Journal articles: 'Sulfonace BODIPY'

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Mehra, Sukanya, and Pooja Chadha. "Bioaccumulation and toxicity of 2-naphthalene sulfonate: an intermediate compound used in textile industry." Toxicology Research 9, no. 2 (2020): 127–36. http://dx.doi.org/10.1093/toxres/tfaa008.

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Abstract The aromatic compounds substituted with sulfonate groups, being xenobiotic, resist biodegradation in the environment and tend to accumulate up to toxic levels. The hydrophilic sulfonated group makes these compounds highly water soluble and they tend to pass through water-treatment plants. The release of untreated effluents from these industries results in pollution of water bodies affecting aquatic fauna. Thus, the toxicity regarding these compounds is of major concern. The 2-naphthalene sulfonate is a sulfonated aromatic compound being widely used in textile industries. Being non-biodegradable concern regarding its toxicity has risen. Thus in the light of above facts, the present study was undertaken to determine the toxicity of 2-naphthalene sulfonate in blood cells of Channa punctatus. For this, LD50 was determined and after selection of sublethal doses oxidative stress, genotoxicity and bioaccumulation were studied. For oxidative stress determination, biochemical markers such as malondialdehyde content and activities of superoxide dismutase, catalase, and glutathione-S-transferase were studied. Genotoxicity was studied using comet and micronucleus assay. Significant increase in oxidative stress and DNA damage in the exposed groups as compared to control group (P ≤ 0.05) was observed till 96 h. However, decreased values of all the studied parameters at 720 h (30 days) indicate repair capacity of fish. Further, the bio accumulative potential of 2-naphthalene sulfonate was assessed in blood plasma using high-performance liquid chromatography. The study revealed the toxic potential of 2-naphthalene sulfonate to aquatic organisms thus stressed on the need for the implementation of stringent policies regarding the management of such toxic compounds.

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Kim, Jiyoung, and Youngmi Kim. "A water-soluble sulfonate-BODIPY based fluorescent probe for selective detection of HOCl/OCl−in aqueous media." Analyst 139, no. 12 (2014): 2986–89. http://dx.doi.org/10.1039/c4an00466c.

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A water-soluble sulfonate-BODIPY dye1was developed for the selective detection of HOCl/OCl<sup>−</sup>in aqueous buffer solution. The probe, which displays extremely weak fluorescence owing to efficient photoinduced electron transfer (PeT) from the pendant catechol donor, responds to HOCl/OCl<sup>−</sup>through a dramatic enhancement of its fluorescence intensity.

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Lv, Fan, Xing Guo, Hao Wu та ін. "Direct sulfonylation of BODIPY dyes with sodium sulfinates through oxidative radical hydrogen substitution at the α-position". Chemical Communications 56, № 99 (2020): 15577–80. http://dx.doi.org/10.1039/d0cc07259a.

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Ali, Abbas Mohammed, Jian Shao, Jia-Xin Wang, Qiu-Yun Chen, Yang Li, and Ling-Ling Qu. "A Fluorescent Visual Proton Donor and Photoacid Sterilant Based on Sulfonate‐conjugated BODIPY." Journal of Fluorescence 31, no. 2 (2021): 501–7. http://dx.doi.org/10.1007/s10895-021-02682-8.

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Xu, Bo, Xiaoli Ji, Xiaojiao Chen, et al. "Effect of perfluorooctane sulfonate on pluripotency and differentiation factors in mouse embryoid bodies." Toxicology 328 (February 2015): 160–67. http://dx.doi.org/10.1016/j.tox.2014.12.010.

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Ziaja-Sołtys, Marta, Wojciech Radzki, Jakub Nowak, et al. "Processed Fruiting Bodies of Lentinus edodes as a Source of Biologically Active Polysaccharides." Applied Sciences 10, no. 2 (2020): 470. http://dx.doi.org/10.3390/app10020470.

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Water soluble polysaccharides (WSP) were isolated from Lentinus edodes fruiting bodies. The mushrooms were previously subjected to various processing techniques which included blanching, boiling, and fermenting with lactic acid bacteria. Therefore, the impact of processing on the content and biological activities of WSP was established. Non-processed fruiting bodies contained 10.70 ± 0.09 mg/g fw. Boiling caused ~12% decrease in the amount of WSP, while blanched and fermented mushrooms showed ~6% decline. Fourier transform infrared spectroscopy analysis (FTIR) confirmed the presence of β-glycosidic links, whereas due to size exclusion chromatography 216 kDa and 11 kDa molecules were detected. WSP exhibited antioxidant potential in FRAP (ferric ion reducing antioxidant power) and ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) assays. Cytotoxic properties were determined on MCF-7 and T47D human breast cell lines using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) test. Both biological activities decreased as the result of boiling and fermenting.

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Eniola, Kehinde I. Temitope. "Effect of additional carbon source on biodegradation of linear alkylbenzene sulfonate by las-utilizing bacteria." Journal of Xenobiotics 1, no. 1 (2011): 2. http://dx.doi.org/10.4081/xeno.2011.e2.

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Aerobic biodegradation of linear alkylbenzene sulfonate (LAS) by LAS-utilizing bacteria (LUB) in the presence of other sources of carbon (glucose and soluble starch) was examined. Biodegradation of LAS was monitored as primary degradation in terms of half-life (t&frac12;) of the surfactant. Biodegradation of LAS by the individual LUB was slower in the presence of Glucose. Biodegradation of the surfactant by the various consortia of LUB was slower in the presence of the carbon sources: t&frac12; increased to 3 days. The rates of biodegradation by the consortia can be ranked as: four-membered (t&frac12;=9 days) &gt; three-membered (t&frac12;=9 to 13 days) &gt; two-membered consortia (t&frac12;=10 to 15 days). Generally, degradation in the presence of the carbon sources was faster with the consortia than the individual species. Degradation of the surfactant by the LUB was generally fastest in the absence of additional carbon sources. The possible role of additional carbon sources in persistence of surfactant in water bodies and the application of the observation in management of LAS-containing-effluent is suggested.

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Zhang, Xiao Bo. "Synthesis and Properties of Inorganic Organic Composite UV Shielding Materials with Supramolecular Structure." Applied Mechanics and Materials 552 (June 2014): 251–56. http://dx.doi.org/10.4028/www.scientific.net/amm.552.251.

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In this paper, 2 - (2 - hydroxy - 5 - sulfonic acid-phenyl) -5 - amino-2H-benzotriazole had been inserted into the precursor layer by ion exchange method using Mg/Zn/Al-CO3-LDHs as precursor. The samples obtained were characterized by XRD, SEM, laser particle size analyzer, IR, UV spectra and TG-DTA. The results show that, by controlling the conditions, the CO32- ions of precursor layer can be replaced by HASB, producing strong supramolecular interaction between the main bodies. The material was obtained in the ratio of MgZn2Al, can achieve the UV absorption maximum and better thermal stability, resulting in a new type of inorganic - organic composite supramolecular UV shielding materials.

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Xu, Bo, Xiaoli Ji, Xiaojiao Chen, et al. "Corrigendum to “Effect of perfluorooctane sulfonate on pluripotency and differentiation factors in mouse embryoid bodies” [Toxicology 328 (2015) 160–167]." Toxicology 411 (January 2019): 181–82. http://dx.doi.org/10.1016/j.tox.2018.10.010.

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Seidel, Ulrike, Kai Lüersen, Patricia Huebbe, and Gerald Rimbach. "Taurine Enhances Iron-Related Proteins and Reduces Lipid Peroxidation in Differentiated C2C12 Myotubes." Antioxidants 9, no. 11 (2020): 1071. http://dx.doi.org/10.3390/antiox9111071.

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Taurine is a nonproteinogenic amino sulfonic acid in mammals. Interestingly, skeletal muscle is unable to synthesize taurine endogenously, and the processing of muscular taurine changes throughout ageing and under specific pathophysiological conditions, such as muscular dystrophy. Ageing and disease are also associated with altered iron metabolism, especially when there is an excess of labile iron. The present study addresses the question of whether taurine connects cytoprotective effects and redox homeostasis in a previously unknown iron-dependent manner. Using cultured differentiated C2C12 myotubes, the impact of taurine on markers of lipid peroxidation, redox-sensitive enzymes and iron-related proteins was studied. Significant increases in the heme protein myoglobin and the iron storage protein ferritin were observed in response to taurine treatment. Taurine supplementation reduced lipid peroxidation and BODIPY oxidation by ~60 and 25%, respectively. Furthermore, the mRNA levels of redox-sensitive heme oxygenase (Hmox1), catalase (Cat) and glutamate-cysteine ligase (Gclc) and the total cellular glutathione content were lower in taurine-supplemented cells than they were in the control cells. We suggest that taurine may inhibit the initiation and propagation of lipid peroxidation by lowering basal levels of cellular stress, perhaps through reduction of the cellular labile iron pool.

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Mukhopadhyay, Debaditya, Ferhan Ayaydin, Nagamalleswari Kolli, et al. "SUSP1 antagonizes formation of highly SUMO2/3-conjugated species." Journal of Cell Biology 174, no. 7 (2006): 939–49. http://dx.doi.org/10.1083/jcb.200510103.

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Small ubiquitin-related modifier (SUMO) processing and deconjugation are mediated by sentrin-specific proteases/ubiquitin-like proteases (SENP/Ulps). We show that SUMO-specific protease 1 (SUSP1), a mammalian SENP/Ulp, localizes within the nucleoplasm. SUSP1 depletion within cell lines expressing enhanced green fluorescent protein (EGFP) fusions to individual SUMO paralogues caused redistribution of EGFP-SUMO2 and -SUMO3, particularly into promyelocytic leukemia (PML) bodies. Further analysis suggested that this change resulted primarily from a deficit of SUMO2/3-deconjugation activity. Under these circumstances, PML bodies became enlarged and increased in number. We did not observe a comparable redistribution of EGFP-SUMO1. We have investigated the specificity of SUSP1 using vinyl sulfone inhibitors and model substrates. We found that SUSP1 has a strong paralogue bias toward SUMO2/3 and that it acts preferentially on substrates containing three or more SUMO2/3 moieties. Together, our findings argue that SUSP1 may play a specialized role in dismantling highly conjugated SUMO2 and -3 species that is critical for PML body maintenance.

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Ulrich, Uta, Matthias Pfannerstill, Guido Ostendorp, and Nicola Fohrer. "Omnipresent distribution of herbicides and their transformation products in all water body types of an agricultural landscape in the North German Lowland." Environmental Science and Pollution Research 28, no. 32 (2021): 44183–99. http://dx.doi.org/10.1007/s11356-021-13626-x.

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AbstractThe research of the environmental fate of pesticides has demonstrated that applied compounds are altered in their molecular structure over time and are distributed within the environment. To assess the risk for contamination by transformation products (TP) of the herbicides flufenacet and metazachlor, the following four water body types were sampled in a small-scale catchment of 50 km2 in 2015/2016: tile drainage water, stream water, shallow groundwater, and drinking water of private wells. The TP were omnipresent in every type of water body, more frequently and in concentrations up to 10 times higher than their parent compounds. Especially metazachlor sulfonic acid, metazachlor oxalic acid, and flufenacet oxalic acid were detected in almost every drainage and stream sample. The transformation process leads to more mobile and more persistent molecules resulting in higher detection frequencies and concentrations, which can even occur a year or more after the application of the parent compound. The vulnerability of shallow groundwater and private drinking water wells to leaching compounds is proved by numerous positives of metazachlor-TP with maximum concentrations of 0.7 μg L−1 (drinking water) and 20 μg L−1 (shallow groundwater) of metazachlor sulfonic acid. Rainfall events during the application period cause high discharge of the parent compound and lower release of TP. Later rainfall events lead to high displacement of TP. For an integrated risk assessment of water bodies, the environmental behavior of pesticide-TP has to be included into regular state-of-the-art water quality monitoring.

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Kishimoto, Naoyuki, and Masanori Kobayashi. "Effects of three additives on the removal of perfluorooctane sulfonate (PFOS) by coagulation using ferric chloride or aluminum sulfate." Water Science and Technology 73, no. 12 (2016): 2971–77. http://dx.doi.org/10.2166/wst.2016.161.

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Abstract Perfluorooctanesulfonic acid and its salts (PFOS) are emerging contaminants with long half-lives in water and human bodies. Accordingly, PFOS removal from water streams is required for controlling the PFOS pollution. To provide a simple PFOS separation technology, effects of three additives, powdered activated carbon (PAC), gelatin, and cetyltrimethylammonium bromide (CTAB), on the PFOS removal by coagulation with ferric chloride or aluminum sulfate were investigated in this study. As a result, coagulation with PAC or CTAB addition was effective in the PFOS removal, though the conventional coagulation and coagulation with gelatin addition were ineffective. A PFOS removal efficiency of over 90% was observed for the CTAB dose of over 1.6 μM (0.58 mg/L) and for the PAC dose of over 40 mg/L, and that of over 95% was achieved by the CTAB dose of over 2.4 μM (0.87 mg/L), when the initial PFOS concentration was 1.84 μM. The positive effect of CTAB would be caused by micelle formation, which was enhanced by both the association of hydrophobic tails and the electrostatic attraction of hydrophilic heads of PFOS and CTAB. Thus, a linear cationic surfactant of CTAB was concluded to be an effective additive for the PFOS removal by coagulation.

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Gao, Xiong, Jiayi Qi, Chi-Tang Ho, et al. "Purification, Physicochemical Properties, and Antioxidant Activities of Two Low-Molecular-Weight Polysaccharides from Ganoderma leucocontextum Fruiting Bodies." Antioxidants 10, no. 7 (2021): 1145. http://dx.doi.org/10.3390/antiox10071145.

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Two low-molecular-weight polysaccharides (GLP-1 and GLP-2) were purified from Ganoderma leucocontextum fruiting bodies, and their physicochemical properties and antioxidant activities were investigated and compared in this study. The results showed that GLP-1 and GLP-2 were mainly composed of mannose, glucose, galactose, xylose, and arabinose, with weight-average molecular weights of 6.31 and 14.07 kDa, respectively. Additionally, GLP-1 and GLP-2 had a similar chain conformation, crystal structure, and molecular surface morphology. Moreover, GLP-1 exhibited stronger antioxidant activities than GLP-2 in five different assays: 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), hydroxyl radical, superoxide anion radical, ferric reducing antioxidant power (FRAP), and oxygen radical antioxidant capacity (ORAC). The main linkage types of GLP-1 were found to be →4)-α-D-Glcp-(1→, →4)-β-D-Glcp-(1→, →3)-β-D-Glcp-(1→, →6)-β-D-Galp-(1→, →6)-α-D-Glcp-(1→, →4,6)-α-D-Glcp-(1→, and Glcp-(1→ by methylation analysis and nuclear magnetic resonance (NMR) spectroscopy. In addition, GLP-1 could protect NIH3T3 cells against tert-butyl hydroperoxide (tBHP)-induced oxidative damage by increasing catalase (CAT) and glutathione peroxidase (GSH-Px) activities, elevating the glutathione/oxidized glutathione (GSH/GSSG) ratio, and decreasing the malondialdehyde (MDA) level. These findings indicated that GLP-1 could be explored as a potential antioxidant agent for application in functional foods.

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Nagai, Masaru, Maki Kawata, Hisayuki Watanabe, et al. "Important role of fungal intracellular laccase for melanin synthesis: purification and characterization of an intracellular laccase from Lentinula edodes fruit bodies." Microbiology 149, no. 9 (2003): 2455–62. http://dx.doi.org/10.1099/mic.0.26414-0.

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A laccase (EC 1.10.3.2) was isolated from the fully browned gills of Lentinula edodes fruit bodies. The enzyme was purified to a homogeneous preparation using hydrophobic, cation-exchange and size-exclusion chromatography. SDS-PAGE analysis showed the purified laccase, Lcc 2, to be a monomeric protein of 58·0 kDa. The enzyme had an isoelectric point of around pH 6·9. The optimum pH for enzyme activity was around 3·0 against 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt (ABTS), and it was most active at 40 °C and stable up to 50 °C. The enzyme contained 8·6 % carbohydrate and some copper atoms. The enzyme oxidized ABTS, p-phenylenediamine, pyrogallol, guaiacol, 2,6-dimethoxyphenol, catechol and ferulic acid, but not veratryl alcohol and tyrosine. β-(3,4-Dihydroxyphenyl)alanine (l-DOPA), which was not oxidized by a laccase previously reported from the culture filtrate of L. edodes, was also oxidized by Lcc 2, and the oxidative product of l-dopa was identified as l-DOPA quinone by HPLC analysis. Lcc 2 was able to oxidize phenolic compounds extracted from fresh gills to brown-coloured products, suggesting a role for laccase in melanin synthesis in this strain.

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Han, Deming, Yingge Ma, Cheng Huang, et al. "Occurrence and source apportionment of perfluoroalkyl acids (PFAAs) in the atmosphere in China." Atmospheric Chemistry and Physics 19, no. 22 (2019): 14107–17. http://dx.doi.org/10.5194/acp-19-14107-2019.

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Abstract. Perfluoroalkyl acids (PFAAs) are a form of toxic pollutant that can be transported across the globe and accumulated in the bodies of wildlife and humans. A nationwide geographical investigation considering atmospheric PFAAs via a passive air sampler (PAS) based on XAD (a styrene–divinylbenzene copolymer) was conducted in 23 different provinces/municipalities/autonomous regions in China, which provides an excellent chance to investigate their occurrences, spatial trends, and potential sources. The total atmospheric concentrations of 13 PFAAs (n=268) were 6.19–292.57 pg m−3, with an average value of 39.84±28.08 pg m−3, which were higher than other urban levels but lower than point source measurements. Perfluorooctanoic acid (PFOA) was the dominant PFAA (20.6 %), followed by perfluorohexanoic acid (PFHxA), perfluorooctane sulfonate (PFOS), and perfluoroheptanoic acid (PFPeA). An increasing seasonal trend of PFAA concentrations was shown as summer < autumn < spring < winter, which may be initiated by stagnant meteorological conditions. Spatially, the content of PFAAs displayed a declining gradient trend of central China > northern China > eastern China > north-eastern China > south-western China > north-western China > southern China, and Henan contributed the largest proportion of PFAAs. Four sources of PFAAs were identified using a positive matrix factorization (PMF) model, including PFOS-based products (26.1 %), products based on PFOA and perfluorononanoic acid (PFNA; 36.6 %), degradation products of fluorotelomer-based products (15.5 %), and an unknown source (21.8 %).

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Wang, Cuifang, Xuemin Liu, Chenlei Lian, Jiaying Ke, and Jieqing Liu. "Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum." Molecules 24, no. 23 (2019): 4353. http://dx.doi.org/10.3390/molecules24234353.

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Reactive oxygen/nitrogen species generated in the human body can cause oxidative damage associated with many degenerative diseases such as atherosclerosis, dementia, coronary heart diseases, aging, and cancer. There is a great interest in developing new antioxidants from Ganoderma fungus due to its low toxicity. As part of our ongoing search for antioxidative constituents from the fruiting bodies of Ganoderma lucidum, the chemical constituents were investigated and seven secondary metabolites, including one new lanostane triterpene (1), two known aromatic meroterpenoids (6–7), and four known triterpenes (2–5), were isolated by a series of chromatographic methods. The structures of the seven compounds were elucidated by spectroscopic techniques. The isolated compounds were tested in vitro for antioxidant potencies and neuroprotective activities against H2O2 and aged Aβ-induced cell death in SH-SY5Y cells. As a result, compounds 1, 6, and 7 exhibited potent antioxidant and neuroprotective activities. Additionally, all isolated compounds were tested for radical scavenging activities. Compounds 6 and 7 showed the comparable free radical scavenging activities with the standard drug in both ABTS (2, 2’-azobis (3-ethylbenzothiazole-6-sulfonaic acid)) and ORAC (oxygen radical absorbance capacity) experiments. The results from this study suggested that G. lucidum and its metabolites (especially the meroterpenoids) may be potential functional food ingredients for the antioxidation and prevention of neurogenerative diseases.

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Kiss, Attila, Petra Grünvald, Márta Ladányi та ін. "Heat Treatment of Reishi Medicinal Mushroom (Ganoderma lingzhi) Basidiocarp Enhanced Its β-glucan Solubility, Antioxidant Capacity and Lactogenic Properties". Foods 10, № 9 (2021): 2015. http://dx.doi.org/10.3390/foods10092015.

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The effect of heat treatment on dried fruiting bodies of Reishi medicinal mushroom (Ganoderma lingzhi) is investigated. Control and samples treated for 20 min at temperatures of 70, 120, 150 and 180 °C were subjected for their free radical scavenging capacity, different glucans and total phenolic content determination. The growth rate of Escherichia coli and Lactobacillus casei supplemented with control and heat-treated samples is also investigated. The roasted mushroom samples at 150 °C and 180 °C showed the highest level of β-glucan (37.82%) and free radical scavenging capacity on 2,2-diphenyl-1-picrylhidrazyl (DPPH•) and 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+). The content of total phenolics (TPC) was also influenced by heat treatment and significantly higher TPC values were recorded in samples treated at 120 °C and 150 °C. The presence of reducing sugars was only detected after heat treatment at 150 °C (0.23%) and at 180 °C (0.57%). The heat treatments at 120, 150 and 180 °C, significantly attenuated the number of colony-forming units (CFU) of pathogenic E. coli, in a linear relationship with an elevated temperature. The supplementation of heat-treated Reishi mushroom at 120 °C resulted in the highest growth rate of probiotic L. casei. The obtained results in this study revealed the significant effect of short-term heat treatment by enhancing the antioxidant capacity, β-glucan solubility and prebiotic property of the dried basidiocarp of Reishi mushroom.

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Kaur, Sandeep, Ajay Kumar, Sharad Thakur, et al. "Antioxidant, Antiproliferative and Apoptosis-Inducing Efficacy of Fractions from Cassia fistula L. Leaves." Antioxidants 9, no. 2 (2020): 173. http://dx.doi.org/10.3390/antiox9020173.

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Cassia fistula L. is a highly admirable traditional medicinal plant used for the treatment of various diseases and disorders. The present study was performed to divulge the antioxidant, antiproliferative, and apoptosis-inducing efficacy of fractions from C. fistula leaves. The hexane (CaLH fraction), chloroform (CaLC fraction), ethyl acetate (CaLE fraction), n-butanol (CaLB fraction), and aqueous (CaLA fraction) were sequentially fractionated from 80% methanolic (CaLM extract) of C. fistula leaves. The CaLE fraction was fractionated using column chromatography to yield a pure compound, which was characterized as Epiafzelechin (CFL1) based on 1H, 13C, and DEPT135 NMR. Among these fractions, CaLE and isolated CFL1 fractions exhibited an effective antioxidant potential in Ferric ion reducing power, (2,2’-azino-bis (3-ethylbenzothiazoline -6-sulfonic acid)) cation radical scavenging, and nitric oxide radical scavenging assays. Epiafzelechin was investigated for its antiproliferative effects against MG-63 (osteosarcoma), IMR-32 (neuroblastoma), and PC-3 (prostate adenocarcinoma), and was found to inhibit cell proliferation with a GI50 value of 8.73, 9.15, and 11.8 μM respectively. MG-63 cells underwent apoptotic cell death on treatment with Epiafzelechin as the cells showed the formation of apoptotic bodies, enhanced reactive oxygen species (ROS) generation, mitochondrial membrane depolarization along with an increase in early apoptotic cell population analyzed using Annexin V-FITC/PI double staining assay. Cells showed cell cycle arrest at the G0/G1 phase accompanied by a downregulation in the expression levels of p-Akt (Protein kinase B), p-GSK-3β (Glycogen synthase kinase-3 beta), and Bcl-xl (B-cell lymphoma-extra large) proteins. RT-PCR (Real time-polymerase chain reaction) analysis revealed downregulation in the gene expression level of β-catenin and CDK2 (cyclin-dependent kinases-2) while it upregulated the expression level of caspase-8 and p53 genes in MG-63 cells.

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Junttila, Vähä, Perkola, et al. "PFASs in Finnish Rivers and Fish and the Loading of PFASs to the Baltic Sea." Water 11, no. 4 (2019): 870. http://dx.doi.org/10.3390/w11040870.

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The concentrations of per- and polyfluoroalkyl substances (PFASs) in the Finnish aquatic environment were measured in riverine waters and in inland, coastal and open sea fish. In addition, the PFAS load to the Baltic Sea from 11 rivers was calculated. Measurements show that PFASs, including restricted perfluorooctane sulfonic acid (PFOS), are widely present in the Finnish aquatic environment. At three out of 45 sampling sites, the concentration of PFOS in fish exceeded the environmental quality standard (EQS) of the Water Framework Directive (WFD). The annual average (AA) ∑23PFAS concentration in surface waters ranged from 1.8 to 42 ng L−1 and the concentration of PFOS exceeded the AA-EQS in three out of 13 water bodies. In European perch (Perca fluviatilis) and Baltic herring (Clupea harengus membras), the ∑PFAS concentration ranged from 0.98 to 1 µg kg−1 f.w. (fresh weight) and from 0.2 to 2.4 µg kg−1 f.w., respectively. The highest concentrations in both surface water and fish were found in waters of southern Finland. The riverine export of ∑10PFAS to the Baltic Sea from individual rivers ranged from 0.4 kg yr−1 to 18 kg yr−1. PFAS concentrations in fish of point-source-polluted sites and coastal sites were higher compared to fish of open sea or diffusely polluted sites. The PFAS profiles in surface waters of background sites were different from other sites. This study shows that PFASs are widely found in the Finnish aquatic environment. Different PFAS profiles in samples from background areas and densely populated areas indicate diverse sources of PFASs. Although atmospheric deposition has a substantial influence on PFAS occurrence in remote areas, it is not the dominant source of all PFASs to the aquatic environment of Finland. Rather, wastewaters and presumably contaminated land areas are major sources of PFASs to this aquatic environment.

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Lv, Xin, Taihe Han, Yi Wu, Boran Zhang, and Wei Guo. "Improving the fluorescence brightness of distyryl Bodipys by inhibiting the twisted intramolecular charge transfer excited state." Chemical Communications, 2021. http://dx.doi.org/10.1039/d1cc03360c.

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The fluorescence brightness of distyryl Bodipys was substantially improved by employing sulfone- and quaternary ammonium-modified piperidines as auxochromes instead of conventional dialkylamino auxochromes.

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I.T. Eniola, Kehinde, and Albert B. Olayemi. "Linear Alkylbenzene Sulfonate tolerance in bacteria isolated from sediment of tropical water bodies polluted with detergents." Revista de Biología Tropical 56, no. 4 (2007). http://dx.doi.org/10.15517/rbt.v56i4.5745.

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Bliziotis, Nikolaos G., Leo A. J. Kluijtmans, Sebastian Soto, et al. "Pre- versus post-operative untargeted plasma nuclear magnetic resonance spectroscopy metabolomics of pheochromocytoma and paraganglioma." Endocrine, September 18, 2021. http://dx.doi.org/10.1007/s12020-021-02858-z.

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Abstract Purpose Pheochromocytomas and Paragangliomas (PPGL) result in chronic catecholamine excess and serious health complications. A recent study obtained a metabolic signature in plasma from PPGL patients; however, its targeted nature may have generated an incomplete picture and a broader approach could provide additional insights. We aimed to characterize the plasma metabolome of PPGL patients before and after surgery, using an untargeted approach, and to broaden the scope of the investigated metabolic impact of these tumors. Design A cohort of 36 PPGL patients was investigated. Blood plasma samples were collected before and after surgical tumor removal, in association with clinical and tumor characteristics. Methods Plasma samples were analyzed using untargeted nuclear magnetic resonance (NMR) spectroscopy metabolomics. The data were evaluated using a combination of uni- and multi-variate statistical methods. Results Before surgery, patients with a nonadrenergic tumor could be distinguished from those with an adrenergic tumor based on their metabolic profiles. Tyrosine levels were significantly higher in patients with high compared to those with low BMI. Comparing subgroups of pre-operative samples with their post-operative counterparts, we found a metabolic signature that included ketone bodies, glucose, organic acids, methanol, dimethyl sulfone and amino acids. Three signals with unclear identities were found to be affected. Conclusions Our study suggests that the pathways of glucose and ketone body homeostasis are affected in PPGL patients. BMI-related metabolite levels were also found to be altered, potentially linking muscle atrophy to PPGL. At baseline, patient metabolomes could be discriminated based on their catecholamine phenotype.

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Journal articles on the topic 'Sulfonace BODIPY'

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