell membrane preparations of S. aureus (NCTC 10655) by affinity adsorption with synthetic Lewis^a antigen conjugated to Synsorb beads. Pre-treatment of BEC with the purified protein reduced binding of staphylococcal strains to a greater extent than with the material not bound to the Synsorb beads. Respiratory Syncytial Virus (RSV) infects about 50% of infants by the first year of life and it is often isolated from infants with SIDS. RSV-infected HEp-2 cells bound significantly more S. aureus or B. pertussis than uninfected cells.

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Boex, Toby John. "Antimony, cadmium, lead and mercury in the prenatal and postnatal period." Thesis, University of Wolverhampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300987.

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Ansari, Tahera Iqbal. "Stereological analysis of SIDS-linked micro-anatomical anomalies in specific regions of the brain, phrenic nerve and diaphragm." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266251.

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Kelly, Barbara M. "The analysis of biological fluids for acylcarnitines." Thesis, Open University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326566.

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Xu, Xueyan. "Prediction of life-threatening events in infants using heart rate variability measurements." Morgantown, W. Va. : [West Virginia University Libraries], 2002. http://etd.wvu.edu/templates/showETD.cfm?recnum=2288.

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Thesis (Ph. D.)--West Virginia University, 2002.
Title from document title page. Document formatted into pages; contains viii, 250 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 240-250).

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Bencs, Nicole. "Developing Educational Material To Promote Awareness Of Nicotine Use As A Significant Risk Factor For Sudden Infant Death Syndrome." Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/338754.

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Introduction and Rationale: Sudden infant death syndrome (SIDS) continues to be the leading cause of death in infants 28 days to 12 months old and the third leading cause of infant mortality (CDC, 2014; Task Force on SIDS, 2011a). SIDS has no identifiable cause although many hypotheses have existed and there are many known risk factors. Nicotine use is the second most modifiable risk factor for SIDS and to date there is no national public education campaign. Formal education is needed. Written education materials, such as brochures, are an effective way to increase knowledge and awareness of a health topic. Purpose and Objective: The purpose of this DNP Project was to create an educational brochure about SIDS and nicotine as a significant modifiable risk factor. The brochure is directed towards pregnant women and women with infants less than 12 months of age. The objective was to educate and inform mothers about SIDS, nicotine and its relation to SIDS, and the importance of abstaining from nicotine during and after pregnancy. Methods: The brochure was created using the Health Belief Model (HBM) as a framework. The HBM was used to explain health behavior modifications and was used as a foundation for education interventions. The model has successfully been applied to explain other preventative health behaviors and provide health education in various contexts. Results: The brochure was evaluated by two subject matter experts who have published peer reviewed articles using the HBM. Both subject matter experts found the HBM applied to the brochure appropriately. In their opinion, the content of the brochure should have positive impact for health modification in women who use nicotine and are pregnant or have a child less than 12 months of age. Conclusions: This DNP Project demonstrated SIDS as a current significant health problem and identified maternal nicotine use as the second most modifiable risk factor. Due to lack of current public education, a brochure was created using the HBM as a framework. Subject matter experts stated the brochure was created based on the HBM and will likely a have positive health influence on the intended population.

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Teske, Anja. "Variations in the human hsp60 gene between cases of sudden infant death syndrome and non-affected children." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976146797.

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Donnelly, William T. "Serotonin Signaling in the Nucleus Tractus Solitarius Modulates the Laryngeal Chemoreflex| Implications for Sudden Infant Death Syndrome." Thesis, Dartmouth College, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10145494.

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Sudden infant death syndrome (SIDS) occurs when a sleeping infant experiences a challenge to cardiorespiratory homeostasis which it fails to overcome. Analyses of brain tissue from SIDS cases from around the world consistently show abnormalities in the brainstem serotonin systems. These include increased numbers of neurons that test positive for serotonergic markers, but have an immature phenotype, reduced brain tissue serotonin concentrations and decreased serotonin receptor binding in projection sites important to cardiorespiratory homeostasis, including the nucleus of the solitary tract (NTS). The NTS is of particular interest in the pathophysiology of SIDS because it is the integration center for afferent projections involved in eliciting several apnea-inducing reflexes long suspected of contributing to SIDS. The laryngeal chemoreflex (LCR), an airway protective reflex which is initiated when water, acidic solutions, or low [Cl-] solutions activate chemoreceptors in the larynx, is one such reflex. In infants, inhibitory reflex responses to hypoxia (apnea, bradycardia, decreased metabolic activity) that are adaptive for a fetal environment that precludes the possibility of the fetus acquiring more oxygen by increasing breathing, persist for some time into the postnatal period. Therefore, hypoxia resulting from apnea caused by the LCR can result in a cataclysmic downward spiral of apnea, followed by increasing hypoxic inhibition of respiration, which ultimately leads to SIDS. We hypothesized that increasing serotonin signaling in the brainstems of rat pups would shorten the apnea and respiratory disruption caused by eliciting the LCR. We have shown that both intracisternal injections of serotonin, and microinjections of serotonin into the caudal NTS, dramatically shorten the LCR. This effect is also seen after microinjection into the NTS of the 5-HT3 specific agonist CPG. Chemical stimulation by microinjection of AMPA of neurons in the raphe obscurus, some of which send serotonergic projections to the NTS, also shortens the LCR, but this effect is blocked by prior injection of a 5-HT3 antagonist in the NTS. Our work suggests that serotonergic projections to the NTS from the caudal raphe may play an important role in limiting the duration of apnea following inhibitory reflexes like the LCR and in the subsequent restoration of eupnea.

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Huang, Hai. "Biophysical Characterization of Three SCN5A Mutations Linked to Long QT Syndrome Type 3, Sudden Infant Death Syndrome, and Atrial Fibrillation." Thesis, Université Laval, 2010. http://www.theses.ulaval.ca/2010/27250/27250.pdf.

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Andersen, Danielle Louise. "Development of neurotransmitter receptors in the human brain and vulnerability to perinatal asphyxia and sudden infant death syndrome /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17412.pdf.

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George, Mary. "Urea and Non-Protein Nitrogen Metabolism in Infants : With Special Reference to the Sudden Infant Death Syndrome (SIDS)." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5141-1/.

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Davet, Dominique. "A nonlinear model of heart rate variability applied to cardiorespiratory interactions in adults and infants." Thesis, Georgia Institute of Technology, 1988. http://hdl.handle.net/1853/17614.

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Machaalani, Rita. "Brainstem pathology in SIDS and in a comparative piglet model." University of Sydney. Medicine, 2003. http://hdl.handle.net/2123/605.

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This thesis tests the hypothesis that increased neuronal cell death in SIDS infants is related to the ability of risk factors, such as prone sleeping, to expose infants to intermittent hypercapnic hypoxia (IHH). Based on the hypothesis that the NMDA system is linked to neuronal death, by way of excitotoxicity, correlations were also sought between cell death and changes in NMDA receptor (NR1) expression in brainstem nuclei controlling cardiorespiratory function. The first aim of this study was to verify that increased neuronal cell death occurs in SIDS infants. To verify a piglet model of SIDS risk factors, brainstem changes were examined in piglets exposed to IHH, and comparisons were made to changes seen in SIDS infants. The NMDA receptor was characterised in controls for both the human infant and the piglet groups. Comparisons of neuronal changes were made with SIDS infants, and piglets exposed to IHH. Non-radioactive in-situ hybridisation and immunohistochemistry were performed on formalin fixed and paraffin embedded brainstem tissue to identify markers of cell death (caspase-3, active caspase-3, and TUNEL), and to examine NR1 mRNA and protein expressions. Staining was quantified using computerised image analysis software. Eight nuclei from the brainstem medulla (caudal in piglets, and mid in infants), and two nuclei from the rostral pons (infants) were studied. The first dataset included human infants aged 1-6 months with a diagnosis of SIDS (n=15) or non-SIDS (n=10). The second dataset comprised developing piglets aged 13-14 days, with controls (n=6), against those exposed to IHH for 2 (n=6) or 4 (n=5) days. Increased neuronal cell death was not verified in the SIDS infants, but abnormalities in NR1 expression were present in selected nuclei of the medulla. Piglets exposed to IHH had increased neuronal cell death and changes in NR1 in selected nuclei of the medulla. There was also a positive correlation between increased cell death and high NR1 levels. Preliminary data showed that SIDS infants who usually slept prone had some differences in NR1 compared to those who did not usually sleep prone. From these findings, it was concluded that IHH may underlie the abnormalities in NMDA receptor expression that are present in the brainstem of SIDS infants. Although IHH can induce an increase in neuronal cell death, its significance in the aetiology of SIDS is not known. In piglets, IHH induced cell death correlated with high NMDA expression in some brainstem nuclei, supporting the hypothesis that excitotoxicity may be involved in the mechanism for cell death. Moreover, this thesis presents for the first time, �preliminary pathological proof� of an association between prone sleeping and abnormal NMDA receptor expression in SIDS infants.

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Pettersson, Madeleine. "Bloggning som copingstrategi : Änglamammors användning av copingstrategier i bloggtexter." Thesis, Uppsala universitet, Religionspsykologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-273711.

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The aim of my work was to analyze how three bloggers, who lost a child to sud- den infant death syndrome SIDS, used different rituals and coping strategies in their blogs. I analyzed how these mothers, through blogging on the Internet, ex- press their grief, what kind of rituals they have performed in the grieving process, and whether these rituals can be seen as part of a coping strategy to deal with the grief. My analysis was based on a deductive approach with the help of the coping theory which MarieAnne Ekedahls (2001) used in her research and the theories about ritualization which Carin Åblad Lundström (2010) used in her. In my analy- sis, I made a transverse text analysis using the analysis program Open Code. I used Open Code to structure and upload my material, and analyzed it along Eke- dahls (2001) coping theory and Åblad Lundström (2010) theories about ritualiza- tions as a coping strategy when dealing with SIDS. The essay was divided into three different parts. Part I was based on Ekedahls (2001) coping model to analyze how the bloggers produce various coping strate- gies in their texts. The conclusion was that all coping strategies were prominent in the blogs. Part II, in which Åblad Lundström’s (2010) model was used, estab- lished that ritualization was useful when dealing with death. The rituals were thus also the prominent component in all of the three blogs on a religious, private and social level, and both in private and in public. Finally, these two theories were combined in Part III, where it was possible to conclude that the appropriate rituals could be connected with one or more of the designed coping strategies. Coping strategies involve either preserving or reconstructing methods and ways of mov- ing on, while rituals result in a contact with the individual's inner or outer worlds. In this way, it was possible to see rituals as a coping strategy. Both coping strate- gies and rituals were combined, so none of the bloggers used only one strategy or ritual, but used many of them when dealing with death.

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Dissertations / Theses on the topic 'Sudden Infant Death Syndrome; Cot death'

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